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Conserved domains on  [gi|489200309|ref|WP_003109534|]
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MULTISPECIES: AraC family transcriptional regulator [Pseudomonas]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 12168323)

AraC family transcriptional regulator containing a cupin domain as its effector domain and an AraC family helix-turn-helix (HTH) DNA binding domain, controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  2.60.120.10
Gene Ontology:  GO:0003700|GO:0006355|GO:0043565
PubMed:  11282467|33837749|9409145|12270809|19478949|14697267|9573603
SCOP:  3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraC_binding_2 pfam14525
AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.
 25-195 2.47e-20

AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.


:

Pssm-ID: 434015  Cd Length: 173  Bit Score: 86.21  E-value: 2.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   25 VNRHVGTHCIRLPAAGRPQASLDHRTFASLDLCRISYGAAVRVTSPALESIFHLQILLRGHCLWRGGGQEHALAPGELLL 104
Cdd:pfam14525   5 VSRAFGPHRLRPLGPDRFDARLRGVRLGGLSLGRLRYGAAVHIRPPELDDFYLLQLPLSGSAEIEQGGREVVLGPGDAVL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  105 INPDDPVDLTYSADCEKFIVKLPC-ALLEaicaeqrwsHPARGVRFLEHRYRLDQLEG--FVGLLALVCREAESGERL-- 179
Cdd:pfam14525  85 LDPGRPYRLRWSEDCEQLVLRIPLrALLG---------RPLRRPLRFAPRLDLDSGLGalWLRLLRLLAAELAALGPAla 155

                         170
                  ....*....|....*...
gi 489200309  180 --ARVDSHFEQILGSKLL 195
Cdd:pfam14525 156 ssPLVAAQLEELLASLLL 173
HTH_18 pfam12833
Helix-turn-helix domain;
234-316 2.90e-14

Helix-turn-helix domain;


:

Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 66.84  E-value: 2.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  234 LAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACL-EDPGCRVrnlTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSV---AEIALALGFSDASHFSRAFRRLFGLTPSE 77


                  ....
gi 489200309  313 TLRR 316
Cdd:pfam12833  78 YRRR 81
 
Name Accession Description Interval E-value
AraC_binding_2 pfam14525
AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.
 25-195 2.47e-20

AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.


Pssm-ID: 434015  Cd Length: 173  Bit Score: 86.21  E-value: 2.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   25 VNRHVGTHCIRLPAAGRPQASLDHRTFASLDLCRISYGAAVRVTSPALESIFHLQILLRGHCLWRGGGQEHALAPGELLL 104
Cdd:pfam14525   5 VSRAFGPHRLRPLGPDRFDARLRGVRLGGLSLGRLRYGAAVHIRPPELDDFYLLQLPLSGSAEIEQGGREVVLGPGDAVL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  105 INPDDPVDLTYSADCEKFIVKLPC-ALLEaicaeqrwsHPARGVRFLEHRYRLDQLEG--FVGLLALVCREAESGERL-- 179
Cdd:pfam14525  85 LDPGRPYRLRWSEDCEQLVLRIPLrALLG---------RPLRRPLRFAPRLDLDSGLGalWLRLLRLLAAELAALGPAla 155

                         170
                  ....*....|....*...
gi 489200309  180 --ARVDSHFEQILGSKLL 195
Cdd:pfam14525 156 ssPLVAAQLEELLASLLL 173
HTH_18 pfam12833
Helix-turn-helix domain;
234-316 2.90e-14

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 66.84  E-value: 2.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  234 LAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACL-EDPGCRVrnlTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSV---AEIALALGFSDASHFSRAFRRLFGLTPSE 77


                  ....
gi 489200309  313 TLRR 316
Cdd:pfam12833  78 YRRR 81
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
228-314 1.22e-12

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 62.57  E-value: 1.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   228 EIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGcrvRNLTELALDFGFAHLGRFAEQYRRQFG 307
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTD---LSVTEIALRVGFSSQSYFSRAFKKLFG 77


                   ....*..
gi 489200309   308 ELPSETL 314
Cdd:smart00342  78 VTPSEYR 84
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 76-318 7.20e-11

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 61.97  E-value: 7.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  76 FHLQILLRGHCLWRGGGQEHALAPGELLLINPDDPVDLTYSADCEKFIVKLPCALLEAICaeqrwshPARGVRFLEhryR 155
Cdd:PRK09685  72 FFTVFQLSGHAIIEQDDRQVQLAAGDITLIDASRPCSIYPQGLSEQISLLLPRELVEQYF-------PGQKPACAG---R 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 156 LDQLEGFVGLLALVCREAESGERLARVDShfeQILGSKLLTLLKTNVSR--EDPGDAQVVFARLDAYIRRHLQSE-IEVA 232
Cdd:PRK09685 142 LSASLPMVQLSHRLLQQSMNGPALSETES---EALLEALIALLRPALHQreSVQPRRERQFQKVVALIDQSIQEEiLRPE 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 233 ALAEQAHMSTRSLYALFERQlGESPRQYIRRLRLERIRACLeDPGCRVRNLTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:PRK09685 219 WIAGELGISVRSLYRLFAEQ-GLVVAQYIRNRRLDRCADDL-RPAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGE 296


                 ....*.
gi 489200309 313 tLRRRA 318
Cdd:PRK09685 297 -YRRKF 301
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 204-317 1.50e-10

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 60.94  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 204 REDPGDAQVvfARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGcrvRNL 283
Cdd:COG4977  204 PLGHRDPRL--ARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTD---LSI 278

                         90       100       110
                 ....*....|....*....|....*....|....
gi 489200309 284 TELALDFGFAHLGRFAEQYRRQFGELPSEtLRRR 317
Cdd:COG4977  279 EEIAAACGFGSASHFRRAFRRRFGVSPSA-YRRR 311
ftrA PRK09393
transcriptional activator FtrA; Provisional
 214-317 3.60e-05

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 44.95  E-value: 3.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 214 FARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGCRVRNLTELAldfGFA 293
Cdd:PRK09393 220 LGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERA---GFG 296

                         90       100
                 ....*....|....*....|....
gi 489200309 294 HLGRFAEQYRRQFGELPSeTLRRR 317
Cdd:PRK09393 297 SEESLRHHFRRRAATSPA-AYRKR 319
 
Name Accession Description Interval E-value
AraC_binding_2 pfam14525
AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.
 25-195 2.47e-20

AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.


Pssm-ID: 434015  Cd Length: 173  Bit Score: 86.21  E-value: 2.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   25 VNRHVGTHCIRLPAAGRPQASLDHRTFASLDLCRISYGAAVRVTSPALESIFHLQILLRGHCLWRGGGQEHALAPGELLL 104
Cdd:pfam14525   5 VSRAFGPHRLRPLGPDRFDARLRGVRLGGLSLGRLRYGAAVHIRPPELDDFYLLQLPLSGSAEIEQGGREVVLGPGDAVL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  105 INPDDPVDLTYSADCEKFIVKLPC-ALLEaicaeqrwsHPARGVRFLEHRYRLDQLEG--FVGLLALVCREAESGERL-- 179
Cdd:pfam14525  85 LDPGRPYRLRWSEDCEQLVLRIPLrALLG---------RPLRRPLRFAPRLDLDSGLGalWLRLLRLLAAELAALGPAla 155

                         170
                  ....*....|....*...
gi 489200309  180 --ARVDSHFEQILGSKLL 195
Cdd:pfam14525 156 ssPLVAAQLEELLASLLL 173
HTH_18 pfam12833
Helix-turn-helix domain;
234-316 2.90e-14

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 66.84  E-value: 2.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  234 LAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACL-EDPGCRVrnlTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSV---AEIALALGFSDASHFSRAFRRLFGLTPSE 77


                  ....
gi 489200309  313 TLRR 316
Cdd:pfam12833  78 YRRR 81
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
228-314 1.22e-12

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 62.57  E-value: 1.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   228 EIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGcrvRNLTELALDFGFAHLGRFAEQYRRQFG 307
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTD---LSVTEIALRVGFSSQSYFSRAFKKLFG 77


                   ....*..
gi 489200309   308 ELPSETL 314
Cdd:smart00342  78 VTPSEYR 84
AraC_binding pfam02311
AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization ...
 54-190 1.94e-12

AraC-like ligand binding domain; This family represents the arabinose-binding and dimerization domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with the helix-turn-helix (HTH) DNA-binding motif pfam00165. This domain is distantly related to the Cupin domain pfam00190.


Pssm-ID: 396749 [Multi-domain]  Cd Length: 134  Bit Score: 63.61  E-value: 1.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309   54 LDLCRISYGAAVRVTSPALESIFHLQILLRGHCLWRGGGQEHALAPGELLLINPDDPVDLTYSAD--CEKFIVKLPCALL 131
Cdd:pfam02311   2 PGLEGIEARYPGHSFPPHVHDFYVIGYIERGVGRFRLNGRTYHLGPGDLFLLPPGEPHDYEPESEdgWRYRWLYFEPELL 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489200309  132 EAICAEQRWSHPARGVrFLEHRYRLDQLEGFVGLLAlvcrEAESGERLARvDSHFEQIL 190
Cdd:pfam02311  82 ERILADISILAGGPLP-LLRDPELAALLRALFRLLE----EAGRSDDLLA-EALLYQLL 134
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 76-318 7.20e-11

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 61.97  E-value: 7.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309  76 FHLQILLRGHCLWRGGGQEHALAPGELLLINPDDPVDLTYSADCEKFIVKLPCALLEAICaeqrwshPARGVRFLEhryR 155
Cdd:PRK09685  72 FFTVFQLSGHAIIEQDDRQVQLAAGDITLIDASRPCSIYPQGLSEQISLLLPRELVEQYF-------PGQKPACAG---R 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 156 LDQLEGFVGLLALVCREAESGERLARVDShfeQILGSKLLTLLKTNVSR--EDPGDAQVVFARLDAYIRRHLQSE-IEVA 232
Cdd:PRK09685 142 LSASLPMVQLSHRLLQQSMNGPALSETES---EALLEALIALLRPALHQreSVQPRRERQFQKVVALIDQSIQEEiLRPE 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 233 ALAEQAHMSTRSLYALFERQlGESPRQYIRRLRLERIRACLeDPGCRVRNLTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:PRK09685 219 WIAGELGISVRSLYRLFAEQ-GLVVAQYIRNRRLDRCADDL-RPAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGE 296


                 ....*.
gi 489200309 313 tLRRRA 318
Cdd:PRK09685 297 -YRRKF 301
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 204-317 1.50e-10

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 60.94  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 204 REDPGDAQVvfARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGcrvRNL 283
Cdd:COG4977  204 PLGHRDPRL--ARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTD---LSI 278

                         90       100       110
                 ....*....|....*....|....*....|....
gi 489200309 284 TELALDFGFAHLGRFAEQYRRQFGELPSEtLRRR 317
Cdd:COG4977  279 EEIAAACGFGSASHFRRAFRRRFGVSPSA-YRRR 311
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
215-318 7.43e-10

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 58.64  E-value: 7.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 215 ARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGcrvRNLTELALDFGFAH 294
Cdd:COG2207  155 LLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETD---LSISEIAYELGFSS 231

                         90       100
                 ....*....|....*....|....
gi 489200309 295 LGRFAEQYRRQFGELPSETLRRRA 318
Cdd:COG2207  232 QSHFSRAFKKRFGVTPSEYRKRLR 255
PRK10130 PRK10130
HTH-type transcriptional regulator EutR;
142-317 5.21e-09

HTH-type transcriptional regulator EutR;


Pssm-ID: 182258 [Multi-domain]  Cd Length: 350  Bit Score: 56.85  E-value: 5.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 142 HPARGVRFLEHRYRLDQLEGFVGLLALVCREA-----ESGERLARvdSHFEQILGSKLLTLLKTNVSREDPGDA------ 210
Cdd:PRK10130 158 NPERVLHMLRNQSALEVKEQHKAALWGFVQQAlatfcENPENLHQ--PAVRKVLGDNLLMAMGAMLEEAQPMVTaesish 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 211 ---QVVFARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGCRVRNLTELA 287
Cdd:PRK10130 236 qsyRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNAFHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAA 315

                        170       180       190
                 ....*....|....*....|....*....|
gi 489200309 288 LDFGFAHLGRFAEQYRRQFGELPSETLRRR 317
Cdd:PRK10130 316 MQWGFWHLGQFATDYQQLFAEKPSLTLHQR 345
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 221-260 7.09e-07

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 45.22  E-value: 7.09e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 489200309  221 IRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQY 260
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQY 40
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 207-318 1.77e-06

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 48.90  E-value: 1.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 207 PGDAQVVfARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPgcrvRNLTEL 286
Cdd:COG2169   80 PPRADLV-ARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLLQTG----LSVTDA 154

                         90       100       110
                 ....*....|....*....|....*....|..
gi 489200309 287 ALDFGFAHLGRFAEQYRRQFGELPSEtLRRRA 318
Cdd:COG2169  155 AYAAGFGSLSRFYEAFKKLLGMTPSA-YRRGG 185
ftrA PRK09393
transcriptional activator FtrA; Provisional
 214-317 3.60e-05

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 44.95  E-value: 3.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 214 FARLDAYIRRHLQSEIEVAALAEQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGCRVRNLTELAldfGFA 293
Cdd:PRK09393 220 LGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERA---GFG 296

                         90       100
                 ....*....|....*....|....
gi 489200309 294 HLGRFAEQYRRQFGELPSeTLRRR 317
Cdd:PRK09393 297 SEESLRHHFRRRAATSPA-AYRKR 319
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
156-312 5.84e-03

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 37.73  E-value: 5.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489200309 156 LDQLEGFVGLLALVcREAESGERLARVDSHFEQilgskLLTLLKTNVSREDPGDAQVVFARLDAYIRRHLQSEIEVAALA 235
Cdd:PRK13503 121 LQQVRQLVAQMEQQ-EESNDLEAIASREILFMQ-----LLVLLRKSSLQENGENSDARLNQLLAWLEDHFAEEVNWEALA 194

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489200309 236 EQAHMSTRSLYALFERQLGESPRQYIRRLRLERIRACLEDPGCRVrnlTELALDFGFAHLGRFAEQYRRQFGELPSE 312
Cdd:PRK13503 195 DQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASV---TDIAYRCGFGDSNHFSTLFRREFSWSPRD 268
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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