|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
1-382 |
0e+00 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 762.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 1 MIQSKLPNVGTTIFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGR 80
Cdd:PRK09082 7 IPQSKLPNVGTTIFTVMSALAAEHGAINLSQGFPDFDGPPYLVEALAYAMAAGHNQYPPMTGVAALREAIAAKTARLYGR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 81 RVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRL 160
Cdd:PRK09082 87 QYDADSEITVTAGATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQPPDFRVDWQRFAAAISPRTRL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 161 VIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTG 240
Cdd:PRK09082 167 IILNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRERAFVVSSFGKTYHVTGWKVG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 241 YVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDY 320
Cdd:PRK09082 247 YCVAPAALSAEFRKVHQYNTFTVNTPAQLALADYLRAEPEHYLELPAFYQAKRDRFRAALANSRFKLLPCEGTYFQLVDY 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489210460 321 SAIrPDLDDVAMAEWLTREHGVAAIPVSVFYEKAPDaMRLVRFCYAKREETLRQAAEKLCAI 382
Cdd:PRK09082 327 SAI-SDLDDVEFCQWLTREHGVAAIPLSVFYADPFP-HRLVRLCFAKQEETLDAAAERLCQL 386
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
2-381 |
3.02e-156 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 444.96 E-value: 3.02e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 2 IQSKLPNVGTTIFTRMSQLAAEC-----GAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQ 76
Cdd:COG0436 3 LSSRLARLPPSPIREVSALAAELkaageDVIDLGIGEPDFPTPDHIREAAIEALDDGVTGYTPSAGIPELREAIAAYYKR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 77 FYGRRVSADsEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVL-PDFSIDWQRMAEAIG 155
Cdd:COG0436 83 RYGVDLDPD-EILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEeNGFLPDPEALEAAIT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 156 PRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVT 235
Cdd:COG0436 162 PRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGLKDRTIVINSFSKSYAMT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 236 GWKTGYVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYF 315
Cdd:COG0436 242 GWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAALEGPQDYVEEMRAEYRRRRDLLVEGLNEIGLSVVKPEGAFY 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489210460 316 QCVDYSAIRpdLDDVAMAEWLTREHGVAAIPVSVFYEKAPDamrLVRFCYAKREETLRQAAEKLCA 381
Cdd:COG0436 322 LFADVPELG--LDSEEFAERLLEEAGVAVVPGSAFGPAGEG---YVRISYATSEERLEEALERLAR 382
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
3-382 |
3.27e-155 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 442.30 E-value: 3.27e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 3 QSKLPNVGTTIFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRV 82
Cdd:PRK12414 8 RSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHNQYAPMAGIAALREALAEKTERLYGARY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 83 SADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRLVI 162
Cdd:PRK12414 88 DPASEVTVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEDFRVNWDEVAAAITPRTRMII 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 163 INTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYV 242
Cdd:PRK12414 168 VNTPHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAERSVIVSSFGKSYHVTGWRVGYC 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 243 VAPPALSAELRKVHQYVNFCGVTPLQWALADYMAgHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSA 322
Cdd:PRK12414 248 LAPAELMDEIRKVHQFMVFSADTPMQHAFAEALA-EPASYLGLGAFYQRKRDLLARELAGSRFELLPSEGSFFMLARFRH 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 323 IRpDLDDVAMAEWLTREHGVAAIPVSVFYEKAPDAmRLVRFCYAKREETLRQAAEKLCAI 382
Cdd:PRK12414 327 FS-DESDSDFVLRLIRDARVATIPLSAFYTDGTDT-GLIRLSFSKDDATLVEGARRLCSL 384
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
1-379 |
6.66e-142 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 408.59 E-value: 6.66e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 1 MIQSKLPNVGTTIFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGR 80
Cdd:PRK08912 3 MGNPVFADLPTTIFEVMSQLAREHGAINLGQGFPDDPGPEDVRRAAADALLDGSNQYPPMMGLPELRQAVAAHYARFQGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 81 RVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRL 160
Cdd:PRK08912 83 DLDPETEVMVTSGATEALAAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLVRLEPPHWRLPRAALAAAFSPRTKA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 161 VIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTG 240
Cdd:PRK08912 163 VLLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMRERTVKIGSAGKIFSLTGWKVG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 241 YVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDY 320
Cdd:PRK08912 243 FVCAAPPLLRVLAKAHQFLTFTTPPNLQAAVAYGLGKPDDYFEGMRADLARSRDRLAAGLRRIGFPVLPSQGTYFLTVDL 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 489210460 321 SAIRPDLDDVAMAEWLTREHGVAAIPVSVFYEKAPdAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK08912 323 APLGLAEDDVAFCRRLVEEAGVAAIPVSAFYEEDP-VTSVVRFCFAKRDATLDEAVERL 380
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
1-382 |
7.34e-142 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 408.27 E-value: 7.34e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 1 MIQSKLPNVGTTIFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGR 80
Cdd:PRK07777 1 MTVSRLRPFGTTIFAEMSALAVRTGAVNLGQGFPDEDGPPEMLEAAQEAIAGGVNQYPPGPGIPELRAAIAAQRRRRYGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 81 RVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRT 158
Cdd:PRK07777 81 EYDPDTEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVPDGrgFALDLDALRAAVTPRT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 159 RLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWK 238
Cdd:PRK07777 161 RALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLPGMRERTVTISSAAKTFNVTGWK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 239 TGYVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCV 318
Cdd:PRK07777 241 IGWACGPAPLIAAVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSLQAKRDRLAAGLAEAGFEVHDSAGTYFLCA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489210460 319 DYSAIRPDlDDVAMAEWLTREHGVAAIPVSVFYEKAPDAMRLVRFCYAKREETLRQAAEKLCAI 382
Cdd:PRK07777 321 DPRPLGYD-DGTEFCRALPERVGVAAIPMSVFYDPADAWNHLVRFAFCKRDDTLDEAIRRLRAL 383
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
2-379 |
3.49e-120 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 354.17 E-value: 3.49e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 2 IQSKLPNVGTTIFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRR 81
Cdd:PLN00175 32 VAKRLEKFKTTIFTQMSSLAIKHGAINLGQGFPNFDGPDFVKEAAIQAIRDGKNQYARGFGVPELNSAIAERFKKDTGLV 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 82 VSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRLV 161
Cdd:PLN00175 112 VDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTLRPPDFAVPEDELKAAFTSKTRAI 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 162 IINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGY 241
Cdd:PLN00175 192 LINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEG-DHISMASLPGMYERTVTMNSLGKTFSLTGWKIGW 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 242 VVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYS 321
Cdd:PLN00175 271 AIAPPHLTWGVRQAHSFLTFATATPMQWAAVAALRAPESYYEELKRDYSAKKDILVEGLKEVGFKVYPSSGTYFVMVDHT 350
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 489210460 322 AIRPDlDDVAMAEWLTREHGVAAIPVSVFYEKAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PLN00175 351 PFGFE-NDIAFCEYLIEEVGVAAIPPSVFYLNPEDGKNLVRFAFCKDEETLRAAVERM 407
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
27-379 |
2.32e-101 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 303.88 E-value: 2.32e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREA-VGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQAL 105
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEAlAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPE-EIVVTNGAQEALSLLLRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 106 VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD-FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAA 184
Cdd:cd00609 80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGgFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LIRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPP-ALSAELRKVHQYVNFCG 263
Cdd:cd00609 160 LAKKHGILIISDEAYAELVYDG-EPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPeELLERLKKLLPYTTSGP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 264 VTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRF-RFTRAPGTYFQCVDYsairPDLDDVAMAEWLTREHGV 342
Cdd:cd00609 239 STLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPlVVVKPSGGFFLWLDL----PEGDDEEFLERLLLEAGV 314
|
330 340 350
....*....|....*....|....*....|....*..
gi 489210460 343 AAIPVSVFYEKAPDAmrlVRFCYAKREETLRQAAEKL 379
Cdd:cd00609 315 VVRPGSAFGEGGEGF---VRLSFATPEEELEEALERL 348
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
17-379 |
5.82e-89 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 273.54 E-value: 5.82e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 17 MSQLAAECGA-----INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTIT 91
Cdd:PRK05764 19 VTAKAKELKAqgrdvISLGAGEPDFDTPEHIKEAAIEALDDGKTKYTPAAGIPELREAIAAKLKRDNGLDYDPS-QVIVT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 92 PGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLvLPD--FSIDWQRMAEAIGPRTRLVIINTPHNP 169
Cdd:PRK05764 98 TGAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPT-GEEngFKLTVEQLEAAITPKTKALILNSPSNP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 170 SGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLS-HDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPAL 248
Cdd:PRK05764 177 TGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASlSPELRDRTITVNGFSKAYAMTGWRLGYAAGPKEL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 249 SAELRKVHQYVNFCGVTPLQW----ALADYMAgHPEHLRQLpgfYQAKRDLFCDLLldsrfrfTRAPGtyFQC------- 317
Cdd:PRK05764 257 IKAMSKLQSHSTSNPTSIAQYaavaALNGPQD-EVEEMRQA---FEERRDLMVDGL-------NEIPG--LECpkpegaf 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489210460 318 ---VDYSAI--RPDLDDVAMAEWLTREHGVAAIPVSVFyekapDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK05764 324 yvfPNVSKLlgKSITDSLEFAEALLEEAGVAVVPGIAF-----GAPGYVRLSYATSLEDLEEGLERI 385
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
27-379 |
1.06e-68 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 220.25 E-value: 1.06e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAG-HNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQAL 105
Cdd:pfam00155 4 INLGSNEYLGDTLPAVAKAEKDALAGGtRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVVFGSGAGANIEALIFLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 106 VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAA 184
Cdd:pfam00155 84 ANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSnDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVATLEELEKLLD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCgv 264
Cdd:pfam00155 164 LAKEHNILLLVDEAYAGFVFGSPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARPFYSS-- 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 265 TPLQWALADYMAG---HPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSAirpdLDDVAMAEWLTREHG 341
Cdd:pfam00155 242 THLQAAAAAALSDpllVASELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGFFLLTGLDP----ETAKELAQVLLEEVG 317
|
330 340 350
....*....|....*....|....*....|....*....
gi 489210460 342 VAAIPVSVFYEKApdamrLVRFCYAKR-EETLRQAAEKL 379
Cdd:pfam00155 318 VYVTPGSSPGVPG-----WLRITVAGGtEEELEELLEAI 351
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
1-379 |
3.09e-67 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 217.67 E-value: 3.09e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 1 MIQSKLPNVGTTIFTRMSQLAA-ECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYG 79
Cdd:PRK07683 4 LINPRVKDIQISGIRQFSNMVQnYDNLISLTIGQPDFPTPSHVKEAAKRAITENYTSYTHNAGLLELRKAACNFVKDKYD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 80 RRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTR 159
Cdd:PRK07683 84 LHYSPESEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTRSTGFRLTAEALENAITEKTR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 160 LVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKT 239
Cdd:PRK07683 164 CVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHFPEMREKTIVINGLSKSHSMTGWRI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 240 GYVVAPPALSAELRKVHQYVNFCGVTPLQW-ALADYMAG--HPEHLRQLpgfYQAKRDLFCDLLLDSRFRFTRAPGTYFQ 316
Cdd:PRK07683 243 GFLFAPSYLAKHILKVHQYNVTCASSISQYaALEALTAGkdDAKMMRHQ---YKKRRDYVYNRLISMGLDVEKPTGAFYL 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489210460 317 CVDYSAIRPDLDDVAMAewLTREHGVAAIPVSVFYEKAPDAMRLvrfCYAKREETLRQAAEKL 379
Cdd:PRK07683 320 FPSIGHFTMSSFDFALD--LVEEAGLAVVPGSAFSEYGEGYVRL---SYAYSIETLKEGLDRL 377
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
25-379 |
1.03e-62 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 205.35 E-value: 1.03e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQA 104
Cdd:PRK07682 21 GVISLGVGEPDFVTPWNVREASIRSLEQGYTSYTANAGLLELRQEIAKYLKKRFAVSYDPNDEIIVTVGASQALDVAMRA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 105 LVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLA 183
Cdd:PRK07682 101 IINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLEnEFKVQPAQIEAAITAKTKAILLCSPNNPTGAVLNKSELEEIA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 184 ALIRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCG 263
Cdd:PRK07682 181 VIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILISGFSKGFAMTGWRLGFIAAPVYFSEAMLKIHQYSMMCA 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 264 VTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRfTRAPGTYFQCvdYSAIRPD-LDDVAMAEWLTREHGV 342
Cdd:PRK07682 260 PTMAQFAALEALRAGNDDVIRMRDSYRKRRNFFVTSFNEIGLT-CHVPGGAFYA--FPSISSTgLSSEEFAEQLLLEEKV 336
|
330 340 350
....*....|....*....|....*....|....*..
gi 489210460 343 AAIPVSVFyekAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07682 337 AVVPGSVF---GESGEGFIRCSYATSLEQLQEAMKRM 370
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
25-379 |
5.54e-62 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 203.80 E-value: 5.54e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQA 104
Cdd:PRK07309 31 GILKLTLGEPDFTTPDHVKEAAKRAIDANQSHYTGMAGLLELRQAAADFVKEKYNLDYAPENEILVTIGATEALSASLTA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 105 LVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAI---GPRTRLVIINTPHNPSGALISREELDR 181
Cdd:PRK07309 111 ILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDFVLTPEMLEKAIleqGDKLKAVILNYPANPTGVTYSREQIKA 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 182 LAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHdeLYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNF 261
Cdd:PRK07309 191 LADVLKKYDIFVISDEVYSELTYTGEPHVSIAEY--LPDQTILINGLSKSHAMTGWRIGLIFAPAEFTAQLIKSHQYLVT 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 262 CGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQcvdYSAIrPD---LDDVAMAEWLTR 338
Cdd:PRK07309 269 AATTMAQFAAVEALTNGKDDALPMKKEYIKRRDYIIEKMTDLGFKIIKPDGAFYI---FAKI-PAgynQDSFKFLQDFAR 344
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 489210460 339 EHGVAAIPVSVFyekAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07309 345 KKAVAFIPGAAF---GPYGEGYVRLSYAASMETIKEAMKRL 382
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
13-377 |
4.23e-61 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 201.57 E-value: 4.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 13 IFTRMSQLAAECGAINL---SQGFPDFDGPPELREAVgRHIAAGHNQ----YAPMTGLPALREQVAKKIEQFYGRRVSAD 85
Cdd:PRK06836 19 MFEEGARLKAEYGADNVfdfSLGNPSVPPPAAVKEAL-RELAEEEDPglhgYMPNAGYPEVREAIAESLNRRFGTPLTAD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 86 sEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRLVIINT 165
Cdd:PRK06836 98 -HIVMTCGAAGALNVALKAILNPGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTDTDTFQPDLDALEAAITPKTKAVIINS 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 166 PHNPSGALISREELDRLAALIRD------RDIYLISDEVYEHLVFDGVAHTSVLShdeLYPRSFVVSSFGKTYHVTGWKT 239
Cdd:PRK06836 177 PNNPTGVVYSEETLKALAALLEEkskeygRPIYLISDEPYREIVYDGAEVPYIFK---YYDNSIVVYSFSKSLSLPGERI 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 240 GYVVAPPALsAELRKVHQYVNFCG-----VTP---LQWALADyMAGHPEHLrqlpGFYQAKRDLFCDLLLDSRFRFTRAP 311
Cdd:PRK06836 254 GYIAVNPEM-EDADDLVAALVFANrilgfVNApalMQRVVAK-CLDATVDV----SIYKRNRDLLYDGLTELGFECVKPQ 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489210460 312 GTYF---QCvdysairPDLDDVAMAEwLTREHGVAAIPVSVFyeKAPDAMRLVrFCYAkrEETLRQAAE 377
Cdd:PRK06836 328 GAFYlfpKS-------PEEDDVAFCE-KAKKHNLLLVPGSGF--GCPGYFRLS-YCVD--TETIERSLP 383
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
13-379 |
2.51e-60 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 199.72 E-value: 2.51e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 13 IFTRMSQLAaecGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSeVTITP 92
Cdd:PRK08361 25 LFERASKME---NVISLGIGEPDFDTPKNIKEAAKRALDEGWTHYTPNAGIPELREAIAEYYKKFYGVDVDVDN-VIVTA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 93 GATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DFSIDWQRMAEAIGPRTRLVIINTPHNPSG 171
Cdd:PRK08361 101 GAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREEnEFQPDPDELLELITKRTRMIVINYPNNPTG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 172 ALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDElyPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAE 251
Cdd:PRK08361 181 ATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYAP--DNTILANSFSKTFAMTGWRLGFVIAPEQVIKD 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 252 LRKVHQY--------VNFCGVTPLQ----WALAdymaghpEHLRQLpgfYQAKRDLFCDLLLD-SRFRFTRAPGTYFqcv 318
Cdd:PRK08361 259 MIKLHAYiignvasfVQIAGIEALRskesWKAV-------EEMRKE---YNERRKLVLKRLKEmPHIKVFEPKGAFY--- 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489210460 319 dysaIRPDLDDVAM-----AEWLTREHGVAAIPVSVFyekAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK08361 326 ----VFANIDETGMssedfAEWLLEKARVVVIPGTAF---GKAGEGYIRISYATSKEKLIEAMERM 384
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
34-380 |
3.64e-58 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 193.62 E-value: 3.64e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 34 PDFdgppeLREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGDEVV 113
Cdd:PRK06108 39 PDF-----IRDAAAAALADGETFYTHNLGIPELREALARYVSRLHGVATPPE-RIAVTSSGVQALMLAAQALVGPGDEVV 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 114 VLDPSYDSYEPSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDI 191
Cdd:PRK06108 113 AVTPLWPNLVAAPKILGARVVCVPLDFGGggWTLDLDRLLAAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGL 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 192 YLISDEVYEHLVFD-GVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCGVTPLQWA 270
Cdd:PRK06108 193 WIVADEVYERLYYApGGRAPSFLDIAEPDDRIIFVNSFSKNWAMTGWRLGWLVAPPALGQVLEKLIEYNTSCVAQFVQRA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 271 LADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDS-RFRFTRAPGTYfqcvdYSAIRPD--LDDVAMAEWLTREHGVAAIPV 347
Cdd:PRK06108 273 AVAALDEGEDFVAELVARLRRSRDHLVDALRALpGVEVAKPDGAM-----YAFFRIPgvTDSLALAKRLVDEAGLGLAPG 347
|
330 340 350
....*....|....*....|....*....|...
gi 489210460 348 SVFyekAPDAMRLVRFCYAKREETLRQAAEKLC 380
Cdd:PRK06108 348 TAF---GPGGEGFLRWCFARDPARLDEAVERLR 377
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
25-379 |
9.08e-56 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 187.59 E-value: 9.08e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFPDFDGPPELREAVGRHIAAGHN-QYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQ 103
Cdd:PRK05957 28 GTISLGQGVVSYPPPPEAIEALNNFLANPENhKYQAVQGIPPLLEAITQKLQQDNGIELNNEQAIVVTAGSNMAFMNAIL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 104 ALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPlVLPDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLA 183
Cdd:PRK05957 108 AITDPGDEIILNTPYYFNHEMAITMAGCQPILVP-TDDNYQLQPEAIEQAITPKTRAIVTISPNNPTGVVYPEALLRAVN 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 184 ALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCG 263
Cdd:PRK05957 187 QICAEHGIYHISDEAYEYFTYDGVKHFSPGSIPGSGNHTISLYSLSKAYGFASWRIGYMVIPIHLLEAIKKIQDTILICP 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 264 VTPLQW-ALADYMAGhPEHLRQ-LPGFYQaKRDLFCDLLLDS-RFRFTRAPGTYFQCvdYSAIRPDLDDVAMAEWLTREH 340
Cdd:PRK05957 267 PVVSQYaALGALQVG-KSYCQQhLPEIAQ-VRQILLKSLGQLqDRCTLHPANGAFYC--FLKVNTDLNDFELVKQLIREY 342
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 489210460 341 GVAAIPVSVFYEKAPDAMRLVrfcY-AKREETLRQAAEKL 379
Cdd:PRK05957 343 RVAVIPGTTFGMKNGCYLRIA---YgALQKATAKEGIERL 379
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
27-379 |
1.15e-54 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 185.32 E-value: 1.15e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVsADSEVTITPGATEAIFSAIQALV 106
Cdd:PRK06107 36 VDLTVGEPDFDTPDHIKQAAVAAIERGETKYTLVNGTPALRKAIIAKLERRNGLHY-ADNEITVGGGAKQAIFLALMATL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 107 HPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD-FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAA- 184
Cdd:PRK06107 115 EAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPEEQgFKLTPEALEAAITPRTRWLILNAPSNPTGAVYSRAELRALADv 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LIRDRDIYLISDEVYEHLVFDGVAHTSVLS-HDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCG 263
Cdd:PRK06107 195 LLRHPHVLVLTDDIYDHIRFDDEPTPHLLAaAPELRDRVLVTNGVSKTYAMTGWRIGYAAGPADLIAAINKLQSQSSSCP 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 264 VTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLldsrfrfTRAPG-----------TYFQCV--------DYSAIR 324
Cdd:PRK06107 275 SSISQAAAAAALNGDQSFVTESVAVYKQRRDYALALL-------NAIPGlsclvpdgafyLYVNCAgligkttpEGKVLE 347
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 489210460 325 PDLDDVAmaeWLTREHGVAAIPVSVfYEKAPdamrLVRFCYAKREETLRQAAEKL 379
Cdd:PRK06107 348 TDQDVVL---YLLDSAGVAVVQGTA-YGLSP----YFRLSIATSLETLEEACARI 394
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
25-382 |
4.64e-53 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 182.72 E-value: 4.64e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFPDFDGPP--ELREAVGRHIAAGHNQ---YAPMTGLPALREQVAkkieQFYGRR---VSADsEVTITPGATE 96
Cdd:COG1167 107 GVIDLGSGAPDPDLFPlaALRRALRRALRRLPPAllgYGDPQGLPELREAIA----RYLARRgvpASPD-QILITSGAQQ 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 97 AIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPL----VLPDfsidwqRMAEAIG-PRTRLVIInTP--HNP 169
Cdd:COG1167 182 ALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVdedgLDLD------ALEAALRrHRPRAVYV-TPshQNP 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 170 SGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDElYPRSFVVSSFGKTyHVTGWKTGYVVAPPALS 249
Cdd:COG1167 255 TGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDA-PGRVIYIGSFSKT-LAPGLRLGYLVAPGRLI 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 250 AELRKVHQYVNFCGVTPLQWALADYMA-GH-PEHLRQLPGFYQAKRDLFCDLL---LDSRFRFTRAPGTYFQCVDysaIR 324
Cdd:COG1167 333 ERLARLKRATDLGTSPLTQLALAEFLEsGHyDRHLRRLRREYRARRDLLLAALarhLPDGLRVTGPPGGLHLWLE---LP 409
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489210460 325 PDLDDVAMAEWLtREHGVAAIPVSVFY--EKAPDAMRLvrfCYAK-REETLRQAAEKLCAI 382
Cdd:COG1167 410 EGVDAEALAAAA-LARGILVAPGSAFSadGPPRNGLRL---GFGApSEEELEEALRRLAEL 466
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
27-379 |
1.18e-52 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 179.48 E-value: 1.18e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAkkieQFYGRRVSAD---SEVTITPGATEAIFSAIQ 103
Cdd:PRK08960 35 IHLEIGEPDFTTAEPIVAAGQAALAAGHTRYTAARGLPALREAIA----GFYAQRYGVDvdpERILVTPGGSGALLLASS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 104 ALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPlVLPDfsIDWQRMAEAI----GPRTRLVIINTPHNPSGALISREEL 179
Cdd:PRK08960 111 LLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVP-VGPD--SRYQLTPALVerhwNADTVGALVASPANPTGTLLSRDEL 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 180 DRLAALIRDRDIYLISDEVYEHLVFdGVAHTSVLSHDElypRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYV 259
Cdd:PRK08960 188 AALSQALRARGGHLVVDEIYHGLTY-GVDAASVLEVDD---DAFVLNSFSKYFGMTGWRLGWLVAPPAAVPELEKLAQNL 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 260 NFCGVTPLQW-ALAdymAGHPEHLRQLP---GFYQAKRDLFCDLLLDSRFRFTRAP-GTYFQCVDYSAIrpDLDDVAMAE 334
Cdd:PRK08960 264 YISASTPAQHaALA---CFEPETLAILEarrAEFARRRDFLLPALRELGFGIAVEPqGAFYLYADISAF--GGDAFAFCR 338
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 489210460 335 WLTREHGVAAIPVSVFYEKAPDamRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK08960 339 HFLETEHVAFTPGLDFGRHQAG--QHVRFAYTQSLPRLQEAVERI 381
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
27-379 |
1.03e-51 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 177.17 E-value: 1.03e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSAdSEVTITPGATEAIFSAIQALV 106
Cdd:PRK07337 33 IHMGIGEPDFTAPEPVVEAAARALRRGVTQYTSALGLAPLREAIAAWYARRFGLDVAP-ERIVVTAGASAALLLACLALV 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 107 HPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD-FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAAL 185
Cdd:PRK07337 112 ERGDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPAErFQLTAADVEAAWGERTRGVLLASPSNPTGTSIAPDELRRIVEA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 186 IRDRDIYLISDEVYEHLVFDGVAHtSVLSHDElypRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCGVT 265
Cdd:PRK07337 192 VRARGGFTIVDEIYQGLSYDAAPV-SALSLGD---DVITINSFSKYFNMTGWRLGWLVVPEALVGTFEKLAQNLFICASA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 266 PLQWA---------LADYmaghpEHLRQLpgfYQAKRDLFCDLLLDSRFRFTRAP-GTYFQCVDYSAI-RPDL-DDVAMA 333
Cdd:PRK07337 268 LAQHAalacfepdtLAIY-----ERRRAE---FKRRRDFIVPALESLGFKVPVMPdGAFYVYADCRGVaHPAAgDSAALT 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489210460 334 EWLTREHGVAAIPVSVFYEKAPDamRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07337 340 QAMLHDAGVVLVPGRDFGPHAPR--DYIRLSYATSMSRLEEAVARL 383
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
35-360 |
8.47e-47 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 164.11 E-value: 8.47e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 35 DFDGPPELREAVGRHIAAGHNQYAPMTglPALREQVAKKIEQFYGRRVSADSeVTITPGATEAIFSAIQALVHPGDEVVV 114
Cdd:COG1168 40 DFATPPAVIEALKERVEHGVFGYTAPP--DEYYEAIIDWLKRRHGWEIDPEW-IVFTPGVVPGLALAIRAFTEPGDGVLI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 115 LDPSYDSYEPSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIY 192
Cdd:COG1168 117 QTPVYPPFFKAIENNGRELVENPLILEDgrYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVL 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 193 LISDEVyeH--LVFDGVAHTSVLS-HDELYPRSFVVSSFGKTYHVTGWKTGYVVAP-PALSAELRKVHQYVNFCGVTPL- 267
Cdd:COG1168 197 VISDEI--HadLVLPGHKHTPFASlSEEAADRTITLTSPSKTFNLAGLKASYAIIPnPALRARFARALEGLGLPSPNVLg 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 268 QWAL-ADYMAGHpEHLRQLPGFYQAKRDLFCDlLLDSRF---RFTRAPGTYFQCVDYSAIrpDLDDVAMAEWLTREHGVA 343
Cdd:COG1168 275 LVATeAAYREGE-EWLDELLAYLRGNRDLLAE-FLAEHLpgvKVTPPEATYLAWLDCRAL--GLDDEELAEFLLEKAGVA 350
|
330
....*....|....*..
gi 489210460 344 AIPVSVFYEKAPDAMRL 360
Cdd:COG1168 351 LSDGATFGEGGEGFVRL 367
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
27-295 |
4.10e-46 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 162.67 E-value: 4.10e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFP---DFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQ 103
Cdd:PRK08363 33 IRLNIGDPvkfDFQPPEHMKEAYCRAIKEGHNYYGPSEGLPELREAIVKREKRKNGVDITPD-DVRVTAAVTEALQLIFG 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 104 ALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDfsiDWQ----RMAEAIGPRTRLVIINTPHNPSGALISREEL 179
Cdd:PRK08363 112 ALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEYRTIEEE---GWQpdidDIRKKITEKTKAIAVINPNNPTGALYEKKTL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 180 DRLAALIRDRDIYLISDEVYEHLVFDG--VAHTSVLSHDELyprsFVVSSFGKTYHVTGWKTGYV--VAPPALSAELRKV 255
Cdd:PRK08363 189 KEILDIAGEHDLPVISDEIYDLMTYEGkhVSPGSLTKDVPV----IVMNGLSKVYFATGWRLGYIyfVDPEGKLAEVREA 264
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 489210460 256 ---HQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDL 295
Cdd:PRK08363 265 idkLARIRLCPNTPAQFAAIAGLTGPMDYLEEYMKKLKERRDY 307
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
27-379 |
4.78e-46 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 162.05 E-value: 4.78e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQ-YAPMTGLPALREQVAKKIEQFYGRRVSAdSEVTITPGATEAIFSAIQAL 105
Cdd:PRK07550 32 IDLSQAVPGYPPPPELLRALAEAAADPAAHlYGPVEGLPELREAYAAHYSRLYGAAISP-EQVHITSGCNQAFWAAMVTL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 106 VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVL-PDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAA 184
Cdd:PRK07550 111 AGAGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEgPGLLPDPAAAEALITPRTRAIALVTPNNPTGVVYPPELLHELYD 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LIRDRDIYLISDEVYEHLVFDGVAHTSVLShDELYPRSFV-VSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFC- 262
Cdd:PRK07550 191 LARRHGIALILDETYRDFDSGGGAPHDLFA-DPDWDDTLVhLYSFSKSYALTGHRVGAVVASPARIAEIEKFMDTVAICa 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 263 ---GVTPLQWA---LADYMAGhpEHLRQLpgfyqAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSAirPDLDDVAMAEWL 336
Cdd:PRK07550 270 priGQIAVAWGlpnLADWRAG--NRAEIA-----RRRDAFRAVFARLPGWELLASGAYFAYVRHPF--PDRPSREVARRL 340
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 489210460 337 TREHGVAAIPVSVFyekAPDAMRLVRFCYAK-REETLRQAAEKL 379
Cdd:PRK07550 341 AKEAGILCLPGTMF---GPGQEGYLRLAFANaDVAGIGELVERL 381
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
27-270 |
1.69e-45 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 160.66 E-value: 1.69e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSAdSEVTITPGATEAIFSAIQALV 106
Cdd:PRK06348 32 IDLSLGDPDLITDESIINAAFEDAKKGHTRYTDSGGDVELIEEIIKYYSKNYDLSFKR-NEIMATVGACHGMYLALQSIL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 107 HPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD-FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAAL 185
Cdd:PRK06348 111 DPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDgFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKI 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 186 IRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFCGVT 265
Cdd:PRK06348 191 AIEYDLFIISDEVYDGFSFYE-DFVPMATLAGMPERTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEGICFSAPT 269
|
....*
gi 489210460 266 PLQWA 270
Cdd:PRK06348 270 ISQRA 274
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
39-257 |
1.13e-42 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 151.82 E-value: 1.13e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 39 PPELREAVGRHIAAGhNQYaPMTGLPALREQVAkkieQFYGrrVSADsEVTITPGATEAIFSAIQALVHPGDEVVVLDPS 118
Cdd:COG0079 28 PPKVLEAIAAALDAL-NRY-PDPDATALREALA----EYYG--VPPE-QVLVGNGSDELIQLLARAFLGPGDEVLVPEPT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 119 YDSYEPSVQLAGGRCVHVPLvLPDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIrDRDIYLISDEV 198
Cdd:COG0079 99 FSEYPIAARAAGAEVVEVPL-DEDFSLDLDALLAAITERTDLVFLCNPNNPTGTLLPREELEALLEAL-PADGLVVVDEA 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 489210460 199 YEHLVfdgVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQ 257
Cdd:COG0079 177 YAEFV---PEEDSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRG 232
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
35-379 |
7.18e-39 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 142.84 E-value: 7.18e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 35 DFDGPPELREAVGR---HIAAGHNQYAPmtglpALREQVAKKIEQFYGRRVSADSEVtITPGATEAIFSAIQALVHPGDE 111
Cdd:TIGR04350 36 DFATPPAVLEALKQrleHPVFGYTLPPD-----SLYAAVINWLAQRHGWQIDPEDIV-FLPGVVPSLFAAVRALTAPGEG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 112 VVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDR 189
Cdd:TIGR04350 110 VIVQTPVYPPFLSAVKSNGRELVLNPLKLDEgrYRFDLEDLEDAITEKARLLLLCSPHNPVGRVWTREELTRLAELCLRH 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 190 DIYLISDEVYEHLVFDGVAHTSVLS-HDELYPRSFVVSSFGKTYHVTGWKTGYVVAP-PALSAELRKVHQYVNFCGVTPL 267
Cdd:TIGR04350 190 NVVVVSDEIHADLVYPPNKHIPLASlSPEPAERTVTLLSPGKTFNIAGLNISFAIIPnPELRRAFQEAAQRVHIQHGNLF 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 268 QWA--LADYMAGHPeHLRQLPGFYQAKRDLFCDLL--LDSRFRFTRAPGTYFQCVDYSAIrpDLDDVAMAEWLTREHGVA 343
Cdd:TIGR04350 270 GYVafEAAYRDGEP-WLDALLAYLRGNRDLVEEFIakRLPQIRVRPPEATYLAWLDCRAL--GLDDADLRAFFIEQAGLG 346
|
330 340 350
....*....|....*....|....*....|....*.
gi 489210460 344 AIPVSVFYEKAPDAMRLvrfCYAKREETLRQAAEKL 379
Cdd:TIGR04350 347 LNPGISFGDGGSGFMRL---NFGCPRSTLEQALERL 379
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
5-382 |
9.09e-36 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 134.93 E-value: 9.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 5 KLPNVGTTIFTRMSQLAAECGA-----INLSQGFPDFDGPPELREAVGrHIAAGHNQYA-PMTGLPALREQVAKKIEQFY 78
Cdd:PRK07681 8 RMKAFQSSIFSELGAYKKEKIAaghkmIDLSIGNPDMPPADFVREEMV-HTANQKESYGyTLSGIQEFHEAVTEYYNNTH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 79 GRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DFSIDWQRMAEAIGPR 157
Cdd:PRK07681 87 NVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKEnDFLPDLELIPEEIADK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 158 TRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGW 237
Cdd:PRK07681 167 AKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKSYSLAGS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 238 KTGYVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQc 317
Cdd:PRK07681 247 RIGYMIGNEEIVRALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWNVDKPAGSMFV- 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489210460 318 vdYSAIRPDLDDVAMAEWLTREHGVAAIPVSVFyekAPDAMRLVRFCYAKREETLRQAAEKLCAI 382
Cdd:PRK07681 326 --WAEIPKGWTSLSFAYALMDRANVVVTPGHAF---GPHGEGFVRIALVQDEEVLQQAVENIRNS 385
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
32-379 |
2.05e-35 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 133.82 E-value: 2.05e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 32 GFPDFDGPPELREAVgRHIAAGHNQYAPMTGLPALREQVAKKIEQfYGRRVSADsEVTITPGATEAIFSAIQALVHPGDE 111
Cdd:PRK07568 38 GQPDIKTPEVFFEAI-KNYDEEVLAYSHSQGIPELREAFAKYYKK-WGIDVEPD-EILITNGGSEAILFAMMAICDPGDE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 112 VVVLDPSYDSYEPSVQLAGGRCVHVPLVLPD-FSI-DWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDR 189
Cdd:PRK07568 115 ILVPEPFYANYNGFATSAGVKIVPVTTKIEEgFHLpSKEEIEKLITPKTKAILISNPGNPTGVVYTKEELEMLAEIAKKH 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 190 DIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAP-PALSAELRKVHQyVNFCGVTPLQ 268
Cdd:PRK07568 195 DLFLISDEVYREFVYDGLKYTSALSLEGLEDRVIIIDSVSKRYSACGARIGCLISKnKELIAAAMKLCQ-ARLSPPTLEQ 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 269 WALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVdysAIRP--DLDDVAMaeWLTRE---HG-- 341
Cdd:PRK07568 274 IGAAALLDTPESYFDEVREEYKKRRDILYEELNKIPGVVCEKPKGAFYII---AKLPvdDAEDFAK--WLLTDfnyNGet 348
|
330 340 350
....*....|....*....|....*....|....*...
gi 489210460 342 VAAIPVSVFYEKAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07568 349 VMVAPASGFYATPGLGKNEIRIAYVLNEEDLKRAMEIL 386
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
14-300 |
1.90e-33 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 128.11 E-value: 1.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 14 FTRMSQLAAECGA-----INLSQGFPDFDGPP----ELREAVgrHIAAGHnQYAPMTGLPALREQVAKKIEQFYGRRVSA 84
Cdd:PRK09276 16 FAEIDKKKAEKIArgvdvISLGIGDPDLPTPDhiieAMCKAV--EDPENH-QYPSYEGMLEFRKAVADWYKRRFGVELDP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 85 DSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLV-----LPDF-SIDwqrmaEAIGPRT 158
Cdd:PRK09276 93 ETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLKeengfLPDLdAIP-----EDVAKKA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 159 RLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHD-------ELYprsfvvsSFGKT 231
Cdd:PRK09276 168 KLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPgakdvgiEFH-------SLSKT 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 232 YHVTGWKTGYVVAPPALSAELRKVHQYVNfCGV-TPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLL 300
Cdd:PRK09276 241 YNMTGWRIGFAVGNADLIAGLGKVKSNVD-SGVfQAIQEAGIAALNGPQEVVEELRKIYQERRDILVEGL 309
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
27-376 |
3.01e-33 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 127.90 E-value: 3.01e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQ-YAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAIQAL 105
Cdd:PRK08636 36 IDFSMGNPDGPTPQHIIDKLCESAQKPKTHgYSVSKGIYKLRLAICNWYKRKYNVDLDPETEVVATMGSKEGYVHLVQAI 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 106 VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVL-PDFSIDWQR--------MAEAIgPRTRLVIINTPHNPSGALISR 176
Cdd:PRK08636 116 TNPGDVAIVPDPAYPIHSQAFILAGGNVHKMPLEYnEDFELDEDQffenlekaLRESS-PKPKYVVVNFPHNPTTATVEK 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 177 EELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHD---ELYPRSFVVSsfgKTYHVTGWKTGYVVAPPALSAELR 253
Cdd:PRK08636 195 SFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEVEgakDVAVESYTLS---KSYNMAGWRVGFVVGNKKLVGALK 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 254 KVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSAIRPDLDDVAMA 333
Cdd:PRK08636 272 KIKSWLDYGMFTPIQVAATIALDGDQSCVEEIRETYRKRRDVLIESFANAGWELQKPRASMFVWAKIPEPARHLGSLEFS 351
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 489210460 334 EWLTREHGVAAIPVSVFYEKAPDamrLVRFCYAKREETLRQAA 376
Cdd:PRK08636 352 KQLLTEAKVAVSPGIGFGEYGDE---YVRIALIENENRIRQAA 391
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
27-379 |
3.94e-33 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 127.35 E-value: 3.94e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPP----ELREAVGRhiaAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAI 102
Cdd:PRK08068 35 INLGQGNPDQPTPEhiveALQEAAEN---PANHKYSPFRGYPFLKEAAADFYKREYGVTLDPETEVAILFGGKAGLVELP 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 103 QALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDR 181
Cdd:PRK08068 112 QCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAEnNFLPDYTKIPEEVAEKAKLMYLNYPNNPTGAVATKAFFEE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 182 LAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHD-------ELYprsfvvsSFGKTYHVTGWKTGYVVAPPALSAELRK 254
Cdd:PRK08068 192 TVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPgakdvgiELY-------TLSKTFNMAGWRVAFAVGNESVIEAINL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 255 VHQYVnFCGVTP-LQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFqcvdysAIRP---DLDDV 330
Cdd:PRK08068 265 LQDHL-FVSLFGaIQDAAIEALLSDQSCVAELVARYESRRNAFISACREIGWEVDAPKGSFF------AWMPvpkGYTSE 337
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 489210460 331 AMAEWLTREHGVAAIPVSVFYEKAPdamRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK08068 338 QFADLLLEKAHVAVAPGNGFGEHGE---GYVRVGLLTDEERLREAVERI 383
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
16-376 |
8.42e-33 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 126.72 E-value: 8.42e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 16 RMSQLAAECGA--INLSQGFPDFDGPP----ELREAVGRHIAAGhnqYAPMTGLPALREQVAkkieQFYGRR----VSAD 85
Cdd:PRK09148 20 RLKAAARAAGAdiIDLGMGNPDLPTPQhivdKLCETAQDPRTHR---YSASKGIPGLRRAQA----AYYARRfgvkLNPD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 86 SEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPlVLPDFSIdWQRMAEAIG---PRTRLVI 162
Cdd:PRK09148 93 TQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVP-AEPDEEF-FPALERAVRhsiPKPIALI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 163 INTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYV 242
Cdd:PRK09148 171 VNYPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQVPGAKDVTVEFTSMSKTFSMAGWRMGFA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 243 VAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRdlfcDLLLDSrfrFTRA-------PGTYF 315
Cdd:PRK09148 251 VGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGPQDCIAEMRELYKKRR----DVLVES---FGRAgwdipppAASMF 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489210460 316 QCVDYSAIRPDLDDVAMAEWLTREHGVAAIPVSVFYEKAPDamrLVRFCYAKREETLRQAA 376
Cdd:PRK09148 324 AWAPIPEAFRHLGSLEFSKLLVEKADVAVAPGVGFGEHGDG---YVRIALVENEQRIRQAA 381
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
27-375 |
1.91e-32 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 125.59 E-value: 1.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPP----ELREAVGRhiaAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSAI 102
Cdd:PRK08175 32 IDFSMGNPDGPTPPhiveKLCEVAQR---PDTHGYSTSRGIPRLRRAISRWYQDRYDVDIDPESEAIVTIGSKEGLAHLM 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 103 QALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVlP--DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELD 180
Cdd:PRK08175 109 LATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLV-EgvDFFNELERAIRESYPKPKMMILGFPSNPTAQCVELEFFE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 181 RLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVN 260
Cdd:PRK08175 188 KVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDVAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSYHD 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 261 FCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSAIRPDLDDVAMAEWLTREH 340
Cdd:PRK08175 268 YGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEA 347
|
330 340 350
....*....|....*....|....*....|....*
gi 489210460 341 GVAAIPVSVFYEKAPDamrLVRFCYAKREETLRQA 375
Cdd:PRK08175 348 KVCVSPGIGFGDYGDT---HVRFALIENRDRIRQA 379
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
57-379 |
2.75e-32 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 124.66 E-value: 2.75e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 57 YAPMTGLPALREQVAKKIEqfygrRVSADsEVTITPGATEAIFSAIQALVHPGDEVVVLDPSY-------DSYEPSVQLa 129
Cdd:PRK07324 58 YGWIEGSPEFKEAVASLYQ-----NVKPE-NILQTNGATGANFLVLYALVEPGDHVISVYPTYqqlydipESLGAEVDY- 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 130 ggrcvhvplvLP-----DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVF 204
Cdd:PRK07324 131 ----------WQlkeenGWLPDLDELRRLVRPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 205 DGvahtSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFC-GVtplqwaLADYMAGHP-EHL 282
Cdd:PRK07324 201 DG----STPSIADLYEKGISTNSMSKTYSLPGIRVGWIAANEEVIDILRKYRDYTMICaGV------FDDMLASLAlEHR 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 283 RQLpgfYQAKRDLFCDLL--LDsrfrftrapgtyfQCVD----YSAIRP------------DLDDVAMAEWLTREHGVAA 344
Cdd:PRK07324 271 DAI---LERNRKIVRTNLaiLD-------------EWVAkeprVSYVKPkavstsfvkldvDMPSEDFCLKLLKETGVLL 334
|
330 340 350
....*....|....*....|....*....|....*
gi 489210460 345 IPVSVFyekapDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07324 335 VPGNRF-----DLEGHVRIGYCCDTETLKKGLKKL 364
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
27-379 |
6.60e-32 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 124.37 E-value: 6.60e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQG----FPDFDGPPELREAVGRHIAAG-HNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSA 101
Cdd:TIGR01265 34 IPLSHGdpsvFGNLRTDPEAEEAVKDALRSGkFNGYAPSVGALAAREAVAEYLSSDLPGKLTAD-DVVLTSGCSQAIEIC 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 102 IQALVHPGDEVVVLDPSYDSYEpSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREEL 179
Cdd:TIGR01265 113 IEALANPGANILVPRPGFPLYD-TRAAFSGLEVRLYDLLPEkdWEIDLDGLESLADEKTVAIVVINPSNPCGSVFSRDHL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 180 DRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRsFVVSSFGKTYHVTGWKTGYV-VAPPALSAELRKVHQY 258
Cdd:TIGR01265 192 QKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASIVPV-LSLGGISKRWVVPGWRLGWIiIHDPHGIFRDTVLQGL 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 259 VNFCGVTP-----LQWALADYMAGHPEHlrqlpgFYQAKR-------DLFCDLLLDSR-FRFTRAPGTYFQCV--DYSAI 323
Cdd:TIGR01265 271 KNLLQRILgpatiVQGALPDILENTPQE------FFDGKIsvlksnaELCYEELKDIPgLVCPKPEGAMYLMVklELELF 344
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 489210460 324 RPDLDDVAMAEWLTREHGVAAIPVSVFyeKAPDAMRLVrfcYAKREETLRQAAEKL 379
Cdd:TIGR01265 345 PEIKDDVDFCEKLAREESVICLPGSAF--GLPNWVRIT---ITVPESMLEEACSRI 395
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
36-379 |
1.37e-31 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 123.38 E-value: 1.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 36 FDGPPELREAVGRHI--AAGhnqYAPMTGLPALReqvaKKIEQFYGRR----VSADsEVTITPGATEAIFSAIQALVHPG 109
Cdd:PRK09265 48 FEAPDEILRDVIRNLptAQG---YSDSKGLFSAR----KAIMQYYQQKgipdVDVD-DIYIGNGVSELIVMAMQALLNNG 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 110 DEVVVLDPSYDSYEPSVQLAGGRCVHVplvLPDFSIDWQ----RMAEAIGPRTR-LVIINtPHNPSGALISREELDRLAA 184
Cdd:PRK09265 120 DEVLVPAPDYPLWTAAVSLSGGKPVHY---LCDEEAGWFpdldDIRSKITPRTKaIVIIN-PNNPTGAVYSKELLEEIVE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LIRDRDIYLISDEVYEHLVFDGVAHTSVLShdeLYPRSFVV--SSFGKTYHVTGWKTGYVVappaLSAELRKVHQYVN-- 260
Cdd:PRK09265 196 IARQHNLIIFADEIYDKILYDGAVHISIAS---LAPDLLCVtfNGLSKAYRVAGFRVGWMV----LSGPKKHAKGYIEgl 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 261 -------FCGVTPLQWALADYMAGHpehlrQ------LPG--FYQaKRDLFCDLLLDSrfrftraPGTyfQCVD------ 319
Cdd:PRK09265 269 dmlasmrLCANVPAQHAIQTALGGY-----QsineliLPGgrLYE-QRDRAWELLNAI-------PGV--SCVKpkgaly 333
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489210460 320 -YSAIRPDL----DDVAMAEWLTREHGVAAIPVSVFYEKAPDAMRLVrfcYAKREETLRQAAEKL 379
Cdd:PRK09265 334 aFPKLDPKVypihDDEQFVLDLLLQEKVLLVQGTGFNWPEPDHFRIV---TLPRVDDLEEAIGRI 395
|
|
| hisC |
TIGR01141 |
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ... |
36-255 |
1.91e-30 |
|
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]
Pssm-ID: 273467 Cd Length: 350 Bit Score: 119.30 E-value: 1.91e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 36 FDGPPELREAVGRHIAAGHnQYaPMTGLPALREQVAKkieqFYGrrVSADSeVTITPGATEAIFSAIQALVHPGDEVVVL 115
Cdd:TIGR01141 32 FGPPEKAKEALRAELKKLH-RY-PDPDPAELKQALAD----YYG--VDPEQ-ILLGNGSDEIIDLLIRAFLEPGDAVLVP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 116 DPSYDSYEPSVQLAGGRCVHVPLVlPDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLIs 195
Cdd:TIGR01141 103 PPTYSMYEISAKIHGAEVVKVPLD-EDGQLDLEDILVAIDDKPKLVFLCSPNNPTGNLFSRGDIEAVLERTPGDALVVV- 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 196 DEVYEHlvFDGVAHTSVLSHDelYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKV 255
Cdd:TIGR01141 181 DEAYGE--FSGEPSTLPLLAE--YPNLIVLRTLSKAFGLAGLRIGYAIANAEIIDALNKV 236
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
5-379 |
2.15e-30 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 119.78 E-value: 2.15e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 5 KLPNVGTTIFTRMSQLAAECGA-----INLSQGFPDFDGPPELREAVGRHIAAGHNQ-YAPMTGLPALREQVAKKIEQFY 78
Cdd:PRK07366 6 RLQPLQSNVFADMDRAKAQARAagkelIDLSLGSSDLPAPAHALEAIAQSLHDPSTHgYLLFHGTLDFREAAAQWYEQRF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 79 GRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLV-----LPDFSidwqRMAEA 153
Cdd:PRK07366 86 GLAVDPETEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLRaendfLPVFA----DIPTE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 154 IGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHT-SVLSHDELYPRSFVVSSFGKTY 232
Cdd:PRK07366 162 VLAQARLMVLSYPHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVEPpSILQADPEKSVSIEFFTLSKSY 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 233 HVTGWKTGYVVAPPALSAELRKVHQYVNF---CGVtpLQWALAdYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTR 309
Cdd:PRK07366 242 NMGGFRIGFAIGNAQLIQALRQVKAVVDFnqyRGI--LNGAIA-ALTGPQATVQQTVQIFRQRRDAFINALHQIGWPVPL 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489210460 310 APGTYFqcvdYSAIRPDL---DDVAMAEWLTREHGVAAIPVSVFyekAPDAMRLVRFCYAKREETLRQAAEKL 379
Cdd:PRK07366 319 PEATMY----VWAKLPEPwqgNSVEFCTQLVAQTGVAASPGSGF---GKSGEGYVRFALVHDPDILEEAVERI 384
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
25-256 |
2.96e-29 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 116.22 E-value: 2.96e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFPDFDGPPELREAVGRhIAAGHNQYaPMTGLPALREQVAkkieqfygRRVSADSE-VTITPGATEAIFSAIQ 103
Cdd:PRK03321 23 GAIKLSSNETPFGPLPSVRAAIAR-AAAGVNRY-PDMGAVELRAALA--------EHLGVPPEhVAVGCGSVALCQQLVQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 104 ALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLvLPDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLA 183
Cdd:PRK03321 93 ATAGPGDEVIFAWRSFEAYPILVQVAGATPVQVPL-TPDHTHDLDAMAAAITDRTRLIFVCNPNNPTGTVVTPAELARFL 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489210460 184 ALIrDRDIYLISDEVYEHLVFDGVAHTSV-LSHDelYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVH 256
Cdd:PRK03321 172 DAV-PADVLVVLDEAYVEYVRDDDVPDGLeLVRD--HPNVVVLRTFSKAYGLAGLRVGYAVGHPEVIAALRKVA 242
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
12-379 |
3.66e-29 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 116.81 E-value: 3.66e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 12 TIFTRMSQLAAECGAINLSQGFPDFDG----PPELREAVGRHIAAGH-NQYAPMTGLPALREQVAKKIEQFYGRRVSADS 86
Cdd:PTZ00433 21 TVTDNAKPSPSPKSIIKLSVGDPTLDGnlltPAIQTKALVEAVDSQEcNGYPPTVGSPEAREAVATYWRNSFVHKESLKS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 87 E-----VTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPL-VLPDFSIDWQRMAEAIGPRTRL 160
Cdd:PTZ00433 101 TikkdnVVLCSGVSHAILMALTALCDEGDNILVPAPGFPHYETVCKAYGIEMRFYNCrPEKDWEADLDEIRRLVDDRTKA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 161 VIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRsFVVSSFGKTYHVTGWKTG 240
Cdd:PTZ00433 181 LIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPR-VILGGTAKNLVVPGWRLG 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 241 YVV------APPALSAELRKVHQYVnfCGV-TPLQWALADYMAGHP-EHLRQLPGFYQAKRDLFCDLLLDSR-FRFTRAP 311
Cdd:PTZ00433 260 WLLlvdphgNGGDFLDGMKRLGMLV--CGPcSVVQAALGEALLNTPqEHLEQIVAKLEEGAMVLYNHIGECIgLSPTMPR 337
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 312 GTYFQC--VDYSAIRPDLDDVAMAEWLTREHGVAAIPVSVFYekAPDAMRLVrfcYAKREETLRQAAEKL 379
Cdd:PTZ00433 338 GSMFLMsrLDLEKFRDIKSDVEFYEKLLEEENVQVLPGEIFH--MPGFTRLT---ISRPVEVLREAVERI 402
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
27-379 |
4.06e-29 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 116.42 E-value: 4.06e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDG----PPELREAVGRHIAAG-HNQYAPMTGLPALREQVAKkieqfYGRRVSAD---SEVTITPGATEAI 98
Cdd:TIGR01264 34 IKLSIGDPTVFGnlptDPEVMQAMKDSLDSGkYNGYAPTVGALSAREAIAS-----YYHNPDGPieaDDVVLCSGCSHAI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 99 FSAIQALVHPGDEVVVLDPSYDSYEpSVQLAGGRCVHVPLVLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISR 176
Cdd:TIGR01264 109 EMCIAALANAGQNILVPRPGFPLYE-TLAESMGIEVKLYNLLPDksWEIDLKQLESLIDEKTAALIVNNPSNPCGSVFSR 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 177 EELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRsFVVSSFGKTYHVTGWKTGY--VVAPPALSAE--- 251
Cdd:TIGR01264 188 QHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPI-LSCGGLAKRWLVPGWRLGWiiIHDRRGILRDird 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 252 -LRKVHQYVnfCG-VTPLQWALADYMAGHP-EHLRQLPGFYQAKRDLFCDLLLDSR-FRFTRAPGTYFQCVDYSAIR-PD 326
Cdd:TIGR01264 267 gLVKLSQRI--LGpCTIVQGALPSILLRTPqEYFDGTLSVLESNAMLCYGALAAVPgLRPVMPSGAMYMMVGIEMEHfPE 344
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 489210460 327 L-DDVAMAEWLTREHGVAAIPVSVFyeKAPDAMRLVRFCyakREETLRQAAEKL 379
Cdd:TIGR01264 345 FkNDVEFTERLVAEQSVFCLPGSCF--EYPGFFRVVLTV---PVVMMEEACSRI 393
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
4-379 |
1.85e-27 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 113.29 E-value: 1.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 4 SKLPNV-----GTTIFTRMSQLAAECGAINLSQGFP---DFDGPPELREAVGRHI--AAGhnqYAPMTGLPALReqvaKK 73
Cdd:PRK13355 121 HKLDNVlydvrGPVVDEANRMEAAGTHILKLNIGNPapfGFRTPDEVVYDMAQQLtdTEG---YSDSKGLFSAR----KA 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 74 IEQFYGRR----VSADsEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVplvLPDFSIDWQ- 148
Cdd:PRK13355 194 IMQYAQLKglpnVDVD-DIYTGNGVSELINLSMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHY---RCDEQSEWYp 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 149 ---RMAEAIGPRTR-LVIINtPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLShdeLYPRSFV 224
Cdd:PRK13355 270 didDIRSKITSRTKaIVIIN-PNNPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIAS---LAPDLFC 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 225 VSSFG--KTYHVTGWKTGYVVappaLSAELRKVHQYV---------NFCGVTPLQWALADYMAGHpEHLRQL--PG--FY 289
Cdd:PRK13355 346 VTFSGlsKSHMIAGYRIGWMI----LSGNKRIAKDYIeglnmlanmRLCSNVPAQSIVQTALGGH-QSVKDYlvPGgrVY 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 290 QaKRDLFCDLLLDSRFRFTRAPGTYFQC---VDYSaIRPDLDDVAMAEWLTREHGVAAIPVSVFYEKAPDAMRLVrfcYA 366
Cdd:PRK13355 421 E-QRELVYNALNAIPGISAVKPKAAFYIfpkIDVK-KFNIHDDEQFALDLLHDKKVLIVQGTGFNWDKPDHFRVV---YL 495
|
410
....*....|...
gi 489210460 367 KREETLRQAAEKL 379
Cdd:PRK13355 496 PRLEDLEDAMDRL 508
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
39-254 |
3.19e-26 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 108.30 E-value: 3.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 39 PPELREAVGRHIAAG-HNQYAPMTGLPALREQVAKKIEqfygrrvSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDP 117
Cdd:PRK06225 43 HEEVREAMIRCIEEGeYCKYPPPEGFPELRELILKDLG-------LDDDEALITAGATESLYLVMRAFLSPGDNAVTPDP 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 118 SYDSYEPSVQLAGGRCVHVPLVLP--DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLIS 195
Cdd:PRK06225 116 GYLIIDNFASRFGAEVIEVPIYSEecNYKLTPELVKENMDENTRLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLH 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 196 DEVYEHLVFDgvaHTSVLSHDelyP-RSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRK 254
Cdd:PRK06225 196 DCTYRDFARE---HTLAAEYA---PeHTVTSYSFSKIFGMAGLRIGAVVATPDLIEVVKS 249
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
14-348 |
7.04e-26 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 107.27 E-value: 7.04e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 14 FTRMSQL------AAECGAINLSQGFPDFDGPPELREAVGRHIAaGHNQYaPMT-GLPALREQVAKKIEQFYG-RRVSAD 85
Cdd:PRK09147 13 FEKLRALfagvtpPADLPPISLSIGEPKHPTPAFIKDALAANLD-GLASY-PTTaGLPALREAIAAWLERRYGlPALDPA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 86 SEVTITPGATEAIFSAIQALVHPGDE---VVVLDPSYDSYEPSVQLAGGRCVHVPLvLP--DFSIDWQRMAEAIGPRTRL 160
Cdd:PRK09147 91 TQVLPVNGSREALFAFAQTVIDRDGPgplVVCPNPFYQIYEGAALLAGAEPYFLNC-DPanNFAPDFDAVPAEVWARTQL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 161 VIINTPHNPSGALISREELDRLAALiRDRDIYLI-SDEVYEHLVFDG---------VAHTsvLSHDElYPRSFVVSSFGK 230
Cdd:PRK09147 170 LFVCSPGNPTGAVLPLDDWKKLFAL-SDRYGFVIaSDECYSEIYFDEaapplglleAAAE--LGRDD-FKRLVVFHSLSK 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 231 TYHVTGWKTGYVVAPPALsaeLRKVHQYVNFCG-VTPLQWALADYMA----GHPEHLRQLpgfYQAKRDLFCDLL---LD 302
Cdd:PRK09147 246 RSNVPGLRSGFVAGDAAL---LKKFLLYRTYHGcAMPPAVQAASIAAwndeAHVRENRAL---YREKFDAVTPILapvLD 319
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489210460 303 srfrfTRAPGTYFqcvdYSAIRPDLDDVAMAEWLTREHGVAAIPVS 348
Cdd:PRK09147 320 -----VQLPDAGF----YLWAKVPGDDTEFARRLYADYNVTVLPGS 356
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
4-300 |
2.19e-23 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 100.18 E-value: 2.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 4 SKLPnvgTTIFTRMSQLAA---ECGA--INLSQGFPDFDGPPELREAVgrhIAA----GHNQYAPMTGLPALREQVAKKI 74
Cdd:PRK05942 13 QALP---PYVFARLDELKArarEQGLdlIDLGMGNPDGAAPQPVIEAA---IAAladpQNHGYPPFEGTASFRQAITDWY 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 75 EQFYGRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRcVHvPLVLP---DFSIDWQRMA 151
Cdd:PRK05942 87 HRRYGVELDPDSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHFRGPLIAGAQ-IY-PIILKpenDWLIDLSSIP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 152 EAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKT 231
Cdd:PRK05942 165 EEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHTLSKT 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489210460 232 YHVTGWKTGYVVAPPALSAELRKVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDLFCDLL 300
Cdd:PRK05942 245 YNMAGWRVGFVVGNRHIIQGLRTLKTNLDYGIFSALQKAAETALQLPDSYLQQVQERYRTRRDFLIQGL 313
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
26-382 |
5.70e-23 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 99.45 E-value: 5.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 26 AINLSQGfpDFDG----PPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSEVTITPGATEAIFSA 101
Cdd:PRK06207 41 PVDFSHG--DVDAheptPGAFELFSAGVERGGVQAYTEYRGDADIRELLAARLAAFTGAPVDAADELIITPGTQGALFLA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 102 IQALVHPGDEVVVLDPSYDSYEPSVQLAGGrcVHVPLVLPDFS------IDWQRMAEAIGPRTRLVIINTPHNPSGALIS 175
Cdd:PRK06207 119 VAATVARGDKVAIVQPDYFANRKLVEFFEG--EMVPVQLDYLSadkragLDLDQLEEAFKAGVRVFLFSNPNNPAGVVYS 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 176 REELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSVLSHDElyPRSFVVSSFG--KTYHVTGWKTGYVVAPPALSAELR 253
Cdd:PRK06207 197 AEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPI--DPENVITIMGpsKTESLSGYRLGVAFGSPAIIDRME 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 254 KVHQYVNFCGVTPLQWALADYMAGHPEHLRQLPGFYQAKRDlfcDLLldSRFR-----FTRAP--GTYfqcvdysaIRPD 326
Cdd:PRK06207 275 KLQAIVSLRAAGYSQAVLRTWFSEPDGWMKDRIARHQAIRD---DLL--RVLRgvegvFVRAPqaGSY--------LFPR 341
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489210460 327 LD--DVAMAEW---LTREHGVAAIPVSVFYEKAPDAMRLvrfCYAKREETLRQAAEKLCAI 382
Cdd:PRK06207 342 LPrlAVSLHDFvkiLRLQAGVIVTPGTEFSPHTADSIRL---NFSQDHAAAVAAAERIAQL 399
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
27-379 |
6.35e-21 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 93.56 E-value: 6.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYG-RRVSADSEVTITPGATEAIFSAIQAL 105
Cdd:PRK06290 47 IDMGVGEPDEMADESVVEVLCEEAKKPENRGYADNGIQEFKEAAARYMEKVFGvKDIDPVTEVIHSIGSKPALAMLPSCF 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 106 VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLV-----LPDFSidwqRMAEAIGPRTRLVIINTPHNPSGALISREELD 180
Cdd:PRK06290 127 INPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPLLeennfLPDLD----SIPKDIKEKAKLLYLNYPNNPTGAVATKEFYE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 181 RLAALIRDRDIYLISDEVYEHLVFDGvAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVN 260
Cdd:PRK06290 203 EVVDFAKENNIIVVQDAAYAALTFDG-KPLSFLSVPGAKEVGVEIHSLSKAYNMTGWRLAFVVGNELIVKAFATVKDNND 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 261 FCGVTPLQWALAdYMAGHPEHLRQLPGFYQAKRDLFCDLLLDSRFRFTRAPGTYFQCVDYSAIRPDLDDVAMAE----WL 336
Cdd:PRK06290 282 SGQFIAIQKAGI-YALDHPEITEKIREKYSRRLDKLVKILNEVGFKAEMPGGTFYLYVKAPKGTKSGIKFENAEefsqYL 360
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489210460 337 TREHGVAAIPVSvfyekapDAMRLVRF--CY-AKREETLRQAAEKL 379
Cdd:PRK06290 361 IKEKLISTVPWD-------DAGHFLRFsvTFeAKDEEEEDRILEEI 399
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
33-244 |
5.01e-19 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 87.90 E-value: 5.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 33 FPDFDGPPELREAVGRHIAAG-HNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGDE 111
Cdd:PLN00145 65 FPCFRTAPEAEDAVAAALRSGkYNSYSTCVGLLPARRAIAEYLSRDLPYELSTD-DIYLTAGCAQAIEIIMSVLAQPGAN 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 112 VVVLDPSYDSYEPSVQLAGGRCVHVPLvLPD--FSIDWQRMaEAIGPR--TRLVIINtPHNPSGALISREELDRLAALIR 187
Cdd:PLN00145 144 ILLPRPGYPLYEARAVFSGLEVRHFDL-LPErgWEVDLEGV-EALADEntVAMVIIN-PNNPCGSVYSYEHLAKIAETAR 220
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 489210460 188 DRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPrSFVVSSFGKTYHVTGWKTGYVVA 244
Cdd:PLN00145 221 KLGILVIADEVYDHLTFGSKPFVPMGVFGEVAP-VLTLGSISKRWVVPGWRLGWIAT 276
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
55-243 |
1.19e-17 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 83.82 E-value: 1.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 55 NQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCV 134
Cdd:PLN02656 67 NGYAPTVGLPQARRAIAEYLSRDLPYKLSLD-DVFITSGCTQAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVR 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 135 HVPLvLPD--FSIDWQRMaEAIGPRTR--LVIINtPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHT 210
Cdd:PLN02656 146 YVDL-LPEkgWEVDLDAV-EALADQNTvaLVIIN-PGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFV 222
|
170 180 190
....*....|....*....|....*....|...
gi 489210460 211 SVLSHDELYPrSFVVSSFGKTYHVTGWKTGYVV 243
Cdd:PLN02656 223 PMGVFGSIVP-VLTLGSLSKRWIVPGWRLGWFV 254
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
32-243 |
2.16e-15 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 76.97 E-value: 2.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 32 GFPDFDGPPELREA-VGRHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGD 110
Cdd:PLN00143 44 CFECFRTTNIAEDAiVEAVRSAKFNSYAPTGGILPARRAIADYLSNDLPYQLSPD-DVYLTLGCKHAAEIIIKVLARPEA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 111 EVVVLDPSYDSYEPSVQLAGGRCVHVPLvLPD--FSIDWQRMaEAIGPRTR--LVIINtPHNPSGALISREELDRLAALI 186
Cdd:PLN00143 123 NILLPRPGFPDVETYAIFHHLEIRHFDL-LPEkgWEVDLDAV-EAIADENTiaMVIIN-PGNPCGSVYSYEHLNKIAETA 199
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 489210460 187 RDRDIYLISDEVYEHLVFDGVAHTSVLSHDELYPrSFVVSSFGKTYHVTGWKTGYVV 243
Cdd:PLN00143 200 RKLGILVIADEVYGHIVFGSKPFVPMGLFASIVP-VITLGSISKRWMIPGWGLGWLV 255
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
48-206 |
8.77e-15 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 75.39 E-value: 8.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 48 RHIAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSADSeVTITPGATEAIFSAIQALV-HPGDEVVVLDPSYDSYEPSV 126
Cdd:PTZ00377 102 NAIGGGTGAYTDSAGYPFVRKAVAAFIERRDGVPKDPSD-IFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYPLYSAAI 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 127 QLAGGRCVHVPLVLPD-FSIDWQRMAEA--------IGPRTrLVIINtPHNPSGALISREELDRLAALIRDRDIYLISDE 197
Cdd:PTZ00377 181 TLLGGKQVPYYLDEEKgWSLDQEELEEAyeqavrngITPRA-LVVIN-PGNPTGQVLTRDVMEEIIKFCYEKGIVLMADE 258
|
....*....
gi 489210460 198 VYEHLVFDG 206
Cdd:PTZ00377 259 VYQENIYDG 267
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
14-284 |
2.71e-14 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 73.57 E-value: 2.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 14 FTRMSQLAA------ECGAINLSQGFPDFDGPPELREAVGRHiAAGHNQYAPMTGLPALREQVAKKIEQFYGRRVSaDSE 87
Cdd:PRK05839 8 FEKLRELLKeitpnkEYKGLDLTIGEPQFETPKFIQDALKNN-AHLLNKYPKSAGEESLREAQRGFFKRRFKIELK-ENE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 88 VTITPGATEAIFSAIQALVH--PGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLP-DF--SIDWQRMAEAigprtRLVI 162
Cdd:PRK05839 86 LIPTFGTREVLFNFPQFVLFdkQNPTIAYPNPFYQIYEGAAIASRAKVLLMPLTKEnDFtpSLNEKELQEV-----DLVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 163 INTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFD----GVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWK 238
Cdd:PRK05839 161 LNSPNNPTGRTLSLEELIEWVKLALKHDFILINDECYSEIYENtpppSLLEASILVGNESFKNVLVINSISKRSSAPGLR 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 489210460 239 TGYVvappALSAE-LRKVHQYVNFCGVT---PLQWALADYMAG--HPEHLRQ 284
Cdd:PRK05839 241 SGFI----AGDASiLKKYKAYRTYLGCAsplPLQKAAAVAWLDdeHAEFFRN 288
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
93-248 |
5.49e-14 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 72.42 E-value: 5.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 93 GATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLvLPDFSIDWQRMAEAIG-PRTRLVIINTPHNPSG 171
Cdd:PLN03026 111 GADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEVIKVPR-TPDFSLDVPRIVEAVEtHKPKLLFLTSPNNPDG 189
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489210460 172 ALISREELDRLAALirdrDIYLISDEVYEHLVFDGVAHTSVLSHDELyprsFVVSSFGKTYHVTGWKTGYVVAPPAL 248
Cdd:PLN03026 190 SIISDDDLLKILEL----PILVVLDEAYIEFSTQESRMKWVKKYDNL----IVLRTFSKRAGLAGLRVGYGAFPLSI 258
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
66-243 |
1.96e-13 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 67.79 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 66 LREQVAKKIEQFYGrrvSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDS-YEPSVQLAGGRCVHVP-LVLPDF 143
Cdd:cd01494 1 KLEELEEKLARLLQ---PGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSrYWVAAELAGAKPVPVPvDDAGYG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 144 SIDWQRMAE-AIGPRTRLVIINTPHNPSGALISREELDRLAAlirDRDIYLISDEVYehlvfdGVAHTSVLSHDELY-PR 221
Cdd:cd01494 78 GLDVAILEElKAKPNVALIVITPNTTSGGVLVPLKEIRKIAK---EYGILLLVDAAS------AGGASPAPGVLIPEgGA 148
|
170 180
....*....|....*....|..
gi 489210460 222 SFVVSSFGKTYHVTGwkTGYVV 243
Cdd:cd01494 149 DVVTFSLHKNLGGEG--GGVVI 168
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
62-242 |
2.70e-13 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 70.69 E-value: 2.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 62 GLPALREQVAKKIEQFYGRRVSADSE-VTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGrcVHVPLVL 140
Cdd:PLN02607 96 GLKSFRQAMASFMEQIRGGKARFDPDrIVLTAGATAANELLTFILADPGDALLVPTPYYPGFDRDLRWRTG--VKIVPIH 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 141 PDFSIDWQ----------RMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHT 210
Cdd:PLN02607 174 CDSSNNFQvtpqaleaayQEAEAANIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSASEFV 253
|
170 180 190
....*....|....*....|....*....|....*...
gi 489210460 211 SV------LSHDELYPRSFVVSSFGKTYHVTGWKTGYV 242
Cdd:PLN02607 254 SVaeiveaRGYKGVAERVHIVYSLSKDLGLPGFRVGTI 291
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
45-311 |
4.03e-13 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 69.78 E-value: 4.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 45 AVGRHIAAGHNQYA--PMTGLPALREQVAkkieqfygRRVSADSEVTITPGATEAIFSAI-QALVHPGDEVVVLDPSYDS 121
Cdd:PRK05166 53 AVRRAFADIAELLRlyPDPQGRALREAIA--------ARTGVPADRIILGNGSEDLIAVIcRAVLRPGDRVVTLYPSFPL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 122 YEPSVQLAGGRCVHVPlVLPDFSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIrDRDIYLISDEVY-E 200
Cdd:PRK05166 125 HEDYPTMMGARVERVT-VTPDLGFDLDALCAAVARAPRMLMFSNPSNPVGSWLTADQLARVLDAT-PPETLIVVDEAYaE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 201 HLVFDGVAHTSVLSHDELYPRsFVVSSFGKTYHVTGWKTGY-VVAPPALSAELRKVHQYVNFCGVTpLQWALADYmaGHP 279
Cdd:PRK05166 203 YAAGDDYPSALTLLKARGLPW-IVLRTFSKAYGLAGLRVGYgLVSDPELVGLLDRVRTPFNVNGAA-QAAALAAL--DDE 278
|
250 260 270
....*....|....*....|....*....|..
gi 489210460 280 EHLRQLPGFYQAKRDLFCDLLLDSRFRFtrAP 311
Cdd:PRK05166 279 EHLAKGVALALAERERLKKELAEMGYRI--AP 308
|
|
| PRK09105 |
PRK09105 |
pyridoxal phosphate-dependent aminotransferase; |
38-272 |
4.69e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181651 Cd Length: 370 Bit Score: 69.69 E-value: 4.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 38 GP-PELREAVGRHIAAGhNQYapmtgLPALREQVAKKIEQFYGrrVSADSeVTITPGATEAIFSAIQALVHPGDEVVVLD 116
Cdd:PRK09105 56 GPsPAARDAAARSAALS-GRY-----DLELEDDLRTLFAAQEG--LPADH-VMAYAGSSEPLNYAVLAFTSPTAGLVTAD 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 117 PSYDSYEPSVQLAGGRCVHVPLVlPDFSIDWQRMAEAiGPRTRLVIINTPHNPSGALISREELDRLAALiRDRDIYLISD 196
Cdd:PRK09105 127 PTYEAGWRAADAQGAPVAKVPLR-ADGAHDVKAMLAA-DPNAGLIYICNPNNPTGTVTPRADIEWLLAN-KPAGSVLLVD 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 197 EVYEHLvFDGvahTSVLS----HDELyprsFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQyvNFCGVTPLQWALA 272
Cdd:PRK09105 204 EAYIHF-SDA---PSVVDlvaqRKDL----IVLRTFSKLYGMAGMRLGLAAARPDLLAKLARFGH--NPLPVPAAAAGLA 273
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
62-240 |
7.06e-13 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 69.78 E-value: 7.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 62 GLPALREQVAKKIEQFYGRRVSADSE-VTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVhVPL-- 138
Cdd:PLN02450 87 GLPAFKNALAEFMSEIRGNKVTFDPNkLVLTAGATSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKWRTGVEI-VPIhc 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 139 -VLPDFSI------DWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTS 211
Cdd:PLN02450 166 sSSNGFQItesaleEAYQQAQKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSPGFVS 245
|
170 180 190
....*....|....*....|....*....|....*..
gi 489210460 212 V--------LSHDELYPRSFVVSSFGKTYHVTGWKTG 240
Cdd:PLN02450 246 VmevlkdrkLENTDVSNRVHIVYSLSKDLGLPGFRVG 282
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
53-204 |
1.86e-12 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 67.90 E-value: 1.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 53 GHNQYAPMTGLPALREQVAKKIEQFYGrrVSADSE-VTITPGATEAIFSAIQALV-HPGDEVVVLDPSYDSYEPSVQLAG 130
Cdd:PLN02368 99 GLGAYSDSRGLPGVRKEVAEFIERRDG--YPSDPElIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQYPLYSATISLLG 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 131 GRCVhvPLVLpDFSIDW--------QRMAEA----IGPRTrLVIINtPHNPSGALISREELDRLAALIRDRDIYLISDEV 198
Cdd:PLN02368 177 GTLV--PYYL-EESENWgldvnnlrQSVAQArskgITVRA-MVIIN-PGNPTGQCLSEANLREILKFCYQERLVLLGDEV 251
|
....*.
gi 489210460 199 YEHLVF 204
Cdd:PLN02368 252 YQQNIY 257
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
33-302 |
8.98e-12 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 66.29 E-value: 8.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 33 FPDFDGPPELREAVGRHIAAGH-NQYAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGDE 111
Cdd:PLN02187 79 YPCFRTCIEAEDAVVDVLRSGKgNSYGPGAGILPARRAVADYMNRDLPHKLTPE-DIFLTAGCNQGIEIVFESLARPNAN 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 112 VVVLDPSYDSYEPSVQLAGGRCVHVPLvLPD--FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDR 189
Cdd:PLN02187 158 ILLPRPGFPHYDARAAYSGLEVRKFDL-LPEkeWEIDLEGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKVAETARKL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 190 DIYLISDEVYEHLVFDGVAHTSVLSHDELYPrSFVVSSFGKTYHVTGWKTGYV-VAPPALSAELRKVHQYV-NFCGVTPL 267
Cdd:PLN02187 237 GIMVISDEVYDRTIFGDNPFVSMGKFASIVP-VLTLAGISKGWVVPGWKIGWIaLNDPEGVFETTKVLQSIkQNLDVTPD 315
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 489210460 268 QWALADymAGHPEHLRQLPGFYQAKR--------DLFCDLLLD 302
Cdd:PLN02187 316 PATIIQ--AALPAILEKADKNFFAKKnkilkhnvDLVCDRLKD 356
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
62-212 |
1.28e-10 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 62.79 E-value: 1.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 62 GLPALREQVAKKIEQFYGRRVSADSE-VTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGG-RCVHVPLV 139
Cdd:PLN02376 95 GLKKFRQAIAHFMGKARGGKVTFDPErVVMSGGATGANETIMFCLADPGDVFLIPSPYYAAFDRDLRWRTGvEIIPVPCS 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 140 LPD---FSID---WQ-RMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTSV 212
Cdd:PLN02376 175 SSDnfkLTVDaadWAyKKAQESNKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGGDFVSV 254
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
68-242 |
2.15e-10 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 61.28 E-value: 2.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 68 EQVAKKIEQFYGRrvsadsEVTITPGATEAiFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLvlpdfsiDW 147
Cdd:PRK08354 43 EWLEEEFSKLFGE------PIVITAGITEA-LYLIGILALRDRKVIIPRHTYGEYERVARFFAARIIKGPN-------DP 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 148 QRMAEAIGPRTrLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVYehlvFDGVAHTSVLSHDELyprsFVVSS 227
Cdd:PRK08354 109 EKLEELVERNS-VVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAF----IDFVKKPESPEGENI----IKLRT 179
|
170
....*....|....*
gi 489210460 228 FGKTYHVTGWKTGYV 242
Cdd:PRK08354 180 FTKSYGLPGIRVGYV 194
|
|
| PRK15481 |
PRK15481 |
transcriptional regulatory protein PtsJ; Provisional |
10-300 |
8.73e-10 |
|
transcriptional regulatory protein PtsJ; Provisional
Pssm-ID: 185378 [Multi-domain] Cd Length: 431 Bit Score: 60.06 E-value: 8.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 10 GTTIFTRMSQLAAECGA-----INLSQGFPDFDGPPELREAvgrhiaAGHNQYAP-MTGLPALREQVAKKIEQFYGRRVS 83
Cdd:PRK15481 66 GTVIRGSPSPVALEGGDpgtplHDLAGGNPDPQRLPDLSRY------FARLSRTPrLYGDAPVSPELHAWAARWLRDDCP 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 84 ADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPlvlpdfsIDWQRM-----AEAIGPRT 158
Cdd:PRK15481 140 VAFEIDLTSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVS-------VDAEGMqpeklERALAQGA 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 159 RLVIInTP--HNPSGALISREELDRLAALI-RDRDIYLISDEVYEHLvfDGVAHTSVLSHDElyPRSFVVSSFGKTYhvt 235
Cdd:PRK15481 213 RAVIL-TPraHNPTGCSLSARRAAALRNLLaRYPQVLVIIDDHFALL--SSSPYHSVIPQTT--QRWALIRSVSKAL--- 284
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489210460 236 G--WKTGYVVAPPALSAELRKV----HQYVNFCgvtpLQWALADYMAgHPEHLRQLPG---FYQAKRDLFCDLL 300
Cdd:PRK15481 285 GpdLRLAFVASDSATSARLRLRlnsgTQWVSHL----LQDLVYACLT-DPEYQARLAQarlFYAQRRQKLARAL 353
|
|
| PRK07908 |
PRK07908 |
threonine-phosphate decarboxylase; |
37-252 |
1.76e-09 |
|
threonine-phosphate decarboxylase;
Pssm-ID: 236128 Cd Length: 349 Bit Score: 58.48 E-value: 1.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 37 DGPPE-LREavgrHIAAGHNQYA--PMTGLP-ALREQVAkkieQFYGRRVSadsEVTITPGATEAiFSAIQALvhPGDEV 112
Cdd:PRK07908 34 DTPPEwLRE----RLAARLGDLAayPSTEDErRARAAVA----ARHGRTPD---EVLLLAGAAEG-FALLARL--RPRRA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 113 VVLDPSYDsyEPSVQL-AGGRCVHVPLVLPDFSIDwqrmAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRdrdi 191
Cdd:PRK07908 100 AVVHPSFT--EPEAALrAAGIPVHRVVLDPPFRLD----PAAVPDDADLVVIGNPTNPTSVLHPAEQLLALRRPGR---- 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489210460 192 YLISDEVYehlvFDGVAH-TSVLSHDELyPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAEL 252
Cdd:PRK07908 170 ILVVDEAF----ADAVPGePESLAGDDL-PGVLVLRSLTKTWSLAGLRVGYALGAPDVLARL 226
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
68-196 |
3.99e-09 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 57.64 E-value: 3.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 68 EQVAKKIEQFYGrrVSADSEVTITPGATEAIFSAIQAL---VHPGDEVVVLDPSYDS-YEPSVQLA--GGRCVHVPLVLP 141
Cdd:pfam00266 46 EEAREKVAEFIN--APSNDEIIFTSGTTEAINLVALSLgrsLKPGDEIVITEMEHHAnLVPWQELAkrTGARVRVLPLDE 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 489210460 142 DFSIDWQRMAEAIGPRTRLVIINTPHNPSGALIsreELDRLAALIRDRDIYLISD 196
Cdd:pfam00266 124 DGLLDLDELEKLITPKTKLVAITHVSNVTGTIQ---PVPEIGKLAHQYGALVLVD 175
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
57-262 |
9.18e-09 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 56.87 E-value: 9.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 57 YAPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHP-GDEVVVLDPSYDSYEPSVQLAGGRCVh 135
Cdd:PLN02231 164 YSHSQGIKGLRDAIAAGIEARDGFPADPN-DIFLTDGASPAVHMMMQLLIRSeKDGILCPIPQYPLYSASIALHGGTLV- 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 136 vPLVLpDFSIDW--------QRMAEA----IGPRTrLVIINtPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLV 203
Cdd:PLN02231 242 -PYYL-DEATGWgleiselkKQLEDArskgITVRA-LVVIN-PGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENV 317
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489210460 204 ---------FDGVAHTSVLSHDELYPRSFvvSSFGKTYHVTGWKTGYVVAPPALSAELR----KVHQyVNFC 262
Cdd:PLN02231 318 yvpdkkfhsFKKVARSMGYGEKDISLVSF--QSVSKGYYGECGKRGGYMEVTGFTSDVReqiyKVAS-VNLC 386
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
65-163 |
2.32e-08 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 55.53 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 65 ALREQVAKKIEQFYGrrVSADSEVTITPGATEAIFSAIQAL--VHPGDEVVVLDpsydsYE-PSVQLA--------GGRC 133
Cdd:COG0520 59 DAYEAAREKVARFIG--AASPDEIIFTRGTTEAINLVAYGLgrLKPGDEILITE-----MEhHSNIVPwqelaertGAEV 131
|
90 100 110
....*....|....*....|....*....|
gi 489210460 134 VHVPLvLPDFSIDWQRMAEAIGPRTRLVII 163
Cdd:COG0520 132 RVIPL-DEDGELDLEALEALLTPRTKLVAV 160
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
25-199 |
2.50e-08 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 55.25 E-value: 2.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 25 GAINLSQGFP---------------DFDGPPELREAVGRhiaaghnqYAPMTGLPALREQVAKKIEQFYGRRVSADSeVT 89
Cdd:PRK09440 31 GAIMLGGGNPahipemedyfrdllaDLLASGKLTEALGN--------YDGPQGKDELIEALAALLNERYGWNISPQN-IA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 90 ITPGATEAIFSAIQALVHPGDE------VVVLDPSYDSYEpSVQLAGGRCV-HVPLV--LPD----FSIDWQRMAeaIGP 156
Cdd:PRK09440 102 LTNGSQSAFFYLFNLFAGRRADgslkkiLFPLAPEYIGYA-DAGLEEDLFVsYRPNIelLPEgqfkYHVDFEHLH--IDE 178
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 489210460 157 RTRLVIINTPHNPSGALISREELDRLAALIRDRDIYLISDEVY 199
Cdd:PRK09440 179 DTGAICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDNAY 221
|
|
| PRK02610 |
PRK02610 |
histidinol-phosphate transaminase; |
33-270 |
5.26e-08 |
|
histidinol-phosphate transaminase;
Pssm-ID: 235053 Cd Length: 374 Bit Score: 54.34 E-value: 5.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 33 FPdFDGPPELREAVGRHIAAG--HNQYaPMTGLPALREQVAKKIEQFYGRRVSADSE-VTITPGATEAIFSAIQALVHPG 109
Cdd:PRK02610 38 FP-YDLPPDLKQKLAWLYQQGieSNRY-PDGGHEALKQAIAEYVNESAAGSSQITPAnISVGNGSDELIRSLLIATCLGG 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 110 D-EVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAI----GPRTRLVIINTPHNPSGALISREELDRLAA 184
Cdd:PRK02610 116 EgSILVAEPTFSMYGILAQTLGIPVVRVGRDPETFEIDLAAAQSAIeqtqNPPVRVVFVVHPNSPTGNPLTAAELEWLRS 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 185 LirDRDIYLISDEVYehlvFDGVAHTSVlshDEL--YPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKVHQYVNFC 262
Cdd:PRK02610 196 L--PEDILVVIDEAY----FEFSQTTLV---GELaqHPNWVILRTFSKAFRLAAHRVGYAIGHPELIAVLEKVRLPYNLP 266
|
....*...
gi 489210460 263 GVTplQWA 270
Cdd:PRK02610 267 SFS--QLA 272
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
97-196 |
1.49e-07 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 52.97 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 97 AIFSAIQALVHPGDEVVVLDpsyDSYEPSVQLAGgrcvhvpLVLPDFSI--------DWQRMAEAIGPRTRLVIINTPHN 168
Cdd:cd00614 67 AISTVLLALLKAGDHVVASD---DLYGGTYRLFE-------RLLPKLGIevtfvdpdDPEALEAAIKPETKLVYVESPTN 136
|
90 100
....*....|....*....|....*...
gi 489210460 169 PSGALIsreELDRLAALIRDRDIYLISD 196
Cdd:cd00614 137 PTLKVV---DIEAIAELAHEHGALLVVD 161
|
|
| PRK03317 |
PRK03317 |
histidinol-phosphate aminotransferase; Provisional |
39-255 |
4.11e-07 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 235115 Cd Length: 368 Bit Score: 51.40 E-value: 4.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 39 PPELREAVG---RHIAAGHNQYaPMTGLPALREQVAKKIEQFYGRRVSADsEVTITPGATEAIFSAIQALVHPGDEVVVL 115
Cdd:PRK03317 41 SPALVADIAeavAEAAAGLNRY-PDRDAVALRADLAAYLTAQTGVGLTVE-NVWAANGSNEILQQLLQAFGGPGRTALGF 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 116 DPSYDSYePsvQLAGG---RCVHVPLVlPDFSIDWQRMAEAIGPRT-RLVIINTPHNPSGALISreeLDRLAALIRDRDI 191
Cdd:PRK03317 119 VPSYSMH-P--IIARGthtEWVEGPRA-ADFTLDVDAAVAAIAEHRpDVVFLTSPNNPTGTALP---LDDVEAILDAAPG 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489210460 192 YLISDEVYEHLVFDGVahTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKV 255
Cdd:PRK03317 192 IVVVDEAYAEFRRSGT--PSALTLLPEYPRLVVSRTMSKAFAFAGGRLGYLAAAPAVVDALRLV 253
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
162-211 |
1.45e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 49.95 E-value: 1.45e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 489210460 162 IINtPHNPSGALISREELDRLAALIRDRDIYLISDEVYEHLVFDGVAHTS 211
Cdd:PRK06855 177 LIN-PDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVP 225
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
75-244 |
2.97e-06 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 49.09 E-value: 2.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 75 EQFYGRRVSADSEVTITPGATEA---IFSAIQA--LVHPGDEVVVLDPSYDSYepsvqlaggrcVHVPlVLPDF------ 143
Cdd:PRK09275 151 EMCGGRPPKGEFDLFAVEGGTAAmcyIFDSLKEngLLKAGDKIALMTPIFTPY-----------LEIP-ELPRYdlevvh 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 144 -----SIDWQRMAEAI----GPRTRLVIINTPHNPSGALISREELDRLAALIRDR--DIYLISDEVYEHLVFDGVAHTSV 212
Cdd:PRK09275 219 inadeENEWQYPDSELeklrDPSIKALFLVNPSNPPSVAMSDESLEKIADIVNEKrpDLMIITDDVYGTFVDDFRSLFAV 298
|
170 180 190
....*....|....*....|....*....|..
gi 489210460 213 LSHDELyprsfVVSSFGKTYHVTGWKTGyVVA 244
Cdd:PRK09275 299 LPYNTI-----LVYSFSKYFGATGWRLG-VIA 324
|
|
| PRK08153 |
PRK08153 |
pyridoxal phosphate-dependent aminotransferase; |
105-294 |
8.94e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181255 Cd Length: 369 Bit Score: 47.30 E-value: 8.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 105 LVHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVlpDFSIDWQRMAEAIGP-RTRLVIINTPHNPSGaliSREELDRLA 183
Cdd:PRK08153 104 YVEPGDPVVTSLGAYPTFNYHVAGFGGRLVTVPYR--DDREDLDALLDAARReNAPLVYLANPDNPMG---SWHPAADIV 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 184 ALIRD--RDIYLISDEVYEHLVFDGvahtSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAELRKV--HQYV 259
Cdd:PRK08153 179 AFIEAlpETTLLVLDEAYCETAPAG----AAPPIDTDDPNVIRMRTFSKAYGLAGARVGYAIGAPGTIKAFDKVrnHFGM 254
|
170 180 190
....*....|....*....|....*....|....*
gi 489210460 260 NFCGVTPLQWALADymaghPEHLRQLPGFYQAKRD 294
Cdd:PRK08153 255 NRIAQAAALAALKD-----QAYLAEVVGKIAAARD 284
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
68-188 |
1.12e-05 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 47.05 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 68 EQVAKKIEQFYGrrVSADSEVTITPGATEAI----FSAIQALVHPGDEVVVLDPSYDS----YEPSVQLAGGRCVHVPLV 139
Cdd:PLN02855 79 ELARKKVAAFIN--ASTSREIVFTRNATEAInlvaYTWGLANLKPGDEVILSVAEHHSnivpWQLVAQKTGAVLKFVGLT 156
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 489210460 140 lPDFSIDWQRMAEAIGPRTRLVIIntpHNPSGALISREELDRLAALIRD 188
Cdd:PLN02855 157 -PDEVLDVEQLKELLSEKTKLVAT---HHVSNVLGSILPVEDIVHWAHA 201
|
|
| PRK09331 |
PRK09331 |
Sep-tRNA:Cys-tRNA synthetase; Provisional |
87-154 |
2.21e-05 |
|
Sep-tRNA:Cys-tRNA synthetase; Provisional
Pssm-ID: 236469 Cd Length: 387 Bit Score: 46.08 E-value: 2.21e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489210460 87 EVTITPGATEAIFSAIQALVHPGDeVVVLD--PSYDSYePSVQLAGGRCVHVPLVL-PDFSIDWQRMAEAI 154
Cdd:PRK09331 80 EARVTHGAREGKFAVMHSLCKKGD-YVVLDglAHYTSY-VAAERAGLNVREVPKTGyPEYKITPEAYAEKI 148
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
57-211 |
4.35e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 45.33 E-value: 4.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 57 YAPMTGLPALREQVAKKIEQ----FYGRRVSADsevTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLA-GG 131
Cdd:PRK08637 40 YAPPQGIPELRDLWQEKMLRenpsLSGKKMSLP---IVTNALTHGLSLVADLFVDQGDTVLLPDHNWGNYKLTFNTRrGA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 132 RCVHVPLVLPDFSIDWQRMAEAIGPRTR----LVIINTPHNPSGALISREELDRLAALIRD-----RDIYLISDEVYEHL 202
Cdd:PRK08637 117 EIVTYPIFDEDGGFDTDALKEALQAAYNkgkvIVILNFPNNPTGYTPTEKEATAIVEAIKEladagTKVVAVVDDAYFGL 196
|
....*....
gi 489210460 203 VFDGVAHTS 211
Cdd:PRK08637 197 FYEDSYKES 205
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
91-196 |
1.32e-04 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 43.68 E-value: 1.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 91 TPGATEAIFSAIQAL-VHPGDEVVVldPSYD---SYEPsVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRLVIintP 166
Cdd:cd00616 39 VSSGTAALHLALRALgIGPGDEVIV--PSFTfvaTANA-ILLLGATPVFVDIDPDTYNIDPELIEAAITPRTKAII---P 112
|
90 100 110
....*....|....*....|....*....|....
gi 489210460 167 -H---NPSgalisreELDRLAALIRDRDIYLISD 196
Cdd:cd00616 113 vHlygNPA-------DMDAIMAIAKRHGLPVIED 139
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
94-196 |
1.83e-04 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 43.04 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 94 ATEAIFSAIQAL-VHPGDEVVVLDPSYDSYEPSVQLAGGRCVHVPLVLPDFSIDWQRMAEAIGPRTRLVI-INTPHNPSg 171
Cdd:pfam01041 48 GTAALHLALRALgVGPGDEVITPSFTFVATANAALRLGAKPVFVDIDPDTYNIDPEAIEAAITPRTKAIIpVHLYGQPA- 126
|
90 100
....*....|....*....|....*
gi 489210460 172 alisreELDRLAALIRDRDIYLISD 196
Cdd:pfam01041 127 ------DMDAIRAIAARHGLPVIED 145
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
95-163 |
2.19e-04 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 43.17 E-value: 2.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 95 TEAIFSAIQALVHPGDEVVVL--DPsYDSYEPSVQLAGG----------RCVHVPLvLPDFSIDWQRMAEAIGPRTRLVI 162
Cdd:COG4100 85 THAIALALFGVLRPGDELLSItgKP-YDTLEEVIGIRGEgqgslkefgiSYRQVPL-TEDGKIDLEAIKKAINEKTKMVL 162
|
.
gi 489210460 163 I 163
Cdd:COG4100 163 I 163
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
67-164 |
3.24e-04 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 42.45 E-value: 3.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 67 REQVAkkieQFYGrrVSADSEVTITPGATEAIFSAIQAL---VHPGDEVVVldpsyDSYE------PSVQLA---GGRCV 134
Cdd:cd06453 49 REKVA----RFIN--APSPDEIIFTRNTTEAINLVAYGLgraNKPGDEIVT-----SVMEhhsnivPWQQLAertGAKLK 117
|
90 100 110
....*....|....*....|....*....|
gi 489210460 135 HVPlVLPDFSIDWQRMAEAIGPRTRLVIIN 164
Cdd:cd06453 118 VVP-VDDDGQLDLEALEKLLTERTKLVAVT 146
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
27-169 |
6.33e-04 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 41.55 E-value: 6.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 27 INLSQGFPDFDG--PPELREAVGRHIAAGHNQYAPMT--GLPAlREqvakKIEQFYGRRVSADSEVTITPGAteAIFSAI 102
Cdd:PLN02509 92 VNLDNKFDPFDAmsTPLYQTATFKQPSAIENGPYDYTrsGNPT-RD----ALESLLAKLDKADRAFCFTSGM--AALSAV 164
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489210460 103 QALVHPGDEVVVLDPSYdsyepsvqlaGGRCVHVPLVLPDFSIDWQRM--------AEAIGPRTRLVIINTPHNP 169
Cdd:PLN02509 165 THLIKNGEEIVAGDDVY----------GGSDRLLSQVVPRSGVVVKRVnttnldevAAAIGPQTKLVWLESPTNP 229
|
|
| SepCysS |
cd06452 |
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent ... |
85-174 |
1.04e-03 |
|
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Cys-tRNA(Cys) is produced by O-phosphoseryl-tRNA synthetase which ligates O-phosphoserine (Sep) to tRNA(Cys), and Sep-tRNA:Cys-tRNA synthase (SepCysS) converts Sep-tRNA(Cys) to Cys-tRNA(Cys), in methanogenic archaea. SepCysS forms a dimer, each monomer is composed of a large and small domain; the larger, a typical pyridoxal 5'-phosphate (PLP)-dependent-like enzyme fold. In the active site of each monomer, PLP is covalently bound to a conserved Lys residue near the dimer interface.
Pssm-ID: 99745 Cd Length: 361 Bit Score: 40.84 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 85 DSEVTITPGATEAIFSAIQALVHPGDeVVVLD--PSYDSYePSVQLAGGRCVHVPLV-LPDFSIDWQRMAEAIgprtRLV 161
Cdd:cd06452 59 MDEARVTPGAREGKFAVMHSLCEKGD-WVVVDglAHYTSY-VAAERAGLNVREVPNTgHPEYHITPEGYAEVI----EEV 132
|
90
....*....|...
gi 489210460 162 IINTPHNPSGALI 174
Cdd:cd06452 133 KDEFGKPPALALL 145
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
94-196 |
4.71e-03 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 38.51 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 94 ATEAIFSAIQAL-VHPGDEVVVldPSYD---SYEPsVQLAGGRCVHVPlVLPD-FSIDWQRMAEAIGPRTRLVIIntPH- 167
Cdd:COG0399 54 GTAALHLALRALgIGPGDEVIT--PAFTfvaTANA-ILYVGATPVFVD-IDPDtYNIDPEALEAAITPRTKAIIP--VHl 127
|
90 100 110
....*....|....*....|....*....|.
gi 489210460 168 --NPSgalisreELDRLAALIRDRDIYLISD 196
Cdd:COG0399 128 ygQPA-------DMDAIMAIAKKHGLKVIED 151
|
|
| TA_like |
cd06502 |
Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP) ... |
73-193 |
5.28e-03 |
|
Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a secondary glycine biosynthetic pathway.
Pssm-ID: 99748 [Multi-domain] Cd Length: 338 Bit Score: 38.47 E-value: 5.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489210460 73 KIEQfYGRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDS-YEpsvqlAGGRCVH-----VPLVLPDFSID 146
Cdd:cd06502 36 KLEA-RAAELFGKEAALFVPSGTAANQLALAAHTQPGGSVICHETAHIYtDE-----AGAPEFLsgvklLPVPGENGKLT 109
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 489210460 147 WQRMAEAI-------GPRTRLVIINTPHNpSGALISREELDRLAALIRDRDIYL 193
Cdd:cd06502 110 PEDLEAAIrprddihFPPPSLVSLENTTE-GGTVYPLDELKAISALAKENGLPL 162
|
|
| |
