|
Name |
Accession |
Description |
Interval |
E-value |
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
7-383 |
1.69e-158 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 450.66 E-value: 1.69e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 7 QDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEELCMTW--GYVYTRECNPTLTELEAKLAMLENAESAISST 84
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEegGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 85 SGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLV 164
Cdd:COG0626 81 SGMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 165 DIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVRWPSLCCfTGASL 244
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNA-LGAVL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 245 PPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDGInglt 324
Cdd:COG0626 240 SPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSG-FGGMLSFELKGGR---- 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489530182 325 rdQASRRLMNSLELATIATSLGEEHTLVQ---------MNGE---------NLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:COG0626 315 --EAARRFLDALKLFTLAVSLGGVESLIThpatmthrsLPPEeraalgitdGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
25-381 |
3.25e-144 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 413.52 E-value: 3.25e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 25 GALATPICQTATFAAKTVEHFEELC--MTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD 102
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADLFalREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 103 HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIV 182
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 183 DSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGS-KELIDLVRWPSLccFTGASLPPMSAWMILRGMKTLDM 261
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSgEALIQRLRFLRL--ALGTILSPFDAWLLLRGLKTLPL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 262 RMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDGingltrDQASRRLMNSLELATI 341
Cdd:cd00614 239 RMERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSG-YGGVFSFELKGG------LEAAKKFLNALKLFSL 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 489530182 342 ATSLGEEHTLVQMNG------------------ENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:cd00614 312 AVSLGGVESLVEHPAsmthsqlppeeraaagitPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
1-384 |
4.49e-139 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 401.90 E-value: 4.49e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH------FEELcmtwGYVYTRECNPTLTELEAKLAML 74
Cdd:PRK06234 1 MENIKKMGFATKAIHGGHIGDKQFGSLATPIYQTSTFIFDSAEQggrrfaGEES----GYIYSRLGNPTSTEVENKLALL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 75 ENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIE 154
Cdd:PRK06234 77 EGGEAAVVAASGMGAISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 155 SPLNPSLDLVDIKTIAEIAHENKS--LAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVR 232
Cdd:PRK06234 157 TPANPTLKVTDIKAISNIAHENNKecLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 233 WPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNgLGGGVV 312
Cdd:PRK06234 237 LFGIKDMTGSVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMS-LPGAMI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 313 SFKLKDGIngltrdQASRRLMNSLELATIATSLGEEHTLVQ----MN--------------GENLIRIAVGLESSNDIIN 374
Cdd:PRK06234 316 SFELKGGV------EEGKVVMNNVKLATLAVSLGDAETLIQhpasMThspytaeerkeagiSDGLVRLSVGLEDVDDIIA 389
|
410
....*....|
gi 489530182 375 DFKQAIEKLK 384
Cdd:PRK06234 390 DLKQALDLIV 399
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
10-381 |
5.88e-134 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 387.74 E-value: 5.88e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 10 ETKIIHWGHSADPTTGALATPICQTATFAAKTV-EHFeelcmtwGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAgEEG-------GYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:pfam01053 74 AITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVA-GSKELIDLVRWPSLCcfTGASLPPM 247
Cdd:pfam01053 154 IAKLAKKHGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVvNGEELGKELYFLQNA--TGAVLSPF 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 248 SAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDGIngltrdQ 327
Cdd:pfam01053 232 DAWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKG-FGGMLSFELKGGL------E 304
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 328 ASRRLMNSLELATIATSLGEEHTLVQMN------------------GENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:pfam01053 305 AAKKFLDNLKLFSLAVSLGGVESLISHPatmthasippeereaagiTDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
1-384 |
8.88e-127 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 371.28 E-value: 8.88e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNiNQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH------FEELcmtwGYVYTRECNPTLTELEAKLAML 74
Cdd:COG2873 1 MTEK-KYGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDDAEHaadlfaLKEP----GNIYTRIMNPTTDVLEKRIAAL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 75 ENAESAISSTSGMGAITSTILALVKSGDHIVSSDGI-------FSHTklfmselLSKFGVEVTFVDAVNPQNVKEAMRPN 147
Cdd:COG2873 76 EGGVAALATASGQAAITLAILNLAEAGDHIVASSSLyggtynlFAHT-------LPRLGIEVRFVDPDDPEAFEAAIDPN 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 148 TKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV------ 221
Cdd:COG2873 149 TKAIFGETIGNPALDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIvdggnf 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 222 --AGSKelidlvRWPSLC------------------CF-----------TGASLPPMSAWMILRGMKTLDMRMKKHCENG 270
Cdd:COG2873 229 dwAANG------KFPELTepdpsyhglvyteafgnaAFitkarvqllrdLGAALSPFNAFLLLQGLETLSLRMERHVENA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 271 LAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGIngltrdQASRRLMNSLELATIATSLGEEHT 350
Cdd:COG2873 303 LKVAEFLEAHPKVAWVNYPGLPSHPYHELAQKYLPKGAGGVLTFGLKGGR------EAGKKFIDSLKLFSHLANIGDAKS 376
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 489530182 351 LV---------QMN---------GENLIRIAVGLESSNDIINDFKQAIEKLK 384
Cdd:COG2873 377 LVihpastthsQLSeeeqaaagvTPDLIRLSVGIEDIDDIIADLDQALAAAT 428
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
1-384 |
1.67e-113 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 336.77 E-value: 1.67e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNINQD-LETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEElCMTW---GYVYTRECNPTLTELEAKLAMLEN 76
Cdd:PRK07503 1 MRDSHNNTgFSTRAIHHGYDPLDHGGALVPPVYLTATFAFPTAEYGAE-CFAGeeeGHFYSRISNPTLALLEQRMASLEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 77 AESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESP 156
Cdd:PRK07503 80 GEAAVALASGMGAITATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 157 LNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVRWPSL 236
Cdd:PRK07503 160 ANPNMRLVDIAAVAEIAHGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIRLEGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 237 CCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNgLGGGVVSFKL 316
Cdd:PRK07503 240 KDMTGAVMSPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMA-LPGGMIAFEL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 317 KDGIngltrdQASRRLMNSLELATIATSLGEEHTLVQ----MN--------------GENLIRIAVGLESSNDIINDFKQ 378
Cdd:PRK07503 319 KGGI------AAGRRFMNALQLFARAVSLGDAESLAQhpasMThstytpeeraehgiSEGLVRLSVGLEDVADILADLAQ 392
|
....*.
gi 489530182 379 AIEKLK 384
Cdd:PRK07503 393 ALDACA 398
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
53-375 |
1.12e-112 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 334.28 E-value: 1.12e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 53 GYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFV 132
Cdd:PRK08133 52 GNIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAILAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFV 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 133 DAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFING 212
Cdd:PRK08133 132 DLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 213 HGDTLGGAVAGSKELIDLVrWPSLCCfTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALK 292
Cdd:PRK08133 212 QGRVLGGAVVGSKELMEEV-FGFLRT-AGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLP 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 293 SHPQYELCKTQMNGlGGGVVSFKLKDGingltRDQAsRRLMNSLELATIATSLGEEHTLVQMN----------------- 355
Cdd:PRK08133 290 SHPQHELAKRQQKG-GGAIVSFEVKGG-----REAA-WRVIDATRLISITANLGDTKTTITHPattthgrlspearaaag 362
|
330 340
....*....|....*....|.
gi 489530182 356 -GENLIRIAVGLESSNDIIND 375
Cdd:PRK08133 363 iTEGLIRVAVGLEDVADIKAD 383
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
9-381 |
1.72e-108 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 324.70 E-value: 1.72e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTGALATPICQTATFAAKTVEH------FEELcmtwGYVYTRECNPTLTELEAKLAMLENAESAIS 82
Cdd:TIGR01326 2 FETLQLHAGQEPDPTTGSRAVPIYQTTSYVFDSTEHaaalfgLQEP----GNIYSRLMNPTTDVLEQRIAALEGGVAALA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 83 STSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLD 162
Cdd:TIGR01326 78 VASGQAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQIN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 163 LVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELiDLV--RWPSLC--- 237
Cdd:TIGR01326 158 VLDIEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDGGKF-DWNngRFPLFTtpd 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 238 ---------------CF-----------TGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPAL 291
Cdd:TIGR01326 237 psyhglvftetlgnpAFilkarvqllrdLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 292 KSHPQYELCKTQMNGLGGGVVSFKLKDGINgltrdqASRRLMNSLELATIATSLGEEHTLV---------QMNGE----- 357
Cdd:TIGR01326 317 ASHPHHALAKKYLPKGFGAVLSFEIKGGRE------AGKKFIDALKLASHLANVGDAKSLVihpastthsQLSEEeqlka 390
|
410 420
....*....|....*....|....*...
gi 489530182 358 ----NLIRIAVGLESSNDIINDFKQAIE 381
Cdd:TIGR01326 391 gvtpGLIRLSVGIENIDDIIADLEQALE 418
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
1-382 |
1.04e-107 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 321.59 E-value: 1.04e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHfeelcMTWGYVYTRECNPTLTELEAKLAMLENAESA 80
Cdd:PRK07811 5 SDHHANQGFATRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGG-----LRGGYEYARTGNPTRTALEEQLAALEGGAYG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 81 ISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS 160
Cdd:PRK07811 80 RAFSSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 161 LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGA-VAGSKELIDLVRWpsLCCF 239
Cdd:PRK07811 160 LSITDIAALAELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGAlVTNDEELDEAFAF--LQNG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 240 TGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDG 319
Cdd:PRK07811 238 AGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGF-GGMVSVRLAGG 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489530182 320 ingltrDQASRRLMNSLELATIATSLGEEHTLVQMNGE---------------NLIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK07811 317 ------EEAARDFCARTKVFTLAESLGGVESLIEHPSAmthastagsqlevpdDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
11-384 |
1.63e-106 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 318.99 E-value: 1.63e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 11 TKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEELCM--TWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PRK08249 11 TKAVWAGEKEYLPYGATQVPVVLSVAYGYDDIDEWYDVALgkKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:PRK08249 91 AISNTLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIER 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVRwpSLCCFTGASLPPMS 248
Cdd:PRK08249 171 LAAAAKKVGALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVY--HYREINGATMDPMS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 249 AWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDGINgltrdqA 328
Cdd:PRK08249 249 AYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGF-GGILSFVLKGGMD------T 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489530182 329 SRRLMNSLELATIATSLGEEHTLV-----------------QMN-GENLIRIAVGLESSNDIINDFKQAIEKLK 384
Cdd:PRK08249 322 VKRLLPKLRYAHRAANLGAVETIYgparttshventleeraALGiPEGLVRISVGIEDTEDLIADLEQAFAHLE 395
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
7-383 |
1.68e-98 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 297.91 E-value: 1.68e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 7 QDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEE--LCMTWGYVYTRECNPTLTELEAKLAMLENAESAISST 84
Cdd:PRK06767 4 KHMETALIHHGYTSEEHKGSLTPPLFQTSTFTFETAQQGEAsfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 85 SGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLV 164
Cdd:PRK06767 84 SGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 165 DIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVRWPSLCCFtGASL 244
Cdd:PRK06767 164 DLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDI-GGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 245 PPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEeenvelvkYPALKS--HPQYELCKTQMNgLGGGVVSFKLKDGing 322
Cdd:PRK06767 243 APFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKN--------HDAVEGvwYPEGELASRQMK-RGGGVISFSIKGG--- 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489530182 323 ltrDQASRRLMNSLELATIATSLGEEHTLVQMNG------------------ENLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK06767 311 ---KEETQAFINDLHFITIAVSLGDTETLIQHPAtmthaaipaelrqemgiyDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
10-381 |
1.28e-95 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 290.09 E-value: 1.28e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 10 ETKIIHWGHSADPTTGALATPICQTATFAAKTV-EHfeelcmtWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PRK07671 4 KTKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVgKH-------QGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AITStILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:PRK07671 77 AITA-VMMLFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGG-AVAGSKELIDLVRWpsLCCFTGASLPPM 247
Cdd:PRK07671 156 ISTIAKEKGLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGlVVVNSPELAEDLHF--VQNSTGGILGPQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 248 SAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDGingltrdQ 327
Cdd:PRK07671 234 DSWLLLRGLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGF-GGMISFDVGSE-------E 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 328 ASRRLMNSLELATIATSLGEEHTLVQMNG------------------ENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:PRK07671 306 TANKVLERLQYFTLAESLGAVESLISIPSqmthasipadrrkelgitDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
6-384 |
2.02e-93 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 285.13 E-value: 2.02e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 6 NQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEElcmtwgYVYTRECNPTLTELEAKLAMLENAESAISSTS 85
Cdd:PRK08064 4 SYSIDTLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGK------YDYSRSGNPTREALEDIIAELEGGTKGFAFAS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 86 GMGAITSTILALVKsGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVD 165
Cdd:PRK08064 78 GMAAISTAFLLLSK-GDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 166 IKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGG-AVAGSKELIDLVRwpSLCCFTGASL 244
Cdd:PRK08064 157 IRGVVKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGlAVVKDEELAQKLY--FLQNSFGAVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 245 PPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDginglt 324
Cdd:PRK08064 235 GVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATS-AGAVLSFTLQS------ 307
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489530182 325 rDQASRRLMNSLELATIATSLG------------------EEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK 384
Cdd:PRK08064 308 -EEAVRQFVSHVKLPVFAVSLGavesilsypakmshaampKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVE 384
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
53-384 |
1.65e-90 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 277.79 E-value: 1.65e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 53 GYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFV 132
Cdd:PRK07504 56 GFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLV 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 133 DAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFING 212
Cdd:PRK07504 136 DGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDG 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 213 HGDTLGGAVAGSKELI-----DLVRwpslccFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVK 287
Cdd:PRK07504 216 QGRCLGGVVLSDKAWIeehlqDYFR------HTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVI 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 288 YPALKSHPQYELCKTQMNGlGGGVVSFKLKDGingltrDQASRRLMNSLELATIATSLGEEHTLVQMN------------ 355
Cdd:PRK07504 290 YPGRADHPQADIIAKQMTG-GSTLVAFELKGG------KEAAFRFLNALKIVRISNNLGDAKSLITHPattthknlspea 362
|
330 340 350
....*....|....*....|....*....|....*
gi 489530182 356 ------GENLIRIAVGLESSNDIINDFKQAIEKLK 384
Cdd:PRK07504 363 raelgiSEGFLRLSAGLEDTDDLIEDLAAALKKVR 397
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
10-380 |
2.43e-89 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 275.85 E-value: 2.43e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 10 ETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGM 87
Cdd:PRK08134 10 DTLALHAGAAPDPATGARAVPIHLTTSFVFRDSDHAAALfnLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 88 GAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIK 167
Cdd:PRK08134 90 AALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 168 TIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV--AGSKELIDLVRWPSLC-------- 237
Cdd:PRK08134 170 TVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLvdGGRFDWEASGKFPELTepyagfhg 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 238 -CFT--------------------GASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQ 296
Cdd:PRK08134 250 mVFAeestvaafllrarreglrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHPD 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 297 YELCKTQMNGLGGGVVSFKLKDGingltrDQASRRLMNSLELATIATSLGEEHTLV---------QMN---------GEN 358
Cdd:PRK08134 330 HALAKRLLPRGAGSVFSFDLKGG------RAAGRKFIESLKLFSHLANVGDARSLVihpastthfRMDaaalaaagiGEG 403
|
410 420
....*....|....*....|..
gi 489530182 359 LIRIAVGLESSNDIINDFKQAI 380
Cdd:PRK08134 404 TIRLSIGLEDADDLIDDLKRAL 425
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
1-382 |
1.77e-87 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 271.33 E-value: 1.77e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAE 78
Cdd:PRK08248 1 MSEERTFRLETLAIHAGQEIDPTTGSRAVPIYQTTSYGFRDSEHAANLfsLKEFGNIYTRIMNPTTDVFEKRIAALEGGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 79 SAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLN 158
Cdd:PRK08248 81 GALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 159 PSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV--AGSKELIDLVRWPSL 236
Cdd:PRK08248 161 PKGDVLDIEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIvdSGKFDWKGSGKFPGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 237 C---------CFT--------------------GASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVK 287
Cdd:PRK08248 241 TepdpsyhglVYTdavgeaayitkarvqllrdlGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 288 YPALKSHPQYELCKTQMNGLGGGVVSFKLKDGIngltrdQASRRLMNSLELATIATSLGEEHTLV---------QMNGEN 358
Cdd:PRK08248 321 YPGLPSHPSYELAKKYLPKGQGAILTFGIKGGV------EAGKKLIDSVKLFSHLANVGDSKSLIihpastthqQLSEEE 394
|
410 420 430
....*....|....*....|....*....|...
gi 489530182 359 ---------LIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK08248 395 qlaagvtpgLVRLSVGTEAIDDILDDLRQAIRQ 427
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
1-382 |
1.03e-86 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 267.72 E-value: 1.03e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNINQDLETKIIHWgHSADPTTGALATPICQTATFaakTVEHFEELCMTWG-----YVYTRECNPTLTELEAKLAMLE 75
Cdd:PRK05968 1 MNDGLDPFDLAALITA-HDEGNAFDAVVPPIFQTSLF---TFDSYDEMEDVYAgekvrPIYSRGDNPTVRAFEEMLAKLE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 76 NAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMrPNTKIVYIES 155
Cdd:PRK05968 77 GAEDARGFASGMAAISSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLES 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 156 PLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKELIDLVRWPS 235
Cdd:PRK05968 156 PTSWVFELQDVAALAALAKRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARINAEA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 236 LcCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPqyelcKTQMNGLgGGVVSFK 315
Cdd:PRK05968 236 Y-PYLGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHP-----PAGLSGT-SGLFSFI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 316 LKDGINgltrdqaSRRLMNSLELATIATSLGEEHTLV-----------QMN-------GENLIRIAVGLESSNDIINDFK 377
Cdd:PRK05968 309 FREGID-------VRAFADALKLFRLGVSWGGHESLVvpaevvlqqkaQPNsaarfgvSPRSVRLHVGLEGTEALWADLE 381
|
....*
gi 489530182 378 QAIEK 382
Cdd:PRK05968 382 QALAA 386
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
25-381 |
1.07e-86 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 268.09 E-value: 1.07e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 25 GALATPICQTATFAAKTVEhfeELCMTW-----GYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVK 99
Cdd:PRK05939 8 GAVHKPIHTSVTYGYEDAR---DLIDVFqgkkpGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 100 SGDHIVSSDGIFSHTK-LFMSelLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKS 178
Cdd:PRK05939 85 AGDHLVSSQFLFGNTNsLFGT--LRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 179 LAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKeLIDLVRWPSLccF------------------- 239
Cdd:PRK05939 163 LYVVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTDTG-LFDWSAYPNI--Fpayrkgdpqqwgltqirkk 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 240 ----TGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFK 315
Cdd:PRK05939 240 glrdMGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRH-YGGLLSFE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 316 LKDGINGLTrdqasrrLMNSLELATIATSLGEEHTLV-----------------QMN-GENLIRIAVGLESSNDIINDFK 377
Cdd:PRK05939 319 LADGIDCFD-------FLNRLKLVIKATHLGDTRTLVipvaptiyyemgaerraSMGiADSLIRVSVGIEDEADLIADFE 391
|
....
gi 489530182 378 QAIE 381
Cdd:PRK05939 392 QALD 395
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
21-383 |
2.53e-86 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 266.31 E-value: 2.53e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 21 DPTTGALATPICQTATFAAKTVEHFEelcmtwgyvYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKS 100
Cdd:PRK06460 13 DEATGAITTPIYQTTAYHYPEGEKYR---------YSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 101 GDHIVSSDGIFSHTKLFMSELLSKFGVEVtfvDAVNPQN---VKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENK 177
Cdd:PRK06460 84 GNSVLVHRDMFGRSYRFFTDYLKNWGVNV---DASNPGSdniIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 178 SLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKEL---IDLVRwPSLccftGASLPPMSAWMILR 254
Cdd:PRK06460 161 SILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLlnvIDQMR-RTL----GTSLDPHAAYLTLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 255 GMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDGINgltrdqASRRLMN 334
Cdd:PRK06460 236 GIKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGF-GGVLSFEVNGGQE------SALKVMK 308
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489530182 335 SLELATIATSLG-------------------EEHTLVQMnGENLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK06460 309 SLKLIIPAQTLGgvnsvishpatmshrtlslEERKIVGI-TDSLLRLSVGIEDVNDLIEDLDRALSTL 375
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
25-381 |
4.65e-85 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 263.46 E-value: 4.65e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 25 GALATPICQTATF-----AAKTVEHFEelcmtwgYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVK 99
Cdd:PRK08574 18 GSLQPPIYLTALFrqegeAYPSDRGFD-------LKYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAISTLFFSLLK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 100 SGDHIVSSDGIFSHTkLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSL 179
Cdd:PRK08574 91 AGDRVVLPMEAYGTT-LRLLKSLEKFGVKVVLAYPSTEDIIEAIKEGRTKLVFIETMTNPTLKVIDVPEVAKAAKELGAI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 180 AIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGG-AVAGSKELI-DLVRWPSLccfTGASLPPMSAWMILRGMK 257
Cdd:PRK08574 170 LVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGvAVAWSGEFLeELWEWRRR---LGTIMQPFEAYLVLRGLK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 258 TLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMN-GLGGGVVSFKLKDGingltRDQAsRRLMNSL 336
Cdd:PRK08574 247 TLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGkDLYGGVVSFRVKGG-----RDAV-LKFLRSL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489530182 337 ELATIATSLGEEHTLV----------------QMNG--ENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:PRK08574 321 KLIKPSPSLGGVESLAtypvksaaspipeedrKALGitEDLVRLSVGLEDVEDLIEDLDQALG 383
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
54-380 |
7.06e-85 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 263.52 E-value: 7.06e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 54 YVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVD 133
Cdd:PRK07810 62 FVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVD 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 134 AVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGH 213
Cdd:PRK07810 142 GEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQ 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 214 GDTLGGAVAGSKELID-----LVRwpslccFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKY 288
Cdd:PRK07810 222 GRVLGGAILGDREYIDgpvqkLMR------HTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRY 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 289 PALKSHPQYELCKTQMNGlGGGVVSFKLKDginglTRDQASRR---LMNSLELATIATSLGEEHTLV---------QMN- 355
Cdd:PRK07810 296 PFLPSHPQYDLAKRQMSG-GGTVVTFELDA-----PEDAAKKRafeVLDKLRVIDISNNLGDAKSLIthpattthrAMGp 369
|
330 340 350
....*....|....*....|....*....|...
gi 489530182 356 --------GENLIRIAVGLESSNDIINDFKQAI 380
Cdd:PRK07810 370 egraaiglGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
9-380 |
7.45e-84 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 260.15 E-value: 7.45e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTtGALATPICQTATFAAKTVEHFEElcmtwgYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:TIGR01329 1 LSTLLVNTDNKNDPY-DASSMPIYQTATFKQPLAIENGP------YDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AItSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:TIGR01329 74 AL-DVITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVA-GSKELIDLVRWpsLCCFTGASLPPM 247
Cdd:TIGR01329 153 ISEMAHAQNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAvKGEEIAKKVYF--LQNSTGSGLAPF 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 248 SAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKlkdginglTRDQ 327
Cdd:TIGR01329 231 DCWLLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKG-AGSVLSFE--------TGSV 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 328 A-SRRLMNSLELATIATSLGEEHTLVQMN------------------GENLIRIAVGLESSNDIINDFKQAI 380
Cdd:TIGR01329 302 AlSKRLVEATKLFSITVSFGSVNSLISMPcfmshasipaevreerglPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
9-383 |
2.58e-81 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 253.67 E-value: 2.58e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEElcmtwgYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PRK06176 3 MQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRPKG------YEYSRSGNPTRFALEELIADLEGGVKGFAFASGLA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AITStILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:PRK06176 77 GIHA-VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELIDLVRWpsLCCFTGASLPPM 247
Cdd:PRK06176 156 CASVAKDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVtTNNEALAQEIAF--FQNAIGGVLGPQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 248 SAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDgingltrDQ 327
Cdd:PRK06176 234 DSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGF-SGMLSFTLKN-------DS 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489530182 328 ASRRLMNSLELATIATSLGEEHTLVQMNG------------------ENLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK06176 306 EAVAFVESLKLFILGESLGGVESLVGIPAfmthacipkeqreaagirDGLVRLSVGIEHEQDLLEDLEQAFAKI 379
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
10-375 |
3.69e-81 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 255.06 E-value: 3.69e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 10 ETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGM 87
Cdd:PRK07812 15 ETKQIHAGQTPDPATNARALPIYQTTSYTFDDTDHAAALfgLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 88 GAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDavNPQNV---KEAMRPNTKIVYIESPLNPSLDLV 164
Cdd:PRK07812 95 AAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVE--DPDDLdawRAAVRPNTKAFFAETISNPQIDVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 165 DIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV--AGSKELID------------- 229
Cdd:PRK07812 173 DIPGVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIvdGGTFDWTQgrfpgfttpdpsy 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 230 --LVRWP------------SLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHP 295
Cdd:PRK07812 253 hgVVFAElgppayalkarvQLLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSP 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 296 QYELCKTQMNGLGGGVVSFKLKDGIngltrdQASRRLMNSLELATIATSLGEEHTLV---------QMNGE--------- 357
Cdd:PRK07812 333 WYERAKRLAPKGTGAVLSFELAGGV------EAGKAFVNALTLHSHVANIGDVRSLVihpastthsQLTPEeqlatgvtp 406
|
410
....*....|....*...
gi 489530182 358 NLIRIAVGLESSNDIIND 375
Cdd:PRK07812 407 GLVRLAVGIEGIDDILAD 424
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
9-384 |
1.17e-79 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 250.97 E-value: 1.17e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSG 86
Cdd:PRK06084 3 LETLAIHAGYSPDPTTKAVAVPIYQTTSYAFDDTQHGADLfdLKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 87 MGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDI 166
Cdd:PRK06084 83 MAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 167 KTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGS--------KELIDLVRWPSLC- 237
Cdd:PRK06084 163 QALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVDSgkfpwaehKERFALLNTPDPSy 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 238 -----------------CF------TGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSH 294
Cdd:PRK06084 243 hgvtyteafgpaafigrCRvvplrnMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPDH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 295 PQYELCKTQMNGLGGGVVSFKLKDGingltrDQASRRLMNSLELATIATSLGEEHTLV---------QMNGE-------- 357
Cdd:PRK06084 323 PEHELARRYMGGKPASILSFGIKGG------QAAGARFIDALKLVVRLVNIGDAKSLAchpastthrQLNDEelekagvs 396
|
410 420
....*....|....*....|....*...
gi 489530182 358 -NLIRIAVGLESSNDIINDFKQAIEKLK 384
Cdd:PRK06084 397 rDMVRLSIGIEHIDDIIADLAQALDASK 424
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
54-380 |
3.92e-79 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 247.60 E-value: 3.92e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 54 YVYTRECNPTLTELEAKLAMLENAEsAISSTSGMGAITSTILALVKSGDH-IVSSDGIFShTKLFMSELLSKFGVEVTFV 132
Cdd:PRK07582 43 DTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAITAVLRALLRPGDTvVVPADGYYQ-VRALAREYLAPLGVTVREA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 133 DAVNPQnvkEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFING 212
Cdd:PRK07582 121 PTAGMA---EAALAGADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTG 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 213 HGDTLGGAVAGSK-ELIDLV-RWPSLccfTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPA 290
Cdd:PRK07582 198 HSDLLLGYVAGRDpELMAAVeRWRLL---AGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPG 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 291 LKSHPQYELCKTQMNGLgGGVVSFKLKDGingltrdQASRRLMNSLELATIATSLGEEHTLVQMNG-------ENLIRIA 363
Cdd:PRK07582 275 LPGDPAHEVAARQMRRF-GGLVSFELADA-------AAAERFVAASRLVVAATSFGGVHTSADRRArwgdavpEGFVRLS 346
|
330
....*....|....*..
gi 489530182 364 VGLESSNDIINDFKQAI 380
Cdd:PRK07582 347 CGIEDTDDLVADLERAL 363
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
6-384 |
9.93e-79 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 246.54 E-value: 9.93e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 6 NQDLETKIIHWGHSADPTTGALATPIcqtatFAAKTVEHfEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTS 85
Cdd:PRK08247 2 MSTIETKLAQIGNRSDERTGTVNPPV-----YFSTAYRH-EGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 86 GMGAItSTILALVKSGDH-IVSSDgIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLV 164
Cdd:PRK08247 76 GMAAI-QLVMSLFRSGDElIVSSD-LYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQET 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 165 DIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGG-AVAGSKELIDLVRWPSLCcfTGAS 243
Cdd:PRK08247 154 DIAAIAKIAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGlVVAKGQELCERLAYYQNA--AGAV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 244 LPPMSAWMILRGMKTLDMRMKKHCENGLAVAEfleeeenvelvkypALKSHPQyelCKTQMNGLGGGVVSFKLKDG--IN 321
Cdd:PRK08247 232 LSPFDSWLLIRGMKTLALRMRQHEENAKAIAA--------------FLNEQPG---VTDVLYPGRGGMLSFRLQDEewVN 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 322 gltrdqasrRLMNSLELATIATSLGEEHTLVQ----------------MNG--ENLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK08247 295 ---------PFLKSLKLITFAESLGGVESFITypatqthadipeeiriANGvcNRLLRFSVGIENVEDLIADLKQAFKQV 365
|
.
gi 489530182 384 K 384
Cdd:PRK08247 366 K 366
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
1-383 |
1.78e-78 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 247.70 E-value: 1.78e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 1 MSNNiNQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAE 78
Cdd:PRK05994 1 MTDR-SPGFATLAVHAGAQPDPTTGARATPIYQTTSFVFNDADHAASLfgLQAFGNIYTRITNPTNAVLEERVAALEGGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 79 SAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLN 158
Cdd:PRK05994 80 AALAVASGHAAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIAN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 159 PSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV--AGSKELIDLVRWPSL 236
Cdd:PRK05994 160 PGGTVTDIAAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIvdGGTFDWSKSGKYPML 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 237 C------------------CFT-----------GASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVK 287
Cdd:PRK05994 240 SeprpeyhglvlhetfgnfAFAiaarvlglrdlGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 288 YPALKSHPQYELCKTQMNGLGGGVVSFKLKDGIngltrdQASRRLMNSLELATIATSLGEEHTLV---------QMN--- 355
Cdd:PRK05994 320 YAGLPDDPYHALAQKYSPKGAGAVFTFGLKGGY------EAGVKLVSSLKLFSHLANIGDTRSLVihpastthrQLTdeq 393
|
410 420 430
....*....|....*....|....*....|....
gi 489530182 356 ------GENLIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK05994 394 kvaagaGPDVVRLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
11-382 |
1.05e-77 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 244.43 E-value: 1.05e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 11 TKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEELCMTWG--YVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PRK06434 11 TRAVQSGELRDPRFGNVTTPIFETSTFVYPNSEKEAYMDSTRGmpYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDaVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:PRK06434 91 AITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYID-TDRLNSLDFDPSNYDLIYAESITNPTLKVPDIKN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKslAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVA-GSKELID--LVRWPSLccftGASLP 245
Cdd:PRK06434 170 VSSFCHEND--VIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGtNNKSIFNnlVERRKTL----GSNPD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 246 PMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALkshpqyELCKTQMNGLgGGVVSFKLKdgingltR 325
Cdd:PRK06434 244 PIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGF-GGMLSFELR-------S 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489530182 326 DQASRRLMNSLELATIATSLGEEHTLVQMNGE------------------NLIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK06434 310 MEDVHKFIRNLEIPMVAASLGGVESLITLPVEtshsslspeererlgisdNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
10-381 |
7.18e-74 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 236.11 E-value: 7.18e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 10 ETKIIHWGHSADPTTGALATPICQTATFAAKTVE----HFEELC--------MTWGYVYTRECNPTLTELEAKLAMLENA 77
Cdd:PRK07049 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFRSAEdgrdFFDYVSgrkeppagEGAGLVYSRFNHPNSEIVEDRLAVYEGA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 78 ESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVE-VTFVDAVNPQNVKEAM-----RPNTKIV 151
Cdd:PRK07049 99 ESAALFSSGMSAIATTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRVSLI 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 152 YIESPLNPSLDLVDIKTIAEIA------HENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSK 225
Cdd:PRK07049 179 LIETPANPTNSLVDVAAVRRVAdaiearQGHRPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRK 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 226 ELIDLVRwpSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFleeeenvelvkypaLKSHPQYE------- 298
Cdd:PRK07049 259 ALIRQVR--ALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEF--------------LRDHPKVEklhylpf 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 299 ---------LCKTQMNGlGGGVVSFKLKDGingltrDQASRRLMNSLELATIATSLGEEHTLV----QMN---------- 355
Cdd:PRK07049 323 ldpdsaygaVYKRQCTG-AGSTFSFDIKGG------QAAAFRFLNALQIFKLAVSLGGTESLAshpaSMThsgvpadvre 395
|
410 420 430
....*....|....*....|....*....|
gi 489530182 356 ----GENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:PRK07049 396 rigvLESTIRLSIGIEHPDDLIADLAQALD 425
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
2-383 |
5.44e-71 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 228.99 E-value: 5.44e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 2 SNNINQ-DLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH------FEELcmtwGYVYTRECNPTLTELEAKLAML 74
Cdd:PRK05613 6 NSNADQwGFETRSIHAGQSVDSDTSARNLPIYQTTSYVFDSAEHakqrfaLEDL----GPIYSRLTNPTVEALENRIASL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 75 ENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFV-DAVNPQNVKEAMRPNTKIVYI 153
Cdd:PRK05613 82 EGGVHAVAFASGQAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 154 ESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVA----------- 222
Cdd:PRK05613 162 ETFANPQADVLDIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtver 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 223 -----------------------------GSKELIDLVRwpslccFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAV 273
Cdd:PRK05613 242 dgkpvfpyfvtpdpayhglkyadlgapafGLKARAGLLR------DTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 274 AEFLEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGingltRDQAsRRLMNSLELATIATSLGEEHTLV- 352
Cdd:PRK05613 316 AEFLNNHEKVAKVNFAGLKDSPWYATKEKLGLKYTGSVLSFDIKGG-----KDEA-WAFIDALKLHSNLANIGDVRSLVv 389
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 489530182 353 --------QMNGENL---------IRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK05613 390 hpattthsQSDEAGLaragitqatVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
9-380 |
1.48e-70 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 228.37 E-value: 1.48e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTgALATPICQTATFAAKTVEHfeelcmTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PLN02509 87 VSTLLVNLDNKFDPFD-AMSTPLYQTATFKQPSAIE------NGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMA 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AItSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKT 168
Cdd:PLN02509 160 AL-SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRK 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 169 IAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGG--AVAGSKELIDLVrwpSLCCFTGASLPP 246
Cdd:PLN02509 239 IAEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGvlAVKGEKLAKEVY---FLQNSEGSGLAP 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 247 MSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFklkdgINGLTrd 326
Cdd:PLN02509 316 FDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKG-AGSVFSF-----ITGSV-- 387
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 327 QASRRLMNSLELATIATSLGEEHTLVQMN------------------GENLIRIAVGLESSNDIINDFKQAI 380
Cdd:PLN02509 388 ALSKHLVETTKYFSIAVSFGSVKSLISMPcfmshasipaevrearglTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
11-382 |
5.08e-67 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 217.55 E-value: 5.08e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 11 TKIIHWGHSADPTTGALATPICQTATFAaktvehFEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAI 90
Cdd:PRK08776 15 TAAVRAGIDRDTAYGAVTPPIVLSSNFS------FDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 91 TSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIA 170
Cdd:PRK08776 89 NLVLNALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 171 EIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELID-LVRWPSLCCFTGAslpPMS 248
Cdd:PRK08776 169 EAAHKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVvARDAELHQqLVWWANALGLTGS---PFD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 249 AWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDGingltrDQA 328
Cdd:PRK08776 246 AFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGF-GAMLSFELEGG------EAA 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 329 SRRLMNSLELATIATSLGEEHTLV---------QMNGE---------NLIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK08776 319 VRAFVDGLRYFTLAESLGGVESLIahpasmthaAMTAEaraaagisdGLLRLSVGIESAEDLLIDLRAGLAR 390
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
54-356 |
1.45e-65 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 214.24 E-value: 1.45e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 54 YVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELL-SKFGVEVTFV 132
Cdd:PLN02242 68 YIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLLQLCSSGGHVVASNTLYGGTHALLAHFLpRKCNITTTFV 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 133 DAVNPQNVKEAMRPN-TKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFgTPIVQRPIDLGADLVIHSLTKFIN 211
Cdd:PLN02242 148 DITDLEAVKKAVVPGkTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTF-APMVLSPARLGADVVVHSISKFIS 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 212 GHGDTLGGAVAGSKELIDLVRWPSL--CCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELvkYP 289
Cdd:PLN02242 227 GGADIIAGAVCGPAELVNSMMDLHHgaLMLLGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELGLKVI--YP 304
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489530182 290 ALKSHPQYELCKTQMN-GLG-GGVVSFKLKdginglTRDQASrRLMNSLELAT----IATSLGEEHTLVQMNG 356
Cdd:PLN02242 305 GLEDHPQHALLKSMANkGYGfGGLLCLDMD------TEERAN-RLMRYLQNSTqfgfMAVSLGYYETLMSCSG 370
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
17-381 |
6.51e-63 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 206.28 E-value: 6.51e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 17 GHSADPTTGALATPICQTATFaaktveHFEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILA 96
Cdd:PRK08045 13 GLNDDEQYGCVVPPIHLSSTY------NFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 97 LVKSGDHIVSSDGIFSHT-KLFMSelLSKFGV-EVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAH 174
Cdd:PRK08045 87 FLKPGDLLVAPHDCYGGSyRLFDS--LAKRGCyRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 175 ENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELI-DLVRWPSLCCFTGASLppmSAWMI 252
Cdd:PRK08045 165 EAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVViAKDPDVVtELAWWANNIGVTGGAF---DSYLL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 253 LRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLkDGingltRDQASRRL 332
Cdd:PRK08045 242 LRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGF-GAMLSFEL-DG-----DEQTLRRF 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489530182 333 MNSLELATIATSLGEEHTLVQMNG------------------ENLIRIAVGLESSNDIINDFKQAIE 381
Cdd:PRK08045 315 LGGLSLFTLAESLGGVESLISHAAtmthagmapearaaagisETLLRISTGIEDGEDLIADLENGFR 381
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
17-382 |
1.97e-61 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 202.43 E-value: 1.97e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 17 GHSADPTTGALATPICQTATFAaktvehFEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILA 96
Cdd:PRK08861 14 GIESDSQYHAVVPPIYLSTNYG------FPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLWVSA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 97 LVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHEN 176
Cdd:PRK08861 88 LLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAKAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 177 KSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELIDLVRWPSLCcfTGASLPPMSAWMILRG 255
Cdd:PRK08861 168 GALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLiTKTKEHAEELAWWGNC--IGATGTPFDSYMTLRG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 256 MKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLgGGVVSFKLKDGINGLtrdqasRRLMNS 335
Cdd:PRK08861 246 IRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGF-GSMLSFEFAGSFEQL------KVFVKA 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489530182 336 LELATIATSLGEEHTLV---------QMNGE---------NLIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK08861 319 LALFSLAESLGGVESLIchpasmthrAMGEEalaeagvsqQLLRLSVGLEDAQDLIADLDQAFAK 383
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
9-381 |
4.31e-59 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 195.81 E-value: 4.31e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTGALATPICQTATFaaktvEHfEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMG 88
Cdd:PRK07269 7 INTILAQAGIKSDEATGALVTPLHFSTTY-----QH-PEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 89 AItstILAL--VKSGDHIVSSDGIFSHTKLFMSELlSKFGvEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDI 166
Cdd:PRK07269 81 AI---VLAFsvFPVGSKVVAVRDLYGGSFRWFNQQ-EKEG-RFHFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 167 KTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELIDLVRWPSLCcfTGASLP 245
Cdd:PRK07269 156 EKVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVvTNDLELYEKLFYNLNT--TGAVLS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 246 PMSAWMILRGMKTLDMRMKKHCENGLAVAefleeeenVELVKYPALKshpqyELCKTQMnglgGGVVSFKLKDgingltr 325
Cdd:PRK07269 234 PFDSYLLMRGLKTLSLRMERSTANAQEVV--------AFLKKSPAVK-----EVLYTGK----GGMISFKVAD------- 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489530182 326 DQASRRLMNSLELATIATSLGEEHTLV-----QMNGE-------------NLIRIAVGLESSNDIINDFKQAIE 381
Cdd:PRK07269 290 ETRIPHILNSLKVFTFAESLGGVESLItypttQTHADipaevrhsygltdDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
9-382 |
2.12e-56 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 189.56 E-value: 2.12e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 9 LETKIIHWGHSADPTTGALATPICQTATFAAKTVE--HFEELCMTWG-YVYTRECNPTLTELEAKLAMLENAESAISSTS 85
Cdd:PRK09028 5 KATKIVSAGRDKKWTKGVINPPVFRASTVVFDTVAemRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTALYPS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 86 GMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVD 165
Cdd:PRK09028 85 GAAAISNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 166 IKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDT-LGGAVAGSKelidlvRWPSL---CCFTG 241
Cdd:PRK09028 165 VPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVmLGTATANEK------HWDQLrehSYLMG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 242 ASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDG-I 320
Cdd:PRK09028 239 QCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSG-SNGLFSFVLKQGdP 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489530182 321 NGLTR--DQASRRLM-------NSLELATiaTSLGEEHTLVQMNGEN-LIRIAVGLESSNDIINDFKQAIEK 382
Cdd:PRK09028 318 KAVTAlvEGMQHFKMgfswggfESLILGV--FGINKLRTATNWDFSKpLIRLHIGLEDVDDLIADLEAGFER 387
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
6-375 |
5.16e-53 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 180.77 E-value: 5.16e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 6 NQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEElcMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTS 85
Cdd:PRK05967 10 KAGINTRLAHDGNDPGDYHGFVNPPVVHASTVLFPDAETMAT--RGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 86 GMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVD 165
Cdd:PRK05967 88 GLAAVTVPFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 166 IKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAVAGSKElidlvRWPSLC---CFTGA 242
Cdd:PRK05967 168 IPAIAEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEK-----CWPQLLeahGTLGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 243 SLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDGING 322
Cdd:PRK05967 243 CAGPDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSG-ASGIFSFVLAAGPEK 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489530182 323 LTRDQASrrLMNSLELATIATSLGEEHTL---VQMNGEN---------LIRIAVGLESSNDIIND 375
Cdd:PRK05967 322 GKAKAHA--FLDALEIFGLGYSWGGYESLalhVKLGDRTvakapyagpVIRLQIGLEDVPDLKAD 384
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
8-383 |
9.29e-47 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 164.13 E-value: 9.29e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 8 DLETKIIHWGHSADPTTGALATPICQTATFAAKTVEHFEELcmTWG----YVYTRECNPTLTELEAKLAMLENAESAISS 83
Cdd:PRK07050 9 ALQTRIVQPDDQIPPGFRSFVTPVARASTVVFPDLATMRAL--DWRqdvqWRYGLHATPTSLALAQRLAEIEGGRHALLQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 84 TSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDL 163
Cdd:PRK07050 87 PSGLAAISLVYFGLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 164 VDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV-AGSKELIDLVRWPSLCCftGA 242
Cdd:PRK07050 167 PDVPAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATiTADAELHAKLKLARMRL--GI 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 243 SLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVVSFKLKDGIng 322
Cdd:PRK07050 245 GVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTG-AGGLFSVVFDERY-- 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489530182 323 lTRDQASrRLMNSLELATIATSLGEEHTLV------QMNGEN------LIRIAVGLESSNDIINDFKQAIEKL 383
Cdd:PRK07050 322 -SPAQVD-AFVEALELFAIGWSWGGACSLAmpydvaSMRTAKwphrgtLVRLYIGLEDEADLIADLEQALEAA 392
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
30-380 |
2.85e-46 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 163.69 E-value: 2.85e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 30 PICQTATFAAKTVEHFEEL--CMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSS 107
Cdd:PRK06702 27 PLYQSTTYKYDTSDDLAALfnLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMLAVLNICSSGDHLLCS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 108 DGIFSHTKLFMSELLSKFGVEVTFVDA-VNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTF 186
Cdd:PRK06702 107 STVYGGTFNLFGVSLRKLGIDVTFFNPnLTADEIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELEVPFIVDNTL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 187 GTPIVQRPIDLGADLVIHSLTKFINGHGDTLGGAV--AGSKELIDlVRWPSLC----CFTGAS----------------- 243
Cdd:PRK06702 187 ATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVidGGNFDWTN-GKYPELVepdpSYHGVSyvqnfgaaayivkarvq 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 244 --------LPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFK 315
Cdd:PRK06702 266 llrdygncMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNENYSLAQKYLKKGASGVLTFG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 316 LKDGIngltrdQASRRLMNSLELATIATSLGEEHTLV---------QMNGE---------NLIRIAVGLESSNDIINDFK 377
Cdd:PRK06702 346 IKGGL------EAAKEFIANVKLATLVTHVADARTCVihpastthrQLSAEdqrlagvtsDLIRLSVGIEDVSDIIADLE 419
|
...
gi 489530182 378 QAI 380
Cdd:PRK06702 420 AAL 422
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
7-384 |
4.41e-44 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 157.17 E-value: 4.41e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 7 QDLETKIIHWGHSADPTTGALaTPICQTA------TFAAKtvEHFEELCMTWGYVYTREcnPTLTELEAKLAM--LENAE 78
Cdd:PRK08114 4 KKLDTQLVNAGRSKKYTQGSV-NSVIQRAsslvfdSVEAK--KHATRNRANGELFYGRR--GTLTHFSLQEAMceLEGGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 79 SAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLN 158
Cdd:PRK08114 79 GCALYPCGAAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 159 PSLDLVDIKTIAEIAHENKSLAIV--DSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDT-LGGAVAGSKelidlvRWPS 235
Cdd:PRK08114 159 ITMEVHDVPAIVAAVRSVNPDAVImiDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAmIGTAVANAR------CWEQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 236 L---CCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEFLEEEENVELVKYPALKSHPQYELCKTQMNGlGGGVV 312
Cdd:PRK08114 233 LrenSYLMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTG-SSGLF 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 313 SFKLKDginGLTRDQASrRLMNSLELATIATSLG-----------EEHTLVQMNGE-----NLIRIAVGLESSNDIINDF 376
Cdd:PRK08114 312 SFVLKK---KLTDEQLA-NYLDNFSLFSMAYSWGgfeslilanqpEEIAAIRPAGEvdftgTLIRLHIGLEDVDDLIADL 387
|
....*...
gi 489530182 377 KQAIEKLK 384
Cdd:PRK08114 388 AAGFARIV 395
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
66-269 |
2.96e-12 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 67.20 E-value: 2.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 66 ELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDgiFSHTKLFMSELLSKFGVeVTF----VDAVNPQnVK 141
Cdd:cd06454 50 ELEEELAEFHGKEAALVFSSGYAANDGVLSTLAGKGDLIISDS--LNHASIIDGIRLSGAKK-RIFkhndMEDLEKL-LR 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 142 EAMRPNT-KIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVD---ST-----FGTPIVQRPIDLGA-DLVIHSLTKFIN 211
Cdd:cd06454 126 EARRPYGkKLIVTEGVYSMDGDIAPLPELVDLAKKYGAILFVDeahSVgvygpHGRGVEEFGGLTDDvDIIMGTLGKAFG 205
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489530182 212 GHGdtlgGAVAGSKELIDLVRwpSLC---CFTgASLPPMSAWMILRGMKTL---DMRMKKHCEN 269
Cdd:cd06454 206 AVG----GYIAGSKELIDYLR--SYArgfIFS-TSLPPAVAAAALAALEVLqggPERRERLQEN 262
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
67-231 |
9.14e-12 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 65.90 E-value: 9.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 67 LEAKLAMLENAESAI---SSTSGMGAITSTILALVKSGDHIVS----------------SDGIFShtklfmselLSKFGV 127
Cdd:COG4100 62 LERVYADVFGAEDALvrpQIVSGTHAIALALFGVLRPGDELLSitgkpydtleevigirGEGQGS---------LKEFGI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 128 EVTFVD-----AVNPQNVKEAMRPNTKIVYIE-SP---LNPSLDLVDIKTIAEIAHENKSLAI--VDSTFGTPI-VQRPI 195
Cdd:COG4100 133 SYRQVPltedgKIDLEAIKKAINEKTKMVLIQrSRgysWRPSLTIEEIGEIIKFVKSINPDVIcfVDNCYGEFVeTREPT 212
|
170 180 190
....*....|....*....|....*....|....*....
gi 489530182 196 DLGADLVIHSLTKFINGhgdTL---GGAVAGSKELIDLV 231
Cdd:COG4100 213 EVGADLMAGSLIKNPGG---GLaptGGYIAGRKDLVELA 248
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
64-223 |
5.25e-10 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 57.78 E-value: 5.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 64 LTELEAKLAML--ENAESAISSTSGMGAITSTILALVKSGDHIVSSD-GIFSHTKLFmselLSKFGVEVTFVDAVNPQN- 139
Cdd:cd01494 2 LEELEEKLARLlqPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDAnGHGSRYWVA----AELAGAKPVPVPVDDAGYg 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 140 -------VKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTP----IVQRPIDLGADLVIHSLTK 208
Cdd:cd01494 78 gldvailEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGaspaPGVLIPEGGADVVTFSLHK 157
|
170
....*....|....*
gi 489530182 209 finghgdTLGGAVAG 223
Cdd:cd01494 158 -------NLGGEGGG 165
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
62-232 |
5.66e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 60.54 E-value: 5.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 62 PTLTELEAKLAMLENAESAISStSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSellsKFGVEVTFVDAVNPQN-- 139
Cdd:PRK06225 69 PELRELILKDLGLDDDEALITA-GATESLYLVMRAFLSPGDNAVTPDPGYLIIDNFAS----RFGAEVIEVPIYSEECny 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 140 ------VKEAMRPNTKIVYIESPLNP---SLDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGAD----LVIHSL 206
Cdd:PRK06225 144 kltpelVKENMDENTRLIYLIDPLNPlgsSYTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYApehtVTSYSF 223
|
170 180
....*....|....*....|....*.
gi 489530182 207 TKFINGHGDTLgGAVAGSKELIDLVR 232
Cdd:PRK06225 224 SKIFGMAGLRI-GAVVATPDLIEVVK 248
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
76-268 |
2.08e-09 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 58.51 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 76 NAESAISSTSGMGAITSTILALVKSGDHIVssdgIFSHTKLFMSELLSKFGVEVTFV-------DAVNPQNVKEAMRPNT 148
Cdd:cd00609 58 PPEEIVVTNGAQEALSLLLRALLNPGDEVL----VPDPTYPGYEAAARLAGAEVVPVpldeeggFLLDLELLEAAKTPKT 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 149 KIVYIESPLNPS---LDLVDIKTIAEIAHENKSLAIVDSTF------GTPIVQRPIDLGAD--LVIHSLTKFINGHGDTL 217
Cdd:cd00609 134 KLLYLNNPNNPTgavLSEEELEELAELAKKHGILIISDEAYaelvydGEPPPALALLDAYErvIVLRSFSKTFGLPGLRI 213
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 489530182 218 GGAVAGSKELIDLVRwpSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCE 268
Cdd:cd00609 214 GYLIAPPEELLERLK--KLLPYTTSGPSTLSQAAAAAALDDGEEHLEELRE 262
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
64-252 |
8.96e-09 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 56.54 E-value: 8.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 64 LTELEAKLAML--------ENAESAISSTSGMGAITSTILALVK-SGDHIVSSDGIFSHtklfMSELLSKFGVEVTFVDA 134
Cdd:pfam00155 41 HPELREALAKFlgrspvlkLDREAAVVFGSGAGANIEALIFLLAnPGDAILVPAPTYAS----YIRIARLAGGEVVRYPL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 135 VNPQN-------VKEAMRPNTKIVYIESPLNPS---LDLVDIKTIAEIAHENKSLAIVDST-----FGTPIVQRPIDLGA 199
Cdd:pfam00155 117 YDSNDfhldfdaLEAALKEKPKVVLHTSPHNPTgtvATLEELEKLLDLAKEHNILLLVDEAyagfvFGSPDAVATRALLA 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 489530182 200 D----LVIHSLTKFINGHGDTLgGAVAGSKELID-LVRWPSLCCFTGASLPPMSAWMI 252
Cdd:pfam00155 197 EgpnlLVVGSFSKAFGLAGWRV-GYILGNAAVISqLRKLARPFYSSTHLQAAAAAALS 253
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
64-247 |
5.29e-08 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 54.18 E-value: 5.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 64 LTELEAKLAMLENAESA--I----SSTSGMGAITSTILALVKSGDHIVSSDgIFSHTKLFMSELLSKF-GVEVTF--VDA 134
Cdd:pfam00266 45 YEEAREKVAEFINAPSNdeIiftsGTTEAINLVALSLGRSLKPGDEIVITE-MEHHANLVPWQELAKRtGARVRVlpLDE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 135 ---VNPQNVKEAMRPNTKIVYIeSPLNPSLDLV-DIKTIAEIAHENKSLAIVDSTFGtpIVQRPID---LGADLVIHSLT 207
Cdd:pfam00266 124 dglLDLDELEKLITPKTKLVAI-THVSNVTGTIqPVPEIGKLAHQYGALVLVDAAQA--IGHRPIDvqkLGVDFLAFSGH 200
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 489530182 208 KFingHGDTLGGAVAGSKELI----------DLVRWPSLCCFTGASLPPM 247
Cdd:pfam00266 201 KL---YGPTGIGVLYGRRDLLekmppllgggGMIETVSLQESTFADAPWK 247
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
63-187 |
3.76e-06 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 48.44 E-value: 3.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 63 TLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHI-VSSDGIFSHTklfMSELLSKFGVEVTFVD-----AVN 136
Cdd:cd06451 36 EILEGLRYVFQTENGLTFLLSGSGTGAMEAALSNLLEPGDKVlVGVNGVFGDR---WADMAERYGADVDVVEkpwgeAVS 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 137 PQNVKEAMRPNT----KIVYIESP---LNPsldlvdIKTIAEIAHENKSLAIVD--STFG 187
Cdd:cd06451 113 PEEIAEALEQHDikavTLTHNETStgvLNP------LEGIGALAKKHDALLIVDavSSLG 166
|
|
| PLN03227 |
PLN03227 |
serine palmitoyltransferase-like protein; Provisional |
66-249 |
7.72e-06 |
|
serine palmitoyltransferase-like protein; Provisional
Pssm-ID: 178766 [Multi-domain] Cd Length: 392 Bit Score: 47.59 E-value: 7.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 66 ELEAKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIF-----------SHTKLF----MSELLSKFG-VEV 129
Cdd:PLN03227 47 ELEQCMAEFLGTESAILYSDGASTTSSTVAAFAKRGDLLVVDRGVNeallvgvslsrANVRWFrhndMKDLRRVLEqVRA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 130 TFVDAVNPQNVKEamrpntKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFG-----------TPIVQRPIDLG 198
Cdd:PLN03227 127 QDVALKRKPTDQR------RFLVVEGLYKNTGTLAPLKELVALKEEFHYRLILDESFSfgtlgksgrgsLEHAGLKPMVH 200
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 489530182 199 ADLVIHSLTKFINghgdTLGGAVAGSKELIDLVRWP-SLCCFTgASLPPMSA 249
Cdd:PLN03227 201 AEIVTFSLENAFG----SVGGMTVGSEEVVDHQRLSgSGYCFS-ASAPPFLA 247
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
76-232 |
2.17e-05 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 46.28 E-value: 2.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 76 NAESAISSTSGMGAITSTILALVKSGDHIVSSD-GIFSHTklFMSELlskFGVEVTFVD-------AVNPQNVKEAMRPN 147
Cdd:COG0436 89 DPDEILVTNGAKEALALALLALLNPGDEVLVPDpGYPSYR--AAVRL---AGGKPVPVPldeengfLPDPEALEAAITPR 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 148 TKIVYIESPLNPS---LDLVDIKTIAEIAHENKSLAIVDS-----TFG----TPIVQRPidlGAD---LVIHSLTKfing 212
Cdd:COG0436 164 TKAIVLNSPNNPTgavYSREELEALAELAREHDLLVISDEiyeelVYDgaehVSILSLP---GLKdrtIVINSFSK---- 236
|
170 180
....*....|....*....|....*.
gi 489530182 213 hgdTLG------GAVAGSKELIDLVR 232
Cdd:COG0436 237 ---SYAmtgwriGYAVGPPELIAALL 259
|
|
| GDC-P |
cd00613 |
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine ... |
122-229 |
2.25e-05 |
|
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T. The reaction catalysed by this protein is: Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2. Alpha-beta-type dimers associate to form an alpha(2)beta(2) tetramer, where the alpha- and beta-subunits are structurally similar and appear to have arisen by gene duplication and subsequent divergence with a loss of one active site. The members of this CD are widely dispersed among all three forms of cellular life.
Pssm-ID: 99737 [Multi-domain] Cd Length: 398 Bit Score: 46.07 E-value: 2.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 122 LSKFGVEVTFVDA-----VNPQNVKEAMRPNTKIVYIEsplNPSLDLV---DIKTIAEIAHENKSLAIVDstfGTP---- 189
Cdd:cd00613 129 GEPLGIEVVEVPSdeggtVDLEALKEEVSEEVAALMVQ---YPNTLGVfedLIKEIADIAHSAGALVYVD---GDNlnlt 202
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 489530182 190 IVQRPIDLGADLVIHSLTKFINGHGdtLGGAVAG----SKELID 229
Cdd:cd00613 203 GLKPPGEYGADIVVGNLQKTGVPHG--GGGPGAGffavKKELVR 244
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
95-229 |
5.44e-05 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 44.74 E-value: 5.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 95 LALVKSGDHIVSSD-----GIFShtklfMSELLSKFGVEVTFVD-----AVNPQNVKEAMRPNTKIVYIESPLNpSLDLV 164
Cdd:COG0520 97 LGRLKPGDEILITEmehhsNIVP-----WQELAERTGAEVRVIPldedgELDLEALEALLTPRTKLVAVTHVSN-VTGTV 170
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489530182 165 -DIKTIAEIAHENKSLAIVD---StfgtpIVQRPID---LGADLVihsltkFINGH---GDTLGGAVAGSKELID 229
Cdd:COG0520 171 nPVKEIAALAHAHGALVLVDgaqS-----VPHLPVDvqaLGCDFY------AFSGHklyGPTGIGVLYGKRELLE 234
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
164-232 |
1.20e-04 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 43.96 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 164 VDIKTIAEIAHENKSLAIVD---------STFGT---PIVQRPIDLGADLVIHSltkfinghGDTL-----GGAVAGSKE 226
Cdd:COG1921 175 VSLAELAELAHEHGLPVIVDlgsgslvdlSKYGLphePTVQEYLAAGADLVTFS--------GDKLlggpqAGIIVGKKE 246
|
....*.
gi 489530182 227 LIDLVR 232
Cdd:COG1921 247 LIERIK 252
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
70-229 |
1.28e-04 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 43.61 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 70 KLAMLENAESA--I----SSTSGMGAITSTILALVKSGDHIVSSdgifshtklfMSE----------LLSKFGVEVTFVD 133
Cdd:cd06453 51 KVARFINAPSPdeIiftrNTTEAINLVAYGLGRANKPGDEIVTS----------VMEhhsnivpwqqLAERTGAKLKVVP 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 134 A-----VNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKSLAIVDSTFGTPivQRPID---LGADLVIHS 205
Cdd:cd06453 121 VdddgqLDLEALEKLLTERTKLVAVTHVSNVLGTINPVKEIGEIAHEAGVPVLVDGAQSAG--HMPVDvqdLGCDFLAFS 198
|
170 180
....*....|....*....|....*..
gi 489530182 206 ltkfinGH---GDTLGGAVAGSKELID 229
Cdd:cd06453 199 ------GHkmlGPTGIGVLYGKEELLE 219
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
76-186 |
5.52e-04 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 41.77 E-value: 5.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 76 NAESAISSTSG-MGAITSTILALVKSGDHIVssdgIFSHTKLFMSELLSKFGVEVTFVD------AVNPQNVKEAMRPNT 148
Cdd:PLN00175 113 DPEKEVTVTSGcTEAIAATILGLINPGDEVI----LFAPFYDSYEATLSMAGAKIKTVTlrppdfAVPEDELKAAFTSKT 188
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 489530182 149 KIVYIESPLNPSLDLV---DIKTIAEIAHENKSLAIVDSTF 186
Cdd:PLN00175 189 RAILINTPHNPTGKMFtreELELIASLCKENDVLAFTDEVY 229
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
127-203 |
8.10e-04 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 41.28 E-value: 8.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 127 VEVTFVDAV-NPQNVKEAMRPNTKIVYIESPlN--PSLDlvDIKTIAEIAHENKSLAIVdstfGT-PI----VQRPIDLG 198
Cdd:PRK00451 183 VEVPYEDGVtDLEALEAAVDDDTAAVVVQYP-NffGVIE--DLEEIAEIAHAGGALFIV----GVdPVslglLKPPGEYG 255
|
....*
gi 489530182 199 ADLVI 203
Cdd:PRK00451 256 ADIVV 260
|
|
| GcvP1 |
COG0403 |
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport ... |
125-203 |
1.55e-03 |
|
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440172 [Multi-domain] Cd Length: 442 Bit Score: 40.40 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489530182 125 FGVEVTFVD----AVNPQNVKEAMRPNTKIVYIESPlNPSLDLVDIKTIAEIAHENKSLAIVdstfGT-PI----VQRPI 195
Cdd:COG0403 179 LGIEVVEVPdedgVTDLEALKALLDDDVAGVLVQYP-NFFGVIEDLRAIAEAAHAAGALVIV----AAdPLslglLKPPG 253
|
....*...
gi 489530182 196 DLGADLVI 203
Cdd:COG0403 254 ELGADIVV 261
|
|
| |
