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Conserved domains on  [gi|488997124|ref|WP_002907825|]
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MULTISPECIES: ABC transporter permease [Klebsiella]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-318 6.18e-124

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 357.46  E-value: 6.18e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNI--TLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFS 78
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgpRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  79 LQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLH 158
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 159 WLPVGGMTntgsdeSGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRN 238
Cdd:COG0601  161 WLPVSGRV------SPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRN 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 239 ALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVR 318
Cdd:COG0601  235 ALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-318 6.18e-124

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 357.46  E-value: 6.18e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNI--TLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFS 78
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgpRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  79 LQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLH 158
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 159 WLPVGGMTntgsdeSGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRN 238
Cdd:COG0601  161 WLPVSGRV------SPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRN 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 239 ALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVR 318
Cdd:COG0601  235 ALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-316 3.46e-65

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 207.63  E-value: 3.46e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGD-FID----GNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDL 75
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDpALDylrlSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  76 GFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAV 155
Cdd:PRK10352  81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 156 DLHWLPVGGmtntgsdESGWQyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHA 235
Cdd:PRK10352 161 YLQWLPAMG-------YGGWQ-------HIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHI 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 236 LRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRI 315
Cdd:PRK10352 227 LRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRI 306


                 .
gi 488997124 316 R 316
Cdd:PRK10352 307 R 307
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 1-316 2.52e-63

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 203.07  E-value: 2.52e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124    1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFID-----GNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDL 75
Cdd:TIGR02789   1 MLNYILRRLLLLIPVVLAASLLAFILIHLGPSDPAEdylrlSHIPPTDEAIADMRHSLGLDQPLYVQYFHWLWNALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   76 GFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAV 155
Cdd:TIGR02789  81 GISYISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  156 DLHWLPVGGmtntgsdESGWQyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHA 235
Cdd:TIGR02789 161 YLNLLPTNG-------AGTWQ-------HLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHI 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  236 LRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRI 315
Cdd:TIGR02789 227 LRNAILPMITALGMHIGELLGGTFVIENIFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRI 306


                  .
gi 488997124  316 R 316
Cdd:TIGR02789 307 R 307
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-317 9.78e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 103.53  E-value: 9.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  111 GLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFavdlhwlpvggmtntgsdesgwqyVLQVAAHLALPVL 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------ILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  191 ALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFELPGLFSGAIITEKVFNWPGA 270
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 488997124  271 GHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRV 317
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-306 5.47e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.53  E-value: 5.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  93 IWNSFLLASVALVFYWGIGLAVGVVSALRPGsWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWLPVGgmtntgsde 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP--------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 173 sgwqyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFELP 252
Cdd:cd06261   71 -----------GLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 488997124 253 GLFSGAIITEKVFNWPGAGhihIDSLAARDYPVLMGFTLFLAVLTIVGNLLADV 306
Cdd:cd06261  140 RALGEFALVSFLGGGEAPG---PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-318 6.18e-124

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 357.46  E-value: 6.18e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNI--TLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFS 78
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgpRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  79 LQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLH 158
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 159 WLPVGGMTntgsdeSGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRN 238
Cdd:COG0601  161 WLPVSGRV------SPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRN 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 239 ALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVR 318
Cdd:COG0601  235 ALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-316 3.46e-65

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 207.63  E-value: 3.46e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGD-FID----GNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDL 75
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDpALDylrlSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  76 GFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAV 155
Cdd:PRK10352  81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 156 DLHWLPVGGmtntgsdESGWQyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHA 235
Cdd:PRK10352 161 YLQWLPAMG-------YGGWQ-------HIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHI 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 236 LRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRI 315
Cdd:PRK10352 227 LRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRI 306


                 .
gi 488997124 316 R 316
Cdd:PRK10352 307 R 307
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 1-316 2.52e-63

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 203.07  E-value: 2.52e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124    1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFID-----GNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDL 75
Cdd:TIGR02789   1 MLNYILRRLLLLIPVVLAASLLAFILIHLGPSDPAEdylrlSHIPPTDEAIADMRHSLGLDQPLYVQYFHWLWNALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   76 GFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAV 155
Cdd:TIGR02789  81 GISYISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  156 DLHWLPVGGmtntgsdESGWQyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHA 235
Cdd:TIGR02789 161 YLNLLPTNG-------AGTWQ-------HLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHI 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  236 LRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRI 315
Cdd:TIGR02789 227 LRNAILPMITALGMHIGELLGGTFVIENIFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRI 306


                  .
gi 488997124  316 R 316
Cdd:TIGR02789 307 R 307
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-316 5.82e-63

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 201.87  E-value: 5.82e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGD---FIDGNiTLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGF 77
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDparLAAGP-EADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  78 SLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDL 157
Cdd:PRK15081  80 SMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVEL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 158 HWLPVGGmtntgsdESGWQyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALR 237
Cdd:PRK15081 160 GWLPTVG-------ADSWQ-------HYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLR 225

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488997124 238 NALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIR 316
Cdd:PRK15081 226 NAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-316 2.29e-59

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 192.59  E-value: 2.29e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQ 80
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  81 YQ-IPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHW 159
Cdd:PRK09471  81 YKdYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 160 LPVGGMtntgsDESGWQYVLqvaahlaLPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNA 239
Cdd:PRK09471 161 LPGGGW-----NGGALKFMI-------LPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPA 228

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488997124 240 LLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIR 316
Cdd:PRK09471 229 LLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-316 1.87e-58

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 191.18  E-value: 1.87e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124   1 MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGD---FIDGNITLTSARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGF 77
Cdd:PRK10914   1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDpvmIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  78 SLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDL 157
Cdd:PRK10914  81 SLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 158 HWLPVGGMTNTGS--DES----GWQYV-----------LQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTA 220
Cdd:PRK10914 161 NLTPVSGRVSDMVflDDSnpltGFMLIdtaiwgedgnfIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 221 RAKGLQERTVILKHALRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVG 300
Cdd:PRK10914 241 RAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV 320

                        330
                 ....*....|....*.
gi 488997124 301 NLLADVLYAWADPRIR 316
Cdd:PRK10914 321 NLLVDLLYGVVNPRIR 336
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 47-315 1.63e-45

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 158.04  E-value: 1.63e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  47 AELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQYQIPVSQLLNQY--------IWnSFLLAsvalvfyWGIGLAVGVVS 118
Cdd:COG4174   84 AELEKQYGFDKPAHERFLLMLKNYLRFDFGESYFRDISVIDLILEKlpvsislgLW-STLLT-------YLISIPLGIRK 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 119 ALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVD--LHWLPVGGMTNTGSDE-SGWQYVLQVAAHLALPVLALVML 195
Cdd:COG4174  156 AVRDGSRFDVWTSTVIIVGYAIPGFLFAILLIVLFAGGsyFDWFPLRGLTSDNWDQlSWWGKILDYLWHLTLPVTAMVIG 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 196 QAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITllGFelPG-----LFSGAIITEKVFNWPGA 270
Cdd:COG4174  236 GFATLTLLTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIA--GF--PAafigaFFTGSLLIETIFSLDGL 311

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 488997124 271 GHIHIDSLAARDYPVLMGfTLFL-AVLTIVGNLLADVLYAWADPRI 315
Cdd:COG4174  312 GLLGFEAVVNRDYPVVFG-TLYIfTLIGLVLKLISDLTYVLVDPRI 356
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 47-315 4.21e-36

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 133.33  E-value: 4.21e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  47 AELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWF 126
Cdd:PRK15133  87 AEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRF 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 127 DHLVSVAVFAAMSFPTFFLCLLLIKWFAVD--LHWLPVGGMTNTGSDESGW-QYVLQVAAHLALPVLALVMLQAGSLTRY 203
Cdd:PRK15133 167 DVWSSAFIIIGYAIPAFLFAILLIVFFAGGsyFDLFPLRGLVSANFDSLPWyQKITDYLWHITLPVLATVIGGFAALTML 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 204 VRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITllGFE---LPGLFSGAIITEKVFNWPGAGHIHIDSLAA 280
Cdd:PRK15133 247 TKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIA--GFPatfISMFFTGSLLIEVMFSLNGLGLLGYEATVS 324

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 488997124 281 RDYPVLMGfTLFlaVLTIVG---NLLADVLYAWADPRI 315
Cdd:PRK15133 325 RDYPVMFG-TLY--IFTLIGlllNIVSDISYTLVDPRI 359
PRK15110 PRK15110
peptide ABC transporter permease SapB;
59-313 2.66e-33

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 124.80  E-value: 2.66e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  59 LLTRYLHWLGQLLRGDLGFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAM 138
Cdd:PRK15110  40 LWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGF 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 139 SFPTFFLCLLLIKWFAVDLHWLPVGGMTN--------TGS-------DESGW--QYVLQVAAHLALPVLALVMLQAGSLT 201
Cdd:PRK15110 120 SIPVFWLALLLTLFFSLTLGWLPVSGRFDllyevkpvTGFalidawlSDSPWrdEMIMSAIRHMILPVITLAVAPTTEVI 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 202 RYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAAR 281
Cdd:PRK15110 200 RLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQ 279

                        250       260       270
                 ....*....|....*....|....*....|..
gi 488997124 282 DYPVLMGFTLFLAVLTIVGNLLADVLYAWADP 313
Cdd:PRK15110 280 DYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-317 9.78e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 103.53  E-value: 9.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  111 GLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFavdlhwlpvggmtntgsdesgwqyVLQVAAHLALPVL 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------ILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  191 ALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFELPGLFSGAIITEKVFNWPGA 270
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 488997124  271 GHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRV 317
Cdd:pfam00528 137 GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-306 5.47e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.53  E-value: 5.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  93 IWNSFLLASVALVFYWGIGLAVGVVSALRPGsWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWLPVGgmtntgsde 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP--------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 173 sgwqyvlqvaaHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFELP 252
Cdd:cd06261   71 -----------GLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFA 139

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 488997124 253 GLFSGAIITEKVFNWPGAGhihIDSLAARDYPVLMGFTLFLAVLTIVGNLLADV 306
Cdd:cd06261  140 RALGEFALVSFLGGGEAPG---PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 93-262 3.59e-09

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 3.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124  93 IWNSFLLASVALVFYWGIGLAVGVVSALRPGsWFDHLVSVAVFAAMSFPTFFLCLLLIkwfavdlhwlpvgGMTNTGsde 172
Cdd:COG1173   78 ARISLLVGLLAVLIALVIGVLLGLLAGYFGG-WVDAVLMRLVDVLLAFPSLLLAIALV-------------AVLGPG--- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 173 sgwqyvlqvaahLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFelp 252
Cdd:COG1173  141 ------------LLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATL--- 205

                        170
                 ....*....|
gi 488997124 253 gLFSGAIITE 262
Cdd:COG1173  206 -GIASAILAE 214
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 132-251 3.96e-05

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 44.59  E-value: 3.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488997124 132 VAVFAAMsfPTFFLCLLLIKWFAVDLHWLpvggmtntgsdesgwqyvlqvaahLALPVLALVMlqagSLTRYVRASMLDV 211
Cdd:PRK15021 180 IEVWSGM--PTLFLIILLSSVVQPNFWWL------------------------LAITVLFGWM----SLVGVVRAEFLRT 229

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 488997124 212 VKMDFIRTARAKGLQERTVILKHALRNALLPIITLLGFEL 251
Cdd:PRK15021 230 RNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFIL 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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