|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
13-821 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1475.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 13 DRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASI 92
Cdd:PRK05560 3 DRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 93 YDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPN 172
Cdd:PRK05560 83 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 173 LLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIR 252
Cdd:PRK05560 163 LLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEE----LMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 253 MRGVVEVEEDsRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSsDRVGLRIVIEIKRDAVAKVVINNLY 332
Cdd:PRK05560 239 MRAKAEIEEI-KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDES-DRDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 333 KHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASE 412
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 413 TVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGD 492
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 493 DRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTT 572
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 573 QGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVN 652
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 653 LRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREG-TYLLVATSGGY 731
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQEILTVTENGY 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 732 AKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDT 811
Cdd:PRK05560 715 GKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDK 794
|
810
....*....|
gi 489495369 812 LLAIARNAEE 821
Cdd:PRK05560 795 VVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-816 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1362.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 1 MTDTTLPpddslDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET 80
Cdd:COG0188 1 MSDPPPA-----ERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 81 MGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV 160
Cdd:COG0188 76 MGKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 161 QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGT 240
Cdd:COG0188 156 QEPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEE----LMEYIPGPDFPTGGIIVGREGI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSsDRVGLRIVIEIKR 320
Cdd:COG0188 232 REAYETGRGSIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDES-DRDGMRIVIELKR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 321 DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA 400
Cdd:COG0188 311 DANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDN 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 401 LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480
Cdd:COG0188 391 IDEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIK 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV 560
Cdd:COG0188 471 EELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 561 CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF 640
Cdd:COG0188 551 ASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 641 DSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720
Cdd:COG0188 631 SNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVDEE 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG 800
Cdd:COG0188 709 DDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQG 788
|
810
....*....|....*.
gi 489495369 801 VRLMNLGEGDTLLAIA 816
Cdd:COG0188 789 VRLIRLDEGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
15-820 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1335.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 15 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD 94
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 95 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLL 174
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 175 ANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAvmgrVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMR 254
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEV----IKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 255 GVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQsSDRVGLRIVIEIKRDAVAKVVINNLYKH 334
Cdd:TIGR01063 237 ARAEIEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 335 TQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETV 414
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 415 DIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDR 494
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 495 RTRIIAADGDVSD-EDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQ 573
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 574 GRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNL 653
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 654 RDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAK 733
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 734 RTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLL 813
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 489495369 814 AIARNAE 820
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
37-486 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 683.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 37 VGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNF 116
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 117 GSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRE 196
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 197 LADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDsRGRTSLVITELPY 276
Cdd:cd00187 161 VIDALRALIDNPEASIDE----LMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDD-EGRNTIEITELPY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 277 QVNHDNFITSIAEQVRDGKLAGISNIEDQsSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIV-DGVPRT 355
Cdd:cd00187 236 QVNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 356 LRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASetvDIARAGLIELL---DIDEIQA 432
Cdd:cd00187 315 LNLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQA 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 489495369 433 QAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEI 486
Cdd:cd00187 392 DAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
18-476 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 651.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 18 VDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLV 97
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 98 RMAQPWSLRYPLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLAN 176
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 177 GSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQgtadayktgrgSIRMRGV 256
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDE----LMMIPWGPDFPTGGEIVGPG-----------KYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 257 VEVEEDsrgrTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQ 336
Cdd:smart00434 226 IEIEDD----NTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTK 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 337 LQTSFGANMLAIVD-GVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKAN-ERAHILRGLVKALDALDEVIALIRAS-ET 413
Cdd:smart00434 302 LQTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSkDL 381
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489495369 414 VDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQR 476
Cdd:smart00434 382 AKEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
39-483 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 613.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 39 RALPEVRDGLKPVHRRVLYAMFDSgFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGS 118
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 119 -PGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLREL 197
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 198 ADAVFWALENhdadEEETLaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEdsrgRTSLVITELPYQ 277
Cdd:pfam00521 160 IDALIALLDG----PEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 278 VNHDNFITSIAEQVRDGKLAGISNIEDQsSDRvGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLR 357
Cdd:pfam00521 230 VWTSDLIEKIEELVKNGKIKGISDIRDE-SDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 358 LDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIEllDIDEIQAQAILD 437
Cdd:pfam00521 308 LKEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLD 385
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 489495369 438 MQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDEL 483
Cdd:pfam00521 386 MRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
14-129 |
8.62e-87 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 300.49 E-value: 8.62e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 14 RIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIY 93
Cdd:NF038098 1 RIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIY 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 489495369 94 DTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRY 129
Cdd:NF038098 81 DTLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
13-821 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1475.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 13 DRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASI 92
Cdd:PRK05560 3 DRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 93 YDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPN 172
Cdd:PRK05560 83 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 173 LLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIR 252
Cdd:PRK05560 163 LLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEE----LMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 253 MRGVVEVEEDsRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSsDRVGLRIVIEIKRDAVAKVVINNLY 332
Cdd:PRK05560 239 MRAKAEIEEI-KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDES-DRDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 333 KHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASE 412
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 413 TVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGD 492
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 493 DRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTT 572
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 573 QGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVN 652
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 653 LRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREG-TYLLVATSGGY 731
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQEILTVTENGY 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 732 AKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDT 811
Cdd:PRK05560 715 GKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDK 794
|
810
....*....|
gi 489495369 812 LLAIARNAEE 821
Cdd:PRK05560 795 VVSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-816 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1362.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 1 MTDTTLPpddslDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET 80
Cdd:COG0188 1 MSDPPPA-----ERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 81 MGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV 160
Cdd:COG0188 76 MGKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 161 QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGT 240
Cdd:COG0188 156 QEPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEE----LMEYIPGPDFPTGGIIVGREGI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSsDRVGLRIVIEIKR 320
Cdd:COG0188 232 REAYETGRGSIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDES-DRDGMRIVIELKR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 321 DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA 400
Cdd:COG0188 311 DANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDN 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 401 LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480
Cdd:COG0188 391 IDEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIK 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV 560
Cdd:COG0188 471 EELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 561 CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF 640
Cdd:COG0188 551 ASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 641 DSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720
Cdd:COG0188 631 SNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVDEE 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG 800
Cdd:COG0188 709 DDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQG 788
|
810
....*....|....*.
gi 489495369 801 VRLMNLGEGDTLLAIA 816
Cdd:COG0188 789 VRLIRLDEGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
15-820 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1335.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 15 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD 94
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 95 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLL 174
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 175 ANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAvmgrVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMR 254
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEV----IKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 255 GVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQsSDRVGLRIVIEIKRDAVAKVVINNLYKH 334
Cdd:TIGR01063 237 ARAEIEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 335 TQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETV 414
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 415 DIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDR 494
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 495 RTRIIAADGDVSD-EDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQ 573
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 574 GRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNL 653
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 654 RDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAK 733
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 734 RTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLL 813
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 489495369 814 AIARNAE 820
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
7-751 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 869.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 7 PPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHP 86
Cdd:PRK05561 2 PDMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 87 HGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVL 166
Cdd:PRK05561 82 HGDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 167 PSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDAdeeeTLAAVMGRVKGPDFPTAGLIVGS-QGTADAYK 245
Cdd:PRK05561 162 PARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDA----TLEELMEFVPGPDFPTGGEIITGrDGIRKAYE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 246 TGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAV-A 324
Cdd:PRK05561 238 TGRGSIRVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVdP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 325 KVVINNLYKHTQLQTSFGANMLAI-VDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDE 403
Cdd:PRK05561 318 EALMNHLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 404 VIALIRASetvDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDEL 483
Cdd:PRK05561 398 VIRIIRES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKEL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 484 AEIVDRHGDDRRTRIIAADGDVSD--EDLIAREDVVVTITETGYAKRTKtdlyrsqkrgGKGVQGAGL--KQDDIVAHFF 559
Cdd:PRK05561 475 KADAKKFGDPRRTPIEEAEEAIAIdeEALIPDEPVTVVLSKKGWVRRAK----------GHSIDASGLsfKEGDSLLFAF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 560 VCSTHDLILFFTTQGRVYRAKAYDLPEASRTarGQHVANLLAFQPEERIAQVIQirgYTDAPYLVLATRNGLVKKSKLTD 639
Cdd:PRK05561 545 EARTTDKLLLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLED 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 640 FDSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDeaLRPMGRATsGVQGMRFNI-DDRLLSLNVVR 718
Cdd:PRK05561 620 LVARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSE--LPELGKGK-GVKLINLPKdDDGLVDLRVLN 696
|
730 740 750
....*....|....*....|....*....|....*
gi 489495369 719 EGTYLLVATSG-GYAKRTAIEEYPVQG-RGGKGVL 751
Cdd:PRK05561 697 PEDGLVLLTAGkRKLKLKPSELEKYRGkRARRGRL 731
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
37-486 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 683.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 37 VGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNF 116
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 117 GSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRE 196
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 197 LADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDsRGRTSLVITELPY 276
Cdd:cd00187 161 VIDALRALIDNPEASIDE----LMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDD-EGRNTIEITELPY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 277 QVNHDNFITSIAEQVRDGKLAGISNIEDQsSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIV-DGVPRT 355
Cdd:cd00187 236 QVNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 356 LRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASetvDIARAGLIELL---DIDEIQA 432
Cdd:cd00187 315 LNLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQA 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 489495369 433 QAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEI 486
Cdd:cd00187 392 DAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
18-476 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 651.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 18 VDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLV 97
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 98 RMAQPWSLRYPLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLAN 176
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 177 GSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQgtadayktgrgSIRMRGV 256
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDE----LMMIPWGPDFPTGGEIVGPG-----------KYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 257 VEVEEDsrgrTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQ 336
Cdd:smart00434 226 IEIEDD----NTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTK 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 337 LQTSFGANMLAIVD-GVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKAN-ERAHILRGLVKALDALDEVIALIRAS-ET 413
Cdd:smart00434 302 LQTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSkDL 381
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489495369 414 VDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQR 476
Cdd:smart00434 382 AKEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
39-483 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 613.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 39 RALPEVRDGLKPVHRRVLYAMFDSgFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGS 118
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 119 -PGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLREL 197
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 198 ADAVFWALENhdadEEETLaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEdsrgRTSLVITELPYQ 277
Cdd:pfam00521 160 IDALIALLDG----PEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 278 VNHDNFITSIAEQVRDGKLAGISNIEDQsSDRvGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLR 357
Cdd:pfam00521 230 VWTSDLIEKIEELVKNGKIKGISDIRDE-SDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 358 LDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIEllDIDEIQAQAILD 437
Cdd:pfam00521 308 LKEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLD 385
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 489495369 438 MQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDEL 483
Cdd:pfam00521 386 MRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
20-750 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 612.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 20 IQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRM 99
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 100 AQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEV 259
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDK----LMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 260 EEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDqSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQT 339
Cdd:TIGR01061 242 EVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRD-ESDRNGIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 340 SFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRI- 498
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIe 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 499 -IAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKrggkgVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVY 577
Cdd:TIGR01061 481 dFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSK-----YTDFGSKDDDILFAQTIANTTDQILIFTSLGNII 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 578 RAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGY-TDAPYLVLATRNGLVKKSKLTDFDSNR-SGGIVAVNLRD 655
Cdd:TIGR01061 556 NIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFdVDQPILVLASKLGMVKRIELTELNIKRnSKATLCIKLKD 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 656 NDELVGAVLCSADDDLLLVSANGQSIRFSaTDEaLRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRT 735
Cdd:TIGR01061 636 KDHLISAFLQQKDKLICLVSDLGYALVFH-TNE-IPVVGAKAAGVKGMKLKEDDQVKSGVIFEANESLVLLTQRGSVKRL 713
|
730
....*....|....*
gi 489495369 736 AIEEYPVQGRGGKGV 750
Cdd:TIGR01061 714 SISELVVTSRAATGK 728
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
8-722 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 591.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 8 PDDSldRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPH 87
Cdd:PRK13979 8 PKDN--NIIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPH 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 88 GDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLP 167
Cdd:PRK13979 86 GDSSVYDAMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 168 SRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaaVMGRVKGPDFPTAGLIVGSQGTADAYKTG 247
Cdd:PRK13979 166 ARYPNLLVNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKE----LMNYIKGPDLPTGGILIGKKSLLSAYETG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 248 RGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGK----LAGISNIEDQsSDRVGLRIVIEIKRDA- 322
Cdd:PRK13979 242 EGKVTLRAKTKIEKLENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDE-SDRNGIRAVIEFKKSAd 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 323 --VAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA 400
Cdd:PRK13979 321 edVAEKVLKYLYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGI 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 401 LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480
Cdd:PRK13979 401 MDEIIKTIRSSKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIK 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 481 DELAEIVDRHGDDRRTRIIAADG----DVsdEDLIAREDVVVTITETGYAKRTKTDLYrsqKRGGKGVQGAGLKQDDIVA 556
Cdd:PRK13979 481 KELKEVKEKYGDERRTSIIEDDEkakiDV--EELIVVEDVVITLSNEGFIKRIPLKSY---NRSNSNVEDIEYREGDFNK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 557 HFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAF--QPEERIAQVIQIRGYTDAPYLVLATRNGLVKK 634
Cdd:PRK13979 556 FLIQSNTKDTLLIFTDKGNMYQIKGINIPEFKWKEKGERLDEIIKGidLESEKIIEAYSIEDFTPQKDFIFITDSGGIKK 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 635 SKLTDFDSNRSgGIVAVNLRDNDELVGA--VLCSADDDLLLVSANgQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLL 712
Cdd:PRK13979 636 TSLDKFVTNYT-KLMALKLKKGEKLIKVklVDRTREEKFIKIKTK-KGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIK 713
|
730
....*....|
gi 489495369 713 SLNVVREGTY 722
Cdd:PRK13979 714 KVDFCDNYEY 723
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
15-687 |
9.54e-164 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 493.66 E-value: 9.54e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 15 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD 94
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 95 TLVRMAQPWSLRYPLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNL 173
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPdDPKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 174 LANGSGGIAVGMATNIPPHNLRELADAVFWALENHDAdeeeTLAAVMGRVKGPDFPTAGLIVGSQGTADA-YKTGRGSIR 252
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKA----GLDDILNIVQGPDFPTEAEIIDKAEEIRKiYETGRGSFR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 253 MRGVVEVEEdsrgrTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAV-AKVVINNL 331
Cdd:TIGR01062 237 MRARWKKED-----GQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVdPDIVMEHL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 332 YKHTQLQTSFGANMLAI-VDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRA 410
Cdd:TIGR01062 312 FATTDLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIRE 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 411 SetvDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRH 490
Cdd:TIGR01062 392 E---DEPKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKY 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 491 GDDRRTRIIAAD--GDVSDEDLIAREDVVVTITETGYAkrtktdlyRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLIL 568
Cdd:TIGR01062 469 GLARRSSLEEREeaKQVSEIDMIPKEPVTIILSKMGWV--------RSAKGHDIDLSTLKYKAGDSEKAIIEGKSNQKVV 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 569 FFTTQGRVYRAKAYDLPEASRTarGQHVANLLAFQPEERIAQVIQirgYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGI 648
Cdd:TIGR01062 541 FIDSTGRSYALDPDNLPSARGQ--GEPLTGKLLLPIGATITNILM---YSPNQLLLMASDAGYGFLCNFNDLIARNKAGK 615
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 489495369 649 VAVNLRDNDELVGAVLCSADDDLLL-VSANGQSIRFSATD 687
Cdd:TIGR01062 616 ALINLPENASVIAPLPVNGDSDMIAaITEAGRMLVFPIDD 655
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
14-129 |
8.62e-87 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 300.49 E-value: 8.62e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 14 RIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIY 93
Cdd:NF038098 1 RIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIY 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 489495369 94 DTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRY 129
Cdd:NF038098 81 DTLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
17-586 |
8.77e-81 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 272.74 E-value: 8.77e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 17 PVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF--DSGfrpdRSHaKSARSVAETMgNYHPHGDASIYD 94
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFemHDG----KFH-KVANVVGNTM-KYHPHGDASIYE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 95 TLVRMAQpwslRYPLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLreIDEETVDFIPNYDGRVQEPTVLPSRFPNL 173
Cdd:PRK09631 75 ALVNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 174 LANGSGGIAVGMATNIPPHNLRELADAVFWALEnhdaDEEETLAavmgrvkgPDFPTAGLIvgsqgTADAYKTGRGSIRM 253
Cdd:PRK09631 149 LIQGAEGIAVGMATKILPHNFNEILQAVKSELL----GESFALY--------PDFPTGGIV-----DVSEYADGNGKVLV 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 254 RGVVEVEEDSRgrtsLVITELPYQVNHDNFITSIAEQVRDGKLAgISNIEDQSSDRVGlrivIEIK--RDAVAKVVINNL 331
Cdd:PRK09631 212 RAKIETKDEKT----IVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAENVE----IEIKlpRGVYASEVIEAL 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 332 YKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAH--------ILRGLVKALDALDe 403
Cdd:PRK09631 283 YAYTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIFaktleqifIEERIYKRIETIS- 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 404 vialiRASETVDIARAGLI----ELL-DIDEIQAQAILDMQLRRLAALerqriidDLAKIEAEIADLEDILAKPERQ--- 475
Cdd:PRK09631 362 -----SEEDVISIVLSELKpfkeELSrDVTEEDIENLLKIPIRRISLF-------DIDKNQKEIRILNKELKSVEKNlks 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 476 -RGIVRDELAEIVDRHGDD--RRTRIiaadgdvsdeDLIAREDVVVTITEtgyakrtKTDLYRSQKRGGKGVQGAGlkQD 552
Cdd:PRK09631 430 iKGYAINFIDKLLAKYSKEypRKTEI----------SLIKSVDVREIATK-------NLKVYYDLKTGFVGTSVKD--GE 490
|
570 580 590
....*....|....*....|....*....|....
gi 489495369 553 DIVAhffvCSTHDLILFFTTQGRvYRAKayDLPE 586
Cdd:PRK09631 491 FIGN----ASYYDKILVIRKDGT-YVVK--NIPD 517
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
28-575 |
5.00e-69 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 245.30 E-value: 5.00e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 28 YIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGfrpDRSHAKSARSVAETMgNYHPHGDASIYDTLVRMAQpwslRY 107
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMD---DGRYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ----KD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 108 PLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLreIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMA 186
Cdd:PRK12758 103 LLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 187 TNIPPHNLRELADAVFWALENhdadEEETLAavmgrvkgPDFPTAGLIVGSqgtadAYKTGR--GSIRMRGVVEvEEDSR 264
Cdd:PRK12758 181 TKILPHNFNELIDASIAYLKG----KEFKLY--------PDFPTGGIIDVS-----NYNDGErgGRVRVRAKIE-KLDKK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 265 grtSLVITELPYQVNHDNFITSIAEQVRDGKLAgISNIEDQSSDRVglRIVIEIKRDAVAKVVINNLYKHTQLQTSFGAN 344
Cdd:PRK12758 243 ---TLVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAADV--EILVHLAPGVSPDKTIDALYAFTDCEVSISPN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 345 MLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAH------------ILRGLVKALDaLDEVIA------ 406
Cdd:PRK12758 317 ACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifieerIYKEIEEAET-WEAVIEaidkgl 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 407 ------LIRASETVDIARaglieLLDIdeiqaqaildmQLRRLAALERQRIIDDLAKIEAEIADLEDILAKperqrgIVR 480
Cdd:PRK12758 396 epfkkqFIREVTEDDIVR-----LTEI-----------KIKRISKFDSDKADELIARLEAEIAEVKHHLAH------LTD 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 481 ---DELAEIVDRHGDD--RRTRIIAADgdvsdedliaredvvvTITETGYAKRTkTDLYRSQKrggKGVQGAGLKQDDIV 555
Cdd:PRK12758 454 yaiAYFTNLKKKYGKGreRKTEIRNFD----------------TIEATKVVEAN-QKLYVNRE---EGFIGTGLKKDEYV 513
|
570 580
....*....|....*....|
gi 489495369 556 AHffvCSTHDLILFFTTQGR 575
Cdd:PRK12758 514 AD---CSDIDDVIVFRRDGK 530
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
19-363 |
3.35e-55 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 198.20 E-value: 3.35e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 19 DIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF--DSGfrpdRSHaKSARSVAETMGnYHPHGDASIYDTL 96
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFrmDDG----KMH-KVANIAGRTMA-LHPHGDAPIVEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 97 VRMAQpwslRYPLVDGQGNFGSP-GNDPPAAMRYTEARLTPLAMEMLREIDeeTVDFIPNYDGRVQEPTVLPSRFPNLLA 175
Cdd:PRK09630 77 VVLAN----KGYLIDTQGNFGNPlTGDPHAAARYIEARLSPLAKEVLFNTD--LMTFHDSYDGREKEPDILPAKLPLLLL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 176 NGSGGIAVGMATNIPPHNLRELADAVFWALEnhdaDEEETLAavmgrvkgPDFPTAGLIVGSQgtadaYKTGRGSIRMRG 255
Cdd:PRK09630 151 HGVDGIAVGMTTKIFPHNFCELLEAQIAILN----DQPFTLL--------PDFPSGGTMDASE-----YQDGLGSITLRA 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 256 VVEVEEDSrgrtSLVITELPYQVNHDNFITSIAEQVRDGKLAgISNIEDQSSDRVglRIVIEIKRDAVAKVVINNLYKHT 335
Cdd:PRK09630 214 SIDIINDK----TLLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFSTDLP--HIEIKLPKGIYAKDLLRPLFTHT 286
|
330 340
....*....|....*....|....*...
gi 489495369 336 QLQTSFGANMLAIVDGVPRTLRLDQLIR 363
Cdd:PRK09630 287 ECQVILTSRPTAIYQNKPVETSISEILR 314
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
19-469 |
2.51e-48 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 177.56 E-value: 2.51e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 19 DIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSArSVAE--TMGNYHpHGDASIYDTL 96
Cdd:PHA02592 7 SLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVA-AIAGgvADLGYH-HGETSAQDAG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 97 VRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDeetvdfipnYDGRVQEPTVLPSRF-----P 171
Cdd:PHA02592 85 ALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDED---------LAPVHEDPEHIPPAFylpiiP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 172 NLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEtlaavmgrVKGPDFptaglivgsqgTADAYKTGRGSI 251
Cdd:PHA02592 156 MVLLNGVSGIATGYATNILPHSPKSVIKAVLAALNGKDITEPK--------VQFPEF-----------KGEVVEIEPGSY 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 252 RMRGVVEVEedsrGRTSLVITELPYQVNHDNFITSIAEQVRDGKlagISNIEDQSSDrvGLRIVIEIKRDAVAKVVINNL 331
Cdd:PHA02592 217 EIRGTYELN----GKTKLHITEIPVKYDRETYVAVLDPLEEKGK---IVSYDDCTED--GFRFKVTLKREENEEATHEKI 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 332 YKHTQLQTSFGANMLAIV-DG-VPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILrgLVKAlDALDEVIALIR 409
Cdd:PHA02592 288 MKDFGLIERVSQNITVINeNGkLKVYENAEDLIRDFVEIRKTYVQKRIQYEIKETEEAFDLA--LAKA-EFIKRVIAGEI 364
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489495369 410 ASEtvDIARAGLIELL---DIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAE-------------IADLEDIL 469
Cdd:PHA02592 365 VLQ--GKTRSELTEELsdnKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEKEheywkkttakkeyIKDLEELK 438
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
39-472 |
4.47e-27 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 119.00 E-value: 4.47e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 39 RALPEVRDGLKPVHRRVLYAMFdsgfrpdRSHAKSARSVAETMG------NYHpHGDASIYDTLVRMAQPW------SLR 106
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACF-------KRNLKNEIKVAQLSGyvsehsAYH-HGEQSLQQTIVGMAQNFvgsnniNLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 107 YPlvDGQgnFGSP---GNDPPAAmRYTEARLTPLAmemlREIDEETVDFIPNY---DGRVQEPTVLPSRFPNLLANGSGG 180
Cdd:PTZ00108 752 YP--CGQ--FGSRlqgGKDHAAA-RYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPFYYVPIIPMVLVNGAEG 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 181 IAVGMATNIPPHNLRELADAVfwalenhdadeeetLAAVMGRVKGPDFPTAgliVGSQGTADayKTGRGSIRMRGVVEVe 260
Cdd:PTZ00108 823 IGTGFSTSIPNYNPLDIIDNL--------------RRRLNGEEVRPLVPWY---RGFKGTIE--RNPKGKFISKGIYEK- 882
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 261 edsRGRTSLVITELPYQV---NHDNFITSiaEQVRDGKLagISNIEDQSSDrVGLRIVIEIKRDAVAKVVINNLYKHTQL 337
Cdd:PTZ00108 883 ---VPDGTVEITELPIGKwteDYKEFLES--ETLKEKDV--IVDYRDYSTA-NTVHFTVKLNDGVLEQWEEEGIEKVFKL 954
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 338 QTSFGA-NMLAIVDG--VPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKaldaldeVIALIRaSETV 414
Cdd:PTZ00108 955 KSTISTtNMVLFDENgkIKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVR-------FIKHVI-NGEL 1026
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489495369 415 DIARA---GLIELLD------IDEIQ--AQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKP 472
Cdd:PTZ00108 1027 VITNAkkkDLVKELKklgyvrFKDIIkkKSEKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMP 1095
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
39-392 |
2.05e-26 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 116.73 E-value: 2.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 39 RALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGnYHpHGDASIYDTLVRMAQPW------SLRYPlvdg 112
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFACFKRNLKSEIKVAQLSGYVAEHSA-YH-HGEASLASTIIGMAQDFvgsnniNLLTP---- 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 113 QGNFGSP---GNDpPAAMRYTEARLTPLAMEMLREIDEETVDFIpNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 189
Cdd:PLN03128 747 SGQFGTRlqgGKD-AASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGIGTGWSTFI 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 190 PPHNLRELADAVFWALenhdadEEETLAAVMGRVKGpdFptAGLIvgsqgTADAYKTGRGSIrMRGVVEVEEDsrgrTSL 269
Cdd:PLN03128 825 PNYNPRDIIANIRRLL------RGEELEPMHPWYRG--F--KGTI-----TEVSTSRSGSYT-VTGIIEQIGD----TTI 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 270 VITELPYQV---NHDNFITSIAEQVRDgKLAGISNIEDQSSDrVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFG-ANM 345
Cdd:PLN03128 885 RITELPVRKwtqDYKEFLEALLTGTKK-KEPEIKDFKENHTD-TTVHFTVTLSEEKMARALAEGLEKKFKLSTTIStSNM 962
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 489495369 346 LAI-VDGVPRTLRL-DQLIRYYVDHQLDVIVRRTTYRLRKANERAHILR 392
Cdd:PLN03128 963 HLFdKDGKIKKYDSpEDILEEFFHLRLDLYVKRKEVLLENLEYELKKLD 1011
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
39-465 |
4.60e-21 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 99.55 E-value: 4.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 39 RALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAEtMGNYHpHGDASIYDTLVRMAQPW--SLRYPLVDGQGNF 116
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQLSGYVSE-HSAYH-HGEQSLASTIIGMAQDFvgSNNINLLLPNGQF 775
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 117 G--SPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIpNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNL 194
Cdd:PLN03237 776 GtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFIPNYNP 854
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 195 RELADAVFWALenhdaDEEETLaavmgrvkgpdfPTAGLIVGSQGTADAYKTGRGSIR--MRGVVEVEEDsrgrTSLVIT 272
Cdd:PLN03237 855 RDIVANIRRLL-----NGESME------------PMHPWYRGFKGTIEKTASKEGGCTytITGLYEEVDE----TTLRIT 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 273 ELP---YQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVgLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIV 349
Cdd:PLN03237 914 ELPirrWTDDYKEFLESLKTDNNKNKDPFIKDVKAYNDDTT-VHFEVILSEENMLAAKQEGLLKKFKLTTTISTSNMHLF 992
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 350 D---GVPRTLRLDQLIRYYVDHQLDVIVRRTT-------YRLRKANERAHILRGLV---------KALDALDEVIA---- 406
Cdd:PLN03237 993 DskgVIKKYDTPEQILEEFFHLRLEYYEKRKEvllknleFELLKLENKVRFILAVVdgeiivnnrKKADLVEELRQkgft 1072
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489495369 407 -LIRASETVDIARAGLIEllDIDEIQAQA---------------ILDMQLRRLAALERQRIIDDLAKIEAEIADL 465
Cdd:PLN03237 1073 pFPKKAKSVEAAVAGATD--DAAEEEEEIdvssssgvrgsdydyLLSMAIGTLTLEKVQELCADRDKLNIEVEDL 1145
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
515-562 |
2.27e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 56.34 E-value: 2.27e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 489495369 515 DVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCS 562
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
722-769 |
3.51e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 52.87 E-value: 3.51e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 489495369 722 YLLVATSGGYAKRTAIEEYPVQGRGGKGVlTVMYDRRRGRLVGALIVD 769
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGV-KGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
669-718 |
5.08e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.79 E-value: 5.08e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 489495369 669 DDLLLVSANGQSIRFSATDeaLRPMGRATSGVQGMRFNIDDRLLSLNVVR 718
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSE--IREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
773-817 |
5.94e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.41 E-value: 5.94e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 489495369 773 ELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIAR 817
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
565-615 |
3.83e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 47.10 E-value: 3.83e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 489495369 565 DLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLlafQPEERIAQVIQIR 615
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINL---KEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
622-666 |
2.17e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 45.17 E-value: 2.17e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 489495369 622 YLVLATRNGLVKKSKLTDFDSNRSG--GIVAVNLRDNDELVGAVLCS 666
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGakGVKGINLKEGDKVVSVLVVN 48
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
378-515 |
5.17e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.41 E-value: 5.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 378 TYRLRKANERA---HILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDEI---------QAQAILDMQLRRLAA 445
Cdd:PRK02224 166 EYRERASDARLgveRVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEieryeeqreQARETRDEADEVLEE 245
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489495369 446 LERQRiiDDLAKIEAEIADLEDILAKPERQRGIVRDELA---EIVDRHGDDRRTRIIAAD-GDVSDEDLIARED 515
Cdd:PRK02224 246 HEERR--EELETLEAEIEDLRETIAETEREREELAEEVRdlrERLEELEEERDDLLAEAGlDDADAEAVEARRE 317
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
380-539 |
5.25e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 380 RLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIEllDIDEIQAQ-AILDMQLRRLAALERQriiddLAKI 458
Cdd:COG4913 625 ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIAELEAElERLDASSDDLAALEEQ-----LEEL 697
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 459 EAEIADLEDILAKPERQRGIVRDELAEIVDRHgDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQK 538
Cdd:COG4913 698 EAELEELEEELDELKGEIGRLEKELEQAEEEL-DELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERID 776
|
.
gi 489495369 539 R 539
Cdd:COG4913 777 A 777
|
|
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
625-785 |
6.42e-03 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 40.36 E-value: 6.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 625 LATRNGLVKkskltdFDSN-----RSGGIVAVNLRDNDelVGAVLCSADDDLLLVSANGQSiRFSATDEALRPMGRATSg 699
Cdd:COG3292 51 IGTEDGLNR------YDGYefkvfRHDPGDPNSLPSNY--IRALLEDSDGRLWIGTDGGLS-RYDPKTDKFTRYPLDPG- 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489495369 700 vqgmrfNIDDRLLSLNVVREGTyLLVATSGG---YAKRT-AIEEYPVQGRGGKGVLTVMYDRRrgrlvGALIVDDDSELY 775
Cdd:COG3292 121 ------LPNNSIRSIAEDSDGN-IWVGTSNGlyrYDPKTgKFKRFTLDGLPSNTITSLAEDAD-----GNLWVDSDGNLW 188
|
170
....*....|
gi 489495369 776 AVTSGGGVIR 785
Cdd:COG3292 189 IGTDGNGLYR 198
|
|
| |
