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Conserved domains on  [gi|488978853|ref|WP_002889702|]
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MULTISPECIES: Na(+)-translocating NADH-quinone reductase subunit A [Klebsiella]

Protein Classification

NADH:ubiquinone reductase (Na(+)-transporting) subunit A( domain architecture ID 11480784)

NADH:ubiquinone reductase (Na(+)-transporting) subunit A is a component of the NQR complex that catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK05352 PRK05352
Na(+)-translocating NADH-quinone reductase subunit A; Provisional
1-447 0e+00

Na(+)-translocating NADH-quinone reductase subunit A; Provisional


:

Pssm-ID: 235426 [Multi-domain]  Cd Length: 448  Bit Score: 845.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   1 MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:PRK05352   2 MIKIKKGLDLPIAGAPEQVIEDGPAPKTVALLGEDYVGLRPKMKVKEGDKVKKGQPLFEDKKNPGVKFTSPASGTVVAIN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  81 RGERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:PRK05352  82 RGERRVLQSVVIEVEGDEQVTFEKYDAKDLASLSREQVKENLLESGLWTALRTRPFSKVPAPDSTPRAIFVTAMDTNPLA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:PRK05352 162 ADPEVIIAEQEEAFQAGLTVLSRLTDGKVHVCKAPGASLPGENLKNVEVHTFSGPHPAGLVGTHIHFLDPVSAGKTVWTI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 241 NYQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHGPHAFLGRF 320
Cdd:PRK05352 242 GYQDVIAIGKLFLTGELYTERVVALAGPAVKKPRLVRTRLGASLSELTAGELKAGDNRVISGSVLTGRTAKGPHAYLGRY 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 321 HLQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDLLA 400
Cdd:PRK05352 322 HNQVSVLPEGRERELFGWLRPGFNKFSVTRTYLSHLFKKKLFNFTTNTNGSERAMVPIGNYERVMPLDILPTQLLRALIV 401
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 488978853 401 GDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQEG 447
Cdd:PRK05352 402 GDTDEAQALGALELDEEDLALCTFVCPGKYEYGPILRDGLDRIEKEG 448
 
Name Accession Description Interval E-value
PRK05352 PRK05352
Na(+)-translocating NADH-quinone reductase subunit A; Provisional
1-447 0e+00

Na(+)-translocating NADH-quinone reductase subunit A; Provisional


Pssm-ID: 235426 [Multi-domain]  Cd Length: 448  Bit Score: 845.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   1 MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:PRK05352   2 MIKIKKGLDLPIAGAPEQVIEDGPAPKTVALLGEDYVGLRPKMKVKEGDKVKKGQPLFEDKKNPGVKFTSPASGTVVAIN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  81 RGERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:PRK05352  82 RGERRVLQSVVIEVEGDEQVTFEKYDAKDLASLSREQVKENLLESGLWTALRTRPFSKVPAPDSTPRAIFVTAMDTNPLA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:PRK05352 162 ADPEVIIAEQEEAFQAGLTVLSRLTDGKVHVCKAPGASLPGENLKNVEVHTFSGPHPAGLVGTHIHFLDPVSAGKTVWTI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 241 NYQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHGPHAFLGRF 320
Cdd:PRK05352 242 GYQDVIAIGKLFLTGELYTERVVALAGPAVKKPRLVRTRLGASLSELTAGELKAGDNRVISGSVLTGRTAKGPHAYLGRY 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 321 HLQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDLLA 400
Cdd:PRK05352 322 HNQVSVLPEGRERELFGWLRPGFNKFSVTRTYLSHLFKKKLFNFTTNTNGSERAMVPIGNYERVMPLDILPTQLLRALIV 401
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 488978853 401 GDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQEG 447
Cdd:PRK05352 402 GDTDEAQALGALELDEEDLALCTFVCPGKYEYGPILRDGLDRIEKEG 448
NqrA COG1726
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA [Energy production and ...
2-446 0e+00

Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA [Energy production and conversion]; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA is part of the Pathway/BioSystem: Na+-translocating NADH dehydrogenase


Pssm-ID: 441332 [Multi-domain]  Cd Length: 445  Bit Score: 832.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   2 IKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIHR 81
Cdd:COG1726    1 IKIKKGLDLPIKGAPEQVIEDGPASKTVALLGEDYVGMKPKMLVKEGDRVKAGQPLFEDKKNPGVKFTSPVSGTVVEINR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  82 GERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLAA 161
Cdd:COG1726   81 GEKRVLLSVVIEVDGDEQETFEKFGASDLASLSREQVKENLLESGLWTAIRQRPFSKVAAPDSTPKAIFVSAMDTNPLAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 162 EPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHLN 241
Cdd:COG1726  161 DPEVIIAGQEEAFQAGLTALSKLTDGKVHVCVAPGSSLPFAGLKGVEVHTFSGPHPAGLVGTHIHFLDPVNKGETVWTIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 242 YQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHGPHAFLGRFH 321
Cdd:COG1726  241 YQDVIAIGKLFLTGKLDTERVVALAGPEVKKPRYVRTRLGASLDELVAGELKDGENRVISGSVLTGRKATGPDGYLGRYH 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 322 LQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDLLAG 401
Cdd:COG1726  321 NQVSVLPEGREREFLGWLRPGFNKFSVTRAYLSWLFPKKKFDFTTNTNGSERAMVPTGNYEKVMPLDILPTQLLKALIAG 400
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 488978853 402 DTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQE 446
Cdd:COG1726  401 DTDEAEALGCLELDEEDLALCTFVCPSKYEYGPILREGLDLIEKE 445
nqrA TIGR01936
NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; This model represents the NqrA ...
2-447 0e+00

NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; This model represents the NqrA subunit of the six-protein, Na(+)-pumping NADH-quinone reductase of a number of marine and pathogenic Gram-negative bacteria. This oxidoreductase complex functions primarily as a sodium ion pump. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273885 [Multi-domain]  Cd Length: 447  Bit Score: 631.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853    2 IKITKGLDLPIAGMPLQQ-ISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:TIGR01936   1 ITIKKGLDLPLKGKPPEQgIAEKADPPTVAVDGRDFVGMRPKMKVRPGDKVKAGQPLFEDKKNPGVKFTSPVSGEVVAIN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   81 RGERRVLQSVVIDIEGNdaVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:TIGR01936  81 RGAKRVLLSVVIKKDGD--GEFATFPTYDLQTLSAEQIKENLLESGLWTAIKQRPFDIVATPDSSPRDIFITAADTRPLA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:TIGR01936 159 PDPEVVLAEFSSAFVVGLDALAKLFTGKVHVCKKDRLSLPTQLLSNAEIHTFSGPHPAGLPGTHIHFIAPIGNGKVVWTL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  241 NYQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQ-EGENRVISGSVLSGARAHGPHAFLGR 319
Cdd:TIGR01936 239 NYQDVIAIGHLFLTGELLTERVIALAGPAVKKPRYVRTTKGANLSQLFPGELTsEGENRLISGSVLTGRKAKKEEAYLGR 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  320 FHLQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFF-KRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDL 398
Cdd:TIGR01936 319 RDLQISVLPEGDVRELFGWLRPGLNKYSVTRTYLSGLFkKRKEYNMDTNTNGGERAMIPIGIYERVMPLDIPPTLLLKAL 398
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 488978853  399 LAGDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQEG 447
Cdd:TIGR01936 399 IAGDFDKAQRLGALEVDEEDFALCTFVDPSKYEYGSIVRESLDRIEKEG 447
NQRA pfam05896
Na(+)-translocating NADH-quinone reductase subunit A (NQRA); This family consists of several ...
1-257 8.59e-161

Na(+)-translocating NADH-quinone reductase subunit A (NQRA); This family consists of several bacterial Na(+)-translocating NADH-quinone reductase subunit A (NQRA) proteins. The Na(+)-translocating NADH: ubiquinone oxidoreductase (Na(+)-NQR) generates an electrochemical Na(+) potential driven by aerobic respiration.


Pssm-ID: 461773  Cd Length: 257  Bit Score: 453.97  E-value: 8.59e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853    1 MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:pfam05896   1 MIKIKKGLDLPIKGAPEQVIEDGPAVTRVALLGEDYVGLKPKMKVKEGDKVKAGQVLFEDKKNPGVKFTSPASGTVVAIN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   81 RGERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:pfam05896  81 RGAKRVLQSVVIEVDGDEQITFEKFGAKDLASLSREQVKENLLASGLWTALRTRPFSKVPAPDSTPKAIFVTAMDTNPLA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:pfam05896 161 ADPEVIIAGQEEAFQAGLTALSKLTDGKVHVCKAPGSALPLADLANVEIHEFSGPHPAGLVGTHIHFIDPVNAGKTVWTI 240
                         250
                  ....*....|....*..
gi 488978853  241 NYQDAIAIGKLFLDGEL 257
Cdd:pfam05896 241 NYQDVIAIGKLFLTGEL 257
 
Name Accession Description Interval E-value
PRK05352 PRK05352
Na(+)-translocating NADH-quinone reductase subunit A; Provisional
1-447 0e+00

Na(+)-translocating NADH-quinone reductase subunit A; Provisional


Pssm-ID: 235426 [Multi-domain]  Cd Length: 448  Bit Score: 845.23  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   1 MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:PRK05352   2 MIKIKKGLDLPIAGAPEQVIEDGPAPKTVALLGEDYVGLRPKMKVKEGDKVKKGQPLFEDKKNPGVKFTSPASGTVVAIN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  81 RGERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:PRK05352  82 RGERRVLQSVVIEVEGDEQVTFEKYDAKDLASLSREQVKENLLESGLWTALRTRPFSKVPAPDSTPRAIFVTAMDTNPLA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:PRK05352 162 ADPEVIIAEQEEAFQAGLTVLSRLTDGKVHVCKAPGASLPGENLKNVEVHTFSGPHPAGLVGTHIHFLDPVSAGKTVWTI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 241 NYQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHGPHAFLGRF 320
Cdd:PRK05352 242 GYQDVIAIGKLFLTGELYTERVVALAGPAVKKPRLVRTRLGASLSELTAGELKAGDNRVISGSVLTGRTAKGPHAYLGRY 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 321 HLQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDLLA 400
Cdd:PRK05352 322 HNQVSVLPEGRERELFGWLRPGFNKFSVTRTYLSHLFKKKLFNFTTNTNGSERAMVPIGNYERVMPLDILPTQLLRALIV 401
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 488978853 401 GDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQEG 447
Cdd:PRK05352 402 GDTDEAQALGALELDEEDLALCTFVCPGKYEYGPILRDGLDRIEKEG 448
NqrA COG1726
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA [Energy production and ...
2-446 0e+00

Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA [Energy production and conversion]; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA is part of the Pathway/BioSystem: Na+-translocating NADH dehydrogenase


Pssm-ID: 441332 [Multi-domain]  Cd Length: 445  Bit Score: 832.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   2 IKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIHR 81
Cdd:COG1726    1 IKIKKGLDLPIKGAPEQVIEDGPASKTVALLGEDYVGMKPKMLVKEGDRVKAGQPLFEDKKNPGVKFTSPVSGTVVEINR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  82 GERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLAA 161
Cdd:COG1726   81 GEKRVLLSVVIEVDGDEQETFEKFGASDLASLSREQVKENLLESGLWTAIRQRPFSKVAAPDSTPKAIFVSAMDTNPLAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 162 EPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHLN 241
Cdd:COG1726  161 DPEVIIAGQEEAFQAGLTALSKLTDGKVHVCVAPGSSLPFAGLKGVEVHTFSGPHPAGLVGTHIHFLDPVNKGETVWTIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 242 YQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHGPHAFLGRFH 321
Cdd:COG1726  241 YQDVIAIGKLFLTGKLDTERVVALAGPEVKKPRYVRTRLGASLDELVAGELKDGENRVISGSVLTGRKATGPDGYLGRYH 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 322 LQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFFKRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDLLAG 401
Cdd:COG1726  321 NQVSVLPEGREREFLGWLRPGFNKFSVTRAYLSWLFPKKKFDFTTNTNGSERAMVPTGNYEKVMPLDILPTQLLKALIAG 400
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 488978853 402 DTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQE 446
Cdd:COG1726  401 DTDEAEALGCLELDEEDLALCTFVCPSKYEYGPILREGLDLIEKE 445
nqrA TIGR01936
NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; This model represents the NqrA ...
2-447 0e+00

NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; This model represents the NqrA subunit of the six-protein, Na(+)-pumping NADH-quinone reductase of a number of marine and pathogenic Gram-negative bacteria. This oxidoreductase complex functions primarily as a sodium ion pump. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273885 [Multi-domain]  Cd Length: 447  Bit Score: 631.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853    2 IKITKGLDLPIAGMPLQQ-ISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:TIGR01936   1 ITIKKGLDLPLKGKPPEQgIAEKADPPTVAVDGRDFVGMRPKMKVRPGDKVKAGQPLFEDKKNPGVKFTSPVSGEVVAIN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   81 RGERRVLQSVVIDIEGNdaVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:TIGR01936  81 RGAKRVLLSVVIKKDGD--GEFATFPTYDLQTLSAEQIKENLLESGLWTAIKQRPFDIVATPDSSPRDIFITAADTRPLA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:TIGR01936 159 PDPEVVLAEFSSAFVVGLDALAKLFTGKVHVCKKDRLSLPTQLLSNAEIHTFSGPHPAGLPGTHIHFIAPIGNGKVVWTL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  241 NYQDAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLLAGELQ-EGENRVISGSVLSGARAHGPHAFLGR 319
Cdd:TIGR01936 239 NYQDVIAIGHLFLTGELLTERVIALAGPAVKKPRYVRTTKGANLSQLFPGELTsEGENRLISGSVLTGRKAKKEEAYLGR 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  320 FHLQVSVVKEGREKELFGWVMPGKEKFSITRTTLGHFF-KRKRFHFSTDTNGGERAMVPIGNYERVMPLDILPTILLRDL 398
Cdd:TIGR01936 319 RDLQISVLPEGDVRELFGWLRPGLNKYSVTRTYLSGLFkKRKEYNMDTNTNGGERAMIPIGIYERVMPLDIPPTLLLKAL 398
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 488978853  399 LAGDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPALRSVLTRIEQEG 447
Cdd:TIGR01936 399 IAGDFDKAQRLGALEVDEEDFALCTFVDPSKYEYGSIVRESLDRIEKEG 447
NQRA pfam05896
Na(+)-translocating NADH-quinone reductase subunit A (NQRA); This family consists of several ...
1-257 8.59e-161

Na(+)-translocating NADH-quinone reductase subunit A (NQRA); This family consists of several bacterial Na(+)-translocating NADH-quinone reductase subunit A (NQRA) proteins. The Na(+)-translocating NADH: ubiquinone oxidoreductase (Na(+)-NQR) generates an electrochemical Na(+) potential driven by aerobic respiration.


Pssm-ID: 461773  Cd Length: 257  Bit Score: 453.97  E-value: 8.59e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853    1 MIKITKGLDLPIAGMPLQQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIH 80
Cdd:pfam05896   1 MIKIKKGLDLPIKGAPEQVIEDGPAVTRVALLGEDYVGLKPKMKVKEGDKVKAGQVLFEDKKNPGVKFTSPASGTVVAIN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   81 RGERRVLQSVVIDIEGNDAVAFTRYAADALAELPRDTVQQQLLASGQWTALRTRPFSKTPLPGSTPAAIFVNAMDTNPLA 160
Cdd:pfam05896  81 RGAKRVLQSVVIEVDGDEQITFEKFGAKDLASLSREQVKENLLASGLWTALRTRPFSKVPAPDSTPKAIFVTAMDTNPLA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  161 AEPQPIILAERAAFDAGLTVLTRLTDGKVHVCQPSGGKLGGHPLGQVCFNQFSGPHPAGLPGTHIHFLEPVSLNKQVWHL 240
Cdd:pfam05896 161 ADPEVIIAGQEEAFQAGLTALSKLTDGKVHVCKAPGSALPLADLANVEIHEFSGPHPAGLVGTHIHFIDPVNAGKTVWTI 240
                         250
                  ....*....|....*..
gi 488978853  241 NYQDAIAIGKLFLDGEL 257
Cdd:pfam05896 241 NYQDVIAIGKLFLTGEL 257
NQRA_SLBB pfam11973
NQRA C-terminal domain; This family consists of the C-terminal domain of several bacterial Na( ...
262-312 5.56e-21

NQRA C-terminal domain; This family consists of the C-terminal domain of several bacterial Na(+)-translocating NADH-quinone reductase subunit A (NQRA) proteins. The Na(+)-translocating NADH: ubiquinone oxidoreductase (Na(+)-NQR) generates an electrochemical Na(+) potential driven by aerobic respiration.


Pssm-ID: 463416 [Multi-domain]  Cd Length: 51  Bit Score: 85.69  E-value: 5.56e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 488978853  262 IIALGGPQVTSPRLVKTTLGASLEDLLAGELQEGENRVISGSVLSGARAHG 312
Cdd:pfam11973   1 VVALAGPQVKKPRYVRTRLGASLSDLTAGELKSGENRVISGSVLTGRKASG 51
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
45-427 8.10e-08

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 54.37  E-value: 8.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  45 VKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAI----HRGERRVLqSVVIDIEGNDAVAfTRYAADALAELPRDTVQQ 120
Cdd:COG4656   49 VKVGDKVLKGQLIAEADGFVSAPVHAPVSGTVVAIepapHPSGLKVL-CIVIEPDGEDEWI-ELEPLADYEDLSPEEIIE 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 121 QLLASGQwtalrtrpfskTPLPGST-PAAIFVNAMDTNPL------AAEPQPIILA------ERAA-FDAGLTVLTRLT- 185
Cdd:COG4656  127 RIREAGI-----------VGLGGAGfPTHVKLSPPPDKKIdtliinGAECEPYLTCddrlmrERAEeIIEGIRILMKALg 195
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 186 -------------------------DGKVHVCQ-----PSGG-------------KLGGHP--LGQVCFNqfsgphpagl 220
Cdd:COG4656  196 akkviigiednkpeaiaalrkalagDDDIEVVVlptkyPQGGekqlikaltgrevPSGGLPadVGVVVQN---------- 265
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 221 PGThihflepvslnkqvwhlnyqdAIAIGKLFLDGELYCERIIALGGPQVTSPRLVKTTLGASLEDLL--AGELQEGENR 298
Cdd:COG4656  266 VGT---------------------AYAIYRAVRDGKPLIERVVTVTGDAVKEPGNLLVRIGTPVSDLLeqAGGFKEEPGK 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853 299 VISGsvlsgarahGPhaFLGR--FHLQVSVVKegrekelfgwvmpgkekfsitrTTLGHFFkrkrfhFSTDTNGGERAMV 376
Cdd:COG4656  325 LIMG---------GP--MMGFalPSLDVPVTK----------------------GTNGILA------LTKEEVPPPEEQP 365
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488978853 377 PI--GNYERVMPLDILPTILLRDLLAGDTDSAQALG---CLEldeedLALCTYVCP 427
Cdd:COG4656  366 CIrcGRCVDACPMGLLPQQLYWYARAGDFDKAEEYNlmdCIE-----CGCCSYVCP 416
RnfC_N pfam13375
RnfC Barrel sandwich hybrid domain; This domain is part of the barrel sandwich hybrid ...
18-96 1.27e-05

RnfC Barrel sandwich hybrid domain; This domain is part of the barrel sandwich hybrid superfamily. It is found at the N-terminus of the RnfC Electron transport complex protein. It appears to be most related to the N-terminal NQRA domain (pfam05896).


Pssm-ID: 433157 [Multi-domain]  Cd Length: 101  Bit Score: 43.70  E-value: 1.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853   18 QQISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIhrGERRV-----LQSVVI 92
Cdd:pfam13375  19 KPIEKLPLPKELVIPLSQHIGAPAEPIVKVGDRVLKGQKIAEADGFVSAPVHASVSGTVKAI--EPRPVphgsgVNCIVI 96

                  ....
gi 488978853   93 DIEG 96
Cdd:pfam13375  97 ENDG 100
AceF COG0508
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component ...
45-83 9.29e-05

Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component [Energy production and conversion]; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440274 [Multi-domain]  Cd Length: 77  Bit Score: 40.44  E-value: 9.29e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 488978853  45 VKEGDRVKKGQILFE---DK---KIPgvcftAPASGIVSAIHRGE 83
Cdd:COG0508   24 VKEGDTVKEGDPLAEvetDKatmEVP-----APAAGVLLEILVKE 63
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
20-98 7.18e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 38.78  E-value: 7.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488978853  20 ISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKIPGVCFTAPASGIVSAIhrgERRVL--------QSVV 91
Cdd:PRK05035  28 IRQAPLPQRLVIPLKQHIGAEGELCVKVGDRVLKGQPLTQGDGRMSLPVHAPTSGTVVAI---EPHPTahpsglaeLCVV 104

                 ....*..
gi 488978853  92 IDIEGND 98
Cdd:PRK05035 105 IEPDGED 111
Biotin_lipoyl pfam00364
Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue ...
28-83 7.51e-03

Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognize the Glycine cleavage system H proteins.


Pssm-ID: 395290 [Multi-domain]  Cd Length: 73  Bit Score: 35.27  E-value: 7.51e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 488978853   28 RVALLGEEYVGMRPAMAVKEGDRVKKGQILFE---DKKIpgVCFTAPASGIVSAIHRGE 83
Cdd:pfam00364   4 KSPMIGESVREGVVEWLVKVGDKVKAGQPLAEveaMKME--MEIPAPVAGVVKEILVPE 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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