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Conserved domains on  [gi|488422417|ref|WP_002491802|]
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MULTISPECIES: peptidylprolyl isomerase [Staphylococcus]

Protein Classification

peptidylprolyl isomerase( domain architecture ID 1001668)

peptidylprolyl isomerase (PPIase) accelerates the folding of proteins; it catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

CATH:  3.10.50.40
EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0003755
PubMed:  12871165|7925971

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 143-285 1.29e-27

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 105.04  E-value: 1.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 143 KASHILIKVKSKSSDKEglsdkkAKEKAEKIQKEVEKNpNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488422417 223 LKEGEVSKVVKTDYGYHIIK-----ADKETDFNSEKSNIKQKLIEEKVQKKpklltdaYKELLKEYKV 285
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEAW-------LEELRKKAKI 143
Rotamase_2 super family cl29122
PPIC-type PPIASE domain;
14-305 1.14e-26

PPIC-type PPIASE domain;


The actual alignment was detected with superfamily member PRK03095:

Pssm-ID: 452928 [Multi-domain]  Cd Length: 287  Bit Score: 106.62  E-value: 1.14e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  14 SALLLGACGSnateSKDNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKDIDKDIKKEEKQYG 93
Cdd:PRK03095  12 SVIALSACGT----SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDKKYDEMKKQYG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  94 gkDQFESMLKQQGMSLDDYKEQKKLSAYQKQLLldKVNVSDKEIKENSK---KASHILIKVKSKSSDkeglsdkkakeka 170
Cdd:PRK03095  86 --DQFDTLLKQQGIKEETLKTGVRAQLAQEKAI--EKTITDKELKDNYKpeiKASHILVKDEATAKK------------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 171 ekiQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIKA----DKE 246
Cdd:PRK03095 149 ---VKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVtdikEPE 225

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 488422417 247 TDFNSEKSNIKQKLIEEKVQkKPKLLTDAYKELLKEYKVDYKDRDIKKAIEDSILDPDK 305
Cdd:PRK03095 226 KSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 143-285 1.29e-27

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 105.04  E-value: 1.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 143 KASHILIKVKSKSSDKEglsdkkAKEKAEKIQKEVEKNpNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488422417 223 LKEGEVSKVVKTDYGYHIIK-----ADKETDFNSEKSNIKQKLIEEKVQKKpklltdaYKELLKEYKV 285
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEAW-------LEELRKKAKI 143
prsA PRK03095
peptidylprolyl isomerase PrsA;
14-305 1.14e-26

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 106.62  E-value: 1.14e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  14 SALLLGACGSnateSKDNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKDIDKDIKKEEKQYG 93
Cdd:PRK03095  12 SVIALSACGT----SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDKKYDEMKKQYG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  94 gkDQFESMLKQQGMSLDDYKEQKKLSAYQKQLLldKVNVSDKEIKENSK---KASHILIKVKSKSSDkeglsdkkakeka 170
Cdd:PRK03095  86 --DQFDTLLKQQGIKEETLKTGVRAQLAQEKAI--EKTITDKELKDNYKpeiKASHILVKDEATAKK------------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 171 ekiQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIKA----DKE 246
Cdd:PRK03095 149 ---VKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVtdikEPE 225

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 488422417 247 TDFNSEKSNIKQKLIEEKVQkKPKLLTDAYKELLKEYKVDYKDRDIKKAIEDSILDPDK 305
Cdd:PRK03095 226 KSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 146-245 4.33e-25

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 96.60  E-value: 4.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  146 HILIKVKSKSSDKEglsdKKAKEKAEKIQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKE 225
Cdd:pfam00639   1 HILIKTPEASERDR----AEAKAKAEEILEQLKSGEDSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 488422417  226 GEVSKVVKTDYGYHIIKADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 15-297 7.52e-22

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 93.11  E-value: 7.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  15 ALLLGACGSNateskdNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKDIDKDIKKEEKQYGg 94
Cdd:PRK02998  16 VLALSACGSS------DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYK--VSDEEAKKQVEEAKDKMG- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  95 kDQFESMLKQQGM-SLDDYKEQKKLS-AYQKQLlldKVNVSDKEIKENSK---KASHILikVKSKSSDKEglsdkkakek 169
Cdd:PRK02998  87 -DNFKSTLEQVGLkNEDELKEKMKPEiAFEKAI---KATVTEKDVKDNYKpemKVSHIL--VKDEKTAKE---------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 170 aekiQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIKADKETD- 248
Cdd:PRK02998 151 ----VKEKVNNGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKEl 226

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 488422417 249 --FNSEKSNIKQKLIEEKVQK-KPKLLTDAYKELLKEYKVDYKDRDIKKAIE 297
Cdd:PRK02998 227 kpFDEVKDSIRKDLEQQRLQDtTGKWKQQVVNDLLKDADIKVNDKEFKDTFK 278
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 143-285 1.29e-27

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 105.04  E-value: 1.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 143 KASHILIKVKSKSSDKEglsdkkAKEKAEKIQKEVEKNpNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488422417 223 LKEGEVSKVVKTDYGYHIIK-----ADKETDFNSEKSNIKQKLIEEKVQKKpklltdaYKELLKEYKV 285
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEAW-------LEELRKKAKI 143
prsA PRK03095
peptidylprolyl isomerase PrsA;
14-305 1.14e-26

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 106.62  E-value: 1.14e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  14 SALLLGACGSnateSKDNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKDIDKDIKKEEKQYG 93
Cdd:PRK03095  12 SVIALSACGT----SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDKKYDEMKKQYG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  94 gkDQFESMLKQQGMSLDDYKEQKKLSAYQKQLLldKVNVSDKEIKENSK---KASHILIKVKSKSSDkeglsdkkakeka 170
Cdd:PRK03095  86 --DQFDTLLKQQGIKEETLKTGVRAQLAQEKAI--EKTITDKELKDNYKpeiKASHILVKDEATAKK------------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 171 ekiQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIKA----DKE 246
Cdd:PRK03095 149 ---VKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVtdikEPE 225

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 488422417 247 TDFNSEKSNIKQKLIEEKVQkKPKLLTDAYKELLKEYKVDYKDRDIKKAIEDSILDPDK 305
Cdd:PRK03095 226 KSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 146-245 4.33e-25

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 96.60  E-value: 4.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  146 HILIKVKSKSSDKEglsdKKAKEKAEKIQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKE 225
Cdd:pfam00639   1 HILIKTPEASERDR----AEAKAKAEEILEQLKSGEDSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 488422417  226 GEVSKVVKTDYGYHIIKADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 15-297 7.52e-22

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 93.11  E-value: 7.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  15 ALLLGACGSNateskdNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKDIDKDIKKEEKQYGg 94
Cdd:PRK02998  16 VLALSACGSS------DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYK--VSDEEAKKQVEEAKDKMG- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  95 kDQFESMLKQQGM-SLDDYKEQKKLS-AYQKQLlldKVNVSDKEIKENSK---KASHILikVKSKSSDKEglsdkkakek 169
Cdd:PRK02998  87 -DNFKSTLEQVGLkNEDELKEKMKPEiAFEKAI---KATVTEKDVKDNYKpemKVSHIL--VKDEKTAKE---------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 170 aekiQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIKADKETD- 248
Cdd:PRK02998 151 ----VKEKVNNGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKEl 226

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 488422417 249 --FNSEKSNIKQKLIEEKVQK-KPKLLTDAYKELLKEYKVDYKDRDIKKAIE 297
Cdd:PRK02998 227 kpFDEVKDSIRKDLEQQRLQDtTGKWKQQVVNDLLKDADIKVNDKEFKDTFK 278
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-293 2.05e-21

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 91.92  E-value: 2.05e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417   1 MKLMNKIIVPVTASALLLGACGSnatESKDNTLISSKAGDVKVADVMKKMGKEQIANTSFSIVLNKILADKYKdkVDTKD 80
Cdd:PRK03002   1 MRGKHIFIITALISILMLSACGQ---KNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYK--VSDDD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  81 IDKDIKKEEKQYGgkDQFESMLKQQGMS-LDDYKEQKKLSAYQKQLLldKVNVSDKEIKENSK---KASHILIKVKSKSS 156
Cdd:PRK03002  76 VDKEVQKAKSQYG--DQFKNVLKNNGLKdEADFKNQIKFKLAMNEAI--KKSVTEKDVKDHYKpeiKASHILVSDENEAK 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 157 DkeglsdkkakekaekIQKEVEKNPNkFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDY 236
Cdd:PRK03002 152 E---------------IKKKLDAGAS-FEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPN 215

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 237 GYHIIKADKETD---FNSEKSNIKQKLIEEKVqKKPKLLTDAYKELLKEYKVDYKDRDIK 293
Cdd:PRK03002 216 GYHIIKLTDKKDlkpYDEVKDSIRKNLEEERT-ADPIFGKKLLQSELKKANIKINDSELE 274
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 1.13e-20

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 90.23  E-value: 1.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417   1 MKLMNKIIVPVTASALL---LGACGSNATeskdnTLISSKAGDVKVADVMKKMGKEQIANTSF-SIVLNKILADKYKDKV 76
Cdd:PRK04405   1 MKKKMKKWALAAASAGLalsLAGCSSNQA-----TVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  77 DTKDIDKDIKKEEKQYGgkDQFESMLKQQGMSLDDYKEQKKLSAYQKQLLLDKVNVSDKEIKENSKK------ASHILik 150
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHIL-- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 151 VKSKSSDKEGLSDKkakekaekiqkeveKNPNKFGEIAKEESMDSSSAKKDGSL-GYVIKGQMVDS-FEKALFKLKEGEV 228
Cdd:PRK04405 152 VSKKSTAETVIKKL--------------KDGKDFAKLAKKYSTDTATKNKGGKLsAFDSTDTTLDStFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488422417 229 SKV-VKTDYGYHIIKADKET---DFNSEKSNIKQKLIEEKVQKKpKLLTDAYKELLKEYKVDYKDRDIKKAIED 298
Cdd:PRK04405 218 TTTpVKTTYGYEVIKMIKHPakgTFSDHKKALTKQIYAKWASDS-SVMQRVISKVLKKANVSIKDKDLKDALSS 290
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 134-243 3.07e-20

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 84.34  E-value: 3.07e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  134 DKEIKENSKKASHILIKVKSKSSDKEGLSDKKAKEKAEKIqkeveKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMV 213
Cdd:pfam13616   8 DKKSAPDSVKASHILISYSQAVSRTEEEAKAKADSLLAAL-----KNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMV 82

                          90       100       110
                  ....*....|....*....|....*....|
gi 488422417  214 DSFEKALFKLKEGEVSKVVKTDYGYHIIKA 243
Cdd:pfam13616  83 KEFEDAVFSLKVGEISGVVKTQFGFHIIKV 112
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 143-242 4.64e-19

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 81.23  E-value: 4.64e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 143 KASHILIK---VKSKSSDKEG----LSDKKAKEKAEKIQKEVEKNPNKFGEIAKEESmDSSSAKKDGSLGYVIKGQMVDS 215
Cdd:PTZ00356   7 RAAHLLIKhtgSRNPVSRRTGkpvtRSKEEAIKELAKWREQIVSGEKTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQKP 85

                         90       100
                 ....*....|....*....|....*..
gi 488422417 216 FEKALFKLKEGEVSKVVKTDYGYHIIK 242
Cdd:PTZ00356  86 FEDAAFALKVGEISDIVHTDSGVHIIL 112
prsA PRK00059
peptidylprolyl isomerase; Provisional
 79-292 1.78e-17

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 81.68  E-value: 1.78e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  79 KDIDKDIKKEEKQ-YGGKDQFESMLKQQGMSLDDYKEQKK----LSAYQKQLLLDkVNVSDKEIK----ENSKK------ 143
Cdd:PRK00059 117 KEVDKKINEIKKQfNNDEEQFEEALKATGFTEETFKEYLKnqiiIEKVINEVVKD-VKVTDKDAQkyynENKSKftekpn 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 144 ---ASHILIKVKSKSSDkeglsdkkakekaekIQKEVEKNPNkFGEIAKEESMDSSSAKKDGSLGYV--IKGQMVDSFEK 218
Cdd:PRK00059 196 tmhLAHILVKTEDEAKK---------------VKKRLDKGED-FAKVAKEVSQDPGSKDKGGDLGDVpySDSGYDKEFMD 259

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488422417 219 ALFKLKEGEVSKVVKTDYGYHIIKADKE-----TDFNSEKSNIKQKLIEekvQKKPKLLTDAYKELLKEYKVDYKDRDI 292
Cdd:PRK00059 260 GAKALKEGEISAPVKTQFGYHIIKAIKKkeypvKPFDSVKEDIKKQLLQ---EKQSEVFKKKIEEWKKALKVKKYEKNL 335
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 1-266 2.33e-10

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 60.49  E-value: 2.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417   1 MKLMNKIIVPVT--ASALLLGACGSnateSKDNT-LISSKAGDVKVADVMKKMGKEQIANTS-FSIVLNKILADKYKDKV 76
Cdd:PRK12450   1 MKQMNKLITGVVtlATVVTLSACQS----SHNNTkLVSMKGDTITVSDFYNETKNTELAQKAmLSLVISRVFETQYANKV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  77 DTKDIDKDIKKEEKQYGGkdQFESMLKQQGMSLDDYKEQ---KKLSAYQKQLLLDKVNVSDKEIKEnSKKASHILIKVKS 153
Cdd:PRK12450  77 SDKEVEKAYKQTADQYGT--SFKTVLAQSGLTPETYKKQirlTKLVEYAVKEQAKNETISKKDYRQ-AYDAYTPTMTAEI 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 154 KSSDKEglsdkkakEKAEKIQKEVEKNPNKFGEIAKEESM--DSSSAKKDGSLGYVIKGQMVdsfeKALFKLKEGEVSKV 231
Cdd:PRK12450 154 MQFEKE--------EDAKAALEAVKAEGADFAAIAKEKTIaaDKKTTYTFDSGETTLPAEVV----RAASGLKEGNRSEI 221

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 488422417 232 VK------TDYGYHII----KADKETDFNSEKSNIKQKLIEEKVQ 266
Cdd:PRK12450 222 ITaldpatSKRTYHIIkvtkKATKKADWKAYQKRLKDIIVTGKLK 266
prsA PRK01326
foldase protein PrsA; Reviewed
 13-270 3.71e-08

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 54.05  E-value: 3.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  13 ASALLLGACgSNATESKDntLISSKAGDVKVADVMKKMGKEQIANTS-FSIVLNKILADKYKDKVDTKDIDKDIKKEEKQ 91
Cdd:PRK01326  13 LSVATLAAC-SKTNENTK--VISMKGDTITVSDFYNQVKNNPSAQQAmLNLTISRVFEKQYGDKVSDKEVEKAYAKTAKQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417  92 YGgkDQFESMLKQQGMSLDDYKEQKKLSayqKQLLLDKVNVSDKEIKENSKKASH---------ILIKVKSKSSDKEGLs 162
Cdd:PRK01326  90 YG--ASFSRALAQAGLTPETYKAQIRTS---KLVEYAVKEAAKKELTDEAYKKAYeeytpevtaQIIRLDNEDKAKSVL- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 163 dkkakekaekiqKEVEKNPNKFGEIAKEesmDSSSAKKDGSLGYVIKGQMV-DSFEKALFKLKEGEVSKVVKT------D 235
Cdd:PRK01326 164 ------------EEAKAEGADFAQIAKE---NTTTKEKKGEYKFDSGSTNVpEQVKKAAFALDEDGVSDVISVldptayQ 228

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 488422417 236 YGYHIIKADKETDFNSEKSNIKQKLIEEKVQKKPK 270
Cdd:PRK01326 229 SKYYIVKVTKKTEKKSDWKDYKKRLKAIILAQKQN 263
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 179-242 1.33e-07

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 48.87  E-value: 1.33e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488422417 179 KNPNKFGEIAKEESMdSSSAKKDGSLGYVIKGQMVDSFEKALFKLKEGEVSKVVKTDYGYHIIK 242
Cdd:PRK15441  26 KNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIK 88
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 143-242 1.20e-06

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 49.74  E-value: 1.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 143 KASHILIKVKSKssdkegLSDKKAKEKAEKIQKEVEKNPNKFGEIAKEESMDSSSAKKDGSLGYVIKGQMVDSFEKALFK 222
Cdd:PRK10770 268 HARHILLKPSPI------MTDEQARAKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMR 341

                         90       100
                 ....*....|....*....|
gi 488422417 223 LKEGEVSKVVKTDYGYHIIK 242
Cdd:PRK10770 342 LNKGQISAPVHSSFGWHLIE 361
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 126-244 3.95e-06

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 48.47  E-value: 3.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488422417 126 LLDKVNVSDKEIKE------------NSKKAShiLIKVKSKSSDKEGLsdkkakekaekiqkEVEKNPNKFGEIAKEESM 193
Cdd:PRK10788 243 MQQKITVSDADIQAyydqhqdqftqpERKRYS--IIQTKTEAEAKAVL--------------DELKKGADFATLAKEKST 306

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 488422417 194 DSSSAKKDGSLGYVIKGQMVDSFEKAlfKLKE-GEVSKVVKTDYGYHIIKAD 244
Cdd:PRK10788 307 DIISARNGGDLGWLEPATTPDELKNA--GLKEkGQLSGVIKSSVGFLIVRLD 356
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
216-245 3.13e-03

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 37.04  E-value: 3.13e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 488422417  216 FEKALFKLKEGEVSKVVKTDYGYHIIKADK 245
Cdd:pfam13145  78 LAKAAFALKPGEVSGPIKTGNGYYVVRVTE 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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