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MULTISPECIES: helicase-exonuclease AddAB subunit AddB [Staphylococcus]
Protein Classification
helicase-exonuclease AddAB subunit AddB ( domain architecture ID 1006630 )
helicase-exonuclease AddAB subunit AddB is part of a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease
List of domain hits
Name
Accession
Description
Interval
E-value
addB_Gpos super family
cl33308 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1154
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
TIGR02773 :Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1322.82
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1 M EFNTYI GR A GTGK S T AML N Q IK N K M K QD P L G D PI V L IA P T Q S TFQ L E Q A FV ND S EL H G S LR TE VL H F E RL SH RV F QE V G 80
Cdd:TIGR02773 1 M GLRFIY GR S GTGK T T FII N E IK Q K I K RN P F G K PI I L LV P D Q M TFQ M E Y A LL ND I EL N G M LR AQ VL S F S RL AW RV L QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 81 GLT EQR L SKAALE M M I FHIVQQ H ESD LK L Y GSQAQYY G LSEK L A E Q I QD FK K Y N VTPE H L NQLI E NHSIQTRT K H KLED I 160
Cdd:TIGR02773 81 GLT RTF L TSTGKQ M L I RKLIEE H KDE LK V Y QKASRKK G FTAQ L S E M I TE FK R Y E VTPE D L RRMA E SITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 161 S L IY K Q L E S R MNGEFITT ED S L QQFI E ILS QS QW IK K AE VF IDGFH N F STL EY RI IEAL VQH AK Q VTV L LT T D GSH ---- 236
Cdd:TIGR02773 161 S I IY Q Q F E E R LADQYLDS ED Y L TLLA E KIP QS ED IK G AE IY IDGFH S F TPQ EY SV IEAL MKK AK K VTV S LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 237 HPF SLFR KP S EVLSH L EDI A NR L N I NLN - KTYF NT FYRYN N DD L KN LE NG FDA LQF - TPKHH Q NHVK IF ESSSM R E E INE 314
Cdd:TIGR02773 241 DEL SLFR AT S KTYYR L KQL A KE L G I DVE e PIFL NT ERPTK N KE L AH LE KQ FDA RPA i AYAEK Q ESLS IF QANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 315 VAR R IL KD VR EAD Y KFR DIAIL Y RD - E S Y AY L FESILPS Y D IP FN ID T K K SM TH HP IM E ML RS L L E VI RS NW HIN A ML R L 393
Cdd:TIGR02773 321 VAR E IL RL VR DKG Y RYK DIAIL T RD p E D Y KD L VKAVFSD Y E IP YF ID K K R SM LN HP LI E FI RS S L D VI QG NW RYE A VF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 394 F KT NV L TS --- Q F KRSSY LID L LEN F VL ER GI Y G - KRW LD ED I F SIDQ F SRMGRKSH Q l T EGHQALYKEVIKLKKNVINK 469
Cdd:TIGR02773 401 L KT GL L FP lne P F IDVRE LID Q LEN Y VL AY GI K G k KRW WK ED W F QYRR F RGLDDDFA Q - T DEEIEMQEMLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 470 VLY FE QA M NE A H TVK DY A TSF YE S LE YFE LP SQ L MTQ R DEL E LA G LT E K A E E ID Q V W NGL IQ I LD DL V T V FDDQ EM T L QQ 549
Cdd:TIGR02773 480 LFT FE KR M KK A K TVK EF A EAL YE F LE ELD LP DK L EKE R QRA E DD G RI E E A R E HE Q A W DAV IQ L LD EF V E V LGNE EM D L NL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 550 F LD V F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N K K H I YMV G M NDG I LP QTVSSSSLIT DE EKKYV E DNA h VELS P TS 629
Cdd:TIGR02773 560 F QE V I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N T K C I FLL G A NDG V LP ARPKENGILS DE DRELL E QIG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 630 DILQM DE A F VC Y I A M T RSQQSVTF SY S L MGNS G DEKEI S PFLTQIK ELF YD L EIIN L ---- QDLHKAQP L LMMQHSHQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T SASDRLKV SY P L ADAE G KSLRP S IIIHRLE ELF PK L KESL L lnep EQVSDEEQ L SYVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 706 IQ L FEY LR G W LDHED I DYR W L D A Y LAI R DD D QLN QGL D Y LTTS L T YDNET V QL N E ILSQ QLYG KT I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYP I SDV W W D V Y NWY R EE D KWK QGL E Y VLSG L F YDNET K QL Q E SKAK QLYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 786 F K H Y A SH GL R L N ER TK Y E L QNF DLG DI FH SV LK Y ISD RIYG --- D FKN L DTKNIQSLTKE A L E LIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GL K L K ER KI Y K L EAP DLG QL FH EA LK E ISD ELKE ekl D WSD L TKEQCRLFAND A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 863 K Y LS KK IGS IV ETTLKA L KY Q GEY S K FVP QRF E T GF R ksp KN K GE L VAQP L ITNQ G IPINI RG Q IDR I D TYT K G D HS Y VN 942
Cdd:TIGR02773 879 R Y VQ KK LKR IV TRAVGV L SE Q AKR S G FVP VGL E L GF G --- FG K NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ET Y LR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 943 IIDYKS se SS AT LDLT K VYYGL QM QM M TY M DIVL Q N KERLGLTDI v K P G G L LYFH V H E P R I KF K SW ad ID E DQFQKDYI K 1022
Cdd:TIGR02773 956 IIDYKS -- SS KG LDLT E VYYGL AL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEIEQEIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1023 NF KM S GLL NR DQEV LDAL D IR LE PK y N S D I V P IA L TAK G AINQ R s SK V A D E NIIYQ L IE H NKKN F I E TASH I M DG HTEVA 1102
Cdd:TIGR02773 1031 EY KM K GLL LS DQEV VRLM D TT LE EG - S S N I I P AS L KKD G SLGS R - SK A A T E EEFEL L RK H VRRK F Q E AGEN I T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|..
gi 488428184 1103 P L K Y K QVL PCQ F CN YK SVC HV D GLIDSKR YR TV d E SI K PLDLIQQLRN E G G E 1154
Cdd:TIGR02773 1109 P Y K M K KQT PCQ Y CN FS SVC QF D TSLEENE YR HL - E AE K DETILEWINE E V G G 1159
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1154
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1322.82
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1 M EFNTYI GR A GTGK S T AML N Q IK N K M K QD P L G D PI V L IA P T Q S TFQ L E Q A FV ND S EL H G S LR TE VL H F E RL SH RV F QE V G 80
Cdd:TIGR02773 1 M GLRFIY GR S GTGK T T FII N E IK Q K I K RN P F G K PI I L LV P D Q M TFQ M E Y A LL ND I EL N G M LR AQ VL S F S RL AW RV L QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 81 GLT EQR L SKAALE M M I FHIVQQ H ESD LK L Y GSQAQYY G LSEK L A E Q I QD FK K Y N VTPE H L NQLI E NHSIQTRT K H KLED I 160
Cdd:TIGR02773 81 GLT RTF L TSTGKQ M L I RKLIEE H KDE LK V Y QKASRKK G FTAQ L S E M I TE FK R Y E VTPE D L RRMA E SITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 161 S L IY K Q L E S R MNGEFITT ED S L QQFI E ILS QS QW IK K AE VF IDGFH N F STL EY RI IEAL VQH AK Q VTV L LT T D GSH ---- 236
Cdd:TIGR02773 161 S I IY Q Q F E E R LADQYLDS ED Y L TLLA E KIP QS ED IK G AE IY IDGFH S F TPQ EY SV IEAL MKK AK K VTV S LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 237 HPF SLFR KP S EVLSH L EDI A NR L N I NLN - KTYF NT FYRYN N DD L KN LE NG FDA LQF - TPKHH Q NHVK IF ESSSM R E E INE 314
Cdd:TIGR02773 241 DEL SLFR AT S KTYYR L KQL A KE L G I DVE e PIFL NT ERPTK N KE L AH LE KQ FDA RPA i AYAEK Q ESLS IF QANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 315 VAR R IL KD VR EAD Y KFR DIAIL Y RD - E S Y AY L FESILPS Y D IP FN ID T K K SM TH HP IM E ML RS L L E VI RS NW HIN A ML R L 393
Cdd:TIGR02773 321 VAR E IL RL VR DKG Y RYK DIAIL T RD p E D Y KD L VKAVFSD Y E IP YF ID K K R SM LN HP LI E FI RS S L D VI QG NW RYE A VF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 394 F KT NV L TS --- Q F KRSSY LID L LEN F VL ER GI Y G - KRW LD ED I F SIDQ F SRMGRKSH Q l T EGHQALYKEVIKLKKNVINK 469
Cdd:TIGR02773 401 L KT GL L FP lne P F IDVRE LID Q LEN Y VL AY GI K G k KRW WK ED W F QYRR F RGLDDDFA Q - T DEEIEMQEMLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 470 VLY FE QA M NE A H TVK DY A TSF YE S LE YFE LP SQ L MTQ R DEL E LA G LT E K A E E ID Q V W NGL IQ I LD DL V T V FDDQ EM T L QQ 549
Cdd:TIGR02773 480 LFT FE KR M KK A K TVK EF A EAL YE F LE ELD LP DK L EKE R QRA E DD G RI E E A R E HE Q A W DAV IQ L LD EF V E V LGNE EM D L NL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 550 F LD V F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N K K H I YMV G M NDG I LP QTVSSSSLIT DE EKKYV E DNA h VELS P TS 629
Cdd:TIGR02773 560 F QE V I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N T K C I FLL G A NDG V LP ARPKENGILS DE DRELL E QIG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 630 DILQM DE A F VC Y I A M T RSQQSVTF SY S L MGNS G DEKEI S PFLTQIK ELF YD L EIIN L ---- QDLHKAQP L LMMQHSHQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T SASDRLKV SY P L ADAE G KSLRP S IIIHRLE ELF PK L KESL L lnep EQVSDEEQ L SYVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 706 IQ L FEY LR G W LDHED I DYR W L D A Y LAI R DD D QLN QGL D Y LTTS L T YDNET V QL N E ILSQ QLYG KT I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYP I SDV W W D V Y NWY R EE D KWK QGL E Y VLSG L F YDNET K QL Q E SKAK QLYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 786 F K H Y A SH GL R L N ER TK Y E L QNF DLG DI FH SV LK Y ISD RIYG --- D FKN L DTKNIQSLTKE A L E LIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GL K L K ER KI Y K L EAP DLG QL FH EA LK E ISD ELKE ekl D WSD L TKEQCRLFAND A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 863 K Y LS KK IGS IV ETTLKA L KY Q GEY S K FVP QRF E T GF R ksp KN K GE L VAQP L ITNQ G IPINI RG Q IDR I D TYT K G D HS Y VN 942
Cdd:TIGR02773 879 R Y VQ KK LKR IV TRAVGV L SE Q AKR S G FVP VGL E L GF G --- FG K NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ET Y LR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 943 IIDYKS se SS AT LDLT K VYYGL QM QM M TY M DIVL Q N KERLGLTDI v K P G G L LYFH V H E P R I KF K SW ad ID E DQFQKDYI K 1022
Cdd:TIGR02773 956 IIDYKS -- SS KG LDLT E VYYGL AL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEIEQEIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1023 NF KM S GLL NR DQEV LDAL D IR LE PK y N S D I V P IA L TAK G AINQ R s SK V A D E NIIYQ L IE H NKKN F I E TASH I M DG HTEVA 1102
Cdd:TIGR02773 1031 EY KM K GLL LS DQEV VRLM D TT LE EG - S S N I I P AS L KKD G SLGS R - SK A A T E EEFEL L RK H VRRK F Q E AGEN I T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|..
gi 488428184 1103 P L K Y K QVL PCQ F CN YK SVC HV D GLIDSKR YR TV d E SI K PLDLIQQLRN E G G E 1154
Cdd:TIGR02773 1109 P Y K M K KQT PCQ Y CN FS SVC QF D TSLEENE YR HL - E AE K DETILEWINE E V G G 1159
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
6-1138
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 932.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 6 YI GRAG T GK S T AM L NQ IK NKM K Q dpl G D PI V L IA P T Q S TFQ L E Q A FVNDSE L H GS L R TE VL H F E RL SH RV F QE V GG L T EQ 85
Cdd:COG3857 3 IL GRAG S GK T T YL L EE IK EEL K E --- G K PI I L LV P E Q M TFQ A E R A LLKRLG L G GS I R AQ VL S F S RL AW RV L QE T GG A T RP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 86 R LS K A ALE M MIFH I VQQ H ESD LK LYGSQ A QYY G LS E K LAE Q I QDF K K Y NV TPE H L NQLI E NH siqtrt K H KL E D IS LIY K 165
Cdd:COG3857 80 L LS D A GKR M LLRK I LEE H KDE LK VFARA A DKP G FI E Q LAE L I TEL K R Y GI TPE D L EEAA E LL ------ K E KL R D LA LIY E 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 166 QL E SRMN G EF I TT ED S L QQFI E I L SQ S QWIKK AE VF IDGF HN F STL E YRII EAL VQH AK Q VT VL LT T D gs HHPFS LF RKP 245
Cdd:COG3857 154 AY E EKLA G RY I DS ED L L RLLA E K L EK S EFLEG AE IY IDGF TD F TPQ E LELL EAL LKK AK E VT IT LT L D -- PDELD LF SAT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 246 S E VLSH L EDI A NRLNINLNK tyfntfyr YNNDD L KN LE NGFD A LQ ft P KHHQNHVK I F E SSSM R E E INE VAR R I LKD VRE 325
Cdd:COG3857 232 G E TYER L LEL A KENGVEVEF -------- KKSPE L AH LE RNLF A YP -- P EEEPEGIE I I E AANR R A E VEA VAR E I RRL VRE 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 326 AD Y KF RDIA ILY RD - E S YA Y L F E SILPS Y D IP FN ID T K KSMT HHP IM E MLR SLLE VI RSN WHINAML RL F KT N v L TSQFK 404
Cdd:COG3857 302 EG Y RY RDIA VVV RD l E A YA P L I E RVFAE Y G IP YF ID E K RPLS HHP LV E LIL SLLE LV RSN FRYEDVF RL L KT G - L LRPLS 380
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 405 R SS yl ID L LEN F VL ER GI Y G K RWL DEDIFSID qfsrmgrksh Q LT EGHQALYKEVIK L KKNVINKV L YFEQAMNE A H TV K 484
Cdd:COG3857 381 R EE -- ID R LEN Y VL AY GI R G R RWL ERYLEEEE ---------- E LT DEEEEDLERLNE L RDRLLEPL L PLRERLKK A K TV R 448
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 485 DY A TSF YE S LE YFEL P SQ L MTQ R d E L E L AG LT E K A E E ID Q V WN G LI QI LD D LV T V FD D QEMT L QQ FL DVFDI GLE Q L E F V 564
Cdd:COG3857 449 EW A EAL YE F LE ELGV P EK L EEW R - E A E E AG DL E E A R E HE Q A WN A LI EL LD E LV E V LG D EKLS L EE FL RILES GLE E L T F G 527
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 565 M IP QT LDQV SI G TM D L A KVDNK K HIYMV G M N D G IL P QTVSSSS L IT DEE KKYVED n AHV EL S PTS DILQMD E A F VC Y I A M 644
Cdd:COG3857 528 L IP PS LDQV QV G GL D R A RGLDF K AVFVL G L N E G VF P ARPREDG L LS DEE RERLNE - LGL EL P PTS RERLLE E R F LF Y R A L 606
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 645 TR SQQSVTF SY S L MGNS G DEKEI SP FLTQIK ELF YD LE IIN L Q dlhk AQP L LMMQHSHQTKIQ L FEY LR GW ldhe DIDYR 724
Cdd:COG3857 607 TR ASERLYL SY P L ADEE G KALLP SP LIDRLR ELF PE LE ERS L L ---- EEE L EYIGTPESALSE L AAA LR QL ---- ELAPL 678
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 725 W L D A Y LAI rdddqlnqgldylttsltydnetvqlneilsqqlygkt INA SVSR F E G Y QQ CPF KHYASH GL R L N ER TK YEL 804
Cdd:COG3857 679 W W D V Y KWL -------------------------------------- LKL SVSR L E T Y AA CPF QFFLRY GL K L K ER EE YEL 720
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 805 QNF D L G DI FH S VL KYISDRIYG --- D FKN L DTKNIQS L TK EA L E LIL P KV Q FNL L N SSA Y Y K YL SKKIGSIVETTLKA L K 881
Cdd:COG3857 721 DAP D R G TL FH A VL ERFYKELKE egl D WAD L SDEELEE L LE EA V E ELA P EL Q NGI L L SSA R Y R YL LERLKRLLKRARRW L E 800
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 882 YQGEY S K F V P QRF E TG F RK spkn K G E L VAQP L ITNQ G IP I NI RG Q IDRID TYTKGDH s Y VN IIDYKS se S S ATL DL TK VY 961
Cdd:COG3857 801 EEARR S G F E P VAL E LS F GP ---- E G G L PPLE L ELPN G RK I RL RG R IDRID RLESDGR - Y LR IIDYKS -- G S KKF DL DD VY 873
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 962 YGL QM Q MMT Y M D IV L Q N K E rlgl TDIVK P G G L LYFH VHE P RI K F K SW adidedqfqkdy I K NF KM S GLL NR D Q EVL DA ld 1041
Cdd:COG3857 874 YGL AL Q LPL Y L D AA L E N L E ---- GKEAE P A G A LYFH LKN P KL K A K KP ------------ L K KL KM K GLL LD D P EVL EI -- 935
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1042 irlepkynsdivp I A L TAK G AI nq RS SKV AD E NIIYQ L IE H NKKNFI E TASH I MD G HTEVA P LKY K QVLP CQ F C N YKS V C 1121
Cdd:COG3857 936 ------------- I P L KKD G SF -- KN SKV LS E EEFEE L LD H VRELLK E AGEE I LA G DFAIN P YRT K DRTA CQ Y C P YKS I C 1000
1130
....*....|....*..
gi 488428184 1122 HV D GLIDSKR YR TVDES 1138
Cdd:COG3857 1001 RF D ESLEGNE YR KLKKK 1017
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
774-1004
5.81e-29
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 116.86
E-value: 5.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 774 S V SR F E G Y QQ CP FKHYASHG L R L ne R TKY EL QNF DLG DIF H SV L K yisd R I Y g DFKN L DTKNIQS L TKEA LE LIL P KV q F 853
Cdd:pfam12705 3 S P SR L E T Y LT CP LRFFLRYL L G L -- R EDE EL DAP DLG TLV H AA L E ---- R F Y - RWGR L PEEDLEE L LQAL LE ELW P EL - G 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 854 NLLNSSAYYKY L SKKIGSIV E TT L KA L KYQGEYS - K F V P QRF E T GF rkspknkgelvaqplitn Q G IPINIR G Q IDR I D T 932
Cdd:pfam12705 75 LQSEILPRLPW L AGRLRRRL E RM L RR L AEWLRAR r G F R P VAV E L GF ------------------ G G TTVRLV G R IDR V D L 136
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488428184 933 YTK G dhs Y VN IIDYK SSESSATLDLTKV Y Y GL qm Q MMT Y MDIVLQNKER LG ltdiv K P G G L LY FHVHE P RI K 1004
Cdd:pfam12705 137 DGE G --- Y LR IIDYK TGSAPPQSEDLDL Y E GL -- Q LLL Y LLALAAGEKA LG ----- G P A G A LY LRLDD P LK K 198
PRK10919
PRK10919 ATP-dependent DNA helicase Rep; Provisional
200-654
4.62e-06
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain]
Cd Length: 672
Bit Score: 50.99
E-value: 4.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 200 VFI D GFHNFS T LE Y RIIEA LV QHAKQV TV LLTT D G S HHPFSLF R KPSE VL SH l E D IANRLN I N L NKT Y FNT -- FYRYN N D 277
Cdd:PRK10919 211 LLV D EYQDTN T SQ Y ELVKL LV GSRARF TV VGDD D Q S IYSWRGA R PQNL VL LS - Q D FPALQV I K L EQN Y RSS gr ILKAA N I 289
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 278 DLK N LENG F DALQ F TPKHHQNHV K IFESSSMRE E INE V ARRILKD -- V READ YK fr D I AILYR DESYAYL FE SI L PSYD I 355
Cdd:PRK10919 290 LIA N NPHV F EKRL F SELGYGDEL K VLSANNEEH E AER V TGELIAH hf V NKTQ YK -- D Y AILYR GNHQSRV FE KF L MQNR I 367
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 356 P FN I DTKK S MTHH P IMEM L RSL L E V IRSNWHIN A M LR LFK T ----- NVL T S Q ------ FK R SSY L IDLLENFV L ERGIY G 424
Cdd:PRK10919 368 P YK I SGGT S FFSR P EIKD L LAY L R V LTNPDDDS A F LR IVN T pkrei GPA T L Q klgewa MT R NKS L FTASFDMG L SQTLS G 447
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 425 k R WLD edif S IDQ F SRMGRKSHQ L T E ghqaly K E VIKLKKNV I NKV lyfeqamneahtvk DY ATSF YE SL eyfel PS qlm 504
Cdd:PRK10919 448 - R GYE ---- S LTR F THWLAEIQR L A E ------ R E PVAAVRDL I HGI -------------- DY ESWL YE TS ----- PS --- 494
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 505 tqrdelelaglt E KA E E ----- ID Q VWNGLIQI L -- DD L vtvfd D QE MTL Q Q FLDV F DI g LEQL E FVMIPQT LDQV SIG T 577
Cdd:PRK10919 495 ------------ P KA A E mrmkn VN Q LFSWMTEM L eg SE L ----- D EP MTL T Q VVTR F TL - RDMM E RGESEEE LDQV QLM T 556
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488428184 578 MDLA K VDNKKHI Y M VGM ND G I LP QTV S SSSLIT DEE KK yvednahvelsptsdilqmdeaf VC Y IAM TR S Q QSV TF S 654
Cdd:PRK10919 557 LHAS K GLEFPYV Y L VGM EE G L LP HQS S IDEDNI DEE RR ----------------------- LA Y VGI TR A Q KEL TF T 610
SF1_C_UvrD
cd18807 C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ...
300-350
3.17e-03
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain]
Cd Length: 150
Bit Score: 39.52
E-value: 3.17e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 488428184 300 V KIFESSSMRE E INEV A RR I LKDVREADYKFR DIAIL Y R DESY A YLF E SI L 350
Cdd:cd18807 34 V ELLLAKDEAD E AKAI A DE I KRLIESGPVQYS DIAIL V R TNRQ A RVI E EA L 84
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1154
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1322.82
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1 M EFNTYI GR A GTGK S T AML N Q IK N K M K QD P L G D PI V L IA P T Q S TFQ L E Q A FV ND S EL H G S LR TE VL H F E RL SH RV F QE V G 80
Cdd:TIGR02773 1 M GLRFIY GR S GTGK T T FII N E IK Q K I K RN P F G K PI I L LV P D Q M TFQ M E Y A LL ND I EL N G M LR AQ VL S F S RL AW RV L QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 81 GLT EQR L SKAALE M M I FHIVQQ H ESD LK L Y GSQAQYY G LSEK L A E Q I QD FK K Y N VTPE H L NQLI E NHSIQTRT K H KLED I 160
Cdd:TIGR02773 81 GLT RTF L TSTGKQ M L I RKLIEE H KDE LK V Y QKASRKK G FTAQ L S E M I TE FK R Y E VTPE D L RRMA E SITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 161 S L IY K Q L E S R MNGEFITT ED S L QQFI E ILS QS QW IK K AE VF IDGFH N F STL EY RI IEAL VQH AK Q VTV L LT T D GSH ---- 236
Cdd:TIGR02773 161 S I IY Q Q F E E R LADQYLDS ED Y L TLLA E KIP QS ED IK G AE IY IDGFH S F TPQ EY SV IEAL MKK AK K VTV S LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 237 HPF SLFR KP S EVLSH L EDI A NR L N I NLN - KTYF NT FYRYN N DD L KN LE NG FDA LQF - TPKHH Q NHVK IF ESSSM R E E INE 314
Cdd:TIGR02773 241 DEL SLFR AT S KTYYR L KQL A KE L G I DVE e PIFL NT ERPTK N KE L AH LE KQ FDA RPA i AYAEK Q ESLS IF QANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 315 VAR R IL KD VR EAD Y KFR DIAIL Y RD - E S Y AY L FESILPS Y D IP FN ID T K K SM TH HP IM E ML RS L L E VI RS NW HIN A ML R L 393
Cdd:TIGR02773 321 VAR E IL RL VR DKG Y RYK DIAIL T RD p E D Y KD L VKAVFSD Y E IP YF ID K K R SM LN HP LI E FI RS S L D VI QG NW RYE A VF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 394 F KT NV L TS --- Q F KRSSY LID L LEN F VL ER GI Y G - KRW LD ED I F SIDQ F SRMGRKSH Q l T EGHQALYKEVIKLKKNVINK 469
Cdd:TIGR02773 401 L KT GL L FP lne P F IDVRE LID Q LEN Y VL AY GI K G k KRW WK ED W F QYRR F RGLDDDFA Q - T DEEIEMQEMLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 470 VLY FE QA M NE A H TVK DY A TSF YE S LE YFE LP SQ L MTQ R DEL E LA G LT E K A E E ID Q V W NGL IQ I LD DL V T V FDDQ EM T L QQ 549
Cdd:TIGR02773 480 LFT FE KR M KK A K TVK EF A EAL YE F LE ELD LP DK L EKE R QRA E DD G RI E E A R E HE Q A W DAV IQ L LD EF V E V LGNE EM D L NL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 550 F LD V F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N K K H I YMV G M NDG I LP QTVSSSSLIT DE EKKYV E DNA h VELS P TS 629
Cdd:TIGR02773 560 F QE V I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N T K C I FLL G A NDG V LP ARPKENGILS DE DRELL E QIG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 630 DILQM DE A F VC Y I A M T RSQQSVTF SY S L MGNS G DEKEI S PFLTQIK ELF YD L EIIN L ---- QDLHKAQP L LMMQHSHQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T SASDRLKV SY P L ADAE G KSLRP S IIIHRLE ELF PK L KESL L lnep EQVSDEEQ L SYVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 706 IQ L FEY LR G W LDHED I DYR W L D A Y LAI R DD D QLN QGL D Y LTTS L T YDNET V QL N E ILSQ QLYG KT I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYP I SDV W W D V Y NWY R EE D KWK QGL E Y VLSG L F YDNET K QL Q E SKAK QLYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 786 F K H Y A SH GL R L N ER TK Y E L QNF DLG DI FH SV LK Y ISD RIYG --- D FKN L DTKNIQSLTKE A L E LIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GL K L K ER KI Y K L EAP DLG QL FH EA LK E ISD ELKE ekl D WSD L TKEQCRLFAND A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 863 K Y LS KK IGS IV ETTLKA L KY Q GEY S K FVP QRF E T GF R ksp KN K GE L VAQP L ITNQ G IPINI RG Q IDR I D TYT K G D HS Y VN 942
Cdd:TIGR02773 879 R Y VQ KK LKR IV TRAVGV L SE Q AKR S G FVP VGL E L GF G --- FG K NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ET Y LR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 943 IIDYKS se SS AT LDLT K VYYGL QM QM M TY M DIVL Q N KERLGLTDI v K P G G L LYFH V H E P R I KF K SW ad ID E DQFQKDYI K 1022
Cdd:TIGR02773 956 IIDYKS -- SS KG LDLT E VYYGL AL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEIEQEIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1023 NF KM S GLL NR DQEV LDAL D IR LE PK y N S D I V P IA L TAK G AINQ R s SK V A D E NIIYQ L IE H NKKN F I E TASH I M DG HTEVA 1102
Cdd:TIGR02773 1031 EY KM K GLL LS DQEV VRLM D TT LE EG - S S N I I P AS L KKD G SLGS R - SK A A T E EEFEL L RK H VRRK F Q E AGEN I T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|..
gi 488428184 1103 P L K Y K QVL PCQ F CN YK SVC HV D GLIDSKR YR TV d E SI K PLDLIQQLRN E G G E 1154
Cdd:TIGR02773 1109 P Y K M K KQT PCQ Y CN FS SVC QF D TSLEENE YR HL - E AE K DETILEWINE E V G G 1159
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
6-1138
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 932.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 6 YI GRAG T GK S T AM L NQ IK NKM K Q dpl G D PI V L IA P T Q S TFQ L E Q A FVNDSE L H GS L R TE VL H F E RL SH RV F QE V GG L T EQ 85
Cdd:COG3857 3 IL GRAG S GK T T YL L EE IK EEL K E --- G K PI I L LV P E Q M TFQ A E R A LLKRLG L G GS I R AQ VL S F S RL AW RV L QE T GG A T RP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 86 R LS K A ALE M MIFH I VQQ H ESD LK LYGSQ A QYY G LS E K LAE Q I QDF K K Y NV TPE H L NQLI E NH siqtrt K H KL E D IS LIY K 165
Cdd:COG3857 80 L LS D A GKR M LLRK I LEE H KDE LK VFARA A DKP G FI E Q LAE L I TEL K R Y GI TPE D L EEAA E LL ------ K E KL R D LA LIY E 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 166 QL E SRMN G EF I TT ED S L QQFI E I L SQ S QWIKK AE VF IDGF HN F STL E YRII EAL VQH AK Q VT VL LT T D gs HHPFS LF RKP 245
Cdd:COG3857 154 AY E EKLA G RY I DS ED L L RLLA E K L EK S EFLEG AE IY IDGF TD F TPQ E LELL EAL LKK AK E VT IT LT L D -- PDELD LF SAT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 246 S E VLSH L EDI A NRLNINLNK tyfntfyr YNNDD L KN LE NGFD A LQ ft P KHHQNHVK I F E SSSM R E E INE VAR R I LKD VRE 325
Cdd:COG3857 232 G E TYER L LEL A KENGVEVEF -------- KKSPE L AH LE RNLF A YP -- P EEEPEGIE I I E AANR R A E VEA VAR E I RRL VRE 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 326 AD Y KF RDIA ILY RD - E S YA Y L F E SILPS Y D IP FN ID T K KSMT HHP IM E MLR SLLE VI RSN WHINAML RL F KT N v L TSQFK 404
Cdd:COG3857 302 EG Y RY RDIA VVV RD l E A YA P L I E RVFAE Y G IP YF ID E K RPLS HHP LV E LIL SLLE LV RSN FRYEDVF RL L KT G - L LRPLS 380
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 405 R SS yl ID L LEN F VL ER GI Y G K RWL DEDIFSID qfsrmgrksh Q LT EGHQALYKEVIK L KKNVINKV L YFEQAMNE A H TV K 484
Cdd:COG3857 381 R EE -- ID R LEN Y VL AY GI R G R RWL ERYLEEEE ---------- E LT DEEEEDLERLNE L RDRLLEPL L PLRERLKK A K TV R 448
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 485 DY A TSF YE S LE YFEL P SQ L MTQ R d E L E L AG LT E K A E E ID Q V WN G LI QI LD D LV T V FD D QEMT L QQ FL DVFDI GLE Q L E F V 564
Cdd:COG3857 449 EW A EAL YE F LE ELGV P EK L EEW R - E A E E AG DL E E A R E HE Q A WN A LI EL LD E LV E V LG D EKLS L EE FL RILES GLE E L T F G 527
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 565 M IP QT LDQV SI G TM D L A KVDNK K HIYMV G M N D G IL P QTVSSSS L IT DEE KKYVED n AHV EL S PTS DILQMD E A F VC Y I A M 644
Cdd:COG3857 528 L IP PS LDQV QV G GL D R A RGLDF K AVFVL G L N E G VF P ARPREDG L LS DEE RERLNE - LGL EL P PTS RERLLE E R F LF Y R A L 606
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 645 TR SQQSVTF SY S L MGNS G DEKEI SP FLTQIK ELF YD LE IIN L Q dlhk AQP L LMMQHSHQTKIQ L FEY LR GW ldhe DIDYR 724
Cdd:COG3857 607 TR ASERLYL SY P L ADEE G KALLP SP LIDRLR ELF PE LE ERS L L ---- EEE L EYIGTPESALSE L AAA LR QL ---- ELAPL 678
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 725 W L D A Y LAI rdddqlnqgldylttsltydnetvqlneilsqqlygkt INA SVSR F E G Y QQ CPF KHYASH GL R L N ER TK YEL 804
Cdd:COG3857 679 W W D V Y KWL -------------------------------------- LKL SVSR L E T Y AA CPF QFFLRY GL K L K ER EE YEL 720
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 805 QNF D L G DI FH S VL KYISDRIYG --- D FKN L DTKNIQS L TK EA L E LIL P KV Q FNL L N SSA Y Y K YL SKKIGSIVETTLKA L K 881
Cdd:COG3857 721 DAP D R G TL FH A VL ERFYKELKE egl D WAD L SDEELEE L LE EA V E ELA P EL Q NGI L L SSA R Y R YL LERLKRLLKRARRW L E 800
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 882 YQGEY S K F V P QRF E TG F RK spkn K G E L VAQP L ITNQ G IP I NI RG Q IDRID TYTKGDH s Y VN IIDYKS se S S ATL DL TK VY 961
Cdd:COG3857 801 EEARR S G F E P VAL E LS F GP ---- E G G L PPLE L ELPN G RK I RL RG R IDRID RLESDGR - Y LR IIDYKS -- G S KKF DL DD VY 873
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 962 YGL QM Q MMT Y M D IV L Q N K E rlgl TDIVK P G G L LYFH VHE P RI K F K SW adidedqfqkdy I K NF KM S GLL NR D Q EVL DA ld 1041
Cdd:COG3857 874 YGL AL Q LPL Y L D AA L E N L E ---- GKEAE P A G A LYFH LKN P KL K A K KP ------------ L K KL KM K GLL LD D P EVL EI -- 935
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1042 irlepkynsdivp I A L TAK G AI nq RS SKV AD E NIIYQ L IE H NKKNFI E TASH I MD G HTEVA P LKY K QVLP CQ F C N YKS V C 1121
Cdd:COG3857 936 ------------- I P L KKD G SF -- KN SKV LS E EEFEE L LD H VRELLK E AGEE I LA G DFAIN P YRT K DRTA CQ Y C P YKS I C 1000
1130
....*....|....*..
gi 488428184 1122 HV D GLIDSKR YR TVDES 1138
Cdd:COG3857 1001 RF D ESLEGNE YR KLKKK 1017
rexB_recomb
TIGR02774 ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in ...
32-1103
3.92e-48
ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274291 [Multi-domain]
Cd Length: 1076
Bit Score: 187.35
E-value: 3.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 32 G DPIVL IAP TQST F QL E Q A FVNDSELHG S LRTE V LH F ERLS h R V F QEVGGLTEQR L SKAA L E M MIFHIVQ Q H E - S DLK L Y 110
Cdd:TIGR02774 26 G KRVFY IAP NSLS F EK E R A VLEYLPQQA S FSIT V TR F AQMA - R Y F VLNDLPAKTT L DDIG L A M IFYRALA Q L E p G DLK V Y 104
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 111 G SQA Q YYGLSEK L A E QIQDFK K YNVTPEH L NQ L ien H S IQ trtkh K L ED ISL I YKQLESRM N GEFITTEDS L QQ FIE ILS 190
Cdd:TIGR02774 105 G RLK Q DPQFIQQ L V E LYKELQ K SQLSILD L EN L --- T S PD ----- K R ED LLA I FEKVTAYL N QGQYAQQSK L AH FIE AIE 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 191 Q --- SQWI K KAEVF IDGF HN FS TL E YRIIEA L vq H A K Q V TVLLTTDG S HH ---- P FS LFRKPSEVLSH L E D I A NRLNINL 263
Cdd:TIGR02774 177 S gkl DSDL K NTVLV IDGF TR FS AE E EALVSL L -- H G K G V EIIIGAYA S QK ayks S FS EGNLYQASVKF L H D L A QKYQTKA 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 264 NKTYFNTFYRYNN D D L - KN LE NGF D ALQFTP --- KHHQNHVK I FESSSMR EE INE VAR R I LKDVR E A d Y KFR DI AI L YR D 339
Cdd:TIGR02774 255 EFISSTHESKDSF D K L s RL LE ASH D FSELAL dld DKDKDNLT I WSCLTQK EE VEH VAR S I RQKLY E G - Y RYK DI LV L LG D 333
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 340 - E SY AYLFES I LPS YDIPF NIDTKKS M T HHP IMEMLR SL LEVI R SNWHINAM L R L F KT NVLT s Q F KR S S yl ID LL E NFVL 418
Cdd:TIGR02774 334 v D SY QLQLGK I FDQ YDIPF YLGKAEP M A HHP LVQFIE SL ERIK R YRFRAEDV L N L L KT GLYG - D F SQ S D -- ID AF E QYIR 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 419 ERG I Y G KRWLDEDI ------- F SI D QFSRMGRK shq LTEGHQA L Y K EVIK L KKNVI NK VLY F EQAMNEAHTVK D yatsfy 491
Cdd:TIGR02774 411 YAD I K G LPKFQKTF tknhhgk F DL D RLNVLRQR --- ILAPLEE L F K SRKQ L GEKLL NK FSV F LKEIALTKNLQ D ------ 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 492 esleyfelpsq L M T QRD E L E L aglt EK A EE idq VW NGLIQ IL DDLV T V F DDQEMT L QQ FL DVFDI G LEQLEFVMI P Q T L D 571
Cdd:TIGR02774 482 ----------- L A T TLS E V E Q ---- EK Q EE --- VW KTFTD IL EQFA T I F GQEKLS L DD FL ALLHS G MSLSQYRTV P A T V D 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 572 Q V SIGTM DL AKVDNKKHI Y MV G MNDGIL P QTVSS SSL I TDEE KKYVE D ---- NA H VEL s PTSDI L QMDEAFVCYIAMTRS 647
Cdd:TIGR02774 544 V V TVKSY DL IEPHTAPFV Y AI G LTQSNF P KISQN SSL L TDEE RQNLN D atee GG H FDI - ASQEN L KKNHYTMLSLFNSAT 622
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 648 QQS V TFSYS L MGN S gd E KEI SP F L TQI ke LFYDLEIINLQDLHKAQPLLMMQHSHQTKIQLFE Y LR - G WLDHEDI D YRWL 726
Cdd:TIGR02774 623 KEL V LSAPQ L FNE S -- E DKE SP Y L QEL -- IDFGVPLREKGMNSLGEDKEDIGNYKALLSRVVA Y NQ q G EMEMTKQ D LTFW 698
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 727 DAYLAIRDDDQLN QGL DYL T ts L T YDNE T VQ L NEILS Q Q LY -- GKTINA S V S RFEGYQQCPFKHYASHG L R L N E RTKYEL 804
Cdd:TIGR02774 699 SVLVRYLRKKLDQ QGL EIP T -- I T DSLS T KT L SKDVL Q A LY pa DQPLKL S A S ALTTFYNNQYSYFLRYV L G L E E EESIHP 776
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 805 QNFDL G DIF H SVL - KYISDRIYGD F KNLDTKN I QSLTK E alelilp KVQFN L LNSS A YYK Y LSKKIGS I VET T LKA L KYQ 883
Cdd:TIGR02774 777 DARHH G NYL H RIF e RLMKLPGEES F DQKLNQA I NETSQ E ------- REFEA L YQED A EAR Y TLEILLD I ARS T API L RHN 849
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 884 geyskfvp QRFET g FRKSPKNK G ELVA Q PL I T N QG i P I NI RG Q IDRID TYTK G DH sy VNII DYKSS ESS at L D LTKV Y Y G 963
Cdd:TIGR02774 850 -------- SAIQV - IKEEENFG G KDNF Q LQ I D N GR - S I FV RG I IDRID RLSD G GS -- LGVV DYKSS ATQ -- F D IPHF Y N G 915
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 964 L QM Q MM TY MDIVLQNKERL G LTD I V kpg G LL Y F H VH EP RIKFKSWADI D e D QFQKDY i K NF K MS GL LNRDQE vldaldir 1043
Cdd:TIGR02774 916 L SP Q LP TY LAALKRIAPHE G EQP I F --- G AM Y L H MQ EP VQDLMAVKNL D - D AVVEAS - K AL K YQ GL FSEKEK -------- 982
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 1044 lepkynsdivpi ALT A K G AINQRSSKVA DE NIIY q L IEH NK KNFIET A SH I MD G HTEVA P 1103
Cdd:TIGR02774 983 ------------ SHL A E G YNKNKANLYS DE ELQL - L LDY NK YLYKKA A ET I LS G RFAIN P 1029
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
774-1004
5.81e-29
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 116.86
E-value: 5.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 774 S V SR F E G Y QQ CP FKHYASHG L R L ne R TKY EL QNF DLG DIF H SV L K yisd R I Y g DFKN L DTKNIQS L TKEA LE LIL P KV q F 853
Cdd:pfam12705 3 S P SR L E T Y LT CP LRFFLRYL L G L -- R EDE EL DAP DLG TLV H AA L E ---- R F Y - RWGR L PEEDLEE L LQAL LE ELW P EL - G 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 854 NLLNSSAYYKY L SKKIGSIV E TT L KA L KYQGEYS - K F V P QRF E T GF rkspknkgelvaqplitn Q G IPINIR G Q IDR I D T 932
Cdd:pfam12705 75 LQSEILPRLPW L AGRLRRRL E RM L RR L AEWLRAR r G F R P VAV E L GF ------------------ G G TTVRLV G R IDR V D L 136
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488428184 933 YTK G dhs Y VN IIDYK SSESSATLDLTKV Y Y GL qm Q MMT Y MDIVLQNKER LG ltdiv K P G G L LY FHVHE P RI K 1004
Cdd:pfam12705 137 DGE G --- Y LR IIDYK TGSAPPQSEDLDL Y E GL -- Q LLL Y LLALAAGEKA LG ----- G P A G A LY LRLDD P LK K 198
UvrD
COG0210 Superfamily I DNA or RNA helicase [Replication, recombination and repair];
84-680
1.27e-13
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain]
Cd Length: 721
Bit Score: 75.36
E-value: 1.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 84 E QR L SKA A LEMMI -- FH ----- I VQQ H ------ ESDLKLYGSQA Q Y --------- Y GL S EK ------ L AEQ I QDF K KYNV 135
Cdd:COG0210 72 E AL L GRL A RGLWV gt FH slalr I LRR H aellgl PPNFTILDGDD Q L rlikellke L GL D EK rfppre L LSL I SRA K NEGL 151
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 136 TPE H L NQ L IEN hsiqtrt KHKLEDISLI Y KQLES R M -- N G e FITTE D S L QQFIEI L SQSQWIKKAE ------ VFI D GFHN 207
Cdd:COG0210 152 TPE E L AE L LAA ------- DPEWRAAAEL Y EAYQE R L ra N N - ALDFD D L L LLAVRL L EENPEVLEKY qnrfry ILV D EYQD 223
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 208 FSTLE Y RIIEA L VQHAKQVT V -------------------- LLTT D - GSHHPFS L --- F R KPSEV L shle D I AN RL n I NL 263
Cdd:COG0210 224 TNPAQ Y ELLRL L AGDGRNLC V vgdddqsiygfrgadpenil RFEK D f PDAKVIK L eqn Y R STQNI L ---- D A AN AV - I AN 298
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 264 N KTYFN tfyrynnddl KNL engfdalq F T PKHHQNH V KIFESSSMR EE INE VA RR I l KDVR E ADYKFR DIA I LYR DESYA 343
Cdd:COG0210 299 N PGRLG ---------- KNL -------- W T DNGEGEK V RLYVAPDEE EE ARF VA DE I - RELH E EGVPLS DIA V LYR TNAQS 359
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 344 YLF E SI L PSYD IP FNIDTKKSMTHHPIMEM L RSL L EVIRSNWHIN A M LR lfktn V L T sqfkrssylidllenf V LE RGI y 423
Cdd:COG0210 360 RAL E EA L RRAG IP YRVVGGLRFYERAEIKD L LAY L RLLANPDDDV A L LR ----- I L N ---------------- V PR RGI - 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 424 G KRW L DE difs IDQFS R MGRK S hq L T E ghq AL YK -- E VIK L KKNVINKVLY F EQAMNEAHTVKDYA t SFY E S LE YFELP S 501
Cdd:COG0210 418 G AAT L ER ---- LREAA R EEGI S -- L L E --- AL RD lg E LAG L SGRAAKALRR F AELLEALRAAAERL - PLE E L LE ALLDE S 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 502 QL mtq RD EL E l AGLT E K AE E - IDQVW n G L IQILDDLVT vf DDQEMT L QQ FL DVFDIGLEQLE fvm IPQTL D Q V SIG T MDL 580
Cdd:COG0210 488 GY --- EE EL R - EEAG E E AE R r LENLE - E L VDAAARFEE -- RNPGAS L EA FL EELALLSDLDA --- ADEDE D A V TLM T LHA 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 581 AK ------ V dnkkhi YM VG MND G IL P qtv SSS SL ITD EE kkyvednahvelsptsdilq MD E AF - VC Y I A M TR SQQSVTF 653
Cdd:COG0210 558 AK glefpv V ------ FL VG LEE G LF P --- HQR SL DDE EE -------------------- LE E ER r LF Y V A I TR ARERLYL 608
650 660 670
....*....|....*....|....*....|
gi 488428184 654 S Y SLMGNSGD E K --- E I S P FL TQIK E LFYD 680
Cdd:COG0210 609 T Y AASRRLWG E T qdn E P S R FL DELP E ELLE 638
Slr0479
COG2887 RecB family exonuclease [Replication, recombination and repair];
774-1010
1.88e-08
RecB family exonuclease [Replication, recombination and repair];
Pssm-ID: 442133 [Multi-domain]
Cd Length: 248
Bit Score: 56.58
E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 774 S V SR F E GYQQ CP FKH YA SHG L R L NERTKYELQNF D L G DIF H S VL KYISDRIYGD fkn L DTKNIQS L TK EA LELILPK vqf 853
Cdd:COG2887 4 S P SR I E TLLR CP LRY YA RYI L G L RDPLEPPPDAA D R G TLV H A VL ERFYKLPADE --- L PAEELLA L LE EA WAELGFE --- 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 854 nlln SSAYYKYLSKKIGSIV E ttl KA L KYQGEYSKFV P QRF E TG F R kspknk G EL VA qplitnqgi PINI RG Q IDRID TY 933
Cdd:COG2887 78 ---- DPWAAALWLERAERLL E --- AF L EWERAPAGLE P VAV E VE F E ------ L EL PG --------- GVRL RG R IDRID RL 135
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488428184 934 TK G D hsy VNII DYK SSESSA T L D LT kvyy G LQM Q MMT Y MDIVLQNK E R L G ltdi VKPGG L L Y FHVHEPRIKFKSWAD 1010
Cdd:COG2887 136 PD G R --- LVVV DYK TGKAPS T K D EA ---- G EDP Q LAL Y ALALERGF E G L V ---- PAGAR L V Y LGDLGKKKVLDPLEE 201
UvrD_C
pfam13361 UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
300-656
1.88e-07
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain]
Cd Length: 377
Bit Score: 54.72
E-value: 1.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 300 V KI F E SSSMR EE INEV A RR I l K DVREA D Y K FR DIA I L Y R DE S Y A Y L F E SI L PSYD IP FN - IDTK K SMTHHP I MEM L r SL L 378
Cdd:pfam13361 46 I KI I E AETEE EE AEWI A LE I - K KLVAR D E K YN DIA V L T R SN S D A D L I E EA L KKLG IP YF v VGQT K FFRREE I KDI L - AY L 123
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 379 EV I RSNWHINAML R LFKT ---------- NVLTSQF KR SSY L I D LLENFV L ER G IYGKRW L DE D - I FSI D QFSR mgrkshq 447
Cdd:pfam13361 124 RL I ANKHDSISLK R ILNG pkrgignatl ERIREYK KR GLR L S D FINPDT L TY G DPFVIA L EQ D n I VVF D VETT ------- 196
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 448 lte G HQALYK E V I KLKKNVI NK vlyfe QAMNE ahtvkdyatsfy ES L E Y F --- EL P SQLMT Q ---- R DE LELAGLTEK AE 520
Cdd:pfam13361 197 --- G LDTTED E I I QIAAIKL NK ----- KGVVI ------------ ES F E R F lrl KK P VGDSL Q vhgf S DE FLQENGETP AE 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 521 EIDQVWN g LIQI L DD L VTVFDD --------- Q E MT L QQ FL DVFDIGLEQ LE FVM I pqt LDQVS I G T MDL AK --- V D N kkh 588
Cdd:pfam13361 257 ALRDFLE - KLEN L RE L YSILRE yddieetpe P E DA L RN FL EIATLSNSE LE GSD I --- KERIP I M T IHQ AK gle F D T --- 329
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488428184 589 IYMV G MND GI L P QTV S SSSL - ITD EE KK yvednahvelsptsdilqmdeaf VC Y I A M TR SQQSVTF SYS 656
Cdd:pfam13361 330 VFLA G LEE GI F P SYR S IKDE g NLE EE RR ----------------------- LF Y V A I TR AKKRLYI SYS 375
PRK10919
PRK10919 ATP-dependent DNA helicase Rep; Provisional
200-654
4.62e-06
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain]
Cd Length: 672
Bit Score: 50.99
E-value: 4.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 200 VFI D GFHNFS T LE Y RIIEA LV QHAKQV TV LLTT D G S HHPFSLF R KPSE VL SH l E D IANRLN I N L NKT Y FNT -- FYRYN N D 277
Cdd:PRK10919 211 LLV D EYQDTN T SQ Y ELVKL LV GSRARF TV VGDD D Q S IYSWRGA R PQNL VL LS - Q D FPALQV I K L EQN Y RSS gr ILKAA N I 289
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 278 DLK N LENG F DALQ F TPKHHQNHV K IFESSSMRE E INE V ARRILKD -- V READ YK fr D I AILYR DESYAYL FE SI L PSYD I 355
Cdd:PRK10919 290 LIA N NPHV F EKRL F SELGYGDEL K VLSANNEEH E AER V TGELIAH hf V NKTQ YK -- D Y AILYR GNHQSRV FE KF L MQNR I 367
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 356 P FN I DTKK S MTHH P IMEM L RSL L E V IRSNWHIN A M LR LFK T ----- NVL T S Q ------ FK R SSY L IDLLENFV L ERGIY G 424
Cdd:PRK10919 368 P YK I SGGT S FFSR P EIKD L LAY L R V LTNPDDDS A F LR IVN T pkrei GPA T L Q klgewa MT R NKS L FTASFDMG L SQTLS G 447
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 425 k R WLD edif S IDQ F SRMGRKSHQ L T E ghqaly K E VIKLKKNV I NKV lyfeqamneahtvk DY ATSF YE SL eyfel PS qlm 504
Cdd:PRK10919 448 - R GYE ---- S LTR F THWLAEIQR L A E ------ R E PVAAVRDL I HGI -------------- DY ESWL YE TS ----- PS --- 494
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488428184 505 tqrdelelaglt E KA E E ----- ID Q VWNGLIQI L -- DD L vtvfd D QE MTL Q Q FLDV F DI g LEQL E FVMIPQT LDQV SIG T 577
Cdd:PRK10919 495 ------------ P KA A E mrmkn VN Q LFSWMTEM L eg SE L ----- D EP MTL T Q VVTR F TL - RDMM E RGESEEE LDQV QLM T 556
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488428184 578 MDLA K VDNKKHI Y M VGM ND G I LP QTV S SSSLIT DEE KK yvednahvelsptsdilqmdeaf VC Y IAM TR S Q QSV TF S 654
Cdd:PRK10919 557 LHAS K GLEFPYV Y L VGM EE G L LP HQS S IDEDNI DEE RR ----------------------- LA Y VGI TR A Q KEL TF T 610
SF1_C_UvrD
cd18807 C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ...
300-350
3.17e-03
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain]
Cd Length: 150
Bit Score: 39.52
E-value: 3.17e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 488428184 300 V KIFESSSMRE E INEV A RR I LKDVREADYKFR DIAIL Y R DESY A YLF E SI L 350
Cdd:cd18807 34 V ELLLAKDEAD E AKAI A DE I KRLIESGPVQYS DIAIL V R TNRQ A RVI E EA L 84
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
