|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11860 |
PRK11860 |
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase; |
1-424 |
0e+00 |
|
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
Pssm-ID: 237003 [Multi-domain] Cd Length: 661 Bit Score: 600.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTRceIIGNGG 80
Cdd:PRK11860 4 TEFLDLPPLLSAGGTVRLPGSKSISNRVLLLAALSEGTTTVRDLLDSDDTRVMLDALRALGCGVEQLGDTYR--ITGLGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALhAQGSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGG--FT 158
Cdd:PRK11860 82 QF-PVKQADLFLGNAGTAMRPLTAALALLGGEYELSGVPRMHERPIGDLVDALRQLGCDIDYLGNEGFPPLRIGPAplRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 159 GGQVEVDGSVSSQFLTALLMTAPL-APQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPGAY 237
Cdd:PRK11860 161 DAPIRVRGDVSSQFLTALLMALPLvARRDITIEVVGELISKPYIEITLNLLARFGIAVQREGWQRFTIPAGSRYRSPGEI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 238 LVEGDASSASYFLAAGAIKGGT-VKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRGE--LNAVDMDMNHIPDA 314
Cdd:PRK11860 241 HVEGDASSASYFIAAGAIAGGApVRIEGVGRDSIQGDIRFAEAARAMGAQVTSGPNWLEVRRGAwpLKAIDLDCNHIPDA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 315 AMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPA---TLQFADIATYNDHRMAMCF 391
Cdd:PRK11860 321 AMTLAVMALYADGTTTLRNIASWRVKETDRIAAMATELRKLGATVEEGADYIRVTPPAqaaDWKAAAIHTYDDHRMAMCF 400
|
410 420 430
....*....|....*....|....*....|....*
gi 489125971 392 SLVAL--SDTPVTILDPKCTAKTFPDYFEQLARIS 424
Cdd:PRK11860 401 SLAAFnpAGLPVRINDPKCVAKTFPDYFEALFSVA 435
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
1-423 |
0e+00 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 593.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSaDRTRCEIIGNGG 80
Cdd:COG0128 1 MSSLTIAPPSPLKGTVRVPGSKSISHRALLLAALAEGESTIRNLLESDDTLATLEALRALGAEIEEL-DGGTLRVTGVGG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALHAQgSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEqENYPPLRLRGG-FTG 159
Cdd:COG0128 80 GLKEP-DAVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQLGARIESRG-GGYLPLTIRGGpLKG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 160 GQVEVDGSVSSQFLTALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQsPGAYLV 239
Cdd:COG0128 158 GEYEIPGSASSQFKSALLLAGPLAEGGLEITVTGELESKPYRDHTERMLRAFGVEVEVEGYRRFTVPGGQRYR-PGDYTV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 240 EGDASSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRGELNAVDMDMNHIPDAAMTIA 319
Cdd:COG0128 237 PGDISSAAFFLAAAAITGSEVTVEGVGLNSTQGDTGILDILKEMGADIEIENDGITVRGSPLKGIDIDLSDIPDEAPTLA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 320 TAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SD 398
Cdd:COG0128 317 VLAAFAEGTTRIRGAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGPKLKGAEVDSYGDHRIAMAFAVAGLrAE 396
|
410 420
....*....|....*....|....*
gi 489125971 399 TPVTILDPKCTAKTFPDYFEQLARI 423
Cdd:COG0128 397 GPVTIDDAECVAKSFPDFFELLESL 421
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
12-423 |
0e+00 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 551.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 12 VDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSAdrTRCEIIGNGGALHAQGSVELF 91
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDKD--GVITIQGVGMAGLKAPQNALN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 92 LGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTGGQVEVDGSVSSQ 171
Cdd:cd01554 79 LGNSGTAIRLISGVLAGADFEVELFGDDSLSKRPMDRVTLPLKKMGASISGQEERDLPPLLKGGKNLGPIHYEDPIASAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 172 FLTALLMTAPLAPQDTTIAIKgdlVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPgAYLVEGDASSASYFLA 251
Cdd:cd01554 159 VKSALMFAALLAKGETVIIEA---AKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQ-KYVVPGDISSAAFFLV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 252 AGAIKGGTVKVTGIGRNSmqGDIRFADVLEKMGATITWGNDFIACTRGELNAVDMDMNHIP---DAAMTIATAALFAKGT 328
Cdd:cd01554 235 AAAIAPGRLVLQNVGINE--TRTGIIDVLRAMGAKIEIGEDTISVESSDLKATEICGALIPrliDELPIIALLALQAQGT 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 329 TTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SDTPVTILDPK 407
Cdd:cd01554 313 TVIKDAEELKVKETDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTFGDHRIGMMTALAALvADGEVELDRAE 392
|
410
....*....|....*.
gi 489125971 408 CTAKTFPDYFEQLARI 423
Cdd:cd01554 393 AINTSYPSFFDDLESL 408
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
14-423 |
4.58e-160 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 457.12 E-value: 4.58e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 14 GTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTrcEIIGNGGAlhaQGSVELFLG 93
Cdd:TIGR01356 1 GEIRAPGSKSITHRALILAALAEGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVA--VIEGVGGK---EPQAELDLG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 94 NAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTGGQVEVDGSVSSQFL 173
Cdd:TIGR01356 76 NSGTTARLLTGVLALADGEVVLTGDESLRKRPMGRLVDALRQLGAEISSLEGGGSLPLTISGPLPGGIVYISGSASSQYK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 174 TALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPGaYLVEGDASSASYFLAAG 253
Cdd:TIGR01356 156 SALLLAAPALQAVGITIVGEPLKSRPYIEITLDLLGSFGVEVERSDGRKIVVPGGQKYGPQG-YDVPGDYSSAAFFLAAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 254 AIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRG-ELNAVDMDMNHIPDAAMTIATAALFAKGTTTLR 332
Cdd:TIGR01356 235 AITGGRVTLENLGINPTQGDKAIIIVLEEMGADIEVEEDDLIVEGAsGLKGIKIDMDDMIDELPTLAVLAAFAEGVTRIT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 333 NIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SDTPVTILDPKCTAK 411
Cdd:TIGR01356 315 GAEELRVKESDRIAAIAEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTFGDHRIAMAFAVAGLvAEGEVLIDDPECVAK 394
|
410
....*....|..
gi 489125971 412 TFPDYFEQLARI 423
Cdd:TIGR01356 395 SFPSFFDVLERL 406
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-420 |
1.17e-159 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 456.37 E-value: 1.17e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 7 QPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGIS-YTLSADRTRCEIIGNGGALHAQ 85
Cdd:pfam00275 1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEiIKLDDEKSVVIVEGLGGSFEAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 86 GSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGfTGGQVEVD 165
Cdd:pfam00275 81 EDLVLDMGNSGTALRPLTGRLALQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPLKVRGL-RLGGIHID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 166 GSVSSQFLTALLMTAPLAPQDTTIaIKGdLVSKPYIDITLNLMKTFGVEIENQNY-QRFVVKGQQqyQSPGA-YLVEGDA 243
Cdd:pfam00275 160 GDVSSQFVTSLLMLAALLAEGTTT-IEN-LASEPYIDDTENMLKKFGAKIEGSGTeLSITVKGGE--KLPGQeYRVEGDR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 244 SSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDF-IACTRGELNAVDMDMNHIPDAAMTIATAA 322
Cdd:pfam00275 236 SSAAYFLVAAAITGGTVTVENVGINSLQGDEALLEILEKMGAEITQEEDAdIVVGPPGLRGKAVDIRTAPDPAPTTAVLA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 323 LFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPA-TLQFADIATYNDHRMAMCFSLVAL-SDTP 400
Cdd:pfam00275 316 AFAEGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYGDHRIAMALALAGLvAEGE 395
|
410 420
....*....|....*....|
gi 489125971 401 VTILDPKCTAKTFPDYFEQL 420
Cdd:pfam00275 396 TIIDDIECTDRSFPDFEEKL 415
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11860 |
PRK11860 |
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase; |
1-424 |
0e+00 |
|
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
Pssm-ID: 237003 [Multi-domain] Cd Length: 661 Bit Score: 600.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTRceIIGNGG 80
Cdd:PRK11860 4 TEFLDLPPLLSAGGTVRLPGSKSISNRVLLLAALSEGTTTVRDLLDSDDTRVMLDALRALGCGVEQLGDTYR--ITGLGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALhAQGSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGG--FT 158
Cdd:PRK11860 82 QF-PVKQADLFLGNAGTAMRPLTAALALLGGEYELSGVPRMHERPIGDLVDALRQLGCDIDYLGNEGFPPLRIGPAplRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 159 GGQVEVDGSVSSQFLTALLMTAPL-APQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPGAY 237
Cdd:PRK11860 161 DAPIRVRGDVSSQFLTALLMALPLvARRDITIEVVGELISKPYIEITLNLLARFGIAVQREGWQRFTIPAGSRYRSPGEI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 238 LVEGDASSASYFLAAGAIKGGT-VKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRGE--LNAVDMDMNHIPDA 314
Cdd:PRK11860 241 HVEGDASSASYFIAAGAIAGGApVRIEGVGRDSIQGDIRFAEAARAMGAQVTSGPNWLEVRRGAwpLKAIDLDCNHIPDA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 315 AMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPA---TLQFADIATYNDHRMAMCF 391
Cdd:PRK11860 321 AMTLAVMALYADGTTTLRNIASWRVKETDRIAAMATELRKLGATVEEGADYIRVTPPAqaaDWKAAAIHTYDDHRMAMCF 400
|
410 420 430
....*....|....*....|....*....|....*
gi 489125971 392 SLVAL--SDTPVTILDPKCTAKTFPDYFEQLARIS 424
Cdd:PRK11860 401 SLAAFnpAGLPVRINDPKCVAKTFPDYFEALFSVA 435
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
1-423 |
0e+00 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 593.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSaDRTRCEIIGNGG 80
Cdd:COG0128 1 MSSLTIAPPSPLKGTVRVPGSKSISHRALLLAALAEGESTIRNLLESDDTLATLEALRALGAEIEEL-DGGTLRVTGVGG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALHAQgSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEqENYPPLRLRGG-FTG 159
Cdd:COG0128 80 GLKEP-DAVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQLGARIESRG-GGYLPLTIRGGpLKG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 160 GQVEVDGSVSSQFLTALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQsPGAYLV 239
Cdd:COG0128 158 GEYEIPGSASSQFKSALLLAGPLAEGGLEITVTGELESKPYRDHTERMLRAFGVEVEVEGYRRFTVPGGQRYR-PGDYTV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 240 EGDASSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRGELNAVDMDMNHIPDAAMTIA 319
Cdd:COG0128 237 PGDISSAAFFLAAAAITGSEVTVEGVGLNSTQGDTGILDILKEMGADIEIENDGITVRGSPLKGIDIDLSDIPDEAPTLA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 320 TAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SD 398
Cdd:COG0128 317 VLAAFAEGTTRIRGAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGPKLKGAEVDSYGDHRIAMAFAVAGLrAE 396
|
410 420
....*....|....*....|....*
gi 489125971 399 TPVTILDPKCTAKTFPDYFEQLARI 423
Cdd:COG0128 397 GPVTIDDAECVAKSFPDFFELLESL 421
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
1-424 |
0e+00 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 579.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYtlsaDRTRCEIIGNGG 80
Cdd:PRK02427 2 MMMLLIIPPSPLSGTVRVPGSKSISHRALLLAALAEGETTITNLLRSEDTLATLNALRALGVEI----EDDEVVVEGVGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALHAQGSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYlEQENYPPLRLRGGFTGG 160
Cdd:PRK02427 78 GGLKEPEDVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQMGAKIEG-RDEGYLPLTIRGGKKGG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 161 QVEVDGSVSSQFLTALLMTAPL-APQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQ---NYQRFVVKGQQQYQsPGA 236
Cdd:PRK02427 157 PIEYDGPVSSQFVKSLLLLAPLfAEGDTETTVIEPLPSRPHTEITLRMLRAFGVEVENVegwGYRRIVIKGGQRLR-GQD 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 237 YLVEGDASSASYFLAAGAIKGG-TVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDF--------IACTRGELNAVDMD 307
Cdd:PRK02427 236 ITVPGDPSSAAFFLAAAAITGGsEVTITNVGLNSTQGGKAIIDVLEKMGADIEIENEReggepvgdIRVRSSELKGIDID 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 308 MNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLqfADIATYNDHRM 387
Cdd:PRK02427 316 IPDIIDEAPTLAVLAAFAEGTTVIRNAEELRVKETDRIAAMATELRKLGAEVEETEDGLIITGGPLA--GVVDSYGDHRI 393
|
410 420 430
....*....|....*....|....*....|....*...
gi 489125971 388 AMCFSLVAL-SDTPVTILDPKCTAKTFPDYFEQLARIS 424
Cdd:PRK02427 394 AMAFAIAGLaAEGPVTIDDPECVAKSFPDFFEDLASLG 431
|
|
| PLN02338 |
PLN02338 |
3-phosphoshikimate 1-carboxyvinyltransferase |
1-425 |
0e+00 |
|
3-phosphoshikimate 1-carboxyvinyltransferase
Pssm-ID: 177972 [Multi-domain] Cd Length: 443 Bit Score: 557.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTRCEIIGNGG 80
Cdd:PLN02338 1 AEEITLQPIKEISGTVKLPGSKSLSNRILLLAALSEGTTVVDNLLDSDDIRYMLGALKTLGLNVEEDSENNRAVVEGCGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 AL----HAQGSVELFLGNAGTAMRPLAAALCL--GSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRL- 153
Cdd:PLN02338 81 KFpvsgDSKEDVELFLGNAGTAMRPLTAAVTAagGNASYVLDGVPRMRERPIGDLVDGLKQLGADVECTLGTNCPPVRVn 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 154 -RGGFTGGQVEVDGSVSSQFLTALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQN-YQRFVVKGQQQY 231
Cdd:PLN02338 161 aAGGLPGGKVKLSGSISSQYLTALLMAAPLALGDVEIEIVDKLISVPYVEMTLKLMERFGVSVEHSDsWDRFFIKGGQKY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 232 QSPGAYLVEGDASSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTR--------GELNA 303
Cdd:PLN02338 241 KSPGNAYVEGDASSASYFLAGAAITGGTVTVEGCGTTSLQGDVKFAEVLEKMGAKVEWTENSVTVTGpprdafggKHLKA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 304 VDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYN 383
Cdd:PLN02338 321 IDVNMNKMPDVAMTLAVVALFADGPTAIRDVASWRVKETERMIAICTELRKLGATVEEGPDYCIITPPKKLKPAEIDTYD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 489125971 384 DHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARIST 425
Cdd:PLN02338 401 DHRMAMAFSLAACGDVPVTINDPGCTRKTFPTYFDVLESIAK 442
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
12-423 |
0e+00 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 551.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 12 VDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSAdrTRCEIIGNGGALHAQGSVELF 91
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDKD--GVITIQGVGMAGLKAPQNALN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 92 LGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTGGQVEVDGSVSSQ 171
Cdd:cd01554 79 LGNSGTAIRLISGVLAGADFEVELFGDDSLSKRPMDRVTLPLKKMGASISGQEERDLPPLLKGGKNLGPIHYEDPIASAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 172 FLTALLMTAPLAPQDTTIAIKgdlVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPgAYLVEGDASSASYFLA 251
Cdd:cd01554 159 VKSALMFAALLAKGETVIIEA---AKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQ-KYVVPGDISSAAFFLV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 252 AGAIKGGTVKVTGIGRNSmqGDIRFADVLEKMGATITWGNDFIACTRGELNAVDMDMNHIP---DAAMTIATAALFAKGT 328
Cdd:cd01554 235 AAAIAPGRLVLQNVGINE--TRTGIIDVLRAMGAKIEIGEDTISVESSDLKATEICGALIPrliDELPIIALLALQAQGT 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 329 TTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SDTPVTILDPK 407
Cdd:cd01554 313 TVIKDAEELKVKETDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTFGDHRIGMMTALAALvADGEVELDRAE 392
|
410
....*....|....*.
gi 489125971 408 CTAKTFPDYFEQLARI 423
Cdd:cd01554 393 AINTSYPSFFDDLESL 408
|
|
| EPSP_synthase |
cd01556 |
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ... |
12-423 |
0e+00 |
|
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.
Pssm-ID: 238797 Cd Length: 409 Bit Score: 541.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 12 VDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRtrCEIIGNGGALHAQgSVELF 91
Cdd:cd01556 1 LSGEITVPGSKSISHRALLLAALAEGESRIENLLDSDDTLATLEALRALGAKIEEEGGT--VEIVGGGGLGLPP-EAVLD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 92 LGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTGGQVEVDGSVSSQ 171
Cdd:cd01556 78 CGNSGTTMRLLTGLLALQGGDSVLTGDESLRKRPMGRLVDALRQLGAEIEGREGGGYPPLIGGGGLKGGEVEIPGAVSSQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 172 FLTALLMTAPLAPQDTTIaIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPgAYLVEGDASSASYFLA 251
Cdd:cd01556 158 FKSALLLAAPLAEGPTTI-IIGELESKPYIDHTERMLRAFGAEVEVDGYRTITVKGGQKYKGP-EYTVEGDASSAAFFLA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 252 AGAIKGGTVKVTGIGRNSmqGDIRFADVLEKMGATITWGN-DFIACTR-GELNAVDMDMNHIPDAAMTIATAALFAKGTT 329
Cdd:cd01556 236 AAAITGSEIVIKNVGLNS--GDTGIIDVLKEMGADIEIGNeDTVVVESgGKLKGIDIDGNDIPDEAPTLAVLAAFAEGPT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 330 TLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITP-PATLQFADIATYNDHRMAMCFSLVAL-SDTPVTILDPK 407
Cdd:cd01556 314 RIRNAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGgPLKGAGVEVYTYGDHRIAMSFAIAGLvAEGGVTIEDPE 393
|
410
....*....|....*.
gi 489125971 408 CTAKTFPDYFEQLARI 423
Cdd:cd01556 394 CVAKSFPNFFEDLESL 409
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
14-423 |
4.58e-160 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 457.12 E-value: 4.58e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 14 GTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTrcEIIGNGGAlhaQGSVELFLG 93
Cdd:TIGR01356 1 GEIRAPGSKSITHRALILAALAEGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVA--VIEGVGGK---EPQAELDLG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 94 NAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTGGQVEVDGSVSSQFL 173
Cdd:TIGR01356 76 NSGTTARLLTGVLALADGEVVLTGDESLRKRPMGRLVDALRQLGAEISSLEGGGSLPLTISGPLPGGIVYISGSASSQYK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 174 TALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPGaYLVEGDASSASYFLAAG 253
Cdd:TIGR01356 156 SALLLAAPALQAVGITIVGEPLKSRPYIEITLDLLGSFGVEVERSDGRKIVVPGGQKYGPQG-YDVPGDYSSAAFFLAAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 254 AIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIACTRG-ELNAVDMDMNHIPDAAMTIATAALFAKGTTTLR 332
Cdd:TIGR01356 235 AITGGRVTLENLGINPTQGDKAIIIVLEEMGADIEVEEDDLIVEGAsGLKGIKIDMDDMIDELPTLAVLAAFAEGVTRIT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 333 NIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQFADIATYNDHRMAMCFSLVAL-SDTPVTILDPKCTAK 411
Cdd:TIGR01356 315 GAEELRVKESDRIAAIAEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTFGDHRIAMAFAVAGLvAEGEVLIDDPECVAK 394
|
410
....*....|..
gi 489125971 412 TFPDYFEQLARI 423
Cdd:TIGR01356 395 SFPSFFDVLERL 406
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-420 |
1.17e-159 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 456.37 E-value: 1.17e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 7 QPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGIS-YTLSADRTRCEIIGNGGALHAQ 85
Cdd:pfam00275 1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEiIKLDDEKSVVIVEGLGGSFEAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 86 GSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGfTGGQVEVD 165
Cdd:pfam00275 81 EDLVLDMGNSGTALRPLTGRLALQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPLKVRGL-RLGGIHID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 166 GSVSSQFLTALLMTAPLAPQDTTIaIKGdLVSKPYIDITLNLMKTFGVEIENQNY-QRFVVKGQQqyQSPGA-YLVEGDA 243
Cdd:pfam00275 160 GDVSSQFVTSLLMLAALLAEGTTT-IEN-LASEPYIDDTENMLKKFGAKIEGSGTeLSITVKGGE--KLPGQeYRVEGDR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 244 SSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDF-IACTRGELNAVDMDMNHIPDAAMTIATAA 322
Cdd:pfam00275 236 SSAAYFLVAAAITGGTVTVENVGINSLQGDEALLEILEKMGAEITQEEDAdIVVGPPGLRGKAVDIRTAPDPAPTTAVLA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 323 LFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPA-TLQFADIATYNDHRMAMCFSLVAL-SDTP 400
Cdd:pfam00275 316 AFAEGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYGDHRIAMALALAGLvAEGE 395
|
410 420
....*....|....*....|
gi 489125971 401 VTILDPKCTAKTFPDYFEQL 420
Cdd:pfam00275 396 TIIDDIECTDRSFPDFEEKL 415
|
|
| PRK11861 |
PRK11861 |
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
1-426 |
1.03e-153 |
|
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 183343 [Multi-domain] Cd Length: 673 Bit Score: 450.70 E-value: 1.03e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 1 MESLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISytLSADRTRCEIIGNGG 80
Cdd:PRK11861 240 MEHLDLGPFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVK--LSRDGGTCVVGGTRG 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 81 ALHAQgSVELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFTG- 159
Cdd:PRK11861 318 AFTAK-TADLFLGNAGTAVRPLTAALAVNGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNEGFPPLRIRPATISv 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 160 -GQVEVDGSVSSQFLTALLMTAPLAPQD---TTIAIKGDLVSKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQSPG 235
Cdd:PRK11861 397 dAPIRVRGDVSSQFLTALLMTLPLVKAKdgaSVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFTVPAGVRYRSPG 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 236 AYLVEGDASSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGNDFIAC-----TRGELNAVDMDMNH 310
Cdd:PRK11861 477 TIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIEVrgighDHGRLAPIDMDFNL 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 311 IPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPATLQ-FADIATYNDHRMAM 389
Cdd:PRK11861 557 IPDAAMTIAVAALFADGPSTLRNIGSWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTpNASIDTYDDHRMAM 636
|
410 420 430
....*....|....*....|....*....|....*..
gi 489125971 390 CFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISTS 426
Cdd:PRK11861 637 CFSLVSLGGVPVRINDPKCVGKTFPDYFDRFLALANA 673
|
|
| EPT_RTPC-like |
cd01553 |
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate ... |
240-423 |
5.30e-57 |
|
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a 4th slightly different domain inserted between the 2nd and 3rd repeat. They evidently share the same active site location, although the catalytic residues differ.
Pssm-ID: 238794 Cd Length: 211 Bit Score: 186.72 E-value: 5.30e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 240 EGDASSASYFLAAGAIKGGTVKVTGIGRNSM-----QGDIRFADVLEKM-GATITWGN---DFIACTRGELNAVDMDMNH 310
Cdd:cd01553 7 KGGGQILRSFLVLAAISGGPITVTGIRPDRAkpgllRQHLTFLKALEKIcGATVEGGElgsDRISFRPGTVRGGDVRFAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 311 -----IPDAAMTIATAALFAKGTTTLRNIYNWRV----KETDRLFAMATELRKVGAEVEEGHD------------FIRIT 369
Cdd:cd01553 87 gsagsCTDVLQTILPLLLFAKGPTRLTVTGGTDNpsapPADFIRFVLEPELAKIGAHQEETLLrhgfypagggvvATEVS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 489125971 370 PPATLQFADIatyndhRMAMCFSLVAlsdTPVTILDPKCTAKTFPDYFEQLARI 423
Cdd:cd01553 167 PVEKLNTAQL------RQLVLPMLLA---SGAVEFTVAHPSCHLLTNFAVLEAL 211
|
|
| PRK14806 |
PRK14806 |
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ... |
3-422 |
2.33e-38 |
|
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 237820 [Multi-domain] Cd Length: 735 Bit Score: 147.45 E-value: 2.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 3 SLTLQPIARVDGTINLPGSKSVSNRALLLAALANGTTVLTNLLDSDDVRHMLNALNVLGISYT-LSADRTRCEIIGNGGA 81
Cdd:PRK14806 303 SYSVLPGGAVKGTIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEgPHNGRVTIHGVGLHGL 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 82 LHAQGSveLFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKIDyLEQENYPPLRLRGGFTGGQ 161
Cdd:PRK14806 383 KAPPGP--LYMGNSGTSMRLLSGLLAAQSFDSVLTGDASLSKRPMERVAKPLREMGAVIE-TGEEGRPPLSIRGGQRLKG 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 162 VEVDGSV-SSQFLTALLMTAPLAPQDTTiaikgdlVSKPYI--DITLNLMKTFGVEIEnqnyqrfvVKGQQQYQSPGAYL 238
Cdd:PRK14806 460 IHYDLPMaSAQVKSCLLLAGLYAEGETS-------VTEPAPtrDHTERMLRGFGYPVK--------VEGNTISVEGGGKL 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 239 ------VEGDASSASYFLAAGAIKGGT-VKVTGIGRNSMQgdIRFADVLEKMGATITWGNDFIActRGE------LNAVD 305
Cdd:PRK14806 525 tatdieVPADISSAAFFLVAASIAEGSeLTLEHVGINPTR--TGVIDILKLMGADITLENEREV--GGEpvadirVRGAR 600
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 306 MDMNHIPDAAMTIA--------TAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITpPATLQFA 377
Cdd:PRK14806 601 LKGIDIPEDQVPLAidefpvlfVAAACAEGRTVLTGAEELRVKESDRIQVMADGLKTLGIDCEPTPDGIIIE-GGIFGGG 679
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 489125971 378 DIATYNDHRMAMCFSLVAL-SDTPVTILDPKCTAKTFPDyFEQLAR 422
Cdd:PRK14806 680 EVESHGDHRIAMSFSVASLrASGPITIHDCANVATSFPN-FLELAN 724
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
36-363 |
1.61e-09 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 59.23 E-value: 1.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 36 NGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTrCEIigNGGALHaqgSVELFLGNAGTaMRplAAALCLGSndivL 115
Cdd:COG0766 36 DGPVTLRNVPDLSDVRTMLELLESLGVKVERDDGGT-LTI--DASNIN---STEAPYELVRK-MR--ASILVLGP----L 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 116 TGepRMKE-------------RPIG-HLvDALRQGGAKIDYlEQENYpplRLR-GGFTGGQVEVDG-SVssqflTA---L 176
Cdd:COG0766 103 LA--RFGEarvslpggcaigaRPIDlHL-KGLEALGAEIEI-EHGYI---EARaGRLKGARIYLDFpSV-----GAtenI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 177 LMTAPLAPQDTTI---AIKgdlvskPYID--IT-LNLMktfGVEIENQNYQRFVVKGQQQYqSPGAYLVEGD---ASSas 247
Cdd:COG0766 171 MMAAVLAEGTTVIenaARE------PEIVdlANfLNAM---GAKIEGAGTDTITIEGVEKL-HGAEHTVIPDrieAGT-- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 248 yFLAAGAIKGGTVKVTGIGRNSMQGdirFADVLEKMGATITWGNDFIACTR-GELNAVDM----------DMNHIpdaAM 316
Cdd:COG0766 239 -FLVAAAITGGDVTVKNVIPEHLEA---VLAKLREAGVEIEEGDDGIRVRGpGRLKAVDIktapypgfptDLQAQ---FM 311
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 489125971 317 TIATaalFAKGTTTLR-NIYNWRvketdrlFAMATELRKVGAEVE-EGH 363
Cdd:COG0766 312 ALLT---QAEGTSVITeTVFENR-------FMHVDELNRMGADIKlDGH 350
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
36-405 |
4.36e-07 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 51.71 E-value: 4.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 36 NGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTrCEIIgnggALHAQgSVELFLGNAGTaMRplAAALCLGsndiVL 115
Cdd:cd01555 25 DEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGENT-LVID----ASNIN-STEAPYELVRK-MR--ASILVLG----PL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 116 TGepRMKE-------------RPIG-HLVdALRQGGAKIDylEQENYPPLRLRGGFTGGQVEVD-GSVssqflTA---LL 177
Cdd:cd01555 92 LA--RFGEarvslpggcaigaRPVDlHLK-GLEALGAKIE--IEDGYVEAKAAGRLKGARIYLDfPSV-----GAtenIM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 178 MTAPLAPQDTTI---AIkgdlvsKPYIDITLNLMKTFGVEIENQNYQRFVVKGQQQYQsPGAYLVEGDASSASYFLAAGA 254
Cdd:cd01555 162 MAAVLAEGTTVIenaAR------EPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLH-GAEHTVIPDRIEAGTFLVAAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 255 IKGGTVKVTGIGRNSMqgdIRFADVLEKMGATITWGNDFIACTR--GELNAVDMDMNHIP----DAAMTIATAALFAKGT 328
Cdd:cd01555 235 ITGGDITVENVIPEHL---EAVLAKLREMGAKIEIGEDGIRVDGdgGRLKAVDIETAPYPgfptDLQAQFMALLTQAEGT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 329 TTLR-NIYNWRvketdrlFAMATELRKVGAEVE-EGHDFIrITPPATLQFADI-ATynDHRMAMCFSLVALSDTPVTILD 405
Cdd:cd01555 312 SVITeTIFENR-------FMHVDELNRMGADIKvEGNTAI-IRGVTKLSGAPVmAT--DLRAGAALVLAGLAAEGETIIS 381
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
277-381 |
6.03e-06 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 48.06 E-value: 6.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 277 ADVLEKMGATITW-GNDFIACT-RGELNAVDMDMnhIPD--AAMTIATAALFAKGTTTLRNIynwrvkETDRLFAMATEL 352
Cdd:COG0766 196 ANFLNAMGAKIEGaGTDTITIEgVEKLHGAEHTV--IPDriEAGTFLVAAAITGGDVTVKNV------IPEHLEAVLAKL 267
|
90 100
....*....|....*....|....*....
gi 489125971 353 RKVGAEVEEGHDFIRITPPATLQFADIAT 381
Cdd:COG0766 268 REAGVEIEEGDDGIRVRGPGRLKAVDIKT 296
|
|
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
36-363 |
4.05e-05 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 45.41 E-value: 4.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 36 NGTTVLTNLLDSDDVRHMLNALNVLGISYTLSADRTRceIIGNGGALHAQGSVELflgnAGTaMRplAAALCLGsndivl 115
Cdd:PRK09369 36 EEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNGTV--TIDASNINNTEAPYEL----VKK-MR--ASILVLG------ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 116 tgeP---RMKE-------------RPIG-HLvDALRQGGAKIDylEQENYPPLRLRGGFTGGQVEVDG-SVssqflTA-- 175
Cdd:PRK09369 101 ---PllaRFGEakvslpggcaigaRPVDlHL-KGLEALGAEIE--IEHGYVEAKADGRLKGAHIVLDFpSV-----GAte 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 176 -LLMTAPLAPQDTTI---AIKgdlvskPYI-DIT--LNLMktfGVEIENQNYQRFVVKGQQQYqSPGAYLVEGDASSASY 248
Cdd:PRK09369 170 nILMAAVLAEGTTVIenaARE------PEIvDLAnfLNKM---GAKISGAGTDTITIEGVERL-HGAEHTVIPDRIEAGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 249 FLAAGAIKGGTVKVTGIGRNSMQGdirFADVLEKMGATITWGNDFIACTR-GELNAVDM----------DMNhipdaAMT 317
Cdd:PRK09369 240 FLVAAAITGGDVTIRGARPEHLEA---VLAKLREAGAEIEEGEDGIRVDMpGRLKAVDIktapypgfptDMQ-----AQF 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 489125971 318 IATAALfAKGTTTlrniynwrVKET---DRLFaMATELRKVGAEVE-EGH 363
Cdd:PRK09369 312 MALLTQ-AEGTSV--------ITETifeNRFM-HVPELIRMGADIEvDGH 351
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
160-369 |
1.10e-04 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 44.00 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 160 GQVEVDGSVSSqfLTALLMTAPLAPQDTTI----AIKgDlvskpyIDITLNLMKTFGVEIENQNYQRFVV--KGQQQYQS 233
Cdd:cd01555 3 GEVRISGAKNA--ALPILAAALLTDEPVTLrnvpDLL-D------VETMIELLRSLGAKVEFEGENTLVIdaSNINSTEA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 234 PGAYlvegdASS--ASyFLAAGAI--KGGTVKVTG-----IGRnsmqgdiRFAD----VLEKMGATITWGNDFI-ACTRG 299
Cdd:cd01555 74 PYEL-----VRKmrAS-ILVLGPLlaRFGEARVSLpggcaIGA-------RPVDlhlkGLEALGAKIEIEDGYVeAKAAG 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489125971 300 ELNAVDMDMNHIPDAA-MTIATAALFAKGTTTLRNIYnwrvKE---TDrlfaMATELRKVGAEVE-EGHDFIRIT 369
Cdd:cd01555 141 RLKGARIYLDFPSVGAtENIMMAAVLAEGTTVIENAA----REpeiVD----LANFLNKMGAKIEgAGTDTIRIE 207
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
278-369 |
8.53e-04 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 41.51 E-value: 8.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 278 DVLEKMGATITWGNDFIACTRGELNAVDMDMnhipD-----AAMTIATAALFAKGTTTLRNIynwrvketdrlfamATE- 351
Cdd:COG0766 129 KGLEALGAEIEIEHGYIEARAGRLKGARIYL----DfpsvgATENIMMAAVLAEGTTVIENA--------------AREp 190
|
90 100
....*....|....*....|....*..
gi 489125971 352 --------LRKVGAEVE-EGHDFIRIT 369
Cdd:COG0766 191 eivdlanfLNAMGAKIEgAGTDTITIE 217
|
|
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
277-381 |
2.41e-03 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 40.01 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489125971 277 ADVLEKMGATIT-WGNDFIacT-RG--ELNAVDmdmnH--IPD---AAmTIATAALFAKGTTTLRNIynwrvkETDRLFA 347
Cdd:PRK09369 197 ANFLNKMGAKISgAGTDTI--TiEGveRLHGAE----HtvIPDrieAG-TFLVAAAITGGDVTIRGA------RPEHLEA 263
|
90 100 110
....*....|....*....|....*....|....
gi 489125971 348 MATELRKVGAEVEEGHDFIRITPPATLQFADIAT 381
Cdd:PRK09369 264 VLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKT 297
|
|
| |
