|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
2-432 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 868.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 2 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 81
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 KEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADK 161
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 162 LKEVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 241
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 242 SNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQ 321
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 322 INSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQ 401
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 488974773 402 RIEELTGVPVDIISTGPDRTETMILRDPFDA 432
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-427 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 810.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 4 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 83
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 84 MKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLK 163
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 164 EVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 324 SLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRI 403
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 488974773 404 EELTGVPVDIISTGPDRTETMILR 427
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
6-424 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 757.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 85
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKEV 165
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 166 MEYHNFQLVNFYKaEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 246 AGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 326 SGFCLTKLDVLDGLKEVKICVGYRmPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIEE 405
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 488974773 406 LTGVPVDIISTGPDRTETM 424
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-425 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 745.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 4 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 83
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 84 MKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARgakaIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLK 163
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 164 EVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 324 SLSGFCLTKLDVLDGLKEVKICVGYRmPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRI 403
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 488974773 404 EELTGVPVDIISTGPDRTETMI 425
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-431 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 717.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 85
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKEV 165
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 166 MEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 246 AGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 326 SGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIEE 405
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 488974773 406 LTGVPVDIISTGPDRTETMILRDPFD 431
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-425 |
9.81e-180 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 503.57 E-value: 9.81e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 82
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 83 EMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDlfdkatfadkl 162
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 163 kevmeyhnfqlvnfykaeavdyqkvlddvmaiadiltSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 243 NTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 323 NSLSGFCLTKLDVldglkevkicvgyrmpdgrevtttplaadnwegiepiyetmpgwsettfgvkersglpqAALNYIQR 402
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 488974773 403 IEELTGVPVDIISTGPDRTETMI 425
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
6-323 |
3.75e-34 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 129.03 E-value: 3.75e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILREN-VTSIIGNGVVLSPAALM 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 KEMKGLEDRGIPVRERLLLSE-ACPLILDYHValdvaREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFAD 160
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 161 KLKEVMEYHnfqlvnfykAEAVDYQkvlddvmaiadiltsmvvdvsdLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT 240
Cdd:NF038379 157 VRDQPWEIA---------ERVVDNA----------------------LYDFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 241 SSNTTAGGVATGSGLGPRYVDY--VLGIIKAYSTRVGA-----GPFPTEL-FDETGeflckQGNEFGATTGRRRRTGWLD 312
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 488974773 313 AVAVRRAVQIN 323
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
2-432 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 868.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 2 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 81
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 KEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADK 161
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 162 LKEVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 241
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 242 SNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQ 321
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 322 INSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQ 401
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 488974773 402 RIEELTGVPVDIISTGPDRTETMILRDPFDA 432
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-427 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 810.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 4 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 83
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 84 MKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLK 163
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 164 EVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 324 SLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRI 403
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 488974773 404 EELTGVPVDIISTGPDRTETMILR 427
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
6-424 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 757.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 85
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKEV 165
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 166 MEYHNFQLVNFYKaEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 246 AGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 326 SGFCLTKLDVLDGLKEVKICVGYRmPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIEE 405
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 488974773 406 LTGVPVDIISTGPDRTETM 424
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-425 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 745.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 4 NVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 83
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 84 MKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARgakaIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLK 163
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 164 EVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 324 SLSGFCLTKLDVLDGLKEVKICVGYRmPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRI 403
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 488974773 404 EELTGVPVDIISTGPDRTETMI 425
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-431 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 717.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 85
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKEV 165
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 166 MEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 246 AGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 326 SGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIEE 405
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 488974773 406 LTGVPVDIISTGPDRTETMILRDPFD 431
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-427 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 562.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 1 MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRENVTSIIGNGVVLSPAA 79
Cdd:PLN02513 1 LSQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNEKTTCVIGNGVVVHLPG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 80 LMKEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFA 159
Cdd:PLN02513 81 LFEEIDGLESNGVSCEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 160 DKLKEVMEYHNFQLVNF-YKAEAVDYQkvLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPY 238
Cdd:PLN02513 161 EKLRELLADAAARFEGFeYDASMVEEE--VEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 239 VTSSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRR 318
Cdd:PLN02513 239 VTSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 319 AVQINSLSGFCLTKLDVLDGLKEVKICVGYRMPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALN 398
Cdd:PLN02513 319 SCQINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQA 398
|
410 420
....*....|....*....|....*....
gi 488974773 399 YIQRIEELTGVPVDIISTGPDRTETMILR 427
Cdd:PLN02513 399 YVERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
2-428 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 513.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 2 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 81
Cdd:PTZ00350 12 SKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 KEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVARE--KARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFA 159
Cdd:PTZ00350 92 EEIEQLTKKGINLLGRLYISDRAHLVFDLHQAIDGIQEseKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 160 DKLKEVMEYHNFQlvnfYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYV 239
Cdd:PTZ00350 172 KKYRKLVEKLQEQ----YNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 240 TSSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PTZ00350 248 TSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMP-DGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALN 398
Cdd:PTZ00350 328 QMINGFDSINLTKLDVLSGLKEIKICVNYKNKgTGLEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420 430
....*....|....*....|....*....|
gi 488974773 399 YIQRIEELTGVPVDIISTGPDRtETMILRD 428
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNR-ENMIVKK 436
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-425 |
9.81e-180 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 503.57 E-value: 9.81e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 82
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 83 EMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDlfdkatfadkl 162
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 163 kevmeyhnfqlvnfykaeavdyqkvlddvmaiadiltSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 243 NTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 323 NSLSGFCLTKLDVldglkevkicvgyrmpdgrevtttplaadnwegiepiyetmpgwsettfgvkersglpqAALNYIQR 402
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 488974773 403 IEELTGVPVDIISTGPDRTETMI 425
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
6-426 |
3.97e-145 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 420.13 E-value: 3.97e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMK 85
Cdd:PRK13787 5 LVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGA-KAIGTTGRGIGPAYEDKVARRGLRVGDLFDKaTFADKLKE 164
Cdd:PRK13787 85 RLQKEGFPVKDKLLLSDACHLLFPYHSQIDSARETTSSQeHKIGTTKKGIGICYADKMMRTGLRVGDLLDK-SYKRRLKH 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 165 VMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNT 244
Cdd:PRK13787 164 LVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 245 TAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINS 324
Cdd:PRK13787 244 TTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSVRING 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 325 LSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPlaADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIE 404
Cdd:PRK13787 324 ITSIALTKIDILSDYDTIPVAVGYKL-NGKTLDCFP--SQGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYISALE 400
|
410 420
....*....|....*....|..
gi 488974773 405 ELTGVPVDIISTGPDRTETMIL 426
Cdd:PRK13787 401 KWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
5-423 |
1.09e-135 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 395.33 E-value: 1.09e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 5 VVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEM 84
Cdd:PRK13788 4 IAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 85 KGLEDRGIPvrERLLLSEACPLILDYHVALDvarekARGaKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKE 164
Cdd:PRK13788 84 ENLRAGGLN--PKLLISERAHLVLPHHKYVD-----GRK-NFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERVER 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 165 VMEyhnfQLVNFYKAEAVD-YQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:PRK13788 156 LLE----AKPNSTREAGWDtVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSSH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQG----NEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PRK13788 232 PTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKYA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRmPDGRevtttplaadnwegiePIYETMPGWSETTfGVKERSGLPQAALNY 399
Cdd:PRK13788 312 CEVNGFDGLVLTKLDVLSGLEKVKVCVEYD-DDGQ----------------PVYKELPGWGDLD-GVKSREALPKEAQAY 373
|
410 420
....*....|....*....|....
gi 488974773 400 IQRIEELTGVPVDIISTGPDRTET 423
Cdd:PRK13788 374 LELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
3-425 |
1.86e-134 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 392.16 E-value: 1.86e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 82
Cdd:PRK13783 1 MKRVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 83 EMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGaKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKL 162
Cdd:PRK13783 81 ELEELKEKFPDYSGRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 163 KEVMEYHNfqlvNFYKAEaVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGdfVMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:PRK13783 160 EKILSLYK----KLYGIE-FDVEKMMEDLLTFYEKIKDLVVSPVEIKRILEEKS--VLFEGTQGVLLDLDVGTYPYVTSS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 243 NTTAGGVATGSGLgPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:PRK13783 233 NCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 323 NSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVtTTPLAADNWEGIEPIYETMPGWSETTfgvkersglPQAALNYIQR 402
Cdd:PRK13783 312 SGVDSLVMTKADVLNGFEKIKVCVRYEI-GGKEV-RDPSSLRDLEKAEPVYEEFDGWKSLE---------DKNFLKFVDF 380
|
410 420
....*....|....*....|...
gi 488974773 403 IEELTGVPVDIISTGPdRTETMI 425
Cdd:PRK13783 381 IERETGRKIAYISTGP-KIEEIV 402
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
6-423 |
3.44e-132 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 387.23 E-value: 3.44e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILReNVTSIIGNGVVLSPAALMKEMK 85
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLL-DARVLIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 86 GLEDRGIPVR-ERLLLSEACPLILDYHVALDVAREKARGAKaIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKE 164
Cdd:PRK13786 83 MLEKHGVKVDaEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 165 VMEyhnfQLVNFYKAEAVDYQKV-----LDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYV 239
Cdd:PRK13786 162 LAP----QKEKEIKELGGDPSIVrdealIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 240 TSSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PRK13786 238 TSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTP-LAADNWEgIEPIYETMPGWSETTFGVKERSGLPQAALN 398
Cdd:PRK13786 318 IYLNGYTEIALTKLDVLTGLDPIKICVGYEL-DGEILDYPPeLTSDLAR-CVPVYEELEGWSTDLTEVKAYEDLPENARN 395
|
410 420
....*....|....*....|....*
gi 488974773 399 YIQRIEELTGVPVDIISTGPDRTET 423
Cdd:PRK13786 396 YVERLEELMGVPIKYISVGPGREQT 420
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
3-430 |
7.71e-125 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 368.58 E-value: 7.71e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMK 82
Cdd:PRK13784 2 SNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 83 EMKGLEDRGIPVR-ERLLLSEACPLILDYHVALDVAREKARGAKaIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADK 161
Cdd:PRK13784 82 EITRLQAKGIAISaENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 162 LKEVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTS 241
Cdd:PRK13784 161 LAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 242 SNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQ 321
Cdd:PRK13784 241 SNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 322 INSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEgIEPIYETMPGWSETTFGVKErsGLPQAALNYIQ 401
Cdd:PRK13784 321 CSNLTSIALTKVDVLSDMDTLKVCIGYKY-EGKEIYCAYPGIDLYK-VEPILVEMEPFSIDETVTKD--NMPAALKTYLK 396
|
410 420
....*....|....*....|....*....
gi 488974773 402 RIEELTGVPVDIISTGPDRTETMILRDPF 430
Cdd:PRK13784 397 TIENHVGIPISSLAYGPSREQILFFEDYF 425
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
5-430 |
7.41e-122 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 361.77 E-value: 7.41e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 5 VVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVtSIIGNGVVLSPAALMKEM 84
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKI-GVLGNGCVVNPETLFDEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 85 KGLEDRGIPVRERLllSEACPLILDYHVALDVARE--KARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKL 162
Cdd:PRK13785 82 DALRERGLDPDVRV--AERAHVILPYHRVLDGIEEeaKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 163 KEVMEYHNFQLVNFY------KAEAVDYQKVLDDVMAIADILTS--MVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHG 234
Cdd:PRK13785 160 EYVVPQKRALAEDVYgldaseTPEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 235 TYPYVTSSNTTAGGVATGSGLGPRYVDY--VLGIIKAYSTRVGAGPFPTEL---------------FDETGEFLCKQGNE 297
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 298 FGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREVTTTPLAADNWEGIEPIYETMP 377
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYEL-DGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 488974773 378 GWSETTFGVKERSG---LPQAALNYIQRIEELTGVPVDIISTGPDRTETMILRDPF 430
Cdd:PRK13785 399 GWPEVDWAAVAEEGydaLPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
6-427 |
2.44e-90 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 276.76 E-value: 2.44e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLL--TERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKE 83
Cdd:PRK04293 5 IVVGGFFGDEGKGKIIAYLalKDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLLKE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 84 MKGLEdrgipVRERLLLSEACPLILDYHVALDvaREKARGAKAIGTTGRGIGPAYEDKVARRGlrvgdlfdkatfadKLk 163
Cdd:PRK04293 85 VEELN-----VGGRVFVDYRCGIIEEKHVEED--RSDEHLSKKIGSTGTGCGPANADRVLRRL--------------KL- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 164 evmeyhnfqlvnfykaeAVDYqkvlddvmaiaDILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:PRK04293 143 -----------------AKDV-----------EELEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVTSKD 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 244 TTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEflcKQG-NEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:PRK04293 195 TTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAE---KLGlVEYGTVTGRRRRVGPFDFELARRAARI 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 323 NSLSGFCLTKLDVLDglKEVkicvgyrmpdgrevtttplaadnwegiepiyetmpgwsettFGVKERSGLPQAALNYIQR 402
Cdd:PRK04293 272 NGATQIAITKLDKLD--KEA-----------------------------------------YGVTEYDKLPPEAKKFIEE 308
|
410 420
....*....|....*....|....*
gi 488974773 403 IEELTGVPVDIISTGPDRTETMILR 427
Cdd:PRK04293 309 IEEELGVPVTLISTGPELEDTIDLR 333
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
6-323 |
3.75e-34 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 129.03 E-value: 3.75e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 6 VVLGTQWGDEGKGKIVDLLTERAKYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILREN-VTSIIGNGVVLSPAALM 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 KEMKGLEDRGIPVRERLLLSE-ACPLILDYHValdvaREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFAD 160
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 161 KLKEVMEYHnfqlvnfykAEAVDYQkvlddvmaiadiltsmvvdvsdLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT 240
Cdd:NF038379 157 VRDQPWEIA---------ERVVDNA----------------------LYDFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 241 SSNTTAGGVATGSGLGPRYVDY--VLGIIKAYSTRVGA-----GPFPTEL-FDETGeflckQGNEFGATTGRRRRTGWLD 312
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 488974773 313 AVAVRRAVQIN 323
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
5-427 |
1.98e-28 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 118.23 E-value: 1.98e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 5 VVVLGTQWGDEGKGKIVDLLTER--AKYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRENVTSIIGNGVVLSPAALM 81
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 82 -KEMKGLEDRGIPVRERLLLSEACpLILDYHVALDVArekarGAKAIGTTGRGIGPAYEDKVARRGLRVGDLF-DKATFA 159
Cdd:PTZ00351 252 eKEIIQLIDAGIDYRDRLFIGNVC-IVTPYHKLLDLL-----GSAANSSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLR 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 160 DKLKEVMEYH----------NFQLVNFYKAEAVD-YQKVLDDVMAIA------DILTSMV-------------VDVSDLL 209
Cdd:PTZ00351 326 KRLEKDMDTYlgllkvknlsDADVVRLCREENSDgVVRVPDYVIAFAqakdkvEFLVKLYrdrvrhnpdfparCDVTYEL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 210 DQARQRGDFVMFEGAQGTLL-DIDHGTYPYVTSSNTTAGGVATGSGLG-PRYVDYVLGIIKAY-STRVGAG--------- 277
Cdd:PTZ00351 406 HAAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNfQKFKSVVLNVHKAPgSSRVGIGacpssfvpq 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 278 ----------------------------------PF------------PTELFDETGEF---------LCKQGNEFGATT 302
Cdd:PTZ00351 486 dyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYnigvamaiaSAQHHGECGAVT 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974773 303 GRRRRTGWLDAVAVRravQINSLSGFCLT--KLDVLDGLKEVKICVGYRM--PDGREVTTTPLAADNWEGI--------- 369
Cdd:PTZ00351 566 KKPRVCGFFDCVLQH---EVNSIQGPYLTisALDRGDEYDKVGVTIAYVYynPEGKQVDVNGHVYKNGDIIragdpvpse 642
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488974773 370 ------EPIYETMPGWSETTFGVKER---SGLPQAALNYIQRIEELTGVPVDIISTGPDRTETMILR 427
Cdd:PTZ00351 643 palyhcHPIVKLIDGWRDNPIAAAKRrrnAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLR 709
|
|
| |
