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Conserved domains on  [gi|489205076|ref|WP_003114132|]
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alpha/beta hydrolase PoxA [Pseudomonas aeruginosa]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
13-288 7.71e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 96.61  E-value: 7.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGKPLLhFLHGNGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESDHGGRFHGWNRNAEMAVEAFEA-GRG 91
Cdd:COG0596   11 GVRLHYREAGPDGPPVV-LLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDAlGLE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  92 PYgdvqrLACGHSFGGVLSSLVLARHPTLFARAVLLDPVlftpamigvmalsetlglqlrgsLAKKARLRRSQWPDRAAA 171
Cdd:COG0596   90 RV-----VLVGHSMGGMVALELAARHPERVAGLVLVDEV-----------------------LAALAEPLRRPGLAPEAL 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 172 YAGLRgrgifkgwtdealwayveyALKESDggvelkcrpsreaeifssfprrLWPSLGKITTPTRVLYGDRTYPFVAKSV 251
Cdd:COG0596  142 AALLR-------------------ALARTD----------------------LRERLARITVPTLVIWGEKDPIVPPALA 180
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489205076 252 ARWCSLNPQVSAHVVVG-GHCFMQEDPADAAERVRDFL 288
Cdd:COG0596  181 RRLAELLPNAELVVLPGaGHFPPLEQPEAFAAALRDFL 218
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
13-288 7.71e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 96.61  E-value: 7.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGKPLLhFLHGNGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESDHGGRFHGWNRNAEMAVEAFEA-GRG 91
Cdd:COG0596   11 GVRLHYREAGPDGPPVV-LLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDAlGLE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  92 PYgdvqrLACGHSFGGVLSSLVLARHPTLFARAVLLDPVlftpamigvmalsetlglqlrgsLAKKARLRRSQWPDRAAA 171
Cdd:COG0596   90 RV-----VLVGHSMGGMVALELAARHPERVAGLVLVDEV-----------------------LAALAEPLRRPGLAPEAL 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 172 YAGLRgrgifkgwtdealwayveyALKESDggvelkcrpsreaeifssfprrLWPSLGKITTPTRVLYGDRTYPFVAKSV 251
Cdd:COG0596  142 AALLR-------------------ALARTD----------------------LRERLARITVPTLVIWGEKDPIVPPALA 180
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489205076 252 ARWCSLNPQVSAHVVVG-GHCFMQEDPADAAERVRDFL 288
Cdd:COG0596  181 RRLAELLPNAELVVLPGaGHFPPLEQPEAFAAALRDFL 218
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
26-242 2.52e-12

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 64.93  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076   26 KPLLHFLHG-NGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESD-HGGRFHGWNRNAEMAVEAFEAGRGPYGDVQRLACGH 103
Cdd:pfam12146   4 RAVVVLVHGlGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDgKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLGH 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  104 SFGGVLSSLVLARHPTLFARAVLLDPVLFTPAMIGVMALseTLGLQLRGSLAKKARLR-------RSQWPDRAAAYAG-- 174
Cdd:pfam12146  84 SMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPIL--KLLAKLLGKLFPRLRVPnnllpdsLSRDPEVVAAYAAdp 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489205076  175 LRGRGIFKGWTDEALwayveyalkesDGGvelkcrpsreaeifssfpRRLWPSLGKITTPTRVLYGDR 242
Cdd:pfam12146 162 LVHGGISARTLYELL-----------DAG------------------ERLLRRAAAITVPLLLLHGGA 200
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
13-288 7.00e-03

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 37.62  E-value: 7.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGKPLLHFLHGNGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESDH---GGRFhgwnrnAEMA--VEAFE 87
Cdd:PRK14875 118 GRTVRYLRLGEGDGTPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGASSKavgAGSL------DELAaaVLAFL 191
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  88 AGRGpygdVQR--LAcGHSFGGVLSSLVLARHPTLFARAVLLDPVLFTPAMIG------VMALS-ETLGLQLRGSLAKKA 158
Cdd:PRK14875 192 DALG----IERahLV-GHSMGGAVALRLAARAPQRVASLTLIAPAGLGPEINGdyidgfVAAESrRELKPVLELLFADPA 266
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 159 RLRRsQWPDRAAAYAGLRGRgifkgwtDEALWAYVEYALkesdggvelkcRPSREAEIFSsfprrlwPSLGKITTPTRVL 238
Cdd:PRK14875 267 LVTR-QMVEDLLKYKRLDGV-------DDALRALADALF-----------AGGRQRVDLR-------DRLASLAIPVLVI 320
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489205076 239 YG--DRTYPFvakSVARwcSLNPQVSAHVVVG-GHCFMQEDPADAAERVRDFL 288
Cdd:PRK14875 321 WGeqDRIIPA---AHAQ--GLPDGVAVHVLPGaGHMPQMEAAADVNRLLAEFL 368
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
13-288 7.71e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 96.61  E-value: 7.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGKPLLhFLHGNGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESDHGGRFHGWNRNAEMAVEAFEA-GRG 91
Cdd:COG0596   11 GVRLHYREAGPDGPPVV-LLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDAlGLE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  92 PYgdvqrLACGHSFGGVLSSLVLARHPTLFARAVLLDPVlftpamigvmalsetlglqlrgsLAKKARLRRSQWPDRAAA 171
Cdd:COG0596   90 RV-----VLVGHSMGGMVALELAARHPERVAGLVLVDEV-----------------------LAALAEPLRRPGLAPEAL 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 172 YAGLRgrgifkgwtdealwayveyALKESDggvelkcrpsreaeifssfprrLWPSLGKITTPTRVLYGDRTYPFVAKSV 251
Cdd:COG0596  142 AALLR-------------------ALARTD----------------------LRERLARITVPTLVIWGEKDPIVPPALA 180
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489205076 252 ARWCSLNPQVSAHVVVG-GHCFMQEDPADAAERVRDFL 288
Cdd:COG0596  181 RRLAELLPNAELVVLPGaGHFPPLEQPEAFAAALRDFL 218
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
1-129 2.98e-16

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 75.81  E-value: 2.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076   1 MSLSPWFHSCSAGFTLRGWRSEPSG--KPLLHFLHGNGFCGRTYEPMLRLLAE-DFDLWLCDIQGHGESD-HGGRFHGWN 76
Cdd:COG2267    1 MTRRLVTLPTRDGLRLRGRRWRPAGspRGTVVLVHGLGEHSGRYAELAEALAAaGYAVLAFDLRGHGRSDgPRGHVDSFD 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489205076  77 RNAEMAVEAFEAGRGPYGDvQRLACGHSFGGVLSSLVLARHPTLFARAVLLDP 129
Cdd:COG2267   81 DYVDDLRAALDALRARPGL-PVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP 132
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
26-242 2.52e-12

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 64.93  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076   26 KPLLHFLHG-NGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESD-HGGRFHGWNRNAEMAVEAFEAGRGPYGDVQRLACGH 103
Cdd:pfam12146   4 RAVVVLVHGlGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDgKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLGH 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  104 SFGGVLSSLVLARHPTLFARAVLLDPVLFTPAMIGVMALseTLGLQLRGSLAKKARLR-------RSQWPDRAAAYAG-- 174
Cdd:pfam12146  84 SMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPIL--KLLAKLLGKLFPRLRVPnnllpdsLSRDPEVVAAYAAdp 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489205076  175 LRGRGIFKGWTDEALwayveyalkesDGGvelkcrpsreaeifssfpRRLWPSLGKITTPTRVLYGDR 242
Cdd:pfam12146 162 LVHGGISARTLYELL-----------DAG------------------ERLLRRAAAITVPLLLLHGGA 200
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
27-277 6.70e-11

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 60.98  E-value: 6.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076   27 PLLHFLHGNGFCGRTYEPMLRLLAED-FDLWLCDIQGHGESDHGGRFHGWNrnAEMAVEAFEAGRGPYGDVQRLACGHSF 105
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDgFRVIALDLRGFGKSSRPKAQDDYR--TDDLAEDLEYILEALGLEKVNLVGHSM 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  106 GGVLSSLVLARHPTLFARAVLLDPVLFTPAMI-GVMALSETLGLQLRGSLAKKARLRRSQWPDRAAAYAGLRGRGIFK-- 182
Cdd:pfam00561  79 GGLIALAYAAKYPDRVKALVLLGALDPPHELDeADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKAlp 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  183 GWTDEALWAYVEYALKESDGGVELKCRPSREAEiFSSFPRRLWPSLgkittptrVLYGDRTYPFVAKSVARWCSLNPQVS 262
Cdd:pfam00561 159 LLNKRFPSGDYALAKSLVTGALLFIETWSTELR-AKFLGRLDEPTL--------IIWGDQDPLVPPQALEKLAQLFPNAR 229
                         250
                  ....*....|....*.
gi 489205076  263 AHVVV-GGHCFMQEDP 277
Cdd:pfam00561 230 LVVIPdAGHFAFLEGP 245
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
13-130 1.87e-08

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 53.87  E-value: 1.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGK---PLLHFLHGNGF-CGRTYEPMLRLLAED-FDLWLCDIQGHGESDhGGRFHGWNRNAEMAVEAFE 87
Cdd:COG1506    7 GTTLPGWLYLPADGkkyPVVVYVHGGPGsRDDSFLPLAQALASRgYAVLAPDYRGYGESA-GDWGGDEVDDVLAAIDYLA 85
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 489205076  88 AGrgPYGDVQRLAC-GHSFGGVLSSLVLARHPTLFARAVLLDPV 130
Cdd:COG1506   86 AR--PYVDPDRIGIyGHSYGGYMALLAAARHPDRFKAAVALAGV 127
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
31-283 1.57e-06

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 47.85  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076   31 FLHGNGFcgrTYEPMLRLLAEDFDLWLCDIQGHGESDHggRFHGWNRNAEmaVEAFEAGRGPYGDVqrLACGHSFGGVLS 110
Cdd:pfam12697   3 LVHGAGL---SAAPLAALLAAGVAVLAPDLPGHGSSSP--PPLDLADLAD--LAALLDELGAARPV--VLVGHSLGGAVA 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  111 SLVLARhptLFARAVLLDPVLFTPAMIgvmalsetlglqlrgslakkarlrrsqwPDRAAAYAGLRGRGIFKGWTDEAlw 190
Cdd:pfam12697  74 LAAAAA---ALVVGVLVAPLAAPPGLL----------------------------AALLALLARLGAALAAPAWLAAE-- 120
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  191 AYVEYALKESDGGVELKCRPSREAEIFSSFPRRLWPSLGKITTPTRVLYGDRtyPFVAKSVARWCSLNPQVSAHVVVG-G 269
Cdd:pfam12697 121 SLARGFLDDLPADAEWAAALARLAALLAALALLPLAAWRDLPVPVLVLAEED--RLVPELAQRLLAALAGARLVVLPGaG 198
                         250
                  ....*....|....
gi 489205076  270 HCFMqEDPADAAER 283
Cdd:pfam12697 199 HLPL-DDPEEVAEA 211
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
28-288 4.86e-06

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 46.86  E-value: 4.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  28 LLHflhgnGFCGRTYEpmLRLLAE-----DFDLWLCDIQGHGESDHGGRFHGWNRNAEMAVEAFEAGRGPYGDVqrLACG 102
Cdd:COG1647   20 LLH-----GFTGSPAE--MRPLAEalakaGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGYDKV--IVIG 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 103 HSFGGVLSSLVLARHPTLfARAVLLDPVLFtpaMIGVMALSETLGLQLRGSLAKKArlRRSQWPDRA-AAYAGLRGRGIf 181
Cdd:COG1647   91 LSMGGLLALLLAARYPDV-AGLVLLSPALK---IDDPSAPLLPLLKYLARSLRGIG--SDIEDPEVAeYAYDRTPLRAL- 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 182 kgwtdEALWAYVEYALKEsdggvelkcrpsreaeifssfprrlwpsLGKITTPTRVLYG--DRTYPF--VAKSVARWCSL 257
Cdd:COG1647  164 -----AELQRLIREVRRD----------------------------LPKITAPTLIIQSrkDEVVPPesARYIYERLGSP 210
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 489205076 258 NPQV-----SAHVVVGGHcfmqeDPADAAERVRDFL 288
Cdd:COG1647  211 DKELvwledSGHVITLDK-----DREEVAEEILDFL 241
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
60-130 2.51e-04

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 41.45  E-value: 2.51e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489205076   60 IQGHGESDHGGRFH--GWNRNAEMAVEAFEAGR-----GPYGDVQRLAC-GHSFGGVLSSLVLARHPTLFARAVLLDPV 130
Cdd:pfam00326  20 ANGRGSGGYGEAFHdaGKGDLGQNEFDDFIAAAeylieQGYTDPDRLAIwGGSYGGYLTGAALNQRPDLFKAAVAHVPV 98
COG4757 COG4757
Predicted alpha/beta hydrolase [General function prediction only];
10-126 8.30e-04

Predicted alpha/beta hydrolase [General function prediction only];


Pssm-ID: 443790 [Multi-domain]  Cd Length: 289  Bit Score: 40.25  E-value: 8.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  10 CSAGFTLRG--WRSEPSGKPLLHFLHGNGFCGRTYEPMLRLLAE-DFDLWLCDIQGHGESDHG-GRFHGWnRNAEMAVEA 85
Cdd:COG4757   14 AADGYPLAArlFPPAGPPRAVVLINPATGVPQRFYRPFARYLAErGFAVLTYDYRGIGLSRPGsLRGFDA-GYRDWGELD 92
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 489205076  86 FEAG----RGPYGDVQRLACGHSFGGVLssLVLARHPTLFARAVL 126
Cdd:COG4757   93 LPAVldalRARFPGLPLLLVGHSLGGQL--LGLAPNAERVDRLVT 135
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
13-135 6.49e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 37.25  E-value: 6.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGK---PLLHFLHGNGFCGRTYEPMLRLLAED------FDLWlcDIQGHGESDHGGRFHGWNRNAEMAV 83
Cdd:COG0412   13 GVTLPGYLARPAGGgprPGVVVLHEIFGLNPHIRDVARRLAAAgyvvlaPDLY--GRGGPGDDPDEARALMGALDPELLA 90
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489205076  84 EAFEAGRG-----PYGDVQRLAC-GHSFGGVLsSLVLARHPTLFARAVLLDPVLFTPA 135
Cdd:COG0412   91 ADLRAALDwlkaqPEVDAGRVGVvGFCFGGGL-ALLAAARGPDLAAAVSFYGGLPADD 147
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
97-129 6.83e-03

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 37.27  E-value: 6.83e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 489205076  97 QRLACGHSFGGVLSSLVLARHPTLFARAVLLDP 129
Cdd:COG2819  131 RTGLIGHSLGGLFSLYALLKYPDLFGRYIAISP 163
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
13-288 7.00e-03

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 37.62  E-value: 7.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  13 GFTLRGWRSEPSGKPLLHFLHGNGFCGRTYEPMLRLLAEDFDLWLCDIQGHGESDH---GGRFhgwnrnAEMA--VEAFE 87
Cdd:PRK14875 118 GRTVRYLRLGEGDGTPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGASSKavgAGSL------DELAaaVLAFL 191
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076  88 AGRGpygdVQR--LAcGHSFGGVLSSLVLARHPTLFARAVLLDPVLFTPAMIG------VMALS-ETLGLQLRGSLAKKA 158
Cdd:PRK14875 192 DALG----IERahLV-GHSMGGAVALRLAARAPQRVASLTLIAPAGLGPEINGdyidgfVAAESrRELKPVLELLFADPA 266
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489205076 159 RLRRsQWPDRAAAYAGLRGRgifkgwtDEALWAYVEYALkesdggvelkcRPSREAEIFSsfprrlwPSLGKITTPTRVL 238
Cdd:PRK14875 267 LVTR-QMVEDLLKYKRLDGV-------DDALRALADALF-----------AGGRQRVDLR-------DRLASLAIPVLVI 320
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489205076 239 YG--DRTYPFvakSVARwcSLNPQVSAHVVVG-GHCFMQEDPADAAERVRDFL 288
Cdd:PRK14875 321 WGeqDRIIPA---AHAQ--GLPDGVAVHVLPGaGHMPQMEAAADVNRLLAEFL 368
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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