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Conserved domains on  [gi|488383788|ref|WP_002453173|]
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MULTISPECIES: BCCT family transporter [Staphylococcus]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-504 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 632.57  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   1 MNSSSHEKKNKKFS-SVFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKL 79
Cdd:COG1292    1 MSDKNKEKFKKKIDpPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  80 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPP-TADPKTTAAYTEALRSTFFHWGFHAWAIYGVVAL 158
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 159 ALAYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIV 238
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 239 IVTILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNGqkRDWMST 318
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 319 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVLGIETGKKHP----ELFKMSPETQLFG 394
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 395 VFHHIPMGIVLSIIALLLIASFFITSADSATFVLGMQTTFGSLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQ 474
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 488383788 475 SAAIISAFPFSFVVIMMMISFYKDANQERK 504
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-504 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 632.57  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   1 MNSSSHEKKNKKFS-SVFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKL 79
Cdd:COG1292    1 MSDKNKEKFKKKIDpPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  80 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPP-TADPKTTAAYTEALRSTFFHWGFHAWAIYGVVAL 158
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 159 ALAYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIV 238
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 239 IVTILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNGqkRDWMST 318
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 319 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVLGIETGKKHP----ELFKMSPETQLFG 394
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 395 VFHHIPMGIVLSIIALLLIASFFITSADSATFVLGMQTTFGSLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQ 474
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 488383788 475 SAAIISAFPFSFVVIMMMISFYKDANQERK 504
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
16-502 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 599.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   16 VFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISW 95
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   96 FAMLFSAGMGIGLVFYGAAEPMADFAA-PPTADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALALAYAQFRKGEPGLIS 174
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  175 RTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSK 254
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  255 GIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALnGQKRDWMSTWTLYYWGWWLSWSPFV 334
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  335 GVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVLGIETGKKHP----ELFKMSPETQLFGVFHHIPMGIVLSIIAL 410
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  411 LLIASFFITSADSATFVLGMQTTFGSLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQSAAIISAFPFSFVVIM 490
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 488383788  491 MMISFYKDANQE 502
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
54-502 5.38e-161

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 466.06  E-value: 5.38e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   54 GWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPPT-ADPKTTA 132
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFgAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  133 AYTEALRSTFFHWGFHAWAIYGVVALALAYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMG 212
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  213 ALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTG 292
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  293 SLLNTFLFNSLDTAALNGqKRDWMSTWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVL 372
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDG-KGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  373 GIETGKKH-----PELFKMSPETQLFGVFHHIPMGIVLSIIALLLIASFFITSADSATFVLG-MQTTFGSLN--PSIMVK 444
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLGeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488383788  445 VTWGVAQALIAFVLLLAGGgdgskALNAIQSAAIISAFPFSFVVIMMMISFYKDANQE 502
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-497 1.03e-124

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 380.97  E-value: 1.03e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   1 MNSSSHEKKNKKFSSVFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLK 80
Cdd:PRK09928   4 TDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  81 LGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPPTADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALAL 160
Cdd:PRK09928  84 LGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMAL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 161 AYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIV 240
Cdd:PRK09928 164 GYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALS 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 241 TILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNgQKRDWMSTWT 320
Cdd:PRK09928 244 VIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFD-RPTEWMNNWT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 321 LYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFG----VLGIETGKKHPELFKMSPETQLFGVF 396
Cdd:PRK09928 323 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGnsalYEIIHGNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 397 HHIPMGIVLSIIALLLIASFFITSADSATFVLGMQTT-FGSLN--PSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAI 473
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSkLKDINsdAPNWLRVFWSVAIGLLTLGMLMTNG------ISAL 476
                        490       500
                 ....*....|....*....|....
gi 488383788 474 QSAAIISAFPFSFVVIMMMISFYK 497
Cdd:PRK09928 477 QNTTVIMGLPFSFVIFFVMAGLYK 500
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-504 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 632.57  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   1 MNSSSHEKKNKKFS-SVFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKL 79
Cdd:COG1292    1 MSDKNKEKFKKKIDpPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  80 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPP-TADPKTTAAYTEALRSTFFHWGFHAWAIYGVVAL 158
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 159 ALAYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIV 238
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 239 IVTILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNGqkRDWMST 318
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 319 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVLGIETGKKHP----ELFKMSPETQLFG 394
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 395 VFHHIPMGIVLSIIALLLIASFFITSADSATFVLGMQTTFGSLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQ 474
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 488383788 475 SAAIISAFPFSFVVIMMMISFYKDANQERK 504
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
16-502 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 599.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   16 VFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISW 95
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   96 FAMLFSAGMGIGLVFYGAAEPMADFAA-PPTADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALALAYAQFRKGEPGLIS 174
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  175 RTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSK 254
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  255 GIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALnGQKRDWMSTWTLYYWGWWLSWSPFV 334
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  335 GVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVLGIETGKKHP----ELFKMSPETQLFGVFHHIPMGIVLSIIAL 410
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  411 LLIASFFITSADSATFVLGMQTTFGSLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQSAAIISAFPFSFVVIM 490
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 488383788  491 MMISFYKDANQE 502
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
54-502 5.38e-161

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 466.06  E-value: 5.38e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   54 GWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPPT-ADPKTTA 132
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFgAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  133 AYTEALRSTFFHWGFHAWAIYGVVALALAYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMG 212
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  213 ALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTG 292
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  293 SLLNTFLFNSLDTAALNGqKRDWMSTWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFGVL 372
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDG-KGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  373 GIETGKKH-----PELFKMSPETQLFGVFHHIPMGIVLSIIALLLIASFFITSADSATFVLG-MQTTFGSLN--PSIMVK 444
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLGeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488383788  445 VTWGVAQALIAFVLLLAGGgdgskALNAIQSAAIISAFPFSFVVIMMMISFYKDANQE 502
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-497 1.03e-124

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 380.97  E-value: 1.03e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788   1 MNSSSHEKKNKKFSSVFIYSSIIVAIVVIIGAIWPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLK 80
Cdd:PRK09928   4 TDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  81 LGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMADFAAPPTADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALAL 160
Cdd:PRK09928  84 LGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMAL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 161 AYAQFRKGEPGLISRTLRPILGNKVEGPIGTLIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIV 240
Cdd:PRK09928 164 GYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALS 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 241 TILFIASAWSGLSKGIQYLSNLNISLGAILMIITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNgQKRDWMSTWT 320
Cdd:PRK09928 244 VIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFD-RPTEWMNNWT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 321 LYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPALVSFVWFSVFG----VLGIETGKKHPELFKMSPETQLFGVF 396
Cdd:PRK09928 323 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGnsalYEIIHGNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 397 HHIPMGIVLSIIALLLIASFFITSADSATFVLGMQTT-FGSLN--PSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAI 473
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSkLKDINsdAPNWLRVFWSVAIGLLTLGMLMTNG------ISAL 476
                        490       500
                 ....*....|....*....|....
gi 488383788 474 QSAAIISAFPFSFVVIMMMISFYK 497
Cdd:PRK09928 477 QNTTVIMGLPFSFVIFFVMAGLYK 500
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
35-499 1.09e-68

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 229.62  E-value: 1.09e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  35 PEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGkpNDKPEFNTISWFAMLFSAGMGIGLVFYGAA 114
Cdd:PRK03356  33 LDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLG--DEKPEFSTASWIFMMFASCTSAAVLFWGSI 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 115 EPMADFAAPP-TADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALALAYAQF-RKGEPGLISRTLRPILGNK-VEGPIGT 191
Cdd:PRK03356 111 EIYYYISTPPfGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFvRKMDVIRPSSTLVPLVGEKhAKGLFGT 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 192 LIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSKGIQYLSNLNISLGAILM 271
Cdd:PRK03356 191 IVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLML 270
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 272 IITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNgqKRDWMSTWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFI 351
Cdd:PRK03356 271 GWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIG--KGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELC 348
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 352 SGVLLvpALVSFVWFsVFGVLGIETGKKHPE-LFKMSPETQLFGVFHHI-------PMGIVLSIIALLLIASFFITSADS 423
Cdd:PRK03356 349 FGMVL--GLTASTWI-LWTVLGSNTLLLMDKnIINIPNLIEQYGVARAIietwaalPLSTATMWGFFILCFIATVTLINA 425
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488383788 424 ATFVLGMQTTFGSL---NPSIMVKVTWGVAQALIAFVLLLAGGgdgskaLNAIQSAAIISAFPFSFVVIMMMISFYKDA 499
Cdd:PRK03356 426 CSYTLAMSTCREVRdgeEPPLLVRIGWSILVGIIGIVLLALGG------LKPIQTAIIAGGCPLFFVNIMVTLSFIKDA 498
PRK09950 PRK09950
putative transporter; Provisional
34-502 3.82e-61

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 209.65  E-value: 3.82e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788  34 WPEKFDYITNNAKMWITDKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKpnDKPEFNTISWFAMLFSAGMGIGLVFYGA 113
Cdd:PRK09950  30 FPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGE--GKPEYSTLSWLFMFICAGLGSSTLYWGV 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 114 AEPMADFAAPP-TADPKTTAAYTEALRSTFFHWGFHAWAIYGVVALALAYAQFRKGEPGL-ISRTLRPILGNKVEGPIGT 191
Cdd:PRK09950 108 MEWAYYYQTPGlNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYHFHVRKNKGLsLSGIIAAITGVKPQGPWGR 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 192 LIDVLSVFATLVGVAVSLGMGALQINGGLNYLFNVPNNTLVQGIIIVIVTILFIASAWSGLSKGIQYLSNLnISLGAILM 271
Cdd:PRK09950 188 LVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSSYIGIDNGLQRLSKM-VGWGAFLF 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 272 -IITLIIGPTVLILNMMTSSTGSLLNTFLFNSLDTAALNGQKrdWMSTWTLYYWGWWLSWSPFVGVFIARVSKGRSIREF 350
Cdd:PRK09950 267 aLLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGDGS--FTRNWTVFYWLWWISYTPGVAMFVTRVSRGRKIKEV 344
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 351 ISGVLLVPALvsFVWFsVFGVLG-------IETGKKHPELFK-MSPETQLFGVFHHIPMGIVLSIIALLLIASFFITSAD 422
Cdd:PRK09950 345 IWGLILGSSV--GCWF-FFGVLEsyaihqfINGVINVPQILNtLGGETAVQQLLSSLPAGKLFLAAYLGIMIIFLASHMD 421
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488383788 423 SATFVLGMQTTFG---SLNPSIMVKVTWGVAQALIAFVLLLAGGgdgskALNAIQSAAIISAFPFSFVVIMMMISFYKDA 499
Cdd:PRK09950 422 AVAYTMAATSTRNlreGDDPDRGLRLFWCVVITLIPLSILFTGA-----SLDTMKTTVVLTALPFLVILLIKVYGFIRWL 496

                 ...
gi 488383788 500 NQE 502
Cdd:PRK09950 497 KQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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