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Conserved domains on  [gi|489525972|ref|WP_003430728|]
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toxic anion resistance protein [Clostridioides difficile]

Protein Classification

toxic anion resistance protein( domain architecture ID 10530726)

toxic anion resistance protein similar to Escherichia coli protein TelA (or KlaB), which is associated with cryptic tellurite resistance

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TelA pfam05816
Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like ...
55-381 4.73e-156

Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.


:

Pssm-ID: 461748  Cd Length: 330  Bit Score: 442.34  E-value: 4.73e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972   55 KEFAEKIDITNTNMILQYGAGAQKKVAGFSETALKSVKTRDLGEVGDMLTNLVTDLKAFSAD---EKEQSGFLGIFKKAN 131
Cdd:pfam05816   1 EEFAKKIDITNSNSILQYGAEAQKKIADFSDRMLDNVRTKDLGEVGDLLNELRRTLKDFDPDelgEEKKLGFLPLFKKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  132 NKISNLKTKYDSAEVNVDKVSKELQKHQVKILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARL 211
Cdd:pfam05816  81 NKIEKYFAKYQTAGAQIDKIVVELEKGQDELLKDNAMLDQMYEKNLEYFKELEKYIAAGELKLEELDAELLPELEAKAAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  212 SGSTEDAQSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPLWKNQIVLALGISHLN 291
Cdd:pfam05816 161 SGDPEDAQALRDLRQALFRLEQRIHDLELQRAVSIQTAPQIRLVQNNNQELIEKIQSAITTTIPLWKNQLVVALALKRQK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  292 QAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDIDTIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKI 371
Cdd:pfam05816 241 LALEAQKAVNDTTNELLLKNAEMLKTQSIETAKEAERGIVDIETLKKTNQTLIATIDETLQIQEEGREKRREAEAELEQL 320
                         330
                  ....*....|
gi 489525972  372 ENELKSKLLE 381
Cdd:pfam05816 321 EEELKQKLLR 330
 
Name Accession Description Interval E-value
TelA pfam05816
Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like ...
55-381 4.73e-156

Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.


Pssm-ID: 461748  Cd Length: 330  Bit Score: 442.34  E-value: 4.73e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972   55 KEFAEKIDITNTNMILQYGAGAQKKVAGFSETALKSVKTRDLGEVGDMLTNLVTDLKAFSAD---EKEQSGFLGIFKKAN 131
Cdd:pfam05816   1 EEFAKKIDITNSNSILQYGAEAQKKIADFSDRMLDNVRTKDLGEVGDLLNELRRTLKDFDPDelgEEKKLGFLPLFKKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  132 NKISNLKTKYDSAEVNVDKVSKELQKHQVKILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARL 211
Cdd:pfam05816  81 NKIEKYFAKYQTAGAQIDKIVVELEKGQDELLKDNAMLDQMYEKNLEYFKELEKYIAAGELKLEELDAELLPELEAKAAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  212 SGSTEDAQSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPLWKNQIVLALGISHLN 291
Cdd:pfam05816 161 SGDPEDAQALRDLRQALFRLEQRIHDLELQRAVSIQTAPQIRLVQNNNQELIEKIQSAITTTIPLWKNQLVVALALKRQK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  292 QAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDIDTIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKI 371
Cdd:pfam05816 241 LALEAQKAVNDTTNELLLKNAEMLKTQSIETAKEAERGIVDIETLKKTNQTLIATIDETLQIQEEGREKRREAEAELEQL 320
                         330
                  ....*....|
gi 489525972  372 ENELKSKLLE 381
Cdd:pfam05816 321 EEELKQKLLR 330
YaaN COG3853
Uncharacterized conserved protein YaaN involved in tellurite resistance [Defense mechanisms];
13-381 1.05e-148

Uncharacterized conserved protein YaaN involved in tellurite resistance [Defense mechanisms];


Pssm-ID: 443062  Cd Length: 389  Bit Score: 425.85  E-value: 1.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  13 LTLDPFGEESNTndiDNSDLLMKKDEKDPEEEKLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVAGFSETALKSVK 92
Cdd:COG3853   17 LLAPPAPVPEVP---EQAAGMVDPEEAEVDLSKLSAEADAFVEALAAQIDLSDVNAILQYGAKAQRKLAAFSNRMLDRVK 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  93 TRDLGEVGDMLTNLVTDLKAFSADEKEQ---SGFLG-IFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQVKILKDIAM 168
Cdd:COG3853   94 TKDLGEVGDSLSELRRTLEDLDPSELDDlkkKGLLGkLFPKGGNKLEKYFAKYQSAQTQIDKISVALEKGQDELLKDNAM 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972 169 LDKMYELNLAYSKELTMYIIAGKQKLKDMKEyEMPKLREKARLSGSTEDAQSVNDMVSLCDRFEKKIHDLELTRMVSLQM 248
Cdd:COG3853  174 LDQLYEKNWEYFKELNQYIAAGELKLEELEA-KIPALAAEAEASGDPEDAQALNDLEQVLFRLEQRVHDLLLQRAVSIQG 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972 249 APQIRLVQNSNNLMAEKIQSTIVNTIPLWKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESER 328
Cdd:COG3853  253 APQIRLVQKNNQELIEKIQSAITTTIPLWKNQVAVALALARQKLALDAQKAVNDTTNELLLKNAEMLKQNSIEIAKEAER 332
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489525972 329 GIVDIDTIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLE 381
Cdd:COG3853  333 GVVDIETLKQAFENLIATIDETLQIQDEGRAKRAQAEQELERLEEELKQYLLR 385
 
Name Accession Description Interval E-value
TelA pfam05816
Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like ...
55-381 4.73e-156

Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.


Pssm-ID: 461748  Cd Length: 330  Bit Score: 442.34  E-value: 4.73e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972   55 KEFAEKIDITNTNMILQYGAGAQKKVAGFSETALKSVKTRDLGEVGDMLTNLVTDLKAFSAD---EKEQSGFLGIFKKAN 131
Cdd:pfam05816   1 EEFAKKIDITNSNSILQYGAEAQKKIADFSDRMLDNVRTKDLGEVGDLLNELRRTLKDFDPDelgEEKKLGFLPLFKKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  132 NKISNLKTKYDSAEVNVDKVSKELQKHQVKILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARL 211
Cdd:pfam05816  81 NKIEKYFAKYQTAGAQIDKIVVELEKGQDELLKDNAMLDQMYEKNLEYFKELEKYIAAGELKLEELDAELLPELEAKAAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  212 SGSTEDAQSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPLWKNQIVLALGISHLN 291
Cdd:pfam05816 161 SGDPEDAQALRDLRQALFRLEQRIHDLELQRAVSIQTAPQIRLVQNNNQELIEKIQSAITTTIPLWKNQLVVALALKRQK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  292 QAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDIDTIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKI 371
Cdd:pfam05816 241 LALEAQKAVNDTTNELLLKNAEMLKTQSIETAKEAERGIVDIETLKKTNQTLIATIDETLQIQEEGREKRREAEAELEQL 320
                         330
                  ....*....|
gi 489525972  372 ENELKSKLLE 381
Cdd:pfam05816 321 EEELKQKLLR 330
YaaN COG3853
Uncharacterized conserved protein YaaN involved in tellurite resistance [Defense mechanisms];
13-381 1.05e-148

Uncharacterized conserved protein YaaN involved in tellurite resistance [Defense mechanisms];


Pssm-ID: 443062  Cd Length: 389  Bit Score: 425.85  E-value: 1.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  13 LTLDPFGEESNTndiDNSDLLMKKDEKDPEEEKLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVAGFSETALKSVK 92
Cdd:COG3853   17 LLAPPAPVPEVP---EQAAGMVDPEEAEVDLSKLSAEADAFVEALAAQIDLSDVNAILQYGAKAQRKLAAFSNRMLDRVK 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972  93 TRDLGEVGDMLTNLVTDLKAFSADEKEQ---SGFLG-IFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQVKILKDIAM 168
Cdd:COG3853   94 TKDLGEVGDSLSELRRTLEDLDPSELDDlkkKGLLGkLFPKGGNKLEKYFAKYQSAQTQIDKISVALEKGQDELLKDNAM 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972 169 LDKMYELNLAYSKELTMYIIAGKQKLKDMKEyEMPKLREKARLSGSTEDAQSVNDMVSLCDRFEKKIHDLELTRMVSLQM 248
Cdd:COG3853  174 LDQLYEKNWEYFKELNQYIAAGELKLEELEA-KIPALAAEAEASGDPEDAQALNDLEQVLFRLEQRVHDLLLQRAVSIQG 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489525972 249 APQIRLVQNSNNLMAEKIQSTIVNTIPLWKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESER 328
Cdd:COG3853  253 APQIRLVQKNNQELIEKIQSAITTTIPLWKNQVAVALALARQKLALDAQKAVNDTTNELLLKNAEMLKQNSIEIAKEAER 332
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489525972 329 GIVDIDTIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLE 381
Cdd:COG3853  333 GVVDIETLKQAFENLIATIDETLQIQDEGRAKRAQAEQELERLEEELKQYLLR 385
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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