|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
64-395 |
6.19e-83 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 257.18 E-value: 6.19e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 64 VITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEI 143
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 144 DFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTGGnagaaT 223
Cdd:COG0845 83 ELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAG-----T 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 224 LLTTIVATDPLYVYFDIDEATYLGFVANArapetgtvagklPVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVK 303
Cdd:COG0845 158 PLFTIADLDPLEVEFDVPESDLARLKVGQ------------PVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 304 NPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVK 383
Cdd:COG0845 226 NPDGLLRPGMFVRVRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVS 305
|
330
....*....|....
gi 489595759 384 GL--VRPGMQVVPQ 395
Cdd:COG0845 306 GLqrLRDGAKVRVV 319
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
59-395 |
1.48e-73 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 232.98 E-value: 1.48e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 59 VPVAEVITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLL 138
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 139 DQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTggn 218
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVT--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 219 agAATLLTTIVATDPLYVYFDIDEATYLGFVANArapetgtvagklPVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRA 298
Cdd:TIGR01730 158 --AGQTLATIVDLDPLEADFSVPERDLPQLRRGQ------------TLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRV 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 299 RAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPAD 378
Cdd:TIGR01730 224 RATFPNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGD 303
|
330
....*....|....*....
gi 489595759 379 KIIVKGLV--RPGMQVVPQ 395
Cdd:TIGR01730 304 QIVTAGVVklRDGAKVKVV 322
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
35-419 |
9.07e-58 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 194.55 E-value: 9.07e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 35 VLALASSTAASEAVAQPAQMPVPQVPVAEVITRKVAP---SVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGEL 111
Cdd:PRK15030 13 VLMLSGSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPlqiTTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 112 LFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLS 191
Cdd:PRK15030 93 LYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 192 FARVTAPIAGRIDRVLVTEGNLVTGGNAGAatlLTTIVATDPLYVyfDIDEATYlGFVANARAPETGTVA---GKLPVHL 268
Cdd:PRK15030 173 YTKVTSPISGRIGKSNVTEGALVQNGQATA---LATVQQLDPIYV--DVTQSSN-DFLRLKQELANGTLKqenGKAKVSL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 269 GLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIG-IDQGRRYVLAL 347
Cdd:PRK15030 247 ITSDGIKFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTrTPRGDATVLVV 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489595759 348 GADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVKGL--VRPGMQVVPQMIsmapgdTATDDRAAADSQEARQ 419
Cdd:PRK15030 327 GADDKVETRPIVASQAIGDKWLVTEGLKAGDRVVISGLqkVRPGVQVKAQEV------TADNNQQAASGAQPEQ 394
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
72-382 |
1.86e-35 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 132.93 E-value: 1.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 72 SVEFTGHLEA-TKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEA 150
Cdd:pfam00529 7 GVEAPGRVVVsGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 151 LASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVtggNAGAATLLTTIVA 230
Cdd:pfam00529 87 LESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALV---AQAQANLLATVAQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 231 TDPLYVYFDIDEATYLGFVANARAPETGTVAgKLPVHLGLMTDTG------FPHAGELDFLGNRVDRSTGTIRARAIVKN 304
Cdd:pfam00529 164 LDQIYVQITQSAAENQAEVRSELSGAQLQIA-EAEAELKLAKLDLerteirAPVDGTVAFLSVTVDGGTVSAGLRLMFVV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 305 P-DGRLTPGLFARVKLVTAEPAQTVLIDDQAIGID-QGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIV 382
Cdd:pfam00529 243 PeDNLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTkTGRFTGVVVGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVRL 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
64-395 |
6.19e-83 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 257.18 E-value: 6.19e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 64 VITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEI 143
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 144 DFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTGGnagaaT 223
Cdd:COG0845 83 ELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAG-----T 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 224 LLTTIVATDPLYVYFDIDEATYLGFVANArapetgtvagklPVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVK 303
Cdd:COG0845 158 PLFTIADLDPLEVEFDVPESDLARLKVGQ------------PVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 304 NPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVK 383
Cdd:COG0845 226 NPDGLLRPGMFVRVRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVS 305
|
330
....*....|....
gi 489595759 384 GL--VRPGMQVVPQ 395
Cdd:COG0845 306 GLqrLRDGAKVRVV 319
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
59-395 |
1.48e-73 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 232.98 E-value: 1.48e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 59 VPVAEVITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLL 138
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 139 DQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTggn 218
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVT--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 219 agAATLLTTIVATDPLYVYFDIDEATYLGFVANArapetgtvagklPVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRA 298
Cdd:TIGR01730 158 --AGQTLATIVDLDPLEADFSVPERDLPQLRRGQ------------TLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRV 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 299 RAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPAD 378
Cdd:TIGR01730 224 RATFPNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGD 303
|
330
....*....|....*....
gi 489595759 379 KIIVKGLV--RPGMQVVPQ 395
Cdd:TIGR01730 304 QIVTAGVVklRDGAKVKVV 322
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
35-419 |
9.07e-58 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 194.55 E-value: 9.07e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 35 VLALASSTAASEAVAQPAQMPVPQVPVAEVITRKVAP---SVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGEL 111
Cdd:PRK15030 13 VLMLSGSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPlqiTTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 112 LFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLS 191
Cdd:PRK15030 93 LYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 192 FARVTAPIAGRIDRVLVTEGNLVTGGNAGAatlLTTIVATDPLYVyfDIDEATYlGFVANARAPETGTVA---GKLPVHL 268
Cdd:PRK15030 173 YTKVTSPISGRIGKSNVTEGALVQNGQATA---LATVQQLDPIYV--DVTQSSN-DFLRLKQELANGTLKqenGKAKVSL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 269 GLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIG-IDQGRRYVLAL 347
Cdd:PRK15030 247 ITSDGIKFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTrTPRGDATVLVV 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489595759 348 GADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVKGL--VRPGMQVVPQMIsmapgdTATDDRAAADSQEARQ 419
Cdd:PRK15030 327 GADDKVETRPIVASQAIGDKWLVTEGLKAGDRVVISGLqkVRPGVQVKAQEV------TADNNQQAASGAQPEQ 394
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
42-409 |
1.31e-50 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 175.29 E-value: 1.31e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 42 TAASEAVAQPAQMPVPQVPVAEVITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFE 121
Cdd:PRK09859 19 TACDDKSAENAAAMTPEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 122 VVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAG 201
Cdd:PRK09859 99 AELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPITG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 202 RIDRVLVTEGNLVTGGNAGAatlLTTIVATDPLYVYFDIDEATYLGFVANARAPETGTVAGKLPVHLGLMTDTGFPHAGE 281
Cdd:PRK09859 179 VSGKSSVTVGALVTANQADS---LVTVQRLDPIYVDLTQSVQDFLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGT 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 282 LDFLGNRVDRSTGTIRARAIVKNPDGRLTPGLFArVKLVTAEPAQTVLIDDQAiGID---QGRRYVLALGADNKAEYRPV 358
Cdd:PRK09859 256 LKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYV-TALVDEGSRQNVLLVPQE-GVThnaQGKATALILDKDDVVQLREI 333
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 489595759 359 EIGPMIDGLRVVAAGLKPADKIIVKGL--VRPGMQVvpQMISMAPGDTATDDR 409
Cdd:PRK09859 334 EASKAIGDQWVVTSGLQAGDRVIVSGLqrIRPGIKA--RAISSSQENASTESK 384
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
33-394 |
2.64e-44 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 158.42 E-value: 2.64e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 33 KSVLALASSTAAS-EAVAQPAQMPvPQVPVAEVITRKVAP---SVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRP 108
Cdd:PRK09578 9 LLLAALVALFVLAgCGKGDSDAAA-AAPREATVVTVRPTSvpmTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 109 GELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAEL 188
Cdd:PRK09578 88 GAVLFRIDPAPLKAARDAAAGALAKAEAAHLAALDKRRRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKAELARAQL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 189 DLSFARVTAPIAGRIDRVLVTEGNLVtggNAGAATLLTTIVATDPLYVYFDIDEATYLgfvANARAPETGTVAGK----L 264
Cdd:PRK09578 168 QLDYATVTAPIDGRARRALVTEGALV---GQDQATPLTTVEQLDPIYVNFSQPAADVE---ALRRAVKSGRATGIaqqdV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 265 PVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQGRRYV 344
Cdd:PRK09578 242 AVTLVRADGSEYPLKGKLLFSDLAVDPTTDTVAMRALFPNPERELLPGAYVRIALDRAVNPRAILVPRDALLRTADSASV 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 489595759 345 LALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVK--GLVRPGMQVVP 394
Cdd:PRK09578 322 KVVGQNGKVRDVEVEADQMSGRDWIVTRGLAGGERVIVDnaAQFAPGTAVKA 373
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
2-412 |
9.90e-42 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 152.25 E-value: 9.90e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 2 SNKAAALFLAGAVIAGGTLAIVYRDEIGPYAKSvlALASSTAASEAVAQPAQM---PVPQVPVAEVITRKVAPSVEFTGH 78
Cdd:PRK11556 4 SRKSRWVIVIVVVIAAIAAFWFWQGRSTSSSAA--PGAAKQAQQSPAGGRRGMrsgPLAPVQAATATEQAVPRYLTGLGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 79 LEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNAP 158
Cdd:PRK11556 82 VTAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQLAKDQATLANARRDLARYQQLAKTNLVS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 159 RKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTGGNagaATLLTTIVATDPLYVYF 238
Cdd:PRK11556 162 RQELDAQQALVSETEGTIKADEASVASAQLQLDYSRITAPISGRVGLKQVDVGNQISSGD---TTGIVVITQTHPIDLVF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 239 DIDEATYLGFVanaRAPETGTvagKLPVHLGLMTDTGFPHAGELDFLGNRVDRSTGTIRARAIVKNPDGRLTPGLF--AR 316
Cdd:PRK11556 239 TLPESDIATVV---QAQKAGK---PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKLKARFNNQDDALFPNQFvnAR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 317 VKLVTAEPAqtVLIDDQAIGIDQGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIVKGLVR--PGMQV-- 392
Cdd:PRK11556 313 MLVDTLQNA--VVIPTAALQMGNEGHFVWVLNDENKVSKHLVTPGIQDSQKVVISAGLSAGDRVVTDGIDRltEGAKVev 390
|
410 420
....*....|....*....|
gi 489595759 393 VPQMISMAPGDTATDDRAAA 412
Cdd:PRK11556 391 VEPQSATTPEEKATSREYAK 410
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
72-382 |
1.86e-35 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 132.93 E-value: 1.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 72 SVEFTGHLEA-TKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEA 150
Cdd:pfam00529 7 GVEAPGRVVVsGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 151 LASNGNAPRKAFDDALAMRRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVtggNAGAATLLTTIVA 230
Cdd:pfam00529 87 LESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALV---AQAQANLLATVAQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 231 TDPLYVYFDIDEATYLGFVANARAPETGTVAgKLPVHLGLMTDTG------FPHAGELDFLGNRVDRSTGTIRARAIVKN 304
Cdd:pfam00529 164 LDQIYVQITQSAAENQAEVRSELSGAQLQIA-EAEAELKLAKLDLerteirAPVDGTVAFLSVTVDGGTVSAGLRLMFVV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 305 P-DGRLTPGLFARVKLVTAEPAQTVLIDDQAIGID-QGRRYVLALGADNKAEYRPVEIGPMIDGLRVVAAGLKPADKIIV 382
Cdd:pfam00529 243 PeDNLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTkTGRFTGVVVGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVRL 322
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
85-321 |
2.14e-19 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 88.57 E-value: 2.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 85 IELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQAN---------------------------VL 137
Cdd:COG1566 46 VTVAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQAALAQAEAQLAAAEaqlarleaelgaeaeiaaaeaqlaaaqAQ 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 138 LDQAEIDFGRTEALASNGNAPRKAFDDA---------------------------LAMRRQRQAQVDIAKVAVSAAELDL 190
Cdd:COG1566 126 LDLAQRELERYQALYKKGAVSQQELDEAraaldaaqaqleaaqaqlaqaqaglreEEELAAAQAQVAQAEAALAQAELNL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 191 SFARVTAPIAGRIDRVLVTEGNLVTGGnagaaTLLTTIVATDPLYVYFDIDEaTYLGFVAnarapeTGTvagklPVHLGL 270
Cdd:COG1566 206 ARTTIRAPVDGVVTNLNVEPGEVVSAG-----QPLLTIVPLDDLWVEAYVPE-TDLGRVK------PGQ-----PVEVRV 268
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489595759 271 MTDTGFPHAGELDFLGNRVDRSTG----------TIRARAIVKNPDG-RLTPGLFARVKLVT 321
Cdd:COG1566 269 DAYPDRVFEGKVTSISPGAGFTSPpknatgnvvqRYPVRIRLDNPDPePLRPGMSATVEIDT 330
|
|
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
55-382 |
2.97e-15 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 76.74 E-value: 2.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 55 PVPQVPVAEVITRKVAPSVEFTGHLEATKAIELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRP-------FEVVLNAA 127
Cdd:PRK11578 32 PVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQaenqikeVEATLMEL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 128 KAQLQQANVLLDQAEIDFGRTEALASNGNAPRKAFDDA---LAMRRQR----QAQVDIAKVAVSAAELDLSFARVTAPIA 200
Cdd:PRK11578 112 RAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAateLAVKQAQigtiDAQIKRNQASLDTAKTNLDYTRIVAPMA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 201 GRIDRVLVTEGNLVTGgnAGAATLLTTIVATDPLYVYFDIDEATYLGFVANARApeTGTVAGklpvhlglmtDTGFPHAG 280
Cdd:PRK11578 192 GEVTQITTLQGQTVIA--AQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKA--WFTVLG----------DPLTRYEG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 281 ELDFLGNRVDRSTGTI--RARAIVKNPDGRLTPGLFARVKLVTAEPAQTVLIDDQAIGIDQG-RRYVLALGADNKAEYRP 357
Cdd:PRK11578 258 VLKDILPTPEKVNDAIfyYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGdNRYKVKLLRNGETRERE 337
|
330 340
....*....|....*....|....*
gi 489595759 358 VEIGPMIDGLRVVAAGLKPADKIIV 382
Cdd:PRK11578 338 VTIGARNDTDVEIVKGLEAGDEVII 362
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
89-301 |
1.67e-13 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 71.21 E-value: 1.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 89 PRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQ----------------------------QANVLLDQ 140
Cdd:PRK10476 53 SEVGGRIVELAVTENQAVKKGDLLFRIDPRPYELTVAQAQADLAladaqimttqrsvdaersnaasaneqveRARANAKL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 141 AEIDFGRTEALASNGNAPRKAFDDA------------LAMRRQRQ------------AQVDIAKVAVSAAELDLSFARVT 196
Cdd:PRK10476 133 ATRTLERLEPLLAKGYVSAQQVDQArtaqrdaevslnQALLQAQAaaaavggvdalvAQRAAREAALAIAELHLEDTTVR 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 197 APIAGRIDRVLVTEGNLVTggnagAATLLTTIVATDPLYVyfdideatylgfVANARAPETGTVAGKLPVHLGLMTDTGF 276
Cdd:PRK10476 213 APFDGRVVGLKVSVGEFAA-----PMQPIFTLIDTDHWYA------------IANFRETDLKNIRVGDCATVYSMIDRGR 275
|
250 260
....*....|....*....|....*
gi 489595759 277 PHAGELDFLGNRVDRSTGTIRARAI 301
Cdd:PRK10476 276 PFEGKVDSIGWGVLPDDGGNVPRGL 300
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
90-242 |
4.47e-09 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 57.66 E-value: 4.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 90 RVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQ--------------------------QANVLLDQAEI 143
Cdd:PRK03598 49 RVGGRLASLAVDEGDAVKAGQVLGELDAAPYENALMQAKANVSvaqaqldlmlagyrdeeiaqaraavkQAQAAYDYAQN 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 144 DFGRTEALASNGNAPRKAFDDALAMRRQRQAQVDIAK--------------------------VAVSAAELDLSFARVTA 197
Cdd:PRK03598 129 FYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQdklsqyregnrpqdiaqakaslaqaqAALAQAELNLQDTELIA 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 489595759 198 PIAGRIDRVLVTEGNLVTGGNAgaatlLTTIVATDPLYVYFDIDE 242
Cdd:PRK03598 209 PSDGTILTRAVEPGTMLNAGST-----VFTLSLTRPVWVRAYVDE 248
|
|
| PRK09783 |
PRK09783 |
copper/silver efflux system membrane fusion protein CusB; Provisional |
289-385 |
4.49e-07 |
|
copper/silver efflux system membrane fusion protein CusB; Provisional
Pssm-ID: 236625 [Multi-domain] Cd Length: 409 Bit Score: 51.79 E-value: 4.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 289 VDRSTGTIRARAIVKNPDGRLTPGLFARVKLVTAEpAQTVLIDDQAIgIDQGR-RYVLALGADNKAEYRPVEIGPMIDGL 367
Cdd:PRK09783 289 VDAATRTLQLRLEVDNADEALKPGMNAWLQLNTAS-EPMLLIPSQAL-IDTGSeQRVITVDADGRFVPKRVAVFQESQGV 366
|
90
....*....|....*...
gi 489595759 368 RVVAAGLKPADKIIVKGL 385
Cdd:PRK09783 367 TAIRSGLAEGEKVVSSGL 384
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
89-315 |
8.38e-07 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 49.43 E-value: 8.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 89 PRVGGAIVAASV-PEGGLVRPGELLFQI-------------------DPRPFEVVLNAAKAQLQQANVllDQAEIDfgrt 148
Cdd:pfam16576 24 ARVEGWIEKLYVnATGDPVKKGQPLAELyspelvaaqqeyllalrsgDALSKSELLRAARQRLRLLGM--PEAQIA---- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 149 ealasngnaprkafddalAMRRQRQAQVDIAkvavsaaeldlsfarVTAPIAGRIDRVLVTEGNLVTggnagAATLLTTI 228
Cdd:pfam16576 98 ------------------ELERTGKVQPTVT---------------VYAPISGVVTELNVREGMYVQ-----PGDTLFTI 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 229 VATDPLYVYFDIDEAtYLGFVAnarapeTGTVAgklpvhlgLMTDTGFPH---AGELDFLGNRVDRSTGTIRARAIVKNP 305
Cdd:pfam16576 140 ADLSTVWVEADVPEQ-DLALVK------VGQPA--------EVTLPALPGktfEGKVDYIYPTLDPKTRTVRVRIELPNP 204
|
250
....*....|
gi 489595759 306 DGRLTPGLFA 315
Cdd:pfam16576 205 DGRLKPGMFA 214
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
85-132 |
1.20e-05 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 42.43 E-value: 1.20e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 489595759 85 IELRPRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQ 132
Cdd:pfam13533 3 VKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQLA 50
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
194-312 |
5.25e-05 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 41.96 E-value: 5.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 194 RVTAPIAGRIDRVLVTEGNLVTGGnagaaTLLTTIVATDPLYVYFDIDEAtylgfvanarapETGTVAGKLPVHLGLMTD 273
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQVVQAG-----DPLATIVPPDRLLVEAFVPAA------------DLGSLKKGQKVTLKLDPG 63
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 489595759 274 TGFPHAGELDFLGNRVDRSTGTIRARAIVKNPDG--RLTPG 312
Cdd:pfam13437 64 SDYTLEGKVVRISPTVDPDTGVIPVRVSIENPKTpiPLLPG 104
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
89-236 |
5.34e-04 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 41.65 E-value: 5.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595759 89 PRVGGAIVAASVPEGGLVRPGELLFQIDPRPFEVVLNAAKAQLQQANVLLDQAEIDFGRTEALASNGNApRKAFDDALAM 168
Cdd:PRK10559 52 PDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRREAGRRNRLGVQAMS-REEIDQANNV 130
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489595759 169 RRQRQAQVDIAKVAVSAAELDLSFARVTAPIAGRIDRVLVTEGNLVTGGNAGAAtllttIVATDPLYV 236
Cdd:PRK10559 131 LQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVA-----LVKQNSFYV 193
|
|
| |
