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Conserved domains on  [gi|488982648|ref|WP_002893462|]
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MULTISPECIES: ABC transporter permease [Klebsiella]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 28-340 2.64e-103

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 305.84  E-value: 2.64e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  28 VTFSLSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLEL 107
Cdd:COG0601   22 LVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLEL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 108 ATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWAlgpgrlddiyqytvePRSG 187
Cdd:COG0601  102 ALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL---------------PVSG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 188 FalidtwlSGDTAAFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTL 267
Cdd:COG0601  167 R-------VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488982648 268 LTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 28-340 2.64e-103

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 305.84  E-value: 2.64e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  28 VTFSLSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLEL 107
Cdd:COG0601   22 LVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLEL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 108 ATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWAlgpgrlddiyqytvePRSG 187
Cdd:COG0601  102 ALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL---------------PVSG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 188 FalidtwlSGDTAAFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTL 267
Cdd:COG0601  167 R-------VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488982648 268 LTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
28-340 2.62e-64

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 206.97  E-value: 2.62e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  28 VTFSLSALSPVDRVLQIVGDHA-SQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLE 106
Cdd:PRK10914  22 LTFAFVHMIPGDPVMIMAGERGiSPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 107 LATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALfyARLQWALGP--GRLDD-IYQYTVE 183
Cdd:PRK10914 102 LGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIML--VSVHWNLTPvsGRVSDmVFLDDSN 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 184 PRSGFALIDTWLSGDTAAFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNI 263
Cdd:PRK10914 180 PLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNA 259

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488982648 264 RGTLLTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:PRK10914 260 MLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 119-340 4.32e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 105.07  E-value: 4.32e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  119 GIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFyarlqwalgpgrlddiyqytveprsgfalidtwlsgd 198
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------------------- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  199 taaFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSM 278
Cdd:pfam00528  44 ---ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGA 120

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488982648  279 LEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:pfam00528 121 LGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 101-323 4.42e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.09  E-value: 4.42e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 101 FPATLELATLALIVGAVLGIVAGVLCARYAGsPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWalgpgrlddiyqy 180
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 181 tveprsgfalidtwlsgdtaafkNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVL 260
Cdd:cd06261   67 -----------------------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIIL 123

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488982648 261 PNIRGTLLTVTALAWTSMLEGAVLTETVFS----WPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVL 323
Cdd:cd06261  124 PLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 28-340 2.64e-103

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 305.84  E-value: 2.64e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  28 VTFSLSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLEL 107
Cdd:COG0601   22 LVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLEL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 108 ATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWAlgpgrlddiyqytvePRSG 187
Cdd:COG0601  102 ALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL---------------PVSG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 188 FalidtwlSGDTAAFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTL 267
Cdd:COG0601  167 R-------VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488982648 268 LTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
64-340 1.12e-78

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 243.21  E-value: 1.12e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  64 DQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLELATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTL 143
Cdd:COG4168   37 DASLFSGYLFYLQNLLQGDFGISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSL 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 144 LGNSVPIFWLGLLMLALFYARLQWALGPGRLDDIYQytVEPRSGFALIDTWLSGD---TAAFKNAIGHLALPVLVLAYYS 220
Cdd:COG4168  117 LGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYE--IPPVTGFALIDAWLSDSpyrLKAIQSALQHLILPTLVLAVAP 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 221 LASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSMLEGAVLTETVFSWPGIGRYLTT 300
Cdd:COG4168  195 TTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLIN 274

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 488982648 301 ALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:COG4168  275 AIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKR 314
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
28-340 2.62e-64

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 206.97  E-value: 2.62e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  28 VTFSLSALSPVDRVLQIVGDHA-SQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLE 106
Cdd:PRK10914  22 LTFAFVHMIPGDPVMIMAGERGiSPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 107 LATLALIVGAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALfyARLQWALGP--GRLDD-IYQYTVE 183
Cdd:PRK10914 102 LGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIML--VSVHWNLTPvsGRVSDmVFLDDSN 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 184 PRSGFALIDTWLSGDTAAFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNI 263
Cdd:PRK10914 180 PLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNA 259

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488982648 264 RGTLLTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:PRK10914 260 MLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
PRK15110 PRK15110
peptide ABC transporter permease SapB;
67-337 4.09e-53

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 177.57  E-value: 4.09e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  67 LPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLELA----TLALIVGAVLGIVAGVLCARYAgspwDLAVRTFT 142
Cdd:PRK15110  40 LWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCilafGFALLVGIPVGIIAGVTRHKWQ----DNLISALA 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 143 LLGNSVPIFWLGLLMLALFYARLQWALGPGRLDDIYQytVEPRSGFALIDTWLSGD---TAAFKNAIGHLALPVLVLAYY 219
Cdd:PRK15110 116 LLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYE--VKPVTGFALIDAWLSDSpwrDEMIMSAIRHMILPVITLAVA 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 220 SLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSMLEGAVLTETVFSWPGIGRYLT 299
Cdd:PRK15110 194 PTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLI 273

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 488982648 300 TALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDP 337
Cdd:PRK15110 274 NAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 57-340 2.01e-51

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 172.96  E-value: 2.01e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  57 VRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLELATLALIVGAVLGIVAGVLCARYAGSPWDL 136
Cdd:PRK10352  54 TRTMLGLDQPLYVQYGTWLWKALHLDFGISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDF 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 137 AVRTFTLLGNSVPIFWLGLLMLALFYARLQW--ALGPGRLddiyqytveprsgfalidtwlsgdtaafknaiGHLALPVL 214
Cdd:PRK10352 134 AVRFIAFLGVSMPNFWLAFLLVMAFSVYLQWlpAMGYGGW--------------------------------QHIILPAV 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 215 VLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSMLEGAVLTETVFSWPGI 294
Cdd:PRK10352 182 SIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGV 261

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 488982648 295 GRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:PRK10352 262 GRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIR 307
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 35-340 1.67e-41

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 146.78  E-value: 1.67e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  35 LSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLELATLALIV 114
Cdd:PRK15081  29 LLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVSRRPVSEEIASRFMPTLWLTITSMVW 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 115 GAVLGIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWAlgpgrlddiyqytvePRSGfalIDTW 194
Cdd:PRK15081 109 AVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWL---------------PTVG---ADSW 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 195 LsgdtaafknaigHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALA 274
Cdd:PRK15081 171 Q------------HYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQ 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488982648 275 WTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:PRK15081 239 FGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
oppB PRK09471
oligopeptide ABC transporter permease OppB;
62-340 1.87e-34

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 128.26  E-value: 1.87e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  62 GLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAV-FPATLELATLALIVGAVLGIVAGVLCARYAGSPWDLAVRT 140
Cdd:PRK09471  54 HLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASsFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMG 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 141 FTLLGNSVPIFWLGLLMLALFYARLQWALGPGrlddiyqytveprsgfalidtWLSGdtaafknAIGHLALPVLVLAYYS 220
Cdd:PRK09471 134 FAMTGVVIPSFVVAPLLVLIFAITLHWLPGGG---------------------WNGG-------ALKFMILPMVALSLAY 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 221 LASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLpniRGTLLTVTAL---AWTSMLEGAVLTETVFSWPGIGRY 297
Cdd:PRK09471 186 IASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHAL---KPALLPVLSYmgpAFVGIITGSMVIETIFGLPGIGQL 262

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 488982648 298 LTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:PRK09471 263 FVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 119-340 4.32e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 105.07  E-value: 4.32e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  119 GIVAGVLCARYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFyarlqwalgpgrlddiyqytveprsgfalidtwlsgd 198
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------------------- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  199 taaFKNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSM 278
Cdd:pfam00528  44 ---ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGA 120

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488982648  279 LEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRLTDPRVR 340
Cdd:pfam00528 121 LGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 56-339 2.19e-21

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 93.66  E-value: 2.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648  56 QVRHQLGLDQPLPVQFWHYLVNLAHGDLGIASATGQPVLHDLLAVFPATLELATLALIVGAVLGIVAGVLCARYAGSPWD 135
Cdd:PRK15133  88 EITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFD 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 136 LAVRTFTLLGNSVPIFWLGLLMLALFYARLQWALGPGRLDDIYQYTVEPrsgfalidtWLSGDTaafkNAIGHLALPVLV 215
Cdd:PRK15133 168 VWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLP---------WYQKIT----DYLWHITLPVLA 234

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 216 LAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNirGTLLTVTALAWT--SM-LEGAVLTETVFSWP 292
Cdd:PRK15133 235 TVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRN--AMLLVIAGFPATfiSMfFTGSLLIEVMFSLN 312

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488982648 293 GIGRYLTTALFAGDtTAIMGGTL----LIGvsfVLINNLTDLLVRLTDPRV 339
Cdd:PRK15133 313 GLGLLGYEATVSRD-YPVMFGTLyiftLIG---LLLNIVSDISYTLVDPRI 359
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 101-323 4.42e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.09  E-value: 4.42e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 101 FPATLELATLALIVGAVLGIVAGVLCARYAGsPWDLAVRTFTLLGNSVPIFWLGLLMLALFYARLQWalgpgrlddiyqy 180
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 181 tveprsgfalidtwlsgdtaafkNAIGHLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVL 260
Cdd:cd06261   67 -----------------------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIIL 123

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488982648 261 PNIRGTLLTVTALAWTSMLEGAVLTETVFS----WPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVL 323
Cdd:cd06261  124 PLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 28-108 1.80e-12

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 63.01  E-value: 1.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648   28 VTFSLSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLPVQFWHYLVNLAHGD------------LGIASATGQPVLH 95
Cdd:pfam19300  22 VTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdfgavghcpapcLGYSFANNEPVWD 101

                          90
                  ....*....|...
gi 488982648   96 DLLAVFPATLELA 108
Cdd:pfam19300 102 TIMDRFPTTLSLA 114
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 108-295 5.48e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 65.13  E-value: 5.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 108 ATLALIVGAVLGIVAGvlcarYAGSPWDLAVRTFTLLGNSVPIFWLGLLMLALFyarlqwalGPGrlddiyqytveprsg 187
Cdd:COG1173   89 VLIALVIGVLLGLLAG-----YFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVL--------GPG--------------- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 188 falidtwlsgdtaafknaighLALPVLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTL 267
Cdd:COG1173  141 ---------------------LLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPL 199

                        170       180
                 ....*....|....*....|....*...
gi 488982648 268 LTVTALawtsMLEGAVLTETVFSWPGIG 295
Cdd:COG1173  200 IVQATL----GIASAILAEAGLSFLGLG 223
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 103-334 1.35e-05

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 45.91  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 103 ATLELATLALIVGAVLGIVAGVLCARYAgsPWDLAVRTFTLLGNSVPIF-WLGLLMLalfyarlqwalgpgrlddiyqyt 181
Cdd:COG0600   65 ASLLRVLLGFALAALLGVPLGLLLGLSR--LLRRLLDPLLVFLRPIPPLaLAPLLIL----------------------- 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 182 veprsgfalidtWLSGDTAAfknaighlalPVLVLAYYSLASITRLTRSAcLSEMNKEYILLARAKGAGEMTILLRHVLP 261
Cdd:COG0600  120 ------------WFGIGEAS----------KIFVIFLGAFFPILLNTAAG-VRSVDPELLELARSLGASRWQILRKVVLP 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488982648 262 NIRGTLLTVTALAWTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVSFVLINNLTDLLVRL 334
Cdd:COG0600  177 AALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERR 249
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
214-277 3.50e-04

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 41.69  E-value: 3.50e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488982648 214 LVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTS 277
Cdd:PRK10913 166 LALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSN 229
nikC PRK10417
nickel transporter permease NikC; Provisional
 213-273 3.73e-04

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 41.58  E-value: 3.73e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488982648 213 VLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTAL 273
Cdd:PRK10417 133 IIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATL 193
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
224-274 4.45e-04

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 41.34  E-value: 4.45e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488982648 224 ITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALA 274
Cdd:COG4171  173 FIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRA 223
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 213-273 5.51e-04

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 41.29  E-value: 5.51e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488982648 213 VLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPN------------IRGTLLTVTAL 273
Cdd:COG4239  207 LGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNamvatltflpfiLSGAITTLTSL 279
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 213-261 2.49e-03

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 39.33  E-value: 2.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 488982648 213 VLVLAYYSLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLP 261
Cdd:PRK15082 166 IIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILP 214
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 220-295 5.82e-03

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 37.89  E-value: 5.82e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488982648 220 SLASITRLTRSACLSEMNKEYILLARAKGAGEMTILLRHVLPNIRGTLLTVTALAWTSMlegaVLTETVFSWPGIG 295
Cdd:PRK15406 175 SWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSM----ILFESFLSFLGLG 246
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 104-275 8.93e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 37.42  E-value: 8.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 104 TLELATLALIVGAVLGIVAGVLCARYAGsPWDLAVRTFTLLGNSVPIFWLGLlMLALFYARLQWaLGpGRLDDIyqytve 183
Cdd:COG0555   59 SLGTALIAALINLVFGLPLAWVLVRYRF-PGKRLVDALVDLPFALPTAVAGI-ALLLLFGPNGW-LG-QLLAPL------ 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488982648 184 prsGFALIDTWLsgdtaafknAIghlalpVLVLAYYSLASITRLTRSAcLSEMNKEYILLARAKGAGEMTILLRHVLPNI 263
Cdd:COG0555  129 ---GIKVAFTPL---------GI------VLAQTFVSLPFVVRTVQPV-LEELDPELEEAAATLGASRWQTFRRVILPLL 189

                        170
                 ....*....|..
gi 488982648 264 RGTLLTVTALAW 275
Cdd:COG0555  190 LPALLTGFALAF 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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