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Conserved domains on  [gi|488994101|ref|WP_002904827|]
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MULTISPECIES: sulfite exporter TauE/SafE family protein [Klebsiella]

Protein Classification

sulfite exporter TauE/SafE family protein( domain architecture ID 10487553)

sulfite exporter TauE/SafE family protein is an inner membrane anion permease involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate

Gene Ontology:  GO:0006810|GO:0016020
PubMed:  22192777
TCDB:  2.A.102

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
10-226 4.62e-13

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


:

Pssm-ID: 460386  Cd Length: 235  Bit Score: 66.45  E-value: 4.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   10 LLIFIAAGLVKGVTGMGLPTVAMGLLGLLMPPQAAAALLVLPSLLTNLWQLLAGPALAQI-VRRLWLMMTGIIIGTLAGS 88
Cdd:pfam01925   1 LLAGLLAGFVGGLLGFGGGLIAVPLLLLLLPPAVAVGTSLLAAVATSLSGALAHRRRGAVdWRLLLRLLLGGLIGALLGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   89 SLLIGLNPRWSALALGAALIVYAGYALCSPVFQVSGRVEKWLSP---------LMGGLTGVITGATGVFVIPAVPWLQAL 159
Cdd:pfam01925  81 LLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGAAPRARRRRPGplalallggLIGFLSGLFGIGGGFLLVPALLYLLGL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488994101  160 GFRRdeLVQALGLSFTLSTLALAAGLALHDGWHddaWLLSALALLPALLGMWLGQRIRSRLSPQRFR 226
Cdd:pfam01925 161 PLKK--AVGTSLLLFLVSNLAALLGYALLGAVD---WPLLLLLLLGALLGAYLGARLARRLPPRLLR 222
 
Name Accession Description Interval E-value
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
10-226 4.62e-13

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 66.45  E-value: 4.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   10 LLIFIAAGLVKGVTGMGLPTVAMGLLGLLMPPQAAAALLVLPSLLTNLWQLLAGPALAQI-VRRLWLMMTGIIIGTLAGS 88
Cdd:pfam01925   1 LLAGLLAGFVGGLLGFGGGLIAVPLLLLLLPPAVAVGTSLLAAVATSLSGALAHRRRGAVdWRLLLRLLLGGLIGALLGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   89 SLLIGLNPRWSALALGAALIVYAGYALCSPVFQVSGRVEKWLSP---------LMGGLTGVITGATGVFVIPAVPWLQAL 159
Cdd:pfam01925  81 LLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGAAPRARRRRPGplalallggLIGFLSGLFGIGGGFLLVPALLYLLGL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488994101  160 GFRRdeLVQALGLSFTLSTLALAAGLALHDGWHddaWLLSALALLPALLGMWLGQRIRSRLSPQRFR 226
Cdd:pfam01925 161 PLKK--AVGTSLLLFLVSNLAALLGYALLGAVD---WPLLLLLLLGALLGAYLGARLARRLPPRLLR 222
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
7-246 4.72e-08

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 52.12  E-value: 4.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   7 ISFLLIFIAAGLVKGVTGMGLPTVAMGLLGLL-MPPQAAAALLVLPSLLTNLWQLLAGPALAQI-VRRLWLMMTGIIIGT 84
Cdd:COG0730    5 LLLLLAGFLAGFLDGLLGVGGGLITVPALLLFgLPPAVAVGTSLLAVVFTSLSGALAHRRRGNVdWRLLLPLALGALIGA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101  85 LAGSSLLIGLNPRWSALALGAALIVYAGYALCSPVFQVS-----GRVEKWLSPLMGGLTGVITGATGVFVIPAVPWLQAL 159
Cdd:COG0730   85 LLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEperrlPRRSPLLLLLLGFVIGFLSGLFGIGGGFLLVPALVL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101 160 GFRRDeLVQALGLSFTLSTLALAAGLALHDGWHDDAWLLSALALLPALLGMWLGQRIRSRLSPQRFRQGFLLFLLALGIE 239
Cdd:COG0730  165 LLGLP-LKRAVATSLALIFVTALAGLIGFALLGYVDWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLVGLK 243

                 ....*..
gi 488994101 240 LIARGWL 246
Cdd:COG0730  244 LLLKALG 250
 
Name Accession Description Interval E-value
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
10-226 4.62e-13

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 66.45  E-value: 4.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   10 LLIFIAAGLVKGVTGMGLPTVAMGLLGLLMPPQAAAALLVLPSLLTNLWQLLAGPALAQI-VRRLWLMMTGIIIGTLAGS 88
Cdd:pfam01925   1 LLAGLLAGFVGGLLGFGGGLIAVPLLLLLLPPAVAVGTSLLAAVATSLSGALAHRRRGAVdWRLLLRLLLGGLIGALLGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   89 SLLIGLNPRWSALALGAALIVYAGYALCSPVFQVSGRVEKWLSP---------LMGGLTGVITGATGVFVIPAVPWLQAL 159
Cdd:pfam01925  81 LLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGAAPRARRRRPGplalallggLIGFLSGLFGIGGGFLLVPALLYLLGL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488994101  160 GFRRdeLVQALGLSFTLSTLALAAGLALHDGWHddaWLLSALALLPALLGMWLGQRIRSRLSPQRFR 226
Cdd:pfam01925 161 PLKK--AVGTSLLLFLVSNLAALLGYALLGAVD---WPLLLLLLLGALLGAYLGARLARRLPPRLLR 222
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
7-246 4.72e-08

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 52.12  E-value: 4.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101   7 ISFLLIFIAAGLVKGVTGMGLPTVAMGLLGLL-MPPQAAAALLVLPSLLTNLWQLLAGPALAQI-VRRLWLMMTGIIIGT 84
Cdd:COG0730    5 LLLLLAGFLAGFLDGLLGVGGGLITVPALLLFgLPPAVAVGTSLLAVVFTSLSGALAHRRRGNVdWRLLLPLALGALIGA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101  85 LAGSSLLIGLNPRWSALALGAALIVYAGYALCSPVFQVS-----GRVEKWLSPLMGGLTGVITGATGVFVIPAVPWLQAL 159
Cdd:COG0730   85 LLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEperrlPRRSPLLLLLLGFVIGFLSGLFGIGGGFLLVPALVL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488994101 160 GFRRDeLVQALGLSFTLSTLALAAGLALHDGWHDDAWLLSALALLPALLGMWLGQRIRSRLSPQRFRQGFLLFLLALGIE 239
Cdd:COG0730  165 LLGLP-LKRAVATSLALIFVTALAGLIGFALLGYVDWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLVGLK 243

                 ....*..
gi 488994101 240 LIARGWL 246
Cdd:COG0730  244 LLLKALG 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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