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Conserved domains on  [gi|488391473|ref|WP_002460858|]
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FAD-dependent monooxygenase [Staphylococcus lugdunensis]

Protein Classification

FAD-dependent monooxygenase( domain architecture ID 1001323)

FAD-dependent monooxygenase catalyzes the incorporation of one hydroxyl group into target substrates in various metabolic pathways, such as Streptomyces rimosus 6-methylpretetramide 4-monooxygenase that catalyzes the double hydroxylation of 6-methylpretetramide to yield 4-keto-anhydrotetracycline, via the insertion of oxygen atoms at the C-12a and C-4 positions of 6-pretetramid

CATH:  3.50.50.60
EC:  1.14.13.-
Gene Ontology:  GO:0071949|GO:0016709
PubMed:  30945211|31869345|25704928
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06184 super family cl35443
hypothetical protein; Provisional
 4-477 2.51e-77

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PRK06184:

Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 251.06  E-value: 2.51e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDKRLVG 83
Cdd:PRK06184   5 DVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLYPPMRIYRDDGSVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  84 --KLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQPNGEEvTETFNYICGC 161
Cdd:PRK06184  85 esDMFAHLEPTPDEPYPLPLMVPQWRTERILRERLAELGHRVEFGCELVGFEQDADGVTARVAGPAGEE-TVRARYLVGA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 162 DGASSTVRKRLDIGFPGGTYTQL-FYVADVEtntqLDGAS-----MGFHGNHFCVGF-PIRTTEQLRLIGIIPEEvktnG 234
Cdd:PRK06184 164 DGGRSFVRKALGIGFPGETLGIDrMLVADVS----LTGLDrdawhQWPDGDMGMIALcPLPGTDLFQIQAPLPPG----G 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 235 EPPES---FKPLIPFAENILPIHIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKL 311
Cdd:PRK06184 236 EPDLSadgLTALLAERTGRTDIRLHSVTWASAFRMNARLADRYRVGRVFLAGDAAHVHPPAGGQGLNTSVQDAYNLGWKL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 312 SNVIQGkADKSILDTYEPERIEFAKKLVNTTDTGFKFMANSQVVKDwiipyifptllhldilkkklyKTISQTAIHYKHS 391
Cdd:PRK06184 316 AAVLAG-APEALLDTYEEERRPVAAAVLGLSTELLDAIKRGDMRRG---------------------RDVQQLDLGYRGS 373

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 392 DLSI---GNYGNIAGGDRLPWIHIDSIDN-----FEPLKSRTWQIHIYGKLTQELKQfayDSQLPIYHIpwVTQMSQKDI 463
Cdd:PRK06184 374 SLAVdgpERTGGLRAGDRAPDAPLLGAAGqptrlFDLFRGPHWTLLAFGAGAAAILA---RRGLRIHRV--GDAAEGGDL 448

                        490       500
                 ....*....|....*....|....*..
gi 488391473 464 QRDA-------------VFLVRPDGYI 477
Cdd:PRK06184 449 VDDAghfrdaygltggtLVLVRPDGYV 475
 
Name Accession Description Interval E-value
PRK06184 PRK06184
hypothetical protein; Provisional
 4-477 2.51e-77

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 251.06  E-value: 2.51e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDKRLVG 83
Cdd:PRK06184   5 DVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLYPPMRIYRDDGSVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  84 --KLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQPNGEEvTETFNYICGC 161
Cdd:PRK06184  85 esDMFAHLEPTPDEPYPLPLMVPQWRTERILRERLAELGHRVEFGCELVGFEQDADGVTARVAGPAGEE-TVRARYLVGA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 162 DGASSTVRKRLDIGFPGGTYTQL-FYVADVEtntqLDGAS-----MGFHGNHFCVGF-PIRTTEQLRLIGIIPEEvktnG 234
Cdd:PRK06184 164 DGGRSFVRKALGIGFPGETLGIDrMLVADVS----LTGLDrdawhQWPDGDMGMIALcPLPGTDLFQIQAPLPPG----G 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 235 EPPES---FKPLIPFAENILPIHIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKL 311
Cdd:PRK06184 236 EPDLSadgLTALLAERTGRTDIRLHSVTWASAFRMNARLADRYRVGRVFLAGDAAHVHPPAGGQGLNTSVQDAYNLGWKL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 312 SNVIQGkADKSILDTYEPERIEFAKKLVNTTDTGFKFMANSQVVKDwiipyifptllhldilkkklyKTISQTAIHYKHS 391
Cdd:PRK06184 316 AAVLAG-APEALLDTYEEERRPVAAAVLGLSTELLDAIKRGDMRRG---------------------RDVQQLDLGYRGS 373

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 392 DLSI---GNYGNIAGGDRLPWIHIDSIDN-----FEPLKSRTWQIHIYGKLTQELKQfayDSQLPIYHIpwVTQMSQKDI 463
Cdd:PRK06184 374 SLAVdgpERTGGLRAGDRAPDAPLLGAAGqptrlFDLFRGPHWTLLAFGAGAAAILA---RRGLRIHRV--GDAAEGGDL 448

                        490       500
                 ....*....|....*....|....*..
gi 488391473 464 QRDA-------------VFLVRPDGYI 477
Cdd:PRK06184 449 VDDAghfrdaygltggtLVLVRPDGYV 475
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 4-339 1.13e-71

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 231.45  E-value: 1.13e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIP--IQHFNVYKDKRl 81
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPheGMGLAFYNTRR- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   82 VGKLpiakkgKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQP-NGEEVTETFNYICG 160
Cdd:pfam01494  82 RADL------DFLTSPPRVTVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDGVTAVVRDRrDGEEYTVRAKYLVG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  161 CDGASSTVRKRLDIGFPGGTYTQ------LFYVADVETNTQLDGASMGFHGNHFcVGFPIRTTEQL----RLIGIIPEEV 230
Cdd:pfam01494 156 CDGGRSPVRKTLGIEFEGFEGVPfgsldvLFDAPDLSDPVERAFVHYLIYAPHS-RGFMVGPWRSAgrerYYVQVPWDEE 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  231 KTNGEPPES---FKPLIP--FAENILPIhikNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAF 305
Cdd:pfam01494 235 VEERPEEFTdeeLKQRLRsiVGIDLALV---EILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAF 311

                         330       340       350
                  ....*....|....*....|....*....|....
gi 488391473  306 NLAWKLSNVIQGKADKSILDTYEPERIEFAKKLV 339
Cdd:pfam01494 312 NLAWKLAAVLRGQAGESLLDTYSAERLPVAWAVV 345
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-352 1.82e-69

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 224.82  E-value: 1.82e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDK- 79
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDGSd 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  80 -RLVGKLPIAKKGkdvspYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQqpNGEEVteTFNYI 158
Cdd:COG0654   82 gRVLARFDAAETG-----LPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADGVTVTLA--DGRTL--RADLV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 159 CGCDGASSTVRKRLDIGFPGGTYTQLFYVADVEtntqldgasmgfhgnhfcvgfpirtTEQLRLIGIIPEEVKtngeppe 238
Cdd:COG0654  153 VGADGARSAVRRLLGIGFTGRDYPQRALWAGVR-------------------------TELRARLAAAGPRLG------- 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 239 sfkplipfaenilpiHIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGK 318
Cdd:COG0654  201 ---------------ELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGR 265

                        330       340       350
                 ....*....|....*....|....*....|....
gi 488391473 319 ADKSILDTYEPERIEFAKKLVNTTDTGFKFMANS 352
Cdd:COG0654  266 DDEAALARYERERRPRAARVQRAADALGRLFHPD 299
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 4-331 4.51e-12

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 67.61  E-value: 4.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNkgPGTASRAMVVQSRVL-------EFYRQYDFDDKIVEAGI-PIQHFNV 75
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSGLKVALIEAT--PLPAPADPGFDNRVSalsaasiRLLEKLGVWDKIEPARAqPIRDIHV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   76 YkDKRLVGKLPIAKKGKDVSPYPYVL-------TLPQDIHEQ--------ILVEELEKVGGQVCwehelISFDDNETFIS 140
Cdd:TIGR01988  79 S-DGGSFGALRFDADEIGLEALGYVVenrvlqqALWERLQELpnvtllcpARVVELPRHSDHVE-----LTLDDGQQLRA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  141 atfqqpngeevtetfNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQLDGASMGFHgnhfcvgFPIRTTEQL 220
Cdd:TIGR01988 153 ---------------RLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERF-------TPTGPLALL 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  221 ----RLIGII----PEEVKT-NGEPPESFKPLI--PFAENILPIHIkninwySSYRSHH----RVAEHFRVNRAFICGDA 285
Cdd:TIGR01988 211 plpdNRSSLVwtlpPEEAERlLALSDEEFLAELqrAFGSRLGAITL------VGERHAFplslTHAKRYVAPRLALIGDA 284

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 488391473  286 GH-IHsPAGGQGMNTGISDAFNLAWKLSNVI-QGK--ADKSILDTYEPER 331
Cdd:TIGR01988 285 AHtIH-PLAGQGLNLGLRDVAALAEVLEDARrRGEdiGSLRVLQRYERRR 333
 
Name Accession Description Interval E-value
PRK06184 PRK06184
hypothetical protein; Provisional
 4-477 2.51e-77

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 251.06  E-value: 2.51e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDKRLVG 83
Cdd:PRK06184   5 DVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLYPPMRIYRDDGSVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  84 --KLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQPNGEEvTETFNYICGC 161
Cdd:PRK06184  85 esDMFAHLEPTPDEPYPLPLMVPQWRTERILRERLAELGHRVEFGCELVGFEQDADGVTARVAGPAGEE-TVRARYLVGA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 162 DGASSTVRKRLDIGFPGGTYTQL-FYVADVEtntqLDGAS-----MGFHGNHFCVGF-PIRTTEQLRLIGIIPEEvktnG 234
Cdd:PRK06184 164 DGGRSFVRKALGIGFPGETLGIDrMLVADVS----LTGLDrdawhQWPDGDMGMIALcPLPGTDLFQIQAPLPPG----G 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 235 EPPES---FKPLIPFAENILPIHIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKL 311
Cdd:PRK06184 236 EPDLSadgLTALLAERTGRTDIRLHSVTWASAFRMNARLADRYRVGRVFLAGDAAHVHPPAGGQGLNTSVQDAYNLGWKL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 312 SNVIQGkADKSILDTYEPERIEFAKKLVNTTDTGFKFMANSQVVKDwiipyifptllhldilkkklyKTISQTAIHYKHS 391
Cdd:PRK06184 316 AAVLAG-APEALLDTYEEERRPVAAAVLGLSTELLDAIKRGDMRRG---------------------RDVQQLDLGYRGS 373

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 392 DLSI---GNYGNIAGGDRLPWIHIDSIDN-----FEPLKSRTWQIHIYGKLTQELKQfayDSQLPIYHIpwVTQMSQKDI 463
Cdd:PRK06184 374 SLAVdgpERTGGLRAGDRAPDAPLLGAAGqptrlFDLFRGPHWTLLAFGAGAAAILA---RRGLRIHRV--GDAAEGGDL 448

                        490       500
                 ....*....|....*....|....*..
gi 488391473 464 QRDA-------------VFLVRPDGYI 477
Cdd:PRK06184 449 VDDAghfrdaygltggtLVLVRPDGYV 475
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 4-339 1.13e-71

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 231.45  E-value: 1.13e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIP--IQHFNVYKDKRl 81
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPheGMGLAFYNTRR- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   82 VGKLpiakkgKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQP-NGEEVTETFNYICG 160
Cdd:pfam01494  82 RADL------DFLTSPPRVTVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDGVTAVVRDRrDGEEYTVRAKYLVG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  161 CDGASSTVRKRLDIGFPGGTYTQ------LFYVADVETNTQLDGASMGFHGNHFcVGFPIRTTEQL----RLIGIIPEEV 230
Cdd:pfam01494 156 CDGGRSPVRKTLGIEFEGFEGVPfgsldvLFDAPDLSDPVERAFVHYLIYAPHS-RGFMVGPWRSAgrerYYVQVPWDEE 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  231 KTNGEPPES---FKPLIP--FAENILPIhikNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAF 305
Cdd:pfam01494 235 VEERPEEFTdeeLKQRLRsiVGIDLALV---EILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAF 311

                         330       340       350
                  ....*....|....*....|....*....|....
gi 488391473  306 NLAWKLSNVIQGKADKSILDTYEPERIEFAKKLV 339
Cdd:pfam01494 312 NLAWKLAAVLRGQAGESLLDTYSAERLPVAWAVV 345
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-352 1.82e-69

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 224.82  E-value: 1.82e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDK- 79
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDGSd 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  80 -RLVGKLPIAKKGkdvspYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQqpNGEEVteTFNYI 158
Cdd:COG0654   82 gRVLARFDAAETG-----LPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADGVTVTLA--DGRTL--RADLV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 159 CGCDGASSTVRKRLDIGFPGGTYTQLFYVADVEtntqldgasmgfhgnhfcvgfpirtTEQLRLIGIIPEEVKtngeppe 238
Cdd:COG0654  153 VGADGARSAVRRLLGIGFTGRDYPQRALWAGVR-------------------------TELRARLAAAGPRLG------- 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 239 sfkplipfaenilpiHIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGK 318
Cdd:COG0654  201 ---------------ELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALRGR 265

                        330       340       350
                 ....*....|....*....|....*....|....
gi 488391473 319 ADKSILDTYEPERIEFAKKLVNTTDTGFKFMANS 352
Cdd:COG0654  266 DDEAALARYERERRPRAARVQRAADALGRLFHPD 299
PRK08244 PRK08244
monooxygenase;
1-494 1.61e-51

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 182.25  E-value: 1.61e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAG--IPIQHFNVYkD 78
Cdd:PRK08244   1 MKYEVIIIGGGPVGLMLASELALAGVKTCVIERLKETVPYSKALTLHPRTLEILDMRGLLERFLEKGrkLPSGHFAGL-D 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  79 KRLvgklpiakkgkDVS----PYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQQPNGEEvTET 154
Cdd:PRK08244  80 TRL-----------DFSaldtSSNYTLFLPQAETEKVLEEHARSLGVEIFRGAEVLAVRQDGDGVEVVVRGPDGLR-TLT 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 155 FNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVetnTQLDGASMGFhgnhfcvgfPIRTTEQ------------LRL 222
Cdd:PRK08244 148 SSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDV---VLKDPPPSSV---------LSLCTREggvmivplsggiYRV 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 223 IGIIPEEVKTNGEPPESfkpLIPFAENILPI-----HIKNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGM 297
Cdd:PRK08244 216 LIIDPERPQVPKDEPVT---LEELKTSLIRIcgtdfGLNDPVWMSRFGNATRQAERYRSGRIFLAGDAAHIHFPAGGQGL 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 298 NTGISDAFNLAWKLSNVIQGKADKSILDTYEPERIEFAKKLVNTTDTGFKFMANSQVVKDwiIPYIFPTLLHLDILKKKL 377
Cdd:PRK08244 293 NVGLQDAMNLGWKLAAAIKGWAPDWLLDSYHAERHPVGTALLRNTEVQTKLFDFTRPGLA--LRSMLSDLLGFPEVNRYL 370

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 378 YKTISQTAIHYKhSDLSIGNygNIAGGDRLPWIHIdSIDNFEPlkSRTWQIHIYGK-----LTQELKQFAYDSQLPIYHI 452
Cdd:PRK08244 371 AGQISALDVHYE-PDAEMPP--HPLNGKRLPDLEL-TLSDGES--ERLYSLLHKGTflllsFGSEPQDWSRYPHVRVVRA 444

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....
gi 488391473 453 pwvtQMSQKDIQRDAV--FLVRPDGYISVATNSYDVEPLKQMIE 494
Cdd:PRK08244 445 ----SLAEGRADWNDVhtALIRPDGHVAWAVDASDPNAEEAIAA 484
PRK06126 PRK06126
hypothetical protein; Provisional
 4-331 1.16e-48

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 175.57  E-value: 1.16e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIP--IQHFNVYKdKRL 81
Cdd:PRK06126   9 PVLIVGGGPVGLALALDLGRRGVDSILVERKDGTAFNPKANTTSARSMEHFRRLGIADEVRSAGLPvdYPTDIAYF-TRL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  82 VG---------------KLPIAKKGKDVSPYPYVLtLPQDIHEQILVEELEKVGG-QVCWEHELISFDDNETFISATFQQ 145
Cdd:PRK06126  88 TGyelarfrlpsareaiTPVGGPDGSWPSPELPHR-IPQKYLEPILLEHAAAQPGvTLRYGHRLTDFEQDADGVTATVED 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 146 PN-GEEVTETFNYICGCDGASSTVRKRLDIGFPGGTYTQ-----LFYVADVETNTQLDGASMgfhgnHFCVGFPIRTT-- 217
Cdd:PRK06126 167 LDgGESLTIRADYLVGCDGARSAVRRSLGISYEGTSGLQrdlsiYIRAPGLAALVGHDPAWM-----YWLFNPDRRGVlv 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 218 -----EQLRLIGIIPEEVK---TNGEPPESFKPLI--PFaenilPIHIK-NINWyssyRSHHRVAEHFRVNRAFICGDAG 286
Cdd:PRK06126 242 aidgrDEWLFHQLRGGEDEftiDDVDARAFVRRGVgeDI-----DYEVLsVVPW----TGRRLVADSYRRGRVFLAGDAA 312

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 488391473 287 HIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKADKSILDTYEPER 331
Cdd:PRK06126 313 HLFTPTGGYGMNTGIGDAVNLAWKLAAVLNGWAGPALLDSYEAER 357
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 5-335 1.38e-42

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 158.88  E-value: 1.38e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   5 VLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDKRLVgk 84
Cdd:PRK08132  26 VVVVGAGPVGLALAIDLAQQGVPVVLLDDDDTLSTGSRAICFAKRSLEIFDRLGCGERMVDKGVSWNVGKVFLRDEEV-- 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  85 lpiakkgkdvspYPYVLtLPQDIH-------------EQILVEELEKVGG-QVCWEHELISFDDNETFISATFQQPNGEE 150
Cdd:PRK08132 104 ------------YRFDL-LPEPGHrrpafinlqqyyvEGYLVERAQALPNiDLRWKNKVTGLEQHDDGVTLTVETPDGPY 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 151 vTETFNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQLD-------------GASMGFH---GNHFCVGFPI 214
Cdd:PRK08132 171 -TLEADWVIACDGARSPLREMLGLEFEGRTFEDRFLIADVKMKADFPterwfwfdppfhpGQSVLLHrqpDNVWRIDFQL 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 215 RTTEQlrligiiPEEVKTngepPESfkpLIPFAENILPIHIK-NINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAG 293
Cdd:PRK08132 250 GWDAD-------PEAEKK----PEN---VIPRVRALLGEDVPfELEWVSVYTFQCRRMDRFRHGRVLFAGDAAHQVSPFG 315

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 488391473 294 GQGMNTGISDAFNLAWKLSNVIQGKADKSILDTYEPERiEFA 335
Cdd:PRK08132 316 ARGANSGIQDADNLAWKLALVLRGRAPDSLLDSYASER-EFA 356
PRK06834 PRK06834
hypothetical protein; Provisional
 1-388 1.08e-41

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 155.56  E-value: 1.08e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTA-SRAMVVQSRVLEFYRQYDFDDKIVEAG--IPIQHFNVyk 77
Cdd:PRK06834   2 TEHAVVIAGGGPTGLMLAGELALAGVDVAIVERRPNQELVgSRAGGLHARTLEVLDQRGIADRFLAQGqvAQVTGFAA-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  78 dKRL-VGKLPiakkgkdvSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETfiSATFQQPNGEEVTEtfN 156
Cdd:PRK06834  80 -TRLdISDFP--------TRHNYGLALWQNHIERILAEWVGELGVPIYRGREVTGFAQDDT--GVDVELSDGRTLRA--Q 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 157 YICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQldgASMGFH----GNHfcvgfPIRTTEQLRLIGIIPEE--V 230
Cdd:PRK06834 147 YLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEE---PEWGVHrdalGIH-----AFGRLEDEGPVRVMVTEkqV 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 231 KTNGEPP--ESFKPLIPFAENILPIHikNINWYSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLA 308
Cdd:PRK06834 219 GATGEPTldDLREALIAVYGTDYGIH--SPTWISRFTDMARQAASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQDAVNLG 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 309 WKLSNVIQGKADKSILDTYEPERIEFAKKLVNTTdtgfkfMANS---------QVVKDwiipyIFPTLLHLDILKKKLYK 379
Cdd:PRK06834 297 WKLAQVVKGTSPESLLDTYHAERHPVAARVLRNT------MAQVallrpddrtEALRD-----IVAELLGMDEPRKRIAA 365


                 ....*....
gi 488391473 380 TISQTAIHY 388
Cdd:PRK06834 366 MMSGLDIHY 374
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-339 1.16e-41

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 155.45  E-value: 1.16e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVvqsrvlefyrqydFDDK---------IVEAGIPIQHFN 74
Cdd:PRK06183  12 DVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTLYDLPRAVG-------------IDDEalrvlqaigLADEVLPHTTPN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  75 V---YKDKRLVGKLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGG-QVCWEHELISFDDNETFISATFQQPNGEE 150
Cdd:PRK06183  79 HgmrFLDAKGRCLAEIARPSTGEFGWPRRNAFHQPLLEAVLRAGLARFPHvRVRFGHEVTALTQDDDGVTVTLTDADGQR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 151 VTETFNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQLDGasmgFHGNH-FC----------VGFPIRTTEQ 219
Cdd:PRK06183 159 ETVRARYVVGCDGANSFVRRTLGVPFEDLTFPERWLVVDVLIANDPLG----GPHTYqYCdparpytsvrLPHGRRRWEF 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 220 LRLIGIIPEEVKTngepPESFKPLI-PFAenilpIHIKNINW--YSSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQG 296
Cdd:PRK06183 235 MLLPGETEEQLAS----PENVWRLLaPWG-----PTPDDAELirHAVYTFHARVADRWRSGRVLLAGDAAHLMPPFAGQG 305

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 488391473 297 MNTGISDAFNLAWKLSNVIQGKADKSILDTYEPERIEFAKKLV 339
Cdd:PRK06183 306 MNSGIRDAANLAWKLAAVLRGRAGDALLDTYEQERRPHARAMI 348
PRK07190 PRK07190
FAD-binding protein;
4-489 3.74e-38

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 145.73  E-value: 3.74e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDKRLVG 83
Cdd:PRK07190   7 DVVIIGAGPVGLMCAYLGQLCGLNTVIVDKSDGPLEVGRADALNARTLQLLELVDLFDELYPLGKPCNTSSVWANGKFIS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  84 KLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQqpNGEEVTEtfNYICGCDG 163
Cdd:PRK07190  87 RQSSWWEELEGCLHKHFLMLGQSYVEKLLDDKLKEAGAAVKRNTSVVNIELNQAGCLTTLS--NGERIQS--RYVIGADG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 164 ASSTVRKRLDIGFPGGTYTQLFYVADVETNTQldgasmgFHGNHFCVGFPIRTTEqlrlIGIIPEE---------VKTNG 234
Cdd:PRK07190 163 SRSFVRNHFNVPFEIIRPQIIWAVIDGVIDTD-------FPKVPEIIVFQAETSD----VAWIPREgeidrfyvrMDTKD 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 235 EPPESFKPLIPFAENILPIHIKNINWYSSYRSHHRVAEHFRV-NRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSN 313
Cdd:PRK07190 232 FTLEQAIAKINHAMQPHRLGFKEIVWFSQFSVKESVAEHFFIqDRIFLAGDACHIHSVNGGQGLNTGLADAFNLIWKLNM 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 314 VIQGKADKSILDTYEPER-------IEFAKKLVNTTdtgfKFMANSQVVKDWiipyifptllhLDILKKKLyKTISQTAI 386
Cdd:PRK07190 312 VIHHGASPELLQSYEAERkpvaqgvIETSGELVRST----KYSANGTHAQDY-----------VKIVEKRA-GYITGMGI 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 387 HYKHSDLSignygniagGDRLPWIHID----SIDNFEPLKSRTWQIHIYGKLTQELKQFAYDSQLPIYHIPWVTQMSQKD 462
Cdd:PRK07190 376 RYGEEGLC---------GSRLFDFEIFqgseKTRLYSLLDYRKFTLFIFGDCEVELNVPEFVKVIHIYPQQEQANFWTRN 446

                        490       500
                 ....*....|....*....|....*...
gi 488391473 463 IQ-RDAVFLVRPDGYISVATNSYDVEPL 489
Cdd:PRK07190 447 SPyAGQAILVRPDSYIEWSVPLDQVESL 474
PRK08294 PRK08294
phenol 2-monooxygenase; Provisional
 4-340 8.80e-38

phenol 2-monooxygenase; Provisional


Pssm-ID: 236223 [Multi-domain]  Cd Length: 634  Bit Score: 146.67  E-value: 8.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSA-QGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYK----D 78
Cdd:PRK08294  34 DVLIVGCGPAGLTLAAQLSAfPDITTRIVERKPGRLELGQADGIACRTMEMFQAFGFAERILKEAYWINETAFWKpdpaD 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  79 KRlvgklPIAKKGK------DVSPYPYVLTLPQDIHEQILvEELEKVGGQVC--WEHELISF---DDNETFISATFQ--- 144
Cdd:PRK08294 114 PS-----TIVRTGRvqdtedGLSEFPHVIVNQARVHDYFL-DVMRNSPTRLEpdYGREFVDLevdEEGEYPVTVTLRrtd 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 145 -QPNGEEVTETFNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQldgasmgfhgnhfcvgFP-IRT-----T 217
Cdd:PRK08294 188 gEHEGEEETVRAKYVVGCDGARSRVRKAIGRELRGDSANHAWGVMDVLAVTD----------------FPdIRLkcaiqS 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 218 EQLRLIGIIPEE--------VKTNGEPPE--------SFKPLIPFAENILP---IHIKNINWYSSYRSHHRVAEHF---- 274
Cdd:PRK08294 252 ASEGSILLIPREggylvrlyVDLGEVPPDervavrntTVEEVIAKAQRILHpytLDVKEVAWWSVYEVGQRLTDRFddvp 331

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488391473 275 ------RVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKADKSILDTYEPERIEFAKKLVN 340
Cdd:PRK08294 332 aeeagtRLPRVFIAGDACHTHSAKAGQGMNVSMQDGFNLGWKLAAVLSGRSPPELLHTYSAERQAIAQELID 403
PRK06753 PRK06753
hypothetical protein; Provisional
 3-342 3.22e-14

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 73.95  E-value: 3.22e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   3 NDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYKDK-RL 81
Cdd:PRK06753   1 MKIAIIGAGIGGLTAAALLQEQGHEVKVFEKNESVKEVGAGIGIGDNVIKKLGNHDLAKGIKNAGQILSTMNLLDDKgTL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  82 VGKLPIAKkgkdvspYPYVLTLP-QDIHeQILVEELEkvGGQVCWEHELISFDDNETFISATFQqpNGEEvtETFNYICG 160
Cdd:PRK06753  81 LNKVKLKS-------NTLNVTLHrQTLI-DIIKSYVK--EDAIFTGKEVTKIENETDKVTIHFA--DGES--EAFDLCIG 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 161 CDGASSTVRKRLdigFPGGTYTQLFY------VADVETNTQlDGAS--MGFHGNhfcVGF-PIRTTEQLRLIGIIPEEvk 231
Cdd:PRK06753 147 ADGIHSKVRQSV---NADSKVRYQGYtcfrglIDDIDLKLP-DCAKeyWGTKGR---FGIvPLLNNQAYWFITINAKE-- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 232 tnGEPP-ESF-KPLIPFAENILPIHIKNINWYSSYRS--HHRVAE-----HFRVNRAFICGDAGHIHSPAGGQGMNTGIS 302
Cdd:PRK06753 218 --RDPKySSFgKPHLQAYFNHYPNEVREILDKQSETGilHHDIYDlkplkSFVYGRIVLLGDAAHATTPNMGQGAGQAME 295

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 488391473 303 DAFNLAWKLSNVIQGKAdksiLDTYEPERIEFAKKLVNTT 342
Cdd:PRK06753 296 DAIVLANCLNAYDFEKA----LQRYDKIRVKHTAKVIKRS 331
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 4-331 4.51e-12

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 67.61  E-value: 4.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNkgPGTASRAMVVQSRVL-------EFYRQYDFDDKIVEAGI-PIQHFNV 75
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSGLKVALIEAT--PLPAPADPGFDNRVSalsaasiRLLEKLGVWDKIEPARAqPIRDIHV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   76 YkDKRLVGKLPIAKKGKDVSPYPYVL-------TLPQDIHEQ--------ILVEELEKVGGQVCwehelISFDDNETFIS 140
Cdd:TIGR01988  79 S-DGGSFGALRFDADEIGLEALGYVVenrvlqqALWERLQELpnvtllcpARVVELPRHSDHVE-----LTLDDGQQLRA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  141 atfqqpngeevtetfNYICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQLDGASMGFHgnhfcvgFPIRTTEQL 220
Cdd:TIGR01988 153 ---------------RLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERF-------TPTGPLALL 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  221 ----RLIGII----PEEVKT-NGEPPESFKPLI--PFAENILPIHIkninwySSYRSHH----RVAEHFRVNRAFICGDA 285
Cdd:TIGR01988 211 plpdNRSSLVwtlpPEEAERlLALSDEEFLAELqrAFGSRLGAITL------VGERHAFplslTHAKRYVAPRLALIGDA 284

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 488391473  286 GH-IHsPAGGQGMNTGISDAFNLAWKLSNVI-QGK--ADKSILDTYEPER 331
Cdd:TIGR01988 285 AHtIH-PLAGQGLNLGLRDVAALAEVLEDARrRGEdiGSLRVLQRYERRR 333
PRK06475 PRK06475
FAD-binding protein;
1-337 7.95e-12

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 66.77  E-value: 7.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIpIQHFNVYKDKR 80
Cdd:PRK06475   1 TRGSPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEVGAGLQLAPNAMRHLERLGVADRLSGTGV-TPKALYLMDGR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  81 LVGKLPIAKKGKDVSPY---PYVLtlpqdIHEQilveELEKVGGQVCWEHELISFDDNETFIS---------ATFQQPNG 148
Cdd:PRK06475  80 KARPLLAMQLGDLARKRwhhPYIV-----CHRA----DLQSALLDACRNNPGIEIKLGAEMTSqrqtgnsitATIIRTNS 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 149 EEVTETfNYICGCDGASSTVRKRLDI------GFPGGTYT-------QLFYVADVETNTQLdgASMGfHGNHFcVGFPIR 215
Cdd:PRK06475 151 VETVSA-AYLIACDGVWSMLRAKAGFskarfsGHIAWRTTlaadalpASFLSAMPEHKAVS--AWLG-NKAHF-IAYPVK 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 216 TTEQLRLIGII----PEEVKTNGEPPESFKPLipFAE---NILPI--HIKNINWYSSYRSHHrvAEHFRVNRAFICGDAG 286
Cdd:PRK06475 226 GGKFFNFVAITggenPGEVWSKTGDKAHLKSI--YADwnkPVLQIlaAIDEWTYWPLFEMAD--AQFVGPDRTIFLGDAS 301

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488391473 287 HIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKAdKSILDTYEPERIEFAKK 337
Cdd:PRK06475 302 HAVTPFAAQGAAMAIEDAAALAEALDSDDQSAG-LKRFDSVRKERIAAVAK 351
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 4-331 1.22e-07

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 53.99  E-value: 1.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSA----QGISYKLIDKNKGPGTASRAM-----VVQSRV-------LEFYRQYDFDDKIVEAG 67
Cdd:TIGR01989   2 DVVIVGGGPVGLALAAALGNnpltKDLKVLLLDAVDNPKLKSRNYekpdgPYSNRVssitpasISFFKKIGAWDHIQSDR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   68 I-PIQHFNVYkDKRLVGKLPIAKKGK----------DVSPYPYVLTLPQDIHEQILVEELEKVggQVCwehELISFDDNE 136
Cdd:TIGR01989  82 IqPFGRMQVW-DGCSLALIRFDRDNGkedmaciienDNIQNSLYNRLQEYNGDNVKILNPARL--ISV---TIPSKYPND 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  137 TFISATFQQPNGEEVTETFnyICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVE--TNTQLDGASMGFHGNHFCVGFPI 214
Cdd:TIGR01989 156 NSNWVHITLSDGQVLYTKL--LIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKleEATENDVAWQRFLPTGPIALLPL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  215 RTT-----------EQLRLIGIIPEE-VK------TNGEPPESFKPLIPFAENILpihIKNINWYSSYRSHHRV------ 270
Cdd:TIGR01989 234 PDNnstlvwstspeEALRLLSLPPEDfVDalnaafDLGYSDHPYSYLLDYAMEKL---NEDIGFRTEGSKSCFQvpprvi 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  271 ----------------AEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKAD---KSILDTYEPER 331
Cdd:TIGR01989 311 gvvdksraafplglghADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADigsISSLKPYERER 390
PRK06847 PRK06847
hypothetical protein; Provisional
 3-340 2.74e-07

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 52.57  E-value: 2.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   3 NDVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDKIVEAGIPIQHFNVYK-DKRL 81
Cdd:PRK06847   5 KKVLIVGGGIGGLSAAIALRRAGIAVDLVEIDPEWRVYGAGITLQGNALRALRELGVLDECLEAGFGFDGVDLFDpDGTL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  82 VGKLPIAKKGKDvsPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQqpNGEevTETFNYICGC 161
Cdd:PRK06847  85 LAELPTPRLAGD--DLPGGGGIMRPALARILADAARAAGADVRLGTTVTAIEQDDDGVTVTFS--DGT--TGRYDLVVGA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 162 DGASSTVRKRLDIGFPGGTYT-QLFYVADVETNTQLDGASMgFHGNHFCVGF-PIrTTEQLRLIGIIPEEVKTNGEP--- 236
Cdd:PRK06847 159 DGLYSKVRSLVFPDEPEPEYTgQGVWRAVLPRPAEVDRSLM-YLGPTTKAGVvPL-SEDLMYLFVTEPRPDNPRIEPdtl 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 237 PESFKPLI-PFAENILPIHIKNINWYS--SYRSHHRVAEH---FRvNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWK 310
Cdd:PRK06847 237 AALLRELLaPFGGPVLQELREQITDDAqvVYRPLETLLVPapwHR-GRVVLIGDAAHATTPHLAQGAGMAIEDAIVLAEE 315

                        330       340       350
                 ....*....|....*....|....*....|...
gi 488391473 311 LSNviqgkaDKSI---LDTYEPERIEFAKKLVN 340
Cdd:PRK06847 316 LAR------HDSLeaaLQAYYARRWERCRMVVE 342
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
10-328 3.89e-07

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 51.51  E-value: 3.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  10 AGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEFYRQYDFDDkIVEAGIPIQHFNVYKDKRLvgKLPiak 89
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKICGGGLLPRALEELEPLGLDE-PLERPVRGARFYSPGGKSV--ELP--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  90 kgkdvSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATFQqpNGEEVteTFNYICGCDGASSTVR 169
Cdd:COG0644   75 -----PGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDDGRVVVRTG--DGEEI--RADYVVDADGARSLLA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 170 KRLDIGFPGGTYTQ----LFYVADVETNTQLDGASMGFH-GNHFCVGFP--IRTTEQLRLIGIipeevktngepPESfkp 242
Cdd:COG0644  146 RKLGLKRRSDEPQDyalaIKEHWELPPLEGVDPGAVEFFfGEGAPGGYGwvFPLGDGRVSVGI-----------PLG--- 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 243 lipfaenilpihikninwyssyrshhRVAEHFRVNRAFICGDA-GHIHsPAGGQGMNTGISDAFNLAWKLSNVIQ-GKAD 320
Cdd:COG0644  212 --------------------------GPRPRLVGDGVLLVGDAaGFVD-PLTGEGIHLAMKSGRLAAEAIAEALEgGDFS 264


                 ....*...
gi 488391473 321 KSILDTYE 328
Cdd:COG0644  265 AEALAEYE 272
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 4-38 1.06e-06

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 51.02  E-value: 1.06e-06
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPG 38
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVG 42
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 252-327 1.08e-06

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 50.95  E-value: 1.08e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488391473 252 PIHIKNInwySSYRSHhrVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKaDKSILDTY 327
Cdd:PRK08243 259 PSIEKSI---APLRSF--VAEPMQYGRLFLAGDAAHIVPPTGAKGLNLAASDVRYLARALVEFYREG-DTALLDAY 328
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 4-173 1.85e-06

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 49.62  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGTASRAMVVQSRVLEfyrQYDFDDKIVeagipiqhFNVYKDKRLVg 83
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPCGGALSPRALE---ELDLPGELI--------VNLVRGARFF- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   84 kLPIAKKGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELIS--FDDNETFISAtfqqpNGEEVTETFNYICGC 161
Cdd:TIGR02032  70 -SPNGDSVEIPIETELAYVIDRDAFDEQLAERAQEAGAELRLGTRVLDveIHDDRVVVIV-----RGSEGTVTAKIVIGA 143

                         170
                  ....*....|..
gi 488391473  162 DGASSTVRKRLD 173
Cdd:TIGR02032 144 DGSRSIVAKKLG 155
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
4-331 9.98e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 44.51  E-value: 9.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473   4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNkgPGTASR---AMVVQS-RVLE----------------FYRQYDFDDKI 63
Cdd:PRK07494   9 DIAVIGGGPAGLAAAIALARAGASVALVAPE--PPYADLrttALLGPSiRFLErlglwarlaphaaplqSMRIVDATGRL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473  64 VEAgiPIQHFNvykdkrlvgklpiakkGKDVSPYPYVLTLPQDIHEQILVEELEKVGGQVCWEHELISFDDNETFISATF 143
Cdd:PRK07494  87 IRA--PEVRFR----------------AAEIGEDAFGYNIPNWLLNRALEARVAELPNITRFGDEAESVRPREDEVTVTL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 144 QQpnGEEVTETFnyICGCDGASSTVRKRLDIGFPGGTYTQLFYVADVETNTQLDGASMGFH------------GNHFCVG 211
Cdd:PRK07494 149 AD--GTTLSARL--VVGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQNVSTEFHteggpftqvplpGRRSSLV 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 212 FPIRTTEQLRLIGIIPEEV-------------KTNGEPPESFKPLIpfaenILpihikninwyssyrshhrVAEHFRVNR 278
Cdd:PRK07494 225 WVVRPAEAERLLALSDAALsaaieermqsmlgKLTLEPGRQAWPLS-----GQ------------------VAHRFAAGR 281

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 488391473 279 AFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKADKSILDTYEPER 331
Cdd:PRK07494 282 TALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVEDRPEDPGSAAVLAAYDRAR 334
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 269-347 1.08e-04

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 44.38  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 269 RVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWK-LSNVIQGK--ADKSILDTYEPERIEFAKKLVNTTDtG 345
Cdd:PRK08850 274 RYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEiLALWQQGRdiGLKRNLRGYERWRKAEAAKMIAAMQ-G 352


                 ..
gi 488391473 346 FK 347
Cdd:PRK08850 353 FR 354
PRK09126 PRK09126
FAD-dependent hydroxylase;
1-33 2.75e-04

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 43.39  E-value: 2.75e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDK 33
Cdd:PRK09126   2 MHSDIVVVGAGPAGLSFARSLAGSGLKVTLIER 34
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-38 3.40e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 39.05  E-value: 3.40e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 488391473    7 IVGAGPSGLALTIALSAQGISYKLIDKNKGPG 38
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLG 32
HI0933_like pfam03486
HI0933-like protein;
4-38 3.73e-04

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 42.95  E-value: 3.73e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGPG 38
Cdd:pfam03486   2 DVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLG 36
PRK07364 PRK07364
FAD-dependent hydroxylase;
283-331 1.11e-03

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 41.16  E-value: 1.11e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 488391473 283 GDAGHIHSPAGGQGMNTGISDAFNLAWKLSNVIQGKAD---KSILDTYEPER 331
Cdd:PRK07364 300 GDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDigsLAVLKRYERWR 351
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
283-343 1.57e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 40.71  E-value: 1.57e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488391473 283 GDAGH-IHsPAGGQGMNTGISDAFNLAwklsNVIQGKA------DKSILDTYEPERIEFAKKLVNTTD 343
Cdd:PRK07608 286 GDAAHlIH-PLAGQGMNLGLRDVAALA----DVLAGREpfrdlgDLRLLRRYERARREDILALQVATD 348
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 4-88 3.49e-03

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 39.69  E-value: 3.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473    4 DVLIVGAGPSGLALTIALSAQGISYKLIDKNKGP--GTASRA---MVVQSRVLEFYRQYdfddKIVEAGIPI-----QHF 73
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPgsGASGRNaglIHPGLRYLEPSELA----RLALEALDLweeleEEL 76

                          90
                  ....*....|....*
gi 488391473   74 NVYKDKRLVGKLPIA 88
Cdd:pfam01266  77 GIDCGFRRCGVLVLA 91
PRK06185 PRK06185
FAD-dependent oxidoreductase;
275-308 3.52e-03

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 39.84  E-value: 3.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 488391473 275 RVNRA-------FIC-GDAGHIHSPAGGQGMNTGISDAFNLA 308
Cdd:PRK06185 274 RVDRLrrwhrpgLLCiGDAAHAMSPVGGVGINLAIQDAVAAA 315
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 1-35 5.96e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 38.89  E-value: 5.96e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 488391473   1 MSNDVLIVGAGPSGLALTIALSAQGISYKLIDKNK 35
Cdd:COG0569   94 LKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDP 128
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 262-362 6.26e-03

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 38.75  E-value: 6.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488391473 262 SSYRSHHRVAEHFRVNRAFICGDAGHIHSPAGGQGMNTGISDAFNLAWKLSNviqgkadKSILDTYEPERIE-------- 333
Cdd:PRK06617 258 SSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSN-------NGTLQEYQKLRQEdnfimykl 330

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 488391473 334 ----------FAKKLVNTTDTGFKFMANSQVVKDWIIPY 362
Cdd:PRK06617 331 tdelnnifsnYSKNLRCLRQIGFKVINNFKPIKNLITSY 369
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 5-47 9.60e-03

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 38.41  E-value: 9.60e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 488391473    5 VLIVGAGPSGLALTIALSAQGISYKLIDKNKGPGtaSRAMVVQ 47
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPG--GRAGVLE 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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