|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-314 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 610.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAG 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDFED 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARS-RVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 164 VVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKR 243
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLD-ADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489048332 244 VFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-314 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 550.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 1 MPDMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 81 SAGRITAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERD 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR-PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 161 FEDVVVVSPDIGGVVRARAIAKLLnDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHG 240
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489048332 241 AKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-314 |
3.86e-156 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 438.64 E-value: 3.86e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFIL-QSTCAPTNDNLMELIVMVDALRRASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDFE 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKS-REPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 163 DVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQA-NVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGA 241
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALG-CPLAIIDKRRISAtNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489048332 242 KRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSdelKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-121 |
7.89e-74 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 222.68 E-value: 7.89e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAG 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 489048332 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVG 121
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKP-REPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-274 |
2.82e-26 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 100.93 E-value: 2.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 149 SPVLLEDMKERDFEDVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVM------HIIGDVEGRDCIIVDDM 222
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALG-LPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 489048332 223 IDTGGTLCKAAEALKEHGAKRVFAYATHPILSGKAAEnlRDSMIDEVIVTDS 274
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-314 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 610.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAG 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDFED 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARS-RVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 164 VVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKR 243
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLD-ADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489048332 244 VFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-314 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 550.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 1 MPDMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 81 SAGRITAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERD 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR-PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 161 FEDVVVVSPDIGGVVRARAIAKLLnDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHG 240
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489048332 241 AKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
2-313 |
3.73e-161 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 452.08 E-value: 3.73e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 2 PDMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRAS 81
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 82 AGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDM-KERD 160
Cdd:PRK04923 85 AASVTAVIPYFGYSRQDRRMRSSRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIwRAYG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 161 FEDVVVVSPDIGGVVRARAIAKLLNDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHG 240
Cdd:PRK04923 165 TDNLIVVSPDVGGVVRARAVAKRLDDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQRG 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489048332 241 AKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKALDKVKVLTLADMLAETIRRISNEESISAMF 313
Cdd:PRK04923 245 ALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-314 |
3.86e-156 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 438.64 E-value: 3.86e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFIL-QSTCAPTNDNLMELIVMVDALRRASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDFE 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKS-REPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 163 DVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQA-NVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGA 241
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALG-CPLAIIDKRRISAtNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489048332 242 KRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSdelKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
4-313 |
5.56e-141 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 401.04 E-value: 5.56e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAG 83
Cdd:PRK02812 22 LRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 84 RITAVIPYFGYARQDRRVrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDFED 163
Cdd:PRK02812 102 QITAVIPYYGYARADRKT-AGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASKNLED 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 164 VVVVSPDIGGVVRARAIAKLLNDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKR 243
Cdd:PRK02812 181 IVVVSPDVGGVARARAFAKKLNDAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQ 260
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 244 VFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMF 313
Cdd:PRK02812 261 VYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEE-RRFPQLKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
13-313 |
5.90e-141 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 400.22 E-value: 5.90e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 13 PELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAGRITAVIPYF 92
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 93 GYARQDRRvRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDF--EDVVVVSPD 170
Cdd:PLN02369 81 GYARADRK-TQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTIssPDLVVVSPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 171 IGGVVRARAIAKLLNDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVFAYATH 250
Cdd:PLN02369 160 VGGVARARAFAKKLSDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATH 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489048332 251 PILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMF 313
Cdd:PLN02369 240 AVFSPPAIERLSSGLFQEVIVTNTIPVSEK-NYFPQLTVLSVANLLGETIWRVHDDCSVSSIF 301
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
3-314 |
4.02e-135 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 386.07 E-value: 4.02e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 3 DMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASA 82
Cdd:PRK02269 5 DLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDF- 161
Cdd:PRK02269 85 ESINVVMPYYGYARQDRKARS-REPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLv 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 162 -EDVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRP--QANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKE 238
Cdd:PRK02269 164 gDDVVVVSPDHGGVTRARKLAQFLK-TPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADALAE 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489048332 239 HGAKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:PRK02269 243 AGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEE-RLIDKIEQISIADLLGEAIIRIHEKRPLSPLFE 317
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
15-314 |
2.51e-122 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 352.71 E-value: 2.51e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 15 LAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAGRITAVIPYFGY 94
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 95 ARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKER-DFEDVVVVSPDIGG 173
Cdd:PRK03092 81 ARQDKKHR-GREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKyDLDNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 174 VVRARAIAKLLNDTDLAIIDKRRP--QANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVFAYATHP 251
Cdd:PRK03092 160 VRVAEQWADRLGGAPLAFIHKTRDptVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHG 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489048332 252 ILSGKAAENLRDSMIDEVIVTDSIPLSDElKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:PRK03092 240 VLSGPAAERLKNCGAREVVVTDTLPIPEE-KRFDKLTVLSIAPLLARAIREVFEDGSVTSLFD 301
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
1-313 |
2.33e-117 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 345.32 E-value: 2.33e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 1 MPDMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRA 80
Cdd:PTZ00145 117 MENAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 81 SAGRITAVIPYFGYARQDRRVrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFD--VPVDNVFGSPVLLEDMKE 158
Cdd:PTZ00145 197 SAKKITAVIPYYGYARQDRKL-SSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTK 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 159 RDFEDVVVVSPDIGGVVRARA-----IAKLLNDTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAA 233
Cdd:PTZ00145 276 KDLYKPVIVSPDAGGVYRARKfqdglNHRGISDCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAA 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 234 EALKEHGAKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKALDKVKVLTLADMLAETIRRISNEESISAMF 313
Cdd:PTZ00145 356 KQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLF 435
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
2-315 |
1.38e-105 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 310.90 E-value: 1.38e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 2 PDMKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRAS 81
Cdd:PRK02458 8 KQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 82 AGRITAVIPYFGYARQDrRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKERDF 161
Cdd:PRK02458 88 ANTVNVVLPYFGYARQD-RIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 162 --EDVVVVSPDIGGVVRARAIAKLLnDTDLAIIDKRRPQANVSQvMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEH 239
Cdd:PRK02458 167 sgSDVVVVSPKNSGIKRARSLAEYL-DAPIAIIDYAQDDSEREE-GYIIGDVAGKKAILIDDILNTGKTFAEAAKIVERE 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489048332 240 GAKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKAldKVKVLTLADMLAETIRRISNEESISAMFEH 315
Cdd:PRK02458 245 GATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPK--NVTYLSASELIADAIIRIHERKPLSPLFAY 318
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
6-314 |
5.54e-102 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 302.22 E-value: 5.54e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 6 LFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAGRI 85
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 86 TAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLL----EDMKERdf 161
Cdd:PRK00553 92 TAILPYYGYARQDRKTA-GREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLsrvlELLGKK-- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 162 eDVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGA 241
Cdd:PRK00553 169 -DLVVVSPDYGGVKRARLIAESLE-LPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKA 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489048332 242 KRVFAYATHPILSGKAAENLRDS----MIDEVIVTDSIPLSdELKALDKVKVLTLADMLAETIRRISNEESISAMFE 314
Cdd:PRK00553 247 KKVCVMATHGLFNKNAIQLFDEAfkkkLIDKLFVSNSIPQT-KFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYT 322
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-121 |
7.89e-74 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 222.68 E-value: 7.89e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 4 MKLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPTNDNLMELIVMVDALRRASAG 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 489048332 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVG 121
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKP-REPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
5-276 |
2.92e-71 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 222.10 E-value: 2.92e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 5 KLFAGNATPELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTcAPTNDNLMELIVMVDALRRASAGR 84
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTT-YPQDENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 85 ITAVIPYFGYARQDRRVRSARvPITAKVVADFLSSVGvDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKErDFEDV 164
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGE-PISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGD-KLDDP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 165 VVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRV 244
Cdd:PRK00934 157 LVLAPDKGALELAKEAAEILG-CEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKV 235
|
250 260 270
....*....|....*....|....*....|..
gi 489048332 245 FAYATHPILSGKAAENLRDSMIDEVIVTDSIP 276
Cdd:PRK00934 236 YVACVHPVLVGDAILKLYNAGVDEIIVTDTLE 267
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
34-310 |
5.16e-49 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 167.82 E-value: 5.16e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 34 RFSDGEISVQINENVRGSDVFILQSTC---------------APtNDNLMELIVMVDALRrASAGRITAVIPYFGYARQD 98
Cdd:PRK06827 61 RFSNGEAKGEILESVRGKDIYILQDVGnysvtynmfgeknhmSP-DDHFQDLKRTIDAIR-GKARRITVIMPFLYESRQH 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 99 RRvrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQ------GFfdvpvDNVFGS----PVLLEDMK--ERDFEDVVV 166
Cdd:PRK06827 139 KR--KGRESLDCALALQELEELGVDNIITFDAHDPRIEnaiplmGF-----ENLYPSyqiiKALLKNEKdlEIDKDHLMV 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 167 VSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQ-----VMH--IIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEH 239
Cdd:PRK06827 212 ISPDTGAMDRAKYYASVLG-VDLGLFYKRRDYSRVVNgrnpiVAHefLGRDVEGKDVLIVDDMIASGGSMIDAAKELKSR 290
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489048332 240 GAKRVFAYATHPILSG------KAAEnlrDSMIDEVIVTDSIPLSDELKALDKVKVLTLADMLAETIRRISNEESIS 310
Cdd:PRK06827 291 GAKKIIVAATFGFFTNglekfdKAYE---EGYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARIIDALNHDVSLS 364
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
7-302 |
2.49e-38 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 137.38 E-value: 2.49e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 7 FAGNAtpELAQKVAKRLYIELGDAVVGRFSDGEISVQINENVRGSDVFILQSTCAPtNDNLMELIVMVDALRRASAGRIT 86
Cdd:PRK07199 8 LPGNE--AAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 87 AVIPYFGYARQDRRVRSARVpITAKVVADFLSSVgVDRVLTVDLHAEQI---QGFFDVPVDNVFGSPVLLEDMKERDfED 163
Cdd:PRK07199 85 LVAPYLAYMRQDIAFHPGEA-ISQRHFARLLSGS-FDRLVTVDPHLHRYpslSEVYPIPAVVLSAAPAIAAWIRAHV-PR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 164 VVVVSPDIGGVVRARAIAKLLnDTDLAIIDKRR----------PQANVsqvmhiigdVEGRDCIIVDDMIDTGGTLCKAA 233
Cdd:PRK07199 162 PLLIGPDEESEQWVAAVAERA-GAPHAVLRKTRhgdrdveislPDAAP---------WAGRTPVLVDDIVSTGRTLIEAA 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489048332 234 EALKEHGAKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPlsDELKALDkvkvltLADMLAETIRR 302
Cdd:PRK07199 232 RQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVP--HPSNAIS------LAPLLAEALRR 292
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
6-300 |
9.17e-29 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 112.48 E-value: 9.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 6 LFAGNATPELAQKVAKR-LYIELGDAVVGRFSDGEISVQIN--ENVRGSDVFILQSTCAPtnDNLMELIVMVDALRRASA 82
Cdd:PLN02297 19 LFYCEETEELARKIAAEsDAIELGSINWRKFPDGFPNLFINnaHGIRGQHVAFLASFSSP--AVIFEQLSVIYALPKLFV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 83 GRITAVIPYFGYARQDRRVRSARVPiTAKVVADFLSSV-----GVDRVLTVDLHAEQIQGFFDvpvDNVF-----GSPVL 152
Cdd:PLN02297 97 ASFTLVLPFFPTGTSERVEREGDVA-TAFTLARILSNIpisrgGPTSLVIFDIHALQERFYFG---DNVLpcfesGIPLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 153 LEDMKE-RDFEDVVVVSPDIGGVVRaraIAKLLNDTDLAIIDKRRpQANVSQVMHIIGDVEGRDCIIVDDMIDTGGTLCK 231
Cdd:PLN02297 173 KKRLQQlPDSDNIVIAFPDDGAWKR---FHKQFEHFPMVVCTKVR-EGDKRIVRIKEGNPAGRHVVIVDDLVQSGGTLIE 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489048332 232 AAEALKEHGAKRVFAYATHPILSGKAAENLRDS------MIDEVIVTDSIPLS-DELKALDKVKVLTLADMLAETI 300
Cdd:PLN02297 249 CQKVLAAHGAAKVSAYVTHGVFPNESWERFTHDnggpeaGFAYFWITDSCPQTvKAVRGKAPFEVLSLAGSIADAL 324
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
205-313 |
1.42e-28 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 108.37 E-value: 1.42e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 205 MHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVFAYATHPILSGKAAENLRDSMIDEVIVTDSIPLSDELKAL 284
Cdd:pfam14572 75 MTVVGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQC 154
|
90 100
....*....|....*....|....*....
gi 489048332 285 DKVKVLTLADMLAETIRRISNEESISAMF 313
Cdd:pfam14572 155 HKIKTIDISQLIAEAIRRIHNGESMSYLF 183
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-274 |
2.82e-26 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 100.93 E-value: 2.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 149 SPVLLEDMKERDFEDVVVVSPDIGGVVRARAIAKLLNdTDLAIIDKRRPQANVSQVM------HIIGDVEGRDCIIVDDM 222
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALG-LPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 489048332 223 IDTGGTLCKAAEALKEHGAKRVFAYATHPILSGKAAEnlRDSMIDEVIVTDS 274
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
160-271 |
4.27e-16 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 73.94 E-value: 4.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 160 DFEDVVVVSPDIGGVVRARAIAKLLnDTDLAIIDKRRPQANVSQVM---HIIGDVEGRDCIIVDDMIDTGGTLCKAAEAL 236
Cdd:pfam00156 27 GGKPDVVVGILRGGLPFAGILARRL-DVPLAFVRKVSYNPDTSEVMktsSALPDLKGKTVLIVDDILDTGGTLLKVLELL 105
|
90 100 110
....*....|....*....|....*....|....*
gi 489048332 237 KEHGAKRVFAYATHPILSGKAAENLRDSMIDEVIV 271
Cdd:pfam00156 106 KNVGPKEVKIAVLIDKPAGTEPKDKYDKRVDDWIV 140
|
|
| PyrE2 |
COG0856 |
Orotate phosphoribosyltransferase homolog [Nucleotide transport and metabolism]; |
151-244 |
1.51e-10 |
|
Orotate phosphoribosyltransferase homolog [Nucleotide transport and metabolism];
Pssm-ID: 440617 [Multi-domain] Cd Length: 201 Bit Score: 59.48 E-value: 1.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 151 VLLEDMKERDFEDVVVVSpdIGGVVRARAIAKLLnDTDLAII-------DKRRPQANVSQVMhiiGDVEGRDCIIVDDMI 223
Cdd:COG0856 78 MLLEELGDEEVDLVVGIA--KSGVPLATLVAEEL-GTELAIYhpakhqwEIEDLGGSFSRNF---ASVEGKRCVIVDDVI 151
|
90 100
....*....|....*....|.
gi 489048332 224 DTGGTLCKAAEALKEHGAKRV 244
Cdd:COG0856 152 TSGTTMTETIEAIREHGGEPV 172
|
|
| PRK02277 |
PRK02277 |
orotate phosphoribosyltransferase-like protein; Provisional |
155-244 |
4.48e-10 |
|
orotate phosphoribosyltransferase-like protein; Provisional
Pssm-ID: 235023 [Multi-domain] Cd Length: 200 Bit Score: 58.34 E-value: 4.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 155 DMKERDFEDV-VVVSPDIGGVVRARAIAKLLnDTDLAII--------DKRRPQANVSQVMhiiGDVEGRDCIIVDDMIDT 225
Cdd:PRK02277 77 DMLEKEDEEVdVVVGIAKSGVPLATLVADEL-GKDLAIYhpkkwdhgEGEKKTGSFSRNF---ASVEGKRCVIVDDVITS 152
|
90
....*....|....*....
gi 489048332 226 GGTLCKAAEALKEHGAKRV 244
Cdd:PRK02277 153 GTTMKETIEYLKEHGGKPV 171
|
|
| HptA |
COG0634 |
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; ... |
210-244 |
6.79e-08 |
|
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Hypoxanthine-guanine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 440399 Cd Length: 176 Bit Score: 51.57 E-value: 6.79e-08
10 20 30
....*....|....*....|....*....|....*
gi 489048332 210 DVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRV 244
Cdd:COG0634 88 DIEGRDVLIVEDIIDTGLTLSYLLELLKSRGPASV 122
|
|
| ComFC |
COG1040 |
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General ... |
177-248 |
7.97e-08 |
|
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General function prediction only];
Pssm-ID: 440662 [Multi-domain] Cd Length: 196 Bit Score: 51.75 E-value: 7.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 177 ARAIAKLLN---DTD-LAIIDKRRPQA---------NVSQVMHIIG--DVEGRDCIIVDDMIDTGGTLCKAAEALKEHGA 241
Cdd:COG1040 104 ARALARALGipvLPDlLRRVRATPSQAglsraerrrNLRGAFAVRPpaRLAGKHVLLVDDVLTTGATLAEAARALKAAGA 183
|
....*..
gi 489048332 242 KRVFAYA 248
Cdd:COG1040 184 ARVDVLV 190
|
|
| upp |
PRK00129 |
uracil phosphoribosyltransferase; Reviewed |
210-246 |
1.75e-07 |
|
uracil phosphoribosyltransferase; Reviewed
Pssm-ID: 234653 Cd Length: 209 Bit Score: 50.86 E-value: 1.75e-07
10 20 30
....*....|....*....|....*....|....*..
gi 489048332 210 DVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVFA 246
Cdd:PRK00129 121 DIDERTVIVVDPMLATGGSAIAAIDLLKKRGAKNIKV 157
|
|
| Hpt1 |
COG2236 |
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ... |
152-244 |
1.79e-07 |
|
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 441837 [Multi-domain] Cd Length: 153 Bit Score: 49.84 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 152 LLEDMKERDFE-DVVVVspdI--GGVVRARAIAKLLNDTDLAII--------DKRRPQANVSQvmHIIGDVEGRDCIIVD 220
Cdd:COG2236 21 LAEQILESGFRpDVIVA---IarGGLVPARILADALGVPDLASIrvssytgtAKRLEEPVVKG--PLDEDLAGKRVLIVD 95
|
90 100
....*....|....*....|....
gi 489048332 221 DMIDTGGTLCKAAEALKEHGAKRV 244
Cdd:COG2236 96 DVADTGRTLEAVRDLLKEAGPAEV 119
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
151-263 |
5.73e-05 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 43.22 E-value: 5.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 151 VLLEDMKERDFEDVVVVSPDIGGVVRARAIAKLLNdTDLAIIdkrRPQANVSQVMHII--GDVEGRDCIIVDDMIDTGGT 228
Cdd:COG0461 52 ALAELIKELGPEFDAVAGPATGGIPLAAAVARALG-LPAIFV---RKEAKDHGTGGQIegGLLPGERVLVVEDVITTGGS 127
|
90 100 110
....*....|....*....|....*....|....*..
gi 489048332 229 LCKAAEALKEHGAK--RVFAYATHpilSGKAAENLRD 263
Cdd:COG0461 128 VLEAVEALREAGAEvvGVAVIVDR---EEGAAENLEE 161
|
|
| PTZ00149 |
PTZ00149 |
hypoxanthine phosphoribosyltransferase; Provisional |
205-291 |
7.76e-04 |
|
hypoxanthine phosphoribosyltransferase; Provisional
Pssm-ID: 240293 Cd Length: 241 Bit Score: 40.14 E-value: 7.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 205 MHIIGD----VEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVfAYAT-----HPILSGKAAENLRDSMIDEVIVTDSI 275
Cdd:PTZ00149 138 LEIVSDdlscLKDKHVLIVEDIIDTGNTLVKFCEYLKKFEPKTI-RIATlfekrTPLSNGFKGDFVGFSIPDHFVVGYCL 216
|
90
....*....|....*.
gi 489048332 276 PLSDELKALDKVKVLT 291
Cdd:PTZ00149 217 DYNEHFRDLDHVAVLN 232
|
|
| PLN02238 |
PLN02238 |
hypoxanthine phosphoribosyltransferase |
210-244 |
1.20e-03 |
|
hypoxanthine phosphoribosyltransferase
Pssm-ID: 215132 Cd Length: 189 Bit Score: 39.25 E-value: 1.20e-03
10 20 30
....*....|....*....|....*....|....*
gi 489048332 210 DVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRV 244
Cdd:PLN02238 94 DVKGKHVLLVEDIVDTGNTLSALVAHLEAKGAASV 128
|
|
| pyrE |
PRK00455 |
orotate phosphoribosyltransferase; Validated |
152-242 |
1.49e-03 |
|
orotate phosphoribosyltransferase; Validated
Pssm-ID: 234771 Cd Length: 202 Bit Score: 38.98 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 152 LLEDMKERDFEDV-VVVSPDIGGVVRARAIAKLLNdtdL-AIIDKRRPQAnvsqvmH-----IIG-DVEGRDCIIVDDMI 223
Cdd:PRK00455 53 FLAEAIKDSGIEFdVVAGPATGGIPLAAAVARALD---LpAIFVRKEAKD------HgeggqIEGrRLFGKRVLVVEDVI 123
|
90
....*....|....*....
gi 489048332 224 DTGGTLCKAAEALKEHGAK 242
Cdd:PRK00455 124 TTGGSVLEAVEAIRAAGAE 142
|
|
| PRK02304 |
PRK02304 |
adenine phosphoribosyltransferase; Provisional |
205-242 |
1.70e-03 |
|
adenine phosphoribosyltransferase; Provisional
Pssm-ID: 235028 Cd Length: 175 Bit Score: 38.52 E-value: 1.70e-03
10 20 30
....*....|....*....|....*....|....*...
gi 489048332 205 MHIIGDVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAK 242
Cdd:PRK02304 106 IHKDAIKPGDRVLIVDDLLATGGTLEAAIKLLERLGAE 143
|
|
| PRK09162 |
PRK09162 |
hypoxanthine-guanine phosphoribosyltransferase; Provisional |
210-246 |
1.79e-03 |
|
hypoxanthine-guanine phosphoribosyltransferase; Provisional
Pssm-ID: 181675 Cd Length: 181 Bit Score: 38.69 E-value: 1.79e-03
10 20 30
....*....|....*....|....*....|....*..
gi 489048332 210 DVEGRDCIIVDDMIDTGGTLCKAAEALKEHGAKRVFA 246
Cdd:PRK09162 94 SLKGRTVLVVDDILDEGHTLAAIRDRCLEMGAAEVYS 130
|
|
| pyrE |
TIGR00336 |
orotate phosphoribosyltransferase; Orotate phosphoribosyltransferase (OPRTase) is involved in ... |
160-241 |
3.47e-03 |
|
orotate phosphoribosyltransferase; Orotate phosphoribosyltransferase (OPRTase) is involved in the biosynthesis of pyrimidine nucleotides. Alpha-D-ribosyldiphosphate 5-phosphate (PRPP) and orotate are utilized to form pyrophosphate and orotidine 5'-monophosphate (OMP) in the presence of divalent cations, preferably Mg2+. In a number of eukaryotes, this protein is fused to a domain that catalyses the reaction (EC 4.1.1.23). The combined activity of EC 2.4.2.10 and EC 4.1.1.23 is termed uridine 5'-monophosphate synthase. The conserved Lys (K) residue at position 101 of the seed alignment has been proposed as the active site for the enzyme. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]
Pssm-ID: 129436 [Multi-domain] Cd Length: 173 Bit Score: 37.79 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489048332 160 DFEDVVVVSPDIGGVVRARAIAKLLN----DTDLAIIDKRRPQANVSQvmHIIGDV-EGRDCIIVDDMIDTGGTLCKAAE 234
Cdd:TIGR00336 52 HLEFDVIAGPALGGIPIATAVSVKLAkpggDIPLCFNRKEAKDHGEGG--NIEGELlEGDKVVVVEDVITTGTSILEAVE 129
|
....*..
gi 489048332 235 ALKEHGA 241
Cdd:TIGR00336 130 IIQAAGG 136
|
|
| PLN02293 |
PLN02293 |
adenine phosphoribosyltransferase |
204-244 |
8.71e-03 |
|
adenine phosphoribosyltransferase
Pssm-ID: 177930 Cd Length: 187 Bit Score: 36.58 E-value: 8.71e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 489048332 204 VMHIiGDVE-GRDCIIVDDMIDTGGTLCKAAEALKEHGAKRV 244
Cdd:PLN02293 116 EMHV-GAVEpGERALVIDDLIATGGTLCAAINLLERAGAEVV 156
|
|
| |
