|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1044 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1195.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 1 MNIPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 81 SSQAaTDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDnrYDPVYLSNFA 160
Cdd:COG0841 81 TSTS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 161 TLQVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQpeasaAFQVTVNTLG 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGG-----DREYTVRTNG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 241 RLSSEQQFGEIVVKTGtDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFP 320
Cdd:COG0841 233 RLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 321 EGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGL 400
Cdd:COG0841 312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 401 VLSIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:COG0841 392 VLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHGDVKrdlltrvidflfGWFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:COG0841 472 ISLFVALTLTPALCARLLKPHPKGKK------------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNGmvNIPNAAVMFTML 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGG--SGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 641 KPFDERKdpsLSAFAIAGKLMGKFSQIPDGFAGIFPPPPvPGLGSTGGFKIQIEdraGLGFEALAQAQGAVMGRAMQTPE 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 721 LAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKVR 800
Cdd:COG0841 691 LVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVR 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 801 NATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGMAFEWTDLAYQEKQAG 879
Cdd:COG0841 771 TPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESF 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 880 DTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR 959
Cdd:COG0841 851 SSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFAN 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 960 AKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVRR 1039
Cdd:COG0841 931 QLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDR 1010
|
....*
gi 489595762 1040 LAIRR 1044
Cdd:COG0841 1011 LRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1038 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1106.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 83 QAAtDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATL 162
Cdd:pfam00873 81 QSS-YGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGS-VGQQpeasaaFQVTVNTLGR 241
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQlEGQG------LQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 242 LSSEQQFGEIVVKtGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPE 321
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 322 GIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLV 401
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 402 LSIGIVVDDAIVVVENVERHIAL-GETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHgdvKRDLltrvidflfGWFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRR---EPKH---------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVG 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNGMVNIPNAAVMFTML 640
Cdd:pfam00873 541 SVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISL 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 641 KPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIED-RAGLGFEALAQAQGAVMGRAMQTP 719
Cdd:pfam00873 621 KPWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLP 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 720 ELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKV 799
Cdd:pfam00873 701 GLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYV 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 800 RNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGMAFEWTDLAYQEKQA 878
Cdd:pfam00873 781 RNPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQLA 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 879 GDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA 958
Cdd:pfam00873 861 GNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFA 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 959 RAK-EDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVV 1037
Cdd:pfam00873 941 NELrEQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
|
.
gi 489595762 1038 R 1038
Cdd:pfam00873 1021 H 1021
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1054 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1095.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 83 QAATDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEASA-AFQVTVNTLGR 241
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGqQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 242 LSSEQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPE 321
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 322 GIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLV 401
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 402 LSIGIVVDDAIVVVENVERHIAL-GETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMAEeGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHGDVKRDLLTRvidfLFGWFfrlfNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPIEKGEHHEKKGG----FFGWF----NRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGG 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPG--VESVVAFPGLSVNGmvNIPNAAVMFT 638
Cdd:TIGR00915 552 MVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAG--RGQNMGMAFI 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 639 MLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAMQT 718
Cdd:TIGR00915 630 RLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQN 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 719 PELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLK 798
Cdd:TIGR00915 710 PALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWY 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 799 VRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASEtLPAGMAFEWTDLAYQEKQA 878
Cdd:TIGR00915 790 VRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLS 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 879 GDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA 958
Cdd:TIGR00915 869 GSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFA 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 959 RAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVR 1038
Cdd:TIGR00915 949 KELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVR 1028
|
1050
....*....|....*.
gi 489595762 1039 RLAIRRSASPQQATEV 1054
Cdd:TIGR00915 1029 RLFKRKAHEKEMSVEH 1044
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
6-1039 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 877.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 6 FFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQAA 85
Cdd:PRK10555 4 FFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 86 TDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATLQVR 165
Cdd:PRK10555 84 GTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 166 DQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEA-SAAFQVTVNTLGRLSS 244
Cdd:PRK10555 164 DPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVdKQALNATINAQSLLQT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 245 EQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEGIE 324
Cdd:PRK10555 243 PEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 325 YRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSI 404
Cdd:PRK10555 323 YKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 405 GIVVDDAIVVVENVERHIA-LGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTILSA 483
Cdd:PRK10555 403 GLLVDDAIVVVENVERIMSeEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 484 INSLTLSPALAGVLLKP-----HHGdvKRDlltrvidfLFGWFFRLFNRffdgASTAYVWSVRRAARLSVLVLLVYAGLV 558
Cdd:PRK10555 483 LVAMILTPALCATLLKPlkkgeHHG--QKG--------FFGWFNRMFNR----NAERYEKGVAKILHRSLRWILIYVLLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 559 GMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPG--VESVVAFPGLSVNGmvNIPNAAVM 636
Cdd:PRK10555 549 GGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKdnVMSVFATVGSGPGG--NGQNVARM 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 637 FTMLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAM 716
Cdd:PRK10555 627 FIRLKDWDERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 717 QTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGR 796
Cdd:PRK10555 707 KNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINL 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 797 LKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASEtLPAGMAFEWTDLAYQEK 876
Cdd:PRK10555 787 WYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ-LPNGFGLEWTAMSYQER 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 877 QAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVE 956
Cdd:PRK10555 866 LSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVE 945
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 957 FARAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVV 1036
Cdd:PRK10555 946 FANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVL 1025
|
...
gi 489595762 1037 VRR 1039
Cdd:PRK10555 1026 VRR 1028
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1039 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 742.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 5 RFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQA 84
Cdd:NF033617 2 DVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 85 ATdGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVqRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATLQV 164
Cdd:NF033617 82 SL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEA-PDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 165 RDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQpeaSAAFQVTVNTlgRLSS 244
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGD---SVVSTVRAND--QLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 245 EQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEGIE 324
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 325 YRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSI 404
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 405 GIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTILSAI 484
Cdd:NF033617 395 GLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGI 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 485 NSLTLSPALAGVLLKPHHGDVKrdlltrvidflfgwFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGMTWVG 564
Cdd:NF033617 475 VALTLTPMMCSRLLKANEKPGR--------------FARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 565 FQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLsvnGMVNIPNAAVMFTMLKPFD 644
Cdd:NF033617 541 YVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGV---GGNPGDNTGFGIINLKPWD 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 645 ERKDpslSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGlGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAMQTPELAGM 724
Cdd:NF033617 618 ERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADV 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 725 LASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKVRNATG 804
Cdd:NF033617 694 DSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 805 NMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASETLPAGMAFEWTDLAYQEKQAGDTAMY 884
Cdd:NF033617 774 KLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLF 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 885 VFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA-RAKED 963
Cdd:NF033617 854 LFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFAnELQRH 933
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489595762 964 EGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVRR 1039
Cdd:NF033617 934 QGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1044 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1195.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 1 MNIPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 81 SSQAaTDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDnrYDPVYLSNFA 160
Cdd:COG0841 81 TSTS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 161 TLQVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQpeasaAFQVTVNTLG 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGG-----DREYTVRTNG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 241 RLSSEQQFGEIVVKTGtDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFP 320
Cdd:COG0841 233 RLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 321 EGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGL 400
Cdd:COG0841 312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 401 VLSIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:COG0841 392 VLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHGDVKrdlltrvidflfGWFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:COG0841 472 ISLFVALTLTPALCARLLKPHPKGKK------------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNGmvNIPNAAVMFTML 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGG--SGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 641 KPFDERKdpsLSAFAIAGKLMGKFSQIPDGFAGIFPPPPvPGLGSTGGFKIQIEdraGLGFEALAQAQGAVMGRAMQTPE 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 721 LAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKVR 800
Cdd:COG0841 691 LVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVR 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 801 NATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGMAFEWTDLAYQEKQAG 879
Cdd:COG0841 771 TPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESF 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 880 DTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR 959
Cdd:COG0841 851 SSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFAN 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 960 AKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVRR 1039
Cdd:COG0841 931 QLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDR 1010
|
....*
gi 489595762 1040 LAIRR 1044
Cdd:COG0841 1011 LRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1038 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1106.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 83 QAAtDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATL 162
Cdd:pfam00873 81 QSS-YGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGS-VGQQpeasaaFQVTVNTLGR 241
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQlEGQG------LQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 242 LSSEQQFGEIVVKtGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPE 321
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 322 GIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLV 401
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 402 LSIGIVVDDAIVVVENVERHIAL-GETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHgdvKRDLltrvidflfGWFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRR---EPKH---------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVG 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNGMVNIPNAAVMFTML 640
Cdd:pfam00873 541 SVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISL 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 641 KPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIED-RAGLGFEALAQAQGAVMGRAMQTP 719
Cdd:pfam00873 621 KPWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLP 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 720 ELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKV 799
Cdd:pfam00873 701 GLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYV 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 800 RNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGMAFEWTDLAYQEKQA 878
Cdd:pfam00873 781 RNPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQLA 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 879 GDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA 958
Cdd:pfam00873 861 GNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFA 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 959 RAK-EDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVV 1037
Cdd:pfam00873 941 NELrEQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
|
.
gi 489595762 1038 R 1038
Cdd:pfam00873 1021 H 1021
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1054 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1095.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 83 QAATDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEASA-AFQVTVNTLGR 241
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGqQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 242 LSSEQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPE 321
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 322 GIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLV 401
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 402 LSIGIVVDDAIVVVENVERHIAL-GETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMAEeGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKPHHGDVKRDLLTRvidfLFGWFfrlfNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGM 560
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPIEKGEHHEKKGG----FFGWF----NRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGG 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 561 TWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPG--VESVVAFPGLSVNGmvNIPNAAVMFT 638
Cdd:TIGR00915 552 MVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAG--RGQNMGMAFI 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 639 MLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAMQT 718
Cdd:TIGR00915 630 RLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQN 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 719 PELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLK 798
Cdd:TIGR00915 710 PALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWY 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 799 VRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASEtLPAGMAFEWTDLAYQEKQA 878
Cdd:TIGR00915 790 VRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLS 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 879 GDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA 958
Cdd:TIGR00915 869 GSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFA 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 959 RAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVR 1038
Cdd:TIGR00915 949 KELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVR 1028
|
1050
....*....|....*.
gi 489595762 1039 RLAIRRSASPQQATEV 1054
Cdd:TIGR00915 1029 RLFKRKAHEKEMSVEH 1044
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
6-1039 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 877.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 6 FFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQAA 85
Cdd:PRK10555 4 FFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 86 TDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATLQVR 165
Cdd:PRK10555 84 GTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 166 DQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEA-SAAFQVTVNTLGRLSS 244
Cdd:PRK10555 164 DPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVdKQALNATINAQSLLQT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 245 EQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEGIE 324
Cdd:PRK10555 243 PEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 325 YRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSI 404
Cdd:PRK10555 323 YKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 405 GIVVDDAIVVVENVERHIA-LGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTILSA 483
Cdd:PRK10555 403 GLLVDDAIVVVENVERIMSeEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 484 INSLTLSPALAGVLLKP-----HHGdvKRDlltrvidfLFGWFFRLFNRffdgASTAYVWSVRRAARLSVLVLLVYAGLV 558
Cdd:PRK10555 483 LVAMILTPALCATLLKPlkkgeHHG--QKG--------FFGWFNRMFNR----NAERYEKGVAKILHRSLRWILIYVLLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 559 GMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPG--VESVVAFPGLSVNGmvNIPNAAVM 636
Cdd:PRK10555 549 GGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKdnVMSVFATVGSGPGG--NGQNVARM 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 637 FTMLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAM 716
Cdd:PRK10555 627 FIRLKDWDERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 717 QTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGR 796
Cdd:PRK10555 707 KNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINL 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 797 LKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASEtLPAGMAFEWTDLAYQEK 876
Cdd:PRK10555 787 WYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ-LPNGFGLEWTAMSYQER 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 877 QAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVE 956
Cdd:PRK10555 866 LSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVE 945
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 957 FARAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVV 1036
Cdd:PRK10555 946 FANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVL 1025
|
...
gi 489595762 1037 VRR 1039
Cdd:PRK10555 1026 VRR 1028
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
3-1054 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 873.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSS 82
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 83 QAATDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATL 162
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEASAA-FQVTVNTLGR 241
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQqLNASIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 242 LSSEQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPE 321
Cdd:PRK15127 240 LTSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 322 GIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLV 401
Cdd:PRK15127 320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 402 LSIGIVVDDAIVVVENVERHIA-LGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTI 480
Cdd:PRK15127 400 LAIGLLVDDAIVVVENVERVMAeEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 481 LSAINSLTLSPALAGVLLKP----HHGDVKRDlltrvidfLFGWffrlFNRFFDGASTAYVWSV----RRAARLSVLVLL 552
Cdd:PRK15127 480 LSVLVALILTPALCATMLKPiakgDHGEGKKG--------FFGW----FNRMFEKSTHHYTDSVgnilRSTGRYLVLYLI 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 553 VyagLVGMTWVgFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEP--GVESVVAFPGLSVNGmvNI 630
Cdd:PRK15127 548 I---VVGMAYL-FVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEknNVESVFAVNGFGFAG--RG 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 631 PNAAVMFTMLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGA 710
Cdd:PRK15127 622 QNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQ 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 711 VMGRAMQTPE-LAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRM 789
Cdd:PRK15127 702 LLGEAAKHPDmLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRM 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 790 QPEDIGRLKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASEtLPAGMAFEWT 869
Cdd:PRK15127 782 LPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASK-LPTGVGYDWT 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 870 DLAYQEKQAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAK 949
Cdd:PRK15127 861 GMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAK 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 950 NAILIVEFAR-AKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLL 1028
Cdd:PRK15127 941 NAILIVEFAKdLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIF 1020
|
1050 1060
....*....|....*....|....*.
gi 489595762 1029 LTPIFYVVVRRLAIRRSASPQQATEV 1054
Cdd:PRK15127 1021 FVPVFFVVVRRRFSRKNEDIEHSHTV 1046
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
5-1048 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 830.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 5 RFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQA 84
Cdd:PRK09577 3 RFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 85 ATdGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATLQV 164
Cdd:PRK09577 83 SA-GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 165 RDQLARLSGVGDVLVWGAgEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQ--PEaSAAFQVTVNTLGRL 242
Cdd:PRK09577 162 LQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSavPD-SAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 243 SSEQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEG 322
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 323 IEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVL 402
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 403 SIGIVVDDAIVVVENVERHIAL-GETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTIL 481
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEeGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 482 SAINSLTLSPALAGVLLKP----HHGdvKRDlltrvidfLFGWffrlFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGL 557
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPvdgdHHE--KRG--------FFGW----FNRFVARSTQRYATRVGAILKRPLRWLVVYGAL 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 558 VGMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNGmvNIPNAAVMF 637
Cdd:PRK09577 546 TAAAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYG--EGPNGGMIF 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 638 TMLKPFDERKDPSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAMQ 717
Cdd:PRK09577 624 VTLKDWKERKAARDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAK 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 718 TPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRL 797
Cdd:PRK09577 704 DPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKL 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 798 KVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASeTLPAGMAFEWTDLAYQEKQ 877
Cdd:PRK09577 784 RVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA-TLPAGIGYAWSGQSFEERL 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 878 AGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEF 957
Cdd:PRK09577 863 SGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEV 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 958 ARAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVV 1037
Cdd:PRK09577 943 AKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
1050
....*....|.
gi 489595762 1038 RRLaIRRSASP 1048
Cdd:PRK09577 1023 GRL-FDVGPRR 1032
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1039 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 742.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 5 RFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQA 84
Cdd:NF033617 2 DVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 85 ATdGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVqRIGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFATLQV 164
Cdd:NF033617 82 SL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEA-PDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 165 RDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQpeaSAAFQVTVNTlgRLSS 244
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGD---SVVSTVRAND--QLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 245 EQQFGEIVVKTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEGIE 324
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 325 YRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSI 404
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 405 GIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTILSAI 484
Cdd:NF033617 395 GLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGI 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 485 NSLTLSPALAGVLLKPHHGDVKrdlltrvidflfgwFFRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGMTWVG 564
Cdd:NF033617 475 VALTLTPMMCSRLLKANEKPGR--------------FARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 565 FQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLsvnGMVNIPNAAVMFTMLKPFD 644
Cdd:NF033617 541 YVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGV---GGNPGDNTGFGIINLKPWD 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 645 ERKDpslSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGlGSTGGFKIQIEDRAGLGFEALAQAQGAVMGRAMQTPELAGM 724
Cdd:NF033617 618 ERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADV 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 725 LASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLKVRNATG 804
Cdd:NF033617 694 DSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 805 NMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASETLPAGMAFEWTDLAYQEKQAGDTAMY 884
Cdd:NF033617 774 KLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLF 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 885 VFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA-RAKED 963
Cdd:NF033617 854 LFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFAnELQRH 933
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489595762 964 EGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVRR 1039
Cdd:NF033617 934 QGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1053 |
1.14e-163 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 509.38 E-value: 1.14e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 1 MNIPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 81 SSqAATDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQriGVVTQKTSPDILMVVHLVSPDNRYDPVYLSNFA 160
Cdd:PRK09579 81 TS-VSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAE--DPVLSKEAADASALMYISFYSEEMSNPQITDYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 161 TLQVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQpeasaaFQVT-VNTL 239
Cdd:PRK09579 158 SRVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGE------YVVTsINAS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 240 GRLSSEQQFGEIVVKTGTDGQVtRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGF 319
Cdd:PRK09579 232 TELKSAEAFAAIPVKTSGDSRV-LLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 320 PEGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFG 399
Cdd:PRK09579 311 PPNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 400 LVLSIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAIST 479
Cdd:PRK09579 391 MVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAV 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 480 ILSAINSLTLSPALAGVLLKPHHGDVkrdlltrvidflfGWFFRLfNRFFDGASTAYvWSVRRAARLSVLVLLVYAGLV- 558
Cdd:PRK09579 471 IISGIVALTLSPMMCALLLRHEENPS-------------GLAHRL-DRLFERLKQRY-QRALHGTLNTRPVVLVFAVIVl 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 559 GMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESvvafpGLSVNGMVNIPNAAVMFt 638
Cdd:PRK09579 536 ALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYS-----SFQINGFNGVQSGIGGF- 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 639 MLKPFDERkdpSLSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGStgGFKIQIEDRAGLGFEALAQAQGAVMGRAMQT 718
Cdd:PRK09579 610 LLKPWNER---ERTQMELLPLVQAKLEEIPGLQIFGFNLPSLPGTGE--GLPFQFVINTANDYESLLQVAQRVKQRAQES 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 719 PELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGRLK 798
Cdd:PRK09579 685 GKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYY 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 799 VRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPApgYSFGQATAAMERIASETLPAGMAFEWTDLAYQEKQA 878
Cdd:PRK09579 765 VKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNSAIISGFPI--VSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQE 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 879 GDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFA 958
Cdd:PRK09579 843 GSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFA 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 959 -RAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVV 1037
Cdd:PRK09579 923 nQLRHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
1050
....*....|....*.
gi 489595762 1038 rrlaIRRSASPQQATE 1053
Cdd:PRK09579 1003 ----AKPDAAPGVAQA 1014
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
2-1046 |
2.06e-141 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 451.02 E-value: 2.06e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 2 NIPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMS 81
Cdd:COG3696 4 RIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 82 SQAATdGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQriGVVTQKTSP--DILMVVhLVSPDNRYDPVYLSnf 159
Cdd:COG3696 84 SISRF-GLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVT--PELGPISTGlgEIYQYT-LESDPGKYSLMELR-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 160 aTLQ---VRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEasaafQVTV 236
Cdd:COG3696 158 -TLQdwvIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQ-----EYLV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 237 NTLGRLSSEQQFGEIVVKTgTDGQVTRLRDVARIELGAdsyALRS---LLNGK-PALAMQIIQSPGANALDVSSAVRTTM 312
Cdd:COG3696 232 RGIGLIRSLEDIENIVVKT-RNGTPVLLRDVAEVRIGP---APRRgaaTLNGEgEVVGGIVLMLKGENALEVIEAVKAKL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 313 AELQKGFPEGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSL 392
Cdd:COG3696 308 AELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISA 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 393 NTLSLFGLVLSIGIVVDDAIVVVENVERHiaLGETPKEAARKAMD--------EVTGPIVAITSVLSAVFIPSAFLSGLQ 464
Cdd:COG3696 388 NLMSLGGLAIDFGIIVDGAVVMVENILRR--LEENRAAGTPRERLevvleaarEVRRPIFFATLIIILVFLPIFTLEGVE 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 465 GEFYRQFALTIAISTILSAINSLTLSPALAGVLLKPHHGDVKrdlltrvidflfGWFFRLFNRffdgastAYVWSVRRAA 544
Cdd:COG3696 466 GKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKE------------NPLVRWLKR-------LYRPLLRWAL 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 545 RLSVLVLLVYAGLVGMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSV 624
Cdd:COG3696 527 RHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 625 NGM-VNIPNAAVMFTMLKPFDERKDPsLSAFAIAGKLMGKFSQIPdGFAGIFPPPpvpglgstggfkiqIEDR------- 696
Cdd:COG3696 607 DATdPMGVNMSETFVILKPRSEWRSG-RTKEELIAEMREALEQIP-GVNFNFSQP--------------IQMRvdellsg 670
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 697 --AGLG-------FEALAQAQGAVMGRAMQTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQV-----NL 762
Cdd:COG3696 671 vrADVAvkifgddLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETaiggkAV 750
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 763 GSLYANDfnrfgRTYRVMVQADAPFRMQPEDIGRLKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFP----SADISGS 838
Cdd:COG3696 751 GQVYEGE-----RRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRrivvQANVRGR 825
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 839 PAPGYsfgqATAAMERIASE-TLPAGMAFEWTDLAYQEKQAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMA 917
Cdd:COG3696 826 DLGSF----VAEAQAKVAEQvKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFA 901
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 918 LLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAILIVEFARAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPL 997
Cdd:COG3696 902 LIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPM 981
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*....
gi 489595762 998 VIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPIFYVVVRRLAIRRSA 1046
Cdd:COG3696 982 ALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAA 1030
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
5-1053 |
2.24e-123 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 402.96 E-value: 2.24e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 5 RFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAINGVENMLYMSSQA 84
Cdd:PRK10503 14 RLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 85 AtDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVqrigvvtqkTSPDILMVVHLVSPDNRYDPVYLSNFATLQV 164
Cdd:PRK10503 94 S-GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDL---------PNPPVYSKVNPADPPIMTLAVTSTAMPMTQV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 165 RD--------QLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVgQQPEASaafqVTV 236
Cdd:PRK10503 164 EDmvetrvaqKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSL-DGPTRA----VTL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 237 NTLGRLSSEQQFGEIVVkTGTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQ 316
Cdd:PRK10503 239 SANDQMQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 317 KGFPEGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLS 396
Cdd:PRK10503 318 ESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLT 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 397 LFGLVLSIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIA 476
Cdd:PRK10503 398 LMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 477 ISTILSAINSLTLSPALAGVLLKpHHGDVKRDLLTRVIDflfgwffrlfnRFFDGASTAYVWSVRRAARLSVLVLLVYAG 556
Cdd:PRK10503 478 VAILISAVVSLTLTPMMCARMLS-QESLRKQNRFSRASE-----------RMFDRVIAAYGRGLAKVLNHPWLTLSVALS 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 557 LVGMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGlsVNGMVNIPNAAVM 636
Cdd:PRK10503 546 TLLLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG--VDGTNPSLNSARL 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 637 FTMLKPFDERKDpslSAFAIAGKLMGKFSQIPDGFAGIFPPPPVPGLGSTGGFKIQIEDRAGlGFEALAQAQGAVMGRAM 716
Cdd:PRK10503 624 QINLKPLDERDD---RVQKVIARLQTAVAKVPGVDLYLQPTQDLTIDTQVSRTQYQFTLQAT-SLDALSTWVPKLMEKLQ 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 717 QTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRFGRTYRVMVQADAPFRMQPEDIGR 796
Cdd:PRK10503 700 QLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDT 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 797 LKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGMA--FEWTDLAY 873
Cdd:PRK10503 780 IRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTlNLPADITtqFQGSTLAF 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 874 QEkqAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGLAAKNAIL 953
Cdd:PRK10503 860 QS--ALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIM 937
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 954 IVEFARAKE-DEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPI 1032
Cdd:PRK10503 938 MIDFALAAErEQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPV 1017
|
1050 1060
....*....|....*....|.
gi 489595762 1033 FYVVVRRLAIRRSASPQQATE 1053
Cdd:PRK10503 1018 IYLLFDRLALYTKSRFPRHEE 1038
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
7-1053 |
1.23e-118 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 389.86 E-value: 1.23e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 7 FVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQA---INGVENMLYMSSQ 83
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSlgrIAGVNEMTSSSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 84 AATdgRMTLTIAFKQgtDPDMAQIQVQNRVSRALPRLPQEV-QRIGVVTQKTSPDILMVVHLVSpdNRYDPVYLSNFATL 162
Cdd:PRK10614 87 GST--RIILQFDFDR--DINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTS--DTYSQGQLYDFAST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 163 QVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVgqqPEASAAFQVTVNTlgRL 242
Cdd:PRK10614 161 QLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV---EDGTHRWQIQTND--EL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 243 SSEQQFGEIVVKTgTDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMAELQKGFPEG 322
Cdd:PRK10614 236 KTAAEYQPLIIHY-NNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 323 IEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVL 402
Cdd:PRK10614 315 IDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 403 SIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVAITSVLSAVFIPSAFLSGLQGEFYRQFALTIAISTILS 482
Cdd:PRK10614 395 ATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGIS 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 483 AINSLTLSPALAGVLLKPHHGDVKRDLltrvidflfgwffRLFNRFFDGASTAYVWSVRRAARLSVLVLLVYAGLVGMTW 562
Cdd:PRK10614 475 LLVSLTLTPMMCAWLLKSSKPREQKRL-------------RGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 563 VGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPGLSVNgmvnipNAAVMFTMLKP 642
Cdd:PRK10614 542 WLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRV------NSGMMFITLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 643 FDERKDpslSAFAIAGKLMGKFSQIPDgfAGIFPPP----PVPGLGSTGGFKIQI--EDraglgFEALAQAQGAVMGRAM 716
Cdd:PRK10614 616 LSERSE---TAQQVIDRLRVKLAKEPG--ANLFLMAvqdiRVGGRQSNASYQYTLlsDD-----LAALREWEPKIRKALA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 717 QTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVP-------LNTIFETLQVnlgSLYANDFNRfgrtYRVMVQADAPFRM 789
Cdd:PRK10614 686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDvqaanslLNNAFGQRQI---STIYQPLNQ----YKVVMEVDPRYTQ 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 790 QPEDIGRLKVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSPAPGYSFGQATAAMERIASE-TLPAGM--AF 866
Cdd:PRK10614 759 DISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQlGVPSTVrgSF 838
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 867 EWTDLAYQEKQagDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFVVLVGL 946
Cdd:PRK10614 839 AGTAQVFQETM--NSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGI 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 947 AAKNAILIVEFA-RAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAEMRHAMGIAVFAGMLGVTLF 1025
Cdd:PRK10614 917 VKKNAIMMVDFAlEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLL 996
|
1050 1060
....*....|....*....|....*...
gi 489595762 1026 GLLLTPIFYVVVRRLAIRRSASPQQATE 1053
Cdd:PRK10614 997 TLYTTPVVYLFFDRLRLRFSRKPKQTVT 1024
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
3-1051 |
8.69e-93 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 319.40 E-value: 8.69e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 3 IPRFFVDRPIFAVVLSVLMLIAGGLTLLKLPLSEYPQVTPPTVQVTASYPGANPAVIAETVAAPLEQAI---NGVENMLY 79
Cdd:TIGR00914 5 IISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMaglPGLETTRS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 80 MSSqaatDGRMTLTIAFKQGTDPDMAQIQVQNRVSRALPRLPQEVQ-RIGVVTQKTSPDILMVV-----HLVSPDNRYDP 153
Cdd:TIGR00914 85 LSR----YGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSpEMGPISTGLGEIFLYTVeaeegARKKDGGAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 154 VYLSNFATLQVRDQLARLSGVGDVLVWGAGEYSMRVWLDPAKVAARGLTASDVVGAIQEQNVQVAAGSVGQQPEasaafQ 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGE-----Q 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 234 VTVNTLGRLSSEQQFGEIVVKTGtDGQVTRLRDVARIELGADSYALRSLLNGKPALAMQIIQSPGANALDVSSAVRTTMA 313
Cdd:TIGR00914 236 YLVRAPGQVQSMDDIRNIVIATG-EGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 314 ELQKGFPEGIEYRIAYDPTVFVKASLEAVVMTLLEAVVLVVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLN 393
Cdd:TIGR00914 315 TINKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISAN 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 394 TLSLFGLvlSIGIVVDDAIVVVENVERHIA-----LGETPKEAAR-----KAMDEVTGPIVAITSVLSAVFIPSAFLSGL 463
Cdd:TIGR00914 395 LMSLGAL--DFGLIVDGAVVIVENAHRRLAeaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGV 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 464 QGEFYRQFALTIAISTILSAINSLTLSPALAGVLLKPHHGDVKrdlltrvidflfgwffrlfNRFFDGASTAYVWSVRRA 543
Cdd:TIGR00914 473 EGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKE-------------------NRLMRVLKRRYEPLLERV 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 544 ARLSVLVLLVYAGLVGMTWVGFQTVPGGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKKMSEIALAEPGVESVVAFPG-- 621
Cdd:TIGR00914 534 LAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGta 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 622 -LSVNGMVniPNAAVMFTMLKPFDERKDPSLSAFAIAGKLMGKFSQIPdGFAGIFPPPP-------VPGLGSTGGFKIQI 693
Cdd:TIGR00914 614 eIATDPMP--PNASDTYIILKPESQWPEGKKTKEDLIEEIQEATVRIP-GNNYEFTQPIqmrfnelISGVRSDVAVKVFG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 694 EDRAGLgfEALAQAQGAVmgrAMQTPELAGMLASFQVNAPQVQVDIDRVKAKSQGVPLNTIFETLQVNLGSLYANDFNRF 773
Cdd:TIGR00914 691 DDLDDL--DATAEKISAV---LKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEG 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 774 GRTYRVMVQADAPFRMQPEDIGRL-----KVRNATGNMIPLSALLTIKHSSGPDRVMHYNGFPSADISGSpAPGYSFGQ- 847
Cdd:TIGR00914 766 DRRFDIVIRLPESLRESPQALRQLpiplpLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSAN-VRGRDLGSf 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 848 ATAAMERIASET-LPAGMAFEWTDLAYQEKQAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVW 926
Cdd:TIGR00914 845 VDDAKKAIAEQVkLPPGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALW 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 927 FTGGDNNIFTQIGFVVLVGLAAKNAILIVEFARAKEDEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIATGAGAE 1006
Cdd:TIGR00914 925 LRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAE 1004
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*..
gi 489595762 1007 MRHAMGIAVFAGMLGVTLFGLLLTPIFYVVV--RRLAIRRSASPQQA 1051
Cdd:TIGR00914 1005 VQRPLATVVIGGIITATLLTLFVLPALYRLVhrRRHKGRKEHEPLEG 1051
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
363-1045 |
1.61e-11 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 68.35 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 363 TWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLS--LFGLVLSIGivvddaivvvenV----------ERHIALGETPKE 430
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG------------IdygihllnryREERRKGLDKRE 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 431 AARKAMDEVTGPIVaITSVLSAVfipsAFLSGLQGEF--YRQFALTIAISTILSAINSLTLSPALAgVLLKPHHGDVKRD 508
Cdd:COG1033 309 ALREALRKLGPPVL-LTSLTTAI----GFLSLLFSDIppIRDFGIVAAIGVLLAFLTSLTLLPALL-SLLPRPKPKTRRL 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 509 LLTRVIDFLFGWFFRLFNRffdgastayvwsvRRAARLSVLVLLVYAGLVGMTWVGFQTVPGGFVPAQDKYYLvgiaqlp 588
Cdd:COG1033 383 KKPPELGRLLAKLARFVLR-------------RPKVILVVALVLAVVSLYGISRLKVEYDFEDYLPEDSPIRQ------- 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 589 tgasldrteaVVKKMSEIalaepgvesvvafpglsvngmvnipnaavmftmlkpfderkdpslsafaiagklmgkfsqip 668
Cdd:COG1033 443 ----------DLDFIEEN-------------------------------------------------------------- 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 669 dgfagifppppvpgLGSTGGFKIQIEDRAGLGfealaqaqgavmgramqtpelagmlasfqVNAPQVQVDIDRVKAKSQG 748
Cdd:COG1033 451 --------------FGGSDPLEVVVDTGEPDG-----------------------------LKDPEVLKEIDRLQDYLES 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 749 VPL----NTIFETLQVNLGSLYANDFNRFG--RTYRVMVQADAPFRMQPEDIGRlKVRNATGNMIPLSALLtikhssgpd 822
Cdd:COG1033 488 LPEvgkvLSLADLVKELNQALNEGDPKYYAlpESRELLAQLLLLLSSPPGDDLS-RFVDEDYSAARVTVRL--------- 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 823 rvmhyngfpsADISGSpapgYSFGQATAAMERIASETLPAGMAFEWTDLAYQEKQAGDT----AMYVFPLSVLLAFLILA 898
Cdd:COG1033 558 ----------KDLDSE----EIKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINESviesQIRSLLLALLLIFLLLL 623
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 899 AQYNSWSLpfAVLLIAPMAL-LSAIAGVW-FTGGDNNIFTQIGFVVLVGLAAKNAILIVEFARAKEDEGVDPLAAVLEAA 976
Cdd:COG1033 624 LAFRSLRL--GLISLIPNLLpILLTFGLMgLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRAL 701
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 977 RLRLRPILMTSLAFIAGVIPLVIATGAG-AEMRHAMGIAVFAGMLGVtlfgLLLTPIFYVVVRRLAIRRS 1045
Cdd:COG1033 702 RTTGKAILFTSLTLAAGFGVLLFSSFPPlADFGLLLALGLLVALLAA----LLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
862-1045 |
6.12e-11 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 66.81 E-value: 6.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 862 AGMAFEWTDLAyqeKQAGDTAMYVFPLSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAIAGVWFTGGDNNIFTQIGFV 941
Cdd:COG1033 203 TGFPVLRGDIA---EAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPP 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 942 VLVGLAAKNAI-LIVEFARAKEdEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIPLVIatgAGAEMRHAMGIAVFAGML 1020
Cdd:COG1033 280 LLLAIGIDYGIhLLNRYREERR-KGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAIGVL 355
|
170 180
....*....|....*....|....*
gi 489595762 1021 GVTLFGLLLTPIFYVVVRRLAIRRS 1045
Cdd:COG1033 356 LAFLTSLTLLPALLSLLPRPKPKTR 380
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
280-494 |
9.32e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 52.92 E-value: 9.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 280 RSLLNGKPALAMQIIQSPGAN----ALDVSSAVRTTMAELQkgFPEGIEYRIAYDPTV---FVKASLEAVVMTLLEAVVL 352
Cdd:TIGR00921 128 EMFLSKDHTVAIIIVQLKSDAdykqVVPIYNDVERSLERTN--PPSGKFLDVTGSPAInydIEREFGKDMGTTMAISGIL 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 353 VVIVVVLFLQTWRASIIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHIALGETPKEAA 432
Cdd:TIGR00921 206 VVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAI 285
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489595762 433 RKAMDEvTGPIVAITSVLSAVFIPSAFLSGLQgeFYRQFALTIAISTILSAINSLTLSPALA 494
Cdd:TIGR00921 286 VTAVRR-TGRAVLIALLTTSAGFAALALSEFP--MVSEFGLGLVAGLITAYLLTLLVLPALL 344
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
847-1031 |
2.72e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 48.22 E-value: 2.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 847 QATAAMERIASETLPAGMAFEWTDLAYQEKQAGDTAMYVFP----LSVLLAFLILAAQYNSWSLPFAVLLIAPMALLSAI 922
Cdd:COG2409 132 EAVDALRDAVAAAPAPGLTVYVTGPAALAADLNEAFEEDLGraelITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVAL 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 923 AGVWFTGG--DNNIFTQiGFVVLVGLAAKN--AILIVefARAKE--DEGVDPLAAVLEAARLRLRPILMTSLAFIAGVIP 996
Cdd:COG2409 212 GLLALLAAftDVSSFAP-NLLTMLGLGVGIdyALFLV--SRYREelRAGEDREEAVARAVATAGRAVLFSGLTVAIALLG 288
|
170 180 190
....*....|....*....|....*....|....*
gi 489595762 997 LVIatgAGAEMRHAMGIAVFAGMLGVTLFGLLLTP 1031
Cdd:COG2409 289 LLL---AGLPFLRSMGPAAAIGVAVAVLAALTLLP 320
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
368-493 |
3.85e-05 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 47.28 E-value: 3.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 368 IIPLVAVPVSLVGTFALMYMFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHIALGETPKEAARKAMDEVTGPIVA-- 445
Cdd:TIGR01129 274 LIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDan 353
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 489595762 446 ITSVLSAVFIpSAFLSG-LQGefyrqFALTIAISTILSAINSLTLSPAL 493
Cdd:TIGR01129 354 ITTLIAALIL-YVFGTGpVKG-----FAVTLAIGIIASLFTALVFTRLL 396
|
|
| 2A060602 |
TIGR00918 |
The Eukaryotic (Putative) Sterol Transporter (EST) Family; |
364-493 |
3.96e-04 |
|
The Eukaryotic (Putative) Sterol Transporter (EST) Family;
Pssm-ID: 273338 [Multi-domain] Cd Length: 1145 Bit Score: 44.49 E-value: 3.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489595762 364 WRASIIPLVaVPVSLVGTFALMYMFGFSLNTLSLFGLVLSIGIVVDDaivvveNVerHIALGETPKEAARK-----AMDE 438
Cdd:TIGR00918 990 WTAGLIVLV-LALMTVELFGMMGLLGIKLSAIPVVILIASVGIGVEF------TV--HIALGFLTAIGDRNrravlALEH 1060
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 489595762 439 VTGPIV--AITSVLsAVFIpsafLSGLQGEF-YRQFALTIAISTILSAINSLTLSPAL 493
Cdd:TIGR00918 1061 MFAPVLdgALSTLL-GVLM----LAGSEFDFiVRYFFAVLAVLTCLGVLNGLVLLPVL 1113
|
|
| |
