NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|489056157|ref|WP_002966298|]
View 

MULTISPECIES: ABC transporter permease [Brucella]

Protein Classification

ABC transporter permease( domain architecture ID 11427288)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0022857|GO:0005524
PubMed:  35642569

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
7-254 1.49e-57

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 184.20  E-value: 1.49e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   7 FLAQLGIAVAVILVWHLFTATHLFGNpakaqFFFATPGDVALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIGF 86
Cdd:COG0600   12 LLLPLLSLALLLALWELAARLGLVPP-----FLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGVPLGL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  87 WFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNE 166
Cdd:COG0600   87 LLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASR 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 167 RQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDWGVSII 246
Cdd:COG0600  167 WQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLL 246

                 ....*...
gi 489056157 247 EQRLLVWR 254
Cdd:COG0600  247 ERRLLRWR 254
 
Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
7-254 1.49e-57

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 184.20  E-value: 1.49e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   7 FLAQLGIAVAVILVWHLFTATHLFGNpakaqFFFATPGDVALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIGF 86
Cdd:COG0600   12 LLLPLLSLALLLALWELAARLGLVPP-----FLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGVPLGL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  87 WFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNE 166
Cdd:COG0600   87 LLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASR 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 167 RQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDWGVSII 246
Cdd:COG0600  167 WQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLL 246

                 ....*...
gi 489056157 247 EQRLLVWR 254
Cdd:COG0600  247 ERRLLRWR 254
PRK10160 PRK10160
taurine ABC transporter permease TauC;
11-253 1.68e-18

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 82.53  E-value: 1.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  11 LGIAVAVILVWHLFTATHLFgnpakAQFFFATPGDV-----ALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIG 85
Cdd:PRK10160  28 IGTLAVLLAVWWAVAALQLI-----SPLFLPPPQQVlakllTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  86 FWFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMN 165
Cdd:PRK10160 103 IAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGAS 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 166 ERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIhQAEGVFDVTG-VFAGMLVLTAFVLLIDWGVS 244
Cdd:PRK10160 183 RAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMV-QSAGEFLATDvVLAGIAVIAIIAFLLELGLR 261

                 ....*....
gi 489056157 245 IIEQRLLVW 253
Cdd:PRK10160 262 ALQRRLTPW 270
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
81-252 5.68e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 62.70  E-value: 5.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   81 GVLIGFWFA--RKPLLAAIFDPYVKAANSLPRVVLAPIF-----ALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQ 153
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  154 TVLSNARMLGMNERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLT 233
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160
                         170       180
                  ....*....|....*....|...
gi 489056157  234 AFVLLI----DWGVSIIEQRLLV 252
Cdd:pfam00528 161 LILLLLnllvDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
63-240 1.37e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.66  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  63 LGITLLEAMLAFAIGAVGGVLIGFWFARK-PLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSK---------VALG 132
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 133 VSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYL 212
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                        170       180
                 ....*....|....*....|....*...
gi 489056157 213 IHQAEGVFDVTGVFAGMLVLTAFVLLID 240
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLL 188
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
57-250 1.10e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 42.53  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   57 GTIWYHLGITLLEAMLAFAIGAVGGVLIGFWFAR----KPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKV-AL 131
Cdd:TIGR01097  54 PRILKALLETLAMAILGTVLAAVLAVPLALLAARnitpSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVlAL 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  132 GVSLVFFIVFFnVYQGVKEVNQTVLSNARMLGMNERQLLRNVYLPSALSWMFSslhtavgfavVGAVVGEY-LGSSA--- 207
Cdd:TIGR01097 134 AFHTVGFLGKL-FAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLS----------YTLYRFEInVRAAAvlg 202
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 489056157  208 -----GLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDWGVSIIEQRL 250
Cdd:TIGR01097 203 lvgagGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLISARLRRRL 250
 
Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
7-254 1.49e-57

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 184.20  E-value: 1.49e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   7 FLAQLGIAVAVILVWHLFTATHLFGNpakaqFFFATPGDVALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIGF 86
Cdd:COG0600   12 LLLPLLSLALLLALWELAARLGLVPP-----FLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGVPLGL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  87 WFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNE 166
Cdd:COG0600   87 LLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASR 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 167 RQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDWGVSII 246
Cdd:COG0600  167 WQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLL 246

                 ....*...
gi 489056157 247 EQRLLVWR 254
Cdd:COG0600  247 ERRLLRWR 254
PRK10160 PRK10160
taurine ABC transporter permease TauC;
11-253 1.68e-18

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 82.53  E-value: 1.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  11 LGIAVAVILVWHLFTATHLFgnpakAQFFFATPGDV-----ALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIG 85
Cdd:PRK10160  28 IGTLAVLLAVWWAVAALQLI-----SPLFLPPPQQVlakllTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  86 FWFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMN 165
Cdd:PRK10160 103 IAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGAS 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 166 ERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIhQAEGVFDVTG-VFAGMLVLTAFVLLIDWGVS 244
Cdd:PRK10160 183 RAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMV-QSAGEFLATDvVLAGIAVIAIIAFLLELGLR 261

                 ....*....
gi 489056157 245 IIEQRLLVW 253
Cdd:PRK10160 262 ALQRRLTPW 270
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
2-255 2.30e-15

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 73.82  E-value: 2.30e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   2 KKPMLFLAQLGIAVAVILVWHLFTATHLFGNPakaqfFFATPGDVALRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGG 81
Cdd:PRK11365   6 KKWLLRVAPWFLPVGIVAVWQLASSVGWLSTR-----ILPSPEGVVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  82 VLIGFWFARKPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARM 161
Cdd:PRK11365  81 LILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 162 LGMNERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDW 241
Cdd:PRK11365 161 YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADV 240
                        250
                 ....*....|....
gi 489056157 242 GVSIIEQRLLVWRP 255
Cdd:PRK11365 241 SAQLLERLWLRWNP 254
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
81-252 5.68e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 62.70  E-value: 5.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   81 GVLIGFWFA--RKPLLAAIFDPYVKAANSLPRVVLAPIF-----ALWLGLGIWSKVALGVSLVFFIVFFNVYQGVKEVNQ 153
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  154 TVLSNARMLGMNERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYLIHQAEGVFDVTGVFAGMLVLT 233
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAA 160
                         170       180
                  ....*....|....*....|...
gi 489056157  234 AFVLLI----DWGVSIIEQRLLV 252
Cdd:pfam00528 161 LILLLLnllvDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
63-240 1.37e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.66  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  63 LGITLLEAMLAFAIGAVGGVLIGFWFARK-PLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSK---------VALG 132
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGilpglglpaLILA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 133 VSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNERQLLRNVYLPSALSWMFSSLHTAVGFAVVGAVVGEYLGSSAGLGYL 212
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                        170       180
                 ....*....|....*....|....*...
gi 489056157 213 IHQAEGVFDVTGVFAGMLVLTAFVLLID 240
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLL 188
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
57-250 1.10e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 42.53  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157   57 GTIWYHLGITLLEAMLAFAIGAVGGVLIGFWFAR----KPLLAAIFDPYVKAANSLPRVVLAPIFALWLGLGIWSKV-AL 131
Cdd:TIGR01097  54 PRILKALLETLAMAILGTVLAAVLAVPLALLAARnitpSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVlAL 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  132 GVSLVFFIVFFnVYQGVKEVNQTVLSNARMLGMNERQLLRNVYLPSALSWMFSslhtavgfavVGAVVGEY-LGSSA--- 207
Cdd:TIGR01097 134 AFHTVGFLGKL-FAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLS----------YTLYRFEInVRAAAvlg 202
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 489056157  208 -----GLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDWGVSIIEQRL 250
Cdd:TIGR01097 203 lvgagGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLISARLRRRL 250
COG4986 COG4986
ABC-type anion transport system, duplicated permease component [Inorganic ion transport and ...
48-255 3.90e-03

ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism];


Pssm-ID: 444010 [Multi-domain]  Cd Length: 576  Bit Score: 38.29  E-value: 3.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157  48 LRTYKWFVDGTIWYHLGITLLEAMLAFAIGAVGGVLIGFWFARKPLLAAIFDPYVKAANSLPRVVLAPIFALW-----LG 122
Cdd:COG4986  356 LTEVGLSEVLHVFLLGLLTLLRVVVLIALASLIWVPVGVWIGLRPRLARRLQPVAQFLASFPANLLFPVAVLLivrfgLN 435
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489056157 123 LGIWSkVALGVSLVFFIVFFNVYQGVKEVNQTVLSNARMLGMNERQLLRNVYLPS------------------------A 178
Cdd:COG4986  436 PNIWL-SPLMILGTQWYILFNVIAGASAIPNDLREAARNFGLRGWLWWRRLILPGifpyyvtgaitasggawnasivaeY 514
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489056157 179 LSWMFSSLHTavgfavvgavvgeylgssAGLGYLIHQAEGVFDVTGVFAGMLVLTAFVLLIDwgvsiieqrLLVWRP 255
Cdd:COG4986  515 VSWGDTTLQA------------------TGLGAYIAQATAAGDFPRILLGIAVMSLFVVLFN---------RLVWRP 564
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH