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Conserved domains on  [gi|489458611|ref|WP_003363842|]
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MULTISPECIES: pca regulon transcriptional regulator PcaR [Pseudomonas]

Protein Classification

IclR family transcriptional regulator( domain architecture ID 11494263)

IclR family transcriptional regulator functions as an activator or repressor of genes involved in primary and secondary metabolism, virulence, quorum sensing, and sporulation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
pcaR_pcaU TIGR02431
beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this ...
30-278 9.61e-123

beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions]


:

Pssm-ID: 131484 [Multi-domain]  Cd Length: 248  Bit Score: 350.41  E-value: 9.61e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611   30 DPDFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRTYSLLPKVLTLGHAYLSSTPL 109
Cdd:TIGR02431   1 SRDFVASLARGLAVIEAFGAERPRLTLTDVAEATGLTRAAARRFLLTLVELGYVTSDGRLFWLTPRVLRLGYAYLSSAPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  110 ATSSQPYLDRMSDQLHEACNMATLEGDDILYIARSATtQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVD 189
Cdd:TIGR02431  81 PKVAQPLLERLSAQTHESCSVAVLDGDEIVYVARSPT-HRIMSVGLSVGTRLPAYCTSMGRVLLAGLDDEELDEYLARST 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  190 LQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEQRFLPIMLD 269
Cdd:TIGR02431 160 LQALTPRTITDRDALLAELLAVRAQGYALVDQELELGLRSIAVPIRNARGQVVAALNVSTHAARTTPEELVERILPLLLE 239

                  ....*....
gi 489458611  270 ASRDLSTQL 278
Cdd:TIGR02431 240 AARELRQLL 248
 
Name Accession Description Interval E-value
pcaR_pcaU TIGR02431
beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this ...
30-278 9.61e-123

beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions]


Pssm-ID: 131484 [Multi-domain]  Cd Length: 248  Bit Score: 350.41  E-value: 9.61e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611   30 DPDFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRTYSLLPKVLTLGHAYLSSTPL 109
Cdd:TIGR02431   1 SRDFVASLARGLAVIEAFGAERPRLTLTDVAEATGLTRAAARRFLLTLVELGYVTSDGRLFWLTPRVLRLGYAYLSSAPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  110 ATSSQPYLDRMSDQLHEACNMATLEGDDILYIARSATtQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVD 189
Cdd:TIGR02431  81 PKVAQPLLERLSAQTHESCSVAVLDGDEIVYVARSPT-HRIMSVGLSVGTRLPAYCTSMGRVLLAGLDDEELDEYLARST 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  190 LQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEQRFLPIMLD 269
Cdd:TIGR02431 160 LQALTPRTITDRDALLAELLAVRAQGYALVDQELELGLRSIAVPIRNARGQVVAALNVSTHAARTTPEELVERILPLLLE 239

                  ....*....
gi 489458611  270 ASRDLSTQL 278
Cdd:TIGR02431 240 AARELRQLL 248
IclR COG1414
DNA-binding transcriptional regulator, IclR family [Transcription];
30-278 7.01e-79

DNA-binding transcriptional regulator, IclR family [Transcription];


Pssm-ID: 441024 [Multi-domain]  Cd Length: 253  Bit Score: 238.95  E-value: 7.01e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  30 DPDFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTD--GRTYSLLPKVLTLGHAYLSST 107
Cdd:COG1414    1 DRSGVQSLERALAILEALAEAGGGLSLSELARRLGLPKSTVHRLLATLEEEGYVERDpeGGRYRLGPRLLELGSAALRRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 108 PLATSSQPYLDRMSDQLHEACNMATLEGDDILYIARsATTQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDH 187
Cdd:COG1414   81 DLRRLARPVLEELAEETGETVHLAVLDGDEVVYVAR-VEGPRPVRVSSRVGSRLPLHATASGKALLAFLPEEELEALLAR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 188 VDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEqRFLPIM 267
Cdd:COG1414  160 AGLPRFTPNTITDPAALRAELAEIRERGYAVDDGELEPGVRAVAAPVFDADGRVVAALSVSGPSSRLTEERLE-ELAPAL 238
                        250
                 ....*....|.
gi 489458611 268 LDASRDLSTQL 278
Cdd:COG1414  239 RAAAREISRAL 249
IclR pfam01614
Bacterial transcriptional regulator; This family of bacterial transcriptional regulators ...
151-277 8.74e-43

Bacterial transcriptional regulator; This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family. These proteins have a Helix-Turn-Helix motif at the N-terminus. However this family covers the C-terminal region that binds to regulatory substrates including Glyoxylate, allantoin/ate, indole, aromatic hydrocarbons, sugar acids, succinic semialdehyde, benzoate derivatives, ascorbic acid, glycerol-3-phosphate, glyceraldehyde-3-phosphate and pyruvate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 426346 [Multi-domain]  Cd Length: 128  Bit Score: 142.42  E-value: 8.74e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  151 ISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSI 230
Cdd:pfam01614   3 LRAYSAIGRRLPLHATAIGKALLAWLDEEELEAYLERYELKRLTPNTITDPEALLEELAQIREQGYAVDREEHELGVRCI 82
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 489458611  231 AVPVYDASGQVLAALNVSTSAGRVARSELEQrFLPIMLDASRDLSTQ 277
Cdd:pfam01614  83 AAPIFDASGDVVAAISVSGPTSRLTEEELDY-LLALLREAARKISRA 128
PRK15090 PRK15090
DNA-binding transcriptional regulator KdgR; Provisional
31-278 1.32e-40

DNA-binding transcriptional regulator KdgR; Provisional


Pssm-ID: 185046 [Multi-domain]  Cd Length: 257  Bit Score: 141.31  E-value: 1.32e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  31 PDFMTSLARGLAVIHAFQERkRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT--YSLLPKVLTLGHAYLSSTP 108
Cdd:PRK15090   7 PDSVSSVLKVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESekYSLTLKLFELGAKALQNVD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 109 LATSSQPYLDRMSDQLHEACNMATLEGDDILYIAR--SATTQRLISvdlSVGGRLPAYCTSMGRILLAALDDVSLHEYLD 186
Cdd:PRK15090  86 LIRSADIQMREISRLTKETIHLGALDEDSIVYIHKidSMYNLRMYS---RIGRRNPLYSTAIGKVLLAWRDRDEVREILS 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 187 HVDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEQrFLPI 266
Cdd:PRK15090 163 GVEFKRSTEKTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERKQE-YVAM 241
                        250
                 ....*....|..
gi 489458611 267 MLDASRDLSTQL 278
Cdd:PRK15090 242 LHTAARKISEQM 253
HTH_ICLR smart00346
helix_turn_helix isocitrate lyase regulation;
34-122 1.59e-26

helix_turn_helix isocitrate lyase regulation;


Pssm-ID: 214629 [Multi-domain]  Cd Length: 91  Bit Score: 99.20  E-value: 1.59e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611    34 MTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT--YSLLPKVLTLGHAYLSSTPLAT 111
Cdd:smart00346   1 IQSLERGLAVLRALAEEPGGLTLAELAERLGLSKSTAHRLLNTLQELGYVEQDGQNgrYRLGPKVLELGQSYLSSLDLRE 80
                           90
                   ....*....|.
gi 489458611   112 SSQPYLDRMSD 122
Cdd:smart00346  81 VAKPVLEELSR 91
 
Name Accession Description Interval E-value
pcaR_pcaU TIGR02431
beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this ...
30-278 9.61e-123

beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions]


Pssm-ID: 131484 [Multi-domain]  Cd Length: 248  Bit Score: 350.41  E-value: 9.61e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611   30 DPDFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRTYSLLPKVLTLGHAYLSSTPL 109
Cdd:TIGR02431   1 SRDFVASLARGLAVIEAFGAERPRLTLTDVAEATGLTRAAARRFLLTLVELGYVTSDGRLFWLTPRVLRLGYAYLSSAPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  110 ATSSQPYLDRMSDQLHEACNMATLEGDDILYIARSATtQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVD 189
Cdd:TIGR02431  81 PKVAQPLLERLSAQTHESCSVAVLDGDEIVYVARSPT-HRIMSVGLSVGTRLPAYCTSMGRVLLAGLDDEELDEYLARST 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  190 LQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEQRFLPIMLD 269
Cdd:TIGR02431 160 LQALTPRTITDRDALLAELLAVRAQGYALVDQELELGLRSIAVPIRNARGQVVAALNVSTHAARTTPEELVERILPLLLE 239

                  ....*....
gi 489458611  270 ASRDLSTQL 278
Cdd:TIGR02431 240 AARELRQLL 248
IclR COG1414
DNA-binding transcriptional regulator, IclR family [Transcription];
30-278 7.01e-79

DNA-binding transcriptional regulator, IclR family [Transcription];


Pssm-ID: 441024 [Multi-domain]  Cd Length: 253  Bit Score: 238.95  E-value: 7.01e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  30 DPDFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTD--GRTYSLLPKVLTLGHAYLSST 107
Cdd:COG1414    1 DRSGVQSLERALAILEALAEAGGGLSLSELARRLGLPKSTVHRLLATLEEEGYVERDpeGGRYRLGPRLLELGSAALRRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 108 PLATSSQPYLDRMSDQLHEACNMATLEGDDILYIARsATTQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDH 187
Cdd:COG1414   81 DLRRLARPVLEELAEETGETVHLAVLDGDEVVYVAR-VEGPRPVRVSSRVGSRLPLHATASGKALLAFLPEEELEALLAR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 188 VDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEqRFLPIM 267
Cdd:COG1414  160 AGLPRFTPNTITDPAALRAELAEIRERGYAVDDGELEPGVRAVAAPVFDADGRVVAALSVSGPSSRLTEERLE-ELAPAL 238
                        250
                 ....*....|.
gi 489458611 268 LDASRDLSTQL 278
Cdd:COG1414  239 RAAAREISRAL 249
IclR pfam01614
Bacterial transcriptional regulator; This family of bacterial transcriptional regulators ...
151-277 8.74e-43

Bacterial transcriptional regulator; This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family. These proteins have a Helix-Turn-Helix motif at the N-terminus. However this family covers the C-terminal region that binds to regulatory substrates including Glyoxylate, allantoin/ate, indole, aromatic hydrocarbons, sugar acids, succinic semialdehyde, benzoate derivatives, ascorbic acid, glycerol-3-phosphate, glyceraldehyde-3-phosphate and pyruvate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 426346 [Multi-domain]  Cd Length: 128  Bit Score: 142.42  E-value: 8.74e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  151 ISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSI 230
Cdd:pfam01614   3 LRAYSAIGRRLPLHATAIGKALLAWLDEEELEAYLERYELKRLTPNTITDPEALLEELAQIREQGYAVDREEHELGVRCI 82
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 489458611  231 AVPVYDASGQVLAALNVSTSAGRVARSELEQrFLPIMLDASRDLSTQ 277
Cdd:pfam01614  83 AAPIFDASGDVVAAISVSGPTSRLTEEELDY-LLALLREAARKISRA 128
PRK15090 PRK15090
DNA-binding transcriptional regulator KdgR; Provisional
31-278 1.32e-40

DNA-binding transcriptional regulator KdgR; Provisional


Pssm-ID: 185046 [Multi-domain]  Cd Length: 257  Bit Score: 141.31  E-value: 1.32e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  31 PDFMTSLARGLAVIHAFQERkRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT--YSLLPKVLTLGHAYLSSTP 108
Cdd:PRK15090   7 PDSVSSVLKVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESekYSLTLKLFELGAKALQNVD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 109 LATSSQPYLDRMSDQLHEACNMATLEGDDILYIAR--SATTQRLISvdlSVGGRLPAYCTSMGRILLAALDDVSLHEYLD 186
Cdd:PRK15090  86 LIRSADIQMREISRLTKETIHLGALDEDSIVYIHKidSMYNLRMYS---RIGRRNPLYSTAIGKVLLAWRDRDEVREILS 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 187 HVDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVARSELEQrFLPI 266
Cdd:PRK15090 163 GVEFKRSTEKTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERKQE-YVAM 241
                        250
                 ....*....|..
gi 489458611 267 MLDASRDLSTQL 278
Cdd:PRK15090 242 LHTAARKISEQM 253
HTH_ICLR smart00346
helix_turn_helix isocitrate lyase regulation;
34-122 1.59e-26

helix_turn_helix isocitrate lyase regulation;


Pssm-ID: 214629 [Multi-domain]  Cd Length: 91  Bit Score: 99.20  E-value: 1.59e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611    34 MTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT--YSLLPKVLTLGHAYLSSTPLAT 111
Cdd:smart00346   1 IQSLERGLAVLRALAEEPGGLTLAELAERLGLSKSTAHRLLNTLQELGYVEQDGQNgrYRLGPKVLELGQSYLSSLDLRE 80
                           90
                   ....*....|.
gi 489458611   112 SSQPYLDRMSD 122
Cdd:smart00346  81 VAKPVLEELSR 91
PRK10163 PRK10163
HTH-type transcriptional repressor AllR;
36-278 6.53e-20

HTH-type transcriptional repressor AllR;


Pssm-ID: 182279 [Multi-domain]  Cd Length: 271  Bit Score: 86.60  E-value: 6.53e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  36 SLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT--YSLLPKVLTLGHAYLSSTPLATSS 113
Cdd:PRK10163  23 ALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLgwWHIGLGVFNVGAAYIHNRDVLSVA 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 114 QPYLDRMSDQLHEACNMATLEGDDILYIARSATtQRLISVDLSVGGRLPAYCTSMGRILLAALDDVSLHEYLDHVDLQPK 193
Cdd:PRK10163 103 GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLEC-KSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQF 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 194 TSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALNVSTSAGRVArselEQRFLP---IMLDA 270
Cdd:PRK10163 182 TPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLT----EDRFVSqgeLVRDT 257

                 ....*...
gi 489458611 271 SRDLSTQL 278
Cdd:PRK10163 258 ARDISTAL 265
PRK11569 PRK11569
glyoxylate bypass operon transcriptional repressor IclR;
12-254 3.50e-19

glyoxylate bypass operon transcriptional repressor IclR;


Pssm-ID: 183206 [Multi-domain]  Cd Length: 274  Bit Score: 84.86  E-value: 3.50e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  12 LAPPIVASPAKRIQALTGDPDF-MTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDGRT- 89
Cdd:PRK11569   1 MVAPIPAKRGRKPAAATAPATGqVQSLTRGLKLLEWIAESNGSVALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELg 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  90 -YSLLPKVLTLGHAYLSSTPLATSSQPYLDRMSDQLHEACNMATLEGDD--ILYIARSATTQrLISVDLSVGGRLPAYCT 166
Cdd:PRK11569  81 hWAIGAHAFIVGSSFLQSRNLLAIVHPILRNLMEDSGETVNLAVLDQSDhqAIIIDQVQCTA-LMRMSAPIGGKLPMHAS 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 167 SMGRILLAALDDVSLHEYLDHVDLQPKTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLRSIAVPVYDASGQVLAALN 246
Cdd:PRK11569 160 GAGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHALGLRCVAACIFDEHREPFAAIS 239

                 ....*...
gi 489458611 247 VSTSAGRV 254
Cdd:PRK11569 240 ISGPISRI 247
PRK09834 PRK09834
DNA-binding transcriptional regulator;
36-278 6.56e-18

DNA-binding transcriptional regulator;


Pssm-ID: 182100 [Multi-domain]  Cd Length: 263  Bit Score: 80.81  E-value: 6.56e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611  36 SLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGY---ATTDGRtYSLLPKVLTLGHAYLSSTPLATS 112
Cdd:PRK09834   9 GLSRGLMVLRALNRLDGGATVGLLAELTGLHRTTVRRLLETLQEEGYvrrSASDDS-FRLTLKVRQLSEGFRDEQWISAL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 113 SQPYLDRMSDQLHEACNMATLEGDDIlyIARSATTQR-LISVDLS-VGGRLPAYCTSMGRILLAALDDVSLHEYLDHVDL 190
Cdd:PRK09834  88 AAPLLGDLLRRVVWPTDLTTLDVDAM--VIRETTHRFsPLSFHRAmVGRRLPLLLTAAGRAYLAFCPEEEREALLELLAS 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489458611 191 QP-KTSRTIRTPEALLECLQLVRQQGWCIVDQELEQGLR--SIAVPVYdASGQVLAALNVSTSAGRVARSELEQRFLPIM 267
Cdd:PRK09834 166 RPgDEDQLARDPARLEAMLARTRKRGYGENYGGWDQQPKiaSIAVPVR-SGQRVLGCLNLVYIASAMSIEEAAKRYLPAL 244
                        250
                 ....*....|.
gi 489458611 268 LDASRDLSTQL 278
Cdd:PRK09834 245 QRAAKQIEAGV 255
HTH_IclR pfam09339
IclR helix-turn-helix domain;
36-87 1.12e-11

IclR helix-turn-helix domain;


Pssm-ID: 430539 [Multi-domain]  Cd Length: 52  Bit Score: 58.57  E-value: 1.12e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 489458611   36 SLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGYATTDG 87
Cdd:pfam09339   1 SLDRALAILDALAEAPGPLTLTEIARRTGLPKSTAHRLLQTLVELGYVEQDP 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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