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MULTISPECIES: xanthine dehydrogenase molybdenum-binding subunit XdhA [Clostridium]
Protein Classification
xanthine dehydrogenase molybdenum-binding subunit XdhA ( domain architecture ID 11484539 )
xanthine dehydrogenase molybdenum-binding subunit XdhA participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism)
List of domain hits
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
6-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1389.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 6 DL IGKS VN RVDA V AKVTG K AKY CS DY FEPDS L VGMVL RSP Y AH A KVK N IDT K EA EN L E GVEAV L T YKN VP NTK FPTAGHP 85
Cdd:PRK09970 1 MA IGKS IM RVDA I AKVTG R AKY TD DY VMAGM L YAKYV RSP I AH G KVK S IDT E EA RS L P GVEAV F T WED VP DIP FPTAGHP 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 86 Y SLDP S HRDI E D YS LLT DKA R FV GDAVAAVVA N DEL I A K KALKLIKVEYE I LP FVM D Q E E A IK EGAP V IH DE R p N N IVSD 165
Cdd:PRK09970 81 W SLDP N HRDI A D RA LLT RHV R HH GDAVAAVVA R DEL T A E KALKLIKVEYE E LP VIT D P E A A LA EGAP P IH NG R - G N LLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 166 FGITV G DPDEVF K N AD KIYK G Q YET Q IVQHC Q ME THNAM A KIDEK GR ML I IT STQIPHIVRR I V SK A CNL P I G RI RVIKP 245
Cdd:PRK09970 160 STMST G NVQQTI K A AD YQVQ G H YET P IVQHC H ME NVTSY A YMEDD GR IT I VS STQIPHIVRR V V GQ A LGI P W G KV RVIKP 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 246 YVGGGFG G KQDV II EPL T A IMSLA V N GR C V RLQ LSREE AIVS TRTRHA MRVN IKM ALSKNNKIE GY DIENFV N N GAYASH 325
Cdd:PRK09970 240 YVGGGFG N KQDV LE EPL A A FLTSK V G GR P V KVS LSREE CFLA TRTRHA FTID IKM GVNRDGTLK GY SLDVLS N T GAYASH 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 326 GHSIA MSA G S K IRP LY DIK A E KY RP KT I YTNLP V AGAMR A YG I PQ MC F VI ESM V DD ICED L N IDPV D FR INSFIKK G HID 405
Cdd:PRK09970 320 GHSIA SAG G N K VAY LY PRC A Y KY SS KT V YTNLP S AGAMR G YG A PQ VV F AV ESM L DD AATA L G IDPV E FR LRNAARE G DAN 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 406 NA SG LVVRTF GLPECL KR GR ELID WD RK R QLY KNQ N G SI R K GVG M ACFSY F SGTWPV S LE A AGAR IV MNQDG S VQVQ V GA 485
Cdd:PRK09970 400 PL SG KRIYSA GLPECL EK GR KIFE WD KR R AEC KNQ Q G NL R R GVG V ACFSY T SGTWPV G LE I AGAR LL MNQDG T VQVQ S GA 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 486 TEIGQGSDTVFSQM A AET I GIP FDM V TIV S Q QDTD I TPFD T G S YASRQS FI AG Q AI K KAA I E V K R K V L EI A SDKCGLD A E 565
Cdd:PRK09970 480 TEIGQGSDTVFSQM V AET V GIP VSD V RVI S T QDTD V TPFD P G A YASRQS YV AG P AI R KAA L E L K E K I L AH A AVMLHQS A M 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 566 L LDI V D AK I IE K GLRREIYT LEE I A LE AYY NR E KYAP IT SDLTV K VKN N AI A Y G A TFV E VEVDI KTG K IKVLD I Y NVHDS 645
Cdd:PRK09970 560 N LDI I D GH I VV K RPGEPLMS LEE L A MD AYY HP E RGGQ IT AESSI K TTT N PP A F G C TFV D VEVDI ALC K VTINR I L NVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 646 G K ILN KK LAEGQVHGG VS M AL G F AL S E KF IIDEKTG SII N N NLL H YKL Q T I MD T P NIKCE FV NT Y D P T S S YG Q KSLGE NT 725
Cdd:PRK09970 640 G H ILN PL LAEGQVHGG MG M GI G W AL F E EM IIDEKTG VVR N P NLL D YKL P T M MD L P QLESA FV EI Y E P Q S A YG H KSLGE PP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 489586032 726 T ISPAPAIRNAVL N ATGVA F N K LPM DA Q TV FE K F RKV GLI 765
Cdd:PRK09970 720 I ISPAPAIRNAVL M ATGVA I N T LPM TP Q RL FE E F KEA GLI 759
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
6-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1389.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 6 DL IGKS VN RVDA V AKVTG K AKY CS DY FEPDS L VGMVL RSP Y AH A KVK N IDT K EA EN L E GVEAV L T YKN VP NTK FPTAGHP 85
Cdd:PRK09970 1 MA IGKS IM RVDA I AKVTG R AKY TD DY VMAGM L YAKYV RSP I AH G KVK S IDT E EA RS L P GVEAV F T WED VP DIP FPTAGHP 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 86 Y SLDP S HRDI E D YS LLT DKA R FV GDAVAAVVA N DEL I A K KALKLIKVEYE I LP FVM D Q E E A IK EGAP V IH DE R p N N IVSD 165
Cdd:PRK09970 81 W SLDP N HRDI A D RA LLT RHV R HH GDAVAAVVA R DEL T A E KALKLIKVEYE E LP VIT D P E A A LA EGAP P IH NG R - G N LLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 166 FGITV G DPDEVF K N AD KIYK G Q YET Q IVQHC Q ME THNAM A KIDEK GR ML I IT STQIPHIVRR I V SK A CNL P I G RI RVIKP 245
Cdd:PRK09970 160 STMST G NVQQTI K A AD YQVQ G H YET P IVQHC H ME NVTSY A YMEDD GR IT I VS STQIPHIVRR V V GQ A LGI P W G KV RVIKP 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 246 YVGGGFG G KQDV II EPL T A IMSLA V N GR C V RLQ LSREE AIVS TRTRHA MRVN IKM ALSKNNKIE GY DIENFV N N GAYASH 325
Cdd:PRK09970 240 YVGGGFG N KQDV LE EPL A A FLTSK V G GR P V KVS LSREE CFLA TRTRHA FTID IKM GVNRDGTLK GY SLDVLS N T GAYASH 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 326 GHSIA MSA G S K IRP LY DIK A E KY RP KT I YTNLP V AGAMR A YG I PQ MC F VI ESM V DD ICED L N IDPV D FR INSFIKK G HID 405
Cdd:PRK09970 320 GHSIA SAG G N K VAY LY PRC A Y KY SS KT V YTNLP S AGAMR G YG A PQ VV F AV ESM L DD AATA L G IDPV E FR LRNAARE G DAN 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 406 NA SG LVVRTF GLPECL KR GR ELID WD RK R QLY KNQ N G SI R K GVG M ACFSY F SGTWPV S LE A AGAR IV MNQDG S VQVQ V GA 485
Cdd:PRK09970 400 PL SG KRIYSA GLPECL EK GR KIFE WD KR R AEC KNQ Q G NL R R GVG V ACFSY T SGTWPV G LE I AGAR LL MNQDG T VQVQ S GA 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 486 TEIGQGSDTVFSQM A AET I GIP FDM V TIV S Q QDTD I TPFD T G S YASRQS FI AG Q AI K KAA I E V K R K V L EI A SDKCGLD A E 565
Cdd:PRK09970 480 TEIGQGSDTVFSQM V AET V GIP VSD V RVI S T QDTD V TPFD P G A YASRQS YV AG P AI R KAA L E L K E K I L AH A AVMLHQS A M 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 566 L LDI V D AK I IE K GLRREIYT LEE I A LE AYY NR E KYAP IT SDLTV K VKN N AI A Y G A TFV E VEVDI KTG K IKVLD I Y NVHDS 645
Cdd:PRK09970 560 N LDI I D GH I VV K RPGEPLMS LEE L A MD AYY HP E RGGQ IT AESSI K TTT N PP A F G C TFV D VEVDI ALC K VTINR I L NVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 646 G K ILN KK LAEGQVHGG VS M AL G F AL S E KF IIDEKTG SII N N NLL H YKL Q T I MD T P NIKCE FV NT Y D P T S S YG Q KSLGE NT 725
Cdd:PRK09970 640 G H ILN PL LAEGQVHGG MG M GI G W AL F E EM IIDEKTG VVR N P NLL D YKL P T M MD L P QLESA FV EI Y E P Q S A YG H KSLGE PP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 489586032 726 T ISPAPAIRNAVL N ATGVA F N K LPM DA Q TV FE K F RKV GLI 765
Cdd:PRK09970 720 I ISPAPAIRNAVL M ATGVA I N T LPM TP Q RL FE E F KEA GLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
1-761
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 828.33
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 1 MEDSYDL IGK S V N RVD AV AKVTG K A K Y CS D YFE P DS L VGM V L RSP Y AHA KV K N IDT KE A EN L E GV E AVLT YKNV P NT KF P 80
Cdd:COG1529 3 DPADFRI IGK P V P RVD GP AKVTG R A R Y TD D IRL P GM L YAA V V RSP H AHA RI K S IDT SA A LA L P GV V AVLT GEDL P GL KF G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 81 TA G H pysldpshr D IEDYS L LT DK A R F VG DA VAAVVA NDELI A KK A LK LIKVEYE I LP F V M D Q E E A IKE GAP VI H D E R P N 160
Cdd:COG1529 83 LP G P --------- D PDQPP L AD DK V R Y VG EP VAAVVA ETREA A RD A AE LIKVEYE P LP A V V D P E A A LAP GAP LV H E E L P G 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 161 N IVSDFGITV GD P D EV F KN AD KIYKGQ Y E T QIVQ H CQ ME THN A M A KI D EK GR MLIIT STQ I PH I VRR IVSK A CN LP IGRI 240
Cdd:COG1529 154 N VAAEWRGER GD V D AA F AE AD VVVEAT Y T T PRLA H AP ME PRA A V A EW D GD GR LTVWA STQ G PH L VRR ALAR A LG LP PEKV 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 241 RVI K P Y VGGGFGGK Q DV - II E P L T A IMSLAV n GR C V R L Q L S REE AIVSTRT RHA MRVNIKMALS K NN KI EGYDIENFVNN 319
Cdd:COG1529 234 RVI A P D VGGGFGGK L DV y PE E V L A A LAARKL - GR P V K L V L T REE DFLADTH RHA TVQRVRLGAD K DG KI TALRHDVVADT 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 320 GAYAS H G HSIAMSAGSKIRPL Y D I KAEKYRPKTI YTN L P VA GA M R AY G I PQ MC F VI ES MV D DIC E D L NI DPV DF R INSF I 399
Cdd:COG1529 313 GAYAS F G EAVLPLGATMATGP Y A I PNVRVEARAV YTN T P PT GA Y R GP G R PQ AA F AL ES AM D ELA E E L GM DPV EL R LRNL I 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 400 KK G HID n AS G LVVRTFG L P ECL KRGR E LID W DRK R QLYKNQNGSIRK G V G M A CFSYF SG TWP vsl EAAG AR IVM N Q DGSV 479
Cdd:COG1529 393 RP G DFP - PT G QPYDSGR L A ECL EKAA E AFG W GER R ARPAEARAGKLR G I G V A AYIEG SG GGG --- DPES AR VRL N P DGSV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 480 Q V QV GAT E IGQG SD TV FS Q M AAE TI G I P FDM V TI V s QQ DTD I TP FDT G SYA SR QSFIA G Q A IK KAA IEVKR K V LE I A SDK 559
Cdd:COG1529 469 T V YT GAT D IGQG HE TV LA Q I AAE EL G V P PED V RV V - LG DTD L TP YGG G TGG SR STAVG G S A VR KAA EKLRE K L LE L A AHL 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 560 C G L D A E L L DIV D AKIIEK G LRR eiy T L E E I A LE AYY N ---- REK Y A P I T sdltvkvk NNAIAY GA TFV EVEVD IK TG KIK 635
Cdd:COG1529 548 L G A D P E D L EFE D GRVRVP G RSV --- S L A E L A AA AYY G glea TGT Y D P P T -------- YPTYSF GA HVA EVEVD PE TG EVR 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 636 VL DIYN VHD S G KIL N KK L A EGQV H GGV SMAL G F AL S E KFII DE k T G SII N N N LLH Y KLQTIM D T P N I KCE FV N T Y DPT SS 715
Cdd:COG1529 617 VL RVVA VHD C G RVI N PL L V EGQV E GGV VQGI G Q AL Y E ELVY DE - D G QLL N A N FAD Y LVPRAA D V P E I EVI FV E T P DPT NP 695
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 489586032 716 Y G Q K SL GE NT TI SP APAI R NAV LN ATGV AFNK LP MDAQT V FEKF R K 761
Cdd:COG1529 696 L G A K GV GE PG TI GV APAI A NAV YD ATGV RIRD LP ITPEK V LAAL R E 741
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
423-700
8.17e-104
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 319.87
E-value: 8.17e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 423 RGR EL I D W D RK R QLYKNQ N - G SIRK G V G M A CFSYF SG TW P VS L EA AGA RIVM N Q DGSV Q V QV G A TE I GQG SD T VFS Q M AA 501
Cdd:pfam20256 1 KAL EL S D Y D ER R AEQAEF N r G NRKR G I G I A PYVEG SG LG P GA L NQ AGA LVRL N P DGSV T V YT G G TE M GQG LE T KLA Q I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 502 E TI GIP FDM V TI V s QQ DTD IT P FDT G SY ASR QSFIA G Q A IKK AA IEVKRKV L E IA SDKCGLDA E L L DIV D A K IIE KG LR R 581
Cdd:pfam20256 81 E AL GIP PED V RV V - EG DTD TV P NGG G TG ASR STDVG G N A VLL AA EKLRERL L K IA AHLLEASP E D L EFE D G K VYV KG DP R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 582 EI y T LE E I A LE AY YNR ------ EK Y A P ITSDLTVKVKNNAIA YGA TFV EVEVD IK TG KIK VL DIYN VHD S G KIL N KKLA E 655
Cdd:pfam20256 160 SV - T FA E L A AA AY GEG vglsat GF Y T P PDDETGQGPPFAYYP YGA HAA EVEVD PE TG EVR VL RYVA VHD C G RVI N PAIV E 238
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 489586032 656 GQ VH GG VSMAL G F AL S E KFII DE k T G SIINNN L LH YK LQ T IM D T P 700
Cdd:pfam20256 239 GQ IE GG FVQGI G L AL M E ELVY DE - D G QLLTAS L MD YK IP T AA D I P 282
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
1-740
1.63e-51
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 194.84
E-value: 1.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 1 M EDSY D L IG KSVNRVDA V AKV TG K A K YC S D YFEP D SLVGMV - LR S PY AHAK VKN ID TK EA EN L E GV EAVL T YKNVPN - TK 78
Cdd:TIGR02969 569 M QLPQ D P IG HPIMHLSG V KHA TG E A I YC D D MPAV D QELFLT f VT S SR AHAK IVS ID LS EA LS L P GV VDII T AEHLQD a NT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 79 F P T aghpysldpshrdie DYS L L TDK ARF VG DA V A AV V A ND E LI AK K A L K LI K VE Y EI L - P FVMDQ EEAI KEGA p VIHD E 157
Cdd:TIGR02969 649 F G T --------------- EKL L A TDK VHC VG QL V C AV I A DS E VQ AK Q A A K HV K IV Y RD L e P LILTI EEAI QHKS - FFEP E 712
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 158 R P nnivsdfg ITV G DP DE V FK NA D K I YK G QYETQIVQ H CQ MET HNAMA - KID E KGR M LIIT STQ I P HIVRR IV SKACN LP 236
Cdd:TIGR02969 713 R K -------- LEY G NV DE A FK VV D Q I LE G EIHMGGQE H FY MET QSMLV v PKG E DQE M DVYV STQ F P KYIQD IV AATLK LP 784
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 237 IGRIRVIKPY VGG G FGGK -- QDV I IEPL TA IMS l AVN GR C VR LQ L S R E E AIVS T RT RH AMRVNI K MALSKNNK I EGY D I E 314
Cdd:TIGR02969 785 VNKVMCHVRR VGG A FGGK vg KTS I MAAI TA FAA - NKH GR A VR CT L E R G E DMLI T GG RH PYLGKY K AGFMNDGR I VAL D V E 863
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 315 NFV N N G AYASHGHSIAMSAGS K IRPL Y DIKAEKY R PKTIY TNLP VAG A M R AY G I PQ MCFVI E SMVDDICEDLNID P VDF R 394
Cdd:TIGR02969 864 HYS N G G SSLDESLWVIEMGLL K MDNA Y KFPNLRC R GWACR TNLP SNT A F R GF G F PQ AGLIT E ACITEVAAKCGLS P EKV R 943
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 395 INSFI K K gh ID NAS - GLVVRTFG L PE C LKRGRELIDWDRKR --- QLYKNQ N GSIRK G VGMACFSYFS G TWP V SLEA A G A R 470
Cdd:TIGR02969 944 TINMY K E -- ID QTP y KQEINAKN L FQ C WRECMAKSSYSERK vav EKFNAE N YWKKR G LAVIPLKFPV G LGS V AMGQ A A A L 1021
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 471 IVMNQ DGSV Q V QV G AT E I GQG SD T VFS Q MAAETIGI P FDM V TI v SQQD T DIT P FDTG S YA S RQSFIA G Q A I K K A AIEVKR 550
Cdd:TIGR02969 1022 VHIYL DGSV L V TH G GI E M GQG VH T KMI Q VVSRELKM P MSN V HL - RGTS T ETV P NTNA S GG S VVADLN G L A V K D A CQTLLK 1100
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 551 KVLE I A S DK cgldaelldivdakii EK G LRREIYTL --- EE I A L E A Y - Y N R EKYAP I TSDLTVKVKNNAIA YGA TFV EVE 626
Cdd:TIGR02969 1101 RLEP I I S KN ---------------- PQ G TWKDWAQT afd QS I S L S A V g Y F R GYESN I NWEKGEGHPFEYFV YGA ACS EVE 1164
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 627 V D IK TG KI K VLDIYN V H D S G KIL N KK L AE GQV H G GVSMAL G FALS E KFIIDEK t G SIINNNLLH YK LQT I M D T P N ikc E F 706
Cdd:TIGR02969 1165 I D CL TG DH K NIRTDI V M D V G HSI N PA L DI GQV E G AFIQGM G LYTI E ELSYSPQ - G ILYSRGPNQ YK IPA I C D I P T --- E L 1240
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 489586032 707 VNTYD P T S S ----- Y GQ K S LGE NTTI --- S PAP AI RN AV LN A 740
Cdd:TIGR02969 1241 HISFL P P S E hsntl Y SS K G LGE SGVF lgc S VFF AI HD AV RA A 1282
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
22-138
5.75e-30
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 114.15
E-value: 5.75e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 22 TG K A K Y CS D YFE P DS L VGM V L RSP Y AHA KV K N IDT KE A ENLE GV E AVLT Y K N VP NTKFPTAGH P ysldpshrdi EDYS L L 101
Cdd:smart01008 1 TG E A R Y GD D IRL P GM L HAA V V RSP V AHA RI K S IDT SA A RAMP GV V AVLT A K D VP GLNDFGPLG P ---------- DEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 489586032 102 T DK A R F VG DA VAAVVA ND E LI A KK A LKLI KVEYE I LP 138
Cdd:smart01008 71 D DK V R Y VG QP VAAVVA ET E EA A RD A AEAV KVEYE E LP 107
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
6-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1389.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 6 DL IGKS VN RVDA V AKVTG K AKY CS DY FEPDS L VGMVL RSP Y AH A KVK N IDT K EA EN L E GVEAV L T YKN VP NTK FPTAGHP 85
Cdd:PRK09970 1 MA IGKS IM RVDA I AKVTG R AKY TD DY VMAGM L YAKYV RSP I AH G KVK S IDT E EA RS L P GVEAV F T WED VP DIP FPTAGHP 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 86 Y SLDP S HRDI E D YS LLT DKA R FV GDAVAAVVA N DEL I A K KALKLIKVEYE I LP FVM D Q E E A IK EGAP V IH DE R p N N IVSD 165
Cdd:PRK09970 81 W SLDP N HRDI A D RA LLT RHV R HH GDAVAAVVA R DEL T A E KALKLIKVEYE E LP VIT D P E A A LA EGAP P IH NG R - G N LLKQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 166 FGITV G DPDEVF K N AD KIYK G Q YET Q IVQHC Q ME THNAM A KIDEK GR ML I IT STQIPHIVRR I V SK A CNL P I G RI RVIKP 245
Cdd:PRK09970 160 STMST G NVQQTI K A AD YQVQ G H YET P IVQHC H ME NVTSY A YMEDD GR IT I VS STQIPHIVRR V V GQ A LGI P W G KV RVIKP 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 246 YVGGGFG G KQDV II EPL T A IMSLA V N GR C V RLQ LSREE AIVS TRTRHA MRVN IKM ALSKNNKIE GY DIENFV N N GAYASH 325
Cdd:PRK09970 240 YVGGGFG N KQDV LE EPL A A FLTSK V G GR P V KVS LSREE CFLA TRTRHA FTID IKM GVNRDGTLK GY SLDVLS N T GAYASH 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 326 GHSIA MSA G S K IRP LY DIK A E KY RP KT I YTNLP V AGAMR A YG I PQ MC F VI ESM V DD ICED L N IDPV D FR INSFIKK G HID 405
Cdd:PRK09970 320 GHSIA SAG G N K VAY LY PRC A Y KY SS KT V YTNLP S AGAMR G YG A PQ VV F AV ESM L DD AATA L G IDPV E FR LRNAARE G DAN 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 406 NA SG LVVRTF GLPECL KR GR ELID WD RK R QLY KNQ N G SI R K GVG M ACFSY F SGTWPV S LE A AGAR IV MNQDG S VQVQ V GA 485
Cdd:PRK09970 400 PL SG KRIYSA GLPECL EK GR KIFE WD KR R AEC KNQ Q G NL R R GVG V ACFSY T SGTWPV G LE I AGAR LL MNQDG T VQVQ S GA 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 486 TEIGQGSDTVFSQM A AET I GIP FDM V TIV S Q QDTD I TPFD T G S YASRQS FI AG Q AI K KAA I E V K R K V L EI A SDKCGLD A E 565
Cdd:PRK09970 480 TEIGQGSDTVFSQM V AET V GIP VSD V RVI S T QDTD V TPFD P G A YASRQS YV AG P AI R KAA L E L K E K I L AH A AVMLHQS A M 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 566 L LDI V D AK I IE K GLRREIYT LEE I A LE AYY NR E KYAP IT SDLTV K VKN N AI A Y G A TFV E VEVDI KTG K IKVLD I Y NVHDS 645
Cdd:PRK09970 560 N LDI I D GH I VV K RPGEPLMS LEE L A MD AYY HP E RGGQ IT AESSI K TTT N PP A F G C TFV D VEVDI ALC K VTINR I L NVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 646 G K ILN KK LAEGQVHGG VS M AL G F AL S E KF IIDEKTG SII N N NLL H YKL Q T I MD T P NIKCE FV NT Y D P T S S YG Q KSLGE NT 725
Cdd:PRK09970 640 G H ILN PL LAEGQVHGG MG M GI G W AL F E EM IIDEKTG VVR N P NLL D YKL P T M MD L P QLESA FV EI Y E P Q S A YG H KSLGE PP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 489586032 726 T ISPAPAIRNAVL N ATGVA F N K LPM DA Q TV FE K F RKV GLI 765
Cdd:PRK09970 720 I ISPAPAIRNAVL M ATGVA I N T LPM TP Q RL FE E F KEA GLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
1-761
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 828.33
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 1 MEDSYDL IGK S V N RVD AV AKVTG K A K Y CS D YFE P DS L VGM V L RSP Y AHA KV K N IDT KE A EN L E GV E AVLT YKNV P NT KF P 80
Cdd:COG1529 3 DPADFRI IGK P V P RVD GP AKVTG R A R Y TD D IRL P GM L YAA V V RSP H AHA RI K S IDT SA A LA L P GV V AVLT GEDL P GL KF G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 81 TA G H pysldpshr D IEDYS L LT DK A R F VG DA VAAVVA NDELI A KK A LK LIKVEYE I LP F V M D Q E E A IKE GAP VI H D E R P N 160
Cdd:COG1529 83 LP G P --------- D PDQPP L AD DK V R Y VG EP VAAVVA ETREA A RD A AE LIKVEYE P LP A V V D P E A A LAP GAP LV H E E L P G 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 161 N IVSDFGITV GD P D EV F KN AD KIYKGQ Y E T QIVQ H CQ ME THN A M A KI D EK GR MLIIT STQ I PH I VRR IVSK A CN LP IGRI 240
Cdd:COG1529 154 N VAAEWRGER GD V D AA F AE AD VVVEAT Y T T PRLA H AP ME PRA A V A EW D GD GR LTVWA STQ G PH L VRR ALAR A LG LP PEKV 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 241 RVI K P Y VGGGFGGK Q DV - II E P L T A IMSLAV n GR C V R L Q L S REE AIVSTRT RHA MRVNIKMALS K NN KI EGYDIENFVNN 319
Cdd:COG1529 234 RVI A P D VGGGFGGK L DV y PE E V L A A LAARKL - GR P V K L V L T REE DFLADTH RHA TVQRVRLGAD K DG KI TALRHDVVADT 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 320 GAYAS H G HSIAMSAGSKIRPL Y D I KAEKYRPKTI YTN L P VA GA M R AY G I PQ MC F VI ES MV D DIC E D L NI DPV DF R INSF I 399
Cdd:COG1529 313 GAYAS F G EAVLPLGATMATGP Y A I PNVRVEARAV YTN T P PT GA Y R GP G R PQ AA F AL ES AM D ELA E E L GM DPV EL R LRNL I 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 400 KK G HID n AS G LVVRTFG L P ECL KRGR E LID W DRK R QLYKNQNGSIRK G V G M A CFSYF SG TWP vsl EAAG AR IVM N Q DGSV 479
Cdd:COG1529 393 RP G DFP - PT G QPYDSGR L A ECL EKAA E AFG W GER R ARPAEARAGKLR G I G V A AYIEG SG GGG --- DPES AR VRL N P DGSV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 480 Q V QV GAT E IGQG SD TV FS Q M AAE TI G I P FDM V TI V s QQ DTD I TP FDT G SYA SR QSFIA G Q A IK KAA IEVKR K V LE I A SDK 559
Cdd:COG1529 469 T V YT GAT D IGQG HE TV LA Q I AAE EL G V P PED V RV V - LG DTD L TP YGG G TGG SR STAVG G S A VR KAA EKLRE K L LE L A AHL 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 560 C G L D A E L L DIV D AKIIEK G LRR eiy T L E E I A LE AYY N ---- REK Y A P I T sdltvkvk NNAIAY GA TFV EVEVD IK TG KIK 635
Cdd:COG1529 548 L G A D P E D L EFE D GRVRVP G RSV --- S L A E L A AA AYY G glea TGT Y D P P T -------- YPTYSF GA HVA EVEVD PE TG EVR 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 636 VL DIYN VHD S G KIL N KK L A EGQV H GGV SMAL G F AL S E KFII DE k T G SII N N N LLH Y KLQTIM D T P N I KCE FV N T Y DPT SS 715
Cdd:COG1529 617 VL RVVA VHD C G RVI N PL L V EGQV E GGV VQGI G Q AL Y E ELVY DE - D G QLL N A N FAD Y LVPRAA D V P E I EVI FV E T P DPT NP 695
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 489586032 716 Y G Q K SL GE NT TI SP APAI R NAV LN ATGV AFNK LP MDAQT V FEKF R K 761
Cdd:COG1529 696 L G A K GV GE PG TI GV APAI A NAV YD ATGV RIRD LP ITPEK V LAAL R E 741
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
3-762
1.61e-140
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 437.73
E-value: 1.61e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 3 D SYDL IGK SVNRV DA VAK V TG K AK Y CS D YFEP D SL V GMV LRSP Y AHA KVKNI D TKE AE N L E GV EA V L T YK N V P NTKFPTA 82
Cdd:PRK09800 167 D DLEV IGK HYPKT DA AKM V QA K PC Y VE D RVTA D AC V IKM LRSP H AHA LITHL D VSK AE A L P GV VH V I T HL N C P DIYYTPG 246
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 83 G HPYS l D PS HR D ied YSLLTD K A R F VGD A VAAVVA ND E L IA KK ALKLI K VEYE I L PF VM DQE EA IK E G APV I HDE ----- 157
Cdd:PRK09800 247 G QSAP - E PS PL D --- RRMFGK K M R H VGD R VAAVVA ES E E IA LE ALKLI D VEYE V L KP VM SID EA MA E D APV V HDE pvvyv 322
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 158 ---------------- R PNNIVSD F G I -------------- TV GD P D EV F KN AD K I YKGQ Y ETQIV Q H C QM ETH NAMAKI 207
Cdd:PRK09800 323 agapdtleddnshaaq R GEHMIIN F P I gsrprkniaasihg HI GD M D KG F AD AD V I IERT Y NSTQA Q Q C PT ETH ICFTRM 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 208 D EK g R ML I IT STQ I P HIV RR I V SKACNLPIGRIR VIK PY VGGGFG G KQD VII E PLT A i MSLA V N GR C V RLQLS REE AIVS 287
Cdd:PRK09800 403 D GD - R LV I HA STQ V P WHL RR Q V ARLVGMKQHKVH VIK ER VGGGFG S KQD ILL E EVC A - WATC V T GR P V LFRYT REE EFIA 480
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 288 TRT RH AMR V NI K MALS K NNKIEGYDIENFV N N G A Y AS H GHSIAMSAGSKIR PLY DIKAEKYRPK T I Y T N LPVA GA MRA YG 367
Cdd:PRK09800 481 NTS RH VAK V TV K LGAK K DGRLTAVKMDFRA N T G P Y GN H SLTVPCNGPALSL PLY PCDNVDFQVT T Y Y S N ICPN GA YQG YG 560
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 368 I P QMC F V I ESMVDDIC E D L N ID PVDFRINSFIKK G HIDNAS G LV ----------- VRTFG L P E C L KR GRE L I D W DRKRQ l 436
Cdd:PRK09800 561 A P KGN F A I TMALAELA E Q L Q ID QLEIIERNRVHE G QELKIL G AI gegkaptsvps AASCA L E E I L RQ GRE M I Q W SSPKP - 639
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 437 ykn QNG SIRK G V G M A CFSYF SG T w P v SLEA A GAR I VMNQ DG SVQ V QV G ATE IG Q G S DTV FSQM AAE TIGI P FDM V TIV S q 516
Cdd:PRK09800 640 --- QNG DWHI G R G V A IIMQK SG I - P - DIDQ A NCM I KLES DG TFI V HS G GAD IG T G L DTV VTKL AAE VLHC P PQD V HVI S - 713
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 517 Q DTD ITP FD T G S YAS RQSFIA G Q A IKK AA IEVKR K V L EIASDKC G LDAELLDIVDAKII e K G LRR E I y TLEE IA LEA --- 593
Cdd:PRK09800 714 G DTD HAL FD K G A YAS SGTCFS G N A ARL AA ENLRE K I L FHGAQML G EPVADVQLATPGVV - R G KKG E V - SFGD IA HKG etg 791
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 594 -- YYNREKYAP - IT S D L tvkvknn A IA YGA T F V EV E V DIK TG K I KVLDI Y NVH D S G KIL N KK LA E GQ VH G GVSM A L G FAL 670
Cdd:PRK09800 792 tg FGSLVGTGS y IT P D F ------- A FP YGA N F A EV A V NTR TG E I RLDKF Y ALL D C G TPV N PE LA L GQ IY G ATLR A I G HSM 864
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 671 SE KF I I D e KT G SIINNN L LH Y KLQT I M D T P - NIKCEF V NTY D PTSSY G Q KS LG E NTTISP APAI RN A VLN A T G VAFNKLP 749
Cdd:PRK09800 865 SE EI I Y D - AE G HPLTRD L RS Y GAPK I G D I P r DFRAVL V PSD D KVGPF G A KS IS E IGVNGA APAI AT A IHD A C G IWLREWH 943
810
....*....|...
gi 489586032 750 MDAQTVFEKFR K V 762
Cdd:PRK09800 944 FTPEKILTALE K I 956
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
423-700
8.17e-104
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 319.87
E-value: 8.17e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 423 RGR EL I D W D RK R QLYKNQ N - G SIRK G V G M A CFSYF SG TW P VS L EA AGA RIVM N Q DGSV Q V QV G A TE I GQG SD T VFS Q M AA 501
Cdd:pfam20256 1 KAL EL S D Y D ER R AEQAEF N r G NRKR G I G I A PYVEG SG LG P GA L NQ AGA LVRL N P DGSV T V YT G G TE M GQG LE T KLA Q I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 502 E TI GIP FDM V TI V s QQ DTD IT P FDT G SY ASR QSFIA G Q A IKK AA IEVKRKV L E IA SDKCGLDA E L L DIV D A K IIE KG LR R 581
Cdd:pfam20256 81 E AL GIP PED V RV V - EG DTD TV P NGG G TG ASR STDVG G N A VLL AA EKLRERL L K IA AHLLEASP E D L EFE D G K VYV KG DP R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 582 EI y T LE E I A LE AY YNR ------ EK Y A P ITSDLTVKVKNNAIA YGA TFV EVEVD IK TG KIK VL DIYN VHD S G KIL N KKLA E 655
Cdd:pfam20256 160 SV - T FA E L A AA AY GEG vglsat GF Y T P PDDETGQGPPFAYYP YGA HAA EVEVD PE TG EVR VL RYVA VHD C G RVI N PAIV E 238
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 489586032 656 GQ VH GG VSMAL G F AL S E KFII DE k T G SIINNN L LH YK LQ T IM D T P 700
Cdd:pfam20256 239 GQ IE GG FVQGI G L AL M E ELVY DE - D G QLLTAS L MD YK IP T AA D I P 282
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
154-394
3.65e-94
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 293.21
E-value: 3.65e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 154 I H D E R PNN IV sd F GITV GD PDEV F KN AD KIYK G Q Y E T QIVQ H CQ MET HN A M A KI D - E K GR MLIIT STQ I PH I VRR I V SKA 232
Cdd:pfam02738 1 L H E E P PNN VA -- F HREK GD VEAA F AE AD HVVE G E Y R T GRQE H FY MET RA A L A VP D d E D GR LTVYS STQ G PH L VRR L V ARV 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 233 CNL P IGRI RVI K P Y VGGGFGGK - Q DVII E P L T A IMSLAV n GR C V RLQ L S REE AIVS T RT RH AMRVNI K MALS K NN KI EGY 311
Cdd:pfam02738 79 LGI P ENKV RVI V P R VGGGFGGK t Q SYPE E A L A A LAARKT - GR P V KWV L D REE DMLA T GH RH PFLIKY K VGAD K DG KI LAL 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 312 D IENFVNN GAYA SHGHSIAMS A G S KIRPL Y D I KAEKYRPKTI YTN L P VA GA M R AY G I PQ MC F VI E SMV D DIC E D L NI DP V 391
Cdd:pfam02738 158 D VDLYADG GAYA DLSPAVPER A L S HLDGP Y K I PNVRVDGRAV YTN T P PN GA F R GF G R PQ GM F AL E RLM D ELA E E L GM DP L 237
...
gi 489586032 392 DF R 394
Cdd:pfam02738 238 EL R 240
PLN02906
PLN02906 xanthine dehydrogenase
8-700
6.85e-59
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 217.26
E-value: 6.85e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 8 I G KSVNRVD A VAK VTG K A K Y CS D Y - FE P DS L VGMVLR S PYA HA KVKN ID TK EA ENLE G VEAVLTY K N VP NTK fptaghpy 86
Cdd:PLN02906 565 V G QPEVHLS A ELQ VTG E A E Y AD D I p MP P NT L HAALVL S TKP HA RILS ID DS EA KSSP G FAGIFLA K D VP GDN -------- 636
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 87 SLD P SHR D I E DYS ll TD KARF VG DAVAA VVA NDELI AK K A LKLI KVEYE I LP FVMDQ EEAI KE G A pv I H der PN niv SDF 166
Cdd:PLN02906 637 MIG P VVH D E E LFA -- TD VVTC VG QVIGV VVA DTQEN AK A A ARKV KVEYE E LP AILSI EEAI EA G S -- F H --- PN --- TER 706
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 167 GITV GD PDEV F KN -- A D K I YK G QYETQIVQ H CQM E THNAMAKIDEK G RML - I I T STQ I P HIVRRI V SKACN LP IGRIRVI 243
Cdd:PLN02906 707 RLEK GD VELC F AS gq C D R I IE G EVQMGGQE H FYL E PNSSLVWTSDS G NEV h M I S STQ A P QKHQKY V AHVLG LP MSKVVCK 786
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 244 KPYV GGGFGGK Q -- DVI I EPLT A IMSLAV N g R C V R L Q L S R EEAIVS T RT RHA MRVNI K MALSKNN KI EGY D I E NF v NNG a 321
Cdd:PLN02906 787 TKRI GGGFGGK E tr SAF I AAAA A VPAYLL N - R P V K L T L D R DVDMMI T GQ RHA FLGKY K VGFTNEG KI LAL D L E IY - NNG - 863
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 322 yash G H S IAM S AGSKI R PL ------ Y D I KAEKYRPKTIY TN L P VAG A M R AY G I PQ MCFVI E SMVDD I CED LN ID P VDF R I 395
Cdd:PLN02906 864 ---- G N S LDL S GAVLE R AM fhsdnv Y E I PNVRIVGNVCF TN F P SNT A F R GF G G PQ GMLIT E NWIQR I AVE LN KS P EEI R E 939
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 396 NS F IKK G HIDNA s G L V VRTFG LP ECLKRGRELI D WDRK R Q --- LYKNQ N GSIRK GV G M A cfsyfsgtw P VSLEAAGARIV 472
Cdd:PLN02906 940 MN F QGE G SVTHY - G Q V LQHCT LP QLWDELKVSC D FLKR R E evd EFNAK N RWKKR GV A M V --------- P TKFGISFTTKF 1009
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 473 MNQ --------- DG S V Q V QV G AT E I GQG SD T VFS Q M AA ETIG IP FDM V t IV S QQD TD IT P FDTGSY AS RQ S FIA G Q A IKK 543
Cdd:PLN02906 1010 MNQ agalvhvyt DG T V L V TH G GV E M GQG LH T KVA Q V AA SAFN IP LSS V - FI S ETS TD KV P NASPTA AS AS S DMY G A A VLD 1088
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 544 A AIEV K RKVLEI AS dkcgldaelldivdakiiekgl RREIYTLE E IALEA Y YN R EKYAP ---- IT S D LT --- VKV K N N AI 616
Cdd:PLN02906 1089 A CEQI K ARMEPV AS ---------------------- KLNFSSFA E LVTAC Y FQ R IDLSA hgfy IT P D IG fdw KTG K G N PF 1146
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 617 A Y --- GA T F V EVE V D IK TG KIKVLDIYN V H D S G KIL N KKLAE GQ VH G GVSMA LG F - AL S E -------- K F I ide KT GS II 684
Cdd:PLN02906 1147 N Y fty GA A F A EVE I D TL TG DFHTRRVDI V M D L G YSI N PAIDI GQ IE G AFVQG LG W v AL E E lkwgdaah K W I --- RP GS LF 1223
730
....*....|....*.
gi 489586032 685 NNNLLH YK LQTIM D T P 700
Cdd:PLN02906 1224 TCGPGT YK IPSVN D I P 1239
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
1-740
1.63e-51
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 194.84
E-value: 1.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 1 M EDSY D L IG KSVNRVDA V AKV TG K A K YC S D YFEP D SLVGMV - LR S PY AHAK VKN ID TK EA EN L E GV EAVL T YKNVPN - TK 78
Cdd:TIGR02969 569 M QLPQ D P IG HPIMHLSG V KHA TG E A I YC D D MPAV D QELFLT f VT S SR AHAK IVS ID LS EA LS L P GV VDII T AEHLQD a NT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 79 F P T aghpysldpshrdie DYS L L TDK ARF VG DA V A AV V A ND E LI AK K A L K LI K VE Y EI L - P FVMDQ EEAI KEGA p VIHD E 157
Cdd:TIGR02969 649 F G T --------------- EKL L A TDK VHC VG QL V C AV I A DS E VQ AK Q A A K HV K IV Y RD L e P LILTI EEAI QHKS - FFEP E 712
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 158 R P nnivsdfg ITV G DP DE V FK NA D K I YK G QYETQIVQ H CQ MET HNAMA - KID E KGR M LIIT STQ I P HIVRR IV SKACN LP 236
Cdd:TIGR02969 713 R K -------- LEY G NV DE A FK VV D Q I LE G EIHMGGQE H FY MET QSMLV v PKG E DQE M DVYV STQ F P KYIQD IV AATLK LP 784
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 237 IGRIRVIKPY VGG G FGGK -- QDV I IEPL TA IMS l AVN GR C VR LQ L S R E E AIVS T RT RH AMRVNI K MALSKNNK I EGY D I E 314
Cdd:TIGR02969 785 VNKVMCHVRR VGG A FGGK vg KTS I MAAI TA FAA - NKH GR A VR CT L E R G E DMLI T GG RH PYLGKY K AGFMNDGR I VAL D V E 863
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 315 NFV N N G AYASHGHSIAMSAGS K IRPL Y DIKAEKY R PKTIY TNLP VAG A M R AY G I PQ MCFVI E SMVDDICEDLNID P VDF R 394
Cdd:TIGR02969 864 HYS N G G SSLDESLWVIEMGLL K MDNA Y KFPNLRC R GWACR TNLP SNT A F R GF G F PQ AGLIT E ACITEVAAKCGLS P EKV R 943
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 395 INSFI K K gh ID NAS - GLVVRTFG L PE C LKRGRELIDWDRKR --- QLYKNQ N GSIRK G VGMACFSYFS G TWP V SLEA A G A R 470
Cdd:TIGR02969 944 TINMY K E -- ID QTP y KQEINAKN L FQ C WRECMAKSSYSERK vav EKFNAE N YWKKR G LAVIPLKFPV G LGS V AMGQ A A A L 1021
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 471 IVMNQ DGSV Q V QV G AT E I GQG SD T VFS Q MAAETIGI P FDM V TI v SQQD T DIT P FDTG S YA S RQSFIA G Q A I K K A AIEVKR 550
Cdd:TIGR02969 1022 VHIYL DGSV L V TH G GI E M GQG VH T KMI Q VVSRELKM P MSN V HL - RGTS T ETV P NTNA S GG S VVADLN G L A V K D A CQTLLK 1100
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 551 KVLE I A S DK cgldaelldivdakii EK G LRREIYTL --- EE I A L E A Y - Y N R EKYAP I TSDLTVKVKNNAIA YGA TFV EVE 626
Cdd:TIGR02969 1101 RLEP I I S KN ---------------- PQ G TWKDWAQT afd QS I S L S A V g Y F R GYESN I NWEKGEGHPFEYFV YGA ACS EVE 1164
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 627 V D IK TG KI K VLDIYN V H D S G KIL N KK L AE GQV H G GVSMAL G FALS E KFIIDEK t G SIINNNLLH YK LQT I M D T P N ikc E F 706
Cdd:TIGR02969 1165 I D CL TG DH K NIRTDI V M D V G HSI N PA L DI GQV E G AFIQGM G LYTI E ELSYSPQ - G ILYSRGPNQ YK IPA I C D I P T --- E L 1240
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 489586032 707 VNTYD P T S S ----- Y GQ K S LGE NTTI --- S PAP AI RN AV LN A 740
Cdd:TIGR02969 1241 HISFL P P S E hsntl Y SS K G LGE SGVF lgc S VFF AI HD AV RA A 1282
PLN00192
PLN00192 aldehyde oxidase
3-699
1.52e-46
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 179.53
E-value: 1.52e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 3 DS Y DLI G KSVNR V D A VAKVT G K A K Y CS D YFE P - DS L V G MVLR S PYAH A K VK N I DT K EAENLE GV E AV L T Y K NV P N ----- 76
Cdd:PLN00192 574 NE Y HPV G EPIKK V G A ALQAS G E A V Y VD D IPS P k NC L Y G AFIY S TKPL A R VK G I KF K SNLVPQ GV L AV I T F K DI P K ggqni 653
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 77 - T K FPTAGH P YSL D PS hrdiedyslltdk A R FV G DAV A A VVA NDELI A KK A LK L IK VEY E --- IL P FVMDQ E E A I K ---- 148
Cdd:PLN00192 654 g S K TIFGPE P LFA D EV ------------- T R CA G QRI A L VVA DTQKH A DM A AN L AV VEY D ten LE P PILTV E D A V K rssl 720
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 149 - E GA P VIHDER pnnivsdfgit VGD PDEVFKN AD - KI YKGQYETQIVQHCQ MET HN A M A KI DE KGRMLIIT STQ I P HI V R 226
Cdd:PLN00192 721 f E VP P FLYPKP ----------- VGD ISKGMAE AD h KI LSAEIKLGSQYYFY MET QT A L A LP DE DNCIVVYS STQ C P EY V H 789
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 227 RIVSKACNL P IGRI RVI KPY VGGGFGGK qdviieplt A IM S LA V NGR C ---------- VR LQ L S R EEAIVSTRT RH A M RV 296
Cdd:PLN00192 790 SVIARCLGI P EHNV RVI TRR VGGGFGGK --------- A VK S MP V ATA C alaafklqrp VR MY L N R KTDMIMAGG RH P M KI 860
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 297 NIKMALSKNN KI EGYDIENFV N N G ay A S HGH S IA M SAGS k I RP L -- YD IK A EKYRP K TIY TNL PVAG AMRA Y G IP Q MCFV 374
Cdd:PLN00192 861 TYSVGFKSDG KI TALHLDILI N A G -- I S PDI S PI M PRNI - I GA L kk YD WG A LSFDI K VCK TNL SSRS AMRA P G EV Q GSYI 937
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 375 I E SMVDDICED L NI D p VD F -- R IN ---- SFI K KGH i DNAS G LVV r TFG LP ECLKRGRELIDWDRKRQLY K NQ N G S IR - K G 447
Cdd:PLN00192 938 A E AIIEHVAST L SM D - VD S vr K IN lhty ESL K LFY - GDSA G EPS - EYT LP SIWDKLASSSEFKQRTEMV K EF N R S NK w K K 1014
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 448 V G MACFSY fsg TWP V S L EAAGARIVMNQ DGS VQ V Q VG AT EIGQG SD T VFS QMAA -------- ETIGIPF D MVTIV s Q Q DT 519
Cdd:PLN00192 1015 R G ISRVPI --- VHE V M L RPTPGKVSILS DGS IA V E VG GI EIGQG LW T KVK QMAA fglgmikc DGGEDLL D KIRVI - Q S DT 1090
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 520 ditpfdtg SYASRQS F I AG QAIKKAAI E VK R KV leiasdk C GLDA E L L DIVDAKII E KGLRREIYT L EEI A LEAYY N REK 599
Cdd:PLN00192 1091 -------- LSMIQGG F T AG STTSESSC E AV R LC ------- C VILV E R L KPIKERLQ E QMGSVTWDM L ISQ A YMQSV N LSA 1155
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 600 YAPI T S D LTVKVKN N aia YGA TFV EVEVD IK TG KIKV L DIYNVH D S G KI LN KKLAE GQ VH G GVSMAL GF ALS E KFIIDEK 679
Cdd:PLN00192 1156 SSYY T P D PSSMEYL N --- YGA AVS EVEVD LL TG ETTI L RSDIIY D C G QS LN PAVDL GQ IE G AFVQGI GF FML E EYTTNSD 1232
730 740
....*....|....*....|
gi 489586032 680 t G SIINNNLLH YK LQ T I m DT 699
Cdd:PLN00192 1233 - G LVVTDGTWT YK IP T V - DT 1250
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
22-138
5.75e-30
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 114.15
E-value: 5.75e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 22 TG K A K Y CS D YFE P DS L VGM V L RSP Y AHA KV K N IDT KE A ENLE GV E AVLT Y K N VP NTKFPTAGH P ysldpshrdi EDYS L L 101
Cdd:smart01008 1 TG E A R Y GD D IRL P GM L HAA V V RSP V AHA RI K S IDT SA A RAMP GV V AVLT A K D VP GLNDFGPLG P ---------- DEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 489586032 102 T DK A R F VG DA VAAVVA ND E LI A KK A LKLI KVEYE I LP 138
Cdd:smart01008 71 D DK V R Y VG QP VAAVVA ET E EA A RD A AEAV KVEYE E LP 107
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
22-138
5.37e-26
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 102.70
E-value: 5.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489586032 22 TG K A K Y CS D YFE P DS L V G MVL RS PY AHAK VKN IDT KE A EN L E GV E AV L T Y K NV P NTKFPTAGH P ysldpshrdi E D YSLL 101
Cdd:pfam01315 1 TG E A V Y VD D IPA P GN L Y G AFV RS TI AHAK IVS IDT SA A LA L P GV V AV I T A K DL P GGNYNIGPI P ---------- L D PLFA 70
90 100 110
....*....|....*....|....*....|....*..
gi 489586032 102 TDK A R F VG DAV AAVVA N DE LI A KK A L KL I KVEYE I LP 138
Cdd:pfam01315 71 TDK V R H VG QPI AAVVA D DE ET A RR A A KL V KVEYE E LP 107
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
