N-formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilization, the hydrolysis of N-formyl-L-glutamate to produce L-glutamate plus formate; may be partial
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the ...
3-263
1.50e-147
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilization in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolysed to produce L-glutamate plus formate.
The actual alignment was detected with superfamily member TIGR02017:
Pssm-ID: 470234 Cd Length: 263 Bit Score: 413.01 E-value: 1.50e-147
N-formylglutamate amidohydrolase; In some species, histidine is converted to via urocanate and ...
3-263
1.50e-147
N-formylglutamate amidohydrolase; In some species, histidine is converted to via urocanate and then formimino-L-glutamate to glutamate in four steps, where the fourth step is conversion of N-formimino-L-glutamate to L-glutamate and formamide. In others, that pathway from formimino-L-glutamate may differ, with the next enzyme being formiminoglutamate hydrolase (HutF) yielding N-formyl-L-glutamate. This model represents the enzyme N-formylglutamate deformylase, also called N-formylglutamate amidohydrolase, which then produces glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 131072 Cd Length: 263 Bit Score: 413.01 E-value: 1.50e-147
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the ...
13-230
6.85e-94
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilization in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolysed to produce L-glutamate plus formate.
Pssm-ID: 461519 Cd Length: 219 Bit Score: 275.61 E-value: 6.85e-94
N-formylglutamate amidohydrolase; In some species, histidine is converted to via urocanate and ...
3-263
1.50e-147
N-formylglutamate amidohydrolase; In some species, histidine is converted to via urocanate and then formimino-L-glutamate to glutamate in four steps, where the fourth step is conversion of N-formimino-L-glutamate to L-glutamate and formamide. In others, that pathway from formimino-L-glutamate may differ, with the next enzyme being formiminoglutamate hydrolase (HutF) yielding N-formyl-L-glutamate. This model represents the enzyme N-formylglutamate deformylase, also called N-formylglutamate amidohydrolase, which then produces glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 131072 Cd Length: 263 Bit Score: 413.01 E-value: 1.50e-147
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the ...
13-230
6.85e-94
N-formylglutamate amidohydrolase; Formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilization in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolysed to produce L-glutamate plus formate.
Pssm-ID: 461519 Cd Length: 219 Bit Score: 275.61 E-value: 6.85e-94
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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