|
Name |
Accession |
Description |
Interval |
E-value |
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
2-393 |
7.90e-127 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 373.39 E-value: 7.90e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 2 HDRRLAARAGELKPSAVRELLKHSklPGVISLGGGIPAPELFDTEGLELAVQKVMSERFNDAFQYGLTEGYPPLRQAVSE 81
Cdd:COG1167 82 APAPAPRAAAAVAAPALRRLLEAA--PGVIDLGSGAPDPDLFPLAALRRALRRALRRLPPALLGYGDPQGLPELREAIAR 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 82 ICHSRGVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLET 161
Cdd:COG1167 160 YLARRGVPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDEDGLDLDALEAALRR 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 162 TRVKAVYLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYqhavELSCEDQVVYTSTFSKI 241
Cdd:COG1167 240 HRPRAVYVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLA----ALDAPGRVIYIGSFSKT 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 242 LAPGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVITAEYLSLNRLDNQIALIREDYRKKCVALADALESRLGEHLEF 321
Cdd:COG1167 316 LAPGLRLGYLVAPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLRV 395
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489006153 322 SRPQGGMFLWARFRYPFDTMEWMKKTLENGVVYVPGEAFYHDKPDTRTLRLSYSTVSEAGLLTAVERLAASL 393
Cdd:COG1167 396 TGPPGGLHLWLELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELL 467
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
31-391 |
7.72e-85 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 261.89 E-value: 7.72e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 31 ISLGGGIPAPELFDTEGLELAvqkvMSERFNDAFQYGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVA 109
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALA----AAALRAGLLGYYPDPGLPELREAIAEWLGRRgGVDVPPEEIVVTNGAQEALSLLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 110 RTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLE--TTRVKAVYLVPtFGNPGGKTLSEARRR 187
Cdd:cd00609 77 RALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAakTPKTKLLYLNN-PNNPTGAVLSEEELE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 188 RLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQhaveLSCEDQVVYTSTFSKILA-PGMRIGWIVMPD-WLAQQTVIVK 265
Cdd:cd00609 156 ELAELAKKHGILIISDEAYAELVYDGEPPPALAL----LDAYERVIVLRSFSKTFGlPGLRIGYLIAPPeELLERLKKLL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 266 QAADLHTNMLSQVITAEYlsLNRLDNQIALIREDYRKKCVALADALESRLGEHleFSRPQGGMFLWARFRYPFDTMEWMK 345
Cdd:cd00609 232 PYTTSGPSTLSQAAAAAA--LDDGEEHLEELRERYRRRRDALLEALKELGPLV--VVKPSGGFFLWLDLPEGDDEEFLER 307
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489006153 346 KTLENGVVYVPGEAFYHDKPdtRTLRLSYSTvSEAGLLTAVERLAA 391
Cdd:cd00609 308 LLLEAGVVVRPGSAFGEGGE--GFVRLSFAT-PEEELEEALERLAE 350
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
5-393 |
3.34e-65 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 212.68 E-value: 3.34e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 5 RLAARAGELKPSAVRELLKHSKL-----PGVISLGGG---IPAPElfdtEGLElAVQKVMSERFNdafQYGLTEGYPPLR 76
Cdd:COG0436 2 KLSSRLARLPPSPIREVSALAAElkaagEDVIDLGIGepdFPTPD----HIRE-AAIEALDDGVT---GYTPSAGIPELR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 77 QAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTD-DDGML--V 152
Cdd:COG0436 74 EAIAAYYKRRyGVDLDPDEILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDeENGFLpdP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 153 EQLADLLeTTRVKAVYLV-PtfGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAvELSceDQ 231
Cdd:COG0436 154 EALEAAI-TPRTKAIVLNsP--NNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLP-GLK--DR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 232 VVYTSTFSKILA-PGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVITAEYlsLNRLDNQIALIREDYRKKCVALADA 310
Cdd:COG0436 228 TIVINSFSKSYAmTGWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAA--LEGPQDYVEEMRAEYRRRRDLLVEG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 311 LEsRLGehLEFSRPQGGMFLWARFRYPFDT-MEWMKKTLEN-GVVYVPGEAFYHDKPDtrTLRLSYsTVSEAGLLTAVER 388
Cdd:COG0436 306 LN-EIG--LSVVKPEGAFYLFADVPELGLDsEEFAERLLEEaGVAVVPGSAFGPAGEG--YVRISY-ATSEERLEEALER 379
|
....*
gi 489006153 389 LAASL 393
Cdd:COG0436 380 LARFL 384
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
4-391 |
3.70e-35 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 133.33 E-value: 3.70e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 4 RRLAARAGELKPSAVRELL---KHSKLPG--VISLGGGIPApelFDT-EGLELAVQKVMSERFNdafQYGLTEGYPPLRQ 77
Cdd:PRK05764 2 MKLSKRVSRVTPSATLAVTakaKELKAQGrdVISLGAGEPD---FDTpEHIKEAAIEALDDGKT---KYTPAAGIPELRE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 78 AVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTD-DDGML--VE 153
Cdd:PRK05764 76 AIAAKLKRDnGLDYDPSQVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGeENGFKltVE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 154 QLADLLeTTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAVELSceDQVV 233
Cdd:PRK05764 156 QLEAAI-TPKTKAL-ILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLSPELR--DRTI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 234 YTSTFSKILA-PGMRIGWIVMPDWlaqqtvIVKQAADLHTNMLSQVIT-AEYLS---LNRLDNQIALIREDYRKKCvala 308
Cdd:PRK05764 232 TVNGFSKAYAmTGWRLGYAAGPKE------LIKAMSKLQSHSTSNPTSiAQYAAvaaLNGPQDEVEEMRQAFEERR---- 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 309 DALESRLGEH--LEFSRPQGGMFLWAR-----FRYPFDTMEWMKKTLEN-GVVYVPGEAFyhdkPDTRTLRLSYSTvSEA 380
Cdd:PRK05764 302 DLMVDGLNEIpgLECPKPEGAFYVFPNvskllGKSITDSLEFAEALLEEaGVAVVPGIAF----GAPGYVRLSYAT-SLE 376
|
410
....*....|.
gi 489006153 381 GLLTAVERLAA 391
Cdd:PRK05764 377 DLEEGLERIER 387
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
6-393 |
4.51e-31 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 121.91 E-value: 4.51e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 6 LAARAGELKPSAVRELL-KHSKLPGVISLGGGIPApelFDT-EGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSEIC 83
Cdd:PRK08361 10 IAGRINLIQRSKIRELFeRASKMENVISLGIGEPD---FDTpKNIKEAAKRALDEGWT---HYTPNAGIPELREAIAEYY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 84 HS-RGVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLETT 162
Cdd:PRK08361 84 KKfYGVDVDVDNVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREENEFQPDPDELLELI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 163 RVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAvelscEDQVVYTSTFSKI 241
Cdd:PRK08361 164 TKRTRMIVINYpNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYA-----PDNTILANSFSKT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 242 LA-PGMRIGWIVMPdwlaqqTVIVKQAADLHT----NMLS--QVITAEYLSLNRLDNQIALIREDY--RKKCVAladale 312
Cdd:PRK08361 239 FAmTGWRLGFVIAP------EQVIKDMIKLHAyiigNVASfvQIAGIEALRSKESWKAVEEMRKEYneRRKLVL------ 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 313 SRLGE--HLEFSRPQGGMFLWARFR----YPFDTMEWMkktLEN-GVVYVPGEAFyhDKPDTRTLRLSYSTvSEAGLLTA 385
Cdd:PRK08361 307 KRLKEmpHIKVFEPKGAFYVFANIDetgmSSEDFAEWL---LEKaRVVVIPGTAF--GKAGEGYIRISYAT-SKEKLIEA 380
|
....*...
gi 489006153 386 VERLAASL 393
Cdd:PRK08361 381 MERMEKAL 388
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
60-389 |
7.21e-30 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 117.79 E-value: 7.21e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 60 FNDAFQYGLTEGYPPLRQAVSEICHSRGVACSAAQVYI--TSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQ 137
Cdd:pfam00155 29 GGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVvfGSGAGANIEALIFLLANPGDAILVPAPTYASYIRIARLAG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 138 ANILSV---DTDDDGMLVEQLADLLEtTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDA 214
Cdd:pfam00155 109 GEVVRYplyDSNDFHLDFDALEAALK-EKPKVV-LHTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSP 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 215 VRRPLYqhaVELSCEDQVVYTSTFSKILA-PGMRIGWIVMPDWlaqqtvIVKQAADLHTNMLSQVITAEYLsLNRLDNQI 293
Cdd:pfam00155 187 DAVATR---ALLAEGPNLLVVGSFSKAFGlAGWRVGYILGNAA------VISQLRKLARPFYSSTHLQAAA-AAALSDPL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 294 ALIRE--DYRKKCVALADALESRLGEH-LEFSRPQGGMFLWARFRyPFDTMEWMKKTLENGVVYV-PGEAFYHdkpdTRT 369
Cdd:pfam00155 257 LVASEleEMRQRIKERRDYLRDGLQAAgLSVLPSQAGFFLLTGLD-PETAKELAQVLLEEVGVYVtPGSSPGV----PGW 331
|
330 340
....*....|....*....|
gi 489006153 370 LRLSYSTVSEAGLLTAVERL 389
Cdd:pfam00155 332 LRITVAGGTEEELEELLEAI 351
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
9-389 |
2.73e-28 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 114.44 E-value: 2.73e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 9 RAGELKPSAVRELLKH-SKLPGVISLGggIPAPELFDTEGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSEICHSR- 86
Cdd:PRK07683 8 RVKDIQISGIRQFSNMvQNYDNLISLT--IGQPDFPTPSHVKEAAKRAITENYT---SYTHNAGLLELRKAACNFVKDKy 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 87 GVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDG--MLVEQLADLLeTTR 163
Cdd:PRK07683 83 DLHYSPeSEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTRSTGfrLTAEALENAI-TEK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 164 VKAVYLvPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTdavrRPLYQHAVELSCEDQVVYTSTFSKILA 243
Cdd:PRK07683 162 TRCVVL-PYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYE----QPHTSIAHFPEMREKTIVINGLSKSHS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 244 -PGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVITAEYLSLNRLDNQIalIREDYRKKCVALADALESrLGehLEFS 322
Cdd:PRK07683 237 mTGWRIGFLFAPSYLAKHILKVHQYNVTCASSISQYAALEALTAGKDDAKM--MRHQYKKRRDYVYNRLIS-MG--LDVE 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489006153 323 RPQGGMFLW---ARFRYP-FD-TMEWMKKTlenGVVYVPGEAFYHdkPDTRTLRLSYSTvSEAGLLTAVERL 389
Cdd:PRK07683 312 KPTGAFYLFpsiGHFTMSsFDfALDLVEEA---GLAVVPGSAFSE--YGEGYVRLSYAY-SIETLKEGLDRL 377
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
25-391 |
6.64e-25 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 104.81 E-value: 6.64e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 25 SKLPGVISLGGGIPApelFDT-EGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSEICHSR-GVACSAA-QVYITSGS 101
Cdd:PRK07309 27 SDIPGILKLTLGEPD---FTTpDHVKEAAKRAIDANQS---HYTGMAGLLELRQAAADFVKEKyNLDYAPEnEILVTIGA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 102 QQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEqlADLLETT------RVKAVYL-VPTfg 174
Cdd:PRK07309 101 TEALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDFVLT--PEMLEKAileqgdKLKAVILnYPA-- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 175 NPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAvelscEDQVVYTSTFSKILA-PGMRIGWIVM 253
Cdd:PRK07309 177 NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEYL-----PDQTILINGLSKSHAmTGWRIGLIFA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 254 PDWLAQQTVIVKQAADLHTNMLSQVITAEYLSLNRLDNQIalIREDYRKKCVALADALeSRLGehLEFSRPQGGMFLWAR 333
Cdd:PRK07309 252 PAEFTAQLIKSHQYLVTAATTMAQFAAVEALTNGKDDALP--MKKEYIKRRDYIIEKM-TDLG--FKIIKPDGAFYIFAK 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489006153 334 F--RYPFDTMEWMKK-TLENGVVYVPGEAFyhDKPDTRTLRLSYSTvSEAGLLTAVERLAA 391
Cdd:PRK07309 327 IpaGYNQDSFKFLQDfARKKAVAFIPGAAF--GPYGEGYVRLSYAA-SMETIKEAMKRLKE 384
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
28-390 |
1.10e-22 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 98.77 E-value: 1.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 28 PGVISLGGGIPA--PElfdteglelavqkvMSERFNDAFQ--------------YGLTEGYPPLRQAVSEICHSR-GVAC 90
Cdd:PRK09440 30 PGAIMLGGGNPAhiPE--------------MEDYFRDLLAdllasgkltealgnYDGPQGKDELIEALAALLNERyGWNI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 91 SAAQVYITSGSQQSLDIVARTLLDPGDTIVVER------PTYL----AAL--QVFQLAQANIlsvDTDDDGML-----VE 153
Cdd:PRK09440 96 SPQNIALTNGSQSAFFYLFNLFAGRRADGSLKKilfplaPEYIgyadAGLeeDLFVSYRPNI---ELLPEGQFkyhvdFE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 154 QLaDLLETTrvkAVYLV--PTfgNPGGKTLSEARRRRLVELAKKYDFVILEDDPYG----EISFTDAvrRPLYqhavels 227
Cdd:PRK09440 173 HL-HIDEDT---GAICVsrPT--NPTGNVLTDEELEKLDALARQHNIPLLIDNAYGppfpGIIFSEA--TPLW------- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 228 cEDQVVYTSTFSKILAPGMRIGWIVMPDWLAQ-----QTVIVkqaadLHTNMLSQVITAEYL---SLNRLDNQIalIRED 299
Cdd:PRK09440 238 -NPNIILCMSLSKLGLPGVRCGIVIADEEIIEalsnmNGIIS-----LAPGRLGPAIAAEMIesgDLLRLSETV--IRPF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 300 YRKKcVALADA-LESRLGE-----HlefsRPQGGMFLWARFR-YPFDTMEWMKKTLENGVVYVPGEAFYH----DKPDTR 368
Cdd:PRK09440 310 YRQK-VQLAIAlLRRYLPDepcliH----KPEGAIFLWLWFKdLPITTEELYQRLKARGVLVVPGHYFFPgldeDWPHAH 384
|
410 420
....*....|....*....|...
gi 489006153 369 T-LRLSYsTVSEAGLLTAVERLA 390
Cdd:PRK09440 385 QcIRMNY-VQDDEEIEKGIAILA 406
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
32-391 |
2.46e-20 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 91.79 E-value: 2.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 32 SLGG-GIPAPELFDTeglelAVQKVMSERFNDAFQYGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVA 109
Cdd:PRK06836 39 SLGNpSVPPPAAVKE-----ALRELAEEEDPGLHGYMPNAGYPEVREAIAESLNRRfGTPLTADHIVMTCGAAGALNVAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 110 RTLLDPGDTIVVERPtYLAALQVF-QLAQANILSVDTDDDGML--VEQLADLLeTTRVKAVyLVPTFGNPGGKTLSEARR 186
Cdd:PRK06836 114 KAILNPGDEVIVFAP-YFVEYRFYvDNHGGKLVVVPTDTDTFQpdLDALEAAI-TPKTKAV-IINSPNNPTGVVYSEETL 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 187 RRLVEL----AKKYDFVI--LEDDPYGEISFtDAVRRP----LYQHAVelscedqVVYtsTFSKILA-PGMRIGWIVMPD 255
Cdd:PRK06836 191 KALAALleekSKEYGRPIylISDEPYREIVY-DGAEVPyifkYYDNSI-------VVY--SFSKSLSlPGERIGYIAVNP 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 256 WLAQQTVIVkqAADLHTN----------MLSQVITaeylslnRLDNQIALIrEDYRKKCVALADALeSRLGehLEFSRPQ 325
Cdd:PRK06836 261 EMEDADDLV--AALVFANrilgfvnapaLMQRVVA-------KCLDATVDV-SIYKRNRDLLYDGL-TELG--FECVKPQ 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489006153 326 GGMFLWARFRYPfDTMEWMKKTLENGVVYVPGEAF----YhdkpdtrtLRLSYStVSEAGL---LTAVERLAA 391
Cdd:PRK06836 328 GAFYLFPKSPEE-DDVAFCEKAKKHNLLLVPGSGFgcpgY--------FRLSYC-VDTETIersLPAFEKLAK 390
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
17-391 |
4.53e-20 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 90.86 E-value: 4.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 17 AVRELLKHSKLPG--VISLGGGIPAPE---LFDTEGLELAVQKVMSERFNDafqYGLTEGYPPLRQAVSEICHSRGVA-C 90
Cdd:TIGR01265 18 AIVDNLKVKPNPEkpVIPLSHGDPSVFgnlRTDPEAEEAVKDALRSGKFNG---YAPSVGALAAREAVAEYLSSDLPGkL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 91 SAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY-----LAALQVFQLAQANIL---SVDTDDDGMlvEQLADllETT 162
Cdd:TIGR01265 95 TADDVVLTSGCSQAIEICIEALANPGANILVPRPGFplydtRAAFSGLEVRLYDLLpekDWEIDLDGL--ESLAD--EKT 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 163 rvkAVYLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLyqhaVELSCEDQVVYTSTFSK-I 241
Cdd:TIGR01265 171 ---VAIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPM----ASFASIVPVLSLGGISKrW 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 242 LAPGMRIGWIVMPDwlaQQTVIVKQAADLHTNMLSQVITAEYLSLNRLDNQIALIREDYRKKCVAL----ADALESRLGE 317
Cdd:TIGR01265 244 VVPGWRLGWIIIHD---PHGIFRDTVLQGLKNLLQRILGPATIVQGALPDILENTPQEFFDGKISVlksnAELCYEELKD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 318 --HLEFSRPQGGMFLW-----ARFRYPFDTMEWMKKTL-ENGVVYVPGEAFyhDKPDtrTLRLSYsTVSEAGLLTAVERL 389
Cdd:TIGR01265 321 ipGLVCPKPEGAMYLMvklelELFPEIKDDVDFCEKLArEESVICLPGSAF--GLPN--WVRITI-TVPESMLEEACSRI 395
|
..
gi 489006153 390 AA 391
Cdd:TIGR01265 396 KE 397
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
52-360 |
6.02e-20 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 90.64 E-value: 6.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 52 VQKVMSERFNDAFQYGLT-EGYPPLRQAVSEICHSR-GVACSAA-QVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLA 128
Cdd:PRK07681 50 VREEMVHTANQKESYGYTlSGIQEFHEAVTEYYNNThNVILNADkEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 129 ALQVFQLAQANILSVDTDDDGMLVEQLADLLETTRVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYG 207
Cdd:PRK07681 130 YETGIQMAGATSYYMPLKKENDFLPDLELIPEEIADKAKMMILNFpGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 208 EISFTDavRRPLYQHAVELSCEDQVVYTSTFSKILAPGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVITAEylSLN 287
Cdd:PRK07681 210 EFYFDG--NKPISFLSVPGAKEVGVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKSNTDYGVFLPIQKAACA--ALR 285
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489006153 288 RLDNQIALIREDYRKKCVALADALESrLGehLEFSRPQGGMFLWARFRYPFDTMEWMKKTLEN-GVVYVPGEAF 360
Cdd:PRK07681 286 NGAAFCEKNRGIYQERRDTLVDGFRT-FG--WNVDKPAGSMFVWAEIPKGWTSLSFAYALMDRaNVVVTPGHAF 356
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
53-360 |
9.49e-20 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 89.78 E-value: 9.49e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 53 QKVMSERFNDA----FQYGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYL 127
Cdd:PRK06348 45 ESIINAAFEDAkkghTRYTDSGGDVELIEEIIKYYSKNyDLSFKRNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFT 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 128 AALQVFQLAQANILSVDT-DDDGMLVEqlADLLE---TTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILED 203
Cdd:PRK06348 125 PYKDQIEMVGGKPIILETyEEDGFQIN--VKKLEaliTSKTKAI-ILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISD 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 204 DPYGEISFTDavrrPLYQHAVELSCEDQVVYTSTFSKILA-PGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQviTAE 282
Cdd:PRK06348 202 EVYDGFSFYE----DFVPMATLAGMPERTITFGSFSKDFAmTGWRIGYVIAPDYIIETAKIINEGICFSAPTISQ--RAA 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 283 YLSLNRLDNQIALIREDYRKKCVALADALESRlgEHLEFSRPQGGMFLWARFRYP-FDTMEWMKKTLENG-VVYVPGEAF 360
Cdd:PRK06348 276 IYALKHRDTIVPLIKEEFQKRLEYAYKRIESI--PNLSLHPPKGSIYAFINIKKTgLSSVEFCEKLLKEAhVLVIPGKAF 353
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
37-393 |
2.14e-19 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 89.14 E-value: 2.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 37 IPAPELFdTEGLELAVQKVMSerfndafqYGLTEGYPPLRQAVSEICHSRGVACSAAQVYITSGSQQSLDIVARTLLDPG 116
Cdd:PRK07568 42 IKTPEVF-FEAIKNYDEEVLA--------YSHSQGIPELREAFAKYYKKWGIDVEPDEILITNGGSEAILFAMMAICDPG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 117 DTIVVERPTYlAALQVF-QLAQANILSVDTD-DDGMLVEQLADLLE--TTRVKAvYLVPTFGNPGGKTLSEARRRRLVEL 192
Cdd:PRK07568 113 DEILVPEPFY-ANYNGFaTSAGVKIVPVTTKiEEGFHLPSKEEIEKliTPKTKA-ILISNPGNPTGVVYTKEELEMLAEI 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 193 AKKYDFVILEDDPYGEISFTDAVrrplYQHAVELS-CEDQVVYTSTFSK-ILAPGMRIGWIVM--PDWLAQqtvIVKQA- 267
Cdd:PRK07568 191 AKKHDLFLISDEVYREFVYDGLK----YTSALSLEgLEDRVIIIDSVSKrYSACGARIGCLISknKELIAA---AMKLCq 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 268 ADLHTNMLSQVITAEylSLNRLDNQIALIREDYRKKCVALADALESRLGEHleFSRPQGGMFLWARFryPFDTME----W 343
Cdd:PRK07568 264 ARLSPPTLEQIGAAA--LLDTPESYFDEVREEYKKRRDILYEELNKIPGVV--CEKPKGAFYIIAKL--PVDDAEdfakW 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 489006153 344 MKK--TLENGVVYV-PGEAFYHDkPDT--RTLRLSYSTVSEAgLLTAVERLAASL 393
Cdd:PRK07568 338 LLTdfNYNGETVMVaPASGFYAT-PGLgkNEIRIAYVLNEED-LKRAMEILKEAL 390
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
62-360 |
2.15e-19 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 89.00 E-value: 2.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 62 DAFQYGLTEGYPPLRQAVSEICHSR-GVAC-SAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQAN 139
Cdd:PRK08175 59 DTHGYSTSRGIPRLRRAISRWYQDRyDVDIdPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 140 ILSVDTDDDGMLVEQLADLLETTRVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRP 218
Cdd:PRK08175 139 VRSVPLVEGVDFFNELERAIRESYPKPKMMILGFpSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 219 LYQHAvelSCEDQVVYTSTFSKIL-APGMRIGWIV-MPDWLAQQTVIvKQAADLHTNMLSQVitAEYLSLNRLDNQIALI 296
Cdd:PRK08175 219 IMQVP---GAKDVAVEFFTLSKSYnMAGWRIGFMVgNPELVSALARI-KSYHDYGTFTPLQV--AAIAALEGDQQCVRDI 292
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489006153 297 REDYRKKCVALADALESrLGEHLEfsRPQGGMFLWARFRYPFDTM---EWMKKTLENGVVYV-PGEAF 360
Cdd:PRK08175 293 AEQYKRRRDVLVKGLHE-AGWMVE--MPKASMYVWAKIPEPYAAMgslEFAKKLLNEAKVCVsPGIGF 357
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
6-393 |
1.56e-18 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 86.15 E-value: 1.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 6 LAARAGELKPSAVRELLKHSK-LPGVISLGGG---IPAPELFDteglELAVQKVMS-ERFndafqYGLTEGYPPLRQAVS 80
Cdd:PRK06108 1 ARPAARALPESGIREVANAGRgREGVLPLWFGesdLPTPDFIR----DAAAAALADgETF-----YTHNLGIPELREALA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 81 EIcHSR--GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY--LAALQVFQLAQANILSVDTDDDGML--VEQ 154
Cdd:PRK06108 72 RY-VSRlhGVATPPERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWpnLVAAPKILGARVVCVPLDFGGGGWTldLDR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 155 LADLLeTTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRP-LYQHAVElscEDQVV 233
Cdd:PRK06108 151 LLAAI-TPRTRAL-FINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRAPsFLDIAEP---DDRII 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 234 YTSTFSK-ILAPGMRIGWIVMPDWLAQqtvIVKQAADLHTNMLSQ-VITAEYLSLNRLDNQIALIREDYRKKCVALADAL 311
Cdd:PRK06108 226 FVNSFSKnWAMTGWRLGWLVAPPALGQ---VLEKLIEYNTSCVAQfVQRAAVAALDEGEDFVAELVARLRRSRDHLVDAL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 312 ESRLGehLEFSRPQGGMFLWARFRYPFDTMEWMKKTL-ENGVVYVPGEAFyhdKPD-TRTLRLSYStVSEAGLLTAVERL 389
Cdd:PRK06108 303 RALPG--VEVAKPDGAMYAFFRIPGVTDSLALAKRLVdEAGLGLAPGTAF---GPGgEGFLRWCFA-RDPARLDEAVERL 376
|
....
gi 489006153 390 AASL 393
Cdd:PRK06108 377 RRFL 380
|
|
| hisC |
TIGR01141 |
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ... |
75-353 |
1.57e-18 |
|
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]
Pssm-ID: 273467 Cd Length: 350 Bit Score: 85.78 E-value: 1.57e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 75 LRQAVSEIChsrgvACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY----LAAlqvfQLAQANILSVDTDDDGM 150
Cdd:TIGR01141 60 LKQALADYY-----GVDPEQILLGNGSDEIIDLLIRAFLEPGDAVLVPPPTYsmyeISA----KIHGAEVVKVPLDEDGQ 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 151 LVEQLADLLETTRVKAVYLVpTFGNPGGKTLSEARRRRLVELAKKYDFVILeDDPYGEisFTDAVrrplyqHAVELSCE- 229
Cdd:TIGR01141 131 LDLEDILVAIDDKPKLVFLC-SPNNPTGNLFSRGDIEAVLERTPGDALVVV-DEAYGE--FSGEP------STLPLLAEy 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 230 DQVVYTSTFSKI--LApGMRIGWIVMPDWLAQQtvIVKQAADLHTNMLSQVITaeylslnrldnqIALIRE-DYRKKCVA 306
Cdd:TIGR01141 201 PNLIVLRTLSKAfgLA-GLRIGYAIANAEIIDA--LNKVRAPFNLSRLAQAAA------------IAALRDdDFIEATVE 265
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 489006153 307 LADA----LESRLGEHLEFS-RPQGGMFLWARFRYPFDtmEWMKKTLENGVV 353
Cdd:TIGR01141 266 EINAererLYDGLKKLPGLEvYPSDANFVLIRFPGDAD--ALFEALLEKGII 315
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
66-391 |
1.90e-18 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 86.17 E-value: 1.90e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAV-SEICHSRGVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY------LAALQVfqlaqa 138
Cdd:PRK07550 63 YGPVEGLPELREAYaAHYSRLYGAAISPEQVHITSGCNQAFWAAMVTLAGAGDEVILPLPWYfnhkmwLDMLGI------ 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 139 NILSVDTDD-DGML--VEQLADLLeTTRVKAVYLVpTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGeiSFTDAV 215
Cdd:PRK07550 137 RPVYLPCDEgPGLLpdPAAAEALI-TPRTRAIALV-TPNNPTGVVYPPELLHELYDLARRHGIALILDETYR--DFDSGG 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 216 RRPlyqHAV--ELSCEDQVVYTSTFSKILA-PGMRIGWIVM-PDWLAqqtvivkQAADLHTNM------LSQvITAEYlS 285
Cdd:PRK07550 213 GAP---HDLfaDPDWDDTLVHLYSFSKSYAlTGHRVGAVVAsPARIA-------EIEKFMDTVaicaprIGQ-IAVAW-G 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 286 LNRLDNQIALIREDYRKKCVALADALESRLGEHLEFSrpqGGMFLWARFRYPFDTMEWMKKTL--ENGVVYVPGEAFYHD 363
Cdd:PRK07550 281 LPNLADWRAGNRAEIARRRDAFRAVFARLPGWELLAS---GAYFAYVRHPFPDRPSREVARRLakEAGILCLPGTMFGPG 357
|
330 340
....*....|....*....|....*...
gi 489006153 364 kpDTRTLRLSYSTVSEAGLLTAVERLAA 391
Cdd:PRK07550 358 --QEGYLRLAFANADVAGIGELVERLRA 383
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
10-389 |
2.10e-18 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 85.94 E-value: 2.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 10 AGELKPSAVRELLK-HSKLPGVISLGGGipAPELFDTEGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSEICHSR-G 87
Cdd:PRK07682 1 VESLQPSGIRKFFDlAANMEGVISLGVG--EPDFVTPWNVREASIRSLEQGYT---SYTANAGLLELRQEIAKYLKKRfA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 88 VA-CSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLE--TTRV 164
Cdd:PRK07682 76 VSyDPNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPAQIEAaiTAKT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 165 KAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAvrrplYQHAVELS-CEDQVVYTSTFSKILA 243
Cdd:PRK07682 156 KAI-LLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDEA-----YTSFASIKgMRERTILISGFSKGFA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 244 -PGMRIGWIVMPDWLAQQTVIVKQAAdlhtnMLSQVITAEYLSLNRLDN---QIALIREDYRKKCVALADAL-ESRLGEH 318
Cdd:PRK07682 230 mTGWRLGFIAAPVYFSEAMLKIHQYS-----MMCAPTMAQFAALEALRAgndDVIRMRDSYRKRRNFFVTSFnEIGLTCH 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 319 LEfsrpqGGMFlwarfrYPFDTMEWMKKT---------LENGVVYVPGEAFyhDKPDTRTLRLSYSTVSEAgLLTAVERL 389
Cdd:PRK07682 305 VP-----GGAF------YAFPSISSTGLSseefaeqllLEEKVAVVPGSVF--GESGEGFIRCSYATSLEQ-LQEAMKRM 370
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
5-393 |
4.92e-18 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 84.73 E-value: 4.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 5 RLAARAGELKPSAVRELLKHSKL-----PGVISLGGGIP---APELFdTEGLELAVQKVMSerfndafQYGLTEGYPPLR 76
Cdd:PRK07337 2 RLAARVDAIEPFYVMELAKEAQAleragRDIIHMGIGEPdftAPEPV-VEAAARALRRGVT-------QYTSALGLAPLR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 77 QAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLA------------------ALQVFQLAQ 137
Cdd:PRK07337 74 EAIAAWYARRfGLDVAPERIVVTAGASAALLLACLALVERGDEVLMPDPSYPCnrhfvaaaegrpvlvpsgPAERFQLTA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 138 ANILSVDTDddgmlveqladllettRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRR 217
Cdd:PRK07337 154 ADVEAAWGE----------------RTRGV-LLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVS 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 218 PlyqhaveLSCEDQVVYTSTFSKILA-PGMRIGWIVMPDWLAqqTVIVKQAADLhtnMLSQVITAEYLSLNRLDNQIALI 296
Cdd:PRK07337 217 A-------LSLGDDVITINSFSKYFNmTGWRLGWLVVPEALV--GTFEKLAQNL---FICASALAQHAALACFEPDTLAI 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 297 ----REDYRKKCVALADALESrLGEHLEFsRPQGGMFLWARFRYPF-----DTMEWMKKTL-ENGVVYVPGEAFYHDKPD 366
Cdd:PRK07337 285 yerrRAEFKRRRDFIVPALES-LGFKVPV-MPDGAFYVYADCRGVAhpaagDSAALTQAMLhDAGVVLVPGRDFGPHAPR 362
|
410 420
....*....|....*....|....*..
gi 489006153 367 tRTLRLSYSTvSEAGLLTAVERLAASL 393
Cdd:PRK07337 363 -DYIRLSYAT-SMSRLEEAVARLGKLF 387
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
62-360 |
1.06e-17 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 83.96 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 62 DAFQYGLTEGYPPLRQAVSEICHSR-GVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQAN 139
Cdd:PRK09148 60 RTHRYSASKGIPGLRRAQAAYYARRfGVKLNPdTQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGGV 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 140 ILSVDTDDDGMLVEQLADLLETTRVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRP 218
Cdd:PRK09148 140 IRSVPAEPDEEFFPALERAVRHSIPKPIALIVNYpSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPS 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 219 LYQhaVELSCEDQVVYTS---TFSkilAPGMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVitAEYLSLNRLDNQIAL 295
Cdd:PRK09148 220 VLQ--VPGAKDVTVEFTSmskTFS---MAGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQV--AATAALNGPQDCIAE 292
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489006153 296 IREDYRKKCVALADALeSRLGehLEFSRPQGGMFLWARFRYPFD---TMEWMKKTLEN-GVVYVPGEAF 360
Cdd:PRK09148 293 MRELYKKRRDVLVESF-GRAG--WDIPPPAASMFAWAPIPEAFRhlgSLEFSKLLVEKaDVAVAPGVGF 358
|
|
| PRK15481 |
PRK15481 |
transcriptional regulatory protein PtsJ; Provisional |
31-393 |
2.74e-17 |
|
transcriptional regulatory protein PtsJ; Provisional
Pssm-ID: 185378 [Multi-domain] Cd Length: 431 Bit Score: 83.17 E-value: 2.74e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 31 ISLGGGIPAPELFdTEGLELAVQKVMSERFndafqYGLTEGYPPLRQAVSEIChsrGVACSAA-QVYITSGSqqsLDIVA 109
Cdd:PRK15481 88 HDLAGGNPDPQRL-PDLSRYFARLSRTPRL-----YGDAPVSPELHAWAARWL---RDDCPVAfEIDLTSGA---IDAIE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 110 RTL---LDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLETTrVKAVYLVPTFGNPGGKTLSEARR 186
Cdd:PRK15481 156 RLLcahLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDAEGMQPEKLERALAQG-ARAVILTPRAHNPTGCSLSARRA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 187 RRLVELAKKY-DFVILEDDPYGEISFTDavrrplYQHAVELSCEDQVVYTStFSKILAPGMRIGWIvmpdwlaqqtvivk 265
Cdd:PRK15481 235 AALRNLLARYpQVLVIIDDHFALLSSSP------YHSVIPQTTQRWALIRS-VSKALGPDLRLAFV-------------- 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 266 qAADLHTNM---------------LSQVITAEYLSLNRLDNQIALIREDYRKKCVALADALESrlgEHLEFSRPQGGMFL 330
Cdd:PRK15481 294 -ASDSATSArlrlrlnsgtqwvshLLQDLVYACLTDPEYQARLAQARLFYAQRRQKLARALQQ---YGIAIPSPGDGLNL 369
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489006153 331 WARFryPFDTMEWMKKTLENGVVYVPGEAFYHDKPdTRTLRLSYSTVSEagllTAVERLAASL 393
Cdd:PRK15481 370 WLPL--DTDSQATALTLAKSGWLVREGEAFGVSAP-SHGLRITLSTLND----AEINRLAADL 425
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
29-391 |
2.75e-17 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 82.66 E-value: 2.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 29 GVISLGGGIP----APELFDteglelAVQKVMSERFNdafQYGLTEGYPPLRQAVSE-ICHSRGVACSAA-QVYITSGSQ 102
Cdd:PRK09082 31 GAINLSQGFPdfdgPPYLVE------ALAYAMAAGHN---QYPPMTGVAALREAIAAkTARLYGRQYDADsEITVTAGAT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 103 QSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLV--EQLADLLeTTRVKAVyLVPTFGNPGGKT 180
Cdd:PRK09082 102 EALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQPPDFRVdwQRFAAAI-SPRTRLI-ILNTPHNPSGTV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 181 LSEARRRRLVELAKKYDFVILEDDPYGEISF-----TDAVRRP-LYQHAVelscedqVVytSTFSKIL-APGMRIGWIVM 253
Cdd:PRK09082 180 WSAADMRALWQLIAGTDIYVLSDEVYEHIVFdgaghASVLRHPeLRERAF-------VV--SSFGKTYhVTGWKVGYCVA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 254 PDWLAQQTVIVKQAADLHTNMLSQVITAEYLslnrldnqialiRED----------YRKKCVALADALE-SRLgehlEFS 322
Cdd:PRK09082 251 PAALSAEFRKVHQYNTFTVNTPAQLALADYL------------RAEpehylelpafYQAKRDRFRAALAnSRF----KLL 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489006153 323 RPQGGMFLWARFRYPFDTME-----WMkkTLENGVVYVPGEAFYHDKPDTRTLRLSYSTvSEAGLLTAVERLAA 391
Cdd:PRK09082 315 PCEGTYFQLVDYSAISDLDDvefcqWL--TREHGVAAIPLSVFYADPFPHRLVRLCFAK-QEETLDAAAERLCQ 385
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
29-391 |
2.82e-17 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 82.78 E-value: 2.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 29 GVISLGGGIPapelfDTEG----LELAVQKVMSERfNdafQYGLTEGYPPLRQAVSEICHSR-GVACSA-AQVYITSGSQ 102
Cdd:PRK07777 25 GAVNLGQGFP-----DEDGppemLEAAQEAIAGGV-N---QYPPGPGIPELRAAIAAQRRRRyGLEYDPdTEVLVTVGAT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 103 QSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDG----MLVEQLADLLeTTRVKAVyLVPTFGNPGG 178
Cdd:PRK07777 96 EAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVPDGrgfaLDLDALRAAV-TPRTRAL-IVNSPHNPTG 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 179 KTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLyqhAVELSCEDQVVYTSTFSKILA-PGMRIGWIVMPDWL 257
Cdd:PRK07777 174 TVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPL---ATLPGMRERTVTISSAAKTFNvTGWKIGWACGPAPL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 258 AQQTVIVKQAADLHTNMLSQVITAEYLSLNrlDNQIALIREDYRKKCVALADALeSRLGehLEFSRPQGGMFLWARFRyP 337
Cdd:PRK07777 251 IAAVRAAKQYLTYVGGAPFQPAVAHALDHE--DAWVAALRDSLQAKRDRLAAGL-AEAG--FEVHDSAGTYFLCADPR-P 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 489006153 338 F---DTMEWMKKTLEN-GVVYVPGEAFYHDKPDTRTL-RLSYSTVSEAgLLTAVERLAA 391
Cdd:PRK07777 325 LgydDGTEFCRALPERvGVAAIPMSVFYDPADAWNHLvRFAFCKRDDT-LDEAIRRLRA 382
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
24-389 |
2.89e-17 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 82.53 E-value: 2.89e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 24 HSKLPGV-----------------ISLGGGipAPELFDTEGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSE-ICHS 85
Cdd:PRK12414 8 RSKLPDVgttiftvigqlaaqhdaLNLSQG--APNFAPDPALVEGVARAMRDGHN---QYAPMAGIAALREALAEkTERL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 86 RGVACSAA-QVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLV---EQLADLLET 161
Cdd:PRK12414 83 YGARYDPAsEVTVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEDFRVnwdEVAAAITPR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 162 TRVkavYLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAvELSceDQVVYTSTFSKI 241
Cdd:PRK12414 163 TRM---IIVNTPHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHR-ELA--ERSVIVSSFGKS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 242 L-APGMRIGWIVMPDWLAQQTVIVKQ----AADlhTNMlsQVITAEYLSlnRLDNQIALiREDYRKKCVALADALEsrlG 316
Cdd:PRK12414 237 YhVTGWRVGYCLAPAELMDEIRKVHQfmvfSAD--TPM--QHAFAEALA--EPASYLGL-GAFYQRKRDLLARELA---G 306
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489006153 317 EHLEFSRPQGGMFLWARFRYPFDTM--EWMKKTL-ENGVVYVPGEAFYHDKPDTRTLRLSYSTvSEAGLLTAVERL 389
Cdd:PRK12414 307 SRFELLPSEGSFFMLARFRHFSDESdsDFVLRLIrDARVATIPLSAFYTDGTDTGLIRLSFSK-DDATLVEGARRL 381
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
30-255 |
3.82e-17 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 82.28 E-value: 3.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 30 VISLGGGIP-APELFDTE--GLELAVQKVMSERFNDafqYGLTEGYPPLRQAVSEIChSRGV--ACSAAQVYITSGSQQS 104
Cdd:PLN02656 33 VISLGMGDPtAYSCFHTThvAQEAVVDALQSNKFNG---YAPTVGLPQARRAIAEYL-SRDLpyKLSLDDVFITSGCTQA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 105 LDIVARTLLDPGDTIVVERPTY----LAA----LQV--FQLAQANILSVDTDddgmLVEQLADllETTrVKAVYLVPtfG 174
Cdd:PLN02656 109 IDVALSMLARPGANILLPRPGFpiyeLCAafrhLEVryVDLLPEKGWEVDLD----AVEALAD--QNT-VALVIINP--G 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 175 NPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTdavRRPLYQHAVELSCEDQVVYTSTFSKILAPGMRIGWIVMP 254
Cdd:PLN02656 180 NPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFG---SNPFVPMGVFGSIVPVLTLGSLSKRWIVPGWRLGWFVTT 256
|
.
gi 489006153 255 D 255
Cdd:PLN02656 257 D 257
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
66-360 |
5.84e-17 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 81.67 E-value: 5.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAVSEICHSR-GVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANI--- 140
Cdd:PRK08636 67 YSVSKGIYKLRLAICNWYKRKyNVDLDPeTEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYPIHSQAFILAGGNVhkm 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 141 -LSVDTD---DDGMLVEQLADLLETTRVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAV 215
Cdd:PRK08636 147 pLEYNEDfelDEDQFFENLEKALRESSPKPKYVVVNFpHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYK 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 216 RRPLYQhaVElSCEDQVVYTSTFSKI--LApGMRIGWIVMPDWLAQQTVIVKQAADLhtNMLSQVITAEYLSLNRLDNQI 293
Cdd:PRK08636 227 TPSILE--VE-GAKDVAVESYTLSKSynMA-GWRVGFVVGNKKLVGALKKIKSWLDY--GMFTPIQVAATIALDGDQSCV 300
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489006153 294 ALIREDYRKKCVALADALEsRLGEHLEfsRPQGGMFLWARFRYPF---DTMEWMKKTLENGVVYV-PGEAF 360
Cdd:PRK08636 301 EEIRETYRKRRDVLIESFA-NAGWELQ--KPRASMFVWAKIPEPArhlGSLEFSKQLLTEAKVAVsPGIGF 368
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
17-393 |
1.12e-16 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 80.89 E-value: 1.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 17 AVRELLKHSklPGVISLGGGI----PAPElfdteglelaVQKVMSERFND--AFQYGLTEGYPPLRQAVSE-ICHSRGVA 89
Cdd:PRK05957 18 VVGQLIREN--PGTISLGQGVvsypPPPE----------AIEALNNFLANpeNHKYQAVQGIPPLLEAITQkLQQDNGIE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 90 CSAAQ-VYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLveQLaDLLE---TTRVK 165
Cdd:PRK05957 86 LNNEQaIVVTAGSNMAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDDNYQL--QP-EAIEqaiTPKTR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 166 AVYLV-PTfgNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAvrrplyQHAVELSCEDQVVYT-STFSKILA 243
Cdd:PRK05957 163 AIVTIsPN--NPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGV------KHFSPGSIPGSGNHTiSLYSLSKA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 244 PGM---RIGWIVMPDWLaqqTVIVKQAADlhTNMLSQVITAEYLSLNRLdnqiaLIREDYRKKCVA--------LADALe 312
Cdd:PRK05957 235 YGFaswRIGYMVIPIHL---LEAIKKIQD--TILICPPVVSQYAALGAL-----QVGKSYCQQHLPeiaqvrqiLLKSL- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 313 SRLGEHLEFSRPQGGMFLWARFRYPFDTMEWMKKTLEN-GVVYVPGEAFYHDKpdTRTLRLSYSTVSEAGLLTAVERLAA 391
Cdd:PRK05957 304 GQLQDRCTLHPANGAFYCFLKVNTDLNDFELVKQLIREyRVAVIPGTTFGMKN--GCYLRIAYGALQKATAKEGIERLVQ 381
|
..
gi 489006153 392 SL 393
Cdd:PRK05957 382 GL 383
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
5-391 |
8.56e-16 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 78.29 E-value: 8.56e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 5 RLAARAGELKPSAVRELLKHSKlpGVISLGGGIPAPElfdtEGLELAVQKVMSERFNDafqYGLTEGYPPLRQAVSEICH 84
Cdd:TIGR01264 17 RAIVDNMKVKPNPEKPMIKLSI--GDPTVFGNLPTDP----EVMQAMKDSLDSGKYNG---YAPTVGALSAREAIASYYH 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 85 SRGVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY-----LAALQVFQLAQANIL---SVDTDDDGMlvEQLA 156
Cdd:TIGR01264 88 NPDGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPGFplyetLAESMGIEVKLYNLLpdkSWEIDLKQL--ESLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 157 DllETTrvkAVYLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLyqhaVELSCEDQVVYTS 236
Cdd:TIGR01264 166 D--EKT---AALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPL----ASLSSTVPILSCG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 237 TFSK-ILAPGMRIGWIVMPDW-------------LAQQTV----IVKQAadlhtnmLSQVIT---AEYlslnrLDNQIAL 295
Cdd:TIGR01264 237 GLAKrWLVPGWRLGWIIIHDRrgilrdirdglvkLSQRILgpctIVQGA-------LPSILLrtpQEY-----FDGTLSV 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 296 IREDyrkkcvalADALESRLGE--HLEFSRPQGGMFLWA-----RFRYPFDTMEWMKKTLENGVVYV-PGEAFyhDKPDT 367
Cdd:TIGR01264 305 LESN--------AMLCYGALAAvpGLRPVMPSGAMYMMVgiemeHFPEFKNDVEFTERLVAEQSVFClPGSCF--EYPGF 374
|
410 420
....*....|....*....|....
gi 489006153 368 RTLRLsysTVSEAGLLTAVERLAA 391
Cdd:TIGR01264 375 FRVVL---TVPVVMMEEACSRIQE 395
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
56-360 |
2.26e-15 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 77.16 E-value: 2.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 56 MSERFNDAFQ-----YGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAA 129
Cdd:PRK08363 51 MKEAYCRAIKeghnyYGPSEGLPELREAIVKREKRKnGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYPPY 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 130 LQVFQLAQANILSVDTDDDGMLVEQLADLLE--TTRVKAVYLV-PTfgNPGGKTLSEARRRRLVELAKKYDFVILEDDPY 206
Cdd:PRK08363 131 TGLVKFYGGVPVEYRTIEEEGWQPDIDDIRKkiTEKTKAIAVInPN--NPTGALYEKKTLKEILDIAGEHDLPVISDEIY 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 207 GEISFTDAVRRPlyqhaVELSCEDQVVYTSTFSKI-LAPGMRIGWIVMPDwLAQQTVIVKQAAD-LHTNMLSQVITAEYL 284
Cdd:PRK08363 209 DLMTYEGKHVSP-----GSLTKDVPVIVMNGLSKVyFATGWRLGYIYFVD-PEGKLAEVREAIDkLARIRLCPNTPAQFA 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 285 SLNRLDNQIALIrEDYRKKCVALADALESRLGE--HLEFSRPQGGMFLWARFR-YPF-DTMEWMKKTLEN-GVVYVPGEA 359
Cdd:PRK08363 283 AIAGLTGPMDYL-EEYMKKLKERRDYIYKRLNEipGISTTKPQGAFYIFPRIEeGPWkDDKEFVLDVLHEaHVLFVHGSG 361
|
.
gi 489006153 360 F 360
Cdd:PRK08363 362 F 362
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
72-352 |
3.77e-15 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 75.94 E-value: 3.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 72 YPPLRQAVSEICHsrgvaCSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGML 151
Cdd:COG0079 50 ATALREALAEYYG-----VPPEQVLVGNGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLDEDFSL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 152 -VEQLADLLeTTRVKAVYLV-PTfgNPGGKTLSEARRRRLVELAKKYDFVIL-EddpygeiSFTDAVRRPlyQHAVEL-S 227
Cdd:COG0079 125 dLDALLAAI-TERTDLVFLCnPN--NPTGTLLPREELEALLEALPADGLVVVdE-------AYAEFVPEE--DSALPLlA 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 228 CEDQVVYTSTFSKILA-PGMRIGWIVMPDWLAQQTVIVKQAadLHTNMLSQVITAEYLS-LNRLDNQIALIREDyRKKcv 305
Cdd:COG0079 193 RYPNLVVLRTFSKAYGlAGLRLGYAIASPELIAALRRVRGP--WNVNSLAQAAALAALEdRAYLEETRARLRAE-RER-- 267
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 489006153 306 aLADALEsRLGehLEFSRPQGGmFLWARFryPFDTMEWMKKTLENGV 352
Cdd:COG0079 268 -LAAALR-ALG--LTVYPSQAN-FVLVRV--PEDAAELFEALLERGI 307
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
31-255 |
8.70e-15 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 75.43 E-value: 8.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 31 ISLGGGIPAP-ELFDTEGL--ELAVQKVMSERFNdafQYGLTEGYPPLRQAVSE-ICHSRGVACSAAQVYITSGSQQSLD 106
Cdd:PLN00143 35 ISFGFGDPSCfECFRTTNIaeDAIVEAVRSAKFN---SYAPTGGILPARRAIADyLSNDLPYQLSPDDVYLTLGCKHAAE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 107 IVARTLLDPGDTIVVERPTY-----LAALQVFQLAQANIL-----SVDTDddgmLVEQLADllETTrVKAVYLVPtfGNP 176
Cdd:PLN00143 112 IIIKVLARPEANILLPRPGFpdvetYAIFHHLEIRHFDLLpekgwEVDLD----AVEAIAD--ENT-IAMVIINP--GNP 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489006153 177 GGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDavrRPLYQHAVELSCEDQVVYTSTFSKILAPGMRIGWIVMPD 255
Cdd:PLN00143 183 CGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGS---KPFVPMGLFASIVPVITLGSISKRWMIPGWGLGWLVTCD 258
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
5-393 |
1.56e-14 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 74.52 E-value: 1.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 5 RLAARAGELKPSAVREL----LKHsklpGVISLGGGIP---APELFDteglELAVQKVMSERfNdafQYGLTEGYPPLRQ 77
Cdd:PLN00175 31 QVAKRLEKFKTTIFTQMsslaIKH----GAINLGQGFPnfdGPDFVK----EAAIQAIRDGK-N---QYARGFGVPELNS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 78 AVSE-ICHSRGVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANI--LSVDTDDDGMLVE 153
Cdd:PLN00175 99 AIAErFKKDTGLVVDPeKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIktVTLRPPDFAVPED 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 154 QLADLLeTTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISF-----TDAVRRPLYQHAVELSC 228
Cdd:PLN00175 179 ELKAAF-TSKTRAI-LINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFegdhiSMASLPGMYERTVTMNS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 229 EDQvvytsTFSkilAPGMRIGWIVMPDWLaqqTVIVKQAadlHTNMLSQVIT----AEYLSLNRLDNQIALIREDYRKKC 304
Cdd:PLN00175 257 LGK-----TFS---LTGWKIGWAIAPPHL---TWGVRQA---HSFLTFATATpmqwAAVAALRAPESYYEELKRDYSAKK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 305 VALADALESrLGehLEFSRPQGGMFLWARfRYPF---DTMEWMKKTLEN-GVVYVPGEAFYHDKPDTRTL-RLSYSTvSE 379
Cdd:PLN00175 323 DILVEGLKE-VG--FKVYPSSGTYFVMVD-HTPFgfeNDIAFCEYLIEEvGVAAIPPSVFYLNPEDGKNLvRFAFCK-DE 397
|
410
....*....|....
gi 489006153 380 AGLLTAVERLAASL 393
Cdd:PLN00175 398 ETLRAAVERMKTKL 411
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
19-333 |
2.04e-14 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 74.14 E-value: 2.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 19 RELLKHSKLPGV---ISLGGGIP---APELfdteglelaVQKVMSERFNDAFQYGLTEGYPPLRQAVSEICHSR-GVAC- 90
Cdd:PRK09147 17 RALFAGVTPPADlppISLSIGEPkhpTPAF---------IKDALAANLDGLASYPTTAGLPALREAIAAWLERRyGLPAl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 91 -SAAQVYITSGSQQSLDIVARTLLDPGD---TIVVERPTYL----AALqvfqLAQANILSVDTDDDGMLVEQLADLLETT 162
Cdd:PRK09147 88 dPATQVLPVNGSREALFAFAQTVIDRDGpgpLVVCPNPFYQiyegAAL----LAGAEPYFLNCDPANNFAPDFDAVPAEV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 163 --RVKAVYlVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFtDAVRRPL--YQHAVEL---SCEDQVVYT 235
Cdd:PRK09147 164 waRTQLLF-VCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECYSEIYF-DEAAPPLglLEAAAELgrdDFKRLVVFH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 236 STFSKILAPGMRIGWIvmpdwlAQQTVIVKQAADLHT----NMLSQVITAEYLSLNR----LDNqialiREDYRKKcval 307
Cdd:PRK09147 242 SLSKRSNVPGLRSGFV------AGDAALLKKFLLYRTyhgcAMPPAVQAASIAAWNDeahvREN-----RALYREK---- 306
|
330 340
....*....|....*....|....*.
gi 489006153 308 ADALESRLGEHLEFSRPQGGMFLWAR 333
Cdd:PRK09147 307 FDAVTPILAPVLDVQLPDAGFYLWAK 332
|
|
| Asp_aminotransf |
pfam12897 |
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group ... |
36-391 |
8.76e-14 |
|
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of amino-transferases acts as dimers in a head-to-tail configuration. It has been demonstrated that these proteins are aspartate amino-transferases from Bacteria (Jansen, R.S. et al. Nat Commun 11, 1960 (2020)).
Pssm-ID: 403948 Cd Length: 419 Bit Score: 72.20 E-value: 8.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 36 GIPAPELFDTEGLELAVQKVMSERFNDAF---QYGLTEGYPPLRQAVSEIchsrgVACSAAQVYITSGSQQSL--DIVAR 110
Cdd:pfam12897 31 GKPADAQLDLSNGLLALPGAGDYRAADGTdtrNYGGLAGLPEARAIFAEY-----LDVPTENVLVWNNSSLELmhLVLTF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 111 TLL------------DPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLL-ETTRVKAVYLVPTFGNPG 177
Cdd:pfam12897 106 ALLhgvrdgegpwvaQETVKFLCPVPGYDRHFAILETLGIEMITVDLQDDGPDMDAVERLVaKDPSIKGIWFVPKYSNPT 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 178 GKTLSEARRRRLVEL-AKKYDFVILEDDPYG-EISFTDAVRRPlyqHAVELsCEDQ------VVYTSTfSKILAPGMRIG 249
Cdd:pfam12897 186 GETISEEVARRLAGMkTAAPDFRIFWDNAYAvHHLVGEGDRDP---NIVGL-ARDAghpnrpFVFAST-SKITFAGAGVG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 250 WIVM-PD---WLAQQTVIVKQAADlHTNMLSQV-ITAEYLSLNRL-DNQIALIREDYRkkcvALADALESRLG--EHLEF 321
Cdd:pfam12897 261 FVASsEDniaWLGKYLGAQSIGPD-KVNQLRHVrFLGDYEGLEGHmRRHAALIAPKFA----AVLEILEAELGggGYATW 335
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489006153 322 SRPQGGMFLwarfryPFDTMEWMKKTL-----ENGVVYVPGEAFY--HDKPDTRTLRLSYSTVSEAGLLTAVERLAA 391
Cdd:pfam12897 336 TEPRGGYFI------SLDTLDGVAKRVvalakEAGVSLTPAGATYphGEDPHDRNIRLAPTRPPLEEVRTAMDVVAT 406
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
71-393 |
1.18e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 71.62 E-value: 1.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 71 GYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQL--AQANILSVDTDD 147
Cdd:PRK08960 70 GLPALREAIAGFYAQRyGVDVDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLveGAAQLVPVGPDS 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 148 DGMLVEQLADLLETTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISF-TDAvrrplyqhAVEL 226
Cdd:PRK08960 150 RYQLTPALVERHWNADTVGA-LVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYgVDA--------ASVL 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 227 SCEDQVVYTSTFSKILA-PGMRIGWIVMPDWLAQQtvIVKQAADLHtnmLSQVITAEYLSLNRLDNQIALI----REDYR 301
Cdd:PRK08960 221 EVDDDAFVLNSFSKYFGmTGWRLGWLVAPPAAVPE--LEKLAQNLY---ISASTPAQHAALACFEPETLAIlearRAEFA 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 302 KKCVALADALESrLGEHLEfSRPQGGMFLWARF-RYPFDTMEWMKKTLEN-GVVYVPGEAFYHDKPDtRTLRLSYSTvSE 379
Cdd:PRK08960 296 RRRDFLLPALRE-LGFGIA-VEPQGAFYLYADIsAFGGDAFAFCRHFLETeHVAFTPGLDFGRHQAG-QHVRFAYTQ-SL 371
|
330
....*....|....
gi 489006153 380 AGLLTAVERLAASL 393
Cdd:PRK08960 372 PRLQEAVERIARGL 385
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
41-382 |
1.42e-13 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 71.51 E-value: 1.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 41 ELFDTEGLElaVQKVMSERFNDAFQYGLTEGYPPLRQAVSEICHSRgvacSAAQVYITSGSQQSLDIVARTLLDPGDTIV 120
Cdd:PRK07324 35 ELLALAGKN--PEAFYQELGQKKLTYGWIEGSPEFKEAVASLYQNV----KPENILQTNGATGANFLVLYALVEPGDHVI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 121 VERPTYlaalQvfQL--------AQANILSVDtDDDGML--VEQLADLL-ETTRVKAvylVPTFGNPGGKTLSEARRRRL 189
Cdd:PRK07324 109 SVYPTY----Q--QLydipeslgAEVDYWQLK-EENGWLpdLDELRRLVrPNTKLIC---INNANNPTGALMDRAYLEEI 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 190 VELAKKYDFVILEDDPYgeisftdavrRPLYQHAVELSCEDqvVY-----TSTFSKILA-PGMRIGWIVMPDWLAQqtvI 263
Cdd:PRK07324 179 VEIARSVDAYVLSDEVY----------RPLDEDGSTPSIAD--LYekgisTNSMSKTYSlPGIRVGWIAANEEVID---I 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 264 VKQAADLhtNMLSQVITAEYLSLNRLDNQIALI---REDYRKKCVALADALESRlgEHLEFSRPQGGMFLWARFRYPFDT 340
Cdd:PRK07324 244 LRKYRDY--TMICAGVFDDMLASLALEHRDAILernRKIVRTNLAILDEWVAKE--PRVSYVKPKAVSTSFVKLDVDMPS 319
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489006153 341 MEWMKKTLEN-GVVYVPGEAFyhDKPDtrTLRLSY---STVSEAGL 382
Cdd:PRK07324 320 EDFCLKLLKEtGVLLVPGNRF--DLEG--HVRIGYccdTETLKKGL 361
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
30-255 |
5.51e-13 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 69.80 E-value: 5.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 30 VISLGGGIPAP-ELFDT--EGLELAVQKVMSERFNdafQYGLTEGYPPLRQAVSEIChSRGV--ACSAAQVYITSGSQQS 104
Cdd:PLN00145 54 VLPLGHGDPSAfPCFRTapEAEDAVAAALRSGKYN---SYSTCVGLLPARRAIAEYL-SRDLpyELSTDDIYLTAGCAQA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 105 LDIVARTLLDPGDTIVVERPTYL-----AALQVFQLAQANIL-----SVDTDDdgmlVEQLADllETTrVKAVYLVPtfG 174
Cdd:PLN00145 130 IEIIMSVLAQPGANILLPRPGYPlyearAVFSGLEVRHFDLLpergwEVDLEG----VEALAD--ENT-VAMVIINP--N 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 175 NPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDavrRPLYQHAVELSCEDQVVYTSTFSKILAPGMRIGWIVMP 254
Cdd:PLN00145 201 NPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGS---KPFVPMGVFGEVAPVLTLGSISKRWVVPGWRLGWIATC 277
|
.
gi 489006153 255 D 255
Cdd:PLN00145 278 D 278
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
8-360 |
1.38e-12 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 68.59 E-value: 1.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 8 ARAGELKPSAVRELLKhsklpgVISLGGGIP---APElfdtEGLELAVQkvmserfndAFQYGLTEGYPPL------RQA 78
Cdd:PRK05942 21 ARLDELKARAREQGLD------LIDLGMGNPdgaAPQ----PVIEAAIA---------ALADPQNHGYPPFegtasfRQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 79 VSEICHSR-GVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANI----LSVDTD---DDG 149
Cdd:PRK05942 82 ITDWYHRRyGVELDPdSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHFRGPLIAGAQIypiiLKPENDwliDLS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 150 MLVEQLADllettRVKAVYlvptFGNPGGKTLSEARR---RRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQ--HAV 224
Cdd:PRK05942 162 SIPEEVAQ-----QAKILY----FNYPSNPTTATAPReffEEIVAFARKYEIMLVHDLCYAELAFDGYQPTSLLEipGAK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 225 ELSCEdqvvyTSTFSKIL-APGMRIGWIVmpdwlaQQTVIVKQAADLHTNM----LSQVITAEYLSLNRLDNQIALIRED 299
Cdd:PRK05942 233 DIGVE-----FHTLSKTYnMAGWRVGFVV------GNRHIIQGLRTLKTNLdygiFSALQKAAETALQLPDSYLQQVQER 301
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489006153 300 YRKKCVALADALeSRLGEHLEfsRPQGGMFLWARFRYPFDTMEWMKKTLEN-GVVYVPGEAF 360
Cdd:PRK05942 302 YRTRRDFLIQGL-GELGWNIP--PTKATMYLWVPCPVGMGSTDFALNVLQKtGVVVTPGNAF 360
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
29-391 |
1.34e-11 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 65.38 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 29 GVISLGGGIPapelfDTEGLELAVQKVMSERFNDAFQYGLTEGYPPLRQAVSEicHSR---GVACS-AAQVYITSGSQQS 104
Cdd:PRK08912 27 GAINLGQGFP-----DDPGPEDVRRAAADALLDGSNQYPPMMGLPELRQAVAA--HYArfqGLDLDpETEVMVTSGATEA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 105 LDIVARTLLDPGDTIVVERPTYLAALQVFQLAQA--NILSVDTDDDGMLVEQLADLLeTTRVKAVyLVPTFGNPGGKTLS 182
Cdd:PRK08912 100 LAAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGvpRLVRLEPPHWRLPRAALAAAF-SPRTKAV-LLNNPLNPAGKVFP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 183 EARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYqhAVElSCEDQVVYTSTFSKILA-PGMRIGWIVMPDWLAQQT 261
Cdd:PRK08912 178 REELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLM--TLP-GMRERTVKIGSAGKIFSlTGWKVGFVCAAPPLLRVL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 262 VIVKQAADLHTNMLSQVITAEylSLNRLDNQIALIREDYRKKCVALADALEsRLGehLEFSRPQGGMFLWARFR---YPF 338
Cdd:PRK08912 255 AKAHQFLTFTTPPNLQAAVAY--GLGKPDDYFEGMRADLARSRDRLAAGLR-RIG--FPVLPSQGTYFLTVDLAplgLAE 329
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 489006153 339 DTMEWMKK-TLENGVVYVPGEAFYHDKPDTRTLRLSYSTvSEAGLLTAVERLAA 391
Cdd:PRK08912 330 DDVAFCRRlVEEAGVAAIPVSAFYEEDPVTSVVRFCFAK-RDATLDEAVERLAA 382
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
8-277 |
2.15e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 64.77 E-value: 2.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 8 ARAGELKPSAV----RELLKHSKLPGVISLGGGipAPELFDTEGLELAVQKVMSER-FNdafQYGLTEGYPPLRQAVSEI 82
Cdd:PRK06225 4 AKAAKVPPSGFktsnEFFDYVFKDKEMIWMGQN--TNHLGPHEEVREAMIRCIEEGeYC---KYPPPEGFPELRELILKD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 83 CHSRGvacsaAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLaALQVFQLAQAN-ILSVDTDDDG----MLVEQL-A 156
Cdd:PRK06225 79 LGLDD-----DEALITAGATESLYLVMRAFLSPGDNAVTPDPGYL-IIDNFASRFGAeVIEVPIYSEEcnykLTPELVkE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 157 DLLETTRVkaVYLV-PTfgNPGGKTLSEARRRRLVELAKKYDFVILEDdpygeISFTDAVRRplyQHAVELSCEDQVVYT 235
Cdd:PRK06225 153 NMDENTRL--IYLIdPL--NPLGSSYTEEEIKEFAEIARDNDAFLLHD-----CTYRDFARE---HTLAAEYAPEHTVTS 220
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 489006153 236 STFSKILA-PGMRIGWIV-MPDWLAQQTVIVkqAADLHTNMLSQ 277
Cdd:PRK06225 221 YSFSKIFGmAGLRIGAVVaTPDLIEVVKSIV--INDLGTNVIAQ 262
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
12-360 |
1.90e-10 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 62.11 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 12 ELKPS-AVRELLKHSKlpGVISLGGGIPAPELFdTEGLelaVQKVMSERFNDAFQyglTEGYPPLRQAVSE-----ICH- 84
Cdd:PTZ00433 25 NAKPSpSPKSIIKLSV--GDPTLDGNLLTPAIQ-TKAL---VEAVDSQECNGYPP---TVGSPEAREAVATywrnsFVHk 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 85 -SRGVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERP----------TYLAALQVFQLAQANILSVDTDDDGMLVE 153
Cdd:PTZ00433 96 eSLKSTIKKDNVVLCSGVSHAILMALTALCDEGDNILVPAPgfphyetvckAYGIEMRFYNCRPEKDWEADLDEIRRLVD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 154 qladlletTRVKAVyLVPTFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAVELScedQVV 233
Cdd:PTZ00433 176 --------DRTKAL-IMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVP---RVI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 234 YTSTFSKILAPGMRIGWIVM-------PDWLaqqtVIVKQAADL--HTNMLSQVITAEYLsLNRLDNQIALIREDYRKKC 304
Cdd:PTZ00433 244 LGGTAKNLVVPGWRLGWLLLvdphgngGDFL----DGMKRLGMLvcGPCSVVQAALGEAL-LNTPQEHLEQIVAKLEEGA 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489006153 305 VALADALESRLGehLEFSRPQGGMFLWAR-----FRYPFDTMEWMKKTLENGVVYV-PGEAF 360
Cdd:PTZ00433 319 MVLYNHIGECIG--LSPTMPRGSMFLMSRldlekFRDIKSDVEFYEKLLEEENVQVlPGEIF 378
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
66-362 |
7.59e-09 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 57.28 E-value: 7.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAVSE-ICHSRGVACSAAQVYITSGSQQSLDIVARTLL-DPGDTIVVERPTY-LAALQVFQLA--QANI 140
Cdd:PTZ00377 111 YTDSAGYPFVRKAVAAfIERRDGVPKDPSDIFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYpLYSAAITLLGgkQVPY 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 141 LSVDTDDDGMLVEQLADLLETTR-----VKAVYLV-PtfGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGE------ 208
Cdd:PTZ00377 191 YLDEEKGWSLDQEELEEAYEQAVrngitPRALVVInP--GNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQEniydge 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 209 ---ISFTDAVR--RPLYQHAVELscedqVVYTSTFSKILAP-GMRIGWIVM----PDWLAQqtvIVKQAA-DLHTNMLSQ 277
Cdd:PTZ00377 269 kpfISFRKVLLelPAEYNTDVEL-----VSFHSTSKGIIGEcGRRGGYFELtnipPEVREQ---IYKLASiNLCSNVVGQ 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 278 VITAEYLSLNRLDNQIAlirEDYRKKCVALADALESRLG---------EHLEFSRPQGGMFLWARFRYP----------- 337
Cdd:PTZ00377 341 LMTGLMCNPPREGDASY---PLYKRERDAIFTSLKRRAElltdelnkiEGVSCQPVEGAMYAFPRIELPekaiqeakerg 417
|
330 340 350
....*....|....*....|....*....|....
gi 489006153 338 --FDTMeWMKKTLEN-GVVYVPGEAF------YH 362
Cdd:PTZ00377 418 laPDVL-YCLELLEStGIVVVPGSGFgqkpgtYH 450
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
72-353 |
2.75e-08 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 55.09 E-value: 2.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 72 YP-----PLRQAVSEIChsrgvACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYlaALQVFQLAQANILSVD-- 144
Cdd:PLN03026 83 YPdpesrRLRAALAEDS-----GLESENILVGCGADELIDLLMRCVLDPGDKIIDCPPTF--GMYVFDAAVNGAEVIKvp 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 145 -TDDDGMLVEQLADLLETTRVKAVYLV-PtfGNPGGKTLSEARRRRLVELAKkydFVILeDDPYGEISFTDAVRRPLYQH 222
Cdd:PLN03026 156 rTPDFSLDVPRIVEAVETHKPKLLFLTsP--NNPDGSIISDDDLLKILELPI---LVVL-DEAYIEFSTQESRMKWVKKY 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 223 avelsceDQVVYTSTFSKILA-PGMRIGWIVMPDWLAQQTVIVKQAADLHtnmlsqvITAEYLSLNRLDNQIALirEDYR 301
Cdd:PLN03026 230 -------DNLIVLRTFSKRAGlAGLRVGYGAFPLSIIEYLWRAKQPYNVS-------VAAEVAACAALSNPKYL--EDVK 293
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 489006153 302 KKCVALADALESRLGEhLEFSR--PQGGMFLWARFRYPFDTMEWMKKTLENGVV 353
Cdd:PLN03026 294 NALVEERERLFGLLKE-VPFLEpyPSDANFILCRVTSGRDAKKLKEDLAKMGVM 346
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
94-253 |
9.70e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 51.23 E-value: 9.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 94 QVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQ-LAQANILSVDTDDDGMLVEQLADLLETT---RVKAVYL 169
Cdd:cd01494 19 KAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVAAeLAGAKPVPVPVDDAGYGGLDVAILEELKakpNVALIVI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 170 VPTFGNPGGktlsEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAvelsceDqvVYTSTFSKILApGMRIG 249
Cdd:cd01494 99 TPNTTSGGV----LVPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIPEGGA------D--VVTFSLHKNLG-GEGGG 165
|
....
gi 489006153 250 WIVM 253
Cdd:cd01494 166 VVIV 169
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
66-278 |
2.65e-07 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 52.11 E-value: 2.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLL-DPGDTIVV---ERPTYLAALQVFQLAQANI 140
Cdd:PLN02368 103 YSDSRGLPGVRKEVAEFIERRdGYPSDPELIFLTDGASKGVMQILNAVIrGEKDGVLVpvpQYPLYSATISLLGGTLVPY 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 141 LSVDTDDDGMLVEQLADLLETTRVKA------VYLVPtfGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTD- 213
Cdd:PLN02368 183 YLEESENWGLDVNNLRQSVAQARSKGitvramVIINP--GNPTGQCLSEANLREILKFCYQERLVLLGDEVYQQNIYQDe 260
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489006153 214 ----AVRRPLYQHAVELSCEDQVVYTSTFSKILAP--GMRIGWIVMPDwLAQQTV--IVKQAA-DLHTNMLSQV 278
Cdd:PLN02368 261 rpfiSAKKVLMDMGPPISKEVQLVSFHTVSKGYWGecGQRGGYFEMTN-IPPKTVeeIYKVASiALSPNVSGQI 333
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
30-253 |
4.18e-07 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 51.66 E-value: 4.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 30 VISLGGGIPAPelFDTEGLELAVQKvMSERFNDAFQYGLTEGYPPLRQAVSEICHSRGV-ACSAAQVYITSGSQQSLDIV 108
Cdd:PRK13355 148 ILKLNIGNPAP--FGFRTPDEVVYD-MAQQLTDTEGYSDSKGLFSARKAIMQYAQLKGLpNVDVDDIYTGNGVSELINLS 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 109 ARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGMLVEQLADLLE--TTRVKAVYLV-PTfgNPGGKTLSEAR 185
Cdd:PRK13355 225 MSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHYRCDEQSEWYPDIDDIRSkiTSRTKAIVIInPN--NPTGALYPREV 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 186 RRRLVELAKKYDFVILEDDPYGEISFTDAVRRPLYQHAVELSCedqVVYtSTFSK--ILApGMRIGWIVM 253
Cdd:PRK13355 303 LQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIASLAPDLFC---VTF-SGLSKshMIA-GYRIGWMIL 367
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
30-211 |
6.84e-07 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 50.69 E-value: 6.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 30 VISLGGG---IPAPElFDTEGLELAVQKVMSERfndafqYGLTEGYPPLRQAVSEIcHSR--GVAC-SAAQVYITSGSQQ 103
Cdd:PRK08068 34 VINLGQGnpdQPTPE-HIVEALQEAAENPANHK------YSPFRGYPFLKEAAADF-YKReyGVTLdPETEVAILFGGKA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 104 SLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVD-TDDDGMLV--EQL-ADLLEttRVKAVYL-VPTfgNPGG 178
Cdd:PRK08068 106 GLVELPQCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPlIAENNFLPdyTKIpEEVAE--KAKLMYLnYPN--NPTG 181
|
170 180 190
....*....|....*....|....*....|...
gi 489006153 179 KTLSEARRRRLVELAKKYDFVILEDDPYGEISF 211
Cdd:PRK08068 182 AVATKAFFEETVAFAKKHNIGVVHDFAYGAIGF 214
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
30-255 |
9.22e-07 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 50.49 E-value: 9.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 30 VISLGGGIPA--PELFDTEGLELAVQKVMseRFNDAFQYGLTEGYPPLRQAVSEIChSRGV--ACSAAQVYITSGSQQSL 105
Cdd:PLN02187 68 ILPLGHGDPSvyPCFRTCIEAEDAVVDVL--RSGKGNSYGPGAGILPARRAVADYM-NRDLphKLTPEDIFLTAGCNQGI 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 106 DIVARTLLDPGDTIVVERPTY-----LAALQVFQLAQANIL---SVDTDDDGmlVEQLADllETTrVKAVYLVPTfgNPG 177
Cdd:PLN02187 145 EIVFESLARPNANILLPRPGFphydaRAAYSGLEVRKFDLLpekEWEIDLEG--IEAIAD--ENT-VAMVVINPN--NPC 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 178 GKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDavrRPLyqhaVELSCEDQVVYTSTFSKI----LAPGMRIGWIVM 253
Cdd:PLN02187 218 GNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGD---NPF----VSMGKFASIVPVLTLAGIskgwVVPGWKIGWIAL 290
|
..
gi 489006153 254 PD 255
Cdd:PLN02187 291 ND 292
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
51-356 |
1.44e-06 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 49.75 E-value: 1.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 51 AVQKVMSERFNDAFQYGLTEGyPPLRQAVSEichSRGVacSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAAL 130
Cdd:PRK05166 53 AVRRAFADIAELLRLYPDPQG-RALREAIAA---RTGV--PADRIILGNGSEDLIAVICRAVLRPGDRVVTLYPSFPLHE 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 131 QVFQLAQANILSVD-TDDDGMLVEQLADLLetTRVKAVYLVPTFGNPGGKTLSEARRRRLVElAKKYDFVILEDDPYGEI 209
Cdd:PRK05166 127 DYPTMMGARVERVTvTPDLGFDLDALCAAV--ARAPRMLMFSNPSNPVGSWLTADQLARVLD-ATPPETLIVVDEAYAEY 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 210 SFTDAvrrplYQHAVELSCEDQV--VYTSTFSKI--LApGMRIGWIVMPDwlAQQTVIVKQAAD-LHTNMLSQVITaeyl 284
Cdd:PRK05166 204 AAGDD-----YPSALTLLKARGLpwIVLRTFSKAygLA-GLRVGYGLVSD--PELVGLLDRVRTpFNVNGAAQAAA---- 271
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489006153 285 slnrldnQIALIREDYRKKCVALADALESRLGEHLE----FSRPQGGMFLWARFRYPFDTMEwmKKTLENGVVYVP 356
Cdd:PRK05166 272 -------LAALDDEEHLAKGVALALAERERLKKELAemgyRIAPSRANFLFFDARRPASAVA--EALLRQGVIVKP 338
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
21-382 |
2.73e-06 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 49.09 E-value: 2.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 21 LLKHSKLPGVISLGGGIPApelfdteglelaVQKVMSerFN-DAFQYGLTEG-----YP-----------PLRQ-AVSEI 82
Cdd:PRK09275 87 LEEHKDVPGIDFLRDAVSY------------VRDQLG--FDaDEFVYELVDGiigdnYPvpdrmlkhtekIVKDyLRQEM 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 83 CHSRGVACS----------AAQVYITsgsqQSLdiVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGML- 151
Cdd:PRK09275 153 CGGRPPKGEfdlfaveggtAAMCYIF----DSL--KENGLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADEENe 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 152 -------VEQLADlletTRVKAVYLV-PTfgNPGGKTLSEARRRRLVELAKKY--DFVILEDDPYGeiSFTDAVRRpLYQ 221
Cdd:PRK09275 227 wqypdseLEKLRD----PSIKALFLVnPS--NPPSVAMSDESLEKIADIVNEKrpDLMIITDDVYG--TFVDDFRS-LFA 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 222 havELSCEDQVVYtsTFSKIL-APGMRIGWI------VMPDWLAQQTVIVKQA----------------------AD--- 269
Cdd:PRK09275 298 ---VLPYNTILVY--SFSKYFgATGWRLGVIalhednVFDKLIAKLPEEKKKEldkrysslttdpeklkfidrlvADsrq 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 270 --L-HTNMLS---QVITAEYLSLNRLDNQialirEDYRKKCVALADALESRLGEHLEFSRPQGG----------MFLWAR 333
Cdd:PRK09275 373 vaLnHTAGLStpqQVQMALFSLFALLDEE-----DAYKKAMKDIIRRRYKALYEGLGLPEPEDPnnaayytlidLEEWAE 447
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 334 FRYPFDTMEWMKKTL-----------ENGVVYVPGEAFYHDKPDTRtlrlsystVSEAGL 382
Cdd:PRK09275 448 KNYGKEFADYLKKNYspvdllfrlaeETGVVLLPGGGFGGPEWSVR--------VSLANL 499
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
42-360 |
5.33e-06 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 48.40 E-value: 5.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 42 LFDTEGLELAVQKVMSERFNDAFQYGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLL-DPGDTI 119
Cdd:PLN02231 140 LFSADAIERAWQILDQIPGRATGAYSHSQGIKGLRDAIAAGIEARdGFPADPNDIFLTDGASPAVHMMMQLLIrSEKDGI 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 120 VVERPTYLAALQVFQLAQANILSVDTDDD---GMLVEQLADLLETTRVKAV----YLVPTFGNPGGKTLSEARRRRLVEL 192
Cdd:PLN02231 220 LCPIPQYPLYSASIALHGGTLVPYYLDEAtgwGLEISELKKQLEDARSKGItvraLVVINPGNPTGQVLAEENQRDIVEF 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 193 AKKYDFVILEDDPYGEISFTD--------AVRRPLYQHAVELScedqVVYTSTFSKIL--APGMRIGWIVMPDWLAQ-QT 261
Cdd:PLN02231 300 CKQEGLVLLADEVYQENVYVPdkkfhsfkKVARSMGYGEKDIS----LVSFQSVSKGYygECGKRGGYMEVTGFTSDvRE 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 262 VIVKQAA-DLHTNMLSQVITAEYLSLNRL-----DNQIAL---IREDYRKKCVALADALESRlgEHLEFSRPQGGMFLWA 332
Cdd:PLN02231 376 QIYKVASvNLCSNISGQILASLVMSPPKPgdesyESYMAEkdgILSSLARRAKTLEDALNSL--EGVTCNKAEGAMYLFP 453
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 489006153 333 RFRYP---FDTMEWMKKTLEN----------GVVYVPGEAF 360
Cdd:PLN02231 454 RIHLPqkaIKAAEAAKTAPDAfyckrllnatGIVVVPGSGF 494
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
97-391 |
7.15e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 47.84 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 97 ITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTD----DDGMLVEqLADLLETTRVKA-VYLVP 171
Cdd:PRK06207 107 ITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDylsaDKRAGLD-LDQLEEAFKAGVrVFLFS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 172 TFGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVrrplYQHAVELSCEDQVVYTstfskILAP------- 244
Cdd:PRK06207 186 NPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTS----YTHLRALPIDPENVIT-----IMGPsktesls 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 245 GMRIGWIVMPDWLAQQTVIVKQAADLHTNMLSQVITAEYLSLNR--LDNQIAL---IREDyrkkcvaLADALESRLGehL 319
Cdd:PRK06207 257 GYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVLRTWFSEPDgwMKDRIARhqaIRDD-------LLRVLRGVEG--V 327
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489006153 320 EFSRPQGGMFLWARF-RYPFDTMEWMKKT-LENGVVYVPGEAFyhDKPDTRTLRLSYSTvSEAGLLTAVERLAA 391
Cdd:PRK06207 328 FVRAPQAGSYLFPRLpRLAVSLHDFVKILrLQAGVIVTPGTEF--SPHTADSIRLNFSQ-DHAAAVAAAERIAQ 398
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
66-360 |
2.56e-05 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 45.82 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAVSEICHSR-GVACSA-AQVYITSGSQQSLDIVARTLLDPGDTIVVERPTY--------LAALQVFQL 135
Cdd:PRK07366 64 YLLFHGTLDFREAAAQWYEQRfGLAVDPeTEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPGYpshaggvyLAGGQIYPM 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 136 AqaniLSVDTDddgmLVEQLADLLETTRVKAVYLVPTF-GNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDA 214
Cdd:PRK07366 144 P----LRAEND----FLPVFADIPTEVLAQARLMVLSYpHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGE 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 215 VRRP-LYQHAVELSCEDQVVytsTFSKIL-APGMRIGWIVMPDWLAQQTVIVKQAADLHT--NMLSQVITAeylsLNRLD 290
Cdd:PRK07366 216 VEPPsILQADPEKSVSIEFF---TLSKSYnMGGFRIGFAIGNAQLIQALRQVKAVVDFNQyrGILNGAIAA----LTGPQ 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489006153 291 NQIALIREDYRKKCVALADALeSRLGEHLefSRPQGGMFLWARFRYPF--DTMEWMKKTLEN-GVVYVPGEAF 360
Cdd:PRK07366 289 ATVQQTVQIFRQRRDAFINAL-HQIGWPV--PLPEATMYVWAKLPEPWqgNSVEFCTQLVAQtGVAASPGSGF 358
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
66-360 |
3.05e-05 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 45.85 E-value: 3.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 66 YGLTEGYPPLRQAVSEICHSR-GVACSAAQVYITSGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVD 144
Cdd:COG1168 60 FGYTAPPDEYYEAIIDWLKRRhGWEIDPEWIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENP 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 145 -TDDDG---MLVEQLADLLeTTRVKAVYLV-PtfGNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDAVRRPl 219
Cdd:COG1168 140 lILEDGryrIDFDDLEAKL-DPGVKLLLLCnP--HNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHKHTP- 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 220 YQHAVELSCEDQVVYTSTfSK---IlaPGMRIGWIVMPD-WLAQQTVIVKQAADLH-TNMLSQV-ITAEYlslnR----- 288
Cdd:COG1168 216 FASLSEEAADRTITLTSP-SKtfnL--AGLKASYAIIPNpALRARFARALEGLGLPsPNVLGLVaTEAAY----Regeew 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489006153 289 LDNQIALIREDYRkkcvALADALESRLGEhLEFSRPQGGMFLWARFR-YPFDTMEWMKKTLEN-GVVYVPGEAF 360
Cdd:COG1168 289 LDELLAYLRGNRD----LLAEFLAEHLPG-VKVTPPEATYLAWLDCRaLGLDDEELAEFLLEKaGVALSDGATF 357
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
175-358 |
3.22e-05 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 45.45 E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 175 NPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEIsftdavrrplYQHA-----VELSCEdqvVYTSTFSKIL------- 242
Cdd:PRK05839 166 NPTGRTLSLEELIEWVKLALKHDFILINDECYSEI----------YENTpppslLEASIL---VGNESFKNVLvinsisk 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 243 ---APGMRIGWI-----VMPDWLAQQTViVKQAADLHTNMLSQVITAEylslnrlDNQIALIREDYRKKcVALADalesr 314
Cdd:PRK05839 233 rssAPGLRSGFIagdasILKKYKAYRTY-LGCASPLPLQKAAAVAWLD-------DEHAEFFRNIYAKN-LKLAR----- 298
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 489006153 315 lgEHLEFSRPQGGMFLWARFRypfDTMEWMKKTLEN-GVVYVPGE 358
Cdd:PRK05839 299 --EILGITIPPATFYVWLPVD---NDEEFTKKLYQNeGIKVLPGS 338
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
156-360 |
1.17e-04 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 43.87 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 156 ADLLEttRVKAVYL-VPTfgNPGGKTLSEARRRRLVELAKKYDFVILEDDPYGEISFTDavrRPLYQHAVELSCEDQVVY 234
Cdd:PRK06290 174 KDIKE--KAKLLYLnYPN--NPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG---KPLSFLSVPGAKEVGVEI 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 235 TStFSKIL-APGMRIGWIVmpdwlaQQTVIVKQAADLHTNMLS-QVITAEYLSLNRLDNQ--IALIREDYRKKCVALADA 310
Cdd:PRK06290 247 HS-LSKAYnMTGWRLAFVV------GNELIVKAFATVKDNNDSgQFIAIQKAGIYALDHPeiTEKIREKYSRRLDKLVKI 319
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 489006153 311 LESrLGehLEFSRPQGGMFLWarFRYPfdtmewmkKTLENGVVYVPGEAF 360
Cdd:PRK06290 320 LNE-VG--FKAEMPGGTFYLY--VKAP--------KGTKSGIKFENAEEF 356
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
115-203 |
3.53e-04 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 42.14 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 115 PGDTIVVERPTYLAALQVFQLAQANILSVDTDDD--GMLVEQLADLLeTTRVKAVYLVPTFGNPggktlseARRRRLVEL 192
Cdd:cd00616 57 PGDEVIVPSFTFVATANAILLLGATPVFVDIDPDtyNIDPELIEAAI-TPRTKAIIPVHLYGNP-------ADMDAIMAI 128
|
90
....*....|.
gi 489006153 193 AKKYDFVILED 203
Cdd:cd00616 129 AKRHGLPVIED 139
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
77-203 |
2.26e-03 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 39.67 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 77 QAVSEICHSR-GVACSAAqvyiTSGsqqsLDIVARTL-LDPGDTIVVerP--TYLAALQVFQLAQANILSVDTD-DDGML 151
Cdd:COG0399 37 EEFAAYLGVKhAVAVSSG----TAA----LHLALRALgIGPGDEVIT--PafTFVATANAILYVGATPVFVDIDpDTYNI 106
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 489006153 152 -VEQLADLLeTTRVKAVYLVPTFGNPggktlseARRRRLVELAKKYDFVILED 203
Cdd:COG0399 107 dPEALEAAI-TPRTKAIIPVHLYGQP-------ADMDAIMAIAKKHGLKVIED 151
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
56-197 |
2.87e-03 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 39.12 E-value: 2.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 56 MSERFNDAFQ----YGLTEGYPPLRQAVSEICHSrgvacsAAQVYITSGSQQSLdIVARTLLDPGDTIVVERP--TYL-- 127
Cdd:pfam01212 14 MREAMAAAMVgdevYGGDPTVNRLEDRVAELFGK------EAALFVPSGTAANQ-LALMAHCQRGDEVICGEPahIHFde 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489006153 128 -AALQVFQLAQAniLSVDTDDDG-MLVEQLADLLETT------RVKAVYLVPTFGNPGGKTLSEARRRRLVELAKKYD 197
Cdd:pfam01212 87 tGGHAELGGVQP--RPLDGDEAGnMDLEDLEAAIREVgadifpPTGLISLENTHNSAGGQVVSLENLREIAALAREHG 162
|
|
| PRK09105 |
PRK09105 |
pyridoxal phosphate-dependent aminotransferase; |
99-258 |
8.77e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181651 Cd Length: 370 Bit Score: 38.10 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 99 SGSQQSLDIVARTLLDPGDTIVVERPTYLAALQVFQLAQANILSVDTDDDGmlveqladlleTTRVKA---------VYL 169
Cdd:PRK09105 102 AGSSEPLNYAVLAFTSPTAGLVTADPTYEAGWRAADAQGAPVAKVPLRADG-----------AHDVKAmlaadpnagLIY 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489006153 170 VPTFGNPGGKTLSEARRRRLVElAKKYDFVILEDDPYgeISFTDAvrrplyQHAVELSCEDQ-VVYTSTFSKILA-PGMR 247
Cdd:PRK09105 171 ICNPNNPTGTVTPRADIEWLLA-NKPAGSVLLVDEAY--IHFSDA------PSVVDLVAQRKdLIVLRTFSKLYGmAGMR 241
|
170
....*....|..
gi 489006153 248 IGW-IVMPDWLA 258
Cdd:PRK09105 242 LGLaAARPDLLA 253
|
|
| |
