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Conserved domains on  [gi|489184907|ref|WP_003094334|]
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MULTISPECIES: BolA family protein [Gammaproteobacteria]

Protein Classification

BolA family protein( domain architecture ID 10009026)

BolA family potein similar to Escherichia coli acid stress protein IbaG, which undergoes altered expression in response to acidic stress and may impart acid resistance

CATH:  3.30.300.90
Gene Ontology:  GO:1990229|GO:0051537
SCOP:  4003220

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
1-79 1.07e-37

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


:

Pssm-ID: 444031  Cd Length: 81  Bit Score: 120.25  E-value: 1.07e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489184907  1 MQAEDVKSLLQEKLPGTQVEVEGEGCNFQLNLISDELAGQSPVKRQQQVYAHLNAWIADGSIHAVTMKFFSRAAWAERS 79
Cdd:COG5007   1 MTPEEIKQLIEAGLPCAEVEVEGDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASGEIHALSIKTYTPEEWAAQR 79
 
Name Accession Description Interval E-value
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
1-79 1.07e-37

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 120.25  E-value: 1.07e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489184907  1 MQAEDVKSLLQEKLPGTQVEVEGEGCNFQLNLISDELAGQSPVKRQQQVYAHLNAWIADGSIHAVTMKFFSRAAWAERS 79
Cdd:COG5007   1 MTPEEIKQLIEAGLPCAEVEVEGDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASGEIHALSIKTYTPEEWAAQR 79
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 10-68 8.29e-08

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 44.37  E-value: 8.29e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489184907  10 LQEKLPGTQVEVE---------GEGCN--FQLNLISDELAGQSPVKRQQQVYAHLNAWIADGsIHAVTMK 68
Cdd:pfam01722  1 LTEALAPTHLEVEdeshkhaghAGGGEthFKVVIVSDAFEGKSLVARHRLVYDALADELAGG-IHALSIK 69
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 23-77 4.24e-03

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 33.22  E-value: 4.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489184907  23 GEGCNFQLNLISDELAGQSPVKRQQQVYAHLNAWIAdGSIHAVTMKFFSRAAWAE 77
Cdd:PRK11628  34 GSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELS-TTVHALALHTYTIKEWEG 87
 
Name Accession Description Interval E-value
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
1-79 1.07e-37

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 120.25  E-value: 1.07e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489184907  1 MQAEDVKSLLQEKLPGTQVEVEGEGCNFQLNLISDELAGQSPVKRQQQVYAHLNAWIADGSIHAVTMKFFSRAAWAERS 79
Cdd:COG5007   1 MTPEEIKQLIEAGLPCAEVEVEGDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASGEIHALSIKTYTPEEWAAQR 79
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 3-78 2.73e-08

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 46.33  E-value: 2.73e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489184907  3 AEDVKSLLQEKLPGTQVEVE-------------GEGcNFQLNLISDELAGQSPVKRQQQVYAHLNAWIADGsIHAVTMKF 69
Cdd:COG0271   4 QERIEEKLTAALAPEHLEVIdeshlhaghagagGES-HFKVVIVSDAFAGKSRVARHRLVYAALADELAGG-IHALAIHA 81


                ....*....
gi 489184907 70 FSRAAWAER 78
Cdd:COG0271  82 YTPEEWQAR 90
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 10-68 8.29e-08

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 44.37  E-value: 8.29e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489184907  10 LQEKLPGTQVEVE---------GEGCN--FQLNLISDELAGQSPVKRQQQVYAHLNAWIADGsIHAVTMK 68
Cdd:pfam01722  1 LTEALAPTHLEVEdeshkhaghAGGGEthFKVVIVSDAFEGKSLVARHRLVYDALADELAGG-IHALSIK 69
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 23-77 4.24e-03

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 33.22  E-value: 4.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489184907  23 GEGCNFQLNLISDELAGQSPVKRQQQVYAHLNAWIAdGSIHAVTMKFFSRAAWAE 77
Cdd:PRK11628  34 GSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELS-TTVHALALHTYTIKEWEG 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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