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Conserved domains on  [gi|488617877|ref|WP_002554726|]
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MULTISPECIES: polyprenyl diphosphate synthase [Pseudomonas]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
9-245 4.56e-152

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 423.31  E-value: 4.56e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:COG0020   92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDID 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQV 245
Cdd:COG0020  172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
9-245 4.56e-152

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 423.31  E-value: 4.56e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:COG0020   92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDID 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQV 245
Cdd:COG0020  172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 5-249 8.39e-131

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 369.78  E-value: 8.39e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   5 KPAVPSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELF 84
Cdd:PRK14836   7 MIPANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  85 FTALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQP 164
Cdd:PRK14836  87 LKALDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAP 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877 165 EDITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQ 244
Cdd:PRK14836 167 DEIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQ 246


                 ....*
gi 488617877 245 VEAGA 249
Cdd:PRK14836 247 IADRA 251
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 15-233 1.53e-128

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 362.46  E-value: 1.53e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  15 HVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETKR 94
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  95 LNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITPELLQT 174
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 488617877 175 CLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFAS 233
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 19-239 1.12e-123

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 350.13  E-value: 1.12e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   19 IMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFT-ALRRETKRLNE 97
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   98 NDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQagHLQPEDITPELLQTCLA 177
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488617877  178 TGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 14-239 3.16e-107

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 308.95  E-value: 3.16e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   14 RHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETK 93
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   94 RLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITPELLQ 173
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488617877  174 TCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
9-245 4.56e-152

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 423.31  E-value: 4.56e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:COG0020   12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:COG0020   92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDID 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQV 245
Cdd:COG0020  172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 5-249 8.39e-131

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 369.78  E-value: 8.39e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   5 KPAVPSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELF 84
Cdd:PRK14836   7 MIPANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  85 FTALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQP 164
Cdd:PRK14836  87 LKALDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAP 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877 165 EDITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQ 244
Cdd:PRK14836 167 DEIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQ 246


                 ....*
gi 488617877 245 VEAGA 249
Cdd:PRK14836 247 IADRA 251
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 15-233 1.53e-128

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 362.46  E-value: 1.53e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  15 HVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETKR 94
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  95 LNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITPELLQT 174
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 488617877 175 CLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFAS 233
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 19-239 1.12e-123

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 350.13  E-value: 1.12e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   19 IMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFT-ALRRETKRLNE 97
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   98 NDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQagHLQPEDITPELLQTCLA 177
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGK--KLDPEDIDEELISSHLY 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488617877  178 TGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 9-241 1.01e-114

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 328.76  E-value: 1.01e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:PRK14830  19 KGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:PRK14830  99 DKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPEDIT 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKT 241
Cdd:PRK14830 179 EELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFGGV 251
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 14-239 3.16e-107

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 308.95  E-value: 3.16e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   14 RHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETK 93
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   94 RLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITPELLQ 173
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488617877  174 TCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14834 PRK14834
isoprenyl transferase;
6-239 2.94e-100

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 292.04  E-value: 2.94e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   6 PAVPSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFF 85
Cdd:PRK14834   8 ESDAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  86 TALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPE 165
Cdd:PRK14834  88 LFIRRDLAELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPA 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488617877 166 DITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:PRK14834 168 SIDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 9-240 3.55e-100

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 291.85  E-value: 3.55e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:PRK14831  17 PQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:PRK14831  97 RRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEID 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGK 240
Cdd:PRK14831 177 ENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14838 PRK14838
isoprenyl transferase;
10-246 2.37e-95

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 279.45  E-value: 2.37e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  10 SSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALR 89
Cdd:PRK14838   8 NRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSIE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  90 RETkrLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITP 169
Cdd:PRK14838  88 EET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEITE 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488617877 170 ELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQVE 246
Cdd:PRK14838 166 ESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQIS 242
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
20-242 8.09e-94

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 275.32  E-value: 8.09e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  20 MDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETKRLNEND 99
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877 100 ISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDITPELLQTCLATG 179
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHICMH 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488617877 180 DLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTS 242
Cdd:PRK10240 161 ELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTE 223
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 9-247 2.68e-78

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 236.82  E-value: 2.68e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   9 PSSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTAL 88
Cdd:PRK14832  15 PQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  89 RRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDIT 168
Cdd:PRK14832  95 RRELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVN 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKTSEQVEA 247
Cdd:PRK14832 175 EQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQVKALIPA 253
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
10-239 2.04e-75

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 228.54  E-value: 2.04e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  10 SSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALR 89
Cdd:PRK14833   2 DNTLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  90 RETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLArEVQAGHLQPEDITP 169
Cdd:PRK14833  82 DERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLL-ESPPSHIGELESLE 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877 170 ELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:PRK14833 161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
15-239 1.10e-73

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 224.25  E-value: 1.10e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  15 HVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRETKR 94
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETER 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  95 LNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAqrlarevqAGHLQPEDITPELLQT 174
Cdd:PRK14839  92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAA--------AKALGPEGLSREAFSD 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488617877 175 cLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:PRK14839 164 -LLTGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 11-240 8.87e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 222.41  E-value: 8.87e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  11 SVPRHVAIIMDGNNRWAKK----RLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFT 86
Cdd:PRK14840  17 SLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  87 ALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPED 166
Cdd:PRK14840  97 QLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488617877 167 ITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGK 240
Cdd:PRK14840 177 ISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 6-241 5.47e-67

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 207.33  E-value: 5.47e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   6 PAVPS-SVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELF 84
Cdd:PRK14829   7 PDIPKnKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  85 FTALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQP 164
Cdd:PRK14829  87 RDVIHRRREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISG 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488617877 165 EDITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGKT 241
Cdd:PRK14829 167 DRVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 6-240 2.86e-64

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 202.49  E-value: 2.86e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877   6 PAVPSS-VPRHVAIIMDGNNRWAKKRLLPGVAGHKAGvDAVraVIEV-CA--EAKVEVLTLFAFSSENWQRPAEEVGALM 81
Cdd:PRK14827  60 PRIPADrLPNHVAIVMDGNGRWATQRGLARTEGHKMG-EAV--VIDIaCGaiELGIKWLSLYAFSTENWKRSPEEVRFLM 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  82 ELFFTALRRETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGH 161
Cdd:PRK14827 137 GFNRDVVRRRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGR 216

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488617877 162 LQPEDITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGK 240
Cdd:PRK14827 217 LNPERITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 12-239 9.50e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 196.36  E-value: 9.50e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  12 VPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRE 91
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  92 TKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGhlQPEDITPEL 171
Cdd:PRK14841  83 MELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQG--KKIELTEET 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488617877 172 LQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDF-KHDAMRaALADFASRQRRFG 239
Cdd:PRK14841 161 FRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFtKRDFLR-AIESYSKRERRFG 228
PRK14835 PRK14835
isoprenyl transferase;
12-240 1.81e-61

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 194.29  E-value: 1.81e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  12 VPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRR- 90
Cdd:PRK14835  41 LPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREARRm 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  91 -ETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPEDI-- 167
Cdd:PRK14835 121 aVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKSPEEVaa 200

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488617877 168 --TPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGK 240
Cdd:PRK14835 201 elTPEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 12-240 1.60e-55

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 178.40  E-value: 1.60e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  12 VPRHVAIIMDGNNRWAKKRLLPGVA-GHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRR 90
Cdd:PRK14828  26 VPGHVGIIVDGNRRWARKAGFTDVSqGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIEDVVRQ 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  91 ETKrlnENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPED---- 166
Cdd:PRK14828 106 LAP---DGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSIDElaes 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488617877 167 ITPELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKH-DAMRaALADFASRQRRFGK 240
Cdd:PRK14828 183 VTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKvDFLR-ALRDYSQRERRFGK 256
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 10-239 5.91e-55

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 176.72  E-value: 5.91e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  10 SSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALR 89
Cdd:PRK14842   6 STIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFIE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  90 RETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAAQRLAREVQAGHLQPED-IT 168
Cdd:PRK14842  86 TRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTLEKpLK 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488617877 169 PELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFG 239
Cdd:PRK14842 166 EKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 10-240 4.91e-48

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 158.45  E-value: 4.91e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  10 SSVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALR 89
Cdd:PRK14837   4 NSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  90 RETKRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGGQWDIAQAaqrlAREVQAGHLQPEDITP 169
Cdd:PRK14837  84 SEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRA----VKKFLSSGLDLETLNE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488617877 170 ELLQTCLATGDLPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHDAMRAALADFASRQRRFGK 240
Cdd:PRK14837 160 NVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFGR 230
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 14-219 4.85e-25

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 100.84  E-value: 4.85e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  14 RHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAKVEVLTLFAFSSENWQRPAEEVGALMELFFTALRRET- 92
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLNLLILINEDf 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877  93 --KRLNENDISLRIIGDRSRFHPELQAAMREAEVRTSGNSRFVLQIAANYGG-----------------------QWDIA 147
Cdd:PTZ00349 101 ffKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSrnemslckfnpnlyfdtyknlleEKKIL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488617877 148 QAAQRLAREVQAGHLQPEDITPEL---------------------------------------LQTCLATGDLPLPDLCI 188
Cdd:PTZ00349 181 CGSNILTDPIKEGTFAIPDDEDECdyldheleneridldlkfdgdcicgeksflneeqieivnYHKKLLTSDLPPPNILI 260

                        250       260       270
                 ....*....|....*....|....*....|..
gi 488617877 189 RTGGEHRISNFLLWQLA-YAELYFSDLFWPDF 219
Cdd:PTZ00349 261 RTSGEKRLSDFMLYQISeFTEIYFINEYWPIF 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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