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Conserved domains on  [gi|489626468|ref|WP_003530908|]
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MULTISPECIES: ABC transporter permease [Sinorhizobium]

Protein Classification

ABC transporter permease( domain architecture ID 11467922)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter, which may be involved in the transport of one or more from a variety of substrates such as nopaline and octopine

Gene Ontology:  GO:0140359|GO:0042626|GO:0043190|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 45-270 8.94e-89

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 263.11  E-value: 8.94e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  45 MRWDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPlllqlwllyyglgsL- 123
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTP--------------Ll 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 124 ---------FPQFPAIRQSFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLP 194
Cdd:COG4160   67 vqlfliyygLGQFEWVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILP 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489626468 195 RAIHRALPTLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRIP 270
Cdd:COG4160  147 SALRRALPAYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLL 222
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 45-270 8.94e-89

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 263.11  E-value: 8.94e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  45 MRWDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPlllqlwllyyglgsL- 123
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTP--------------Ll 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 124 ---------FPQFPAIRQSFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLP 194
Cdd:COG4160   67 vqlfliyygLGQFEWVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILP 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489626468 195 RAIHRALPTLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRIP 270
Cdd:COG4160  147 SALRRALPAYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLL 222
PRK15069 PRK15069
histidine ABC transporter permease HisM;
59-268 1.89e-37

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 132.10  E-value: 1.89e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  59 SGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGSLfpqfPAIR-QSFLWP 137
Cdd:PRK15069  21 TGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSL----EIVRgTDLLDA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 138 YLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPL 217
Cdd:PRK15069  97 FFRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489626468 218 VATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENR 268
Cdd:PRK15069 177 AFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERR 227
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 47-269 5.47e-18

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 80.28  E-value: 5.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468   47 WDWLPRYLPRLGSGILVSLAmlfsTAILGFLLAVPLGLA----QVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYglgs 122
Cdd:TIGR03003   3 WEFVRQILPTLIEGLKITIL----ATALGFAIAAVLGLVfailRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYY---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  123 LFPQFPAIRQSFLwpylreawpYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALP 202
Cdd:TIGR03003  75 VLPDIGIRLPALV---------AGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIP 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489626468  203 TLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:TIGR03003 146 ALGNYLVAMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-260 1.79e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 64.22  E-value: 1.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  61 ILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLqlwllyyglgSLFPQFPAIRQSFLWPYLR 140
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLV----------LGLLLVLLFGVLLGWGILP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 141 EAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPLVAT 220
Cdd:cd06261   71 GLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 489626468 221 ITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVV 260
Cdd:cd06261  151 LGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 124-269 5.06e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 5.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  124 FPQFPAIRQSFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPT 203
Cdd:pfam00528  33 FVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTG 112

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489626468  204 LNGETVLQLKSTPLVATIT---VVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:pfam00528 113 LALAFGGALGGAVLLEFLGswpGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 45-270 8.94e-89

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 263.11  E-value: 8.94e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  45 MRWDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPlllqlwllyyglgsL- 123
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTP--------------Ll 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 124 ---------FPQFPAIRQSFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLP 194
Cdd:COG4160   67 vqlfliyygLGQFEWVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILP 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489626468 195 RAIHRALPTLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRIP 270
Cdd:COG4160  147 SALRRALPAYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLL 222
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 44-269 7.33e-47

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 156.00  E-value: 7.33e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  44 FMRWDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLllqlwllyyglgsl 123
Cdd:COG0765    2 FFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPL-------------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 124 fpqfpaIRQSFLW----PYLR---EAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRA 196
Cdd:COG0765   68 ------LVQLFFIyfglPLLGidlSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQA 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489626468 197 IHRALPTLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:COG0765  142 LRIILPPLGNEFISLLKDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
PRK15069 PRK15069
histidine ABC transporter permease HisM;
59-268 1.89e-37

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 132.10  E-value: 1.89e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  59 SGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGSLfpqfPAIR-QSFLWP 137
Cdd:PRK15069  21 TGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSL----EIVRgTDLLDA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 138 YLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPL 217
Cdd:PRK15069  97 FFRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489626468 218 VATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENR 268
Cdd:PRK15069 177 AFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERR 227
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
53-268 1.85e-30

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 114.07  E-value: 1.85e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  53 YLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGSLFPQfpaIRQ 132
Cdd:COG4215   14 WGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQILLNA---LAD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 133 SFLWPYLREAWPY--GVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVL 210
Cdd:COG4215   91 LFGYDGFIEINPFvaGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALPGLGNNWLV 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489626468 211 QLKSTPLVATITVVDVyaviskVRQETYL---TYEPL---LLLAAIYMCLTAILVVAFRYFENR 268
Cdd:COG4215  171 LLKDTALVSVIGLVDL------VRQAQEAagsTREPFtfyLAAALIYLALTTVSELVLARLERR 228
artM PRK11122
arginine ABC transporter permease ArtM;
53-269 2.82e-29

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 110.43  E-value: 2.82e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  53 YLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGslfpQFPAIRQ 132
Cdd:PRK11122   4 YLPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPG----QFPWLQE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 133 -SFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRW-TMfrRIWLPRAIHRALPTLNGETVL 210
Cdd:PRK11122  80 yPWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKqTL--RILLPYAFKRALSSYSNEVVL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489626468 211 QLKSTPLVATITVVDV--YAviskvRQETYLTYEPLLLLAA--IYMCLTAILVVAFRYFENRI 269
Cdd:PRK11122 158 VFKSTSLAYTITLMDVmgYS-----QLLYGRTYDVMVFGAAgiIYLVVNGLLTLLMRLIERKA 215
PRK15100 PRK15100
cystine ABC transporter permease;
48-269 5.12e-19

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 82.87  E-value: 5.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  48 DWLPRYLPRLGSGILVSLAMLFSTAILGFLLAvplgLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGSLFPQF 127
Cdd:PRK15100  10 DSAPFLLKGAGYTLQLSIGGMFFGLLLGFILA----LMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQFGIEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 128 PAIrqsflwpylreawPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGE 207
Cdd:PRK15100  86 DPI-------------PAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNS 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489626468 208 TVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:PRK15100 153 FISLVKDTSLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQL 214
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 45-269 3.65e-18

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 80.87  E-value: 3.65e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  45 MRWDW--LPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLwllyyglgs 122
Cdd:PRK09494   1 MQFDWsaIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQV--------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 123 LFPQFPAirqSFLWPYLR-EAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRAL 201
Cdd:PRK09494  72 MFIYFAL---PMAFNDLRiDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRML 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489626468 202 PTLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:PRK09494 149 PPLGNQWIISIKDTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERRM 216
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 47-269 5.47e-18

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 80.28  E-value: 5.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468   47 WDWLPRYLPRLGSGILVSLAmlfsTAILGFLLAVPLGLA----QVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYglgs 122
Cdd:TIGR03003   3 WEFVRQILPTLIEGLKITIL----ATALGFAIAAVLGLVfailRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYY---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  123 LFPQFPAIRQSFLwpylreawpYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALP 202
Cdd:TIGR03003  75 VLPDIGIRLPALV---------AGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIP 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489626468  203 TLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:TIGR03003 146 ALGNYLVAMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
146-268 3.45e-15

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 72.79  E-value: 3.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 146 GVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPLVATITVVD 225
Cdd:PRK11123 107 GVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVND 186

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 489626468 226 VY---AVISKVRQETYLTYeplLLLAAIYMCLTAILVVAFRYFENR 268
Cdd:PRK11123 187 LMlqtKSIATRTQEPFTWY---IIAAAIYLVITLISQYILKRIELR 229
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-260 1.79e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 64.22  E-value: 1.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  61 ILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLqlwllyyglgSLFPQFPAIRQSFLWPYLR 140
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLV----------LGLLLVLLFGVLLGWGILP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 141 EAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPLVAT 220
Cdd:cd06261   71 GLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 489626468 221 ITVVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVV 260
Cdd:cd06261  151 LGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
146-257 9.16e-11

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 60.19  E-value: 9.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 146 GVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPTLNGETVLQLKSTPLVATITVVD 225
Cdd:PRK15135  96 GIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLGLED 175

                         90       100       110
                 ....*....|....*....|....*....|..
gi 489626468 226 VYAVISKVRQETYLTYEPLLLLAAIYMCLTAI 257
Cdd:PRK15135 176 VVKATQLAGKSTWEPFYFAIVCGVIYLVFTTV 207
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 53-164 1.34e-05

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 42.90  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468   53 YLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFCTVIRGTPLLLQLWLLYYGLGSLFPQFPairq 132
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLIGIRLS---- 76

                          90       100       110
                  ....*....|....*....|....*....|..
gi 489626468  133 sflwpylreAWPYGVAALTVSFAAYEGEVMRG 164
Cdd:TIGR01726  77 ---------PLTAAVIALTLFYGAYLAEIFRG 99
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
47-262 1.96e-05

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 44.82  E-value: 1.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  47 WDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTG----PWFfkapARIFCTVIRGTPLLLQLWLLYYGLGS 122
Cdd:PRK15107   6 WSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSfkpvAWF----AKAYVNVFRSIPLVMVLLWFYLIVPG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468 123 LFPQFPAIRqsflwPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALP 202
Cdd:PRK15107  82 FLQNVLGLS-----PKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVP 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489626468 203 TLNGETVLQLKSTPLVATITVVDVYAVISKVRQETYLTYEPLLLLAAIY--MCLTAILVVAF 262
Cdd:PRK15107 157 LLLTQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYfvISLSASLLVSY 218
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 124-269 5.06e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 5.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  124 FPQFPAIRQSFLWPYLREAWPYGVAALTVSFAAYEGEVMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRAIHRALPT 203
Cdd:pfam00528  33 FVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTG 112

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489626468  204 LNGETVLQLKSTPLVATIT---VVDVYAVISKVRQETYLTYEPLLLLAAIYMCLTAILVVAFRYFENRI 269
Cdd:pfam00528 113 LALAFGGALGGAVLLEFLGswpGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 44-108 2.10e-04

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 41.60  E-value: 2.10e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489626468  44 FMRWDWlpRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGL--AQVTGPW-FFKAPARIFCTVIRGTP 108
Cdd:COG3639   38 FFPPDW--SYLPDLLSALLETLAIALLGTLLGAVLALPLAFlaARNLAPNpWVRLLARRLLNVLRAIP 103
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 55-196 2.15e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.59  E-value: 2.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  55 PRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFFKAPARIFcTVIRGTPLLlqlwllyyglgSLFPQFpairqsF 134
Cdd:COG0600   57 GELWEHLLASLLRVLLGFALAALLGVPLGLLLGLSRLLRRLLDPLL-VFLRPIPPL-----------ALAPLL------I 118

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489626468 135 LWPYLREAWPYGVAALTVSFAAYEGevMRGAFAGVPSGELEAARAYGMGRWTMFRRIWLPRA 196
Cdd:COG0600  119 LWFGIGEASKIFVIFLGAFFPILLN--TAAGVRSVDPELLELARSLGASRWQILRKVVLPAA 178
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 44-108 4.40e-03

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 37.52  E-value: 4.40e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489626468   44 FMRWDWLprYLPRLGSGILVSLAMLFSTAILGFLLAVPLGL--AQVTGP-WFFKAPARIFCTVIRGTP 108
Cdd:TIGR01097  45 MFPPDWS--YLPRILKALLETLAMAILGTVLAAVLAVPLALlaARNITPsPWLYGLARLLLNFLRAIP 110
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 47-197 4.55e-03

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 37.34  E-value: 4.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489626468  47 WDWLPRYLPRLGSGILVSLAMLFSTAILGFLLAVPLGLAQVTGPWFfKAPARIFCTVIRGTPLLlqlwllyyglgSLFpq 126
Cdd:COG1174    6 IEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRL-AGLVLGVANILQTIPSL-----------ALL-- 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489626468 127 fpairqSFLWPYLREAWPYGVAALTV-SFAAyegeVMRGAFAG---VPSGELEAARAYGMGRWTMFRRIWLPRAI 197
Cdd:COG1174   72 ------ALLIPLLGIGPAPAIIALVLyALLP----ILRNTYTGlrsVDPAVVEAARGMGMTPWQRLWRVELPLAL 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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