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Conserved domains on  [gi|488977027|ref|WP_002887899|]
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MULTISPECIES: FtsW/RodA/SpoVE family cell cycle protein [Campylobacter]

Protein Classification

FtsW/RodA/SpoVE family cell cycle protein( domain architecture ID 10020374)

FtsW/RodA/SpoVE family cell cycle protein such as rod shape-determining protein RodA, a peptidoglycan polymerase that is essential for cell wall elongation

EC:  2.4.1.129
Gene Ontology:  GO:0008955|GO:0008360
PubMed:  2509435

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
rodA_shape TIGR02210
rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family ...
13-358 1.15e-115

rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


:

Pssm-ID: 274033  Cd Length: 352  Bit Score: 339.87  E-value: 1.15e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   13 DYMQPILFLPIILISFFLIFEANP----FLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFGVE 88
Cdd:TIGR02210   1 DWGLLLLVLLLVGIGLLVLYSASGgslaPFALKQLVWFGIGLVLMIIVALIDYRFLRRLAYPLYVLGLLLLVAVLLFGTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   89 KLGAKRWLEIPFTHFtiQPSEIFKPSFILMLAYLIYQNPPPKnGYKLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVG 168
Cdd:TIGR02210  81 GKGAQRWIDLGFFRL--QPSEFAKLALILMLAKYLSRRPLDK-PPRLKDLLKALILILVPALLILKQPDLGTALVVLAIG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  169 FGVLFIMGVHYKIWLSIVIAISVSSP-IIYTHLLKPYQKQRIHDFIS-----EKPSYQVTQSMIAIGNGGLTGKSQDEAT 242
Cdd:TIGR02210 158 LFVLFLAGLSWKLILGLLAAGAAAIPvIIWWFLLHDYQKQRILTFLDpesdpLGAGYHIIQSKIAIGSGGLFGKGWLQGT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  243 QTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKdDYFARVAINCVALFIFIYAAVNISMTIGF 322
Cdd:TIGR02210 238 QSQLEFLPEQHTDFIFSVLAEEFGFVGGLVLLLLYLLLILRGLRIALNAK-DRFGRLLAGGIALTFFFYVFVNIGMVIGL 316
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 488977027  323 APVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRY 358
Cdd:TIGR02210 317 LPVVGIPLPLVSYGGSSLLTLMIGFGLLMSIHTHRR 352
 
Name Accession Description Interval E-value
rodA_shape TIGR02210
rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family ...
13-358 1.15e-115

rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274033  Cd Length: 352  Bit Score: 339.87  E-value: 1.15e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   13 DYMQPILFLPIILISFFLIFEANP----FLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFGVE 88
Cdd:TIGR02210   1 DWGLLLLVLLLVGIGLLVLYSASGgslaPFALKQLVWFGIGLVLMIIVALIDYRFLRRLAYPLYVLGLLLLVAVLLFGTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   89 KLGAKRWLEIPFTHFtiQPSEIFKPSFILMLAYLIYQNPPPKnGYKLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVG 168
Cdd:TIGR02210  81 GKGAQRWIDLGFFRL--QPSEFAKLALILMLAKYLSRRPLDK-PPRLKDLLKALILILVPALLILKQPDLGTALVVLAIG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  169 FGVLFIMGVHYKIWLSIVIAISVSSP-IIYTHLLKPYQKQRIHDFIS-----EKPSYQVTQSMIAIGNGGLTGKSQDEAT 242
Cdd:TIGR02210 158 LFVLFLAGLSWKLILGLLAAGAAAIPvIIWWFLLHDYQKQRILTFLDpesdpLGAGYHIIQSKIAIGSGGLFGKGWLQGT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  243 QTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKdDYFARVAINCVALFIFIYAAVNISMTIGF 322
Cdd:TIGR02210 238 QSQLEFLPEQHTDFIFSVLAEEFGFVGGLVLLLLYLLLILRGLRIALNAK-DRFGRLLAGGIALTFFFYVFVNIGMVIGL 316
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 488977027  323 APVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRY 358
Cdd:TIGR02210 317 LPVVGIPLPLVSYGGSSLLTLMIGFGLLMSIHTHRR 352
FtsW COG0772
Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome ...
1-351 3.14e-91

Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440535  Cd Length: 371  Bit Score: 278.14  E-value: 3.14e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   1 MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAE-----------KQFVYACVGLFAFMVFFFFPIRKFIWIIP 69
Cdd:COG0772    2 ALGLLLRRLRKIDWLLLLLVLLLLGIGLVMVYSASSALAArkggdpfyffkRQLIWLLLGLVLMLVVSRIDYRRLRRLAY 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  70 VAYWINIFLLLSVDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIYQNPppKNGYKLKQFIKLSFYIILPF 149
Cdd:COG0772   82 PLYLLGLVLLLLVLLFGTEVNGARRWISLGG--FSFQPSEFAKLALILFLASYLSRKR--DKLKDLKGLLPPLLLIGLPV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 150 LLIAKEPDLGSAMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSSPIIYthLLKPYQKQRIHDFIS-----EKPSYQVTQS 224
Cdd:COG0772  158 GLILLQPDLGTALVLFAIFLGMLFVAGLPWKYLLGLLLLGVAAAVLLI--LLKPYQRARILAFLDpwadpLGAGYQIIQS 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 225 MIAIGNGGLTGKSQDEATQtHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDdYFARVAINCV 304
Cdd:COG0772  236 LIAIGSGGLFGKGLGNGTQ-KLGYLPEAHTDFIFAVIGEELGFIGALLVLLLFLLLIYRGLRIALRARD-PFGRLLAAGI 313
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 488977027 305 ALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQ 351
Cdd:COG0772  314 ASLIFFQAFINIGMVTGLLPVTGVPLPFISYGGSSLLANMIALGLLL 360
FTSW_RODA_SPOVE pfam01098
Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE
2-358 4.14e-75

Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE


Pssm-ID: 426047  Cd Length: 356  Bit Score: 236.39  E-value: 4.14e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027    2 FRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLS 81
Cdd:pfam01098   1 RRLLFIVLLLLGALGLVMVYSASAVTSLVLFGDSFFFFKRQLVYLLLGFIAFWVLLRIPLRFLRKWAFYLFIIGLLLLVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   82 VDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIYQNPPPKNGYkLKQFIKLSFYIILPFLLIAKEPDLGSA 161
Cdd:pfam01098  81 VFVIGPSANGAKRWIRLGG--FSIQPSEFMKIALTLFLAAYLSRKPDNVRPR-LRGFLPPLVIIALAAGLILLQPDLGTA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  162 MVLLLVGFGVLFIMGVhyKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKP-----SYQVTQSMIAIGNGGLTGK 236
Cdd:pfam01098 158 VLLGIILLVMLFLSGL--SWRLFIALVLIGVSPIVWLILLEDYQIKRVTSFLDPFKdplgsGYQIIQSLIAIGSGGIFGK 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  237 SQDEATQtHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINcVALFIFIYAAVNI 316
Cdd:pfam01098 236 GLGNGQQ-KLGYLPEAHTDFIFAVIGEELGFVGVLILLALFGLLIYRGLRIARRARDRFGSLLAVG-ISLLIFIQSFINI 313
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 488977027  317 SMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRY 358
Cdd:pfam01098 314 GMVSGLLPVTGLPLPFFSYGGSSLLATLALFGILLNISRELR 355
PRK10794 PRK10794
rod shape-determining protein RodA;
10-357 2.07e-54

rod shape-determining protein RodA;


Pssm-ID: 182737  Cd Length: 370  Bit Score: 183.01  E-value: 2.07e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  10 THFDYMQPILFLPIILISFFLIFEA---NPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFG 86
Cdd:PRK10794  14 IHIDPTMLLIILALLVYSALVIWSAsgqDIGMMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  87 VEKLGAKRWLEIPFTHFtiQPSEIFKPSFILMLAYLIYQNPPPKNgykLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLL 166
Cdd:PRK10794  94 QISKGAQRWLDLGIVRF--QPSEIAKIAVPLMVARFINRDVCPPS---LKNTAIALVLIFMPTLLVAAQPDLGTSILVAL 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 167 VGFGVLFIMGVHYKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEK-----PSYQVTQSMIAIGNGGLTGKSQDEA 241
Cdd:PRK10794 169 SGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPEsdplgAGYHIIQSKIAIGSGGLRGKGWLHG 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 242 TQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDyFARVAINCVALFIFIYAAVNISMTIG 321
Cdd:PRK10794 249 TQSQLEFLPERHTDFIFAVLAEELGLVGVLILLALYILLIMRGLWIAARAQTT-FGRVMAGGLMLILFVYVFVNIGMVSG 327
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 488977027 322 FAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFR 357
Cdd:PRK10794 328 ILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHR 363
RodA_shape NF037961
rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE ...
70-347 1.03e-34

rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE superfamily. It has been reported that RodA proteins play important roles in maintaining cell shape and antibiotic resistance in bacteria.


Pssm-ID: 411566  Cd Length: 415  Bit Score: 131.94  E-value: 1.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  70 VAYWINIFLLLSVDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIyqNPPPKNGYKLKQFIKLSFYIILPF 149
Cdd:NF037961  69 IIYIISLLSLLGLFIFGKTINGATSWYAIGG--FTLQPSEFAKAATALALAKYL--SDIQTDIKRFKDQLKAFAIILIPA 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 150 LLIAKEPDLGSAMV----------------LLLVGF--------------------GVLFIMGVHYK------------I 181
Cdd:NF037961 145 ILILLQPDAGSALVyfafffvlyreglpliYLIIGFilillfvltlkfgpiwvliiAALLIFLYYFLkkkkkppilkiiI 224
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 182 WLSIVIAISVSSPIIYTHLLKPYQKQRI------------HDFISEKPSYQVTQSMIAIGNGGLTGKSQDEATQTHFKFL 249
Cdd:NF037961 225 ILLICILFSFSVNFVYDNVLEQHHRDRFslwlglekdpekLEQMKKTIGYNTNQSEKAISSGGFTGKGFLEGTRTKGNFV 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 250 PISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDyFARVAINCVALFIFIYAAVNISMTIGFAPVVGIP 329
Cdd:NF037961 305 PEQHTDYIFSTVGEEWGFLGSSLVVLLFVLLLLRIIYLAERQKSQ-FSRVYGYSVASILFIHFFINIGMVIGLIPTIGIP 383
                        330       340
                 ....*....|....*....|.
gi 488977027 330 LPFFSYGGSS---FTIFMIFF 347
Cdd:NF037961 384 LPFFSYGGSGlwgFTILLFIF 404
 
Name Accession Description Interval E-value
rodA_shape TIGR02210
rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family ...
13-358 1.15e-115

rod shape-determining protein RodA; This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274033  Cd Length: 352  Bit Score: 339.87  E-value: 1.15e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   13 DYMQPILFLPIILISFFLIFEANP----FLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFGVE 88
Cdd:TIGR02210   1 DWGLLLLVLLLVGIGLLVLYSASGgslaPFALKQLVWFGIGLVLMIIVALIDYRFLRRLAYPLYVLGLLLLVAVLLFGTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   89 KLGAKRWLEIPFTHFtiQPSEIFKPSFILMLAYLIYQNPPPKnGYKLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVG 168
Cdd:TIGR02210  81 GKGAQRWIDLGFFRL--QPSEFAKLALILMLAKYLSRRPLDK-PPRLKDLLKALILILVPALLILKQPDLGTALVVLAIG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  169 FGVLFIMGVHYKIWLSIVIAISVSSP-IIYTHLLKPYQKQRIHDFIS-----EKPSYQVTQSMIAIGNGGLTGKSQDEAT 242
Cdd:TIGR02210 158 LFVLFLAGLSWKLILGLLAAGAAAIPvIIWWFLLHDYQKQRILTFLDpesdpLGAGYHIIQSKIAIGSGGLFGKGWLQGT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  243 QTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKdDYFARVAINCVALFIFIYAAVNISMTIGF 322
Cdd:TIGR02210 238 QSQLEFLPEQHTDFIFSVLAEEFGFVGGLVLLLLYLLLILRGLRIALNAK-DRFGRLLAGGIALTFFFYVFVNIGMVIGL 316
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 488977027  323 APVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRY 358
Cdd:TIGR02210 317 LPVVGIPLPLVSYGGSSLLTLMIGFGLLMSIHTHRR 352
FtsW COG0772
Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome ...
1-351 3.14e-91

Peptodoglycan polymerase FtsW/RodA/SpoVE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440535  Cd Length: 371  Bit Score: 278.14  E-value: 3.14e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   1 MFRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAE-----------KQFVYACVGLFAFMVFFFFPIRKFIWIIP 69
Cdd:COG0772    2 ALGLLLRRLRKIDWLLLLLVLLLLGIGLVMVYSASSALAArkggdpfyffkRQLIWLLLGLVLMLVVSRIDYRRLRRLAY 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  70 VAYWINIFLLLSVDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIYQNPppKNGYKLKQFIKLSFYIILPF 149
Cdd:COG0772   82 PLYLLGLVLLLLVLLFGTEVNGARRWISLGG--FSFQPSEFAKLALILFLASYLSRKR--DKLKDLKGLLPPLLLIGLPV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 150 LLIAKEPDLGSAMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSSPIIYthLLKPYQKQRIHDFIS-----EKPSYQVTQS 224
Cdd:COG0772  158 GLILLQPDLGTALVLFAIFLGMLFVAGLPWKYLLGLLLLGVAAAVLLI--LLKPYQRARILAFLDpwadpLGAGYQIIQS 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 225 MIAIGNGGLTGKSQDEATQtHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDdYFARVAINCV 304
Cdd:COG0772  236 LIAIGSGGLFGKGLGNGTQ-KLGYLPEAHTDFIFAVIGEELGFIGALLVLLLFLLLIYRGLRIALRARD-PFGRLLAAGI 313
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 488977027 305 ALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQ 351
Cdd:COG0772  314 ASLIFFQAFINIGMVTGLLPVTGVPLPFISYGGSSLLANMIALGLLL 360
FTSW_RODA_SPOVE pfam01098
Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE
2-358 4.14e-75

Cell cycle protein; This entry includes the following members; FtsW, RodA, SpoVE


Pssm-ID: 426047  Cd Length: 356  Bit Score: 236.39  E-value: 4.14e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027    2 FRLDRRILTHFDYMQPILFLPIILISFFLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLS 81
Cdd:pfam01098   1 RRLLFIVLLLLGALGLVMVYSASAVTSLVLFGDSFFFFKRQLVYLLLGFIAFWVLLRIPLRFLRKWAFYLFIIGLLLLVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   82 VDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIYQNPPPKNGYkLKQFIKLSFYIILPFLLIAKEPDLGSA 161
Cdd:pfam01098  81 VFVIGPSANGAKRWIRLGG--FSIQPSEFMKIALTLFLAAYLSRKPDNVRPR-LRGFLPPLVIIALAAGLILLQPDLGTA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  162 MVLLLVGFGVLFIMGVhyKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEKP-----SYQVTQSMIAIGNGGLTGK 236
Cdd:pfam01098 158 VLLGIILLVMLFLSGL--SWRLFIALVLIGVSPIVWLILLEDYQIKRVTSFLDPFKdplgsGYQIIQSLIAIGSGGIFGK 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  237 SQDEATQtHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINcVALFIFIYAAVNI 316
Cdd:pfam01098 236 GLGNGQQ-KLGYLPEAHTDFIFAVIGEELGFVGVLILLALFGLLIYRGLRIARRARDRFGSLLAVG-ISLLIFIQSFINI 313
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 488977027  317 SMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFRY 358
Cdd:pfam01098 314 GMVSGLLPVTGLPLPFFSYGGSSLLATLALFGILLNISRELR 355
PRK10794 PRK10794
rod shape-determining protein RodA;
10-357 2.07e-54

rod shape-determining protein RodA;


Pssm-ID: 182737  Cd Length: 370  Bit Score: 183.01  E-value: 2.07e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  10 THFDYMQPILFLPIILISFFLIFEA---NPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFG 86
Cdd:PRK10794  14 IHIDPTMLLIILALLVYSALVIWSAsgqDIGMMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  87 VEKLGAKRWLEIPFTHFtiQPSEIFKPSFILMLAYLIYQNPPPKNgykLKQFIKLSFYIILPFLLIAKEPDLGSAMVLLL 166
Cdd:PRK10794  94 QISKGAQRWLDLGIVRF--QPSEIAKIAVPLMVARFINRDVCPPS---LKNTAIALVLIFMPTLLVAAQPDLGTSILVAL 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 167 VGFGVLFIMGVHYKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFISEK-----PSYQVTQSMIAIGNGGLTGKSQDEA 241
Cdd:PRK10794 169 SGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPEsdplgAGYHIIQSKIAIGSGGLRGKGWLHG 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 242 TQTHFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDyFARVAINCVALFIFIYAAVNISMTIG 321
Cdd:PRK10794 249 TQSQLEFLPERHTDFIFAVLAEELGLVGVLILLALYILLIMRGLWIAARAQTT-FGRVMAGGLMLILFVYVFVNIGMVSG 327
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 488977027 322 FAPVVGIPLPFFSYGGSSFTIFMIFFGILQHLITFR 357
Cdd:PRK10794 328 ILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHR 363
ftsW TIGR02614
cell division protein FtsW; This family consists of FtsW, an integral membrane protein with ...
37-350 6.72e-54

cell division protein FtsW; This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division]


Pssm-ID: 274232  Cd Length: 356  Bit Score: 181.22  E-value: 6.72e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   37 FLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFGV--EKLGAKRWLEIPFthFTIQPSEIFKPS 114
Cdd:TIGR02614  36 YFLKRQLFYALLGLILMFVASRLPLRFWRKLSVPILLIAIVLLVLVLIPGIgkEVNGARRWIGLGG--FSIQPSEFAKLA 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  115 FILMLAYLIYQNPPPKNgyKLKQFIKLSFYIILPF-LLIAKEPDLGSAMVLLLVGFGVLFIMGVHYKIWLSIVIAISVSS 193
Cdd:TIGR02614 114 LIIYLAWYLARKQKEVK--SFLKFLPPLAVLGLLVgLLLLLQPDFGTTVVIFFITLGMLFLAGAPLRYFALLLLLGLLGG 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  194 PIIYTHllKPYQKQRIHDFIS-----EKPSYQVTQSMIAIGNGGLTGKSQDEATQTHFkFLPISTSDFIFAYMIERFGFI 268
Cdd:TIGR02614 192 AILIVS--SPYRMRRILSFLDpwadpFGSGYQLTQSLIALGSGGLFGVGLGNSVQKLF-YLPEAHTDFIFAVIGEELGFI 268
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  269 GGLTLIIFYILLIFHLLSLNYKLkDDYFARVAINCVALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMIFFG 348
Cdd:TIGR02614 269 GVLIVILLFAFLVWRGLRIALRA-EDLFGRYLAAGITIWIGLQAFINIGVVLGLLPTKGLTLPFISYGGSSLVATMIAIG 347

                  ..
gi 488977027  349 IL 350
Cdd:TIGR02614 348 LL 349
spoVE TIGR02615
stage V sporulation protein E; This model represents an exception within the members of the ...
29-350 2.49e-36

stage V sporulation protein E; This model represents an exception within the members of the FtsW model TIGR02614. This exception occurs only in endospore-forming genera such as Bacillus, Geobacillus, and Oceanobacillus. Like FtsW, members are found in a peptidoglycan operon context, but in these genera they part of a larger set of paralogs (not just the pair FtsW and RodA) and are required specifically for sporulation, not for viability. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination]


Pssm-ID: 131664  Cd Length: 354  Bit Score: 134.90  E-value: 2.49e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027   29 FLIFEANPFLAEKQFVYACVGLFAFMVFFFFPIRKFIWIIPVAYWINIFLLLSVDIFGV--EKLGAKRWLEIpfTHFTIQ 106
Cdd:TIGR02615  28 EYKFNDSFYFLKRQLLWAILGVFAMFFTMNIDYHTWKRWAKMLMVICFVLLLLVLIPGVgmERNGARRWIGV--GAFSIQ 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  107 PSEIFKPSFILMLAYLIYQNPPPKNGYKlKQFIKLSFYIILPFLLIAKEPDLGSAMVLLLVGFGVLFIMGVhyKIWLSIV 186
Cdd:TIGR02615 106 PSEIAKYALIIYLAKSLSEKQEYITSFR-KGVIPYLLLAGFAFGLIMLQPNLSTATVIVMVCFIMLFVAGA--RLSHFIA 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  187 IAISVSSPIIYTHLLKPYQKQRIHDFIS-----EKPSYQVTQSMIAIGNGGLTGKSQDEATQTHFkFLPISTSDFIFAYM 261
Cdd:TIGR02615 183 LVGIGISGGVALILSAPFRIGRILSFLNpwedpLGSGYQIIQSLYALGSGGLFGVGLGQSRQKCF-YLPEPHNDFIFAII 261
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  262 IERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDYFARVAINCVALfIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFT 341
Cdd:TIGR02615 262 GEELGLIGGTFIILLFVILLWRGIRIALKAPDLFGTLLAVGITSM-IGIQAMINIAVVTGSIPVTGVTLPFISYGGSSLT 340

                  ....*....
gi 488977027  342 IFMIFFGIL 350
Cdd:TIGR02615 341 LMMMAVGIL 349
RodA_shape NF037961
rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE ...
70-347 1.03e-34

rod shape-determining protein RodA; Proteins of this family are members of the FtsW/RodA/SpoVE superfamily. It has been reported that RodA proteins play important roles in maintaining cell shape and antibiotic resistance in bacteria.


Pssm-ID: 411566  Cd Length: 415  Bit Score: 131.94  E-value: 1.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  70 VAYWINIFLLLSVDIFGVEKLGAKRWLEIPFthFTIQPSEIFKPSFILMLAYLIyqNPPPKNGYKLKQFIKLSFYIILPF 149
Cdd:NF037961  69 IIYIISLLSLLGLFIFGKTINGATSWYAIGG--FTLQPSEFAKAATALALAKYL--SDIQTDIKRFKDQLKAFAIILIPA 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 150 LLIAKEPDLGSAMV----------------LLLVGF--------------------GVLFIMGVHYK------------I 181
Cdd:NF037961 145 ILILLQPDAGSALVyfafffvlyreglpliYLIIGFilillfvltlkfgpiwvliiAALLIFLYYFLkkkkkppilkiiI 224
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 182 WLSIVIAISVSSPIIYTHLLKPYQKQRI------------HDFISEKPSYQVTQSMIAIGNGGLTGKSQDEATQTHFKFL 249
Cdd:NF037961 225 ILLICILFSFSVNFVYDNVLEQHHRDRFslwlglekdpekLEQMKKTIGYNTNQSEKAISSGGFTGKGFLEGTRTKGNFV 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 250 PISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYKLKDDyFARVAINCVALFIFIYAAVNISMTIGFAPVVGIP 329
Cdd:NF037961 305 PEQHTDYIFSTVGEEWGFLGSSLVVLLFVLLLLRIIYLAERQKSQ-FSRVYGYSVASILFIHFFINIGMVIGLIPTIGIP 383
                        330       340
                 ....*....|....*....|.
gi 488977027 330 LPFFSYGGSS---FTIFMIFF 347
Cdd:NF037961 384 LPFFSYGGSGlwgFTILLFIF 404
PRK10774 PRK10774
cell division protein FtsW; Provisional
68-345 1.26e-24

cell division protein FtsW; Provisional


Pssm-ID: 182719  Cd Length: 404  Bit Score: 103.71  E-value: 1.26e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027  68 IPVAYW---------INIFLLLSVDIFGVEKLGAKRWleIPFTHFTIQPSEIFKPSFILMLA-YLIYQNPPPKNgyKLKQ 137
Cdd:PRK10774  92 LPMEFWqrysatmllGSIIMLLIVLVVGSSVNGASRW--IALGPLRIQPAELTKLSLFCYLAnYLVRKVDEVRN--NFWG 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 138 FIK-LSFYIILPFLLIAkEPDLGSAMVLLLVGFGVLFIMGVhyKIWLSIVIAISVSSPIIYTHLLKPYQKQRIHDFIS-- 214
Cdd:PRK10774 168 FLKpMGVMLVLAVLLLA-QPDLGTVVVLFVTTLAMLFLAGA--KLWQFIAIIGMGISAVVLLILAEPYRIRRVTSFWNpw 244
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488977027 215 EKP---SYQVTQSMIAIGNGGLTGKSQDEATQThFKFLPISTSDFIFAYMIERFGFIGGLTLIIFYILLIFHLLSLNYK- 290
Cdd:PRK10774 245 EDPfgsGYQLTQSLMAFGRGELWGQGLGNSVQK-LEYLPEAHTDFIFSIIGEELGYIGVVLALLMVFFVAFRAMSIGRKa 323
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488977027 291 -LKDDYFARVAINCVALFIFIYAAVNISMTIGFAPVVGIPLPFFSYGGSSFTIFMI 345
Cdd:PRK10774 324 lEIDQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMST 379
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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