|
Name |
Accession |
Description |
Interval |
E-value |
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
37-301 |
2.52e-16 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 77.75 E-value: 2.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 37 TSIVLPAGARYPNGIAHAADGTLYVGLVTSGRILRK-PPGGEWETFFAGSPAifAATALRLDePRGLLWgnspdflpAGR 115
Cdd:COG4257 8 TEYPVPAPGSGPRDVAVDPDGAVWFTDQGGGRIGRLdPATGEFTEYPLGGGS--GPHGIAVD-PDGNLW--------FTD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 116 RRPHGVFALDLASGAVRRYlTLPGDGMG-NDLAVAPDGTVYLSETRDGSLMRLRPGEPAFQVLlrdsrLAGPGGLGAAGI 194
Cdd:COG4257 77 NGNNRIGRIDPKTGEITTF-ALPGGGSNpHGIAFDPDGNLWFTDQGGNRIGRLDPATGEVTEF-----PLPTGGAGPYGI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 195 VRVDDDTLLVGNFGSGAIHVVEgvATRPRLREMELPRTLENPDGMALAPDGSLIVLENA------IRSGAGKVLRIAEPL 268
Cdd:COG4257 151 AVDPDGNLWVTDFGANAIGRID--PDTGTLTEYALPTPGAGPRGLAVDPDGNLWVADTGsgrigrFDPKTGTVTEYPLPG 228
|
250 260 270
....*....|....*....|....*....|...
gi 489178241 269 APGRrgievireglesPVNLTVTGQGCAYVSES 301
Cdd:COG4257 229 GGAR------------PYGVAVDGDGRVWFAES 249
|
|
| NHL_PKND_like |
cd14952 |
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein ... |
39-300 |
3.37e-06 |
|
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein with a cytosolic kinase domain and an extracellular sensor domain that contains NHL repeats. It plays a key role in the development of central nervous system tuberculosis, by mediating the invasion of host brain endothelia. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271322 [Multi-domain] Cd Length: 247 Bit Score: 47.59 E-value: 3.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 39 IVLP-AGARYPNGIAHAADGTLYVGLVTSGRILRKPPGgewetffAGSPAIFAATAlrLDEPRGLLWGNSPD--FLPAGR 115
Cdd:cd14952 2 TVLPfTGLDGPGGVAVDAAGNVYVADSGNNRVLKLAAG-------STTQTVLPFTG--LYQPQGVAVDAAGTvyVTDFGN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 116 RRphgvfALDLASGAVRRyLTLPGDGMGN--DLAVAPDGTVYLSETRDGSLMRLRPGEPAFQVL----LRDSRLagpggl 189
Cdd:cd14952 73 NR-----VLKLAAGSTTQ-TVLPFTGLNDptGVAVDAAGNVYVADTGNNRVLKLAAGSNTQTVLpftgLSNPDG------ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 190 gaagiVRVDD-DTLLVGNFGSGAIHVVEGVATRPRlremELPRT-LENPDGMALAPDGSLIVLEnairSGAGKVLRiaep 267
Cdd:cd14952 141 -----VAVDGaGNVYVTDTGNNRVLKLAAGSTTQT----VLPFTgLNSPSGVAVDTAGNVYVTD----HGNNRVLK---- 203
|
250 260 270
....*....|....*....|....*....|....
gi 489178241 268 LAPGRRGIEVIR-EGLESPVNLTVTGQGCAYVSE 300
Cdd:cd14952 204 LAAGSTTPTVLPfTGLNGPLGVAVDAAGNVYVAD 237
|
|
| SGL |
pfam08450 |
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ... |
51-265 |
6.40e-05 |
|
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Pssm-ID: 462480 [Multi-domain] Cd Length: 246 Bit Score: 43.79 E-value: 6.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 51 IAHAADGTLYVGLvTSGRILRKPPGGEWETFFAGSPAifAATALRLDE----PRGLLWGNSPDFLPAGRRRPHGVFALDL 126
Cdd:pfam08450 46 IAPRDDGGLIVAL-KDGVALLDLATGELTPLADPEDD--DWPLNRFNDgkvdPDGRFWFGTMGDDEAPGGDPGALYRLDP 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 127 ASGAVRryltlPGDGMG--NDLAVAPDG-TVYLSETRDGSLMrlrpgepAFqvllrdsrlagpgglgaagivRVDDDTLL 203
Cdd:pfam08450 123 DGKLTR-----VLDGLTisNGLAWSPDGrTLYFADSPARKIW-------AY---------------------DYDLDGGL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489178241 204 VGNfgsgaihvvegvatRPRLREMelPRTLENPDGMALAPDGSLIVlenaIRSGAGKVLRIA 265
Cdd:pfam08450 170 ISN--------------RRVFADF--KPGLGRPDGMAVDAEGNVWV----ARWGGGKVVRFD 211
|
|
| ScyE_fam |
NF033206 |
ScyD/ScyE family protein; This family includes ScyE, a protein involved in scytomenin ... |
235-299 |
9.64e-04 |
|
ScyD/ScyE family protein; This family includes ScyE, a protein involved in scytomenin biosynthesis and export, and its paralog ScyD. Some members of the family contain a C-terminal PEP-CTERM domain that predictions anchoring to the outer membrane.
Pssm-ID: 467996 [Multi-domain] Cd Length: 330 Bit Score: 40.34 E-value: 9.64e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 235 NPDGMALAPDGSLIVLENA-----IRSGAGKVLRIAeplAPGRRgiEVIREGLESPVNLTVTGQGCAYVS 299
Cdd:NF033206 251 GLTDLAFDPDGNLYVLELAgggllKGDPTGSLIRIA---PDGTR--TTLLDGLELPTGLAVGPDGTLYVT 315
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
37-301 |
2.52e-16 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 77.75 E-value: 2.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 37 TSIVLPAGARYPNGIAHAADGTLYVGLVTSGRILRK-PPGGEWETFFAGSPAifAATALRLDePRGLLWgnspdflpAGR 115
Cdd:COG4257 8 TEYPVPAPGSGPRDVAVDPDGAVWFTDQGGGRIGRLdPATGEFTEYPLGGGS--GPHGIAVD-PDGNLW--------FTD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 116 RRPHGVFALDLASGAVRRYlTLPGDGMG-NDLAVAPDGTVYLSETRDGSLMRLRPGEPAFQVLlrdsrLAGPGGLGAAGI 194
Cdd:COG4257 77 NGNNRIGRIDPKTGEITTF-ALPGGGSNpHGIAFDPDGNLWFTDQGGNRIGRLDPATGEVTEF-----PLPTGGAGPYGI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 195 VRVDDDTLLVGNFGSGAIHVVEgvATRPRLREMELPRTLENPDGMALAPDGSLIVLENA------IRSGAGKVLRIAEPL 268
Cdd:COG4257 151 AVDPDGNLWVTDFGANAIGRID--PDTGTLTEYALPTPGAGPRGLAVDPDGNLWVADTGsgrigrFDPKTGTVTEYPLPG 228
|
250 260 270
....*....|....*....|....*....|...
gi 489178241 269 APGRrgievireglesPVNLTVTGQGCAYVSES 301
Cdd:COG4257 229 GGAR------------PYGVAVDGDGRVWFAES 249
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
40-265 |
1.63e-15 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 75.31 E-value: 1.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 40 VLPAGARYPNGIAHAADGTLYVGLVTSGRILR-KPPGGEWETFFAGSPaifAATALRLDEPRGLLwgnspdflpAGRRRp 118
Cdd:COG3386 2 LADAGFRLGEGPVWDPDGRLYWVDIPGGRIHRyDPDGGAVEVFAEPSG---RPNGLAFDPDGRLL---------VADHG- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 119 HGVFALDLASGAVRRYLTLPGDGMG--NDLAVAPDGTVYLS----ETRDGSLMRLRPGEpAFQVLLRDsrlagpgglgaa 192
Cdd:COG3386 69 RGLVRFDPADGEVTVLADEYGKPLNrpNDGVVDPDGRLYFTdmgeYLPTGALYRVDPDG-SLRVLADG------------ 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 193 gIVRV-------DDDTLLVGNFGSGAIHVVEgVATRPRLREMELPRTLE----NPDGMALAPDGSLIVLENairsGAGKV 261
Cdd:COG3386 136 -LTFPngiafspDGRTLYVADTGAGRIYRFD-LDADGTLGNRRVFADLPdgpgGPDGLAVDADGNLWVALW----GGGGV 209
|
....
gi 489178241 262 LRIA 265
Cdd:COG3386 210 VRFD 213
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
37-231 |
1.67e-12 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 66.58 E-value: 1.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 37 TSIVLPAGARYPNGIAHAADGTLYVGLVTSGRILR-KPPGGEWETFFAGSPAIFaATALRLDePRGLLWgnspdflpAGR 115
Cdd:COG4257 93 TTFALPGGGSNPHGIAFDPDGNLWFTDQGGNRIGRlDPATGEVTEFPLPTGGAG-PYGIAVD-PDGNLW--------VTD 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 116 RRPHGVFALDLASGAVRRYlTLPGDGMG-NDLAVAPDGTVYLSETRDGSLMRLRPGEPAFQVLlrdsrLAGPGGLGAAGI 194
Cdd:COG4257 163 FGANAIGRIDPDTGTLTEY-ALPTPGAGpRGLAVDPDGNLWVADTGSGRIGRFDPKTGTVTEY-----PLPGGGARPYGV 236
|
170 180 190
....*....|....*....|....*....|....*..
gi 489178241 195 VRVDDDTLLVGNFGSGAIHVvegVATRPRLREMELPR 231
Cdd:COG4257 237 AVDGDGRVWFAESGANRIVR---FDPDTELTEYVLPS 270
|
|
| NHL_PKND_like |
cd14952 |
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein ... |
39-300 |
3.37e-06 |
|
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein with a cytosolic kinase domain and an extracellular sensor domain that contains NHL repeats. It plays a key role in the development of central nervous system tuberculosis, by mediating the invasion of host brain endothelia. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271322 [Multi-domain] Cd Length: 247 Bit Score: 47.59 E-value: 3.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 39 IVLP-AGARYPNGIAHAADGTLYVGLVTSGRILRKPPGgewetffAGSPAIFAATAlrLDEPRGLLWGNSPD--FLPAGR 115
Cdd:cd14952 2 TVLPfTGLDGPGGVAVDAAGNVYVADSGNNRVLKLAAG-------STTQTVLPFTG--LYQPQGVAVDAAGTvyVTDFGN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 116 RRphgvfALDLASGAVRRyLTLPGDGMGN--DLAVAPDGTVYLSETRDGSLMRLRPGEPAFQVL----LRDSRLagpggl 189
Cdd:cd14952 73 NR-----VLKLAAGSTTQ-TVLPFTGLNDptGVAVDAAGNVYVADTGNNRVLKLAAGSNTQTVLpftgLSNPDG------ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 190 gaagiVRVDD-DTLLVGNFGSGAIHVVEGVATRPRlremELPRT-LENPDGMALAPDGSLIVLEnairSGAGKVLRiaep 267
Cdd:cd14952 141 -----VAVDGaGNVYVTDTGNNRVLKLAAGSTTQT----VLPFTgLNSPSGVAVDTAGNVYVTD----HGNNRVLK---- 203
|
250 260 270
....*....|....*....|....*....|....
gi 489178241 268 LAPGRRGIEVIR-EGLESPVNLTVTGQGCAYVSE 300
Cdd:cd14952 204 LAAGSTTPTVLPfTGLNGPLGVAVDAAGNVYVAD 237
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
42-306 |
9.90e-06 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 46.16 E-value: 9.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 42 PAGARYPNGIAHAADGTLYVGLVTSGRILRKPPGGEWETFFAGspaiFAATALRLDEPRGLlwgnspDFLPAGRrrphgV 121
Cdd:cd05819 4 PGELNNPQGIAVDSSGNIYVADTGNNRIQVFDPDGNFITSFGS----FGSGDGQFNEPAGV------AVDSDGN-----L 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 122 FALDLASGAVRRY---------LTLPGDGMGN-----DLAVAPDGTVYLSETRDGSlmrlrpgepafqvllrdsrlagpg 187
Cdd:cd05819 69 YVADTGNHRIQKFdpdgnflasFGGSGDGDGEfngprGIAVDSSGNIYVADTGNHR------------------------ 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 188 glgaagIVRVDDDTLLVGNFGSGAihvvegvatrprlremELPRTLENPDGMALAPDGSLIVLEnairSGAGKVLRIA-- 265
Cdd:cd05819 125 ------IQKFDPDGEFLTTFGSGG----------------SGPGQFNGPTGVAVDSDGNIYVAD----TGNHRIQVFDpd 178
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 489178241 266 -EPLAP-GRRGIEVIRegLESPVNLTVTGQGCAYVSESRiRHR 306
Cdd:cd05819 179 gNFLTTfGSTGTGPGQ--FNYPTGIAVDSDGNIYVADSG-NNR 218
|
|
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
49-210 |
2.08e-05 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 46.14 E-value: 2.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 49 NGIAHAADGTLYV----GLVTSGRILRKPPGGEWETFFAGSPAIFAATALRLDePRGLLWGNSPDflpagrrrpHGVFAL 124
Cdd:COG3292 270 RSIAEDSDGNLWIrlwiGTYGGGLFRLDPKTGKFKRYNPNGLPSNSVYSILED-SDGNLWIGTSG---------GGLYRY 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 125 DLASGAVRRYLTLPG--DGMGNDLAVAPDGTVYLSeTRDGsLMRLRPGEPAFQVLLRDSRLAGPGGLGAAGIVRVDDDTL 202
Cdd:COG3292 340 DPKTGKFTKFSEDNGlsNNFIRSILEDSDGNLWVG-TNGG-LYRLDPKTGKFTNFTHDPDKNGLSSNYINSIFEDSDGRL 417
|
....*...
gi 489178241 203 LVGNFGSG 210
Cdd:COG3292 418 WIGTDGGG 425
|
|
| NHL_like_5 |
cd14963 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
46-159 |
3.55e-05 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271333 [Multi-domain] Cd Length: 268 Bit Score: 44.59 E-value: 3.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 46 RYPNGIAHAADGTLYVGLVTSGRILRKPPGGEWETFFAGSP---AIFAATALRLDEprgllwGNspdfLPAGRRRPHGVF 122
Cdd:cd14963 56 KYPYGIAVDSDGNIYVADLYNGRIQVFDPDGKFLKYFPEKKdrvKLISPAGLAIDD------GK----LYVSDVKKHKVI 125
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 489178241 123 ALDLaSGAVRRYLTLPGDGMG-----NDLAVAPDGTVYLSET 159
Cdd:cd14963 126 VFDL-EGKLLLEFGKPGSEPGelsypNGIAVDEDGNIYVADS 166
|
|
| SGL |
pfam08450 |
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ... |
51-265 |
6.40e-05 |
|
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Pssm-ID: 462480 [Multi-domain] Cd Length: 246 Bit Score: 43.79 E-value: 6.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 51 IAHAADGTLYVGLvTSGRILRKPPGGEWETFFAGSPAifAATALRLDE----PRGLLWGNSPDFLPAGRRRPHGVFALDL 126
Cdd:pfam08450 46 IAPRDDGGLIVAL-KDGVALLDLATGELTPLADPEDD--DWPLNRFNDgkvdPDGRFWFGTMGDDEAPGGDPGALYRLDP 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 127 ASGAVRryltlPGDGMG--NDLAVAPDG-TVYLSETRDGSLMrlrpgepAFqvllrdsrlagpgglgaagivRVDDDTLL 203
Cdd:pfam08450 123 DGKLTR-----VLDGLTisNGLAWSPDGrTLYFADSPARKIW-------AY---------------------DYDLDGGL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489178241 204 VGNfgsgaihvvegvatRPRLREMelPRTLENPDGMALAPDGSLIVlenaIRSGAGKVLRIA 265
Cdd:pfam08450 170 ISN--------------RRVFADF--KPGLGRPDGMAVDAEGNVWV----ARWGGGKVVRFD 211
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
47-304 |
3.16e-04 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 41.92 E-value: 3.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 47 YPNGIAHAADGTLYVGLVTSGRILRKPPGGEWETFFAGspaiFAATALRLDEPRGLlwgnspDFLPAGRrrphgVFALDL 126
Cdd:cd05819 56 EPAGVAVDSDGNLYVADTGNHRIQKFDPDGNFLASFGG----SGDGDGEFNGPRGI------AVDSSGN-----IYVADT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 127 ASGAVRRY-------LTLPGDGMGN-------DLAVAPDGTVYLSETRDGSlmrlrpgepafqvllrdsrlagpgglgaa 192
Cdd:cd05819 121 GNHRIQKFdpdgeflTTFGSGGSGPgqfngptGVAVDSDGNIYVADTGNHR----------------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 193 gIVRVDDDTLLVGNFGSGAIHvvegvatrprlremelPRTLENPDGMALAPDGSLIVLEnairSGAGKVLRI-AEPLAPG 271
Cdd:cd05819 172 -IQVFDPDGNFLTTFGSTGTG----------------PGQFNYPTGIAVDSDGNIYVAD----SGNNRVQVFdPDGAGFG 230
|
250 260 270
....*....|....*....|....*....|....*..
gi 489178241 272 RRG-IEVIREGLESPVNLTVTGQGCAYVSES---RIR 304
Cdd:cd05819 231 GNGnFLGSDGQFNRPSGLAVDSDGNLYVADTgnnRIQ 267
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
55-248 |
4.38e-04 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.22 E-value: 4.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 55 ADGTLYVGLVTSGRILRKPPGGEWETFFAGSPAIFAATALRLDEPRGLLWGNSPDFLPAGRRRPHGVFALDLASGAVRRY 134
Cdd:COG3391 26 AALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLATGKVVAT 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 135 LTLPGDGMGndLAVAPDG-TVYLSETRDGSLMRLRPgePAFQVLlrdsRLAGPGGLGAAGIVRVDDDTLLVGNFGSGAIH 213
Cdd:COG3391 106 IPVGGGPRG--LAVDPDGgRLYVADSGNGRVSVIDT--ATGKVV----ATIPVGAGPHGIAVDPDGKRLYVANSGSNTVS 177
|
170 180 190
....*....|....*....|....*....|....*
gi 489178241 214 VVEGVATRPRLREMELPRTLENPDGMALAPDGSLI 248
Cdd:COG3391 178 VIVSVIDTATGKVVATIPVGGGPVGVAVSPDGRRL 212
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
127-300 |
9.32e-04 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 40.39 E-value: 9.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 127 ASGAVRRYlTLPGDGMG-NDLAVAPDGTVYLSETRDGSLMRLRPGEPAFqvllrdsRLAGPGGLGAAGIVRVDDD-TLLV 204
Cdd:COG4257 3 SAVDITEY-PVPAPGSGpRDVAVDPDGAVWFTDQGGGRIGRLDPATGEF-------TEYPLGGGSGPHGIAVDPDgNLWF 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 205 GNFGSGAIHVV---EGVATRprlreMELPRTLENPDGMALAPDGSLIVLENairsGAGKVLRIaeplAPGRRGIEVIREG 281
Cdd:COG4257 75 TDNGNNRIGRIdpkTGEITT-----FALPGGGSNPHGIAFDPDGNLWFTDQ----GGNRIGRL----DPATGEVTEFPLP 141
|
170 180
....*....|....*....|.
gi 489178241 282 LE--SPVNLTVTGQGCAYVSE 300
Cdd:COG4257 142 TGgaGPYGIAVDPDGNLWVTD 162
|
|
| ScyE_fam |
NF033206 |
ScyD/ScyE family protein; This family includes ScyE, a protein involved in scytomenin ... |
235-299 |
9.64e-04 |
|
ScyD/ScyE family protein; This family includes ScyE, a protein involved in scytomenin biosynthesis and export, and its paralog ScyD. Some members of the family contain a C-terminal PEP-CTERM domain that predictions anchoring to the outer membrane.
Pssm-ID: 467996 [Multi-domain] Cd Length: 330 Bit Score: 40.34 E-value: 9.64e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 235 NPDGMALAPDGSLIVLENA-----IRSGAGKVLRIAeplAPGRRgiEVIREGLESPVNLTVTGQGCAYVS 299
Cdd:NF033206 251 GLTDLAFDPDGNLYVLELAgggllKGDPTGSLIRIA---PDGTR--TTLLDGLELPTGLAVGPDGTLYVT 315
|
|
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
51-181 |
1.06e-03 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 40.74 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 51 IAHAADGTLYVGLVTSGRILRKPPGGEWETF-FAGSPAIFAATALRLDePRGLLWgnspdflpAGRRrpHGVFALDLASG 129
Cdd:COG3292 319 ILEDSDGNLWIGTSGGGLYRYDPKTGKFTKFsEDNGLSNNFIRSILED-SDGNLW--------VGTN--GGLYRLDPKTG 387
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 489178241 130 AVRRYLTLPGDGMG-----NDLAVAPDGTVYLSeTRDGSLMRLRPGEPAFQVLLRDS 181
Cdd:COG3292 388 KFTNFTHDPDKNGLssnyiNSIFEDSDGRLWIG-TDGGGLYRYDPKTGKFKHFTTKD 443
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
42-159 |
2.26e-03 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 39.22 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489178241 42 PAGARYPNGIAHAADGTLYVGLVTSGRILRKPPGGEWETFFAGSPAIFAatalRLDEPRGLlwgnspDFLPAGRrrphgV 121
Cdd:cd05819 145 PGQFNGPTGVAVDSDGNIYVADTGNHRIQVFDPDGNFLTTFGSTGTGPG----QFNYPTGI------AVDSDGN-----I 209
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 489178241 122 FALDLASGAVRRY--LTLPGDGMGN------------DLAVAPDGTVYLSET 159
Cdd:cd05819 210 YVADSGNNRVQVFdpDGAGFGGNGNflgsdgqfnrpsGLAVDSDGNLYVADT 261
|
|
| |
