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Conserved domains on  [gi|488996073|ref|WP_002906780|]
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MULTISPECIES: YncE family protein [Klebsiella]

Protein Classification

YncE family protein( domain architecture ID 11465355)

YncE family protein contains repeats resembling the NHL (NCL-1, HT2A and LIN-41) and YVTN-type repeats, similar to DNA-binding beta-propeller protein YncE and Bacillus subtilis uncharacterized protein YwhL

CATH:  2.130.10.10
PubMed:  22120742|10607670
SCOP:  4002745

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
155-331 1.91e-20

DNA-binding beta-propeller fold protein YncE [General function prediction only];


:

Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 88.98  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 155 VYITGLGKESVIWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNA-DGELLTIDSESNTIASRKKLQDDGKahfy 233
Cdd:COG3391   38 AAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSgSGRVSVIDLATGKVVATIPVGGGPR---- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 234 lNLSLDTAGHRAFITDSKQPEVLVVDTRDGKVLEKIAAPESL-AVLFNPARNEAYVTHRKAGE----VSVIDGKSYKVVK 308
Cdd:COG3391  114 -GLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPDGKRLYVANSGSNTvsviVSVIDTATGKVVA 192

                        170       180
                 ....*....|....*....|...
gi 488996073 309 TFKTPTHPNSLALSEDGKTLYVS 331
Cdd:COG3391  193 TIPVGGGPVGVAVSPDGRRLYVA 215
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
38-219 3.16e-16

DNA-binding beta-propeller fold protein YncE [General function prediction only];


:

Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 77.04  E-value: 3.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  38 AVGKGAYEMAYSQQENALWVATSQSrsldkgGVVYRLDPTTLDVTQIIHNDLKPFGATINHATGTLWFGNTVDSTVTAID 117
Cdd:COG3391   65 AAVADADGADAGADGRRLYVANSGS------GRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVID 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 118 AKTGAVKGRLVLDErqrsetvrplQPRELAVNEQTNTVYITGLGKESV---IWVVDGATLKLKTTITgTGAMATGLAIDP 194
Cdd:COG3391  139 TATGKVVATIPVGA----------GPHGIAVDPDGKRLYVANSGSNTVsviVSVIDTATGKVVATIP-VGGGPVGVAVSP 207

                        170       180
                 ....*....|....*....|....*
gi 488996073 195 QAKRLYTTNADGEllTIDSESNTIA 219
Cdd:COG3391  208 DGRRLYVANRGSN--TSNGGSNTVS 230
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
155-331 1.91e-20

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 88.98  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 155 VYITGLGKESVIWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNA-DGELLTIDSESNTIASRKKLQDDGKahfy 233
Cdd:COG3391   38 AAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSgSGRVSVIDLATGKVVATIPVGGGPR---- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 234 lNLSLDTAGHRAFITDSKQPEVLVVDTRDGKVLEKIAAPESL-AVLFNPARNEAYVTHRKAGE----VSVIDGKSYKVVK 308
Cdd:COG3391  114 -GLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPDGKRLYVANSGSNTvsviVSVIDTATGKVVA 192

                        170       180
                 ....*....|....*....|...
gi 488996073 309 TFKTPTHPNSLALSEDGKTLYVS 331
Cdd:COG3391  193 TIPVGGGPVGVAVSPDGRRLYVA 215
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
38-219 3.16e-16

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 77.04  E-value: 3.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  38 AVGKGAYEMAYSQQENALWVATSQSrsldkgGVVYRLDPTTLDVTQIIHNDLKPFGATINHATGTLWFGNTVDSTVTAID 117
Cdd:COG3391   65 AAVADADGADAGADGRRLYVANSGS------GRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVID 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 118 AKTGAVKGRLVLDErqrsetvrplQPRELAVNEQTNTVYITGLGKESV---IWVVDGATLKLKTTITgTGAMATGLAIDP 194
Cdd:COG3391  139 TATGKVVATIPVGA----------GPHGIAVDPDGKRLYVANSGSNTVsviVSVIDTATGKVVATIP-VGGGPVGVAVSP 207

                        170       180
                 ....*....|....*....|....*
gi 488996073 195 QAKRLYTTNADGEllTIDSESNTIA 219
Cdd:COG3391  208 DGRRLYVANRGSN--TSNGGSNTVS 230
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 92-330 4.58e-11

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 63.14  E-value: 4.58e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073   92 FGATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERqrsetvrplqPRELAVNEQTNTVYITGlGKESVIWVVDG 171
Cdd:TIGR03866   2 LLAAGSAAAETAYVSNEKDNTISVIDTATLKVTRTFPVGQR----------PRGITFSKDGKLLYVCA-SDSDTIQVIDP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  172 ATLKLKTTITgTGAMATGLAIDPQAKRLYTTNADGELLT-IDsesntIASRKKLQD--------------DGK------- 229
Cdd:TIGR03866  71 ATGEVLHTLP-SGPDPEQFALHPNGKILYIANEDDALVTvID-----IETRKVLAQidvgvepegmavspDGKivvntse 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  230 ----AHFylnlsLDTAGHRafITDSkqpevLVVDTRdgkvlekiaaPESLAvlFNPARNEAYVTHRKAGEVSVIDGKSYK 305
Cdd:TIGR03866 145 ttnmAHW-----IDTATYE--IVDN-----TLVDAR----------PRFAE--FTADGKELWVSSEIGGTVTVIDVATRK 200

                         250       260       270
                  ....*....|....*....|....*....|...
gi 488996073  306 VVK--TFKTP-THPNSL-----ALSEDGKTLYV 330
Cdd:TIGR03866 201 VIKkiTFAIPgVHPEKVqpvgiKLTKDGKTAFV 233
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 83-225 5.93e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 47.34  E-value: 5.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073   83 QIIHN---DLKPFGATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERqrseTVRP--LQPRELAVNEQTNTVYI 157
Cdd:TIGR03866 158 EIVDNtlvDARPRFAEFTADGKELWVSSEIGGTVTVIDVATRKVIKKITFAIP----GVHPekVQPVGIKLTKDGKTAFV 233

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488996073  158 tGLGKESVIWVVDGATLKLKTTITgTGAMATGLAIDPQAKRLYTTNA-DGELLTIDsesntIASRKKLQ 225
Cdd:TIGR03866 234 -ALGPANRVAVVDAKTYEVLDYLL-VGQRVWQLAFTPDESRLLTTNGvSNDVSVID-----VAALKVIK 295
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 139-336 1.08e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 46.95  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 139 RPLQPRELAVNEQTNTVYITGLGKESViWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDSESNTI 218
Cdd:cd20718   14 RELPPVAYGIWDLENLMVVVERDAGSV-LVIDGSTHEVLGRIDDGGAQVHVVVFSPDGRFAYVISRDGWLTKIDLYTLRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 219 ASRKK---------LQDDGKahfYLNLSLDTAGHrAFITDSKQPEVL-VVDTRDGKVLEKIAAPESlAVLFNPARNEAYV 288
Cdd:cd20718   93 VASIRigvnsrgiaLSDDGK---YVIAGNYEPGH-VVILDADTLEPLkVIPTTGVNDDGIIESRVG-AILETPPGPYFLV 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488996073 289 THRKAGEVSVID---GKSYKVVKTFKTPTHPNSLALSEDGKTLYVSVkQAS 336
Cdd:cd20718  168 ALKDAGSVWVIDysdPDGNKVTDIGNIGRPLHDAFLDPDGRYFIVAS-QGS 217
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 142-337 5.35e-03

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 38.36  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  142 QPRELAVNEQTNTVY-ITGLGKESVIWVV----DGATLKLKTTITGTGAMATGLAIDPQAKRLYTTN------------A 204
Cdd:pfam10282  38 NPSYLALSPDGRTLYaVNEEGDQGGVAAFridpDSGALTLLNQVPTGGASPCHLSVDPDGRFLFVANyhggsvsvfpldA 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  205 DGELLTIDSESNTIAS--RKKLQDDGKAHFylnLSLDTAGHRAFITDSKQPEVLV--VDTRDGKvLEKIAA--------P 272
Cdd:pfam10282 118 DGSLGELSQVVQHEGSgpPPERQESPHPHS---VDLTPDGKFLVVPDLGTDRVRVykLDAGGGK-LTPPASvqtppgsgP 193

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488996073  273 ESLAvlFNPARNEAYVTHRKAGEVSV--IDGKSYKVVKTFKTPTHP------NSLA---LSEDGKTLYVSVKQASS 337
Cdd:pfam10282 194 RHLA--FHPNGKYAYVVNELSSTVTVfeYDPATGTFEELQTVSTLPegftgtNGAAairVSPDGKFLYVSNRGHDS 267
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
155-331 1.91e-20

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 88.98  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 155 VYITGLGKESVIWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNA-DGELLTIDSESNTIASRKKLQDDGKahfy 233
Cdd:COG3391   38 AAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSgSGRVSVIDLATGKVVATIPVGGGPR---- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 234 lNLSLDTAGHRAFITDSKQPEVLVVDTRDGKVLEKIAAPESL-AVLFNPARNEAYVTHRKAGE----VSVIDGKSYKVVK 308
Cdd:COG3391  114 -GLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPDGKRLYVANSGSNTvsviVSVIDTATGKVVA 192

                        170       180
                 ....*....|....*....|...
gi 488996073 309 TFKTPTHPNSLALSEDGKTLYVS 331
Cdd:COG3391  193 TIPVGGGPVGVAVSPDGRRLYVA 215
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
62-303 5.78e-20

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 87.44  E-value: 5.78e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  62 SRSLDKGGVVYRLDPTTLDVTQIIHNDLKPFGATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERqrsetvrpl 141
Cdd:COG3391   41 SGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLATGKVVATIPVGGG--------- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 142 qPRELAVNEQTNTVYITGLGkESVIWVVDGATLKLKTTITgTGAMATGLAIDPQAKRLYTTNADgelltidseSNTIasr 221
Cdd:COG3391  112 -PRGLAVDPDGGRLYVADSG-NGRVSVIDTATGKVVATIP-VGAGPHGIAVDPDGKRLYVANSG---------SNTV--- 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 222 kklqddgkahfylnlsldtaghrAFItdskqpeVLVVDTRDGKVLEKIAAPES-LAVLFNPARNEAYVTHR-------KA 293
Cdd:COG3391  177 -----------------------SVI-------VSVIDTATGKVVATIPVGGGpVGVAVSPDGRRLYVANRgsntsngGS 226

                        250
                 ....*....|
gi 488996073 294 GEVSVIDGKS 303
Cdd:COG3391  227 NTVSVIDLAT 236
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
38-219 3.16e-16

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 77.04  E-value: 3.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  38 AVGKGAYEMAYSQQENALWVATSQSrsldkgGVVYRLDPTTLDVTQIIHNDLKPFGATINHATGTLWFGNTVDSTVTAID 117
Cdd:COG3391   65 AAVADADGADAGADGRRLYVANSGS------GRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVID 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 118 AKTGAVKGRLVLDErqrsetvrplQPRELAVNEQTNTVYITGLGKESV---IWVVDGATLKLKTTITgTGAMATGLAIDP 194
Cdd:COG3391  139 TATGKVVATIPVGA----------GPHGIAVDPDGKRLYVANSGSNTVsviVSVIDTATGKVVATIP-VGGGPVGVAVSP 207

                        170       180
                 ....*....|....*....|....*
gi 488996073 195 QAKRLYTTNADGEllTIDSESNTIA 219
Cdd:COG3391  208 DGRRLYVANRGSN--TSNGGSNTVS 230
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
54-277 2.79e-12

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 66.20  E-value: 2.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  54 ALWVAtsqsrsLDKGGVVYRLDPTTLDVTQIIHNDL-KPFGATINHAtGTLWFGNTVDSTVTAIDAKTGAVKgRLVLDER 132
Cdd:COG4257   29 AVWFT------DQGGGRIGRLDPATGEFTEYPLGGGsGPHGIAVDPD-GNLWFTDNGNNRIGRIDPKTGEIT-TFALPGG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 133 QRsetvrplQPRELAVNEQTNtVYITGLGKeSVIWVVDGATLKLKT-TITGTGAMATGLAIDPQAKRLYTTNADGELLTI 211
Cdd:COG4257  101 GS-------NPHGIAFDPDGN-LWFTDQGG-NRIGRLDPATGEVTEfPLPTGGAGPYGIAVDPDGNLWVTDFGANAIGRI 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488996073 212 DSESNTIaSRKKLQDDGKAHFYlnLSLDTAGhRAFITDSKQPEVLVVDTRDGKVLE-----KIAAPESLAV 277
Cdd:COG4257  172 DPDTGTL-TEYALPTPGAGPRG--LAVDPDG-NLWVADTGSGRIGRFDPKTGTVTEyplpgGGARPYGVAV 238
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 92-330 4.58e-11

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 63.14  E-value: 4.58e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073   92 FGATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERqrsetvrplqPRELAVNEQTNTVYITGlGKESVIWVVDG 171
Cdd:TIGR03866   2 LLAAGSAAAETAYVSNEKDNTISVIDTATLKVTRTFPVGQR----------PRGITFSKDGKLLYVCA-SDSDTIQVIDP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  172 ATLKLKTTITgTGAMATGLAIDPQAKRLYTTNADGELLT-IDsesntIASRKKLQD--------------DGK------- 229
Cdd:TIGR03866  71 ATGEVLHTLP-SGPDPEQFALHPNGKILYIANEDDALVTvID-----IETRKVLAQidvgvepegmavspDGKivvntse 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  230 ----AHFylnlsLDTAGHRafITDSkqpevLVVDTRdgkvlekiaaPESLAvlFNPARNEAYVTHRKAGEVSVIDGKSYK 305
Cdd:TIGR03866 145 ttnmAHW-----IDTATYE--IVDN-----TLVDAR----------PRFAE--FTADGKELWVSSEIGGTVTVIDVATRK 200

                         250       260       270
                  ....*....|....*....|....*....|...
gi 488996073  306 VVK--TFKTP-THPNSL-----ALSEDGKTLYV 330
Cdd:TIGR03866 201 VIKkiTFAIPgVHPEKVqpvgiKLTKDGKTAFV 233
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 67-289 1.26e-08

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 55.28  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  67 KGGVVYRLDPTTLDVTQIIHNDLKPFGATInHATGTLWFGNTvDSTVTAIDAKTGAVkgRLVLDERQRSETvrplQPREL 146
Cdd:COG3386   27 PGGRIHRYDPDGGAVEVFAEPSGRPNGLAF-DPDGRLLVADH-GRGLVRFDPADGEV--TVLADEYGKPLN----RPNDG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 147 AVNEQtNTVYITGLGKES---VIWVVDgATLKLKTTITGTgAMATGLAIDPQAKRLYTTN-ADGELLTID-SESNTIASR 221
Cdd:COG3386   99 VVDPD-GRLYFTDMGEYLptgALYRVD-PDGSLRVLADGL-TFPNGIAFSPDGRTLYVADtGAGRIYRFDlDADGTLGNR 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488996073 222 KKLQDDGKAHFYL-NLSLDTAGHrAFITDSKQPEVLVVDtRDGKVLEKIAAPESL--AVLFN-PARNEAYVT 289
Cdd:COG3386  176 RVFADLPDGPGGPdGLAVDADGN-LWVALWGGGGVVRFD-PDGELLGRIELPERRptNVAFGgPDLRTLYVT 245
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
91-331 1.77e-07

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 51.94  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  91 PFGATINhATGTLWFGNTVDSTVTAIDAKTGAVKgrlvlderqRSETVRPLQPRELAVNEQtNTVYITGLGkESVIWVVD 170
Cdd:COG4257   19 PRDVAVD-PDGAVWFTDQGGGRIGRLDPATGEFT---------EYPLGGGSGPHGIAVDPD-GNLWFTDNG-NNRIGRID 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 171 GATLKLKTTITGTGAMA-TGLAIDPQAkRLYTTNADGELLT-IDSESNTIASRKKLQDDGKAHfylNLSLDTAGhRAFIT 248
Cdd:COG4257   87 PKTGEITTFALPGGGSNpHGIAFDPDG-NLWFTDQGGNRIGrLDPATGEVTEFPLPTGGAGPY---GIAVDPDG-NLWVT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 249 DSKQPEVLVVDTRDGKVLE-----KIAAPESLAVLfnpARNEAYVTHRKAGEVSVIDGKSyKVVKTFKTPT---HPNSLA 320
Cdd:COG4257  162 DFGANAIGRIDPDTGTLTEyalptPGAGPRGLAVD---PDGNLWVADTGSGRIGRFDPKT-GTVTEYPLPGggaRPYGVA 237

                        250
                 ....*....|.
gi 488996073 321 LSEDGKtLYVS 331
Cdd:COG4257  238 VDGDGR-VWFA 247
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
95-331 2.91e-07

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 51.45  E-value: 2.91e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  95 TINHATGTLWFGNTVDST-----VTAIDAKTGAvkgrlvLDERQRSETVRplQPRELAVNEQTNTVYITGLGKESVIWV- 168
Cdd:COG2706    2 KRLLLSTFVYVGTYTSGEsegiyVFRLDTATGE------LTLLGLVAALG--NPSFLALSPDGRFLYAVNEVDDGGVSAf 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 169 -VDGAT--LKLKTTITGTGAMATGLAIDPQAKRLYTTN------------ADGELLTI-----DSESNTIASRkklQDDG 228
Cdd:COG2706   74 rIDPADgtLTLLNTVSSGGASPCHLSVDPDGRFLFVANygggsvsvfpidADGSLGEPvqviqHEGSGPNPER---QEGP 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 229 KAHFylnLSLDTAGHRAFITDSKQPEVLV--VDTRDGK-------VLEKIAAPESLAvlFNPARNEAYVTHRKAGEVSV- 298
Cdd:COG2706  151 HAHS---VVFDPDGRFLYVPDLGTDRIYVyrLDPATGKlpeppevSLPPGSGPRHLA--FHPNGRFAYVINELDSTVSVy 225

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 488996073 299 -IDGKSYKVVKTFKTPTHPNS---------LALSEDGKTLYVS 331
Cdd:COG2706  226 aYDAATGTLTLIQTVSTLPEDftgenwaadIHISPDGRFLYVS 268
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 146-331 6.63e-07

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 50.42  E-value: 6.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  146 LAVNEQTNTVYITgLGKESVIWVVDGATLKLKTTITgTGAMATGLAIDPQAKRLYTTNADGELL-TIDSESNTIasRKKL 224
Cdd:TIGR03866   4 AAGSAAAETAYVS-NEKDNTISVIDTATLKVTRTFP-VGQRPRGITFSKDGKLLYVCASDSDTIqVIDPATGEV--LHTL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  225 QDDGKAHFYlnlSLDTAGHRAFITDSKQPEVLVVDTRDGKVLEKI---AAPESLAVlfNPARNEAYVTHRKAGEVSVIDG 301
Cdd:TIGR03866  80 PSGPDPEQF---ALHPNGKILYIANEDDALVTVIDIETRKVLAQIdvgVEPEGMAV--SPDGKIVVNTSETTNMAHWIDT 154

                         170       180       190
                  ....*....|....*....|....*....|
gi 488996073  302 KSYKVVKTFKTPTHPNSLALSEDGKTLYVS 331
Cdd:TIGR03866 155 ATYEIVDNTLVDARPRFAEFTADGKELWVS 184
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 83-225 5.93e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 47.34  E-value: 5.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073   83 QIIHN---DLKPFGATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERqrseTVRP--LQPRELAVNEQTNTVYI 157
Cdd:TIGR03866 158 EIVDNtlvDARPRFAEFTADGKELWVSSEIGGTVTVIDVATRKVIKKITFAIP----GVHPekVQPVGIKLTKDGKTAFV 233

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488996073  158 tGLGKESVIWVVDGATLKLKTTITgTGAMATGLAIDPQAKRLYTTNA-DGELLTIDsesntIASRKKLQ 225
Cdd:TIGR03866 234 -ALGPANRVAVVDAKTYEVLDYLL-VGQRVWQLAFTPDESRLLTTNGvSNDVSVID-----VAALKVIK 295
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 139-336 1.08e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 46.95  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 139 RPLQPRELAVNEQTNTVYITGLGKESViWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDSESNTI 218
Cdd:cd20718   14 RELPPVAYGIWDLENLMVVVERDAGSV-LVIDGSTHEVLGRIDDGGAQVHVVVFSPDGRFAYVISRDGWLTKIDLYTLRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 219 ASRKK---------LQDDGKahfYLNLSLDTAGHrAFITDSKQPEVL-VVDTRDGKVLEKIAAPESlAVLFNPARNEAYV 288
Cdd:cd20718   93 VASIRigvnsrgiaLSDDGK---YVIAGNYEPGH-VVILDADTLEPLkVIPTTGVNDDGIIESRVG-AILETPPGPYFLV 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488996073 289 THRKAGEVSVID---GKSYKVVKTFKTPTHPNSLALSEDGKTLYVSVkQAS 336
Cdd:cd20718  168 ALKDAGSVWVIDysdPDGNKVTDIGNIGRPLHDAFLDPDGRYFIVAS-QGS 217
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
142-331 2.31e-05

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 45.40  E-value: 2.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 142 QPRELAVNEQtNTVYITGLGKeSVIWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDSESNTIaSR 221
Cdd:COG4257   18 GPRDVAVDPD-GAVWFTDQGG-GRIGRLDPATGEFTEYPLGGGSGPHGIAVDPDGNLWFTDNGNNRIGRIDPKTGEI-TT 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 222 KKLQDDGKAHFYlnLSLDTAGhRAFITDSKQPEVLVVDTRDGKVLE-----KIAAPESLAVlfnPARNEAYVTHRKAGEV 296
Cdd:COG4257   95 FALPGGGSNPHG--IAFDPDG-NLWFTDQGGNRIGRLDPATGEVTEfplptGGAGPYGIAV---DPDGNLWVTDFGANAI 168

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 488996073 297 SVIDGKSyKVVKTFKTPT---HPNSLALSEDGkTLYVS 331
Cdd:COG4257  169 GRIDPDT-GTLTEYALPTpgaGPRGLAVDPDG-NLWVA 204
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
40-124 5.88e-05

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 44.24  E-value: 5.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  40 GKGAYEMAYSQQeNALWVATSQsrsldkGGVVYRLDPTTLDVTQI-IHNDLK-PFGATINHAtGTLWFGNTVDSTVTAID 117
Cdd:COG4257  144 GAGPYGIAVDPD-GNLWVTDFG------ANAIGRIDPDTGTLTEYaLPTPGAgPRGLAVDPD-GNLWVADTGSGRIGRFD 215


                 ....*..
gi 488996073 118 AKTGAVK 124
Cdd:COG4257  216 PKTGTVT 222
NHL_like_6 cd14962
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 234-330 1.42e-04

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271332 [Multi-domain]  Cd Length: 271  Bit Score: 42.96  E-value: 1.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 234 LNLSLDTAGhRAFITDSKQPEVLVVDtRDGKVLEKIAA------PESLAVlfNPARNEAYVTHRKAGEVSVIDGKSyKVV 307
Cdd:cd14962   60 IGVAIDANG-NLYVSDAELGKVFVFD-RDGKFLRAIGAgalfkrPTGIAV--DPAGKRLYVVDTLAHKVKVFDLDG-RLL 134

                         90       100       110
                 ....*....|....*....|....*....|
gi 488996073 308 KTFKTP-------THPNSLALSEDGKtLYV 330
Cdd:cd14962  135 FDIGKRgsgpgefNLPTDLAVDRDGN-LYV 163
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 156-314 2.32e-04

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 42.71  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 156 YITGLGKESVIWVVDGATLKLKTTITgTGAM---ATGlAIDPQAKRLYTTNADGELLT-IDSESNTIAsrKKLQDDGKAH 231
Cdd:cd20718  210 FIVASQGSNTMWVLDLKTGKVVARIP-TGKTphpGPG-ATWGRKGVTATPHLGEGIVTvWDLDTWKPV--KYIPTPGPGR 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 232 FYLN------LSLDTAGHrafitDSKQPEVLVVDTRDGKVLEKIA---APESLAVLFNPARNEAYVTHRKAGEVSVIDGK 302
Cdd:cd20718  286 FVRThpsspyVWADTVFG-----PENADEIYVIDKETLKVVKTLIpkpGKRALHPEFTRDGKYVYVSVWDGGEVVVYDAE 360

                        170
                 ....*....|....
gi 488996073 303 SYKVVKTFK--TPT 314
Cdd:cd20718  361 TLELVKRIPaeTPT 374
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 168-318 2.53e-04

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 42.71  E-value: 2.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 168 VVDGATLKLKTTITGTGA---------MATGLAIDPQAKRLYTTNADGELLTID-SESNTiasrKKLQDDGKAHFYLNLS 237
Cdd:cd20718  126 ILDADTLEPLKVIPTTGVnddgiiesrVGAILETPPGPYFLVALKDAGSVWVIDySDPDG----NKVTDIGNIGRPLHDA 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 238 LDTAGHRAFITDSKQPEVL-VVDTRDGKVLEKIAA-----PESLAVLFNpaRNEAYVTHRKAGEVSVIDGKSYKVVKTFK 311
Cdd:cd20718  202 FLDPDGRYFIVASQGSNTMwVLDLKTGKVVARIPTgktphPGPGATWGR--KGVTATPHLGEGIVTVWDLDTWKPVKYIP 279

                        170
                 ....*....|....
gi 488996073 312 TP-------THPNS 318
Cdd:cd20718  280 TPgpgrfvrTHPSS 293
8prop_hemeD1_NirF cd20778
eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; ...
 241-332 3.62e-04

eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; Denitrification is a process that enables biofilm formation of the opportunistic human pathogen Pseudomonas aeruginosa, making it more resilient to antibiotics and highly adaptable to different habitats. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO3- -> NO2- -> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic cytochrome cd1 (nitrite reductase) NirS via its maturation factor NirF. The nirFDLGHJE genes encode proteins required for heme d1 biosynthesis. NirS, NirF, and NirN, the monomeric dihydro-heme d1 dehydrogenase form a stable complex during nitrite reductase maturation. The nitrite reductase NirS is bound to the denitrification supercomplex via NorB, while the electron donor system NirM and the enzyme maturation machinery NirN-NirF-NirQ, interacting with NirS, are bound via NorC.


Pssm-ID: 467722 [Multi-domain]  Cd Length: 381  Bit Score: 41.89  E-value: 3.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 241 AGHRAFITDSKQPEVLVVDTRDGKVLEKIA-APESLAVLFNPARNEAYVT--HRKAGEVSVIDGKSYKVVKTFKTP---T 314
Cdd:cd20778  249 AGDKAFVPAVGEHRVLVYDTNDWKFIKSIPlAGQPVFAVARPDGRYVWVNfsGPDNDTVQVIDTKTLKVVKTLEPGkrvL 328

                         90
                 ....*....|....*...
gi 488996073 315 HpnsLALSEDGKTLYVSV 332
Cdd:cd20778  329 H---MEFTPRGEAVYISV 343
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 186-331 5.78e-04

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 41.03  E-value: 5.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 186 MATGLAIDPqAKRLYTTN-ADGELLTIDSESNTIASRkkLQDDGKAHFylnLSLDTAGhRAFITDSKqPEVLVVDTRDGK 264
Cdd:COG3386    9 LGEGPVWDP-DGRLYWVDiPGGRIHRYDPDGGAVEVF--AEPSGRPNG---LAFDPDG-RLLVADHG-RGLVRFDPADGE 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488996073 265 VlEKIAAPESLA------VLFNPARNeAYVT----HRKAGEVSVI--DGKSYKVVKTFktpTHPNSLALSEDGKTLYVS 331
Cdd:COG3386   81 V-TVLADEYGKPlnrpndGVVDPDGR-LYFTdmgeYLPTGALYRVdpDGSLRVLADGL---TFPNGIAFSPDGRTLYVA 154
WD40 COG2319
WD40 repeat [General function prediction only];
166-331 1.85e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 39.89  E-value: 1.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 166 IWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDSESNTIasRKKLQDDGKAHFYLNLSLDtaGHRa 245
Cdd:COG2319  186 VRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKL--LRTLTGHSGSVRSVAFSPD--GRL- 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 246 FITDSKQPEVLVVDTRDGKVLEKIAAPES--LAVLFNPaRNEAYVTHRKAGEVSVIDGKSYKVVKTFKTPTHP-NSLALS 322
Cdd:COG2319  261 LASGSADGTVRLWDLATGELLRTLTGHSGgvNSVAFSP-DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAvRSVAFS 339


                 ....*....
gi 488996073 323 EDGKTLYVS 331
Cdd:COG2319  340 PDGKTLASG 348
beta_rpt_yvtn TIGR02276
40-residue YVTN family beta-propeller repeat; This repeat of about 40 amino acids is found in ...
 281-322 3.53e-03

40-residue YVTN family beta-propeller repeat; This repeat of about 40 amino acids is found in up to 14 copies per protein. Archaea Methanosarcina mazei and Methanosarcina acetivorans each have over 10 genes that encode tandem copies of this repeat, which is also found in other species. PSIPRED predicts with high confidence that each 40-residue repeats contains four beta strands. This model overlaps somewhat with the NHL repeat (pfam01436) and also shows sequence similarity to the WD domain, G-beta repeat (pfam00400).


Pssm-ID: 213697 [Multi-domain]  Cd Length: 42  Bit Score: 34.96  E-value: 3.53e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 488996073  281 PARNEAYVTHRKAGEVSVIDGKSYKVVKTFKTPTHPNSLALS 322
Cdd:TIGR02276   1 PDGTKLYVTNSGSNTVSVIDTATNKVIATIPVGGYPFGVAVS 42
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 142-337 5.35e-03

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 38.36  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  142 QPRELAVNEQTNTVY-ITGLGKESVIWVV----DGATLKLKTTITGTGAMATGLAIDPQAKRLYTTN------------A 204
Cdd:pfam10282  38 NPSYLALSPDGRTLYaVNEEGDQGGVAAFridpDSGALTLLNQVPTGGASPCHLSVDPDGRFLFVANyhggsvsvfpldA 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  205 DGELLTIDSESNTIAS--RKKLQDDGKAHFylnLSLDTAGHRAFITDSKQPEVLV--VDTRDGKvLEKIAA--------P 272
Cdd:pfam10282 118 DGSLGELSQVVQHEGSgpPPERQESPHPHS---VDLTPDGKFLVVPDLGTDRVRVykLDAGGGK-LTPPASvqtppgsgP 193

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488996073  273 ESLAvlFNPARNEAYVTHRKAGEVSV--IDGKSYKVVKTFKTPTHP------NSLA---LSEDGKTLYVSVKQASS 337
Cdd:pfam10282 194 RHLA--FHPNGKYAYVVNELSSTVTVfeYDPATGTFEELQTVSTLPegftgtNGAAairVSPDGKFLYVSNRGHDS 267
WD40 COG2319
WD40 repeat [General function prediction only];
94-328 5.71e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 38.35  E-value: 5.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073  94 ATINHATGTLWFGNTVDSTVTAIDAKTGAVKGRLVLDERQRSETVRPLQPRELAVNEQTNTVYITGLGKESVIWVVDGAT 173
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLAT 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 174 LKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDsesntIASRKKLQD-DGKAHFYLNLSLDTAGHRaFITDSKQ 252
Cdd:COG2319  110 GLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD-----LATGKLLRTlTGHSGAVTSVAFSPDGKL-LASGSDD 183

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488996073 253 PEVLVVDTRDGKVLEKIAAPES--LAVLFNPaRNEAYVTHRKAGEVSVIDGKSYKVVKTFKTPTHP-NSLALSEDGKTL 328
Cdd:COG2319  184 GTVRLWDLATGKLLRTLTGHTGavRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSvRSVAFSPDGRLL 261
COG5276 COG5276
Uncharacterized secreted protein, contains LVIVD repeats, choice-of-anchor domain [Function ...
 153-331 8.08e-03

Uncharacterized secreted protein, contains LVIVD repeats, choice-of-anchor domain [Function unknown];


Pssm-ID: 444087 [Multi-domain]  Cd Length: 320  Bit Score: 37.61  E-value: 8.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 153 NTVYITGLGKESVIW--VVDGATLKLKTTITGTGAMATGLAIDPqaKRLYTT-NADGELLTID---SESNTIASRKKLQD 226
Cdd:COG5276   73 DYLYVASEGSEGLQIfdISDPANPKLVGRYDTGGSGAHNIAVDG--NYAYVAgGSDNGLVIVDisdPTNPVLVGRYSLPG 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 227 DGKAHfylnlSLDTAGHRAFITDsKQPEVLVVDTRDgkvlekIAAPESL------------AVLFNPARNEAYVTHRKAG 294
Cdd:COG5276  151 QAYLH-----DVQVVGDYAYVAD-WEDGLVIVDVSD------PSNPKLIgsydysppgythTAVPVEDGNYAYVGDELGG 218

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488996073 295 E-----VSVIDGKSYKVVKTFKTPTHPNSLALSEDGKTLYVS 331
Cdd:COG5276  219 PnglriLDVSDPANPVLIGTYPTPGADGAHNLYVSGNYLYVA 260
WD40 COG2319
WD40 repeat [General function prediction only];
166-328 9.34e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 37.58  E-value: 9.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 166 IWVVDGATLKLKTTITGTGAMATGLAIDPQAKRLYTTNADGELLTIDSESNTIasRKKLQDDGKAHFYLNLSLDtaGHRa 245
Cdd:COG2319  228 VRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGEL--LRTLTGHSGGVNSVAFSPD--GKL- 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488996073 246 FITDSKQPEVLVVDTRDGKVLEKIAAPES--LAVLFNPARNEAYVTHRKaGEVSVIDGKSYKVVKTFKTPTHP-NSLALS 322
Cdd:COG2319  303 LASGSDDGTVRLWDLATGKLLRTLTGHTGavRSVAFSPDGKTLASGSDD-GTVRLWDLATGELLRTLTGHTGAvTSVAFS 381


                 ....*.
gi 488996073 323 EDGKTL 328
Cdd:COG2319  382 PDGRTL 387
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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