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Conserved domains on  [gi|488943964|ref|WP_002855039|]
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MULTISPECIES: membrane protein [Campylobacter]

Protein Classification

LptA/OstA family protein( domain architecture ID 229796)

LptA/OstA family protein similar to Haemophilus influenzae lipopolysaccharide export system protein LptA involved in the assembly of lipopolysaccharide (LPS)

Gene Ontology:  GO:0017089|GO:0001530|GO:0043165|GO:0015920
PubMed:  21169485
TCDB:  1.B.42

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LptA super family cl43566
Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];
82-165 4.49e-05

Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG1934:

Pssm-ID: 441537 [Multi-domain]  Cd Length: 164  Bit Score: 41.44  E-value: 4.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488943964  82 DFNLSANRLEFF---NKDMSKVLFEGNVTYI----GSNNVKIISQEVEYQPKDKILHTNTNFKALINGSIINGNTLNYDV 154
Cdd:COG1934   54 TLTLRADKLVVYydkAGGIERIEATGNVTFRqkrdGGQEVEATADRAEYDVATDTVVLTGNAVLTQGGNTVTGDRITYDL 133

                         90
                 ....*....|.
gi 488943964 155 KNKILNIQGVN 165
Cdd:COG1934  134 KTGRATAEGGG 144
 
Name Accession Description Interval E-value
LptA COG1934
Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];
82-165 4.49e-05

Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441537 [Multi-domain]  Cd Length: 164  Bit Score: 41.44  E-value: 4.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488943964  82 DFNLSANRLEFF---NKDMSKVLFEGNVTYI----GSNNVKIISQEVEYQPKDKILHTNTNFKALINGSIINGNTLNYDV 154
Cdd:COG1934   54 TLTLRADKLVVYydkAGGIERIEATGNVTFRqkrdGGQEVEATADRAEYDVATDTVVLTGNAVLTQGGNTVTGDRITYDL 133

                         90
                 ....*....|.
gi 488943964 155 KNKILNIQGVN 165
Cdd:COG1934  134 KTGRATAEGGG 144
LptC_YrbK TIGR04409
LPS export ABC transporter periplasmic protein LptC; Members of this family are LptC, a ...
 94-163 8.46e-03

LPS export ABC transporter periplasmic protein LptC; Members of this family are LptC, a periplasmic protein tethered to the inner membrane in the lipopolysaccharide (LPS)exporter transenvelope complex (Lpt), which is responsible for conducting LPS to the outer leaflet of the outer membrane in most Gram-negative bacteria. LptC is homologous to LptA, another member of the transenvelope complex. Genes lptC and lptA are often adjacent. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275202 [Multi-domain]  Cd Length: 180  Bit Score: 35.30  E-value: 8.46e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488943964   94 NKDMSKVLFEGNV----TYIGSNNVKIISQEVEYQPKDKILHTNTNFKALINGSIINGNTLNYDVKNKILNIQG 163
Cdd:TIGR04409 101 NKDGKELYLYGNVrvtrLAGDGPPQTLTTENLTVDLDTQDATSDQPVTITGPGFTITGVGMKANLKTGTAELLS 174
 
Name Accession Description Interval E-value
LptA COG1934
Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];
82-165 4.49e-05

Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441537 [Multi-domain]  Cd Length: 164  Bit Score: 41.44  E-value: 4.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488943964  82 DFNLSANRLEFF---NKDMSKVLFEGNVTYI----GSNNVKIISQEVEYQPKDKILHTNTNFKALINGSIINGNTLNYDV 154
Cdd:COG1934   54 TLTLRADKLVVYydkAGGIERIEATGNVTFRqkrdGGQEVEATADRAEYDVATDTVVLTGNAVLTQGGNTVTGDRITYDL 133

                         90
                 ....*....|.
gi 488943964 155 KNKILNIQGVN 165
Cdd:COG1934  134 KTGRATAEGGG 144
LptC_YrbK TIGR04409
LPS export ABC transporter periplasmic protein LptC; Members of this family are LptC, a ...
 94-163 8.46e-03

LPS export ABC transporter periplasmic protein LptC; Members of this family are LptC, a periplasmic protein tethered to the inner membrane in the lipopolysaccharide (LPS)exporter transenvelope complex (Lpt), which is responsible for conducting LPS to the outer leaflet of the outer membrane in most Gram-negative bacteria. LptC is homologous to LptA, another member of the transenvelope complex. Genes lptC and lptA are often adjacent. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275202 [Multi-domain]  Cd Length: 180  Bit Score: 35.30  E-value: 8.46e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488943964   94 NKDMSKVLFEGNV----TYIGSNNVKIISQEVEYQPKDKILHTNTNFKALINGSIINGNTLNYDVKNKILNIQG 163
Cdd:TIGR04409 101 NKDGKELYLYGNVrvtrLAGDGPPQTLTTENLTVDLDTQDATSDQPVTITGPGFTITGVGMKANLKTGTAELLS 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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