|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 823.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFV 79
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRpGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 80 AEVEKLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRP 159
Cdd:PRK01117 81 KEIDELEARGVDV-RERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 160 KVERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVT 238
Cdd:PRK01117 160 KLEENLEYKNFLLTKYyGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 239 SSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTV 318
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 319 RTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVR 398
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 489054606 399 HIEELIGAPVAMLSTSPEREDTILVTDPFHD 429
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 760.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAE 81
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRpGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVTPDvLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:COG0104 81 IDGLEARGVDVRSR-LRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSS 240
Cdd:COG0104 160 EELLEYKNFLLEKLyGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 241 NTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRT 320
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 321 SGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHI 400
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|...
gi 489054606 401 EELIGAPVAMLSTSPEREDTILV 423
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-421 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 729.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAEVE 83
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNpGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 84 KLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVER 163
Cdd:pfam00709 81 ELEERGIDV-PDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 164 LLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTV 243
Cdd:pfam00709 160 LLELKNKLLEKLYGEPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 244 AGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 324 NGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*...
gi 489054606 404 IGAPVAMLSTSPEREDTI 421
Cdd:pfam00709 400 LGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-422 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 712.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAE 81
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNpNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVTpDVLRVAENAPLILSIHRELDAMREGSnsglKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:smart00788 81 IEELEAKGVDVK-DRLFISDRAHLILPYHIALDKAREKA----RIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSS 240
Cdd:smart00788 156 EELLDYKNFLLKKLyGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 241 NTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRT 320
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 321 SGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHI 400
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 489054606 401 EELIGAPVAMLSTSPEREDTIL 422
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-427 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 539.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKL-SVIGNGVVVDPHHFVAEVE 83
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAkLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 84 KLRGQGIDVTpDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVER 163
Cdd:TIGR00184 81 YLEKRGISVR-DRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 164 LLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNT 242
Cdd:TIGR00184 160 ILEYLNEQLVKYyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 243 VAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSG 322
Cdd:TIGR00184 240 TAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 323 INGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEE 402
Cdd:TIGR00184 320 ATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*
gi 489054606 403 LIGAPVAMLSTSPEREDTILVTDPF 427
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKEL 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-422 |
4.92e-158 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 448.49 E-value: 4.92e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGK-LSVIGNGVVVDPHHFVAE 81
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNaTCVIGNGVVIDPPALFEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDltepetlrpkv 161
Cdd:cd03108 82 IEELEKKGIDV-KGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 erllahhnslrrgmgleeiavetilteltsvadqilPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSN 241
Cdd:cd03108 150 ------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSN 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 242 TVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTS 321
Cdd:cd03108 194 TTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRIN 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 322 GINGIALTKLDVldgleeikicvayeldgkridylpssmgaqarvkpiyetlpgwsettagarswndlpaQAVKYVRHIE 401
Cdd:cd03108 274 GLTELALTKLDV----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|.
gi 489054606 402 ELIGAPVAMLSTSPEREDTIL 422
Cdd:cd03108 296 ELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
3.29e-29 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 115.54 E-value: 3.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERA--DVIVRyQGGHNAGHTlVID--GVSYKLSLLPSGLVRGKLS--VIGNGVVVDPHHF 78
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAapDVVVR-AAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPLKqvLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 79 VAEVEKLRGQGIDVTpDVLRVAENAPLI-LSIHREldamrEGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDltepetl 157
Cdd:NF038379 81 REEIEELEDAGHDVG-KRLLIHEQATVIeLHKHVE-----EEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGD------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 158 rpkverllaHHNSLRRGMGLEEIAVETILTELTSVADQILpyidqvwrvlderrKAGARILFEGAQGALLDNDHGTYPFV 237
Cdd:NF038379 148 ---------AEGDFGEGAVRDQPWEIAERVVDNALYDFAL--------------QAAERIQIEGTQGYSLGLHAGFYPYC 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 238 TSSNTVAGQAAAGSGLGPTAI--GYVLGITKAYTTRVGE-----GPFPTELNdeiGEFLGTKgHEFGVVTGRKRRCGWFD 310
Cdd:NF038379 205 TSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETT---WEELGLP-EELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 489054606 311 AVIVRQTVRTSG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 823.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFV 79
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRpGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 80 AEVEKLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRP 159
Cdd:PRK01117 81 KEIDELEARGVDV-RERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 160 KVERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVT 238
Cdd:PRK01117 160 KLEENLEYKNFLLTKYyGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 239 SSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTV 318
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 319 RTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVR 398
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 489054606 399 HIEELIGAPVAMLSTSPEREDTILVTDPFHD 429
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 760.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAE 81
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRpGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVTPDvLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:COG0104 81 IDGLEARGVDVRSR-LRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSS 240
Cdd:COG0104 160 EELLEYKNFLLEKLyGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 241 NTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRT 320
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 321 SGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHI 400
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|...
gi 489054606 401 EELIGAPVAMLSTSPEREDTILV 423
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-421 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 729.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAEVE 83
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNpGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 84 KLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVER 163
Cdd:pfam00709 81 ELEERGIDV-PDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 164 LLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTV 243
Cdd:pfam00709 160 LLELKNKLLEKLYGEPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 244 AGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 324 NGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*...
gi 489054606 404 IGAPVAMLSTSPEREDTI 421
Cdd:pfam00709 400 LGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-422 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 712.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFVAE 81
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNpNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVTpDVLRVAENAPLILSIHRELDAMREGSnsglKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:smart00788 81 IEELEAKGVDVK-DRLFISDRAHLILPYHIALDKAREKA----RIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSS 240
Cdd:smart00788 156 EELLDYKNFLLKKLyGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 241 NTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRT 320
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 321 SGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHI 400
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 489054606 401 EELIGAPVAMLSTSPEREDTIL 422
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-427 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 539.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKL-SVIGNGVVVDPHHFVAEVE 83
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAkLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 84 KLRGQGIDVTpDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVER 163
Cdd:TIGR00184 81 YLEKRGISVR-DRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 164 LLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNT 242
Cdd:TIGR00184 160 ILEYLNEQLVKYyKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 243 VAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSG 322
Cdd:TIGR00184 240 TAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 323 INGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEE 402
Cdd:TIGR00184 320 ATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*
gi 489054606 403 LIGAPVAMLSTSPEREDTILVTDPF 427
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKEL 424
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-421 |
5.20e-177 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 501.09 E-value: 5.20e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVID-GVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHF 78
Cdd:PLN02513 2 SQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNeKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 79 VAEVEKLRGQGIDVTPDVLrVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLR 158
Cdd:PLN02513 82 FEEIDGLESNGVSCEGRLL-VSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 159 PKVERLLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVT 238
Cdd:PLN02513 161 EKLRELLADAAARFEGFEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 239 SSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTV 318
Cdd:PLN02513 241 SSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSC 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 319 RTSGINGIALTKLDVLDGLEEIKICVAYEL-DGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYV 397
Cdd:PLN02513 321 QINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYV 400
|
410 420
....*....|....*....|....
gi 489054606 398 RHIEELIGAPVAMLSTSPEREDTI 421
Cdd:PLN02513 401 ERIEELVGVPVHYIGVGPGRDALI 424
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
4-424 |
1.37e-164 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 469.89 E-value: 1.37e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 4 VVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSG-LVRGKLSVIGNGVVVDPHHFVAEV 82
Cdd:PTZ00350 15 VVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGiLYPNCINVLGNGVVIHLPSLLEEI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 83 EKLRGQGIDVTpDVLRVAENAPLILSIHRELDAMREGSN--SGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPK 160
Cdd:PTZ00350 95 EQLTKKGINLL-GRLYISDRAHLVFDLHQAIDGIQESEKgkGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 161 VERLLAHHNSLrrgMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSS 240
Cdd:PTZ00350 174 YRKLVEKLQEQ---YNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSS 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 241 NTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRT 320
Cdd:PTZ00350 251 NTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQMI 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 321 SGINGIALTKLDVLDGLEEIKICVAYELDGK--RIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVR 398
Cdd:PTZ00350 331 NGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKYVL 410
|
410 420
....*....|....*....|....*.
gi 489054606 399 HIEELIGAPVAMLSTSPEREDTILVT 424
Cdd:PTZ00350 411 FIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-422 |
4.92e-158 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 448.49 E-value: 4.92e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGK-LSVIGNGVVVDPHHFVAE 81
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNaTCVIGNGVVIDPPALFEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDltepetlrpkv 161
Cdd:cd03108 82 IEELEKKGIDV-KGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 erllahhnslrrgmgleeiavetilteltsvadqilPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSN 241
Cdd:cd03108 150 ------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSN 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 242 TVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTS 321
Cdd:cd03108 194 TTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRIN 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 322 GINGIALTKLDVldgleeikicvayeldgkridylpssmgaqarvkpiyetlpgwsettagarswndlpaQAVKYVRHIE 401
Cdd:cd03108 274 GLTELALTKLDV----------------------------------------------------------NAQKYIERIE 295
|
410 420
....*....|....*....|.
gi 489054606 402 ELIGAPVAMLSTSPEREDTIL 422
Cdd:cd03108 296 ELLGVPITYISVGPDREQTII 316
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-421 |
7.13e-145 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 419.21 E-value: 7.13e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVEK 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARVLIGPGVVLNPEVLAEEIDM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 85 LRGQGIDVTPDVLRVAENAPLILSIHRELDAMREGSNSGlKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVERL 164
Cdd:PRK13786 84 LEKHGVKVDAEKLGIDAKTSIIMPYHIELDGLRESARTE-KIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 165 LAHHNSLRRGMGLEEIAV--ETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNT 242
Cdd:PRK13786 163 APQKEKEIKELGGDPSIVrdEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTSSST 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 243 VAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSG 322
Cdd:PRK13786 243 IAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIYLNG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 323 INGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEE 402
Cdd:PRK13786 323 YTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVERLEE 402
|
410
....*....|....*....
gi 489054606 403 LIGAPVAMLSTSPEREDTI 421
Cdd:PRK13786 403 LMGVPIKYISVGPGREQTF 421
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
4-427 |
5.75e-137 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 400.29 E-value: 5.75e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 4 VVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVE 83
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKIGVLGNGCVVNPETLFDEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 84 KLRGQGIDvtPDVlRVAENAPLILSIHRELDAMRE--GSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:PRK13785 83 ALRERGLD--PDV-RVAERAHVILPYHRVLDGIEEeaKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSL-------RRGMGLEEIAVETILTELTSVADQILpyiDQVWRV-----LDERRKAGARILFEGAQGALLDN 229
Cdd:PRK13785 160 EYVVPQKRALaedvyglDASETPEAFDVDALFEEYREYGERLA---EEDMTVnagdfLAERIDDGDNVMLEGAQGTSIDI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 230 DHGTYPFVTSSNTVAGQAAAGSGLGPTAI--GYVLGITKAYTTRVGEGPFPTEL---------------NDEIGEFLGTK 292
Cdd:PRK13785 237 DHGNYPYVTSSNPTAGGAATGTGLGPTVVgqGEVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 293 GHEFGVVTGRKRRCGWFDAVIVRQTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYET 372
Cdd:PRK13785 317 GGEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRS 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 489054606 373 LPGWSE---TTAGARSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTILVTDPF 427
Cdd:PRK13785 397 FDGWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-422 |
5.90e-132 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 386.23 E-value: 5.90e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGK-LSVIGNGVVVDPHHFV 79
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQtICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 80 AEVEKLRGQGIDVTPDVLrVAENAPLILSIHRELDAMRE-GSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEpETLR 158
Cdd:PRK13787 81 EECDRLQKEGFPVKDKLL-LSDACHLLFPYHSQIDSAREtTSSQEHKIGTTKKGIGICYADKMMRTGLRVGDLLD-KSYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 159 PKVERLLAHHN-SLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFV 237
Cdd:PRK13787 159 RRLKHLVDEKNrELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 238 TSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQT 317
Cdd:PRK13787 239 TSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 318 VRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSmgAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYV 397
Cdd:PRK13787 319 VRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQ--GLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYI 396
|
410 420
....*....|....*....|....*
gi 489054606 398 RHIEELIGAPVAMLSTSPEREDTIL 422
Cdd:PRK13787 397 SALEKWIGVKINLVSTGPDRKDTII 421
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-420 |
2.11e-131 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 384.16 E-value: 2.11e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVR-GKLSVIGNGVVVDPHHFV 79
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHpHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 80 AEVEKLRGQGIDvtPDVlRVAENAPLILSIHRELDAMREgsnsglKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRP 159
Cdd:PRK13788 81 EERENLRAGGLN--PKL-LISERAHLVLPHHKYVDGRKN------FVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 160 KVERLLAHHNSLRRGMGLEeiAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTS 239
Cdd:PRK13788 152 RVERLLEAKPNSTREAGWD--TVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 240 SNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKG----HEFGVVTGRKRRCGWFDAVIVR 315
Cdd:PRK13788 230 SHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 316 QTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGkridylpssmgaqarvKPIYETLPGWSEtTAGARSWNDLPAQAVK 395
Cdd:PRK13788 310 YACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWGD-LDGVKSREALPKEAQA 372
|
410 420
....*....|....*....|....*
gi 489054606 396 YVRHIEELIGAPVAMLSTSPEREDT 420
Cdd:PRK13788 373 YLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
3-421 |
4.16e-126 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 370.59 E-value: 4.16e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 3 NVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRG-KLSVIGNGVVVDPHHFVAE 81
Cdd:PRK13783 2 KRVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKnVGAAIGNGVVLDLEVLVEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 82 VEKLRGQGIDVtPDVLRVAENAPLILSIHRELDAMREgSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKV 161
Cdd:PRK13783 82 LEELKEKFPDY-SGRIFISELAHVVLPVHKELDEIIE-SVRKNAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 162 ERLLAHHNSLRRgmglEEIAVETILTELTSVADQILPYI---DQVWRVLDErrkagARILFEGAQGALLDNDHGTYPFVT 238
Cdd:PRK13783 160 EKILSLYKKLYG----IEFDVEKMMEDLLTFYEKIKDLVvspVEIKRILEE-----KSVLFEGTQGVLLDLDVGTYPYVT 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 239 SSNTVAGQAAAGSGLgPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTV 318
Cdd:PRK13783 231 SSNCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAI 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 319 RTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDyLPSSMGAQARVKPIYETLPGWSETTagarSWNDLpaqavKYVR 398
Cdd:PRK13783 310 EVSGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVR-DPSSLRDLEKAEPVYEEFDGWKSLE----DKNFL-----KFVD 379
|
410 420
....*....|....*....|...
gi 489054606 399 HIEELIGAPVAMLSTSPEREDTI 421
Cdd:PRK13783 380 FIERETGRKIAYISTGPKIEEIV 402
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-427 |
3.23e-114 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 341.23 E-value: 3.23e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLS-VIGNGVVVDPHHFV 79
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKcVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 80 AEVEKLRGQGIDVTPDVLRVAENAPLILSIHRELDAMREgSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRP 159
Cdd:PRK13784 81 EEITRLQAKGIAISAENLFVSESCTIITSYHKLLDAVRE-SNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 160 KVERLLAHHNSLRRGM-GLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLyKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 239 SSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTV 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 319 RTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIdYLPSSMGAQARVKPIYETLPGWSETTAGARswNDLPAQAVKYVR 398
Cdd:PRK13784 320 KCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI-YCAYPGIDLYKVEPILVEMEPFSIDETVTK--DNMPAALKTYLK 396
|
410 420
....*....|....*....|....*....
gi 489054606 399 HIEELIGAPVAMLSTSPEREDTILVTDPF 427
Cdd:PRK13784 397 TIENHVGIPISSLAYGPSREQILFFEDYF 425
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-421 |
1.88e-81 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 254.04 E-value: 1.88e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 1 MANVVVVGSQWGDEGKGKIVDWLS--ERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSV-IGNGVVVDPHH 77
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLaIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 78 FVAEVEKLRGQGidvtpdVLRVAENAPLILSIHRELDamREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEpetl 157
Cdd:PRK04293 81 LLKEVEELNVGG------RVFVDYRCGIIEEKHVEED--RSDEHLSKKIGSTGTGCGPANADRVLRRLKLAKDVEE---- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 158 rpkverllahhnslrrgmgLEEIavetilteLTSVADQILPYIDQvwrvlderrkaGARILFEGAQGALLDNDHGTYPFV 237
Cdd:PRK04293 149 -------------------LEKY--------LTDVPEEVNEALDR-----------GENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 238 TSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKghEFGVVTGRKRRCGWFDAVIVRQT 317
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRA 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 318 VRTSGINGIALTKLDVLDgleeiKICvayeldgkridylpssmgaqarvkpiyetlpgwsettAGARSWNDLPAQAVKYV 397
Cdd:PRK04293 269 ARINGATQIAITKLDKLD-----KEA-------------------------------------YGVTEYDKLPPEAKKFI 306
|
410 420
....*....|....*....|....
gi 489054606 398 RHIEELIGAPVAMLSTSPEREDTI 421
Cdd:PRK04293 307 EEIEEELGVPVTLISTGPELEDTI 330
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
3.29e-29 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 115.54 E-value: 3.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 5 VVVGSQWGDEGKGKIVDWLSERA--DVIVRyQGGHNAGHTlVID--GVSYKLSLLPSGLVRGKLS--VIGNGVVVDPHHF 78
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAapDVVVR-AAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPLKqvLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 79 VAEVEKLRGQGIDVTpDVLRVAENAPLI-LSIHREldamrEGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDltepetl 157
Cdd:NF038379 81 REEIEELEDAGHDVG-KRLLIHEQATVIeLHKHVE-----EEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGD------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 158 rpkverllaHHNSLRRGMGLEEIAVETILTELTSVADQILpyidqvwrvlderrKAGARILFEGAQGALLDNDHGTYPFV 237
Cdd:NF038379 148 ---------AEGDFGEGAVRDQPWEIAERVVDNALYDFAL--------------QAAERIQIEGTQGYSLGLHAGFYPYC 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 238 TSSNTVAGQAAAGSGLGPTAI--GYVLGITKAYTTRVGE-----GPFPTELNdeiGEFLGTKgHEFGVVTGRKRRCGWFD 310
Cdd:NF038379 205 TSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETT---WEELGLP-EELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 489054606 311 AVIVRQTVRTSG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-421 |
1.44e-20 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 94.35 E-value: 1.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 4 VVVVGSQWGDEGKGKIVDWLSER--ADVIVRYQGGHNAGHTlVID--GVSYKLSLLPSG-LVRGKLSVIGNGVVVDPHHF 78
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHT-VYDkaGRKFVFNLAPSGlLLPGKRNYIGPECVMDPVSF 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 79 V-AEVEKLRGQGIDVTpDVLRVAeNAPLILSIHRELDAMREGSNSglkigTTKRGIGPAYEDKVGRRAIRVIDL-TEPET 156
Cdd:PTZ00351 251 MeKEIIQLIDAGIDYR-DRLFIG-NVCIVTPYHKLLDLLGSAANS-----STLKGMAPVHGSKVMKRGIRLDHIfNDDET 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 157 LRPKVERLLAHHNSLRRGMGLEEIAVETILTELTS-----VADQILP--------------YIDQVWR---------VLD 208
Cdd:PTZ00351 324 LRKRLEKDMDTYLGLLKVKNLSDADVVRLCREENSdgvvrVPDYVIAfaqakdkveflvklYRDRVRHnpdfparcdVTY 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 209 ERRKA---GARILFEGAQGALLDNDHGTY-PFVTSSNTVAGQAAAGSGLGPTAI-GYVLGITKAY-TTRVGEG------- 275
Cdd:PTZ00351 404 ELHAAvlrGEKVLLEGPQSYWLSNARTKFwESTTSADTTAAGLLAASQLNFQKFkSVVLNVHKAPgSSRVGIGacpssfv 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 276 ------------------------------------PF------------PTELNDEIGEF-------LGTKGH--EFGV 298
Cdd:PTZ00351 484 pqdyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYnigvamaIASAQHhgECGA 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489054606 299 VTGRKRRCGWFDAVIVRQtvrTSGING--IALTKLDVLDGLEEIKICVA---YELDGKRIDY----------------LP 357
Cdd:PTZ00351 564 VTKKPRVCGFFDCVLQHE---VNSIQGpyLTISALDRGDEYDKVGVTIAyvyYNPEGKQVDVnghvykngdiiragdpVP 640
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489054606 358 SSmGAQARVKPIYETLPGWSETTAGA---RSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTI 421
Cdd:PTZ00351 641 SE-PALYHCHPIVKLIDGWRDNPIAAakrRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDII 706
|
|
| |
