|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK13906 |
UDP-N-acetylmuramate dehydrogenase; |
1-306 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184386 [Multi-domain] Cd Length: 307 Bit Score: 610.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 1 MNKNDILRGLESILPKDIIKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIR 80
Cdd:PRK13906 1 MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 81 GIVLSLLSLNHIETSDDAIIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEK 160
Cdd:PRK13906 81 GIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 161 GDLLKLTTAELELDYRNSVVQQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLI 240
Cdd:PRK13906 161 GSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLI 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488388214 241 QDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIGEHPTD 306
Cdd:PRK13906 241 QDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKE 306
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
23-300 |
3.04e-143 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 404.40 E-value: 3.04e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 23 EPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLNHIETSDDAII-A 101
Cdd:COG0812 1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDGFDGLVIRLGRLKGIEVDDGVLVtA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 102 GSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKLTTAELELDYRNSVVQ 181
Cdd:COG0812 81 GAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLDRTGEVRTLSAEECGFGYRDSIFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 182 QKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAG 261
Cdd:COG0812 161 RERYIILSVTFRLKKGDPAEIAAVMDAVLAIRRSKQPLELPSAGSFFKNPPGDSAGWLIEQAGLKGYRIGGAQVSEKHAN 240
|
250 260 270
....*....|....*....|....*....|....*....
gi 488388214 262 FMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRII 300
Cdd:COG0812 241 FLVNRGGATAADVLALIEEVQARVKEKFGVELEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
25-301 |
5.24e-79 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 241.59 E-value: 5.24e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 25 LKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLN-HIETSDDAIIAGS 103
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIdIEDDEGEYVHVGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 104 GAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKLTTAELELDYRNSVVQQK 183
Cdd:TIGR00179 81 GENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKTEWLTNEQLGFGYRTSIFQHK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 184 HL-VVLEAAFTLEPG---KLDE--IQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVST 257
Cdd:TIGR00179 161 YVgLVLKAEFQLTLGfgtRLDPetITAQQVFNKVCRMRTSHYPDPNAGSFFKNPSPNHAGRLIEECGLKGYQIGGAAVSK 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 488388214 258 KHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIG 301
Cdd:TIGR00179 241 QHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEPEVKIIG 284
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
202-300 |
4.12e-54 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 171.38 E-value: 4.12e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 202 IQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHV 281
Cdd:pfam02873 1 IRAAMLELRRRRLAKQPLDPPSAGSFFKNPVGHSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNTGGATAADVLALIEEV 80
|
90
....*....|....*....
gi 488388214 282 QKTVKEKFDVELNTEVRII 300
Cdd:pfam02873 81 RERVKEKFGVELEPEVRII 99
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK13906 |
UDP-N-acetylmuramate dehydrogenase; |
1-306 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184386 [Multi-domain] Cd Length: 307 Bit Score: 610.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 1 MNKNDILRGLESILPKDIIKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIR 80
Cdd:PRK13906 1 MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 81 GIVLSLLSLNHIETSDDAIIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEK 160
Cdd:PRK13906 81 GIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 161 GDLLKLTTAELELDYRNSVVQQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLI 240
Cdd:PRK13906 161 GSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLI 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488388214 241 QDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIGEHPTD 306
Cdd:PRK13906 241 QDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKE 306
|
|
| murB |
PRK13905 |
UDP-N-acetylmuramate dehydrogenase; |
10-302 |
1.41e-160 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237553 [Multi-domain] Cd Length: 298 Bit Score: 449.18 E-value: 1.41e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 10 LESILP--KDIIKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSL- 86
Cdd:PRK13905 2 LKELLPalRGRLLENEPLARYTSFRVGGPADYLVEPADIEDLQEFLKLLKENNIPVTVLGNGSNLLVRDGGIRGVVIRLg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 87 LSLNHIETSDDAIIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKL 166
Cdd:PRK13905 82 KGLNEIEVEGNRITAGAGAPLIKLARFAAEAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVLDRDGEIKTL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 167 TTAELELDYRNSVVQQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQ 246
Cdd:PRK13905 162 SNEELGFGYRHSALQEEGLIVLSATFQLEPGDKEEIKARMDELLARREATQPLEYPSAGSVFKNPPGHFAGKLIEEAGLK 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 488388214 247 GYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIGE 302
Cdd:PRK13905 242 GYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWEVRIIGE 297
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
23-300 |
3.04e-143 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 404.40 E-value: 3.04e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 23 EPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLNHIETSDDAII-A 101
Cdd:COG0812 1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDGFDGLVIRLGRLKGIEVDDGVLVtA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 102 GSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKLTTAELELDYRNSVVQ 181
Cdd:COG0812 81 GAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLDRTGEVRTLSAEECGFGYRDSIFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 182 QKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAG 261
Cdd:COG0812 161 RERYIILSVTFRLKKGDPAEIAAVMDAVLAIRRSKQPLELPSAGSFFKNPPGDSAGWLIEQAGLKGYRIGGAQVSEKHAN 240
|
250 260 270
....*....|....*....|....*....|....*....
gi 488388214 262 FMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRII 300
Cdd:COG0812 241 FLVNRGGATAADVLALIEEVQARVKEKFGVELEPEVRII 279
|
|
| PRK12436 |
PRK12436 |
UDP-N-acetylmuramate dehydrogenase; |
1-302 |
1.57e-141 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 171497 [Multi-domain] Cd Length: 305 Bit Score: 401.31 E-value: 1.57e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 1 MNKNDILRGLESILPKDIIKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIR 80
Cdd:PRK12436 1 MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 81 GIVLSLLSLNHIETSDDAIIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEK 160
Cdd:PRK12436 81 GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 161 GDLLKLTTAELELDYRNSVVQQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLI 240
Cdd:PRK12436 161 GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGVYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488388214 241 QDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIGE 302
Cdd:PRK12436 241 QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGE 302
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
25-301 |
5.24e-79 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 241.59 E-value: 5.24e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 25 LKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLN-HIETSDDAIIAGS 103
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIdIEDDEGEYVHVGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 104 GAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKLTTAELELDYRNSVVQQK 183
Cdd:TIGR00179 81 GENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKTEWLTNEQLGFGYRTSIFQHK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 184 HL-VVLEAAFTLEPG---KLDE--IQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVST 257
Cdd:TIGR00179 161 YVgLVLKAEFQLTLGfgtRLDPetITAQQVFNKVCRMRTSHYPDPNAGSFFKNPSPNHAGRLIEECGLKGYQIGGAAVSK 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 488388214 258 KHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIG 301
Cdd:TIGR00179 241 QHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEPEVKIIG 284
|
|
| PRK14652 |
PRK14652 |
UDP-N-acetylmuramate dehydrogenase; |
19-302 |
4.10e-66 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237777 [Multi-domain] Cd Length: 302 Bit Score: 209.34 E-value: 4.10e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 19 IKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLNHIETSDDA 98
Cdd:PRK14652 18 VLRDAPLAPRTAVRVGGPADLLVRPADPDALSALLRAVRELGVPLSILGGGANTLVADAGVRGVVLRLPQDFPGESTDGG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 99 -IIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDyALCVNEKGDLLKLTTAELELDYRN 177
Cdd:PRK14652 98 rLVLGAGAPISRLPARAHAHGLVGMEFLAGIPGTLGGAVAMNAGTKLGEMKDVVT-AVELATADGAGFVPAAALGYAYRT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 178 SVVQQKHlVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVST 257
Cdd:PRK14652 177 CRLPPGA-VITRVEVRLRPGDVAASEALMRADRERRRRTQPLDRPTFGSTFTNPPGDYAGRLVEAVGLKGHRVGGAIWSP 255
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 488388214 258 KHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIGE 302
Cdd:PRK14652 256 VHANFVTNLGGATARDVLALVRLARARVKERFGIALETEVRLLGE 300
|
|
| PRK14653 |
PRK14653 |
UDP-N-acetylmuramate dehydrogenase; |
21-299 |
1.08e-63 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237778 [Multi-domain] Cd Length: 297 Bit Score: 202.76 E-value: 1.08e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 21 VDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHEnSIPVTYLGNGSNIIIREGGIRGIVLSLLSLNHIETSDDAII 100
Cdd:PRK14653 18 INEEMKCHVSFKIGGPVPLFAIPNSTNGFIETINLLKE-GIEVKILGNGTNVLPKDEPMDFVVVSTERLDDIFVDNDKII 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 101 AGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKgDLLKLTTAELELDYRNSVV 180
Cdd:PRK14653 97 CESGLSLKKLCLVAAKNGLSGFENAYGIPGSVGGAVYMNAGAYGWETAENIVEVVAYDGK-KIIRLGKNEIKFSYRNSIF 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 181 -QQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRP-PGHFAGKLIQDSNLQGYRIGGVEVSTK 258
Cdd:PRK14653 176 kEEKDLIILRVTFKLKKGNKNEIYNLMLETMKKRVEKQPLEFPSAGSVFKRPrKDFYVGSAIEKLGLKGFSIGGAQISEK 255
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 488388214 259 HAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRI 299
Cdd:PRK14653 256 HAGFIINYNNAKAEDVLKLIEYVKDKIYENYNVELETEIEI 296
|
|
| PRK14649 |
PRK14649 |
UDP-N-acetylmuramate dehydrogenase; |
22-301 |
9.96e-63 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173112 [Multi-domain] Cd Length: 295 Bit Score: 200.45 E-value: 9.96e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 22 DEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLS--LNHIETSDDA- 98
Cdd:PRK14649 6 NEPLAPYTSWRIGGPARYFVEPTTPDEAIAAAAWAEQRQLPLFWLGGGSNLLVRDEGFDGLVARYRGqrWELHEHGDTAe 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 99 IIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDLLKLTTAELELDYRNS 178
Cdd:PRK14649 86 VWVEAGAPMAGTARRLAAQGWAGLEWAEGLPGTIGGAIYGNAGCYGGDTATVLIRAWLLLNGSECVEWSVHDFAYGYRTS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 179 VVQQ--------KHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEfPSCGSVFQRPPGHFAGKLIQDSNLQGYRI 250
Cdd:PRK14649 166 VLKQlradgitwRPPLVLAARFRLHRDDPTALAARMEAIAAERKQKTPAG-SSCGSVFKNPPGDSAGRLIEAAGLKGTRI 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 488388214 251 GGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIG 301
Cdd:PRK14649 245 GDAEIATRHANYIINLGGARAADILRLIDLARTRVLAQFGIELELEVRIIG 295
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
202-300 |
4.12e-54 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 171.38 E-value: 4.12e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 202 IQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHV 281
Cdd:pfam02873 1 IRAAMLELRRRRLAKQPLDPPSAGSFFKNPVGHSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNTGGATAADVLALIEEV 80
|
90
....*....|....*....
gi 488388214 282 QKTVKEKFDVELNTEVRII 300
Cdd:pfam02873 81 RERVKEKFGVELEPEVRII 99
|
|
| PRK14650 |
PRK14650 |
UDP-N-acetylmuramate dehydrogenase; |
6-301 |
5.67e-45 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173113 [Multi-domain] Cd Length: 302 Bit Score: 154.62 E-value: 5.67e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 6 ILRGLESILPKDIIKVD-EPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGG-IRGIV 83
Cdd:PRK14650 1 MLKNINNFLKKINIKPQtKNLANYTTYKIGGISKLFLTPKTIKDAEHIFKAAIEEKIKIFILGGGSNILINDEEeIDFPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 84 LSLLSLNHIETSDDAIIAGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGDL 163
Cdd:PRK14650 81 IYTGHLNKIEIHDNQIVAECGTNFEDLCKFALQNELSGLEFIYGLPGTLGGAIWMNARCFGNEISEILDKITFIDEKGKT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 164 LKLTTAELELDYRNSVVQQKHLVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGSVFQRPPGHF--AGKLIQ 241
Cdd:PRK14650 161 ICKKFKKEEFKYKISPFQNKNTFILKATLNLKKGNKKHIEEIMKQNKQIRINKGHYLFPSSGSTFKNNKAFLkpTGQIIE 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 242 DSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRIIG 301
Cdd:PRK14650 241 ECKLKGLSIGGATVSHYHGNFIININNATSKDIKTLIEKVKTEVQIKTGFLLEEEVLYIG 300
|
|
| murB |
PRK13904 |
UDP-N-acetylmuramate dehydrogenase; |
112-300 |
2.42e-42 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184384 [Multi-domain] Cd Length: 257 Bit Score: 146.61 E-value: 2.42e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 112 NVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDyALCVNeKGDLLKlttAELELDYRNSVVQQkhlVVLEAA 191
Cdd:PRK13904 82 NYAKKNNLGGFEFLGKLPGTLGGLVKMNAGLKEYEISNNLE-SICTN-GGWIEK---EDIGFGYRSSGING---VILEAR 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 192 FTLEPGKLDEIQakmDDLTERRESkQPLEfPSCGSVFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAGFMVNVDNGTA 271
Cdd:PRK13904 154 FKKTHGFDEELL---EAFKSMRKN-QPKG-PSFGSCFKNPKGDYAGRLIEAVGLKGYCKGGAGFSEEHANFLVNLGGATF 228
|
170 180
....*....|....*....|....*....
gi 488388214 272 TDYEALIHHVQKTVKEKFDVELNTEVRII 300
Cdd:PRK13904 229 EDALDLIELAKKRVLEEFGINLEEEVIIL 257
|
|
| PRK14651 |
PRK14651 |
UDP-N-acetylmuramate dehydrogenase; |
24-304 |
4.69e-38 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237776 [Multi-domain] Cd Length: 273 Bit Score: 135.72 E-value: 4.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 24 PLKRYTYTETGGKADFYLSPTKNEEVQAIvkfahenSIPVTYLGNGSNIIIREGGIRGIVLSLLSlnHIETSDDAIIAGS 103
Cdd:PRK14651 8 PLARYTTLGVGGPAELWTVETHEQLAEAT-------EAPYRVLGGGSNLLVSDAGVPERVIRLGG--EFAEWDLDGWVGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 104 GAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCVNEKGdLLKLTTAELELDYRNSVVQQK 183
Cdd:PRK14651 79 GVPLPGLVRRAARLGLSGLEGLVGIPAQVGGAVKMNAGTRFGEMADALHTVEIVHDGG-FHQYSPDELGFGYRHSGLPPG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 184 HlVVLEAAFTLEPGKLDEIQAKMDDLTERRESKQPLEFPSCGsvFQRPPGHFAGKLIQDSNLQGYRIGGVEVSTKHAGFM 263
Cdd:PRK14651 158 H-VVTRVRLKLRPSTPEAVLAKMALVDAARKGQPKKKSAGCA--FKNPPGDSAGRLIDEAGLKGTRVGDAMISPEHGNFI 234
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 488388214 264 VNVDNGTATDYEALIHHVQktvkEKFDVELNTEVRIIGEHP 304
Cdd:PRK14651 235 VNLGGATAADVHALLRRVR----ARVGLPLELEWELWPEQL 271
|
|
| PRK14648 |
PRK14648 |
UDP-N-acetylmuramate dehydrogenase; |
13-302 |
5.27e-35 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173111 [Multi-domain] Cd Length: 354 Bit Score: 129.84 E-value: 5.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 13 ILPKDIIKVDEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLN-- 90
Cdd:PRK14648 6 IRARRITRRNVPLAERCSFRIGGAAQFWAEPRSCTQLRALIEEAQRARIPLSLIGGGSNVLIADEGVPGLMLSLRRFRsl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 91 HIETSDDAII---AGSGAAIIDVSNVARDHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCIDYALCV---------- 157
Cdd:PRK14648 86 HTQTQRDGSVlvhAGAGLPVAALLAFCAHHALRGLETFAGLPGSVGGAAYMNARCYGRAIADCFHSARTLvlhpvrsrak 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 158 ----------NEKGDLLKLTTAEL-------------ELDYRNSVVQQKHLVVLEAA--------FTLEPGKLDEIQAKM 206
Cdd:PRK14648 166 elpevrknaqDKRGECLGLDGGPFtcssfqtvfaragDWGYKRSPFQSPHGVELHAGrrlilslcVRLTPGNPAQIRKHM 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 207 DDLTERRESKQPLEFPSCGSVFQRPP--GHFAGKLIQDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKT 284
Cdd:PRK14648 246 QEKIADRISKGQFRFPSAGSAFKNNPafGKPSGILIEEAGLRGTSCGAAQVAPWHGNLIINTGNATAHQVRTLLRVVRQR 325
|
330
....*....|....*...
gi 488388214 285 VKEKFDVELNTEVRIIGE 302
Cdd:PRK14648 326 VFETHGVWLEREIIFSGE 343
|
|
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
36-300 |
4.17e-30 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 116.01 E-value: 4.17e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 36 KADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGgIRGIVL--SLLSLNHIETSDDAII--AGSGAAIIDVS 111
Cdd:PRK00046 20 RARHLVEAESEEQLLEALADARAAGLPVLVLGGGSNVLFTED-FDGTVLlnRIKGIEVLSEDDDAWYlhVGAGENWHDLV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 112 NVARDHVLTGLE-FACgIPGSIGGAVFMNAGAYGGEVKDCIDYALCVN-EKGDLLKLTTAELELDYRNSV----VQQKHL 185
Cdd:PRK00046 99 LWTLQQGMPGLEnLAL-IPGTVGAAPIQNIGAYGVELKDVCDYVEALDlATGEFVRLSAAECRFGYRDSIfkheYPDRYA 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 186 VV-------LEAAFTLEPGKLDEIQAkmDDLTER---------RESK--QPLEFPSCGSVFQRP--------------PG 233
Cdd:PRK00046 178 ITavgfrlpKQWQPVLDYGDLARLDP--DTVTAQdvfdavcaiRRSKlpDPKVLGNAGSFFKNPvvsaeqfeallaqyPD 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488388214 234 --HF----------AGKLIQDSNLQGYRIGGVEVSTKHAGFMVNVDNGTATDYEALIHHVQKTVKEKFDVELNTEVRII 300
Cdd:PRK00046 256 ipHYpqadgsvklaAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLALARHIQQDVREKFGVELEPEPRFI 334
|
|
| FAD_binding_4 |
pfam01565 |
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ... |
37-167 |
6.96e-27 |
|
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 426326 [Multi-domain] Cd Length: 139 Bit Score: 102.28 E-value: 6.96e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 37 ADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLNHIETSDDA---IIAGSGAAIIDVSNV 113
Cdd:pfam01565 1 PAAVVLPESEEEVAAIVRLANENGLPVLPRGGGSSLLGGAVQTGGIVLDLSRLNGILEIDPEdgtATVEAGVTLGDLVRA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 488388214 114 ARDH-VLTGLEFACGIPGSIGGAVFMNAGAYGGE----VKDCIDYALCVNEKGDLLKLT 167
Cdd:pfam01565 81 LAAKgLLLGLDPGSGIPGTVGGAIATNAGGYGSEkyglTRDNVLGLEVVLADGEVVRLG 139
|
|
| murB |
PRK13903 |
UDP-N-acetylmuramate dehydrogenase; |
22-301 |
8.29e-26 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237552 [Multi-domain] Cd Length: 363 Bit Score: 105.04 E-value: 8.29e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 22 DEPLKRYTYTETGGKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIIIREGGIRGIVLSLLSLN-HIETSDDAII 100
Cdd:PRK13903 18 DVPLAPLTTLRVGGPARRLVTCTSTEELVAAVRELDAAGEPLLVLGGGSNLVIADDGFDGTVVRVATRGvTVDCGGGLVR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 101 AGSGAAIIDVsnVAR--DHVLTGLEFACGIPGSIGGAVFMNAGAYGGEVKDCI------DYALcvnekGDLLKLTTAELE 172
Cdd:PRK13903 98 AEAGAVWDDV--VARtvEAGLGGLECLSGIPGSAGATPVQNVGAYGQEVSDTItrvrllDRRT-----GEVRWVPAADLG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 173 LDYRNSVVQQK-HLVVLEAAFTLEPGKLD------EIQAKMD-------DLTERRE-------SKQPLEFP------SCG 225
Cdd:PRK13903 171 FGYRTSVLKHSdRAVVLEVEFQLDPSGLSaplrygELARALGvepgervPPAAVREavlalraGKGMVLDPadhdtwSAG 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 226 SVFQRP----------------------------PGHF---AGKLIQDSNL-QGYRIGG--VEVSTKHAGFMVNVDNGTA 271
Cdd:PRK13903 251 SFFTNPvvspavaerlaarvaerlgdpvprypagDGGVklsAAWLIERAGFgKGYPGGGapARLSTKHTLALTNRGGATT 330
|
330 340 350
....*....|....*....|....*....|
gi 488388214 272 TDYEALIHHVQKTVKEKFDVELNTEVRIIG 301
Cdd:PRK13903 331 ADLVALAREVRDGVRDAFGVTLVPEPVLVG 360
|
|
| GlcD |
COG0277 |
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion]; |
1-144 |
4.39e-13 |
|
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];
Pssm-ID: 440046 [Multi-domain] Cd Length: 462 Bit Score: 69.15 E-value: 4.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 1 MNKNDILRGLESILPKDIIKVDEPLKRYTYTETG---GKADFYLSPTKNEEVQAIVKFAHENSIPVTYLGNGSNIiirEG 77
Cdd:COG0277 1 MLTAALLAALRAILAGRVLTDPADRAAYARDGNSlyrGRPDAVVRPRSTEDVAAVVRLAAEHGVPVVPRGGGTGL---AG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 78 GI----RGIVLSLLSLNHIETSDDA---IIAGSGAAIIDVSNVARDHvltGLEFACGiPGS-----IGGAVFMNAG---- 141
Cdd:COG0277 78 GAvpldGGVVLDLSRMNRILEVDPEdrtATVEAGVTLADLNAALAPH---GLFFPPD-PSSqgtatIGGNIATNAGgprs 153
|
....
gi 488388214 142 -AYG 144
Cdd:COG0277 154 lKYG 157
|
|
| PRK11230 |
PRK11230 |
glycolate oxidase subunit GlcD; Provisional |
2-172 |
3.59e-05 |
|
glycolate oxidase subunit GlcD; Provisional
Pssm-ID: 183043 [Multi-domain] Cd Length: 499 Bit Score: 45.15 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 2 NKNDILRGLESILPK-DIIKVDEPLKRYtytETGGKADFYLSPT------KNEEVQAIVKFAHENSIPVTYLGNGSNIii 74
Cdd:PRK11230 17 DRTSLLMALREHLPGlEILHTDEELIPY---ECDGLSAYRTRPLlvvlpkQMEQVQALLAVCHRLRVPVVARGAGTGL-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488388214 75 rEGGI----RGIVLSLLSLNHI-ETSDDAIIA--GSGAAIIDVSNVARDHvltGLEFA----CGIPGSIGGAVFMNAGAY 143
Cdd:PRK11230 92 -SGGAlpleKGVLLVMARFNRIlDINPVGRRArvQPGVRNLAISQAAAPH---GLYYApdpsSQIACSIGGNVAENAGGV 167
|
170 180
....*....|....*....|....*....
gi 488388214 144 ggevkDCIDYALCVNekgDLLKLTTAELE 172
Cdd:PRK11230 168 -----HCLKYGLTVH---NLLKVEILTLD 188
|
|
| |
