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Conserved domains on  [gi|489440825|ref|WP_003346299|]
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MULTISPECIES: NAD(P)/FAD-dependent oxidoreductase [Pseudomonas syringae group]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11428914)

NAD(P)/FAD-dependent oxidoreductase similar to digeranylgeranylglycerophospholipid reductase, menaquinone reductase, tryptophan 2-halogenase, and protein FixC

CATH:  3.50.50.60|3.40.50.720|3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0071949|GO:0016491
PubMed:  30945211
SCOP:  3000055

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
16-338 2.17e-60

Dehydrogenase (flavoprotein) [Energy production and conversion];


:

Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 197.50  E-value: 2.17e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  16 AGPAGSIAAALLKRQGHDVLIIERQLFPRFSI-GESLLCHCLDFVEEAGMLEAVQaagfQPKNGAAFargeqYSDFDFSD 94
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLE----RPVRGARF-----YSPGGKSV 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  95 TFSNGKPTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVKREDgseySVQASFVLDASGYGRVLPRL 174
Cdd:COG0644   72 ELPPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDDGRVVVRTGDGE----EIRADYVVDADGARSLLARK 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 175 LDLAAPSGFP--VRQAVFTHIEdRIESPPFDRRKILVSIHPQHSDVWFWSIPFSEGRCSIGVvasaerfkdkpedldacl 252
Cdd:COG0644  148 LGLKRRSDEPqdYALAIKEHWE-LPPLEGVDPGAVEFFFGEGAPGGYGWVFPLGDGRVSVGI------------------ 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 253 rafidetpqlasvlknavwdtparTIGGYsanVKTLHGKGFALLGNAAEFLDPVFSSGVTIAMRSASMAAGVLSRQLQGE 332
Cdd:COG0644  209 ------------------------PLGGP---RPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGG 261


                 ....*.
gi 489440825 333 NVDWES 338
Cdd:COG0644  262 DFSAEA 267
 
Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
16-338 2.17e-60

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 197.50  E-value: 2.17e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  16 AGPAGSIAAALLKRQGHDVLIIERQLFPRFSI-GESLLCHCLDFVEEAGMLEAVQaagfQPKNGAAFargeqYSDFDFSD 94
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLE----RPVRGARF-----YSPGGKSV 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  95 TFSNGKPTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVKREDgseySVQASFVLDASGYGRVLPRL 174
Cdd:COG0644   72 ELPPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDDGRVVVRTGDGE----EIRADYVVDADGARSLLARK 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 175 LDLAAPSGFP--VRQAVFTHIEdRIESPPFDRRKILVSIHPQHSDVWFWSIPFSEGRCSIGVvasaerfkdkpedldacl 252
Cdd:COG0644  148 LGLKRRSDEPqdYALAIKEHWE-LPPLEGVDPGAVEFFFGEGAPGGYGWVFPLGDGRVSVGI------------------ 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 253 rafidetpqlasvlknavwdtparTIGGYsanVKTLHGKGFALLGNAAEFLDPVFSSGVTIAMRSASMAAGVLSRQLQGE 332
Cdd:COG0644  209 ------------------------PLGGP---RPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGG 261


                 ....*.
gi 489440825 333 NVDWES 338
Cdd:COG0644  262 DFSAEA 267
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 11-325 1.25e-31

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 122.04  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPRFSIgesllchCLDFVEEAGMLEAVQ--AAGFQPKNGAAFARGEQYS 88
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKP-------CGGALSPRALEELDLpgELIVNLVRGARFFSPNGDS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   89 DFDFSDTFSngkptTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVkreDGSEYSVQASFVLDASGYG 168
Cdd:TIGR02032  76 VEIPIETEL-----AYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRVVVIV---RGSEGTVTAKIVIGADGSR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  169 RVLPRLLdlaapsGFPVRQAVFTHiEDRIESPPFDrrkilVSIHPQHSDVWF----------WSIPFSEGRCSIGV-VAS 237
Cdd:TIGR02032 148 SIVAKKL------GLKKEPREYGV-AARAEVEMPD-----EEVDEDFVEVYIdrgivpggygWVFPKGDGTANVGVgSRS 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  238 AERFKDKPEDLDACLRAFIDEtpQLASVLKNAVWDTPartIGGYSANvktLHGKGFALLGNAAEFLDPVFSSGVTIAMRS 317
Cdd:TIGR02032 216 AEEGEDPKKYLKDFLARRPEL--KDAETVEVCGALIP---IGRPDEK---LVRGNVLLVGDAAGHVNPLTGEGIYYAMRS 287


                  ....*...
gi 489440825  318 ASMAAGVL 325
Cdd:TIGR02032 288 GDIAAEVV 295
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 10-336 4.35e-16

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 78.91  E-value: 4.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   10 QVVVIGAGPAGSIAAALLKRQGHDVLIIERQ----LFPRFSIgesLLCHCLDFVEEAGMLEAVQAAGFQPKNGAAFARGE 85
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVERHattsVLPRAHG---LNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   86 Q---YSDFDFSDTFSNGKPTTfqvqrsEFDKLLADQAALQGVDIRYQEEIVS--ADFDGPQPVLRVkREDGSEYSVQASF 160
Cdd:pfam01494  80 RrraDLDFLTSPPRVTVYPQT------ELEPILVEHAEARGAQVRFGTEVLSleQDGDGVTAVVRD-RRDGEEYTVRAKY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  161 VLDASGYGRVLPRLLDLAAPSGFPVRQAVF-THIEDRIESPPFDRRKILVSIHPQHSDVwFWSIPFSEG--RCSIGVVAS 237
Cdd:pfam01494 153 LVGCDGGRSPVRKTLGIEFEGFEGVPFGSLdVLFDAPDLSDPVERAFVHYLIYAPHSRG-FMVGPWRSAgrERYYVQVPW 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  238 AERFKDKPEDLD-----ACLRAFIDETPQLASVLKNAVWDTPARTIGGYSanvktlHGKGFaLLGNAAEFLDPVFSSGVT 312
Cdd:pfam01494 232 DEEVEERPEEFTdeelkQRLRSIVGIDLALVEILWKSIWGVASRVATRYR------KGRVF-LAGDAAHIHPPTGGQGLN 304

                         330       340
                  ....*....|....*....|....
gi 489440825  313 IAMRSASMAAGVLSRQLQGENVDW 336
Cdd:pfam01494 305 TAIQDAFNLAWKLAAVLRGQAGES 328
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-166 1.10e-09

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 59.92  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   4 TDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQL----FPR-FSI-GEsllchCLDFVEEAGMLEAVQAAGFqPKN 77
Cdd:PRK06183   6 PDAHDTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPtlydLPRaVGIdDE-----ALRVLQAIGLADEVLPHTT-PNH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  78 GAAF--ARGEQYSDFDFSDTFSNGKPTTFQVQRSEFDKLLADQAA-LQGVDIRYQEEIVSADFDGPQPVLRVKREDGSEY 154
Cdd:PRK06183  80 GMRFldAKGRCLAEIARPSTGEFGWPRRNAFHQPLLEAVLRAGLArFPHVRVRFGHEVTALTQDDDGVTVTLTDADGQRE 159

                        170
                 ....*....|..
gi 489440825 155 SVQASFVLDASG 166
Cdd:PRK06183 160 TVRARYVVGCDG 171
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 11-41 7.84e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 36.72  E-value: 7.84e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 489440825    11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQL 41
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLDVRP 53
 
Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
16-338 2.17e-60

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 197.50  E-value: 2.17e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  16 AGPAGSIAAALLKRQGHDVLIIERQLFPRFSI-GESLLCHCLDFVEEAGMLEAVQaagfQPKNGAAFargeqYSDFDFSD 94
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLE----RPVRGARF-----YSPGGKSV 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  95 TFSNGKPTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVKREDgseySVQASFVLDASGYGRVLPRL 174
Cdd:COG0644   72 ELPPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDDGRVVVRTGDGE----EIRADYVVDADGARSLLARK 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 175 LDLAAPSGFP--VRQAVFTHIEdRIESPPFDRRKILVSIHPQHSDVWFWSIPFSEGRCSIGVvasaerfkdkpedldacl 252
Cdd:COG0644  148 LGLKRRSDEPqdYALAIKEHWE-LPPLEGVDPGAVEFFFGEGAPGGYGWVFPLGDGRVSVGI------------------ 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 253 rafidetpqlasvlknavwdtparTIGGYsanVKTLHGKGFALLGNAAEFLDPVFSSGVTIAMRSASMAAGVLSRQLQGE 332
Cdd:COG0644  209 ------------------------PLGGP---RPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGG 261


                 ....*.
gi 489440825 333 NVDWES 338
Cdd:COG0644  262 DFSAEA 267
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 11-325 1.25e-31

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 122.04  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPRFSIgesllchCLDFVEEAGMLEAVQ--AAGFQPKNGAAFARGEQYS 88
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKP-------CGGALSPRALEELDLpgELIVNLVRGARFFSPNGDS 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   89 DFDFSDTFSngkptTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVkreDGSEYSVQASFVLDASGYG 168
Cdd:TIGR02032  76 VEIPIETEL-----AYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRVVVIV---RGSEGTVTAKIVIGADGSR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  169 RVLPRLLdlaapsGFPVRQAVFTHiEDRIESPPFDrrkilVSIHPQHSDVWF----------WSIPFSEGRCSIGV-VAS 237
Cdd:TIGR02032 148 SIVAKKL------GLKKEPREYGV-AARAEVEMPD-----EEVDEDFVEVYIdrgivpggygWVFPKGDGTANVGVgSRS 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  238 AERFKDKPEDLDACLRAFIDEtpQLASVLKNAVWDTPartIGGYSANvktLHGKGFALLGNAAEFLDPVFSSGVTIAMRS 317
Cdd:TIGR02032 216 AEEGEDPKKYLKDFLARRPEL--KDAETVEVCGALIP---IGRPDEK---LVRGNVLLVGDAAGHVNPLTGEGIYYAMRS 287


                  ....*...
gi 489440825  318 ASMAAGVL 325
Cdd:TIGR02032 288 GDIAAEVV 295
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 9-335 1.84e-23

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 100.01  E-value: 1.84e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPRFSI-GESLLCHCLDFVEEAGMLEAVQAAGFQPKNGAAF--ARGE 85
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGrGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRdgSDGR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  86 QYSDFDFSDTfsnGKPTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVkrEDGSEysVQASFVLDAS 165
Cdd:COG0654   84 VLARFDAAET---GLPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADGVTVTL--ADGRT--LRADLVVGAD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 166 GygrvlprlldlaapSGFPVRQAVFTHIEDRiesppfdrrkilvsihpQHSDVWFWsipfsegrcsIGVVAsaerfkdkp 245
Cdd:COG0654  157 G--------------ARSAVRRLLGIGFTGR-----------------DYPQRALW----------AGVRT--------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 246 eDLDACLRAFIDETPQLASVLKNAVWDTPARTiggysanVKTLHGKGFALLGNAAEFLDPVFSSGVTIAMRSASMAAGVL 325
Cdd:COG0654  187 -ELRARLAAAGPRLGELLELSPRSAFPLRRRR-------AERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKL 258

                        330
                 ....*....|
gi 489440825 326 SRQLQGENVD 335
Cdd:COG0654  259 AAALRGRDDE 268
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 10-336 4.35e-16

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 78.91  E-value: 4.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   10 QVVVIGAGPAGSIAAALLKRQGHDVLIIERQ----LFPRFSIgesLLCHCLDFVEEAGMLEAVQAAGFQPKNGAAFARGE 85
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVERHattsVLPRAHG---LNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   86 Q---YSDFDFSDTFSNGKPTTfqvqrsEFDKLLADQAALQGVDIRYQEEIVS--ADFDGPQPVLRVkREDGSEYSVQASF 160
Cdd:pfam01494  80 RrraDLDFLTSPPRVTVYPQT------ELEPILVEHAEARGAQVRFGTEVLSleQDGDGVTAVVRD-RRDGEEYTVRAKY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  161 VLDASGYGRVLPRLLDLAAPSGFPVRQAVF-THIEDRIESPPFDRRKILVSIHPQHSDVwFWSIPFSEG--RCSIGVVAS 237
Cdd:pfam01494 153 LVGCDGGRSPVRKTLGIEFEGFEGVPFGSLdVLFDAPDLSDPVERAFVHYLIYAPHSRG-FMVGPWRSAgrERYYVQVPW 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  238 AERFKDKPEDLD-----ACLRAFIDETPQLASVLKNAVWDTPARTIGGYSanvktlHGKGFaLLGNAAEFLDPVFSSGVT 312
Cdd:pfam01494 232 DEEVEERPEEFTdeelkQRLRSIVGIDLALVEILWKSIWGVASRVATRYR------KGRVF-LAGDAAHIHPPTGGQGLN 304

                         330       340
                  ....*....|....*....|....
gi 489440825  313 IAMRSASMAAGVLSRQLQGENVDW 336
Cdd:pfam01494 305 TAIQDAFNLAWKLAAVLRGQAGES 328
Trp_halogenase pfam04820
Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form ...
 11-319 6.70e-16

Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form 7-chlorotryptophan. This is the first step in the biosynthesis of pyrrolnitrin, an antibiotic with broad-spectrum anti-fungal activity. Tryptophan halogenase is NADH-dependent.


Pssm-ID: 398475 [Multi-domain]  Cd Length: 457  Bit Score: 79.30  E-value: 6.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   11 VVVIGAGPAGSIAAALLKRQ---GHDVLIIERQLFPRFSIGESLLCHCLDFVEEAGMLEA--VQAAGFQPKNGAAF---- 81
Cdd:pfam04820   2 IVIVGGGTAGWMAAAALARAlkgGLDVTLVESEEIGTVGVGEATIPSIRTFNRMLGIDEAefLRATQATFKLGIRFedwg 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   82 ARGEQY-----------------------------SDFD-------------FSDTFSNGKPTT------FQVQRSEFDK 113
Cdd:pfam04820  82 RRGERYihpfgvtghpidgvpfhhywlrlrargfaGPLDdyclpavaalagkFSPPPKDPRSGLsglsyaYHFDAALYAR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  114 LLADQAALQGVDIRyQEEIVSADFDGPQPVLRVKREDGSEYSvqASFVLDASGYGRvlpRLLDLAAPSGF-------PVR 186
Cdd:pfam04820 162 FLRRNAEARGVTRV-EGKVVDVQLDADGFVTSLRLEDGREVE--ADLFIDCSGFRG---LLIEQALKTGYedwsdwlPCD 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  187 QAVFTHIEDRIESPPFDRrkilvSIhpQHSDVWFWSIPFSEGRCSIGVVASAerfkdkPEDLDACLRAFIDETPQLASVL 266
Cdd:pfam04820 236 RALAVQCESVGPPEPYTR-----AT--AHDAGWRWRIPLQHRLGNGYVYSSA------HADDDEALAELLANLGGIPLAE 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 489440825  267 KNAVWDTPARTiggysanvKTLHGKGFALLGNAAEFLDPVFSSGVTIAMRSAS 319
Cdd:pfam04820 303 PRLIRFTTGRR--------KQAWVKNVVALGLASGFLEPLESTSIHLIQSALR 347
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-166 1.10e-09

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 59.92  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   4 TDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQL----FPR-FSI-GEsllchCLDFVEEAGMLEAVQAAGFqPKN 77
Cdd:PRK06183   6 PDAHDTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPtlydLPRaVGIdDE-----ALRVLQAIGLADEVLPHTT-PNH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  78 GAAF--ARGEQYSDFDFSDTFSNGKPTTFQVQRSEFDKLLADQAA-LQGVDIRYQEEIVSADFDGPQPVLRVKREDGSEY 154
Cdd:PRK06183  80 GMRFldAKGRCLAEIARPSTGEFGWPRRNAFHQPLLEAVLRAGLArFPHVRVRFGHEVTALTQDDDGVTVTLTDADGQRE 159

                        170
                 ....*....|..
gi 489440825 155 SVQASFVLDASG 166
Cdd:PRK06183 160 TVRARYVVGCDG 171
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 10-167 6.69e-08

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 54.03  E-value: 6.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  10 QVVVIGAGPAGSIAAALLKRQGHDVLIIERQlfPRfsigesllchclDFVEE---AGMLEAV-----QAAGF-------- 73
Cdd:PRK08243   4 QVAIIGAGPAGLLLGQLLHLAGIDSVVLERR--SR------------EYVEGrirAGVLEQGtvdllREAGVgermdreg 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  74 QPKNGAAFARGEQYSDFDFSDtFSNGKPTTFQVQrSEFDKLLADQAALQGVDIRYQEEIVS-ADFDGPQPVLRVkREDGS 152
Cdd:PRK08243  70 LVHDGIELRFDGRRHRIDLTE-LTGGRAVTVYGQ-TEVTRDLMAARLAAGGPIRFEASDVAlHDFDSDRPYVTY-EKDGE 146

                        170
                 ....*....|....*
gi 489440825 153 EYSVQASFVLDASGY 167
Cdd:PRK08243 147 EHRLDCDFIAGCDGF 161
PRK08244 PRK08244
monooxygenase;
10-213 8.99e-08

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 53.98  E-value: 8.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  10 QVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFP-RFSIGESLLCHCLDFVEEAGMLEAVQAAGfQPKNGAAFARGEQYS 88
Cdd:PRK08244   4 EVIIIGGGPVGLMLASELALAGVKTCVIERLKETvPYSKALTLHPRTLEILDMRGLLERFLEKG-RKLPSGHFAGLDTRL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  89 DFDFSDTFSNgkpTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVKREDGSEySVQASFVLDASGYG 168
Cdd:PRK08244  83 DFSALDTSSN---YTLFLPQAETEKVLEEHARSLGVEIFRGAEVLAVRQDGDGVEVVVRGPDGLR-TLTSSYVVGADGAG 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489440825 169 RVLPRlldlAAPSGFPVRQAVFTHI--EDRIESPP------FDRRKILVSIHP 213
Cdd:PRK08244 159 SIVRK----QAGIAFPGTDATFTAMlgDVVLKDPPpssvlsLCTREGGVMIVP 207
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 2-124 4.83e-07

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 52.04  E-value: 4.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   2 PITDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIE---------RQLFPRFSIGESLLchcldfveEAGmLEAVQAAG 72
Cdd:PRK12814 187 ERAPKSGKKVAIIGAGPAGLTAAYYLLRKGHDVTIFDaneqaggmmRYGIPRFRLPESVI--------DAD-IAPLRAMG 257

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489440825  73 fqpkngaafargeqySDFDFSDTFsnGKPTTFQVQRSEFDKLL----ADQAALQGV 124
Cdd:PRK12814 258 ---------------AEFRFNTVF--GRDITLEELQKEFDAVLlavgAQKASKMGI 296
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
13-40 6.12e-07

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 46.37  E-value: 6.12e-07
                          10        20
                  ....*....|....*....|....*...
gi 489440825   13 VIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKR 28
PRK07045 PRK07045
putative monooxygenase; Reviewed
 11-332 6.50e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 51.06  E-value: 6.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPRFSIGESLLCHC-LDFVEEAGMLEAVQAAGFQPKNG-AAFARGEQYS 88
Cdd:PRK07045   8 VLINGSGIAGVALAHLLGARGHSVTVVERAARNRAQNGADLLKPSgIGVVRAMGLLDDVFAAGGLRRDAmRLYHDKELIA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  89 DFDFSDTFSNGKPTTF---QVQRsefdKLLADQAALQGVDIRYQEEIVSADFDGPQPVLRVKREDGSeySVQASFVLDAS 165
Cdd:PRK07045  88 SLDYRSASALGYFILIpceQLRR----LLLAKLDGLPNVRLRFETSIERIERDADGTVTSVTLSDGE--RVAPTVLVGAD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 166 GY-GRVLPRLLDLAAPS-GFPVRQAVFThiedrIESPPFDRRKILVSIHPQHSDVWFWSIPFSEGRCSI--------GVV 235
Cdd:PRK07045 162 GArSMIRDDVLRMPAERvPYATPMAFGT-----IALTDSVRECNRLYVDSNQGLAYFYPIGDQATRLVVsfpademqGYL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 236 ASAERfkdkpEDLDACLRAFIDETPQLASVLKNAVWDTPARTIGgySANVKTLHGKGFALLGNAAEFLDPVFSSGVTIAM 315
Cdd:PRK07045 237 ADTTR-----TKLLARLNEFVGDESADAMAAIGAGTAFPLIPLG--RMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAI 309

                        330
                 ....*....|....*..
gi 489440825 316 RSASMAAGVLSRQLQGE 332
Cdd:PRK07045 310 EDAGELGACLDLHLSGQ 326
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 11-259 1.01e-06

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 50.64  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQlfPRFSIGESLLC---HCLDFVEEAGMLEAVQAAGFQPKNGAAFARGEQY 87
Cdd:PRK08132  26 VVVVGAGPVGLALAIDLAQQGVPVVLLDDD--DTLSTGSRAICfakRSLEIFDRLGCGERMVDKGVSWNVGKVFLRDEEV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  88 SDFDFSDTFSNGKPTTFQVQRSEFDKLLADQA-ALQGVDIRYQEEIVSADFDGPQPVLRVKREDGSeYSVQASFV----- 161
Cdd:PRK08132 104 YRFDLLPEPGHRRPAFINLQQYYVEGYLVERAqALPNIDLRWKNKVTGLEQHDDGVTLTVETPDGP-YTLEADWViacdg 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 162 ----------LDASGY---GRVLprLLDLAAPSGFPV-RQAVFThiedriesPPFDR-RKILVsiHPQHSDVwfWSIPFs 226
Cdd:PRK08132 183 arsplremlgLEFEGRtfeDRFL--IADVKMKADFPTeRWFWFD--------PPFHPgQSVLL--HRQPDNV--WRIDF- 247

                        250       260       270
                 ....*....|....*....|....*....|...
gi 489440825 227 egrcSIGVVASAERFKdKPEDLDACLRAFIDET 259
Cdd:PRK08132 248 ----QLGWDADPEAEK-KPENVIPRVRALLGED 275
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 11-40 2.07e-06

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 49.85  E-value: 2.07e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:COG1233    6 VVVIGAGIGGLAAAALLARAGYRVTVLEKN 35
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 3-46 4.98e-06

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 47.88  E-value: 4.98e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 489440825   3 ITDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIER--QLFPRFS 46
Cdd:COG0446  119 LKEFKGKRAVVIGGGPIGLELAEALRKRGLKVTLVERapRLLGVLD 164
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 11-266 7.27e-06

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 47.78  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFP------------RFSIGESLLCHCLDFVEEA-GMLEAVQA-----AG 72
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDPgsgasgrnagliHPGLRYLEPSELARLALEAlDLWEELEEelgidCG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   73 FQPKNGAAFARGEQYSDFD--FSDTFSNGK--------------------------PTTFQVQRSEFDKLLADQAALQGV 124
Cdd:pfam01266  82 FRRCGVLVLARDEEEEALEklLAALRRLGVpaelldaeelrelepllpglrgglfyPDGGHVDPARLLRALARAAEALGV 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  125 DIRYQEEIVSADFDGPQPVLRVKREdgseysvqASFVLDASGYGRVLPRLLDLAAPsGFPVR-QAVFThiedrieSPPFD 203
Cdd:pfam01266 162 RIIEGTEVTGIEEEGGVWGVVTTGE--------ADAVVNAAGAWADLLALPGLRLP-VRPVRgQVLVL-------EPLPE 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489440825  204 RRKILVSIHPQHSDVWFWSIPFSEGRCSIG---VVASAERFKDKPEDLDACLRAFIDETPQLASVL 266
Cdd:pfam01266 226 ALLILPVPITVDPGRGVYLRPRADGRLLLGgtdEEDGFDDPTPDPEEIEELLEAARRLFPALADIE 291
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 11-186 1.15e-05

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 47.22  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFprfsIGesllchcldfveeaGML--EAVQA-AGFQPKNGAA------- 80
Cdd:pfam12831   2 VVVVGGGPAGVAAAIAAARAGAKVLLVERRGF----LG--------------GMLtsGLVGPdMGFYLNKEQVvggiare 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   81 -FARGEQYSDFDFSDtfsnGKPTTFQVQRSEFDKLLADQAALQ-GVDIRYQEEIVSADFDGPQpVLRVK-REDGSEYSVQ 157
Cdd:pfam12831  64 fRQRLRARGGLPGPY----GLRGGWVPFDPEVAKAVLDEMLAEaGVTVLLHTRVVGVVKEGGR-ITGVTvETKGGRITIR 138

                         170       180
                  ....*....|....*....|....*....
gi 489440825  158 ASFVLDASGYGrvlprllDLAAPSGFPVR 186
Cdd:pfam12831 139 AKVFIDATGDG-------DLAALAGAPYR 160
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
11-38 1.30e-05

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 47.22  E-value: 1.30e-05
                         10        20
                 ....*....|....*....|....*...
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIE 38
Cdd:COG1231   10 VVIVGAGLAGLAAARELRKAGLDVTVLE 37
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
12-39 1.84e-05

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 46.58  E-value: 1.84e-05
                         10        20
                 ....*....|....*....|....*...
gi 489440825  12 VVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEK 28
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 4-187 2.73e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 46.01  E-value: 2.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   4 TDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIERqlfpRFSIG--------ESLLC----HCLDFveeagmleavqaA 71
Cdd:COG2072    2 AATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEK----ADDVGgtwrdnryPGLRLdtpsHLYSL------------P 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  72 GFQ-PKNGAAFARGEQYSDFdFSDTfsngkpttfqvqrsefdkllADQAALQGvDIRYQEEIVSADFDGPQPVLRVKRED 150
Cdd:COG2072   66 FFPnWSDDPDFPTGDEILAY-LEAY--------------------ADKFGLRR-PIRFGTEVTSARWDEADGRWTVTTDD 123

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 489440825 151 GSEYSvqASFVLDASGYGRVlPRLLDLAAPSGFPVRQ 187
Cdd:COG2072  124 GETLT--ARFVVVATGPLSR-PKIPDIPGLEDFAGEQ 157
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
11-40 4.93e-05

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 45.28  E-value: 4.93e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:COG0665    5 VVVIGGGIAGLSTAYHLARRGLDVTVLERG 34
PRK07208 PRK07208
hypothetical protein; Provisional
 9-39 6.10e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 44.88  E-value: 6.10e-05
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:PRK07208   5 KSVVIIGAGPAGLTAAYELLKRGYPVTVLEA 35
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 7-123 6.19e-05

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 44.90  E-value: 6.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   7 EIRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFP--RFSIGESLLCHCL-----DFVEEAGMLEAV--QAAGFQPKN 77
Cdd:PRK10157   4 DIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAgaKNVTGGRLYAHSLehiipGFADSAPVERLIthEKLAFMTEK 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 489440825  78 GAA---FARGEQysdfdfsdtfSNGKPTTFQVQRSEFDKLLADQAALQG 123
Cdd:PRK10157  84 SAMtmdYCNGDE----------TSPSQRSYSVLRSKFDAWLMEQAEEAG 122
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 11-39 8.37e-05

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 44.40  E-value: 8.37e-05
                         10        20
                 ....*....|....*....|....*....
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:PRK06292   6 VIVIGAGPAGYVAARRAAKLGKKVALIEK 34
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 11-40 8.57e-05

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 44.36  E-value: 8.57e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLARAGHEVTVFEAL 153
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
11-177 1.27e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 43.57  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGsIAAAL-LKRQGHDVLIIErqlfpRFSIGESLLchcldfveEAGMLEavqaagfqpkNGAAFARGEQYSD 89
Cdd:COG0492    3 VVIIGAGPAG-LTAAIyAARAGLKTLVIE-----GGEPGGQLA--------TTKEIE----------NYPGFPEGISGPE 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  90 FdfsdtfsngkpttfqVQRsefdklLADQAALQGVDIRYqEEIVSADFDGpqPVLRVKREDGSEYsvQASFVLDASGYGr 169
Cdd:COG0492   59 L---------------AER------LREQAERFGAEILL-EEVTSVDKDD--GPFRVTTDDGTEY--EAKAVIIATGAG- 111


                 ....*...
gi 489440825 170 vlPRLLDL 177
Cdd:COG0492  112 --PRKLGL 117
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 9-39 1.42e-04

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 44.01  E-value: 1.42e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:PRK11749 141 KKVAVIGAGPAGLTAAHRLARKGYDVTIFEA 171
TIGR00275 TIGR00275
flavoprotein, HI0933 family; The model when searched with a partial length search brings in ...
 12-134 1.63e-04

flavoprotein, HI0933 family; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 272992 [Multi-domain]  Cd Length: 400  Bit Score: 43.74  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   12 VVIGAGPAGSIAAALLKRQGHDVLIIERQLfprfSIGESLL------ChclDFVEEAGMLEAVQaagFQPKNG----AAF 81
Cdd:TIGR00275   1 IIIGGGAAGLMAAITAARAGLSVLLLEKNK----KIGKKLLisgggrC---NLTNSCPTPEFVA---YYPRNGkflrSAL 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489440825   82 ARgeqysdFDFSDTF----SNGKPTT-------FQVQRSEFD--KLLADQAALQGVDIRYQEEIVS 134
Cdd:TIGR00275  71 SR------FSNKDLIdffeSLGLELKveedgrvFPCSDSAADvlDALLNELKELGVEILTNSKVKS 130
PRK06184 PRK06184
hypothetical protein; Provisional
 1-102 1.71e-04

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 43.82  E-value: 1.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   1 MPITDreirqVVVIGAGPAGSIAAALLKRQGHDVLIIER--QLFPRfSIGESLLCHCLDFVEEAGMLEAVQAAGFQPKNG 78
Cdd:PRK06184   1 YTTTD-----VLIVGAGPTGLTLAIELARRGVSFRLIEKapEPFPG-SRGKGIQPRTQEVFDDLGVLDRVVAAGGLYPPM 74

                         90       100
                 ....*....|....*....|....
gi 489440825  79 AAFARGEQYSDfdfSDTFSNGKPT 102
Cdd:PRK06184  75 RIYRDDGSVAE---SDMFAHLEPT 95
HI0933_like pfam03486
HI0933-like protein;
9-39 1.85e-04

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 43.34  E-value: 1.85e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 489440825    9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEK 31
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 10-39 2.06e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 43.08  E-value: 2.06e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 489440825   10 QVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKVTLIED 31
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 11-39 2.17e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 43.28  E-value: 2.17e-04
                         10        20
                 ....*....|....*....|....*....
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:COG1232    4 VAVIGGGIAGLTAAYRLAKAGHEVTVLEA 32
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 9-40 2.47e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 43.33  E-value: 2.47e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:PRK12771 138 KRVAVIGGGPAGLSAAYHLRRMGHAVTIFEAG 169
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 11-42 2.54e-04

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 43.15  E-value: 2.54e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLF 42
Cdd:COG1249    6 LVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL 37
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 9-40 2.96e-04

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 42.93  E-value: 2.96e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:PLN02172  11 QHVAVIGAGAAGLVAARELRREGHTVVVFERE 42
PRK06185 PRK06185
FAD-dependent oxidoreductase;
3-335 3.03e-04

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 42.54  E-value: 3.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   3 ITDREIRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQL-FPRFSIGESLLCHCLDFVEEAGMLEAVQAAGFQP-KNGAA 80
Cdd:PRK06185   1 MAEVETTDCCIVGGGPAGMMLGLLLARAGVDVTVLEKHAdFLRDFRGDTVHPSTLELMDELGLLERFLELPHQKvRTLRF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  81 FARGEQYSDFDFSDTfsngkPTTFQ----VQRSEFDKLLADQA-ALQGVDIRYQEEIVSADFDGPQPV-LRVKREDGsEY 154
Cdd:PRK06185  81 EIGGRTVTLADFSRL-----PTPYPyiamMPQWDFLDFLAEEAsAYPNFTLRMGAEVTGLIEEGGRVTgVRARTPDG-PG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 155 SVQASFVLDASGYGRVLPRLLDLAA---PSGFPV------RQAvfthiEDRIESPP-FDRRKILVSIHpqHSDVWfwsip 224
Cdd:PRK06185 155 EIRADLVVGADGRHSRVRALAGLEVrefGAPMDVlwfrlpREP-----DDPESLMGrFGPGQGLIMID--RGDYW----- 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 225 fsegRCSIgVVASAERFKDKPEDLDAcLRAFIDET-PQLASVLKN-AVWD-------TPARtiggysanVKTLHGKGFAL 295
Cdd:PRK06185 223 ----QCGY-VIPKGGYAALRAAGLEA-FRERVAELaPELADRVAElKSWDdvklldvRVDR--------LRRWHRPGLLC 288

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 489440825 296 LGNAAEFLDPVFSSGVTIAMRSASMAAGVLSRQLQGENVD 335
Cdd:PRK06185 289 IGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGRVS 328
PLN02976 PLN02976
amine oxidase
 5-38 3.79e-04

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 42.93  E-value: 3.79e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 489440825    5 DREIRQ-VVVIGAGPAGSIAAALLKRQGHDVLIIE 38
Cdd:PLN02976  689 DSVDRKkIIVVGAGPAGLTAARHLQRQGFSVTVLE 723
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 11-73 4.15e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 42.53  E-value: 4.15e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLF--PRFSIGESLLCHCLDFVEEAGM---LEAVQAAGF 73
Cdd:PTZ00367  36 VIIVGGSIAGPVLAKALSKQGRKVLMLERDLFskPDRIVGELLQPGGVNALKELGMeecAEGIGMPCF 103
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
11-39 4.94e-04

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 42.02  E-value: 4.94e-04
                         10        20
                 ....*....|....*....|....*....
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:COG2509   33 VVIVGAGPAGLFAALELAEAGLKPLVLER 61
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 11-44 5.72e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 41.74  E-value: 5.72e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPR 44
Cdd:COG1053    6 VVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRG 39
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 9-39 5.76e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 42.07  E-value: 5.76e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:PRK12810 144 KKVAVVGSGPAGLAAADQLARAGHKVTVFER 174
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 9-39 6.45e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 41.21  E-value: 6.45e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:COG0569   96 MHVIIIGAGRVGRSLARELEEEGHDVVVIDK 126
PRK10015 PRK10015
oxidoreductase; Provisional
 12-181 7.79e-04

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 41.50  E-value: 7.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  12 VVIGAGPAGSIAAALLKRQGHDVLIIER--QLFPRFSIGESLLCHCLD-----FVEEAGMLEAVQaagfqpKNGAAFARG 84
Cdd:PRK10015   9 IVVGAGVAGSVAALVMARAGLDVLVIERgdSAGCKNMTGGRLYAHTLEaiipgFAASAPVERKVT------REKISFLTE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  85 EQYSDFDFSDTFSNGKP-TTFQVQRSEFDKLLADQAalqgvdiryqeEIVSADFdgpQPVLRVK---REDGSEYSVQ--- 157
Cdd:PRK10015  83 ESAVTLDFHREQPDVPQhASYTVLRNRLDPWLMEQA-----------EQAGAQF---IPGVRVDalvREGNKVTGVQagd 148

                        170       180
                 ....*....|....*....|....*...
gi 489440825 158 ----ASFVLDASGYGRVLPRLLDLAAPS 181
Cdd:PRK10015 149 dileANVVILADGVNSMLGRSLGMVPAS 176
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 11-39 8.05e-04

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 41.49  E-value: 8.05e-04
                          10        20
                  ....*....|....*....|....*....
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQ 29
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
9-40 9.78e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 41.38  E-value: 9.78e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 489440825   9 RQVVVIGAGPAGsIAAAL-LKRQGHDVLIIERQ 40
Cdd:COG1148  141 KRALVIGGGIAG-MTAALeLAEQGYEVYLVEKE 172
PLN00093 PLN00093
geranylgeranyl diphosphate reductase; Provisional
 2-41 1.01e-03

geranylgeranyl diphosphate reductase; Provisional


Pssm-ID: 177713 [Multi-domain]  Cd Length: 450  Bit Score: 41.28  E-value: 1.01e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 489440825   2 PITDREIRqVVVIGAGPAGSIAAALLKRQGHDVLIIERQL 41
Cdd:PLN00093  34 KLSGRKLR-VAVIGGGPAGACAAETLAKGGIETFLIERKL 72
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 11-39 1.45e-03

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 40.58  E-value: 1.45e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAA-LLKRQGHDVLIIER 39
Cdd:COG2303    7 YVIVGAGSAGCVLANrLSEDAGLRVLLLEA 36
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
6-44 1.76e-03

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 40.12  E-value: 1.76e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 489440825   6 REIRQVVVIGAGPAGSIAAALLKRQGHDVLIIER--QLFPR 44
Cdd:COG1251  140 APGKRVVVIGGGLIGLEAAAALRKRGLEVTVVERapRLLPR 180
GIDA pfam01134
Glucose inhibited division protein A;
11-37 1.79e-03

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 40.23  E-value: 1.79e-03
                          10        20
                  ....*....|....*....|....*..
gi 489440825   11 VVVIGAGPAGSIAAALLKRQGHDVLII 37
Cdd:pfam01134   2 VIVIGGGHAGCEAALAAARMGAKVLLI 28
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
11-40 1.98e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 40.14  E-value: 1.98e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:PRK05249   8 LVVIGSGPAGEGAAMQAAKLGKRVAVIERY 37
PRK06370 PRK06370
FAD-containing oxidoreductase;
12-42 2.01e-03

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 40.19  E-value: 2.01e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825  12 VVIGAGPAGSIAAALLKRQGHDVLIIERQLF 42
Cdd:PRK06370   9 IVIGAGQAGPPLAARAAGLGMKVALIERGLL 39
PRK06753 PRK06753
hypothetical protein; Provisional
 11-40 2.73e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 39.67  E-value: 2.73e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQ 40
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKN 32
PRK06847 PRK06847
hypothetical protein; Provisional
 8-128 3.56e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 39.47  E-value: 3.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   8 IRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPR-FSIGESLLCHCLDFVEEAGMLEAVQAAGFQPKNGAAF-ARGE 85
Cdd:PRK06847   4 VKKVLIVGGGIGGLSAAIALRRAGIAVDLVEIDPEWRvYGAGITLQGNALRALRELGVLDECLEAGFGFDGVDLFdPDGT 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 489440825  86 QYSDFDFSDTFSNGKPTTFQVQRSEFDKLLADQAALQGVDIRY 128
Cdd:PRK06847  84 LLAELPTPRLAGDDLPGGGGIMRPALARILADAARAAGADVRL 126
PRK05868 PRK05868
FAD-binding protein;
8-341 3.93e-03

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 39.20  E-value: 3.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825   8 IRQVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFPRFSiGESLLCH--CLDFVEEAGMLEAVQAAGFQpkngaafARGE 85
Cdd:PRK05868   1 MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPG-GQAIDVRgpALDVLERMGLLAAAQEHKTR-------IRGA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825  86 QYSDFDFSDTF--SNGKPTTFQVQRSEFDKLLADQAALQGVDIRYQEEIVsadFDGPQPVLrvkREDGSeySVQASFVld 163
Cdd:PRK05868  73 SFVDRDGNELFrdTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYL---FDDSISTL---QDDGD--SVRVTFE-- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 164 asgygRVLPRLLDLA-APSGF--PVRQAVFTHIEDRIEsppfdRRKILVSIH--PQHSDVWFWSI--------------- 223
Cdd:PRK05868 143 -----RAAAREFDLViGADGLhsNVRRLVFGPEEQFVK-----RLGTHAAIFtvPNFLELDYWQTwhygdstmagvysar 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489440825 224 PFSEGRCSIGVVASAER--FKDKPEDLDACLRAFIDE---TPQLASVLKNAvwdtPARTIGGYSANVKTLHGKG-FALLG 297
Cdd:PRK05868 213 NNTEARAALAFMDTELRidYRDTEAQFAELQRRMAEDgwvRAQLLHYMRSA----PDFYFDEMSQILMDRWSRGrVALVG 288

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 489440825 298 NAAEFLDPVFSSGVTIAMRSASMAAGvlsrQLQGENVDWESEFA 341
Cdd:PRK05868 289 DAGYCCSPLSGQGTSVALLGAYILAG----ELKAAGDDYQLGFA 328
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
11-41 6.35e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 38.34  E-value: 6.35e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQL 41
Cdd:PRK07494  10 IAVIGGGPAGLAAAIALARAGASVALVAPEP 40
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
11-39 6.37e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 38.59  E-value: 6.37e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 489440825  11 VVVIGAGPAG-SIAAALLKRQGHDVLIIER 39
Cdd:COG0579    7 VVIIGAGIVGlALARELSRYEDLKVLVLEK 36
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 11-41 7.84e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 36.72  E-value: 7.84e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 489440825    11 VVVIGAGPAGSIAAALLKRQGHDVLIIERQL 41
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLDVRP 53
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 9-43 8.90e-03

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 38.08  E-value: 8.90e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 489440825   9 RQVVVIGAGPAGSIAAALLKRQGHDVLIIERQLFP 43
Cdd:PRK12409   2 SHIAVIGAGITGVTTAYALAQRGYQVTVFDRHRYA 36
PRK07233 PRK07233
hypothetical protein; Provisional
 11-39 9.86e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 37.94  E-value: 9.86e-03
                         10        20
                 ....*....|....*....|....*....
gi 489440825  11 VVVIGAGPAGSIAAALLKRQGHDVLIIER 39
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEA 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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