|
Name |
Accession |
Description |
Interval |
E-value |
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
13-427 |
0e+00 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 539.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 13 MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGPGAAP----EDIGGIVGADLRNSGKFNPLDRSRLPQQPGTAQEVQP 88
Cdd:TIGR02800 1 LAVSTPAAADLTIEITKGGASALPIAVAPFSNDGGGSPDanlgESIAEVIANDLKRSGLFSPVDKAGLPSNPIAESQVNP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 89 AAWSALGIDAVVVGQVTPNPDGSYSVAYQLVDTGGApGTVLAQNTYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIA 168
Cdd:TIGR02800 81 AAWQALGADALVVGSVTPNGNGRYTVRFRLYDVVSG-QLQLLGKQYTVTASQLRRVAHRIADAIYEKLTGERGAFSTRIA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 169 YVVQtNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLSNGAVRQVASFPRHNGA 248
Cdd:TIGR02800 160 YVSK-SGKSRRYELQVADYDGANPQTITRSREPILSPAWSPDGQKLAYVSFESGKPEIYVQDLATGQREKVASFPGMNGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 249 PAFSPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRIT 328
Cdd:TIGR02800 239 PAFSPDGSKLAVSLSKDGNPDIYVMDLDGKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDRGGSPQIYMMDADGGEVRRLT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 329 WEGSQNQDADVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDG 408
Cdd:TIGR02800 319 FRGGYNASPSWSPDGDLIAFVHREGGGFNIAVMDLDGGGERVLTDTGLDESPSFAPNGRMILYATTRGGRGVLGLVSTDG 398
|
410
....*....|....*....
gi 489113127 409 RFKARLPATDGQVKFPAWS 427
Cdd:TIGR02800 399 RFRARLPLGNGDVREPAWS 417
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
258-416 |
2.62e-46 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 157.14 E-value: 2.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 258 LAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRITWEGSQNQDA 337
Cdd:COG0823 1 LAFTLSRDGNSDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYNASP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489113127 338 DVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLSSTFLDetPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRfKARLPA 416
Cdd:COG0823 81 SWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS--PSWSPDGRRIVFSSDRGGRPDLYVVDLDGR-KRRLTP 156
|
|
| TolB_N |
pfam04052 |
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent ... |
23-121 |
1.28e-40 |
|
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent translocation system. This function of this amino terminal domain is uncertain.
Pssm-ID: 461148 Cd Length: 105 Bit Score: 140.06 E-value: 1.28e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 23 VRIEITQGVDSARPIGVVPFQWAGPGAAPEDIGGIVGADLRNSGKFNPLDRSRLPQQPGTAQEVQPAAWSALGIDAVVVG 102
Cdd:pfam04052 1 LRIEITGGGDTALPIAVVPFQGEGGADLPQDISEVIAADLERSGLFRPIDPAAFPQRPTSDSEVDFADWRALGADALVTG 80
|
90
....*....|....*....
gi 489113127 103 QVTPNPDGSYSVAYQLVDT 121
Cdd:pfam04052 81 SVTRGGDGRYKVEFRLYDV 99
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
146-426 |
1.46e-25 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 107.93 E-value: 1.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 146 HTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPY---ELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLA--YVTFE 220
Cdd:PRK01029 128 HEAADTIHYALTGVPGISSGKIIFSLSTTNSDTELkqgELWSVDYDGQNLRPLTQEHSLSITPTWMHIGSGFPylYVSYK 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 221 SGRSALVIQTLSNGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDI-----GSGQIRQVTDGR-SNNTEPT 294
Cdd:PRK01029 208 LGVPKIFLGSLENPAGKKILALQGNQLMPTFSPRKKLLAFISDRYGNPDLFIQSFsletgAIGKPRRLLNEAfGTQGNPS 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 295 WFPDSQNLAFTSDQAGRPQVYKVNVN--GGAPQRITWEGSQNQDADVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLS 372
Cdd:PRK01029 288 FSPDGTRLVFVSNKDGRPRIYIMQIDpeGQSPRLLTKKYRNSSCPAWSPDGKKIAFCSVIKGVRQICVYDLATGRDYQLT 367
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 489113127 373 STFLD-ETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAW 426
Cdd:PRK01029 368 TSPENkESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVIGSGEKRFPSW 422
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
13-427 |
0e+00 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 539.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 13 MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGPGAAP----EDIGGIVGADLRNSGKFNPLDRSRLPQQPGTAQEVQP 88
Cdd:TIGR02800 1 LAVSTPAAADLTIEITKGGASALPIAVAPFSNDGGGSPDanlgESIAEVIANDLKRSGLFSPVDKAGLPSNPIAESQVNP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 89 AAWSALGIDAVVVGQVTPNPDGSYSVAYQLVDTGGApGTVLAQNTYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIA 168
Cdd:TIGR02800 81 AAWQALGADALVVGSVTPNGNGRYTVRFRLYDVVSG-QLQLLGKQYTVTASQLRRVAHRIADAIYEKLTGERGAFSTRIA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 169 YVVQtNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLSNGAVRQVASFPRHNGA 248
Cdd:TIGR02800 160 YVSK-SGKSRRYELQVADYDGANPQTITRSREPILSPAWSPDGQKLAYVSFESGKPEIYVQDLATGQREKVASFPGMNGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 249 PAFSPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRIT 328
Cdd:TIGR02800 239 PAFSPDGSKLAVSLSKDGNPDIYVMDLDGKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDRGGSPQIYMMDADGGEVRRLT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 329 WEGSQNQDADVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDG 408
Cdd:TIGR02800 319 FRGGYNASPSWSPDGDLIAFVHREGGGFNIAVMDLDGGGERVLTDTGLDESPSFAPNGRMILYATTRGGRGVLGLVSTDG 398
|
410
....*....|....*....
gi 489113127 409 RFKARLPATDGQVKFPAWS 427
Cdd:TIGR02800 399 RFRARLPLGNGDVREPAWS 417
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
258-416 |
2.62e-46 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 157.14 E-value: 2.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 258 LAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRITWEGSQNQDA 337
Cdd:COG0823 1 LAFTLSRDGNSDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYNASP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489113127 338 DVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLSSTFLDetPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRfKARLPA 416
Cdd:COG0823 81 SWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS--PSWSPDGRRIVFSSDRGGRPDLYVVDLDGR-KRRLTP 156
|
|
| TolB_N |
pfam04052 |
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent ... |
23-121 |
1.28e-40 |
|
TolB amino-terminal domain; TolB is an essential periplasmic component of the tol-dependent translocation system. This function of this amino terminal domain is uncertain.
Pssm-ID: 461148 Cd Length: 105 Bit Score: 140.06 E-value: 1.28e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 23 VRIEITQGVDSARPIGVVPFQWAGPGAAPEDIGGIVGADLRNSGKFNPLDRSRLPQQPGTAQEVQPAAWSALGIDAVVVG 102
Cdd:pfam04052 1 LRIEITGGGDTALPIAVVPFQGEGGADLPQDISEVIAADLERSGLFRPIDPAAFPQRPTSDSEVDFADWRALGADALVTG 80
|
90
....*....|....*....
gi 489113127 103 QVTPNPDGSYSVAYQLVDT 121
Cdd:pfam04052 81 SVTRGGDGRYKVEFRLYDV 99
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
167-328 |
3.99e-36 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 130.18 E-value: 3.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 167 IAYVVQTNGGqfpYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLSNGAVRQVASFPRHN 246
Cdd:COG0823 1 LAFTLSRDGN---SDIYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPRRLTFGGGYN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 247 GAPAFSPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNntePTWFPDSQNLAFTSDQAGRPQVYKVNVNGGaPQR 326
Cdd:COG0823 78 ASPSWSPDGKRLAFVSRSDGRFDIYVLDLDGGAPRRLTDGPGS---PSWSPDGRRIVFSSDRGGRPDLYVVDLDGR-KRR 153
|
..
gi 489113127 327 IT 328
Cdd:COG0823 154 LT 155
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
146-426 |
1.46e-25 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 107.93 E-value: 1.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 146 HTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPY---ELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLA--YVTFE 220
Cdd:PRK01029 128 HEAADTIHYALTGVPGISSGKIIFSLSTTNSDTELkqgELWSVDYDGQNLRPLTQEHSLSITPTWMHIGSGFPylYVSYK 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 221 SGRSALVIQTLSNGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDI-----GSGQIRQVTDGR-SNNTEPT 294
Cdd:PRK01029 208 LGVPKIFLGSLENPAGKKILALQGNQLMPTFSPRKKLLAFISDRYGNPDLFIQSFsletgAIGKPRRLLNEAfGTQGNPS 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 295 WFPDSQNLAFTSDQAGRPQVYKVNVN--GGAPQRITWEGSQNQDADVSSDGKFMVMVSSANGQQHIAKQDLVAGGVQVLS 372
Cdd:PRK01029 288 FSPDGTRLVFVSNKDGRPRIYIMQIDpeGQSPRLLTKKYRNSSCPAWSPDGKKIAFCSVIKGVRQICVYDLATGRDYQLT 367
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 489113127 373 STFLD-ETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAW 426
Cdd:PRK01029 368 TSPENkESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVIGSGEKRFPSW 422
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
204-351 |
7.53e-24 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 104.74 E-value: 7.53e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 204 SPAWSPDGSKLAYVTFESGRSALVIQTLSN-GAVRQVASF-PRHNGAPAFSPDGSKLAFAlskTGSLNLYVMDIGSGQIR 281
Cdd:COG4946 347 LPAWSPDGKSIAYFSDASGEYELYIAPADGsGEPKQLTLGdLGRVFNPVWSPDGKKIAFT---DNRGRLWVVDLASGKVR 423
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489113127 282 QVTDGRSN--NTEPTWFPDSQNLAFT-SDQAGRPQVYKVNVNGGAPQRITWEGSQNQDADVSSDGKFMVMVSS 351
Cdd:COG4946 424 KVDTDGYGdgISDLAWSPDSKWLAYSkPGPNQLSQIFLYDVETGKTVQLTDGRYDDGSPAFSPDGKYLYFLSS 496
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
184-313 |
1.38e-18 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 88.56 E-value: 1.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 184 VSDYDGYNQFVVHRS-----PQPL--------MSPAWSPDGSKLAYVtfeSGRSALVIQTLSNGAVRQVAS--FPRHNGA 248
Cdd:COG4946 360 FSDASGEYELYIAPAdgsgePKQLtlgdlgrvFNPVWSPDGKKIAFT---DNRGRLWVVDLASGKVRKVDTdgYGDGISD 436
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489113127 249 PAFSPDGSKLAFALSKTGSL-NLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQ 313
Cdd:COG4946 437 LAWSPDSKWLAYSKPGPNQLsQIFLYDVETGKTVQLTDGRYDDGSPAFSPDGKYLYFLSSRDFNPT 502
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
204-335 |
4.80e-18 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 85.58 E-value: 4.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 204 SPAWSPDGSKLAYVTFESGRSALVIQTLS--NGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDIGSGQIR 281
Cdd:PRK01029 285 NPSFSPDGTRLVFVSNKDGRPRIYIMQIDpeGQSPRLLTKKYRNSSCPAWSPDGKKIAFCSVIKGVRQICVYDLATGRDY 364
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489113127 282 QVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRIT----------WEGSQNQ 335
Cdd:PRK01029 365 QLTTSPENKESPSWAIDSLHLVYSAGNSNESELYLISLITKKTRKIVigsgekrfpsWGAFPSQ 428
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
249-347 |
6.11e-16 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 80.47 E-value: 6.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 249 PAFSPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQ----AGRPQVYKVNVNGGAP 324
Cdd:COG4946 66 PRFSPDGKWIAFTSDYDGNTDVYVMPAEGGEPKRLTYHPANDRVVGWTPDGKSVLFASNRgsppSRSNQLYTVPVDGGLP 145
|
90 100
....*....|....*....|....
gi 489113127 325 QRITW-EGSqnqDADVSSDGKFMV 347
Cdd:COG4946 146 ERLPLpPAG---DGSFSPDGKKLA 166
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
203-428 |
2.17e-13 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 72.38 E-value: 2.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 203 MSPAWSPDGSKLAYV----------------------TFESGRSALVIQTLSNGAV----RQVASFPRHN---------- 246
Cdd:COG4946 64 SFPRFSPDGKWIAFTsdydgntdvyvmpaeggepkrlTYHPANDRVVGWTPDGKSVlfasNRGSPPSRSNqlytvpvdgg 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 247 ----------GAPAFSPDGSKLAFAlSKTGSLN------------LYVMDIGSGQIRQVTDGRSNNTEPTWFPDsqNLAF 304
Cdd:COG4946 144 lperlplppaGDGSFSPDGKKLAYT-RIGREFRtwkryrggtagdIWIYDLGTGEFTRLTDFGGNDRNPMWIGD--RIYF 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 305 TSDQAGRPQVYKVNVNGGAPQRITwegsQNQDADV---SSDGKFMVMvsSANGQQHiaKQDLVAGGVQVLS----STFLD 377
Cdd:COG4946 221 LSDRDGTFNLYSYDPDGKDLRQLT----HFKDFDVrfpSTDGGRIVY--EQGGDLY--LLDLASGEPRKLNitlaGDFPQ 292
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 378 ETP------------SLAPNGTMV-------IYSSSQGMGSVLNLVSTDGrfkarlpatdGQVKFPAWSP 428
Cdd:COG4946 293 RRPrwvdvsgyltsfALSPDGKRVafeargeVFTVPAEKGPTRNLTNTPG----------VRERLPAWSP 352
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
269-392 |
1.25e-11 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 66.99 E-value: 1.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 269 NLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRITWEGSQNQDADVSSDGKfMVM 348
Cdd:COG4946 42 DLWTVPADGGRARRLTSHPGYESFPRFSPDGKWIAFTSDYDGNTDVYVMPAEGGEPKRLTYHPANDRVVGWTPDGK-SVL 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 489113127 349 VSSANGQQHIAKQDL----VAGG-VQVLS---STFLdetpSLAPNGTMVIYS 392
Cdd:COG4946 121 FASNRGSPPSRSNQLytvpVDGGlPERLPlppAGDG----SFSPDGKKLAYT 168
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
199-428 |
1.82e-09 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 60.05 E-value: 1.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 199 PQPLMSP-----AWSPDGSKLAYVTFESGRSA-----------LVIQTLSNGAVRQVASFPRHNGAPAFSpdGSKLAFAL 262
Cdd:COG4946 145 PERLPLPpagdgSFSPDGKKLAYTRIGREFRTwkryrggtagdIWIYDLGTGEFTRLTDFGGNDRNPMWI--GDRIYFLS 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 263 SKTGSLNLYVMDIGSGQIRQVT----------------------------DGRSNNTE--------------PTWF---- 296
Cdd:COG4946 223 DRDGTFNLYSYDPDGKDLRQLThfkdfdvrfpstdggrivyeqggdlyllDLASGEPRklnitlagdfpqrrPRWVdvsg 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 297 --------PDSQNLAFTSdqagRPQVYKVNVNGGAPQRITWE-GSQNQDADVSSDGKFMVMVSSANGQQHIAKQDLVAGG 367
Cdd:COG4946 303 yltsfalsPDGKRVAFEA----RGEVFTVPAEKGPTRNLTNTpGVRERLPAWSPDGKSIAYFSDASGEYELYIAPADGSG 378
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489113127 368 --VQVLSSTFLDET-PSLAPNGTMVIYSSSQGmgsVLNLVSTDGRfKARLPATDGQ---VKFPAWSP 428
Cdd:COG4946 379 epKQLTLGDLGRVFnPVWSPDGKKIAFTDNRG---RLWVVDLASG-KVRKVDTDGYgdgISDLAWSP 441
|
|
| tolB |
PRK04043 |
Tol-Pal system protein TolB; |
252-350 |
3.91e-09 |
|
Tol-Pal system protein TolB;
Pssm-ID: 235212 [Multi-domain] Cd Length: 419 Bit Score: 58.08 E-value: 3.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 252 SPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNVNGGAPQRITWEG 331
Cdd:PRK04043 241 SKDGSKLLLTMAPKGQPDIYLYDTNTKTLTQITNYPGIDVNGNFVEDDKRIVFVSDRLGYPNIFMKKLNSGSVEQVVFHG 320
|
90
....*....|....*....
gi 489113127 332 sQNQDAdVSSDGKFMVMVS 350
Cdd:PRK04043 321 -KNNSS-VSTYKNYIVYSS 337
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
280-316 |
1.88e-08 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 49.82 E-value: 1.88e-08
10 20 30
....*....|....*....|....*....|....*..
gi 489113127 280 IRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYK 316
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
236-272 |
1.09e-07 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 47.90 E-value: 1.09e-07
10 20 30
....*....|....*....|....*....|....*..
gi 489113127 236 VRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYV 272
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| Peptidase_S9_N |
pfam02897 |
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded ... |
247-354 |
5.35e-06 |
|
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded beta-propeller domain protects the catalytic triad of prolyl oligopeptidase (see pfam00326), excluding larger peptides and proteins from proteolysis in the cytosol.
Pssm-ID: 397164 [Multi-domain] Cd Length: 414 Bit Score: 48.46 E-value: 5.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 247 GAPAFSPDGSKLAFALSKTGS--LNLYVMDIGSGQirQVTDG--RSNNTEPTWFPDSQNLAFTS-DQAGRPQVYKVNVNG 321
Cdd:pfam02897 127 GGFAFSPDGRLLAYSLSLSGSdwYTIRFRDVETGE--DLPDVleGVKFSGIVWAPDGKGFFYTRyDKPDERSDTGTNLNQ 204
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 489113127 322 -------GAPQ---RITWEGSQNQD----ADVSSDGKFmVMVSSANG 354
Cdd:pfam02897 205 kvwrhrlGTPQsqdVLVFEFPKDPLwslgAERSEDGKY-LFISSASG 250
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
182-428 |
9.11e-06 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 47.60 E-value: 9.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 182 LRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVtfeSGRSALVIQTLSNGavRQVASFPRHNGAP---AFSPDGSKL 258
Cdd:COG2319 61 LLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASA---SADGTVRLWDLATG--LLLRTLTGHTGAVrsvAFSPDGKTL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 259 AFAlSKTGSLNLYvmDIGSGQIRQVTDGRSNNTEP-TWFPDSQNLAFTSDQAgrpQVYKVNVNGGAPQRiTWEGSQN--Q 335
Cdd:COG2319 136 ASG-SADGTVRLW--DLATGKLLRTLTGHSGAVTSvAFSPDGKLLASGSDDG---TVRLWDLATGKLLR-TLTGHTGavR 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 336 DADVSSDGKFMVMVS--------SANGQQHIAKqdLVAGGVQVLSSTFldetpslAPNGTMVIYSSSQGMGSVLNLvsTD 407
Cdd:COG2319 209 SVAFSPDGKLLASGSadgtvrlwDLATGKLLRT--LTGHSGSVRSVAF-------SPDGRLLASGSADGTVRLWDL--AT 277
|
250 260
....*....|....*....|.
gi 489113127 408 GRFKARLPATDGQVKFPAWSP 428
Cdd:COG2319 278 GELLRTLTGHSGGVNSVAFSP 298
|
|
| Pectate_lyase22 |
pfam14583 |
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more ... |
207-315 |
2.16e-05 |
|
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.
Pssm-ID: 434052 [Multi-domain] Cd Length: 386 Bit Score: 46.55 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 207 WSPDGSKLAYVTFESGRSALVI-----QTLSNgavRQVASFP-------RHNGAPAFSpDGSKLAFALSKTGSLN----- 269
Cdd:pfam14583 245 WVPDGSALVYVSYLKGSTDRFIysadpVTLEN---RQLTSMPacshlmsNYDGTLMVG-DGSDAPVDVQDDSGYKiendp 320
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 489113127 270 -LYVMDIGSGQIRQVT-----------DGRSNNTEPTWFPDSQNLAFTSDQAGRPQVY 315
Cdd:pfam14583 321 fLYVFNMKNGTQHRVArhdtswevfegDRQVTHPHPSFTPDDKQILFTSDVHGKPALY 378
|
|
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
195-411 |
4.28e-05 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 45.39 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 195 VHRSPQPLMSPAWSPDGSKLAYVtFESGrsaLVIQTLSNGAVRQV---ASFPRHNGAP---------------AFSPDGS 256
Cdd:pfam00930 38 LPPGEGKIQDAKWSPDGDRLAFV-RDNN---LYVRELATGKEIQItsdGSDGIFNGVAdwvyeeevlgsnsavWWSPDGS 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 257 KLAFA----------------------------LSKTGSLN----LYVMDIGSGQIRQVTDGRSNNTEP------TWFPD 298
Cdd:pfam00930 114 RLAFLrfdesevpiitlpyytdegpgpevreikYPKAGAPNptveLFVYDLASGKTVEVVPPDDLSDADyyitrvKWVPD 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 299 SqNLAFTsdQAGRPQ----VYKVNVNGGAPQRITWEGSQ---NQDADV----SSDGKFmVMVSSANGQQHIAKQDLVAGG 367
Cdd:pfam00930 194 G-KLLVQ--WLNRDQnrlkVVLCDAETGRTVVILEETSDgwvELHQDPhfikRDGSGF-LWISERDGYNHLYLYDLDGKS 269
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 489113127 368 VQVLSSTFLDETPSLAPNGTM--VIYSSSQGMGSVLNL--VSTDGRFK 411
Cdd:pfam00930 270 PIQLTSGNWEVTSILGVDETRdlVYFTATEDSPTERHLysVSLDSGGE 317
|
|
| Pectate_lyase22 |
pfam14583 |
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more ... |
251-307 |
4.61e-04 |
|
Oligogalacturonate lyase; This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.
Pssm-ID: 434052 [Multi-domain] Cd Length: 386 Bit Score: 42.31 E-value: 4.61e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 489113127 251 FSPDGSKLAFALSKTGSLNLYVMDIGSGQIRQVTDGRSNNTEPTWF-PDSQNLAFTSD 307
Cdd:pfam14583 43 FTRDGSKLLFGGAFDGPWNYYLLDLNTQVATQLTEGRGDNTFGGFLsPDDDALFYVKD 100
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
204-351 |
5.32e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 42.21 E-value: 5.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 204 SPAWSPDGSKLAYVtfeSGRSALVIQTLSNGavRQVASFPRHNGAP---AFSPDGSKLAFAlSKTGSLNLYvmDIGSGQI 280
Cdd:COG2319 251 SVAFSPDGRLLASG---SADGTVRLWDLATG--ELLRTLTGHSGGVnsvAFSPDGKLLASG-SDDGTVRLW--DLATGKL 322
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489113127 281 RQVTDGRSNNTEP-TWFPDSQNLAFTSDQAGrpqVYKVNVNGGAPQRiTWEGSQNQ--DADVSSDGKFMVMVSS 351
Cdd:COG2319 323 LRTLTGHTGAVRSvAFSPDGKTLASGSDDGT---VRLWDLATGELLR-TLTGHTGAvtSVAFSPDGRTLASGSA 392
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
88-311 |
5.68e-04 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.22 E-value: 5.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 88 PAAWSALGIDAVVVGQVTPNPDGSYSVAYQLVDTGGAPGTVLAQNTYKVnkqwlrYAGHTASDEVFEKLTGIKGafrtRI 167
Cdd:COG3391 12 LLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGL------GLGAAAVADADGADAGADG----RR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 168 AYVVQTNGGqfpyelRVSDYDGYNQFVVHR-----SPQPLmspAWSPDGSKLaYVTFESGRSALVIQTLSNGAVRQVASF 242
Cdd:COG3391 82 LYVANSGSG------RVSVIDLATGKVVATipvggGPRGL---AVDPDGGRL-YVADSGNGRVSVIDTATGKVVATIPVG 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489113127 243 PRHNGApAFSPDGSKlafalsktgslnLYVMDIGSGQIR---QVTDGRSNNTEPTWFPDSQNLAFTSDQAGR 311
Cdd:COG3391 152 AGPHGI-AVDPDGKR------------LYVANSGSNTVSvivSVIDTATGKVVATIPVGGGPVGVAVSPDGR 210
|
|
| DPPIV_N |
pfam00930 |
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ... |
252-332 |
6.43e-04 |
|
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Pssm-ID: 395744 [Multi-domain] Cd Length: 352 Bit Score: 41.53 E-value: 6.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489113127 252 SPDGSKLAFALSKT------GSLNLYVMDIGSGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQagrpQVYKVNVNGGAPQ 325
Cdd:pfam00930 1 SPDGKYLLLATNYTknwrhsYTADYYIYDLETNRVEPLPPGEGKIQDAKWSPDGDRLAFVRDN----NLYVRELATGKEI 76
|
....*..
gi 489113127 326 RITWEGS 332
Cdd:pfam00930 77 QITSDGS 83
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
198-224 |
1.95e-03 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 35.57 E-value: 1.95e-03
10 20
....*....|....*....|....*..
gi 489113127 198 SPQPLMSPAWSPDGSKLAYVTFESGRS 224
Cdd:pfam07676 7 TPGNETAPSWSPDGKRLAFSSDRDGKP 33
|
|
| |
