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Conserved domains on  [gi|489185875|ref|WP_003095295|]
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MULTISPECIES: bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG [Pseudomonas]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 11454890)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008168|GO:1904047
PubMed:  12504684|12826405

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 44-160 1.77e-20

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


:

Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 84.30  E-value: 1.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  44 DETLAGVLRNLDLAGKAAVQVGCNNGREVLSLYAFGvARAVGIDQSAAFLAQARQLAERSPhqPRFVEANAYELPAElNG 123
Cdd:COG2227   11 DRRLAALLARLLPAGGRVLDVGCGTGRLALALARRG-ADVTGVDISPEALEIARERAAELN--VDFVQGDLEDLPLE-DG 86

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 489185875 124 QFDLLlITIGVLNWMPDIARFFASVSGLLKPGGQLAI 160
Cdd:COG2227   87 SFDLV-ICSEVLEHLPDPAALLRELARLLKPGGLLLL 122
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 44-160 1.77e-20

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 84.30  E-value: 1.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  44 DETLAGVLRNLDLAGKAAVQVGCNNGREVLSLYAFGvARAVGIDQSAAFLAQARQLAERSPhqPRFVEANAYELPAElNG 123
Cdd:COG2227   11 DRRLAALLARLLPAGGRVLDVGCGTGRLALALARRG-ADVTGVDISPEALEIARERAAELN--VDFVQGDLEDLPLE-DG 86

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 489185875 124 QFDLLlITIGVLNWMPDIARFFASVSGLLKPGGQLAI 160
Cdd:COG2227   87 SFDLV-ICSEVLEHLPDPAALLRELARLLKPGGLLLL 122
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 64-156 1.03e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 78.76  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERSPHQPRFVEANAYELPAElNGQFDlLLITIGVLNWM--PDI 141
Cdd:pfam13649   4 LGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEDLPFP-DGSFD-LVVSSGVLHHLpdPDL 81

                          90
                  ....*....|....*
gi 489185875  142 ARFFASVSGLLKPGG 156
Cdd:pfam13649  82 EAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 64-160 3.50e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 58.60  E-value: 3.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  64 VGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERSPHQP-RFVEANAYELPAELNGQFDLLLITIGVLNWMPDIA 142
Cdd:cd02440    5 LGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADNvEVLKGDAEELPPEADESFDVIISDPPLHHLVEDLA 84

                         90
                 ....*....|....*...
gi 489185875 143 RFFASVSGLLKPGGQLAI 160
Cdd:cd02440   85 RFLEEARRLLKPGGVLVL 102
PRK01683 PRK01683
trans-aconitate 2-methyltransferase; Provisional
 61-160 1.44e-09

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 234970  Cd Length: 258  Bit Score: 56.88  E-value: 1.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  61 AVQVGCNNGREV-LSLYAFGVARAVGIDQSAAFLAQARQlaeRSPHQpRFVEAN--AYELPAELNgqfdlLLITIGVLNW 137
Cdd:PRK01683  35 VVDLGCGPGNSTeLLVERWPAARITGIDSSPAMLAEARS---RLPDC-QFVEADiaSWQPPQALD-----LIFANASLQW 105

                         90       100
                 ....*....|....*....|...
gi 489185875 138 MPDIARFFASVSGLLKPGGQLAI 160
Cdd:PRK01683 106 LPDHLELFPRLVSLLAPGGVLAV 128
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 44-160 1.77e-20

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 84.30  E-value: 1.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  44 DETLAGVLRNLDLAGKAAVQVGCNNGREVLSLYAFGvARAVGIDQSAAFLAQARQLAERSPhqPRFVEANAYELPAElNG 123
Cdd:COG2227   11 DRRLAALLARLLPAGGRVLDVGCGTGRLALALARRG-ADVTGVDISPEALEIARERAAELN--VDFVQGDLEDLPLE-DG 86

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 489185875 124 QFDLLlITIGVLNWMPDIARFFASVSGLLKPGGQLAI 160
Cdd:COG2227   87 SFDLV-ICSEVLEHLPDPAALLRELARLLKPGGLLLL 122
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 64-165 5.03e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.81  E-value: 5.03e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  64 VGCNNGREVLSLYAFGvARAVGIDQSAAFLAQARQLAERSPHQPRFVEANAYELPAElNGQFDLLLITiGVLNWMPDIAR 143
Cdd:COG2226   29 LGCGTGRLALALAERG-ARVTGVDISPEMLELARERAAEAGLNVEFVVGDAEDLPFP-DGSFDLVISS-FVLHHLPDPER 105

                         90       100
                 ....*....|....*....|..
gi 489185875 144 FFASVSGLLKPGGQLAIYETHP 165
Cdd:COG2226  106 ALAEIARVLKPGGRLVVVDFSP 127
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 64-156 1.03e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 78.76  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERSPHQPRFVEANAYELPAElNGQFDlLLITIGVLNWM--PDI 141
Cdd:pfam13649   4 LGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEDLPFP-DGSFD-LVVSSGVLHHLpdPDL 81

                          90
                  ....*....|....*
gi 489185875  142 ARFFASVSGLLKPGG 156
Cdd:pfam13649  82 EAALREIARVLKPGG 96
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 64-160 3.60e-16

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 71.93  E-value: 3.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLYAFGvARAVGIDQSAAFLAQARQLAERSPHQprFVEANAYELPAElNGQFDLLLItIGVLNWMPDIAR 143
Cdd:pfam08241   3 VGCGTGLLTELLARLG-ARVTGVDISPEMLELAREKAPREGLT--FVVGDAEDLPFP-DNSFDLVLS-SEVLHHVEDPER 77

                          90
                  ....*....|....*..
gi 489185875  144 FFASVSGLLKPGGQLAI 160
Cdd:pfam08241  78 ALREIARVLKPGGILII 94
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
57-160 2.57e-15

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 69.85  E-value: 2.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  57 AGKAAVQVGCNNGREVLSLYA-FGVARAVGIDQSAAFLAQARQLAERSphqpRFVEANAYELPaeLNGQFDLLlITIGVL 135
Cdd:COG4106    1 PPRRVLDLGCGTGRLTALLAErFPGARVTGVDLSPEMLARARARLPNV----RFVVADLRDLD--PPEPFDLV-VSNAAL 73

                         90       100
                 ....*....|....*....|....*
gi 489185875 136 NWMPDIARFFASVSGLLKPGGQLAI 160
Cdd:COG4106   74 HWLPDHAALLARLAAALAPGGVLAV 98
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 64-158 3.24e-14

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 66.62  E-value: 3.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLYA-FGVARAVGIDQSAAFLAQARQ-LAERSPHQPRFVEANAYELPAELNGQFDLLLItIGVLNWMPDI 141
Cdd:pfam08242   3 IGCGTGTLLRALLEaLPGLEYTGLDISPAALEAARErLAALGLLNAVRVELFQLDLGELDPGSFDVVVA-SNVLHHLADP 81

                          90
                  ....*....|....*..
gi 489185875  142 ARFFASVSGLLKPGGQL 158
Cdd:pfam08242  82 RAVLRNIRRLLKPGGVL 98
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 45-160 9.46e-13

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 65.32  E-value: 9.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  45 ETLAGVLRNLDLAGKAaVQVGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERS-PHQPRFVEANAYELPAELNG 123
Cdd:COG0500   15 AALLALLERLPKGGRV-LDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAgLGNVEFLVADLAELDPLPAE 93

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 489185875 124 QFDLLLITiGVLNWMPDIAR--FFASVSGLLKPGGQLAI 160
Cdd:COG0500   94 SFDLVVAF-GVLHHLPPEEReaLLRELARALKPGGVLLL 131
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 64-160 3.50e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 58.60  E-value: 3.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  64 VGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERSPHQP-RFVEANAYELPAELNGQFDLLLITIGVLNWMPDIA 142
Cdd:cd02440    5 LGCGTGALALALASGPGARVTGVDISPVALELARKAAAALLADNvEVLKGDAEELPPEADESFDVIISDPPLHHLVEDLA 84

                         90
                 ....*....|....*...
gi 489185875 143 RFFASVSGLLKPGGQLAI 160
Cdd:cd02440   85 RFLEEARRLLKPGGVLVL 102
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 64-160 6.77e-11

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 59.17  E-value: 6.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  64 VGCNNGRevLSLYA---FGVaRAVGIDQSAAFLAQARQLAERS--PHQPRFVEANAYELPAElnGQFDLLlITIGVLNWM 138
Cdd:COG2230   58 IGCGWGG--LALYLarrYGV-RVTGVTLSPEQLEYARERAAEAglADRVEVRLADYRDLPAD--GQFDAI-VSIGMFEHV 131

                         90       100
                 ....*....|....*....|....
gi 489185875 139 PD--IARFFASVSGLLKPGGQLAI 160
Cdd:COG2230  132 GPenYPAYFAKVARLLKPGGRLLL 155
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
15-160 1.08e-09

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 56.16  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  15 WDASADSHLRGSGWQELslavqetgfscLDETLAgvlRNLDLAGKAAVQVGCNNGR--EVLSLYAFgvaRAVGIDQSAAF 92
Cdd:COG4976   18 YDAALVEDLGYEAPALL-----------AEELLA---RLPPGPFGRVLDLGCGTGLlgEALRPRGY---RLTGVDLSEEM 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489185875  93 LAQARqlaeRSPHQPRFVEANAYELPaELNGQFDLLLITiGVLNWMPDIARFFASVSGLLKPGGQLAI 160
Cdd:COG4976   81 LAKAR----EKGVYDRLLVADLADLA-EPDGRFDLIVAA-DVLTYLGDLAAVFAGVARALKPGGLFIF 142
PRK01683 PRK01683
trans-aconitate 2-methyltransferase; Provisional
 61-160 1.44e-09

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 234970  Cd Length: 258  Bit Score: 56.88  E-value: 1.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  61 AVQVGCNNGREV-LSLYAFGVARAVGIDQSAAFLAQARQlaeRSPHQpRFVEAN--AYELPAELNgqfdlLLITIGVLNW 137
Cdd:PRK01683  35 VVDLGCGPGNSTeLLVERWPAARITGIDSSPAMLAEARS---RLPDC-QFVEADiaSWQPPQALD-----LIFANASLQW 105

                         90       100
                 ....*....|....*....|...
gi 489185875 138 MPDIARFFASVSGLLKPGGQLAI 160
Cdd:PRK01683 106 LPDHLELFPRLVSLLAPGGVLAV 128
PRK08317 PRK08317
hypothetical protein; Provisional
 50-163 3.38e-09

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 55.71  E-value: 3.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  50 VLRNLDL-AGKAAVQVGCNNGREVLSLyAFGV---ARAVGIDQSAAFLAQARQLAERSPHQPRFVEANAYELPAElNGQF 125
Cdd:PRK08317  11 TFELLAVqPGDRVLDVGCGPGNDAREL-ARRVgpeGRVVGIDRSEAMLALAKERAAGLGPNVEFVRGDADGLPFP-DGSF 88

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 489185875 126 DLLLITiGVLNWMPDIARFFASVSGLLKPGGQLAIYET 163
Cdd:PRK08317  89 DAVRSD-RVLQHLEDPARALAEIARVLRPGGRVVVLDT 125
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 81-164 3.53e-09

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 55.54  E-value: 3.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  81 ARAVGIDQSAAFLAQARQ-LAERSPHQP-RFVEANAYELPAElNGQFDLLLITIGVLNwMPDIARFFASVSGLLKPGGQL 158
Cdd:PRK00216  77 GEVVGLDFSEGMLAVGREkLRDLGLSGNvEFVQGDAEALPFP-DNSFDAVTIAFGLRN-VPDIDKALREMYRVLKPGGRL 154


                 ....*.
gi 489185875 159 AIYETH 164
Cdd:PRK00216 155 VILEFS 160
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 64-188 3.38e-08

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 51.65  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLY--AFGVARAVGIDQSAAFLAQARQLAERSPHQP-RFVEANAYELPAELNGQ-FDLLlITIGVLNWMP 139
Cdd:pfam13847  10 LGCGTGHLSFELAeeLGPNAEVVGIDISEEAIEKARENAQKLGFDNvEFEQGDIEELPELLEDDkFDVV-ISNCVLNHIP 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 489185875  140 DIARFFASVSGLLKPGGQLAIYETHPFLEMLEPESERPFELRNDYFTDT 188
Cdd:pfam13847  89 DPDKVLQEILRVLKPGGRLIISDPDSLAELPAHVKEDSTYYAGCVGGAI 137
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
55-170 3.02e-07

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 50.13  E-value: 3.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   55 DLAGKAAVQVGCNNGRevlslYAFGVARAVG-------IDQSAAFLAQARQLAER-SPHQPRFVEANAYELPAElNGQFD 126
Cdd:pfam01209  40 VKRGNKFLDVAGGTGD-----WTFGLSDSAGssgkvvgLDINENMLKEGEKKAKEeGKYNIEFLQGNAEELPFE-DDSFD 113

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 489185875  127 LLLITIGVLNwMPDIARFFASVSGLLKPGGQLAIYET-HPFLEML 170
Cdd:pfam01209 114 IVTISFGLRN-FPDYLKVLKEAFRVLKPGGRVVCLEFsKPENPLL 157
PLN02244 PLN02244
tocopherol O-methyltransferase
 43-160 1.29e-04

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 42.81  E-value: 1.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  43 LDETL--AGVLRNLDLAGKAAVQVGCNNG---REVLSLYAfgvARAVGIDQSAAFLAQARQLAERS--PHQPRFVEANAY 115
Cdd:PLN02244 102 IEESLawAGVPDDDEKRPKRIVDVGCGIGgssRYLARKYG---ANVKGITLSPVQAARANALAAAQglSDKVSFQVADAL 178

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489185875 116 ELPAElNGQFDLLlitigvlnW-------MPDIARFFASVSGLLKPGGQLAI 160
Cdd:PLN02244 179 NQPFE-DGQFDLV--------WsmesgehMPDKRKFVQELARVAAPGGRIII 221
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 64-160 1.78e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 40.87  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   64 VGCNNGREVLSLYAFGvARAVGIDQSAAflaqarqLAERSPHQPRFVEANAyELPAELNGQFDLLlITIGVLNWMPDIAR 143
Cdd:pfam13489  29 FGCGTGIFLRLLRAQG-FSVTGVDPSPI-------AIERALLNVRFDQFDE-QEAAVPAGKFDVI-VAREVLEHVPDPPA 98

                          90
                  ....*....|....*..
gi 489185875  144 FFASVSGLLKPGGQLAI 160
Cdd:pfam13489  99 LLRQIAALLKPGGLLLL 115
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 41-158 5.53e-04

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 39.79  E-value: 5.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  41 SCLDETLAGVLrnLDLagkaavqvGCNNGreVLSLYA---FGVARAVGIDQSAAFLAQARQLAERspHQP---RFVEANA 114
Cdd:COG2813   43 EHLPEPLGGRV--LDL--------GCGYG--VIGLALakrNPEARVTLVDVNARAVELARANAAA--NGLenvEVLWSDG 108

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 489185875 115 YELPAElnGQFDLLL----ITIGVlNWMPDIA-RFFASVSGLLKPGGQL 158
Cdd:COG2813  109 LSGVPD--GSFDLILsnppFHAGR-AVDKEVAhALIADAARHLRPGGEL 154
Methyltransf_9 pfam08003
Protein of unknown function (DUF1698); This family contains many hypothetical proteins. It ...
 55-95 4.61e-03

Protein of unknown function (DUF1698); This family contains many hypothetical proteins. It also includes two putative methyltransferase proteins, Swiss:Q8EEE6 and Swiss:Q88MX8.


Pssm-ID: 429781 [Multi-domain]  Cd Length: 315  Bit Score: 37.77  E-value: 4.61e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 489185875   55 DLAGKAAVQVGCNNGREVLSLYAFGVARAVGIDQSAAFLAQ 95
Cdd:pfam08003 113 PLKGRTILDVGCGNGYHMWRMLGEGAAMVVGIDPSELFLCQ 153
PRK15068 PRK15068
tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB;
55-185 5.87e-03

tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB;


Pssm-ID: 237898  Cd Length: 322  Bit Score: 37.53  E-value: 5.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875  55 DLAGKAAVQVGCNNGREVLSLYAFGVARAVGIDQSAAFLAQ---ARQLAERSP---HQPRFVEanayELPAelNGQFDll 128
Cdd:PRK15068 120 PLKGRTVLDVGCGNGYHMWRMLGAGAKLVVGIDPSQLFLCQfeaVRKLLGNDQrahLLPLGIE----QLPA--LKAFD-- 191

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489185875 129 liTI---GVLNWMPDIARFFASVSGLLKPGGQLaiyethpFLEMLEPESERPFEL---------RNDYF 185
Cdd:PRK15068 192 --TVfsmGVLYHRRSPLDHLKQLKDQLVPGGEL-------VLETLVIDGDENTVLvpgdryakmRNVYF 251
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 41-160 7.66e-03

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 36.41  E-value: 7.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185875   41 SCLDETLAGVLrnLDLagkaavqvGCNNGreVLSLYA---FGVARAVGIDQSAAFLAQARQ-LAERSPHQPRFVEANAYE 116
Cdd:pfam05175  25 EHLPKDLSGKV--LDL--------GCGAG--VLGAALakeSPDAELTMVDINARALESAREnLAANGLENGEVVASDVYS 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 489185875  117 LPAElnGQFDLLL----ITIGvLNWMPDIA-RFFASVSGLLKPGGQLAI 160
Cdd:pfam05175  93 GVED--GKFDLIIsnppFHAG-LATTYNVAqRFIADAKRHLRPGGELWI 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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