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Conserved domains on  [gi|489307519|ref|WP_003214954|]
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MULTISPECIES: aspartate/glutamate racemase family protein [Pseudomonas]

Protein Classification

aspartate/glutamate racemase family protein( domain architecture ID 10008322)

aspartate/glutamate racemase family protein similar to Agrobacterium fabrum hydantoin racemase, a key enzyme for the production of optically pure D- and L-amino acids, valuable intermediates for the synthesis of antibiotics, sweeteners, pesticides, pharmaceuticals and biologically active peptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
1-236 1.36e-93

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


:

Pssm-ID: 443302  Cd Length: 237  Bit Score: 274.40  E-value: 1.36e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519   1 MRILVVNVNTTESITEAIAKQARAVASPGTEIVGLTPFFGAESVEGNFESYLAAIAVMDRVM-AYDQPFDAVIQAGYGEH 79
Cdd:COG4126    2 MRILVINPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAArAEAEGADAVVIACFGDP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519  80 GREGLQELLNVPVVDITEAAASTAMFLGHAYSVVTTLDRTVPLIEDRLKLAGLYQRCASVRASGMAVLELEEDPLRAMEA 159
Cdd:COG4126   82 GLEAARELVDIPVVGIAEAAMHAAALLGRRFSVVTTLPRTVPRIEELVRRYGLADRCAGVRALDGPVLELEGDPERALAR 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489307519 160 IVRQAELAISEDKAEVICLGCGGMAGLDEQIRYRTGVPVVDGVTSAVTIAEGLVRLGLSTSKiRTYATPRPKKVIGW 236
Cdd:COG4126  162 LAEAAREAVEEDGADVIVLGCAGMAGLAAALQARLGVPVIDGVAAAVKLAEALVRLGLSTSK-VAYAKPPPKALTGL 237
 
Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
1-236 1.36e-93

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


Pssm-ID: 443302  Cd Length: 237  Bit Score: 274.40  E-value: 1.36e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519   1 MRILVVNVNTTESITEAIAKQARAVASPGTEIVGLTPFFGAESVEGNFESYLAAIAVMDRVM-AYDQPFDAVIQAGYGEH 79
Cdd:COG4126    2 MRILVINPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAArAEAEGADAVVIACFGDP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519  80 GREGLQELLNVPVVDITEAAASTAMFLGHAYSVVTTLDRTVPLIEDRLKLAGLYQRCASVRASGMAVLELEEDPLRAMEA 159
Cdd:COG4126   82 GLEAARELVDIPVVGIAEAAMHAAALLGRRFSVVTTLPRTVPRIEELVRRYGLADRCAGVRALDGPVLELEGDPERALAR 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489307519 160 IVRQAELAISEDKAEVICLGCGGMAGLDEQIRYRTGVPVVDGVTSAVTIAEGLVRLGLSTSKiRTYATPRPKKVIGW 236
Cdd:COG4126  162 LAEAAREAVEEDGADVIVLGCAGMAGLAAALQARLGVPVIDGVAAAVKLAEALVRLGLSTSK-VAYAKPPPKALTGL 237
Asp_Glu_race pfam01177
Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2. ...
 3-209 2.81e-48

Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.


Pssm-ID: 426101  Cd Length: 210  Bit Score: 158.20  E-value: 2.81e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519    3 ILVVNVNTTESITEAIAKQARAVASPGTEIVGLTPFFGAESVEGNFESYLAAIAVMDRV-MAYDQPFDAVIQAGYGEH-G 80
Cdd:pfam01177   1 IGGINPNSTASMTRKIVEAARAVLPPHVPVILVTSPDGPDRIESPEDGALAAPALLEALrRLEAAGADAIVIACFTDHpG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519   81 REGLQELLNVPVVDITEAAASTAMFLGHAYSVVTTLDRTVPLIEDRLKLAGLYQRCASVRAS-GMAVLELEEDPLRAMEA 159
Cdd:pfam01177  81 LDALRELTDIPVLGIAEAAALAALALGGRFGVLTTLGTSSPVYERALRAYGLEVRCPGVRAQeGLPVLIVKGGDTEEARA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 489307519  160 IVRQAELAISEDKAEVICLGCGGMAGLDEQIRYRTGVPVVDGVTSAVTIA 209
Cdd:pfam01177 161 LLLEAAKALVEDGADAIILGCTGLPGLAEELEAELGVPVIDPVDAAVRAA 210
 
Name Accession Description Interval E-value
Dcg1 COG4126
Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];
1-236 1.36e-93

Asp/Glu/hydantoin racemase [Amino acid transport and metabolism];


Pssm-ID: 443302  Cd Length: 237  Bit Score: 274.40  E-value: 1.36e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519   1 MRILVVNVNTTESITEAIAKQARAVASPGTEIVGLTPFFGAESVEGNFESYLAAIAVMDRVM-AYDQPFDAVIQAGYGEH 79
Cdd:COG4126    2 MRILVINPNTSAAMTERIAAAARAVAAPGTEIEAVTAAFGPASIESRYDEALAAPGVLEAAArAEAEGADAVVIACFGDP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519  80 GREGLQELLNVPVVDITEAAASTAMFLGHAYSVVTTLDRTVPLIEDRLKLAGLYQRCASVRASGMAVLELEEDPLRAMEA 159
Cdd:COG4126   82 GLEAARELVDIPVVGIAEAAMHAAALLGRRFSVVTTLPRTVPRIEELVRRYGLADRCAGVRALDGPVLELEGDPERALAR 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489307519 160 IVRQAELAISEDKAEVICLGCGGMAGLDEQIRYRTGVPVVDGVTSAVTIAEGLVRLGLSTSKiRTYATPRPKKVIGW 236
Cdd:COG4126  162 LAEAAREAVEEDGADVIVLGCAGMAGLAAALQARLGVPVIDGVAAAVKLAEALVRLGLSTSK-VAYAKPPPKALTGL 237
Asp_Glu_race pfam01177
Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2. ...
 3-209 2.81e-48

Asp/Glu/Hydantoin racemase; This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.


Pssm-ID: 426101  Cd Length: 210  Bit Score: 158.20  E-value: 2.81e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519    3 ILVVNVNTTESITEAIAKQARAVASPGTEIVGLTPFFGAESVEGNFESYLAAIAVMDRV-MAYDQPFDAVIQAGYGEH-G 80
Cdd:pfam01177   1 IGGINPNSTASMTRKIVEAARAVLPPHVPVILVTSPDGPDRIESPEDGALAAPALLEALrRLEAAGADAIVIACFTDHpG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489307519   81 REGLQELLNVPVVDITEAAASTAMFLGHAYSVVTTLDRTVPLIEDRLKLAGLYQRCASVRAS-GMAVLELEEDPLRAMEA 159
Cdd:pfam01177  81 LDALRELTDIPVLGIAEAAALAALALGGRFGVLTTLGTSSPVYERALRAYGLEVRCPGVRAQeGLPVLIVKGGDTEEARA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 489307519  160 IVRQAELAISEDKAEVICLGCGGMAGLDEQIRYRTGVPVVDGVTSAVTIA 209
Cdd:pfam01177 161 LLLEAAKALVEDGADAIILGCTGLPGLAEELEAELGVPVIDPVDAAVRAA 210
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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