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Conserved domains on  [gi|489508497|ref|WP_003413363|]
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MULTISPECIES: haloalkane dehalogenase [Mycobacterium]

Protein Classification

haloalkane dehalogenase( domain architecture ID 11479996)

haloalkane dehalogenase catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 4-300 5.48e-173

haloalkane dehalogenase; Provisional


:

Pssm-ID: 235135  Cd Length: 295  Bit Score: 480.26  E-value: 5.48e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   4 FGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSgpdrYSY 83
Cdd:PRK03592   1 FGVEPPGEMRRVEVLGSRMAYIETGEGDPIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKPDID----YTF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  84 GEQRDFLFALWDALDLgDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQ-GEP 162
Cdd:PRK03592  77 ADHARYLDAWFDALGL-DDVVLVGHDWGSALGFDWAARHPDRVRGIAFMEAIVRPMTWDDFPPAVRELFQALRSPGeGEE 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 163 MALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNgGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFI 242
Cdd:PRK03592 156 MVLEENVFIERVLPGSILRPLSDEEMAVYRRPFPT-PESRRPTLSWPRELPIDGEPADVVALVEEYAQWLATSDVPKLLI 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489508497 243 NAEPGAII-TGRIRDYVRSWPNQTEITV--PGVHFVQEDSPEEIGAAIAQFVRRLRSAAGV 300
Cdd:PRK03592 235 NAEPGAILtTGAIRDWCRSWPNQLEITVfgAGLHFAQEDSPEEIGAAIAAWLRRLRLAVSA 295
 
Name Accession Description Interval E-value
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 4-300 5.48e-173

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 480.26  E-value: 5.48e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   4 FGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSgpdrYSY 83
Cdd:PRK03592   1 FGVEPPGEMRRVEVLGSRMAYIETGEGDPIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKPDID----YTF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  84 GEQRDFLFALWDALDLgDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQ-GEP 162
Cdd:PRK03592  77 ADHARYLDAWFDALGL-DDVVLVGHDWGSALGFDWAARHPDRVRGIAFMEAIVRPMTWDDFPPAVRELFQALRSPGeGEE 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 163 MALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNgGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFI 242
Cdd:PRK03592 156 MVLEENVFIERVLPGSILRPLSDEEMAVYRRPFPT-PESRRPTLSWPRELPIDGEPADVVALVEEYAQWLATSDVPKLLI 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489508497 243 NAEPGAII-TGRIRDYVRSWPNQTEITV--PGVHFVQEDSPEEIGAAIAQFVRRLRSAAGV 300
Cdd:PRK03592 235 NAEPGAILtTGAIRDWCRSWPNQLEITVfgAGLHFAQEDSPEEIGAAIAAWLRRLRLAVSA 295
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 12-294 1.23e-28

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 109.32  E-value: 1.23e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  12 PKYLEIAGKRMAYIDEG-KGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLspsgPDRYSYGEQRDFL 90
Cdd:COG0596    4 PRFVTVDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKP----AGGYTLDDLADDL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  91 FALWDALDLGDhVVLVLHDWGSALGFDWANQHRDRVQGIAfmeaivtpmtwadwppavrgvfqgfrspqgepmalehnif 170
Cdd:COG0596   80 AALLDALGLER-VVLVGHSMGGMVALELAARHPERVAGLV---------------------------------------- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 171 vervlpgailrqLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDgepaevvalvnEYRSWLEETDMPKLFINAEPGAII 250
Cdd:COG0596  119 ------------LVDEVLAALAEPLRRPGLAPEALAALLRALART-----------DLRERLARITVPTLVIWGEKDPIV 175

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489508497 251 TGRI-RDYVRSWPNQTEITVPGV-HFVQEDSPEEIGAAIAQFVRRL 294
Cdd:COG0596  176 PPALaRRLAELLPNAELVVLPGAgHFPPLEQPEAFAAALRDFLARL 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 31-280 4.31e-22

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 92.57  E-value: 4.31e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   31 DAIVFQHGNPTSSYLWRNIMPHLEGLGRLVAC-DLIGMGASDKlsPSGPDRYSYGEQRDFLFALWDALDLgDHVVLVLHD 109
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIAlDLRGFGKSSR--PKAQDDYRTDDLAEDLEYILEALGL-EKVNLVGHS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  110 WGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRspqgepmalehNIFVERVLPGAILRQLSDE--- 186
Cdd:pfam00561  78 MGGLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFPGFF-----------DGFVADFAPNPLGRLVAKLlal 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  187 -EMNHYRRPFVNGGEDRRPTLSWPR--NLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGR-IRDYVRSWP 262
Cdd:pfam00561 147 lLLRLRLLKALPLLNKRFPSGDYALakSLVTGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQaLEKLAQLFP 226

                         250
                  ....*....|....*....
gi 489508497  263 NQTEITVPGV-HFVQEDSP 280
Cdd:pfam00561 227 NARLVVIPDAgHFAFLEGP 245
 
Name Accession Description Interval E-value
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 4-300 5.48e-173

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 480.26  E-value: 5.48e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   4 FGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSgpdrYSY 83
Cdd:PRK03592   1 FGVEPPGEMRRVEVLGSRMAYIETGEGDPIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKPDID----YTF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  84 GEQRDFLFALWDALDLgDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQ-GEP 162
Cdd:PRK03592  77 ADHARYLDAWFDALGL-DDVVLVGHDWGSALGFDWAARHPDRVRGIAFMEAIVRPMTWDDFPPAVRELFQALRSPGeGEE 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 163 MALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNgGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFI 242
Cdd:PRK03592 156 MVLEENVFIERVLPGSILRPLSDEEMAVYRRPFPT-PESRRPTLSWPRELPIDGEPADVVALVEEYAQWLATSDVPKLLI 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489508497 243 NAEPGAII-TGRIRDYVRSWPNQTEITV--PGVHFVQEDSPEEIGAAIAQFVRRLRSAAGV 300
Cdd:PRK03592 235 NAEPGAILtTGAIRDWCRSWPNQLEITVfgAGLHFAQEDSPEEIGAAIAAWLRRLRLAVSA 295
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 12-295 2.56e-37

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 134.33  E-value: 2.56e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  12 PKYLEIAGK-----RMAYIDEGKGDA--IVFQHGNPTSSYLWRNIMPHLEGLG-RLVACDLIGMGASDKlsPSGPDRYSY 83
Cdd:PRK00870  21 PHYVDVDDGdggplRMHYVDEGPADGppVLLLHGEPSWSYLYRKMIPILAAAGhRVIAPDLIGFGRSDK--PTRREDYTY 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  84 GEQRDFLFALWDALDLGDhVVLVLHDWGSALGFDWANQHRDRVQGIAFMEaivTPMTWADWPPAvrGVFQGFRSpqgepM 163
Cdd:PRK00870  99 ARHVEWMRSWFEQLDLTD-VTLVCQDWGGLIGLRLAAEHPDRFARLVVAN---TGLPTGDGPMP--DAFWAWRA-----F 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 164 ALEHNIF-VERVLPGAILRQLSDEEMNHYRRPFVN----GGEDRRPTLswprnLPIDGEPAEVVAlvNEYRsW--LEETD 236
Cdd:PRK00870 168 SQYSPVLpVGRLVNGGTVRDLSDAVRAAYDAPFPDesykAGARAFPLL-----VPTSPDDPAVAA--NRAA-WavLERWD 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489508497 237 MPKL--FINAEPgaiITG----RIRDYVRSWPNQTEITVPGV-HFVQEDSPEEIGAAIAQFVRRLR 295
Cdd:PRK00870 240 KPFLtaFSDSDP---ITGggdaILQKRIPGAAGQPHPTIKGAgHFLQEDSGEELAEAVLEFIRATP 302
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 12-294 1.23e-28

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 109.32  E-value: 1.23e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  12 PKYLEIAGKRMAYIDEG-KGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLspsgPDRYSYGEQRDFL 90
Cdd:COG0596    4 PRFVTVDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKP----AGGYTLDDLADDL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  91 FALWDALDLGDhVVLVLHDWGSALGFDWANQHRDRVQGIAfmeaivtpmtwadwppavrgvfqgfrspqgepmalehnif 170
Cdd:COG0596   80 AALLDALGLER-VVLVGHSMGGMVALELAARHPERVAGLV---------------------------------------- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 171 vervlpgailrqLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDgepaevvalvnEYRSWLEETDMPKLFINAEPGAII 250
Cdd:COG0596  119 ------------LVDEVLAALAEPLRRPGLAPEALAALLRALART-----------DLRERLARITVPTLVIWGEKDPIV 175

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489508497 251 TGRI-RDYVRSWPNQTEITVPGV-HFVQEDSPEEIGAAIAQFVRRL 294
Cdd:COG0596  176 PPALaRRLAELLPNAELVVLPGAgHFPPLEQPEAFAAALRDFLARL 221
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 21-289 9.47e-27

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 106.09  E-value: 9.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  21 RMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGpdrYSYGEQRDFLFALWDALDLG 100
Cdd:PRK03204  25 RIHYIDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFG---YQIDEHARVIGEFVDHLGLD 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 101 DHVVLVlHDWGSALGFDWANQHRDRVQGiafmeaIVTPMTWAdWPP---AVRGVFQGFRSPQGEPMALEHNIFVERVLPG 177
Cdd:PRK03204 102 RYLSMG-QDWGGPISMAVAVERADRVRG------VVLGNTWF-WPAdtlAMKAFSRVMSSPPVQYAILRRNFFVERLIPA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 178 AILRQLSDEEMNHYRrpfvnggeDRRPTLSWPRNLPIdgEPAEVVA---LVNEYRSWLEET--DMPKLFINA------EP 246
Cdd:PRK03204 174 GTEHRPSSAVMAHYR--------AVQPNAAARRGVAE--MPKQILAarpLLARLAREVPATlgTKPTLLVWGmkdvafRP 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 489508497 247 GAIITgRIRdyvRSWPNQTEITVPGV-HFVQEDSPEEIGAAIAQ 289
Cdd:PRK03204 244 KTILP-RLR---ATFPDHVLVELPNAkHFIQEDAPDRIAAAIIE 283
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 31-280 4.31e-22

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 92.57  E-value: 4.31e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   31 DAIVFQHGNPTSSYLWRNIMPHLEGLGRLVAC-DLIGMGASDKlsPSGPDRYSYGEQRDFLFALWDALDLgDHVVLVLHD 109
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIAlDLRGFGKSSR--PKAQDDYRTDDLAEDLEYILEALGL-EKVNLVGHS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  110 WGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRspqgepmalehNIFVERVLPGAILRQLSDE--- 186
Cdd:pfam00561  78 MGGLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFPGFF-----------DGFVADFAPNPLGRLVAKLlal 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  187 -EMNHYRRPFVNGGEDRRPTLSWPR--NLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGR-IRDYVRSWP 262
Cdd:pfam00561 147 lLLRLRLLKALPLLNKRFPSGDYALakSLVTGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQaLEKLAQLFP 226

                         250
                  ....*....|....*....
gi 489508497  263 NQTEITVPGV-HFVQEDSP 280
Cdd:pfam00561 227 NARLVVIPDAgHFAFLEGP 245
PRK05855 PRK05855
SDR family oxidoreductase;
19-113 1.70e-08

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 55.37  E-value: 1.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  19 GKRMAYIDEG--KGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKlsPSGPDRYSYGEQRDFLFALWDA 96
Cdd:PRK05855  12 GVRLAVYEWGdpDRPTVVLVHGYPDNHEVWDGVAPLLADRFRVVAYDVRGAGRSSA--PKRTAAYTLARLADDFAAVIDA 89

                         90
                 ....*....|....*..
gi 489508497  97 LDLGDHVVLVLHDWGSA 113
Cdd:PRK05855  90 VSPDRPVHLLAHDWGSI 106
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 21-287 4.99e-08

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 53.73  E-value: 4.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  21 RMAYIDEGKGD--AIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDALD 98
Cdd:PLN03084 116 RWFCVESGSNNnpPVLLIHGFPSQAYSYRKVLPVLSKNYHAIAFDWLGFGFSDKPQPGYGFNYTLDEYVSSLESLIDELK 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  99 lGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPmTWADWPPAVrGVFQGFrspqgepmaLEHNIFVE---RVL 175
Cdd:PLN03084 196 -SDKVSLVVQGYFSPPVVKYASAHPDKIKKLILLNPPLTK-EHAKLPSTL-SEFSNF---------LLGEIFSQdplRAS 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497 176 PGAILR----QLSDEEMNHYRRPFVNGGedrrpTLSWPRNLPIDGEPAEVVALVNEYRSWLEETD--MPKLFINAEPGAI 249
Cdd:PLN03084 264 DKALTScgpyAMKEDDAMVYRRPYLTSG-----SSGFALNAISRSMKKELKKYIEEMRSILTDKNwkTPITVCWGLRDRW 338

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 489508497 250 ITGR-IRDYVRSWpNQTEITVP-GVHFVQEDSPEEIGAAI 287
Cdd:PLN03084 339 LNYDgVEDFCKSS-QHKLIELPmAGHHVQEDCGEELGGII 377
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
15-132 1.74e-07

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 50.77  E-value: 1.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  15 LEIAGKRMAYIDEGKGdAIVFQHGNPTSSYLWRNIMPHLEGLG-RLVACDLIGMGASDKLspsGPDRYSYGEQRDFLFAL 93
Cdd:COG2267   14 LRLRGRRWRPAGSPRG-TVVLVHGLGEHSGRYAELAEALAAAGyAVLAFDLRGHGRSDGP---RGHVDSFDDYVDDLRAA 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 489508497  94 WDAL--DLGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFM 132
Cdd:COG2267   90 LDALraRPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLL 130
PLN02578 PLN02578
hydrolase
 14-72 2.14e-05

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 45.60  E-value: 2.14e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489508497  14 YLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDK 72
Cdd:PLN02578  70 FWTWRGHKIHYVVQGEGLPIVLIHGFGASAFHWRYNIPELAKKYKVYALDLLGFGWSDK 128
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 28-151 1.30e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 39.72  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  28 GKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKlspsgPDRYSYGEQRDFLFALWdALDLGDHVVLVL 107
Cdd:PLN02824  27 TSGPALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGYGYSDK-----PNPRSAPPNSFYTFETW-GEQLNDFCSDVV 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 489508497 108 HDwgsaLGFDWANQhrdrVQGIAFMEAIVtpmtwaDWPPAVRGV 151
Cdd:PLN02824 101 GD----PAFVICNS----VGGVVGLQAAV------DAPELVRGV 130
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 33-286 1.41e-03

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 39.38  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497   33 IVFQHGNPTSSYLWRnimPHLEGLGRLVACDLIGMGASDklspsgPDRYSYGEQRDFLfALWDALDLGDHVVLVLHDWGS 112
Cdd:pfam12697   1 VVLVHGAGLSAAPLA---ALLAAGVAVLAPDLPGHGSSS------PPPLDLADLADLA-ALLDELGAARPVVLVGHSLGG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  113 ALGFDWAnqHRDRVQGIaFMEAIVTPmtwADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPgailrqlsDEEMNHYR 192
Cdd:pfam12697  71 AVALAAA--AAALVVGV-LVAPLAAP---PGLLAALLALLARLGAALAAPAWLAAESLARGFLD--------DLPADAEW 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489508497  193 RPFVNGGEDRRPTLSWPRNLPIDGEPAEVValvneyrsWLEETDMpklfinaepgaIITGRIRDYVRSWPNQTEITVPGV 272
Cdd:pfam12697 137 AAALARLAALLAALALLPLAAWRDLPVPVL--------VLAEEDR-----------LVPELAQRLLAALAGARLVVLPGA 197

                         250
                  ....*....|....*
gi 489508497  273 -HFVQEDsPEEIGAA 286
Cdd:pfam12697 198 gHLPLDD-PEEVAEA 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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