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Conserved domains on  [gi|489115839|ref|WP_003025688|]
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MULTISPECIES: D-serine/D-alanine/glycine transporter [Citrobacter]

Protein Classification

D-serine/D-alanine/glycine transporter( domain architecture ID 11485166)

D-serine/D-alanine/glycine transporter, belonging to the APC (amino acid/polyamine/organocation) family, acts as a permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine

Gene Symbol:  cycA
Gene Ontology:  GO:0006865|GO:0055085|GO:0022857|GO:0015171|GO:0003333
PubMed:  10931886|19670073|24038584|25043943
TCDB:  2.A.3.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 2-469 0e+00

D-alanine/D-serine/glycine permease; Provisional


:

Pssm-ID: 236830  Cd Length: 469  Bit Score: 877.91  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   2 VDQVKVDTAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 81
Cdd:PRK11049   1 VDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  82 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEME 161
Cdd:PRK11049  81 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 162 FWFAMIKIVAIIGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 241
Cdd:PRK11049 161 FWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 242 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRM 321
Cdd:PRK11049 241 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRM 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 322 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQR 401
Cdd:PRK11049 321 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYRKQR 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489115839 402 PHLHEKSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKRMAGMR 469
Cdd:PRK11049 401 PHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 2-469 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 877.91  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   2 VDQVKVDTAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 81
Cdd:PRK11049   1 VDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  82 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEME 161
Cdd:PRK11049  81 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 162 FWFAMIKIVAIIGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 241
Cdd:PRK11049 161 FWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 242 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRM 321
Cdd:PRK11049 241 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRM 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 322 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQR 401
Cdd:PRK11049 321 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYRKQR 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489115839 402 PHLHEKSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKRMAGMR 469
Cdd:PRK11049 401 PHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
9-464 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 656.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   9 TAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFS 88
Cdd:COG1113    3 TSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  89 DFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIK 168
Cdd:COG1113   83 DYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIK 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 169 IVAIIGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRA 248
Cdd:COG1113  163 VVAIVAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 249 INSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQE 328
Cdd:COG1113  243 INSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAER 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 329 GVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSviGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLH-EK 407
Cdd:COG1113  323 GDAPKFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGaAA 400

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489115839 408 SIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKR 464
Cdd:COG1113  401 LKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRR 457
AA_permease pfam00324
Amino acid permease;
27-464 1.15e-111

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 337.37  E-value: 1.15e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   27 HIQLIAIGGAIGTGLFMGSGKTISLAGP-SIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYFTGW 105
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPaGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  106 TYWFCWVVTGMADVVAITAYAQFW--FPELS-DWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGLIVVGLVm 182
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGII- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  183 vlTHFQSPTGVQASFTHLWNDGG--WFPKG-LSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMF 259
Cdd:pfam00324 160 --LLSGGNPNDGAIFRYLGDNGGknNFPPGfGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  260 YVFALIVIMSVTPWSSVVPTK------SPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPK 333
Cdd:pfam00324 238 YILSLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  334 AFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVigAFTMITTVSAILFMFVWTIILCSYLVYRKQ---RPHLHEKSIY 410
Cdd:pfam00324 318 FLKKVDKRGVPLRAILVSMVISLLALLLASLNPAI--VFNFLLAISGLSGLIVWGLISLSHLRFRKAfkyQGRSIDELPF 395

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489115839  411 KMPLGKLMCWVCMAFFVFVLVLLTLEDDTR-------------QALMVTPLWFIALGLGWLFIGKKR 464
Cdd:pfam00324 396 KAPLGPLGVILGLAAIIIILIIQFLYAFLPvpggpknwgagsfAAAYLIVLLFLIILIGVKLHVKNW 462
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 12-448 6.94e-87

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 273.28  E-value: 6.94e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   12 EASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFA 91
Cdd:TIGR01773   3 QSQSGLKLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   92 SDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVA 171
Cdd:TIGR01773  83 DDAIGRWAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  172 IIGLIVVGLVMVLTHFqsPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINS 251
Cdd:TIGR01773 163 IIAFIILGAVAIFGFA--PGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  252 IPIRIIMFYVFALIVIMSVTPWSSVVPTKS-PFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGV 330
Cdd:TIGR01773 241 VIWRIIVFYLGSIFIVVALLPWNSPNLLEVgSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGD 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  331 APKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIY 410
Cdd:TIGR01773 321 APRVFMKLNKKGVPVQAVLASTFFSFLTVVVNYFAPDKV--FLFLVNSSGAIALLVYLVIAVSQLRMRKKLKANGEAIKI 398

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 489115839  411 KMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPL 448
Cdd:TIGR01773 399 RMWLYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGL 436
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 2-469 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 877.91  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   2 VDQVKVDTAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 81
Cdd:PRK11049   1 VDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  82 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEME 161
Cdd:PRK11049  81 LEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 162 FWFAMIKIVAIIGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 241
Cdd:PRK11049 161 FWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 242 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRM 321
Cdd:PRK11049 241 EKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRM 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 322 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQR 401
Cdd:PRK11049 321 LFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYRKQR 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489115839 402 PHLHEKSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKRMAGMR 469
Cdd:PRK11049 401 PHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
9-464 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 656.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   9 TAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFS 88
Cdd:COG1113    3 TSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSFS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  89 DFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIK 168
Cdd:COG1113   83 DYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALIK 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 169 IVAIIGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRA 248
Cdd:COG1113  163 VVAIVAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPKA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 249 INSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQE 328
Cdd:COG1113  243 INSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAER 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 329 GVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSviGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLH-EK 407
Cdd:COG1113  323 GDAPKFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGaAA 400

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489115839 408 SIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKR 464
Cdd:COG1113  401 LKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRR 457
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
10-469 1.34e-126

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 375.66  E-value: 1.34e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  10 AEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGP-SIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFS 88
Cdd:COG0833    1 SSGSEKQNKLKRGLKSRHLSMIALGGVIGTGLFLASGYTISQAGPgGALLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  89 DFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIK 168
Cdd:COG0833   81 TYATRFIDPAFGFAVGWNYWLNWAITVAAELTAAGIIMQYWFPDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 169 IVAIIGLIVVGLVMVlthFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRA 248
Cdd:COG0833  161 VITVIAFIIVGLLMI---FGIIGGHAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 249 INSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQE 328
Cdd:COG0833  238 IRQVFWRILLFYILAIFVIAALIPYTDAGVAESPFTLVFERAGIPYAADIMNAVILTAVLSAGNSGLYASTRMLWSLAKE 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 329 GVAPKAFAKLSKRAVPAKGLTFS----CICLLGGVvmlyVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQ---R 401
Cdd:COG0833  318 GMAPKIFAKLNKRGVPLNALLATmavgLLALLSSF----FGAGTV--YLWLLSISGLTGFIAWLGIAISHYRFRRAyvaQ 391

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489115839 402 PHLHEKSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKRMAGMR 469
Cdd:COG0833  392 GGDLEDLKYKAPLFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLGYKLKKKTKLVPLE 459
PRK10238 PRK10238
aromatic amino acid transporter AroP;
17-466 2.95e-116

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 348.87  E-value: 2.95e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  17 QSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLG 96
Cdd:PRK10238   8 EQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  97 PWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGLI 176
Cdd:PRK10238  88 SFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMI 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 177 VVGLVMVlthFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRI 256
Cdd:PRK10238 168 IFGGWLL---FSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRI 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 257 IMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFA 336
Cdd:PRK10238 245 LIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALA 324

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 337 KLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMfvWTIILCSYLVYRKQRPHLHEKSIYKMPLGK 416
Cdd:PRK10238 325 SVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVIN--WAMISLAHMKFRRAKQEQGVVTRFPALLYP 402

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 489115839 417 LMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKKRMA 466
Cdd:PRK10238 403 LGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTAKA 452
AA_permease pfam00324
Amino acid permease;
27-464 1.15e-111

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 337.37  E-value: 1.15e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   27 HIQLIAIGGAIGTGLFMGSGKTISLAGP-SIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYFTGW 105
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPaGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  106 TYWFCWVVTGMADVVAITAYAQFW--FPELS-DWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGLIVVGLVm 182
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGII- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  183 vlTHFQSPTGVQASFTHLWNDGG--WFPKG-LSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMF 259
Cdd:pfam00324 160 --LLSGGNPNDGAIFRYLGDNGGknNFPPGfGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  260 YVFALIVIMSVTPWSSVVPTK------SPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPK 333
Cdd:pfam00324 238 YILSLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  334 AFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVigAFTMITTVSAILFMFVWTIILCSYLVYRKQ---RPHLHEKSIY 410
Cdd:pfam00324 318 FLKKVDKRGVPLRAILVSMVISLLALLLASLNPAI--VFNFLLAISGLSGLIVWGLISLSHLRFRKAfkyQGRSIDELPF 395

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489115839  411 KMPLGKLMCWVCMAFFVFVLVLLTLEDDTR-------------QALMVTPLWFIALGLGWLFIGKKR 464
Cdd:pfam00324 396 KAPLGPLGVILGLAAIIIILIIQFLYAFLPvpggpknwgagsfAAAYLIVLLFLIILIGVKLHVKNW 462
proY PRK10580
putative proline-specific permease; Provisional
 15-463 1.24e-110

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 334.48  E-value: 1.24e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  15 SEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDL 94
Cdd:PRK10580   3 SKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQEN 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  95 LGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIG 174
Cdd:PRK10580  83 LGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIII 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 175 LIVVGLVMV---LTHFQSPTGVQasftHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINS 251
Cdd:PRK10580 163 MIVAGIGIIiwgIGNGGQPTGIH----NLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINS 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 252 IPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVA 331
Cdd:PRK10580 239 VPMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSA 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 332 PKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSI-Y 410
Cdd:PRK10580 319 PKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENV--FLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALkF 396

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489115839 411 KMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKK 463
Cdd:PRK10580 397 KVPGGVATTIGGLIFLVFIIGLIGYHPDTRISLYVGFAWIVLLLIGWMFKRRH 449
PRK10249 PRK10249
phenylalanine transporter; Provisional
 9-463 3.29e-108

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 328.48  E-value: 3.29e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   9 TAEEASSEQ--SLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKS 86
Cdd:PRK10249   7 VSEDTASNQepTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  87 FSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAM 166
Cdd:PRK10249  87 FAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFAL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 167 IKIVAIIGLIVVGLVMVlthFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLP 246
Cdd:PRK10249 167 IKVLAIIGMIGFGLWLL---FSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIP 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 247 RAINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLA 326
Cdd:PRK10249 244 KAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLS 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 327 QEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSviGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHE 406
Cdd:PRK10249 324 VQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQ--KAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQGR 401

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489115839 407 KSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIGKK 463
Cdd:PRK10249 402 ETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTLRRK 458
PRK10746 PRK10746
putative transport protein YifK; Provisional
 13-461 5.01e-107

putative transport protein YifK; Provisional


Pssm-ID: 182694  Cd Length: 461  Bit Score: 325.62  E-value: 5.01e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  13 ASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFAS 92
Cdd:PRK10746   2 ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  93 DLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAI 172
Cdd:PRK10746  82 RYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 173 IGLIVVGLVMVLTHFQSpTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSI 252
Cdd:PRK10746 162 IVMIVIGLGVIFFGFGN-GGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 253 PIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAP 332
Cdd:PRK10746 241 LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 333 KAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQrphlHEKSIYKM 412
Cdd:PRK10746 321 AAMAKVSRHGVPVAGVAVSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRA----HKAAIASH 396

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489115839 413 PLGKLMC----WVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIALGLGWLFIG 461
Cdd:PRK10746 397 PFRSILFpwanYLTMAFLICVLIGMYFNEDTRMSLFVGIIFLLAVTLIYKVFG 449
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 12-448 6.94e-87

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 273.28  E-value: 6.94e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   12 EASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFA 91
Cdd:TIGR01773   3 QSQSGLKLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   92 SDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVA 171
Cdd:TIGR01773  83 DDAIGRWAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  172 IIGLIVVGLVMVLTHFqsPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINS 251
Cdd:TIGR01773 163 IIAFIILGAVAIFGFA--PGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  252 IPIRIIMFYVFALIVIMSVTPWSSVVPTKS-PFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGV 330
Cdd:TIGR01773 241 VIWRIIVFYLGSIFIVVALLPWNSPNLLEVgSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGD 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  331 APKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIY 410
Cdd:TIGR01773 321 APRVFMKLNKKGVPVQAVLASTFFSFLTVVVNYFAPDKV--FLFLVNSSGAIALLVYLVIAVSQLRMRKKLKANGEAIKI 398

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 489115839  411 KMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALMVTPL 448
Cdd:TIGR01773 399 RMWLYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGL 436
PRK15049 PRK15049
L-asparagine permease;
14-463 2.56e-85

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 270.72  E-value: 2.56e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  14 SSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASD 93
Cdd:PRK15049  21 AHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYARE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  94 LLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFW--FPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVA 171
Cdd:PRK15049 101 FLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWgaFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLA 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 172 IIGLIVVGLVMvLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINS 251
Cdd:PRK15049 181 IVTFLVVGTVF-LGSGQPLDGNTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINS 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 252 IPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVA 331
Cdd:PRK15049 260 VIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSA 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 332 PKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSI-Y 410
Cdd:PRK15049 340 PSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRV--FEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADVsF 417

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489115839 411 KMPLGKLMCWVCMAFFVFVLVLLTLE-DDTRQALMVTPLWFIALGLGWLFIGKK 463
Cdd:PRK15049 418 KLPGAPFTSWLTLLFLLSVLVLMAFDyPNGTYTIAALPIIGILLVIGWFGVRKR 471
PRK10836 PRK10836
lysine transporter; Provisional
 14-348 5.55e-78

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 251.28  E-value: 5.55e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  14 SSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPS-IIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFAS 92
Cdd:PRK10836   8 TEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGgALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  93 DLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAI 172
Cdd:PRK10836  88 NYVEEGFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFSLIKVTTV 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 173 IGLIVVGLVMVLTHFQsptGVQASFTHLWNDG-GWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINS 251
Cdd:PRK10836 168 IVFIIVGVLMIIGIFK---GAEPAGWSNWTIGdAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAVRQ 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 252 IPIRIIMFYVFALIVIMSVTPWSSVVPTK--------SPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLF 323
Cdd:PRK10836 245 VFWRILLFYVFAILIISLIIPYTDPSLLRndvkdisvSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLY 324

                        330       340
                 ....*....|....*....|....*
gi 489115839 324 GLAQEGVAPKAFAKLSKRAVPAKGL 348
Cdd:PRK10836 325 TLACDGKAPRIFAKLSRGGVPRNAL 349
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 20-431 2.61e-76

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 246.43  E-value: 2.61e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   20 RRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGP-SIIFVYMIIGFMLFFVMRAMGEL-LLSNLEYKSFSDFASDLLGP 97
Cdd:TIGR00913   1 KKSLKQRHIQMIALGGTIGTGLLVGSGTALATGGPaGLLIGYAIMGSIIYCVMQSLGEMaTFYPVVSGSFATYASRFVDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   98 WAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGLIV 177
Cdd:TIGR00913  81 AFGFAVGWNYWLQWLIVLPLELVTASMTIQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGEAEFWFSSIKILAIIGFII 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  178 VGLVMVLTHFQSPTGVQAsftHLWNDGGWFPKGLS-----GFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSI 252
Cdd:TIGR00913 161 LSIILNCGGGPNHGYIGF---RYWHDPGAFAGGTIggrfkGVCSVFVTAAFSFGGTELVALTAGEAANPRKSIPRAAKRT 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  253 PIRIIMFYVFALIVIMSVTPW---------SSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLF 323
Cdd:TIGR00913 238 FWRILVFYILTLFLIGFLVPYndprllsssSSSDSAASPFVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRTLY 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  324 GLAQEGVAPKAFAKLSKRAVPAKGLTFSciCLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYR---KQ 400
Cdd:TIGR00913 318 ALAHQGLAPKIFAYVDRRGVPYVAVIVS--SLFGLLAFLAVSKKEAEVFTWLLNISGLSGFFTWMCICLSHIRFRkamKA 395

                         410       420       430
                  ....*....|....*....|....*....|.
gi 489115839  401 RPHLHEKSIYKMPLGKLMCWVCMAFFVFVLV 431
Cdd:TIGR00913 396 QGRSLDELPYKSQTGPYGSYYALFFNILILI 426
PRK11387 PRK11387
S-methylmethionine permease;
14-400 7.23e-72

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 234.75  E-value: 7.23e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  14 SSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPS-IIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFAS 92
Cdd:PRK11387   7 QQAGQFKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAAgTLLAYLIGALVVYLVMQCLGELSVAMPETGAFHVYAA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  93 DLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAI 172
Cdd:PRK11387  87 RYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQVPVWPWCLLFCALIFGLNVVSTRFFAEGEFWFSLIKVVTI 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 173 IGLIVVGLVMVLTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSI 252
Cdd:PRK11387 167 LAFIVLGGAAIFGFIPMQDGSPAPGLRNLTAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPAKVIPVAIRTT 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 253 PIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAP 332
Cdd:PRK11387 247 IARLVIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNEGTLP 326

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489115839 333 KAFAKLSKRAVPAKGLTFScicLLGGVVMLYvnPSVIGAFTMITTVSAI---LFMFVWTIILCSYLVYRKQ 400
Cdd:PRK11387 327 ACFARLTKRGIPLTALSVS---MLGGLLALF--SSVVAPDTVFVALSAIsgfAVVAVWLSICASHFMFRRR 392
PRK10197 PRK10197
GABA permease;
30-455 9.17e-58

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 197.15  E-value: 9.17e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  30 LIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYFTGWTYWF 109
Cdd:PRK10197   1 MLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 110 CWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGLIVVGLVMVLTHFqs 189
Cdd:PRK10197  81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFY-- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 190 PTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMS 269
Cdd:PRK10197 159 PYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 270 VTPWSSV-VPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKLSKRAVPAKGL 348
Cdd:PRK10197 239 LIPWNMPgLKAVGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAV 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 349 TFSCICLLGGVVMLYVNPSVIgaFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVF 428
Cdd:PRK10197 319 LLSTGAAFLTVVVNYYAPAKV--FKFLIDSSGAIALLVYLVIAVSQLRMRKILRAEGSEIRLRMWLYPWLTWLVIGFITF 396

                        410       420
                 ....*....|....*....|....*..
gi 489115839 429 VLVLLTLEddTRQALMVTPLWFIALGL 455
Cdd:PRK10197 397 VLVVMLFR--PAQQLEVISTGLLAIGI 421
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
14-464 2.45e-55

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 190.49  E-value: 2.45e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  14 SSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASD 93
Cdd:COG0531    4 GESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  94 LLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAII 173
Cdd:COG0531   84 ALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 174 GLIVVGLVMVLThfqsptgvqASFTHLWNDGGwfpkGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIP 253
Cdd:COG0531  164 LFIVVGLFAFDP---------ANFTPFLPAGG----GLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSL 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 254 IRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPK 333
Cdd:COG0531  231 LIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPK 310

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 334 AFAKLSKR-AVPAKGLTFSCICLLGGVVMLYvnpsviGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHekSIYKM 412
Cdd:COG0531  311 VFAKVHPRfGTPVNAILLTGVIALLLLLLGA------ASFTALASLASVGVLLAYLLVALAVIVLRRRRPDLP--RPFRV 382

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489115839 413 PLgKLMCWVCMAFFVFVLVLLTLEddtrqALMVTPLWfIALGLGWLFIGKKR 464
Cdd:COG0531  383 PL-PLIPILGILLCLFLLYLLGPG-----ALLIGLVL-LAIGLLLYLLYRRR 427
AA_permease_2 pfam13520
Amino acid permease;
31-453 8.89e-28

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 114.71  E-value: 8.89e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   31 IAIGGAIGTGLFMGSGktISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKS-FSDFASDLLGPWAGYFTGWTYWF 109
Cdd:pfam13520   9 LVIGSVIGSGIFVAPL--VASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGgIYVYLENAFGKFVAFLAGWSNWF 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  110 CWVVTGMA-DVVAITAYAQFWFPELSDW-----VASLAVIVLLLSLNLATVKMFGEMEFWFAMIKIVAIIGL-IVVGLVM 182
Cdd:pfam13520  87 AYVLGLASsASVAASYLLSALGPDLVPTtwltyGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILiIILGLVT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  183 VLTHFQSPTGVQASFthlwndggWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKdpEKSLPRAINSIPIRIIMFYVF 262
Cdd:pfam13520 167 ADGGGFNLLSGEWHT--------FFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYIL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  263 ALIVIMSVTPWSSVV---PTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAP--KAFAK 337
Cdd:pfam13520 237 VNIAFFGVVPDDEIAlssGLGQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPfsRFFAK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  338 LSKRAVPAKGLTFSCI-CLLGGVVMLYVNPsvigAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHeKSIYKMPLGK 416
Cdd:pfam13520 317 VNKFGSPIRAIILTAIlSLILLLLFLLSPA----AYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLG-RIPGRWPVAI 391

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 489115839  417 LMCwVCMAFFVFVLVLLTLEDDTRQALMVTPLWFIAL 453
Cdd:pfam13520 392 FGI-LFSLFLIVALFFPPVGPATGSSLNYAIILIVAF 427
PRK10644 PRK10644
arginine/agmatine antiporter;
90-410 5.47e-16

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 79.83  E-value: 5.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  90 FASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSD----WVASLAVIVLLLSLNLATVKMFGEMEFWFA 165
Cdd:PRK10644  76 YARRCFGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDplvlTITCVVVLWIFVLLNIVGPKMITRVQAVAT 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 166 MIKIVAIIGLIVVGLVMvlthFQSPTGVqasfthlwndGGWFPKGLSGFFA---GFQIAVFAFVGIELVGTTAAETKDPE 242
Cdd:PRK10644 156 VLALIPIVGIAVFGWFW----FRGETYM----------AAWNVSGLGTFGAiqsTLNVTLWSFIGVESASVAAGVVKNPK 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 243 KSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRML 322
Cdd:PRK10644 222 RNVPIATIGGVLIAAVCYVLSSTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTA 301

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 323 FGLAQEGVAPKAFAKLSKRAVPAKGLTFSCIcLLGGVVMLYVNPSVIGAFTMITTVSAI--LFMFVWTIILCSYLVYRKq 400
Cdd:PRK10644 302 KAAADDGLFPPIFARVNKAGTPVAGLLIVGV-LMTIFQLSSISPNASKEFGLVSSVSVIftLVPYLYTCAALLLLGHGH- 379

                        330
                 ....*....|
gi 489115839 401 rpHLHEKSIY 410
Cdd:PRK10644 380 --FGKARPAY 387
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 13-341 9.80e-16

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 79.47  E-value: 9.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   13 ASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTI-SLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFA 91
Cdd:TIGR00906  20 SREESKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVArNDSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   92 SDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAY---------AQF---WFPELSDWVAS----LAVIVLLLSLNLATVK 155
Cdd:TIGR00906 100 YVTVGELWAFITGWNLILEYVIGTAAVARSWSAYfdellnkqiGQFrrtYFKLNYDGLAEypdfFAVCLILLLAVLLSFG 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  156 MFGEMEFwfamIKIVAIIGLIVVGLVMVlTHFQSPTGVQASFTHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTA 235
Cdd:TIGR00906 180 VKESAWV----NKIFTAINILVLLFVII-AGFTKADVANWSITEEKGAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTG 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  236 AETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPtKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGV 315
Cdd:TIGR00906 255 EEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDP-DAPFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGM 333

                         330       340
                  ....*....|....*....|....*.
gi 489115839  316 FSTSRMLFGLAQEGVAPKAFAKLSKR 341
Cdd:TIGR00906 334 FPLPRVIYAMARDGLLFKWLAQINSK 359
2A0302 TIGR00905
transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several ...
 28-382 2.51e-12

transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129983  Cd Length: 473  Bit Score: 68.55  E-value: 2.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   28 IQLIA--IGGAIGTGLFMGSGKTISLAGPSIIFV-YMIIGFMLFFVMRAMGELLLSNLEYKS-FSDFASDLLGPWAGYFT 103
Cdd:TIGR00905  12 FALTAlvIGSMIGSGIFSLPQNLASVAGPGAVIIgWIITGVGMLALAFVFAILATKKPELDGgIYAYAREGFGPYIGFMS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  104 GWTYWFCWVVTGMADVVAITAYAQFWFPELSD---WVASLAVIVLLLS---LNLATVKMFGEMEFWFAMIKIVAIIGLIV 177
Cdd:TIGR00905  92 GWGYWLSAWIGNVAYAVLLFSALGYFFPLFGSgnpVPSILGASVLLWVftfLVLRGVRQAAFINTITTIAKLIPLFLFII 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  178 VGLVMvlthFQSPTGVQASFTHLWNDGGWFPKGLSGFFAgfqIAVFAFVGIE--LVGTTAAETKdpeKSLPRAINSIPIR 255
Cdd:TIGR00905 172 IGWFW----FKLDLFTADFWGHDVPSLGSVFSQVKNTML---VTLWVFIGIEgaVVSSGRAKNK---SDVGKATVLGTLG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  256 IIMFYVFALIVIMSVTPWSSVVPTKSPFVELFV--LVGlPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPK 333
Cdd:TIGR00905 242 ALVIYILITLLSLGVLPQQELANLPNPSMAAVLemIVG-KWGAVLISLGLIISVLGSLLSWTMLAAEVPFSAAKDGLFPK 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 489115839  334 AFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAIL 382
Cdd:TIGR00905 321 IFGRVNKNGAPSVALLLTNILIQLFLLLTLLTSSAYNVLVSLAVVMILV 369
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 8-405 8.08e-12

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 67.08  E-value: 8.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839    8 DTAEEASSEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAG-PSIIFVYMIIGfMLFFVMRAMGELLLSNLEYKS 86
Cdd:TIGR00911  29 ASTVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVSPKGVLKNAGsVGLALIMWAVC-GIFSIVGALVYAELGTTIPKS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839   87 FSDFA--SDLLGPWAGYFTGWtYWFCWVVTGMADVVAIT--------AYAQFWFPELSDWVASLAVIVLLLSLNLATVKM 156
Cdd:TIGR00911 108 GGEYNyiLEVFGPLLAFLRLW-IELLVIRPGSQAVNALNfaiyiltpVFPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKW 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  157 FGEMEFWFAMIKIVAIIGLIVVGLVMV----LTHFQSPTGVQASFTHLwndGGWfpkgLSGFFAGFqiavFAFVGIELVG 232
Cdd:TIGR00911 187 ATRVQDIFTACKLLALLLIIITGWVQLgkggVESLNPKNAFEGTETSA---GGI----VLAFYSGI----WAYGGWNYLN 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  233 TTAAETKDPEKSLPRAI-NSIPIrIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVgLPAAASLINFVVLTSAASSA 311
Cdd:TIGR00911 256 FVTEEVKNPYRTLPIAIiISMPI-VTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERL-LGVMSWAMPALVGLSCFGSV 333

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  312 NSGVFSTSRMLFGLAQEGVAPKAFAKLS-KRAVPAKGLTFSCIcllggVVMLYVNPSVIgaFTMITTVSAILFMFVWTII 390
Cdd:TIGR00911 334 NGSLFSSSRLFFVGGREGHLPSLLSMIHvKRLTPLPSLLIVCT-----LTLLMLFSGDI--YSLINLISFANWLFNALAV 406

                         410
                  ....*....|....*
gi 489115839  391 lCSYLVYRKQRPHLH 405
Cdd:TIGR00911 407 -AGLLWLRYKRPEMN 420
PRK11021 PRK11021
putative transporter; Provisional
 96-364 2.21e-08

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 56.07  E-value: 2.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  96 GPWAGYFTGWTYWFcwvVTGMADVVAITAYAQFW-----FPELSDWVASLAVIVLLLSLNLATVKMFGEMEFWFAMIkIV 170
Cdd:PRK11021  74 GPRLGRVTGWLFLS---VIPVGLPAALQIAAGFGqalfgWSSWQLLLAELLTLALLWLLNLRGASSSANLQTVIALL-IV 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 171 AIIGLIVVGLVMVLTHFQSPTGVQASFthlwndggwfpkglSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAIN 250
Cdd:PRK11021 150 ALVVAIWWAGDIKPADIPFPAPGSIEW--------------SGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALM 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 251 SIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVGLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGV 330
Cdd:PRK11021 216 IGLLLAGLVYWACTVVVLHFPAYGDKQAAAASLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVWSQAREGR 295

                        250       260       270
                 ....*....|....*....|....*....|....
gi 489115839 331 APKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYV 364
Cdd:PRK11021 296 PPSYLARLSARGVPVNALNAVLGCCAVSILLIYA 329
frlA PRK11357
amino acid permease;
15-424 2.61e-08

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 56.02  E-value: 2.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  15 SEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFV--YMIIGFMLFFVMRAMGELLLSNLEYKSFSDFAS 92
Cdd:PRK11357   2 GSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVlaFVIGGLIVIPQMCVYAELSTAYPENGADYVYLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  93 DLLGPWAGYFTGWTYWFCWVVTGMADV-VAITAYAQF---WFPELSDWVASLAVIVLLLsLNLATVKMFGEMEFWFAMIK 168
Cdd:PRK11357  82 NAGSRPLAFLSGWASFWANDAPSLSIMaLAIVSNLGFltpIDPLLGKFIAAGLIIAFML-LHLRSVEGGAAFQTLITIAK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 169 IVAIIGLIVVGLVMVL-THFQSPTGVQASFThlwndggwfpKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPR 247
Cdd:PRK11357 161 IIPFTIVIGLGIFWFKaENFAAPTTTAIGAT----------GSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPR 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 248 AINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFVELFVLVglPAAASLINFVVLTSAA----SSANSGVFSTSRMLF 323
Cdd:PRK11357 231 ALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWI--PALGSTAGIFVAITAMivilGSLSSCVMYQPRLEY 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 324 GLAQEGVAPKAFAKLS-KRAVPAKGLTFSCICllgGVVMLYVN--PSVIGAFTMITtvsailfMFVWTIILCSYLVYRKQ 400
Cdd:PRK11357 309 AMAKDNLFFKCFGHVHpKYNTPDVSIILQGAL---GIFFIFVSdlTSLLGYFTLVM-------CFKNTLTFGSIIWCRKR 378

                        410       420
                 ....*....|....*....|....
gi 489115839 401 RphlHEKSIYKMPLGKLMCWVCMA 424
Cdd:PRK11357 379 D---DYKPLWRTPAFGLMTTLAIA 399
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 197-435 3.24e-06

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 49.36  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  197 FTHLWND-GGWFPKGLSgFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAI-NSIPIRIIMFYVFALIVIMSVTPWS 274
Cdd:TIGR00907 202 FTNFNNStGGWKPGGFA-FLLGLLNPAWSMTGYDGTAHMAEEIENPEVVGPRAIiGAVAIGIVTGFCFNIVLFFSMGDID 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  275 SVV--PTKSPFVELFVLV-GLPAAASLINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA--FAKLSKRA-VPAKGL 348
Cdd:TIGR00907 281 SLIssTTGQPIAQIFYNAlGNKAGAIFLLCLILVTSFFCAITCMTANSRMIYAFSRDGGLPFSplWSRVNPRTqVPLNAV 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  349 TFSCICLlggVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIYKmpLGKLMCWVCMAFFVF 428
Cdd:TIGR00907 361 WLSAVWI---ILIGLLGLGSSTAFQAIFSVCTVALDVSYVIPIICKLAKGRNTIAPGPFWLGK--YGFFVNAVAVAWTVF 435


                  ....*..
gi 489115839  429 VLVLLTL 435
Cdd:TIGR00907 436 SSVLFSF 442
PRK15238 PRK15238
inner membrane transporter YjeM; Provisional
 170-281 8.89e-05

inner membrane transporter YjeM; Provisional


Pssm-ID: 237929 [Multi-domain]  Cd Length: 496  Bit Score: 44.93  E-value: 8.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 170 VAIIGLIVVGLVMVLTHFQSPTGVQA-SFTHLWNDGGWFPKGLSGFFAgfqIAVFAFVGIELVGTTAAETKDPEKSLPRA 248
Cdd:PRK15238 171 LNIVLLLVSIIILILNGGHFAQPIGVsSFVTSPNPAYQSPIAVLSFVV---FAIFAYGGIEAVGGLVDKTENPEKNFPKG 247

                         90       100       110
                 ....*....|....*....|....*....|...
gi 489115839 249 INSIPIRIIMFYVFALIVIMSVTPWSSVVPTKS 281
Cdd:PRK15238 248 IIIAAIVISIGYSLAIFLWGVSTNWQQVLSNKS 280
cadB PRK10435
cadaverine/lysine antiporter;
95-385 6.88e-04

cadaverine/lysine antiporter;


Pssm-ID: 182458  Cd Length: 435  Bit Score: 42.04  E-value: 6.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839  95 LGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPELSDWV-ASLAVIVLLLSLNLatVKMFGEmefwfAMIKIVAII 173
Cdd:PRK10435  77 ISPAFGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPVLNDPIpAGIACIAIVWVFTF--VNMLGG-----TWVSRLTTI 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 174 GLIVVGLVMVLT------HFQSptgvqASFTHLWNDGGwfPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPR 247
Cdd:PRK10435 150 GLVLVLIPVVGTaivgwhWFDA-----ATYAANWNTSD--TTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPL 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489115839 248 AINSIPIRIIMFYVFALIVIMSVTPWSSVVPTKSPFV----ELFVLVGLPAAASLINFVVLTSAASSAnsgvfstsrMLF 323
Cdd:PRK10435 223 ATMLGTGLAGIIYIAATQVISGMFPASVMAASGAPFAisasTILGNWAAPLVSAFTAFACLTSLGSWM---------MLV 293

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489115839 324 G-----LAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGA----FTMITTVSAILFMF 385
Cdd:PRK10435 294 GqagvrAANDGNFPKVYGEVDKNGIPKKGLLLAAVKMTALMILITLMNSSGGKasdlFGELTGIAVLLTML 364
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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