|
Name |
Accession |
Description |
Interval |
E-value |
| COG4646 |
COG4646 |
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]; |
910-2719 |
0e+00 |
|
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair];
Pssm-ID: 443684 [Multi-domain] Cd Length: 1711 Bit Score: 1081.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 910 EPFQATLLDYLKEKEEVELNEKEDRSSDEFAVKEDDTVYFNHEEYKVREISKNPITGRNDLWLDPARQGNHQIPIVAFTD 989
Cdd:COG4646 5 LDSESDEDRLRLEEEREERDERLEDLDAALVIKADEALEERGSEDDELGALSEDLASSLEDAELEDTELELLAILDGLPL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 990 NEDLLRQVSLERPDFIIGDEVKYKGKDYTITRFDDMGNNLKTVTIKDNTEYLGGMITGSDVIPYR-KESEIGKIFENLTY 1068
Cdd:COG4646 85 LEEELLAGRDALDDEAEEGEEVEGLSEGLKIAIELSRLGSELEAVLGAEAGDGLAAAIEAPIEIEnSEKLKAASTLLETV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1069 AKPEKTFEEAE---IKKNQAHNFKITEETLPSKLFPSERLNNNLEAISMLNRVESGERELDITAQEVLAKYVGWGGLADV 1145
Cdd:COG4646 165 TEPEVEAELAEvelLSAEAAAADEEVSSESLASTPAAARAGAAKILAVLLAEGALALKLARAAERLALAESGGERRNNAK 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1146 FDESKDGQWKEARAFLKEN------LSSSEYEAARESTLTSFYTPKTVIDGVYKTLSGMGFKQGNILEPSMGIGNFIGNL 1219
Cdd:COG4646 245 IEELALELDEELEADELANaaadaeLRDATKAAELATELDARARESDARAAGFRGGEGAILLEGGGLEGLAGGLIGEGGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1220 PdemnqskfYGVELDSVSGRIGKLLYPESDIQVKGLEETGFSNNFFDVAIGNVPFGEYKVNDREYNR--NNFLIHDYFFA 1297
Cdd:COG4646 325 G--------IGAEGAGSAGALTAALLNEQLAGAGGAIALLADPLAADLAFGLFPFLFVAANVFGGLKklFLADLHILFLS 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1298 KSIDKVRNGGVIAFITSSGTMDKKDESVRRYLAARTEFIGAIRLPNDTFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHL 1377
Cdd:COG4646 397 AAARLVRGRDALATLGSLKDAFPKARARRAARIAADLAASVAASLAAAARALATAEILEITEIREADRLEAEADEDLKDL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1378 AEDENGLS-------YNKYFVDHPEqvlgsmrevsgrfgktltcepiaylgteinmaslkerieiageriskeakyeeie 1450
Cdd:COG4646 477 EVVFAELEgegaiidVNRYFADHPE------------------------------------------------------- 501
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1451 llddeiTSIPATDDVKNFSYTLIDDEVYYRENSLFIKKEVSDKNKEKIKDYLELNAALKDVIYKQKEDfnEEEIKASQEK 1530
Cdd:COG4646 502 ------VTPPADPSVKDGSYTFEDGVLYVDEAHNFKNLEVPATKMRRVAGLIPLRDAVRELIEAQAED--DGSQKALRMR 573
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1531 LNEVYDNFSKKHGFVNNLSNTRALKEDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKIiDHVDTSLEALVLSVSEK 1610
Cdd:COG4646 574 LNCRYDAFVAKYGPINSRPNLRAFRDDPDYPLLLSLEEYDEETGTARKADIFTKRVIRPPTE-TSVDTAAEALAVSLNER 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1611 GYVDFDYMGSLTGKDRPTLIEELRGEIYLNIREeqnfyrplsfnledgdlpfacangsnsYKYGYVTKDEYLSGNIRDKI 1690
Cdd:COG4646 653 GRVDLDYMAELTGTPISNSLAELYGMIYLDPDT---------------------------LEDGWVTFDEYLSGNVREKL 705
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1691 VIVDSYLSKLRQTerelphlgYEENgkekelisyemnrleyqKTELTKVLPKELEASEINVRLGATWIPIKDIEKFIFET 1770
Cdd:COG4646 706 AAARAAAELDPRT--------FGEN-----------------VTALELVQPEDLEPSEIDVRLGATWIPKTRFEAFIREL 760
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1771 LKTPgyakwdIKVKFSNLTSEWNVEGKskdRGNDLAEMTFGTNRVNAYKLIEDALNLKETKVFDQIvnPDGSKtsVLNKK 1850
Cdd:COG4646 761 LGTP------ITVSYSPETGEWSVKGK---NGNAAATSTYGTERANAPELLEDALNVADIRIADPV--PDERR--VLNTE 827
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1851 ETMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTEIDLRPHQRNAIARSLYGGNTL 1930
Cdd:COG4646 828 ETEAAKEKQEAIKEAFAEWVWEDPERAERLVRLYNDKFNSIVPREYDGSHLKFPGDSRKISLRPHQKNAVARILYGGNTL 907
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1931 LAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYD 2010
Cdd:COG4646 908 LAHEVGAGKTFTMVAAAMELRRLGLANKPMIVVPNHLLEQDAPSKLNLYAAANILIATKTDFEKGTRLVFCADIATGDYD 987
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2011 AVVIGHTQFEKIPMSKEYQEKHIQDQIDEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDVITFEELG 2090
Cdd:COG4646 988 AVIIGHIQFEKIPASGERQEEILEEQIAEILKAIKELKAVVRKRFTVKQLESTKKLGAGKLKQLDLLALKDLDVPWEPLD 1067
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2091 VDKLFVDEAHGFKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGGKGVVFATGTPVSNSMTELYTMQRYLQYES 2170
Cdd:COG4646 1068 VDQLFGRGSRQGNNNFLVTKMRNVAGLAFSDAAKLSDYFGKQRYRDELTAGKGVVVATGTDESNLMYELYTAQAYLQLLL 1147
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2171 LKKNNLEHFDSWASTFGETQSSFELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPS 2250
Cdd:COG4646 1148 LGKQGLTNFDTWASTLEELVTAAELAPERTAYRANTREAKAVNLPEEDVMIKEAEDAKTADELLLPTPEKISGGVATKPS 1227
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2251 EEQKEILKSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNVFAIWDKTKENRSTQL 2330
Cdd:COG4646 1228 EVQKELLEELEERAAIVRKNDGEPDRDNMLVITDDGRKAALDQRLDIKTLPDDEGSLVALCVTNIDRIWEDNPESKLTQL 1307
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2331 LFSDMSTPKGDGEFNIYDDIREKLVSMGIPKEEIAFIHEANSDKQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIA 2410
Cdd:COG4646 1308 VFCDLSTPKGDGTFNDLEDIREKLIEEEIAELEIAFIHLALDDQEKAELFARDRLGAVEKLRISTAKMGAGTNVRLLLEA 1387
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2411 MHDLDVPWRPADLEQRAGRIVRQGNENEKVNIYRYVTENTFDSYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNYA 2490
Cdd:COG4646 1388 THDLDVPWRPRDAEQRAGRGRRQGNENEEVEEIRYVTENTFDAYLWQAAETKQKFIAQIMTSKSPVRSLEDVDEAALSYA 1467
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2491 EIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKLIEAVKKDIASVEPKAEGEEKFTS 2570
Cdd:COG4646 1468 ERKALAAGRPKEKEKMDLDIEVLKLKLLDAAALEQLYAEEDKLRKSYLDEEEALEERIEAATKDLRLARAASQEEADEQE 1547
|
1690 1700 1710 1720 1730 1740 1750 1760
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2571 ITIAGEKITDKKLAGERLLEAISKVKINESKVIGRYRNMDLEVSYNFFTNEHNFSLNGAAKHSGELGTSVDGNITRLDNA 2650
Cdd:COG4646 1548 SASKEAAAGEKKAAAAELLAALQAAGLIVLDGGRTPRGEKGGGLLARALLEAATLLLPIEEAEGSEGADATGDRRTGAAA 1627
|
1770 1780 1790 1800 1810 1820
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489079422 2651 LEKMPEKLNRLEEKLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKRNDNPLVE 2719
Cdd:COG4646 1628 EIELAAEALILNLAERLERALRDGAEEEEIAPRELEAALKEEAALLARAGELAELELDKADLEAELEAL 1696
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
1912-2013 |
1.05e-08 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 57.89 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1912 LRPHQRNAIARSLYG-GNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPN-HLTGQIGREFMQLYPSANIMVADK 1989
Cdd:smart00487 9 LRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTrELAEQWAEELKKLGPSLGLKVVGL 88
|
90 100
....*....|....*....|....
gi 489079422 1990 kdFEPKNRKRFIGKIATGEYDAVV 2013
Cdd:smart00487 89 --YGGDSKREQLRKLESGKTDILV 110
|
|
| DEXDc_RapA |
cd18011 |
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated ... |
1912-2067 |
1.48e-06 |
|
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350769 [Multi-domain] Cd Length: 207 Bit Score: 51.52 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1912 LRPHQRNAIARSLYGGNT--LLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQ----IGREFMQlypsaNIM 1985
Cdd:cd18011 1 PLPHQIDAVLRALRKPPVrlLLADEVGLGKTIEAGLIIKELLLRGDAKRVLILCPASLVEQwqdeLQDKFGL-----PFL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1986 VADKKDFEpknRKRFIGKIATGEYDaVVIGHTQFEKipmSKEYQEKHIQDQ------IDEIVNYVEEYKHDRNQNF-TVK 2058
Cdd:cd18011 76 ILDRETAA---QLRRLIGNPFEEFP-IVIVSLDLLK---RSEERRGLLLSEewdlvvVDEAHKLRNSGGGKETKRYkLGR 148
|
170
....*....|
gi 489079422 2059 QL-EKTKKKL 2067
Cdd:cd18011 149 LLaKRARHVL 158
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
2363-2434 |
6.74e-06 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 47.21 E-value: 6.74e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489079422 2363 EIAFIHEANSDKQKDELFAKVRKGEVRILMgSTQKMGAGTNVQNkLIAMHDLDVPWRPADLEQRAGRIVRQG 2434
Cdd:pfam00271 40 KVARLHGDLSQEEREEILEDFRKGKIDVLV-ATDVAERGLDLPD-VDLVINYDLPWNPASYIQRIGRAGRAG 109
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG4646 |
COG4646 |
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]; |
910-2719 |
0e+00 |
|
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair];
Pssm-ID: 443684 [Multi-domain] Cd Length: 1711 Bit Score: 1081.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 910 EPFQATLLDYLKEKEEVELNEKEDRSSDEFAVKEDDTVYFNHEEYKVREISKNPITGRNDLWLDPARQGNHQIPIVAFTD 989
Cdd:COG4646 5 LDSESDEDRLRLEEEREERDERLEDLDAALVIKADEALEERGSEDDELGALSEDLASSLEDAELEDTELELLAILDGLPL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 990 NEDLLRQVSLERPDFIIGDEVKYKGKDYTITRFDDMGNNLKTVTIKDNTEYLGGMITGSDVIPYR-KESEIGKIFENLTY 1068
Cdd:COG4646 85 LEEELLAGRDALDDEAEEGEEVEGLSEGLKIAIELSRLGSELEAVLGAEAGDGLAAAIEAPIEIEnSEKLKAASTLLETV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1069 AKPEKTFEEAE---IKKNQAHNFKITEETLPSKLFPSERLNNNLEAISMLNRVESGERELDITAQEVLAKYVGWGGLADV 1145
Cdd:COG4646 165 TEPEVEAELAEvelLSAEAAAADEEVSSESLASTPAAARAGAAKILAVLLAEGALALKLARAAERLALAESGGERRNNAK 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1146 FDESKDGQWKEARAFLKEN------LSSSEYEAARESTLTSFYTPKTVIDGVYKTLSGMGFKQGNILEPSMGIGNFIGNL 1219
Cdd:COG4646 245 IEELALELDEELEADELANaaadaeLRDATKAAELATELDARARESDARAAGFRGGEGAILLEGGGLEGLAGGLIGEGGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1220 PdemnqskfYGVELDSVSGRIGKLLYPESDIQVKGLEETGFSNNFFDVAIGNVPFGEYKVNDREYNR--NNFLIHDYFFA 1297
Cdd:COG4646 325 G--------IGAEGAGSAGALTAALLNEQLAGAGGAIALLADPLAADLAFGLFPFLFVAANVFGGLKklFLADLHILFLS 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1298 KSIDKVRNGGVIAFITSSGTMDKKDESVRRYLAARTEFIGAIRLPNDTFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHL 1377
Cdd:COG4646 397 AAARLVRGRDALATLGSLKDAFPKARARRAARIAADLAASVAASLAAAARALATAEILEITEIREADRLEAEADEDLKDL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1378 AEDENGLS-------YNKYFVDHPEqvlgsmrevsgrfgktltcepiaylgteinmaslkerieiageriskeakyeeie 1450
Cdd:COG4646 477 EVVFAELEgegaiidVNRYFADHPE------------------------------------------------------- 501
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1451 llddeiTSIPATDDVKNFSYTLIDDEVYYRENSLFIKKEVSDKNKEKIKDYLELNAALKDVIYKQKEDfnEEEIKASQEK 1530
Cdd:COG4646 502 ------VTPPADPSVKDGSYTFEDGVLYVDEAHNFKNLEVPATKMRRVAGLIPLRDAVRELIEAQAED--DGSQKALRMR 573
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1531 LNEVYDNFSKKHGFVNNLSNTRALKEDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKIiDHVDTSLEALVLSVSEK 1610
Cdd:COG4646 574 LNCRYDAFVAKYGPINSRPNLRAFRDDPDYPLLLSLEEYDEETGTARKADIFTKRVIRPPTE-TSVDTAAEALAVSLNER 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1611 GYVDFDYMGSLTGKDRPTLIEELRGEIYLNIREeqnfyrplsfnledgdlpfacangsnsYKYGYVTKDEYLSGNIRDKI 1690
Cdd:COG4646 653 GRVDLDYMAELTGTPISNSLAELYGMIYLDPDT---------------------------LEDGWVTFDEYLSGNVREKL 705
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1691 VIVDSYLSKLRQTerelphlgYEENgkekelisyemnrleyqKTELTKVLPKELEASEINVRLGATWIPIKDIEKFIFET 1770
Cdd:COG4646 706 AAARAAAELDPRT--------FGEN-----------------VTALELVQPEDLEPSEIDVRLGATWIPKTRFEAFIREL 760
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1771 LKTPgyakwdIKVKFSNLTSEWNVEGKskdRGNDLAEMTFGTNRVNAYKLIEDALNLKETKVFDQIvnPDGSKtsVLNKK 1850
Cdd:COG4646 761 LGTP------ITVSYSPETGEWSVKGK---NGNAAATSTYGTERANAPELLEDALNVADIRIADPV--PDERR--VLNTE 827
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1851 ETMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTEIDLRPHQRNAIARSLYGGNTL 1930
Cdd:COG4646 828 ETEAAKEKQEAIKEAFAEWVWEDPERAERLVRLYNDKFNSIVPREYDGSHLKFPGDSRKISLRPHQKNAVARILYGGNTL 907
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1931 LAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYD 2010
Cdd:COG4646 908 LAHEVGAGKTFTMVAAAMELRRLGLANKPMIVVPNHLLEQDAPSKLNLYAAANILIATKTDFEKGTRLVFCADIATGDYD 987
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2011 AVVIGHTQFEKIPMSKEYQEKHIQDQIDEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDVITFEELG 2090
Cdd:COG4646 988 AVIIGHIQFEKIPASGERQEEILEEQIAEILKAIKELKAVVRKRFTVKQLESTKKLGAGKLKQLDLLALKDLDVPWEPLD 1067
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2091 VDKLFVDEAHGFKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGGKGVVFATGTPVSNSMTELYTMQRYLQYES 2170
Cdd:COG4646 1068 VDQLFGRGSRQGNNNFLVTKMRNVAGLAFSDAAKLSDYFGKQRYRDELTAGKGVVVATGTDESNLMYELYTAQAYLQLLL 1147
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2171 LKKNNLEHFDSWASTFGETQSSFELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPS 2250
Cdd:COG4646 1148 LGKQGLTNFDTWASTLEELVTAAELAPERTAYRANTREAKAVNLPEEDVMIKEAEDAKTADELLLPTPEKISGGVATKPS 1227
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2251 EEQKEILKSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNVFAIWDKTKENRSTQL 2330
Cdd:COG4646 1228 EVQKELLEELEERAAIVRKNDGEPDRDNMLVITDDGRKAALDQRLDIKTLPDDEGSLVALCVTNIDRIWEDNPESKLTQL 1307
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2331 LFSDMSTPKGDGEFNIYDDIREKLVSMGIPKEEIAFIHEANSDKQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIA 2410
Cdd:COG4646 1308 VFCDLSTPKGDGTFNDLEDIREKLIEEEIAELEIAFIHLALDDQEKAELFARDRLGAVEKLRISTAKMGAGTNVRLLLEA 1387
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2411 MHDLDVPWRPADLEQRAGRIVRQGNENEKVNIYRYVTENTFDSYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNYA 2490
Cdd:COG4646 1388 THDLDVPWRPRDAEQRAGRGRRQGNENEEVEEIRYVTENTFDAYLWQAAETKQKFIAQIMTSKSPVRSLEDVDEAALSYA 1467
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2491 EIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKLIEAVKKDIASVEPKAEGEEKFTS 2570
Cdd:COG4646 1468 ERKALAAGRPKEKEKMDLDIEVLKLKLLDAAALEQLYAEEDKLRKSYLDEEEALEERIEAATKDLRLARAASQEEADEQE 1547
|
1690 1700 1710 1720 1730 1740 1750 1760
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2571 ITIAGEKITDKKLAGERLLEAISKVKINESKVIGRYRNMDLEVSYNFFTNEHNFSLNGAAKHSGELGTSVDGNITRLDNA 2650
Cdd:COG4646 1548 SASKEAAAGEKKAAAAELLAALQAAGLIVLDGGRTPRGEKGGGLLARALLEAATLLLPIEEAEGSEGADATGDRRTGAAA 1627
|
1770 1780 1790 1800 1810 1820
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489079422 2651 LEKMPEKLNRLEEKLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKRNDNPLVE 2719
Cdd:COG4646 1628 EIELAAEALILNLAERLERALRDGAEEEEIAPRELEAALKEEAALLARAGELAELELDKADLEAELEAL 1696
|
|
| COG4646 |
COG4646 |
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]; |
1562-2915 |
1.12e-127 |
|
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair];
Pssm-ID: 443684 [Multi-domain] Cd Length: 1711 Bit Score: 445.85 E-value: 1.12e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1562 LVSSIEILDEEENFKAKGDIFSKRTITKAKIIDHVDTSLEALVLSVSEKGYVDFDYMGSLTGKDRPTLIEELRGEIYLNI 1641
Cdd:COG4646 18 EEREERDERLEDLDAALVIKADEALEERGSEDDELGALSEDLASSLEDAELEDTELELLAILDGLPLLEEELLAGRDALD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1642 REEQNFYRPLSFNLEDGDLPFACANGSNSYKYGYVTKDEYLSGNIRDKIVIVDSYLSKLRQTERELPHlgyeengkekel 1721
Cdd:COG4646 98 DEAEEGEEVEGLSEGLKIAIELSRLGSELEAVLGAEAGDGLAAAIEAPIEIENSEKLKAASTLLETVT------------ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1722 isyemnrleyqkteltkvlPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGYAKWDIKVKFSNLTSEWNVEGKSKDR 1801
Cdd:COG4646 166 -------------------EPEVEAELAEVELLSAEAAAADEEVSSESLASTPAAARAGAAKILAVLLAEGALALKLARA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1802 GNDLAEMTFGTNRVNAYKLIEDALNLKETKVFDQIVNPDGSKTSVLNKKETMLAGQKQELLKEEFKNWIFNDQERRNRLV 1881
Cdd:COG4646 227 AERLALAESGGERRNNAKIEELALELDEELEADELANAAADAELRDATKAAELATELDARARESDARAAGFRGGEGAILL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1882 KLYNERFNSIRNREYDGSNLSFEGMNTEIDLRPHQRNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLF 1961
Cdd:COG4646 307 EGGGLEGLAGGLIGEGGLGIGAEGAGSAGALTAALLNEQLAGAGGAIALLADPLAADLAFGLFPFLFVAANVFGGLKKLF 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1962 VVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGHTQFEKIPMSKEYQEKHIQDQIDEIV 2041
Cdd:COG4646 387 LADLHILFLSAAARLVRGRDALATLGSLKDAFPKARARRAARIAADLAASVAASLAAAARALATAEILEITEIREADRLE 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2042 NYVEEYKHDRNQNFTVKQLEKTKKKLET------RLEKLNDDFKKDDVITFEElgvDKLFVDEAHGFKNLYL-YTKMRNV 2114
Cdd:COG4646 467 AEADEDLKDLEVVFAELEGEGAIIDVNRyfadhpEVTPPADPSVKDGSYTFED---GVLYVDEAHNFKNLEVpATKMRRV 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2115 AGIGQ---------------SEAFKSSDMFMKCRY------------------------------MDEMTGG-----KGV 2144
Cdd:COG4646 544 AGLIPlrdavrelieaqaedDGSQKALRMRLNCRYdafvakygpinsrpnlrafrddpdyplllsLEEYDEEtgtarKAD 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2145 VF-------------------------------------ATGTPVSNSMTELYTMqRYLQYESLKkNNLEHFDSWAS--- 2184
Cdd:COG4646 624 IFtkrvirpptetsvdtaaealavslnergrvdldymaeLTGTPISNSLAELYGM-IYLDPDTLE-DGWVTFDEYLSgnv 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2185 ----------------TFGETQSSFE------LSPE------GTGYRVKTRFSKFY------------------------ 2212
Cdd:COG4646 702 reklaaaraaaeldprTFGENVTALElvqpedLEPSeidvrlGATWIPKTRFEAFIrellgtpitvsyspetgewsvkgk 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2213 ---------------NLPELMSMFKEVADIQTADmlnlPTPEAnYEVIKTEPSEEQKEILKSL-----------SERAD- 2265
Cdd:COG4646 782 ngnaaatstygteraNAPELLEDALNVADIRIAD----PVPDE-RRVLNTEETEAAKEKQEAIkeafaewvwedPERAEr 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2266 --DVRNR----VVEPDVD-NMLKITNDGKK------------------------------------LALDQRLINP---- 2298
Cdd:COG4646 857 lvRLYNDkfnsIVPREYDgSHLKFPGDSRKislrphqknavarilyggntllahevgagktftmvaAAMELRRLGLankp 936
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2299 -------LLPDNPDSKVNVCVKNVFAIWDKTKENRSTQLLFSDMSTPKGDGEFNIYDDIREKLVSMGIPKEEIAFIHEAN 2371
Cdd:COG4646 937 mivvpnhLLEQDAPSKLNLYAAANILIATKTDFEKGTRLVFCADIATGDYDAVIIGHIQFEKIPASGERQEEILEEQIAE 1016
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2372 SDKQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIAMHDLDVPWRPADLEQRAGRIVRQGNENEKVNIYRYVTENTF 2451
Cdd:COG4646 1017 ILKAIKELKAVVRKRFTVKQLESTKKLGAGKLKQLDLLALKDLDVPWEPLDVDQLFGRGSRQGNNNFLVTKMRNVAGLAF 1096
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2452 DSYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNYAEIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLED 2531
Cdd:COG4646 1097 SDAAKLSDYFGKQRYRDELTAGKGVVVATGTDESNLMYELYTAQAYLQLLLLGKQGLTNFDTWASTLEELVTAAELAPER 1176
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2532 KVAKNYPEEIARTEKLIEAVKKDIASVEPKAEGEEKFTSITIAGEKITDKKLAGERLLEAISKVKINESKVIGRYRNMDL 2611
Cdd:COG4646 1177 TAYRANTREAKAVNLPEEDVMIKEAEDAKTADELLLPTPEKISGGVATKPSEVQKELLEELEERAAIVRKNDGEPDRDNM 1256
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2612 EVSYNFFTNEHNFSLNGAAKHSGELGTSVDGNITRLDNALEKMPEKLNRLEEKLISTKEQLENAKEELKKPFEKADELKT 2691
Cdd:COG4646 1257 LVITDDGRKAALDQRLDIKTLPDDEGSLVALCVTNIDRIWEDNPESKLTQLVFCDLSTPKGDGTFNDLEDIREKLIEEEI 1336
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2692 KVLRLAELNKLLDMGEVEEKRNDNPLVEDVKRAIIDFCNREYEENHSYDEFNTLYPDLKHIGIAYTNTPDERHGIQYELN 2771
Cdd:COG4646 1337 AELEIAFIHLALDDQEKAELFARDRLGAVEKLRISTAKMGAGTNVRLLLEATHDLDVPWRPRDAEQRAGRGRRQGNENEE 1416
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2772 LEEKTWTQYIDDTPIKTESFDYESKGENEALRNMKNEMEMSSFSDLVYVDSEDLKAATGLEIDDEGNFYDPLSKDLDNDG 2851
Cdd:COG4646 1417 VEEIRYVTENTFDAYLWQAAETKQKFIAQIMTSKSPVRSLEDVDEAALSYAERKALAAGRPKEKEKMDLDIEVLKLKLLD 1496
|
1530 1540 1550 1560 1570 1580
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489079422 2852 IPDRYDNDFKDSDYFESTYDVEDNLHSKEETAQKSEDKPSILGQIRAYQNESKTEEKQKTKEQE 2915
Cdd:COG4646 1497 AAALEQLYAEEDKLRKSYLDEEEALEERIEAATKDLRLARAASQEEADEQESASKEAAAGEKKA 1560
|
|
| YtxK |
COG0827 |
Adenine-specific DNA N6-methylase [Replication, recombination and repair]; |
1109-1365 |
1.57e-25 |
|
Adenine-specific DNA N6-methylase [Replication, recombination and repair];
Pssm-ID: 440589 [Multi-domain] Cd Length: 327 Bit Score: 110.42 E-value: 1.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1109 LEA-ISMLNRVESGERELDITAQEVLAKYVGWGGLAdvFDESKDGQWKEAraflkenLSSSEYEAARESTLTSF-YTPKT 1186
Cdd:COG0827 29 LEAlIETLENLLDGEVEGKPTEEAKKKLKKNYQKLQ--LESLSKEEIRKA-------LQLALLKGMKESVQPNHqMTPDA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1187 VIDGVYKTLSGMG-FKQGNILEPSMGIGNFIGNLPDEM-NQSKFYGVELDSVSGRIGKLLYPESDIQVKGLEETGFSNNF 1264
Cdd:COG0827 100 IGLLIGYLVEKFTkKEGLRILDPAVGTGNLLTTVLNQLkKKVNAYGVEVDDLLIRLAAVLANLQGHPVELFHQDALQPLL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1265 ---FDVAIGNVPFGEYKVNDREYN------RNNFLIHDYFFAKSIDKVRNGGVIAFITSSGTMDKKD-ESVRRYLAARTE 1334
Cdd:COG0827 180 idpVDVVISDLPVGYYPNDERAKRfklkadEGHSYAHHLFIEQSLNYLKPGGYLFFLVPSNLFESDQaAQLREFLKEKAH 259
|
250 260 270
....*....|....*....|....*....|.
gi 489079422 1335 FIGAIRLPNDTFKGVAGTEvtsDIIFLKKRD 1365
Cdd:COG0827 260 IQGLIQLPESLFKNEAAAK---SILILQKKG 287
|
|
| HepA |
COG0553 |
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, ... |
1911-2470 |
5.08e-20 |
|
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, and repair];
Pssm-ID: 440319 [Multi-domain] Cd Length: 682 Bit Score: 97.60 E-value: 5.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1911 DLRPHQRNAIAR----SLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQIGREFMQLYPSANIMV 1986
Cdd:COG0553 241 TLRPYQLEGAAWllflRRLGLGGLLADDMGLGKTIQALALLLELKERGLARPVLIVAPTSLVGNWQRELAKFAPGLRVLV 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1987 ADKKDFEPKNRKRFigkiatGEYDAVvightqfekipmskeyqekhiqdqideIVNYveeykhdrnqnftvkqlektkkk 2066
Cdd:COG0553 321 LDGTRERAKGANPF------EDADLV---------------------------ITSY----------------------- 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2067 letrleklndDFKKDDVITFEELGVDKLFVDEAHGFKNlylytkmrnvAGIGQSEAFKSsdmfMKCRYmdemtggkgVVF 2146
Cdd:COG0553 345 ----------GLLRRDIELLAAVDWDLVILDEAQHIKN----------PATKRAKAVRA----LKARH---------RLA 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2147 ATGTPVSNSMTELYTMQRYLqyeslkknNLEHFDSWAStFGETqssFELSPEGTGYRvktrfskfyNLPELMSMFKEV-- 2224
Cdd:COG0553 392 LTGTPVENRLEELWSLLDFL--------NPGLLGSLKA-FRER---FARPIEKGDEE---------ALERLRRLLRPFll 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2225 ----ADIQTadmlNLPtpEANYEVIKTEPSEEQKEILKSLSERADDvrnrvvepDVDNMLKITNDGKKLALDQRL----I 2296
Cdd:COG0553 451 rrtkEDVLK----DLP--EKTEETLYVELTPEQRALYEAVLEYLRR--------ELEGAEGIRRRGLILAALTRLrqicS 516
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2297 NP--LLPD-----NPDSKVNVCVKnvfaIWDKTKENRSTQLLFSdmstpkgdgEFNIY-DDIREKLVSMGIPkeeIAFIH 2368
Cdd:COG0553 517 HPalLLEEgaelsGRSAKLEALLE----LLEELLAEGEKVLVFS---------QFTDTlDLLEERLEERGIE---YAYLH 580
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2369 EANSDKQKDELFAKVRKG-EVRILMGSTQKMGAGTNVQ--NKLIamHdLDVPWRPADLEQRAGRIVRQGNENeKVNIYRY 2445
Cdd:COG0553 581 GGTSAEERDELVDRFQEGpEAPVFLISLKAGGEGLNLTaaDHVI--H-YDLWWNPAVEEQAIDRAHRIGQTR-DVQVYKL 656
|
570 580
....*....|....*....|....*
gi 489079422 2446 VTENTFDSYLWQTIENKQKFISQIM 2470
Cdd:COG0553 657 VAEGTIEEKILELLEEKRALAESVL 681
|
|
| HsdM |
COG0286 |
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms]; |
1181-1366 |
1.04e-12 |
|
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms];
Pssm-ID: 440055 [Multi-domain] Cd Length: 243 Bit Score: 70.60 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1181 FYTPKTVIdgvyKTLSGMGFKQGN--ILEPSMGIGNF--------IGNLPDEMNQSKFYGVELDSVSGRIGKL-LY---- 1245
Cdd:COG0286 25 FYTPREVV----RLMVELLDPKPGetVYDPACGSGGFlveaaeylKEHGGDERKKLSLYGQEINPTTYRLAKMnLLlhgi 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1246 PESDIQVKG-LEETGFSNNFFDVAIGNVPFG----EYKVNDREYNRNNFLIH-----DY-FFAKSIDKVRNGGVIAFITS 1314
Cdd:COG0286 101 GDPNIELGDtLSNDGDELEKFDVVLANPPFGgkwkKEELKDDLLGRFGYGLPpksnaDLlFLQHILSLLKPGGRAAVVLP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 489079422 1315 SGTMDKKDES-VRRYLAARTEFIGAIRLPNDTFKGvAGTEVTsdIIFLKKRDS 1366
Cdd:COG0286 181 DGVLFRGAEKeIRKKLLENDLLEAIIGLPSNLFYN-TGIPTC--ILFLTKGKP 230
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
1912-2013 |
1.05e-08 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 57.89 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1912 LRPHQRNAIARSLYG-GNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPN-HLTGQIGREFMQLYPSANIMVADK 1989
Cdd:smart00487 9 LRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTrELAEQWAEELKKLGPSLGLKVVGL 88
|
90 100
....*....|....*....|....
gi 489079422 1990 kdFEPKNRKRFIGKIATGEYDAVV 2013
Cdd:smart00487 89 --YGGDSKREQLRKLESGKTDILV 110
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
2348-2434 |
2.43e-08 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 53.37 E-value: 2.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2348 DDIREKLVSMGIPkeeIAFIHEANSDKQKDELFAKVRKGEVRILMgSTQKMGAGTNVQNKLIaMHDLDVPWRPADLEQRA 2427
Cdd:smart00490 1 EELAELLKELGIK---VARLHGGLSQEEREEILDKFNNGKIKVLV-ATDVAERGLDLPGVDL-VIIYDLPWSPASYIQRI 75
|
....*..
gi 489079422 2428 GRIVRQG 2434
Cdd:smart00490 76 GRAGRAG 82
|
|
| DEXDc_RapA |
cd18011 |
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated ... |
1912-2067 |
1.48e-06 |
|
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350769 [Multi-domain] Cd Length: 207 Bit Score: 51.52 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1912 LRPHQRNAIARSLYGGNT--LLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQ----IGREFMQlypsaNIM 1985
Cdd:cd18011 1 PLPHQIDAVLRALRKPPVrlLLADEVGLGKTIEAGLIIKELLLRGDAKRVLILCPASLVEQwqdeLQDKFGL-----PFL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1986 VADKKDFEpknRKRFIGKIATGEYDaVVIGHTQFEKipmSKEYQEKHIQDQ------IDEIVNYVEEYKHDRNQNF-TVK 2058
Cdd:cd18011 76 ILDRETAA---QLRRLIGNPFEEFP-IVIVSLDLLK---RSEERRGLLLSEewdlvvVDEAHKLRNSGGGKETKRYkLGR 148
|
170
....*....|
gi 489079422 2059 QL-EKTKKKL 2067
Cdd:cd18011 149 LLaKRARHVL 158
|
|
| SF2_C_SNF |
cd18793 |
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ... |
2348-2446 |
4.71e-06 |
|
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350180 [Multi-domain] Cd Length: 135 Bit Score: 48.24 E-value: 4.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2348 DDIREKLVSMGIpkeEIAFIHEANSDKQKDELFAKVRKG-EVRILMGSTQKMGAGTNVQ--NKLIAMhdlDVPWRPADLE 2424
Cdd:cd18793 41 DILEEALRERGI---KYLRLDGSTSSKERQKLVDRFNEDpDIRVFLLSTKAGGVGLNLTaaNRVILY---DPWWNPAVEE 114
|
90 100
....*....|....*....|..
gi 489079422 2425 QRAGRIVRQGNENEkVNIYRYV 2446
Cdd:cd18793 115 QAIDRAHRIGQKKP-VVVYRLI 135
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
2363-2434 |
6.74e-06 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 47.21 E-value: 6.74e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489079422 2363 EIAFIHEANSDKQKDELFAKVRKGEVRILMgSTQKMGAGTNVQNkLIAMHDLDVPWRPADLEQRAGRIVRQG 2434
Cdd:pfam00271 40 KVARLHGDLSQEEREEILEDFRKGKIDVLV-ATDVAERGLDLPD-VDLVINYDLPWNPASYIQRIGRAGRAG 109
|
|
| ResIII |
pfam04851 |
Type III restriction enzyme, res subunit; |
1909-2006 |
3.15e-05 |
|
Type III restriction enzyme, res subunit;
Pssm-ID: 398492 [Multi-domain] Cd Length: 162 Bit Score: 46.90 E-value: 3.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1909 EIDLRPHQRNAIARSLYG-----GNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVP-NHLTGQIGREFMQLYPSA 1982
Cdd:pfam04851 1 KLELRPYQIEAIENLLESikngqKRGLIVMATGSGKTLTAAKLIARLFKKGPIKKVLFLVPrKDLLEQALEEFKKFLPNY 80
|
90 100
....*....|....*....|....*...
gi 489079422 1983 ----NIMVADKKDFEPKNRKRFIGKIAT 2006
Cdd:pfam04851 81 veigEIISGDKKDESVDDNKIVVTTIQS 108
|
|
| DEXDc_SHPRH-like |
cd18008 |
DEXH-box helicase domain of SHPRH-like proteins; The SHPRH-like subgroup belongs to the ... |
1912-2211 |
3.55e-05 |
|
DEXH-box helicase domain of SHPRH-like proteins; The SHPRH-like subgroup belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350766 [Multi-domain] Cd Length: 241 Bit Score: 48.05 E-value: 3.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1912 LRPHQRNAIARSL-YGGntLLAHVVGSGKTFEMVA------------------SAMESKRLGMCSKSLFVVPNHLTGQIG 1972
Cdd:cd18008 1 LLPYQKQGLAWMLpRGG--ILADEMGLGKTIQALAlilatrpqdpkipeeleeNSSDPKKLYLSKTTLIVVPLSLLSQWK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1973 REFMQ--LYPSANIMVADKKDfepknRKRFIGKIAtgEYDAVVIGHTQFEKipmskeyqekhiqdqideivnyveEYKhD 2050
Cdd:cd18008 79 DEIEKhtKPGSLKVYVYHGSK-----RIKSIEELS--DYDIVITTYGTLAS------------------------EFP-K 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2051 RNQNFTVKQLEKTKKKLetrlekLNDDFKKddVItfeelgvdklfVDEAHGFKNlylytkmrnvagigqseafKSSDMFM 2130
Cdd:cd18008 127 NKKGGGRDSKEKEASPL------HRIRWYR--VI-----------LDEAHNIKN-------------------RSTKTSR 168
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 2131 KCRYMDemtggkgvvfA------TGTPVSNSMTELYTMQRYLQyeslkknnLEHFDSWASTFGETQSSFELSPEGTGYRV 2204
Cdd:cd18008 169 AVCALK----------AerrwclTGTPIQNSLDDLYSLLRFLR--------VEPFGDYPWFNSDISKPFSKNDRKALERL 230
|
....*..
gi 489079422 2205 KTRFSKF 2211
Cdd:cd18008 231 QALLKPI 237
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
1912-1986 |
8.25e-04 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 42.29 E-value: 8.25e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489079422 1912 LRPHQRNAIARSLYGGNT---LLAHVVGSGKTFEMVASAMESKRLgmcsKSLFVVP-NHLTGQIGREFMQLYPSANIMV 1986
Cdd:cd17926 1 LRPYQEEALEAWLAHKNNrrgILVLPTGSGKTLTALALIAYLKEL----RTLIVVPtDALLDQWKERFEDFLGDSSIGL 75
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
1860-1993 |
8.94e-04 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 44.63 E-value: 8.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1860 ELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGM-------NTEIDLRPHQRNAIARSLY-----GG 1927
Cdd:COG1061 22 DLERLELSLLRNLVEARRLAIKEGTREDGRRLPEEDTERELAEAEALeagdeasGTSFELRPYQQEALEALLAalergGG 101
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489079422 1928 NTLLAHVVGSGKTFemVASAMeSKRLGMCSKSLFVVPN-HLTGQIGREFMQLYPSANImVADKKDFE 1993
Cdd:COG1061 102 RGLVVAPTGTGKTV--LALAL-AAELLRGKRVLVLVPRrELLEQWAEELRRFLGDPLA-GGGKKDSD 164
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
1926-2041 |
2.49e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 40.85 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079422 1926 GGNTLLAHVVGSGKTfEMVASAMESKRLGMCSKSLFVVPNH-LTGQIGREFMQLYP---SANIMVADKKDFEPKNRKRfi 2001
Cdd:cd00046 1 GENVLITAPTGSGKT-LAALLAALLLLLKKGKKVLVLVPTKaLALQTAERLRELFGpgiRVAVLVGGSSAEEREKNKL-- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 489079422 2002 gkiatGEYDaVVIGHTQFekIPMSKEYQEKHIQDQIDEIV 2041
Cdd:cd00046 78 -----GDAD-IIIATPDM--LLNLLLREDRLFLKDLKLII 109
|
|
| |
