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Conserved domains on  [gi|489533114|ref|WP_003437844|]
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low molecular weight protein arginine phosphatase [Clostridioides difficile]

Protein Classification

low molecular weight protein arginine phosphatase( domain architecture ID 11611418)

low molecular weight protein arginine phosphatase is a member of the low molecular weight phosphatase (LMWP) family, sharing a highly conserved active site motif (V/I)CXGNTCRS; it has been shown that the conserved threonine, which is an isoleucine in many LMWPTPs, confers specificity to phosphoarginine over phosphotyrosine; similar to Bacillus subtilis YwlE which catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LMWPAP cd16344
low molecular weight protein arginine phosphatase; Low molecular weight protein arginine ...
 1-147 2.21e-77

low molecular weight protein arginine phosphatase; Low molecular weight protein arginine phosphatases are part of the low molecular weight phosphatase (LMWP) family. They share a highly conserved active site motif (V/I)CXGNTCRS. It has been shown that the conserved threonine, which in many LMWPTPs is an isoleucine, confers specificity to phosphoarginine over phosphotyrosine.


:

Pssm-ID: 319972  Cd Length: 142  Bit Score: 225.78  E-value: 2.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKEsgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDE 80
Cdd:cd16344    1 MKILFVCTGNTCRSPMAEAILKKLLEE-----LDVEVKSAGIFAVDGSPASPNAVEVLKEKGIDLSGHRSQQLTEELLEW 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489533114  81 SDIILTMTKSHKEILVQAVPKCKEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:cd16344   76 ADLILTMTESHKQALLSLYPEAADKVFTLKEYVGGEDGDISDPFGGSLEVYRQTAEELEELIEKLLK 142
 
Name Accession Description Interval E-value
LMWPAP cd16344
low molecular weight protein arginine phosphatase; Low molecular weight protein arginine ...
 1-147 2.21e-77

low molecular weight protein arginine phosphatase; Low molecular weight protein arginine phosphatases are part of the low molecular weight phosphatase (LMWP) family. They share a highly conserved active site motif (V/I)CXGNTCRS. It has been shown that the conserved threonine, which in many LMWPTPs is an isoleucine, confers specificity to phosphoarginine over phosphotyrosine.


Pssm-ID: 319972  Cd Length: 142  Bit Score: 225.78  E-value: 2.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKEsgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDE 80
Cdd:cd16344    1 MKILFVCTGNTCRSPMAEAILKKLLEE-----LDVEVKSAGIFAVDGSPASPNAVEVLKEKGIDLSGHRSQQLTEELLEW 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489533114  81 SDIILTMTKSHKEILVQAVPKCKEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:cd16344   76 ADLILTMTESHKQALLSLYPEAADKVFTLKEYVGGEDGDISDPFGGSLEVYRQTAEELEELIEKLLK 142
Wzb COG0394
Protein-tyrosine-phosphatase [Signal transduction mechanisms];
1-149 1.41e-44

Protein-tyrosine-phosphatase [Signal transduction mechanisms];


Pssm-ID: 440163  Cd Length: 137  Bit Score: 142.61  E-value: 1.41e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKEsgrsieEYSISSAGisTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDE 80
Cdd:COG0394    4 KRVLFVCTGNICRSPMAEALLRHLAGG------RVEVDSAG--TEPGGPVDPRAVAVLAERGIDLSGHRSRQLDEEDLPE 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489533114  81 SDIILTMTKSHKEILVQAVPKCKEKVYTFkgfankneeDISDPFGGNLDIYRSTMREIMYSVNEIVKKI 149
Cdd:COG0394   76 FDLVITMCDSAAEELCPLFPGAAKLLLHW---------DVPDPYYGGLEAFREVRDEIERRIEALLAKL 135
LMWPc pfam01451
Low molecular weight phosphotyrosine protein phosphatase;
3-142 2.19e-34

Low molecular weight phosphotyrosine protein phosphatase;


Pssm-ID: 460216  Cd Length: 142  Bit Score: 117.09  E-value: 2.19e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114    3 ILIVCTGNTCRSPMAEAILRKAIKESGRSIEeYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESD 82
Cdd:pfam01451   1 ILFVCTGNICRSPMAEAIFRRELEKAGLGDK-VEVDSAGTGAWPGNPADPRAVEVLKEHGIDLSGHYARQLSTEDFASFD 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489533114   83 IILTMTKSHK-EILVQAVPKCKEKVYTFKGFAnkNEEDISDPFGGNLDIYRSTMREIMYSV 142
Cdd:pfam01451  80 LILAMDSEHKrDLCPLAPERYRAKVMLLGEYG--EQLDIPDPYYGSIDAFEEVRDLIERRC 138
LMWPc smart00226
Low molecular weight phosphatase family;
3-147 1.69e-33

Low molecular weight phosphatase family;


Pssm-ID: 197586  Cd Length: 134  Bit Score: 114.49  E-value: 1.69e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114     3 ILIVCTGNTCRSPMAEAILRKAIKesgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKvITKKLIDESD 82
Cdd:smart00226   1 ILFVCTGNICRSPMAEALFKAYVG------DRVKIDSAGTGAWVGGGADPRAVKVLKEHGIDLSHHASQ-LTSSDFKNAD 73

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489533114    83 IILTMTKSHKEILVQAVPKCKEKVYTFKGFAnkneeDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:smart00226  74 LVLAMDGSHLRNICRLKPPSRAKVELFGHYV-----DVDDPYYGGIDGFERVYDELENALQEFLK 133
PRK10126 PRK10126
low molecular weight protein-tyrosine-phosphatase Wzb;
2-124 1.12e-21

low molecular weight protein-tyrosine-phosphatase Wzb;


Pssm-ID: 182256  Cd Length: 147  Bit Score: 84.58  E-value: 1.12e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   2 NILIVCTGNTCRSPMAEAILRkaikesgRSIEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDES 81
Cdd:PRK10126   4 NILVVCVGNICRSPTAERLLQ-------RYHPELKVESAGLGALVGKGADPTAISVAAEHQLSLEGHCARQISRRLCRNY 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 489533114  82 DIILTMTKSHKEILVQAVPKCKEKVYTFKGFanKNEEDISDPF 124
Cdd:PRK10126  77 DLILTMEKRHIERLCEMAPEMRGKVMLFGHW--DNECEIPDPY 117
arsC_pI258_fam TIGR02691
arsenate reductase (thioredoxin); This family describes the well-studied thioredoxin-dependent ...
 3-87 2.51e-17

arsenate reductase (thioredoxin); This family describes the well-studied thioredoxin-dependent arsenate reductase of Staphylococcus aureaus plasmid pI258 and other mechanistically similar arsenate reductases. The mechanism involves an intramolecular disulfide bond cascade, and aligned members of this family have four absolutely conserved Cys residues. This group of arsenate reductases belongs to the low-molecular weight protein-tyrosine phosphatase family (pfam01451), as does a group of glutathione/glutaredoxin type arsenate reductases (TIGR02689). At least two other, non-homologous groups of arsenate reductases involved in arsenical resistance are also known. This enzyme reduces arsenate to arsenite, which may be more toxic but which is more easily exported. [Cellular processes, Detoxification]


Pssm-ID: 131738  Cd Length: 129  Bit Score: 72.89  E-value: 2.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114    3 ILIVCTGNTCRSPMAEAILRKAIKesgrsiEEYSISSAGISTangMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESD 82
Cdd:TIGR02691   1 IYFLCTGNSCRSQMAEGWGKKYLG------DEWEVYSAGIEA---HGLNPNAVKAMKEVGIDISNQTSDLIDLDILNKAD 71


                  ....*
gi 489533114   83 IILTM 87
Cdd:TIGR02691  72 LVVTL 76
 
Name Accession Description Interval E-value
LMWPAP cd16344
low molecular weight protein arginine phosphatase; Low molecular weight protein arginine ...
 1-147 2.21e-77

low molecular weight protein arginine phosphatase; Low molecular weight protein arginine phosphatases are part of the low molecular weight phosphatase (LMWP) family. They share a highly conserved active site motif (V/I)CXGNTCRS. It has been shown that the conserved threonine, which in many LMWPTPs is an isoleucine, confers specificity to phosphoarginine over phosphotyrosine.


Pssm-ID: 319972  Cd Length: 142  Bit Score: 225.78  E-value: 2.21e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKEsgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDE 80
Cdd:cd16344    1 MKILFVCTGNTCRSPMAEAILKKLLEE-----LDVEVKSAGIFAVDGSPASPNAVEVLKEKGIDLSGHRSQQLTEELLEW 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489533114  81 SDIILTMTKSHKEILVQAVPKCKEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:cd16344   76 ADLILTMTESHKQALLSLYPEAADKVFTLKEYVGGEDGDISDPFGGSLEVYRQTAEELEELIEKLLK 142
Wzb COG0394
Protein-tyrosine-phosphatase [Signal transduction mechanisms];
1-149 1.41e-44

Protein-tyrosine-phosphatase [Signal transduction mechanisms];


Pssm-ID: 440163  Cd Length: 137  Bit Score: 142.61  E-value: 1.41e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKEsgrsieEYSISSAGisTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDE 80
Cdd:COG0394    4 KRVLFVCTGNICRSPMAEALLRHLAGG------RVEVDSAG--TEPGGPVDPRAVAVLAERGIDLSGHRSRQLDEEDLPE 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489533114  81 SDIILTMTKSHKEILVQAVPKCKEKVYTFkgfankneeDISDPFGGNLDIYRSTMREIMYSVNEIVKKI 149
Cdd:COG0394   76 FDLVITMCDSAAEELCPLFPGAAKLLLHW---------DVPDPYYGGLEAFREVRDEIERRIEALLAKL 135
LMWPTP cd16343
Low molecular weight protein tyrosine phosphatase; Low molecular weight protein tyrosine ...
 1-147 9.15e-43

Low molecular weight protein tyrosine phosphatase; Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.


Pssm-ID: 319971  Cd Length: 147  Bit Score: 138.34  E-value: 9.15e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   1 MNILIVCTGNTCRSPMAEAILRKAIKESGRsiEEYSISSAGISTAN-GMGASENSIEVLKEIGIDLSNHRSKVITKKLID 79
Cdd:cd16343    1 KKILFVCLGNICRSPMAEAVLRHLLPKAGG--DDVEVDSAGTSAWHgGEPPDPRARAVLKEHGIDLSGHRARQLTAEDFD 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489533114  80 ESDIILTMTKSHKEILVQAVPK-CKEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:cd16343   79 EFDLILAMDESNLRDLRRLAPAeARGKVFLLGDFDPEGGKDVPDPYYGGREGFEEVYDLIERACEGLLE 147
LMWP cd00115
Low molecular weight phosphatase family; Low molecular weight phosphatases (LMWPs) are a group ...
 3-147 1.05e-35

Low molecular weight phosphatase family; Low molecular weight phosphatases (LMWPs) are a group of small soluble enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). This family includes protein tyrosine phosphatases, arginine phosphatases and arsenate reductases.


Pssm-ID: 319970  Cd Length: 137  Bit Score: 120.29  E-value: 1.05e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   3 ILIVCTGNTCRSPMAEAILRKAIKesgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLsNHRSKVITKKLIDESD 82
Cdd:cd00115    2 ILFICTGNICRSPMAEAIFKQLLG------DEWKVDSAGTGAHHGEGADPRAVRVLKEVGIDI-SHRSDQIKSEHLDNYD 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489533114  83 IILTMTKSHKEILVQAVPKCKEKVYTFkgFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:cd00115   75 LVLVMDGSNLDKIPRIFPEARGKTWLP--HVKLEHGEIDDPYRGDIEDFRRVRDELENASKRFAE 137
LMWPc pfam01451
Low molecular weight phosphotyrosine protein phosphatase;
3-142 2.19e-34

Low molecular weight phosphotyrosine protein phosphatase;


Pssm-ID: 460216  Cd Length: 142  Bit Score: 117.09  E-value: 2.19e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114    3 ILIVCTGNTCRSPMAEAILRKAIKESGRSIEeYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESD 82
Cdd:pfam01451   1 ILFVCTGNICRSPMAEAIFRRELEKAGLGDK-VEVDSAGTGAWPGNPADPRAVEVLKEHGIDLSGHYARQLSTEDFASFD 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489533114   83 IILTMTKSHK-EILVQAVPKCKEKVYTFKGFAnkNEEDISDPFGGNLDIYRSTMREIMYSV 142
Cdd:pfam01451  80 LILAMDSEHKrDLCPLAPERYRAKVMLLGEYG--EQLDIPDPYYGSIDAFEEVRDLIERRC 138
LMWPc smart00226
Low molecular weight phosphatase family;
3-147 1.69e-33

Low molecular weight phosphatase family;


Pssm-ID: 197586  Cd Length: 134  Bit Score: 114.49  E-value: 1.69e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114     3 ILIVCTGNTCRSPMAEAILRKAIKesgrsiEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKvITKKLIDESD 82
Cdd:smart00226   1 ILFVCTGNICRSPMAEALFKAYVG------DRVKIDSAGTGAWVGGGADPRAVKVLKEHGIDLSHHASQ-LTSSDFKNAD 73

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489533114    83 IILTMTKSHKEILVQAVPKCKEKVYTFKGFAnkneeDISDPFGGNLDIYRSTMREIMYSVNEIVK 147
Cdd:smart00226  74 LVLAMDGSHLRNICRLKPPSRAKVELFGHYV-----DVDDPYYGGIDGFERVYDELENALQEFLK 133
LMWP_ArsC cd16345
Arsenate reductase of the LMWP family; Arsenate reductase plays an important role in the ...
 2-87 7.25e-22

Arsenate reductase of the LMWP family; Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).


Pssm-ID: 319973  Cd Length: 132  Bit Score: 84.81  E-value: 7.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   2 NILIVCTGNTCRSPMAEAILRKAikeSGRSIEEYsisSAGISTAngmGASENSIEVLKEIGIDLSNHRSKVITKKLIDES 81
Cdd:cd16345    1 KVLFLCTGNSARSQMAEALLRHL---GGDRFEAY---SAGSEPA---GVNPLAIEVMKEIGIDISGQRSKSLDEFLGQEF 71


                 ....*.
gi 489533114  82 DIILTM 87
Cdd:cd16345   72 DYVITV 77
PRK10126 PRK10126
low molecular weight protein-tyrosine-phosphatase Wzb;
2-124 1.12e-21

low molecular weight protein-tyrosine-phosphatase Wzb;


Pssm-ID: 182256  Cd Length: 147  Bit Score: 84.58  E-value: 1.12e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   2 NILIVCTGNTCRSPMAEAILRkaikesgRSIEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDES 81
Cdd:PRK10126   4 NILVVCVGNICRSPTAERLLQ-------RYHPELKVESAGLGALVGKGADPTAISVAAEHQLSLEGHCARQISRRLCRNY 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 489533114  82 DIILTMTKSHKEILVQAVPKCKEKVYTFKGFanKNEEDISDPF 124
Cdd:PRK10126  77 DLILTMEKRHIERLCEMAPEMRGKVMLFGHW--DNECEIPDPY 117
PRK13530 PRK13530
arsenate reductase (thioredoxin);
3-107 9.08e-18

arsenate reductase (thioredoxin);


Pssm-ID: 237415  Cd Length: 133  Bit Score: 74.01  E-value: 9.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   3 ILIVCTGNTCRSPMAEAILRKAIKEsgrsieEYSISSAGISTangMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESD 82
Cdd:PRK13530   6 IYFLCTGNSCRSQMAEGWGKQYLGD------KWNVYSAGIEA---HGVNPNAIKAMKEVGIDISNQTSDIIDNDILNNAD 76

                         90       100
                 ....*....|....*....|....*
gi 489533114  83 IILTMTkSHKEILVQAVPKCKEKVY 107
Cdd:PRK13530  77 LVVTLC-SHADDVCPSTPPHVKRVH 100
arsC_pI258_fam TIGR02691
arsenate reductase (thioredoxin); This family describes the well-studied thioredoxin-dependent ...
 3-87 2.51e-17

arsenate reductase (thioredoxin); This family describes the well-studied thioredoxin-dependent arsenate reductase of Staphylococcus aureaus plasmid pI258 and other mechanistically similar arsenate reductases. The mechanism involves an intramolecular disulfide bond cascade, and aligned members of this family have four absolutely conserved Cys residues. This group of arsenate reductases belongs to the low-molecular weight protein-tyrosine phosphatase family (pfam01451), as does a group of glutathione/glutaredoxin type arsenate reductases (TIGR02689). At least two other, non-homologous groups of arsenate reductases involved in arsenical resistance are also known. This enzyme reduces arsenate to arsenite, which may be more toxic but which is more easily exported. [Cellular processes, Detoxification]


Pssm-ID: 131738  Cd Length: 129  Bit Score: 72.89  E-value: 2.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114    3 ILIVCTGNTCRSPMAEAILRKAIKesgrsiEEYSISSAGISTangMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESD 82
Cdd:TIGR02691   1 IYFLCTGNSCRSQMAEGWGKKYLG------DEWEVYSAGIEA---HGLNPNAVKAMKEVGIDISNQTSDLIDLDILNKAD 71


                  ....*
gi 489533114   83 IILTM 87
Cdd:TIGR02691  72 LVVTL 76
etp PRK11391
phosphotyrosine-protein phosphatase; Provisional
 2-131 5.05e-16

phosphotyrosine-protein phosphatase; Provisional


Pssm-ID: 138553  Cd Length: 144  Bit Score: 70.05  E-value: 5.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489533114   2 NILIVCTGNTCRSPMAEAILRKaikesgrSIEEYSISSAGISTANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDES 81
Cdd:PRK11391   4 SILVVCTGNICRSPIGERLLRK-------RLPGVKVKSAGVHGLVKHPADATAADVAANHGVSLEGHAGRKLTAEMARNY 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 489533114  82 DIILTMTKSHKEILVQAVPKCKEKVYTFKGFANKNEedISDPFGGNLDIY 131
Cdd:PRK11391  77 DLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKE--IPDPYRKSQDAF 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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