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Conserved domains on  [gi|489061612|ref|WP_002971643|]
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MULTISPECIES: GcrA family cell cycle regulator [Brucella]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5352 super family cl44222
Uncharacterized conserved protein [Function unknown];
8-58 2.03e-12

Uncharacterized conserved protein [Function unknown];


The actual alignment was detected with superfamily member COG5352:

Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 58.10  E-value: 2.03e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489061612   8 PHEGFRLADLSRRQCKWPVNRAQAGELHlFCGEAVQNGHPYCEEHCGKAYT 58
Cdd:COG5352  111 IAERLTLLELTERTCRWPIGDPGTPDFH-FCGAPVVPGKPYCAAHARIAYQ 160
 
Name Accession Description Interval E-value
COG5352 COG5352
Uncharacterized conserved protein [Function unknown];
8-58 2.03e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 58.10  E-value: 2.03e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489061612   8 PHEGFRLADLSRRQCKWPVNRAQAGELHlFCGEAVQNGHPYCEEHCGKAYT 58
Cdd:COG5352  111 IAERLTLLELTERTCRWPIGDPGTPDFH-FCGAPVVPGKPYCAAHARIAYQ 160
GcrA pfam07750
GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see ...
 14-64 3.62e-07

GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see pfam00072 and pfam00486), is involved in controlling cell cycle progression and asymmetric polar morphogenesis. During this process, there are temporal and spatial variations in the concentrations of GcrA and CtrA. The variation in concentration produces time and space dependent transcriptional regulation of modular functions that implement cell-cycle processes. More specifically, GcrA acts as an activator of components of the replisome and the segregation machinery.


Pssm-ID: 400210 [Multi-domain]  Cd Length: 155  Bit Score: 44.00  E-value: 3.62e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 489061612   14 LADLSRRQCKWPVNRAQAGELHlFCGEAVQNGHPYCEEHCGKAYTGKAGSR 64
Cdd:pfam07750 103 LLELGEATCRWPIGDPSNEEFH-FCGNKSSEGSSYCAPHSRLAYRPGAERR 152
 
Name Accession Description Interval E-value
COG5352 COG5352
Uncharacterized conserved protein [Function unknown];
8-58 2.03e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 58.10  E-value: 2.03e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489061612   8 PHEGFRLADLSRRQCKWPVNRAQAGELHlFCGEAVQNGHPYCEEHCGKAYT 58
Cdd:COG5352  111 IAERLTLLELTERTCRWPIGDPGTPDFH-FCGAPVVPGKPYCAAHARIAYQ 160
GcrA pfam07750
GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see ...
 14-64 3.62e-07

GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see pfam00072 and pfam00486), is involved in controlling cell cycle progression and asymmetric polar morphogenesis. During this process, there are temporal and spatial variations in the concentrations of GcrA and CtrA. The variation in concentration produces time and space dependent transcriptional regulation of modular functions that implement cell-cycle processes. More specifically, GcrA acts as an activator of components of the replisome and the segregation machinery.


Pssm-ID: 400210 [Multi-domain]  Cd Length: 155  Bit Score: 44.00  E-value: 3.62e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 489061612   14 LADLSRRQCKWPVNRAQAGELHlFCGEAVQNGHPYCEEHCGKAYTGKAGSR 64
Cdd:pfam07750 103 LLELGEATCRWPIGDPSNEEFH-FCGNKSSEGSSYCAPHSRLAYRPGAERR 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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