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Conserved domains on  [gi|489125132|ref|WP_003034931|]
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MULTISPECIES: copper homeostasis membrane protein CopD [Citrobacter]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
copper_CopD NF033808
copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in ...
3-290 4.95e-93

copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in Gram-negative bacterial systems that provide resistance to excess copper. It is typically chromosomal, although the PcoD protein of the plasmid-borne pco copper resistance system is a exceptional member of the CopD family.


:

Pssm-ID: 468191  Cd Length: 295  Bit Score: 277.08  E-value: 4.95e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132   3 AFTWVALRFIHFTTLMLVFGCALYGAWLAPVSVRRLMMRRFLRLQRHAATWSFISATLMLAIQGGLMGSGWRDVISTDVW 82
Cdd:NF033808   1 DALLIALRFAHYLALMLLFGLALFGLYLLPGSLRALLRRRLLRLLRLAAVLGLLSSLLWLALQAAAMGGGWLDALDHTLW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  83 GAVLQTQFGGVWLWQIILALVTLVVVIIVPRSMPRRLLMLT-IAQFILLAGVGHATLHSGITGAIQQVNHALHLICAAAW 161
Cdd:NF033808  81 MVVLGTRFGQAWLWRLVALVLALLALLLLPRRPRRLLLALLgAVALATLAWTGHAAMDEGLLGVLHLLNDILHLLAAGAW 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132 162 FGGLLPVLYCMRMAH---GRWREQAISTMMRFSRYGHLFVIGVLLTGIMNALFIVGFSVPWHM---AYGRLLLLKGALVM 235
Cdd:NF033808 161 LGALLPLLLLLRRARlgrDAWRRLAIRALMRFSRVGHLAVALLIVTGVVNYLLIVGPWPLDWLsssTYGRLLLLKLALVA 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489125132 236 LMVAIALVNRYVLVPRMQQDNRGMTLYFIWMTKLEWGIGAVVLAIVSLFATLEPF 290
Cdd:NF033808 241 LMLGLALANRYRLVPRLERALRGALRALRRSTALELALGVLVLALVAWLGTLSPV 295
 
Name Accession Description Interval E-value
copper_CopD NF033808
copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in ...
3-290 4.95e-93

copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in Gram-negative bacterial systems that provide resistance to excess copper. It is typically chromosomal, although the PcoD protein of the plasmid-borne pco copper resistance system is a exceptional member of the CopD family.


Pssm-ID: 468191  Cd Length: 295  Bit Score: 277.08  E-value: 4.95e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132   3 AFTWVALRFIHFTTLMLVFGCALYGAWLAPVSVRRLMMRRFLRLQRHAATWSFISATLMLAIQGGLMGSGWRDVISTDVW 82
Cdd:NF033808   1 DALLIALRFAHYLALMLLFGLALFGLYLLPGSLRALLRRRLLRLLRLAAVLGLLSSLLWLALQAAAMGGGWLDALDHTLW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  83 GAVLQTQFGGVWLWQIILALVTLVVVIIVPRSMPRRLLMLT-IAQFILLAGVGHATLHSGITGAIQQVNHALHLICAAAW 161
Cdd:NF033808  81 MVVLGTRFGQAWLWRLVALVLALLALLLLPRRPRRLLLALLgAVALATLAWTGHAAMDEGLLGVLHLLNDILHLLAAGAW 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132 162 FGGLLPVLYCMRMAH---GRWREQAISTMMRFSRYGHLFVIGVLLTGIMNALFIVGFSVPWHM---AYGRLLLLKGALVM 235
Cdd:NF033808 161 LGALLPLLLLLRRARlgrDAWRRLAIRALMRFSRVGHLAVALLIVTGVVNYLLIVGPWPLDWLsssTYGRLLLLKLALVA 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489125132 236 LMVAIALVNRYVLVPRMQQDNRGMTLYFIWMTKLEWGIGAVVLAIVSLFATLEPF 290
Cdd:NF033808 241 LMLGLALANRYRLVPRLERALRGALRALRRSTALELALGVLVLALVAWLGTLSPV 295
PcoD COG1276
Putative copper export protein [Inorganic ion transport and metabolism];
80-289 1.10e-35

Putative copper export protein [Inorganic ion transport and metabolism];


Pssm-ID: 440887  Cd Length: 282  Bit Score: 129.41  E-value: 1.10e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  80 DVWGAVL-QTQFGGVWLWQIILALVTLVVVIIVPRSMPRRLLM--LTIAQFILLAGVGHATLHSGItgAIQQVNHALHLI 156
Cdd:COG1276    1 AALLAVLtQTSFGRAWLVRLLLAALLALLLLLAVRSRAGAALLllLALLALLTLALTGHAAASEGH--ALAVLADALHLL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132 157 CAAAWFGGLLPVLYCMRMAHGRwrEQAISTMMRFSRYGHLFVIGVLLTGIMNALFIVG-FSVPWHMAYGRLLLLKGALVM 235
Cdd:COG1276   79 AAAVWVGGLLALLLLLRRLRRG--AALAAALRRFSRLALVAVALLALSGVVNAWLRLGsLSALLTTPYGRLLLAKLALVA 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489125132 236 LMVAIALVNRYVLVPRMQQDNRGMTLyFIWMTKLEWGIGAVVLAIVSLFATLEP 289
Cdd:COG1276  157 VLLALAALNRRRLVPRLEAGPRALRR-LRRSIRAELVLGLLVLGLAAALATTPP 209
CopD pfam05425
Copper resistance protein D; Copper sequestering activity displayed by some bacteria is ...
192-284 6.61e-12

Copper resistance protein D; Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm.


Pssm-ID: 428466 [Multi-domain]  Cd Length: 96  Bit Score: 60.71  E-value: 6.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  192 RYGHLFVIGVLLTGIMNALFIVGFSVPWHMAYGRLLLLKGALVMLMVAIALVNRYVLVPRMQQ---DNRGMTLYFIWMTK 268
Cdd:pfam05425   1 RLALAAVAALLLTGVVNALLRVGLGGLLTTAYGQLLLAKLALVLLLLALAALNRFRLVPRLRArgaGGRALRRRLRRSVR 80
                          90
                  ....*....|....*.
gi 489125132  269 LEWGIGAVVLAIVSLF 284
Cdd:pfam05425  81 LELVLGLVVLGLAAVL 96
 
Name Accession Description Interval E-value
copper_CopD NF033808
copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in ...
3-290 4.95e-93

copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in Gram-negative bacterial systems that provide resistance to excess copper. It is typically chromosomal, although the PcoD protein of the plasmid-borne pco copper resistance system is a exceptional member of the CopD family.


Pssm-ID: 468191  Cd Length: 295  Bit Score: 277.08  E-value: 4.95e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132   3 AFTWVALRFIHFTTLMLVFGCALYGAWLAPVSVRRLMMRRFLRLQRHAATWSFISATLMLAIQGGLMGSGWRDVISTDVW 82
Cdd:NF033808   1 DALLIALRFAHYLALMLLFGLALFGLYLLPGSLRALLRRRLLRLLRLAAVLGLLSSLLWLALQAAAMGGGWLDALDHTLW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  83 GAVLQTQFGGVWLWQIILALVTLVVVIIVPRSMPRRLLMLT-IAQFILLAGVGHATLHSGITGAIQQVNHALHLICAAAW 161
Cdd:NF033808  81 MVVLGTRFGQAWLWRLVALVLALLALLLLPRRPRRLLLALLgAVALATLAWTGHAAMDEGLLGVLHLLNDILHLLAAGAW 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132 162 FGGLLPVLYCMRMAH---GRWREQAISTMMRFSRYGHLFVIGVLLTGIMNALFIVGFSVPWHM---AYGRLLLLKGALVM 235
Cdd:NF033808 161 LGALLPLLLLLRRARlgrDAWRRLAIRALMRFSRVGHLAVALLIVTGVVNYLLIVGPWPLDWLsssTYGRLLLLKLALVA 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489125132 236 LMVAIALVNRYVLVPRMQQDNRGMTLYFIWMTKLEWGIGAVVLAIVSLFATLEPF 290
Cdd:NF033808 241 LMLGLALANRYRLVPRLERALRGALRALRRSTALELALGVLVLALVAWLGTLSPV 295
PcoD COG1276
Putative copper export protein [Inorganic ion transport and metabolism];
80-289 1.10e-35

Putative copper export protein [Inorganic ion transport and metabolism];


Pssm-ID: 440887  Cd Length: 282  Bit Score: 129.41  E-value: 1.10e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  80 DVWGAVL-QTQFGGVWLWQIILALVTLVVVIIVPRSMPRRLLM--LTIAQFILLAGVGHATLHSGItgAIQQVNHALHLI 156
Cdd:COG1276    1 AALLAVLtQTSFGRAWLVRLLLAALLALLLLLAVRSRAGAALLllLALLALLTLALTGHAAASEGH--ALAVLADALHLL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132 157 CAAAWFGGLLPVLYCMRMAHGRwrEQAISTMMRFSRYGHLFVIGVLLTGIMNALFIVG-FSVPWHMAYGRLLLLKGALVM 235
Cdd:COG1276   79 AAAVWVGGLLALLLLLRRLRRG--AALAAALRRFSRLALVAVALLALSGVVNAWLRLGsLSALLTTPYGRLLLAKLALVA 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489125132 236 LMVAIALVNRYVLVPRMQQDNRGMTLyFIWMTKLEWGIGAVVLAIVSLFATLEP 289
Cdd:COG1276  157 VLLALAALNRRRLVPRLEAGPRALRR-LRRSIRAELVLGLLVLGLAAALATTPP 209
CopD pfam05425
Copper resistance protein D; Copper sequestering activity displayed by some bacteria is ...
192-284 6.61e-12

Copper resistance protein D; Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm.


Pssm-ID: 428466 [Multi-domain]  Cd Length: 96  Bit Score: 60.71  E-value: 6.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125132  192 RYGHLFVIGVLLTGIMNALFIVGFSVPWHMAYGRLLLLKGALVMLMVAIALVNRYVLVPRMQQ---DNRGMTLYFIWMTK 268
Cdd:pfam05425   1 RLALAAVAALLLTGVVNALLRVGLGGLLTTAYGQLLLAKLALVLLLLALAALNRFRLVPRLRArgaGGRALRRRLRRSVR 80
                          90
                  ....*....|....*.
gi 489125132  269 LEWGIGAVVLAIVSLF 284
Cdd:pfam05425  81 LELVLGLVVLGLAAVL 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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