NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|489174468|ref|WP_003084001|]
View 

MULTISPECIES: malonate decarboxylase subunit delta [Pseudomonas]

Protein Classification

malonate decarboxylase acyl carrier protein( domain architecture ID 10011644)

malonate decarboxylase acyl carrier protein is a subunit of malonate decarboxylase, which catalyzes the decarboxylation of malonate to acetate and carbon dioxide

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK01220 PRK01220
malonate decarboxylase subunit delta; Provisional
 1-99 1.11e-61

malonate decarboxylase subunit delta; Provisional


:

Pssm-ID: 179253  Cd Length: 99  Bit Score: 182.48  E-value: 1.11e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468  1 METLTFEFPAGAPARGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDFGA 80
Cdd:PRK01220  1 METLTFEFPAGQPPRGRALVGVVGSGDLEVLLEPGDAGKLSIQVVTSVNGSAARWKALFERFFTAQTPPAANIDIHDFGA 80

                        90
                ....*....|....*....
gi 489174468 81 TPGVVRLRLEQALEEAGHD 99
Cdd:PRK01220 81 TPGVVRLRLEQALEEIGHD 99
 
Name Accession Description Interval E-value
PRK01220 PRK01220
malonate decarboxylase subunit delta; Provisional
 1-99 1.11e-61

malonate decarboxylase subunit delta; Provisional


Pssm-ID: 179253  Cd Length: 99  Bit Score: 182.48  E-value: 1.11e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468  1 METLTFEFPAGAPARGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDFGA 80
Cdd:PRK01220  1 METLTFEFPAGQPPRGRALVGVVGSGDLEVLLEPGDAGKLSIQVVTSVNGSAARWKALFERFFTAQTPPAANIDIHDFGA 80

                        90
                ....*....|....*....
gi 489174468 81 TPGVVRLRLEQALEEAGHD 99
Cdd:PRK01220 81 TPGVVRLRLEQALEEIGHD 99
malonate_delta TIGR03130
malonate decarboxylase acyl carrier protein; Members of this protein family are the acyl ...
 2-96 1.05e-46

malonate decarboxylase acyl carrier protein; Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.


Pssm-ID: 188283  Cd Length: 98  Bit Score: 144.74  E-value: 1.05e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468   2 ETLTFEFPAGAPARGR--ALAGCVGSGDLEVLLEP-AAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDF 78
Cdd:TIGR03130  1 ETLTFEFPAQAPARGKapALVGVVGSGDLEVLVEPgALGGKTEVQIVTSVDGFDAVWQAVLERFFARYPLAGLQIEINDF 80

                         90
                 ....*....|....*...
gi 489174468  79 GATPGVVRLRLEQALEEA 96
Cdd:TIGR03130 81 GATPAVVSLRLRQALEEL 98
ACP pfam06857
Malonate decarboxylase delta subunit (MdcD); This family consists of several bacterial ...
 15-96 3.26e-31

Malonate decarboxylase delta subunit (MdcD); This family consists of several bacterial malonate decarboxylase delta subunit (MdcD) proteins. Malonate decarboxylase of Klebsiella pneumoniae consists of four different subunits and catalyzes the conversion of malonate plus H+ to acetate and CO2. The catalysis proceeds via acetyl and malonyl thioester residues with the phosphribosyl-dephospho-CoA prosthetic group of the acyl carrier protein (ACP) subunit. MdcC is the (apo) ACP subunit. The family also contains the CitD family of citrate lyase acyl carrier proteins.


Pssm-ID: 429157  Cd Length: 83  Bit Score: 104.89  E-value: 3.26e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468  15 RGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSV-NGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQAL 93
Cdd:pfam06857  1 KKTALAGTLESSDLEVTVEPALGGGIEIELESSVaKQFGDQIRAVIEETLEELGVKDAKVTINDKGALDCVIRARLEQAL 80


                 ...
gi 489174468  94 EEA 96
Cdd:pfam06857 81 ERA 83
CitD COG3052
Acyl-carrier protein (citrate lyase gamma subunit) [Energy production and conversion];
17-97 5.85e-23

Acyl-carrier protein (citrate lyase gamma subunit) [Energy production and conversion];


Pssm-ID: 442286  Cd Length: 91  Bit Score: 84.45  E-value: 5.85e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468 17 RALAGCVGSGDLEVLLEPAAGGALSIQVVTSV-NGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQALEE 95
Cdd:COG3052   6 EAVAGTLESSDLMVTVEPADGGGIEIELTSSVeKQFGDQIRAVVRETLARLGVTGAKVIIEDKGALDCVIRARLETALER 85


                ..
gi 489174468 96 AG 97
Cdd:COG3052  86 AL 87
 
Name Accession Description Interval E-value
PRK01220 PRK01220
malonate decarboxylase subunit delta; Provisional
 1-99 1.11e-61

malonate decarboxylase subunit delta; Provisional


Pssm-ID: 179253  Cd Length: 99  Bit Score: 182.48  E-value: 1.11e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468  1 METLTFEFPAGAPARGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDFGA 80
Cdd:PRK01220  1 METLTFEFPAGQPPRGRALVGVVGSGDLEVLLEPGDAGKLSIQVVTSVNGSAARWKALFERFFTAQTPPAANIDIHDFGA 80

                        90
                ....*....|....*....
gi 489174468 81 TPGVVRLRLEQALEEAGHD 99
Cdd:PRK01220 81 TPGVVRLRLEQALEEIGHD 99
malonate_delta TIGR03130
malonate decarboxylase acyl carrier protein; Members of this protein family are the acyl ...
 2-96 1.05e-46

malonate decarboxylase acyl carrier protein; Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.


Pssm-ID: 188283  Cd Length: 98  Bit Score: 144.74  E-value: 1.05e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468   2 ETLTFEFPAGAPARGR--ALAGCVGSGDLEVLLEP-AAGGALSIQVVTSVNGSGPRWQQLFARVFAASTAPAASIRIHDF 78
Cdd:TIGR03130  1 ETLTFEFPAQAPARGKapALVGVVGSGDLEVLVEPgALGGKTEVQIVTSVDGFDAVWQAVLERFFARYPLAGLQIEINDF 80

                         90
                 ....*....|....*...
gi 489174468  79 GATPGVVRLRLEQALEEA 96
Cdd:TIGR03130 81 GATPAVVSLRLRQALEEL 98
ACP pfam06857
Malonate decarboxylase delta subunit (MdcD); This family consists of several bacterial ...
 15-96 3.26e-31

Malonate decarboxylase delta subunit (MdcD); This family consists of several bacterial malonate decarboxylase delta subunit (MdcD) proteins. Malonate decarboxylase of Klebsiella pneumoniae consists of four different subunits and catalyzes the conversion of malonate plus H+ to acetate and CO2. The catalysis proceeds via acetyl and malonyl thioester residues with the phosphribosyl-dephospho-CoA prosthetic group of the acyl carrier protein (ACP) subunit. MdcC is the (apo) ACP subunit. The family also contains the CitD family of citrate lyase acyl carrier proteins.


Pssm-ID: 429157  Cd Length: 83  Bit Score: 104.89  E-value: 3.26e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468  15 RGRALAGCVGSGDLEVLLEPAAGGALSIQVVTSV-NGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQAL 93
Cdd:pfam06857  1 KKTALAGTLESSDLEVTVEPALGGGIEIELESSVaKQFGDQIRAVIEETLEELGVKDAKVTINDKGALDCVIRARLEQAL 80


                 ...
gi 489174468  94 EEA 96
Cdd:pfam06857 81 ERA 83
CitD COG3052
Acyl-carrier protein (citrate lyase gamma subunit) [Energy production and conversion];
17-97 5.85e-23

Acyl-carrier protein (citrate lyase gamma subunit) [Energy production and conversion];


Pssm-ID: 442286  Cd Length: 91  Bit Score: 84.45  E-value: 5.85e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468 17 RALAGCVGSGDLEVLLEPAAGGALSIQVVTSV-NGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQALEE 95
Cdd:COG3052   6 EAVAGTLESSDLMVTVEPADGGGIEIELTSSVeKQFGDQIRAVVRETLARLGVTGAKVIIEDKGALDCVIRARLETALER 85


                ..
gi 489174468 96 AG 97
Cdd:COG3052  86 AL 87
PRK02103 PRK02103
malonate decarboxylase acyl carrier protein;
1-94 5.70e-19

malonate decarboxylase acyl carrier protein;


Pssm-ID: 179367  Cd Length: 105  Bit Score: 74.69  E-value: 5.70e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468   1 METLTFEFPAGAPARGR---ALAGCVGSGDLEVLLEPAA-GGALSIQVVTSVNGSGPRWQQLFARvFAASTAPAA-SIRI 75
Cdd:PRK02103   1 METLNYRFTARRRAKGAraaALVGVVASGNLEVLVERVLpGGECEVEIRTAAVGFGAVWQAVVAD-FVERRSPGGlRISI 79

                         90
                 ....*....|....*....
gi 489174468  76 HDFGATPGVVRLRLEQALE 94
Cdd:PRK02103  80 NDGGARPDTVSLRLAQAVR 98
PRK13253 PRK13253
citrate lyase subunit gamma; Provisional
 18-96 3.06e-03

citrate lyase subunit gamma; Provisional


Pssm-ID: 237316  Cd Length: 92  Bit Score: 33.67  E-value: 3.06e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489174468 18 ALAGCVGSGDLEVLLEPAAGGALSIQVVTSV-NGSGPRWQQLFARVFAASTAPAASIRIHDFGATPGVVRLRLEQALEEA 96
Cdd:PRK13253  7 AVAGTLESSDVMIRIAPADTQGIDIQLESSVeKQFGDQIRAVILETLAKLGVENAQVKVDDKGALDCVIRARLEAAVLRA 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH