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Conserved domains on  [gi|489193537|ref|WP_003102870|]
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MULTISPECIES: GMC family oxidoreductase [Pseudomonas]

Protein Classification

GMC family oxidoreductase( domain architecture ID 17335521)

GMC (glucose-methanol-choline) family oxidoreductase is a flavoprotein that catalyzes the oxidation of an alcohol moiety to the corresponding aldehyde with the concomitant reduction of flavin adenine dinucleotide (FAD)

EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
78-297 1.23e-71

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


:

Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 227.55  E-value: 1.23e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537   78 YPELYQEGIGRMSKDGAITIL-QGRAVGGTTLINWTSSFRTPEPTLQHWAQVYGVKGHSAEDMAPWFEKMEQRLHVAPWA 156
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  157 LPPNANNDVIRLGCEKLGYHWKVIPRNVLGCWNLGYCGMGCPVNAKQSMLVTTIPATLDKGGELLYLARANRLLLDG--D 234
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALERNLRILTGAKAEKIIILGrgG 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489193537  235 KVTGLEClgmdeRCVAPNGRRIRVRARHYVLSGGGINTPAILLRSKAPDPSQRVGKRTFLHTV 297
Cdd:pfam00732 161 RAVGVEA-----RDGGGGIKRLITAAKEVVVAAGALNTPPLLLRSGLGKNPHPVGKNLQLHPV 218
BetA super family cl34456
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
49-531 6.97e-40

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


The actual alignment was detected with superfamily member COG2303:

Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 151.90  E-value: 6.97e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  49 LSA-AGLKVLLVEEG----------PLKTSSDFKMQEAD-AYPELYQEGIGRMSkdgaITILQGRAVGGTTLINWTSSFR 116
Cdd:COG2303   23 LSEdAGLRVLLLEAGgrdddplirmPAGYAKLLGNPRYDwRYETEPQPGLNGRR----LYWPRGKVLGGSSSINGMIYVR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 117 tPEPT-LQHWAQvYGVKGHSAEDMAPWFEKMEQR-------------LHVAPWALPpNANNDVIRLGCEKLGYhwkviPR 182
Cdd:COG2303   99 -GQPEdFDLWAQ-LGNQGWGYDDVLPYFKRAEDNergadayhgrsgpLPVSDPPLP-NPLSDAFIEAAEELGI-----PR 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 183 NV-------LGCwnlGYCGMGCPVNAKQSMLVTTIPATLDKGG-ELLYLARANRLLLDGDKVTGLECLGmdercvapNGR 254
Cdd:COG2303  171 ADdfnggacEGC---GFCQVTCRNGARWSAARAYLPPALKRPNlTVRTGALVTRILFDGGRATGVEYRD--------DGE 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 255 RIRVRA-RHYVLSGGGINTPAILLRS--KAPDPSQRVGKRTFL-----------HTVNFSAGLFDRVINpfYGAPQSIYS 320
Cdd:COG2303  240 EHTVRAaREVILAAGAINSPQLLLLSgiGPASHLREHGIPVVHdlpgvgrnlqdHLEVSVVFRFKEPVT--LNKSLRKAR 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 321 DHFQWDDGVTGRMS---------YK----LEVPPLQPSLASVLLGGFGSDNALRMEqlPHTNMMLALLRdgfhPDSaEGS 387
Cdd:COG2303  318 IGLQYLLTRSGPLTsnvaeaggfFRsdpgLERPDLQFHFLPLGLTPRWGKKALHDG--HGFTAHVEQLR----PES-RGR 390
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 388 VGLRGDD---TPVLD--YRMTDYTWDGIRRAFHTMAEIQFAAGAREVRPvhsdarsaKNLQEARGIIDGLRLEIYRTRLG 462
Cdd:COG2303  391 VTLDSADplgAPLIRpnYLSDENDRRVLVAGVRLAREIAAQPALAPYRG--------EEILPGPDVQSDEELAFIRARAY 462
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 463 SA-HVMGGCAMGEDPAvAVADSLGRHHHLRNLSIHDGSLFPTSIGANPQLSVYgltaqlasALAERLARA 531
Cdd:COG2303  463 TIyHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTI--------MLAEKAADM 523
 
Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
78-297 1.23e-71

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 227.55  E-value: 1.23e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537   78 YPELYQEGIGRMSKDGAITIL-QGRAVGGTTLINWTSSFRTPEPTLQHWAQVYGVKGHSAEDMAPWFEKMEQRLHVAPWA 156
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  157 LPPNANNDVIRLGCEKLGYHWKVIPRNVLGCWNLGYCGMGCPVNAKQSMLVTTIPATLDKGGELLYLARANRLLLDG--D 234
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALERNLRILTGAKAEKIIILGrgG 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489193537  235 KVTGLEClgmdeRCVAPNGRRIRVRARHYVLSGGGINTPAILLRSKAPDPSQRVGKRTFLHTV 297
Cdd:pfam00732 161 RAVGVEA-----RDGGGGIKRLITAAKEVVVAAGALNTPPLLLRSGLGKNPHPVGKNLQLHPV 218
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
49-531 6.97e-40

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 151.90  E-value: 6.97e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  49 LSA-AGLKVLLVEEG----------PLKTSSDFKMQEAD-AYPELYQEGIGRMSkdgaITILQGRAVGGTTLINWTSSFR 116
Cdd:COG2303   23 LSEdAGLRVLLLEAGgrdddplirmPAGYAKLLGNPRYDwRYETEPQPGLNGRR----LYWPRGKVLGGSSSINGMIYVR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 117 tPEPT-LQHWAQvYGVKGHSAEDMAPWFEKMEQR-------------LHVAPWALPpNANNDVIRLGCEKLGYhwkviPR 182
Cdd:COG2303   99 -GQPEdFDLWAQ-LGNQGWGYDDVLPYFKRAEDNergadayhgrsgpLPVSDPPLP-NPLSDAFIEAAEELGI-----PR 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 183 NV-------LGCwnlGYCGMGCPVNAKQSMLVTTIPATLDKGG-ELLYLARANRLLLDGDKVTGLECLGmdercvapNGR 254
Cdd:COG2303  171 ADdfnggacEGC---GFCQVTCRNGARWSAARAYLPPALKRPNlTVRTGALVTRILFDGGRATGVEYRD--------DGE 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 255 RIRVRA-RHYVLSGGGINTPAILLRS--KAPDPSQRVGKRTFL-----------HTVNFSAGLFDRVINpfYGAPQSIYS 320
Cdd:COG2303  240 EHTVRAaREVILAAGAINSPQLLLLSgiGPASHLREHGIPVVHdlpgvgrnlqdHLEVSVVFRFKEPVT--LNKSLRKAR 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 321 DHFQWDDGVTGRMS---------YK----LEVPPLQPSLASVLLGGFGSDNALRMEqlPHTNMMLALLRdgfhPDSaEGS 387
Cdd:COG2303  318 IGLQYLLTRSGPLTsnvaeaggfFRsdpgLERPDLQFHFLPLGLTPRWGKKALHDG--HGFTAHVEQLR----PES-RGR 390
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 388 VGLRGDD---TPVLD--YRMTDYTWDGIRRAFHTMAEIQFAAGAREVRPvhsdarsaKNLQEARGIIDGLRLEIYRTRLG 462
Cdd:COG2303  391 VTLDSADplgAPLIRpnYLSDENDRRVLVAGVRLAREIAAQPALAPYRG--------EEILPGPDVQSDEELAFIRARAY 462
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 463 SA-HVMGGCAMGEDPAvAVADSLGRHHHLRNLSIHDGSLFPTSIGANPQLSVYgltaqlasALAERLARA 531
Cdd:COG2303  463 TIyHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTI--------MLAEKAADM 523
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
384-528 1.29e-25

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 102.09  E-value: 1.29e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  384 AEGSVGLRGDD---TPVLDYRM--TDYTWDGIRRAFHTMAEIQFAAGAR---EVRPVHSDARSAKNLQEArgiiDGLRLE 455
Cdd:pfam05199   3 SRGRVTLSSSDptgLPVIDPNYlsDPADLAALRAALRLARRILAAAGLVlgvELTPGPVPEVSDAAVTSD----DELLAY 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489193537  456 IYRTRLGSAHVMGGCAMGEDPAVAVADSLGRHHHLRNLSIHDGSLFPTSIGANPQLSVYgltaqlasALAERL 528
Cdd:pfam05199  79 IRAAASTSYHPMGTCRMGADPDDAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIY--------ALAERA 143
PRK02106 PRK02106
choline dehydrogenase; Validated
224-508 9.33e-09

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 57.92  E-value: 9.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 224 ARANRLLLDGDKVTGLEclgmdercVAPNGRRIRVRARHYV-LSGGGINTPAILLRSKapdpsqrVGKRTFLHtvnfSAG 302
Cdd:PRK02106 222 ALTDRILFEGKRAVGVE--------YERGGGRETARARREViLSAGAINSPQLLQLSG-------IGPAEHLK----ELG 282
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 303 lfdrvINPFYGAP------QsiysDHFQwddgVTgrMSYKLEVP-PLQPSL---------ASVLLG--GFGSDNALRM-- 362
Cdd:PRK02106 283 -----IPVVHDLPgvgenlQ----DHLE----VY--IQYECKQPvSLYPALkwwnkpkigAEWLFTgtGLGASNHFEAgg 347
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 363 -----EQLPHTNMMLALL-------------RDGF--H-----PDSaEGSVGLRGDD---TPVLD--YRMTDYTWDGIRR 412
Cdd:PRK02106 348 firsrAGVDWPNIQYHFLpvairydgsnavkGHGFqaHvgpmrSPS-RGSVKLKSADpraHPSILfnYMSTEQDWREFRD 426
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 413 AFHTMAEIqFAAGA------REVRP---VHSDARsaknlqeargiIDglrlEIYRTRLGSA-HVMGGCAMGEDPaVAVAD 482
Cdd:PRK02106 427 AIRLTREI-MAQPAldpyrgREISPgadVQTDEE-----------ID----AFVREHAETAyHPSCTCKMGTDP-MAVVD 489
                        330       340
                 ....*....|....*....|....*.
gi 489193537 483 SLGRHHHLRNLSIHDGSLFPTSIGAN 508
Cdd:PRK02106 490 PEGRVHGVEGLRVVDASIMPTITNGN 515
 
Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
78-297 1.23e-71

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 227.55  E-value: 1.23e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537   78 YPELYQEGIGRMSKDGAITIL-QGRAVGGTTLINWTSSFRTPEPTLQHWAQVYGVKGHSAEDMAPWFEKMEQRLHVAPWA 156
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  157 LPPNANNDVIRLGCEKLGYHWKVIPRNVLGCWNLGYCGMGCPVNAKQSMLVTTIPATLDKGGELLYLARANRLLLDG--D 234
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALERNLRILTGAKAEKIIILGrgG 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489193537  235 KVTGLEClgmdeRCVAPNGRRIRVRARHYVLSGGGINTPAILLRSKAPDPSQRVGKRTFLHTV 297
Cdd:pfam00732 161 RAVGVEA-----RDGGGGIKRLITAAKEVVVAAGALNTPPLLLRSGLGKNPHPVGKNLQLHPV 218
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
49-531 6.97e-40

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 151.90  E-value: 6.97e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  49 LSA-AGLKVLLVEEG----------PLKTSSDFKMQEAD-AYPELYQEGIGRMSkdgaITILQGRAVGGTTLINWTSSFR 116
Cdd:COG2303   23 LSEdAGLRVLLLEAGgrdddplirmPAGYAKLLGNPRYDwRYETEPQPGLNGRR----LYWPRGKVLGGSSSINGMIYVR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 117 tPEPT-LQHWAQvYGVKGHSAEDMAPWFEKMEQR-------------LHVAPWALPpNANNDVIRLGCEKLGYhwkviPR 182
Cdd:COG2303   99 -GQPEdFDLWAQ-LGNQGWGYDDVLPYFKRAEDNergadayhgrsgpLPVSDPPLP-NPLSDAFIEAAEELGI-----PR 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 183 NV-------LGCwnlGYCGMGCPVNAKQSMLVTTIPATLDKGG-ELLYLARANRLLLDGDKVTGLECLGmdercvapNGR 254
Cdd:COG2303  171 ADdfnggacEGC---GFCQVTCRNGARWSAARAYLPPALKRPNlTVRTGALVTRILFDGGRATGVEYRD--------DGE 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 255 RIRVRA-RHYVLSGGGINTPAILLRS--KAPDPSQRVGKRTFL-----------HTVNFSAGLFDRVINpfYGAPQSIYS 320
Cdd:COG2303  240 EHTVRAaREVILAAGAINSPQLLLLSgiGPASHLREHGIPVVHdlpgvgrnlqdHLEVSVVFRFKEPVT--LNKSLRKAR 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 321 DHFQWDDGVTGRMS---------YK----LEVPPLQPSLASVLLGGFGSDNALRMEqlPHTNMMLALLRdgfhPDSaEGS 387
Cdd:COG2303  318 IGLQYLLTRSGPLTsnvaeaggfFRsdpgLERPDLQFHFLPLGLTPRWGKKALHDG--HGFTAHVEQLR----PES-RGR 390
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 388 VGLRGDD---TPVLD--YRMTDYTWDGIRRAFHTMAEIQFAAGAREVRPvhsdarsaKNLQEARGIIDGLRLEIYRTRLG 462
Cdd:COG2303  391 VTLDSADplgAPLIRpnYLSDENDRRVLVAGVRLAREIAAQPALAPYRG--------EEILPGPDVQSDEELAFIRARAY 462
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 463 SA-HVMGGCAMGEDPAvAVADSLGRHHHLRNLSIHDGSLFPTSIGANPQLSVYgltaqlasALAERLARA 531
Cdd:COG2303  463 TIyHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTI--------MLAEKAADM 523
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
384-528 1.29e-25

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 102.09  E-value: 1.29e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537  384 AEGSVGLRGDD---TPVLDYRM--TDYTWDGIRRAFHTMAEIQFAAGAR---EVRPVHSDARSAKNLQEArgiiDGLRLE 455
Cdd:pfam05199   3 SRGRVTLSSSDptgLPVIDPNYlsDPADLAALRAALRLARRILAAAGLVlgvELTPGPVPEVSDAAVTSD----DELLAY 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489193537  456 IYRTRLGSAHVMGGCAMGEDPAVAVADSLGRHHHLRNLSIHDGSLFPTSIGANPQLSVYgltaqlasALAERL 528
Cdd:pfam05199  79 IRAAASTSYHPMGTCRMGADPDDAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIY--------ALAERA 143
PRK02106 PRK02106
choline dehydrogenase; Validated
224-508 9.33e-09

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 57.92  E-value: 9.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 224 ARANRLLLDGDKVTGLEclgmdercVAPNGRRIRVRARHYV-LSGGGINTPAILLRSKapdpsqrVGKRTFLHtvnfSAG 302
Cdd:PRK02106 222 ALTDRILFEGKRAVGVE--------YERGGGRETARARREViLSAGAINSPQLLQLSG-------IGPAEHLK----ELG 282
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 303 lfdrvINPFYGAP------QsiysDHFQwddgVTgrMSYKLEVP-PLQPSL---------ASVLLG--GFGSDNALRM-- 362
Cdd:PRK02106 283 -----IPVVHDLPgvgenlQ----DHLE----VY--IQYECKQPvSLYPALkwwnkpkigAEWLFTgtGLGASNHFEAgg 347
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 363 -----EQLPHTNMMLALL-------------RDGF--H-----PDSaEGSVGLRGDD---TPVLD--YRMTDYTWDGIRR 412
Cdd:PRK02106 348 firsrAGVDWPNIQYHFLpvairydgsnavkGHGFqaHvgpmrSPS-RGSVKLKSADpraHPSILfnYMSTEQDWREFRD 426
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489193537 413 AFHTMAEIqFAAGA------REVRP---VHSDARsaknlqeargiIDglrlEIYRTRLGSA-HVMGGCAMGEDPaVAVAD 482
Cdd:PRK02106 427 AIRLTREI-MAQPAldpyrgREISPgadVQTDEE-----------ID----AFVREHAETAyHPSCTCKMGTDP-MAVVD 489
                        330       340
                 ....*....|....*....|....*.
gi 489193537 483 SLGRHHHLRNLSIHDGSLFPTSIGAN 508
Cdd:PRK02106 490 PEGRVHGVEGLRVVDASIMPTITNGN 515
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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