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Conserved domains on  [gi|488868637|ref|WP_002780876|]
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MULTISPECIES: DUF2018 family protein [Campylobacter]

Protein Classification

DUF2018 family protein( domain architecture ID 10559577)

DUF2018 family protein similar to Helicobacter pylori protein Hp0242

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2018 pfam09442
Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological ...
 8-84 1.32e-19

Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological significance when H.pylori colonizes the human stomach, which adopts a unique four alpha-helical triangular conformations. The biologically active form is thought to be a tetramer. The protein is expressed along with six other proteins, some of which are related to iron storage and haem biosynthesis.


:

Pssm-ID: 430614  Cd Length: 83  Bit Score: 75.01  E-value: 1.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488868637   8 FNKTPKEKFIEIIQNGNLGALEKVFENFFADHIAMIELLEKQGFN---EMDMKSFILENGDFIQERQNDLFIELGAKILG 84
Cdd:pfam09442  1 FEGTPKSKFFDIIFHANRTIVEKELEKLLERLAALELLLEKQGLEekyEKEIKNYILENQDEIEARKNDLYIESMGNILS 80
 
Name Accession Description Interval E-value
DUF2018 pfam09442
Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological ...
 8-84 1.32e-19

Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological significance when H.pylori colonizes the human stomach, which adopts a unique four alpha-helical triangular conformations. The biologically active form is thought to be a tetramer. The protein is expressed along with six other proteins, some of which are related to iron storage and haem biosynthesis.


Pssm-ID: 430614  Cd Length: 83  Bit Score: 75.01  E-value: 1.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488868637   8 FNKTPKEKFIEIIQNGNLGALEKVFENFFADHIAMIELLEKQGFN---EMDMKSFILENGDFIQERQNDLFIELGAKILG 84
Cdd:pfam09442  1 FEGTPKSKFFDIIFHANRTIVEKELEKLLERLAALELLLEKQGLEekyEKEIKNYILENQDEIEARKNDLYIESMGNILS 80
 
Name Accession Description Interval E-value
DUF2018 pfam09442
Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological ...
 8-84 1.32e-19

Domain of unknown function (DUF2018); Acid-adaptive protein possibly of physiological significance when H.pylori colonizes the human stomach, which adopts a unique four alpha-helical triangular conformations. The biologically active form is thought to be a tetramer. The protein is expressed along with six other proteins, some of which are related to iron storage and haem biosynthesis.


Pssm-ID: 430614  Cd Length: 83  Bit Score: 75.01  E-value: 1.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488868637   8 FNKTPKEKFIEIIQNGNLGALEKVFENFFADHIAMIELLEKQGFN---EMDMKSFILENGDFIQERQNDLFIELGAKILG 84
Cdd:pfam09442  1 FEGTPKSKFFDIIFHANRTIVEKELEKLLERLAALELLLEKQGLEekyEKEIKNYILENQDEIEARKNDLYIESMGNILS 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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