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Conserved domains on  [gi|489628046|ref|WP_003532486|]
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MULTISPECIES: carbohydrate ABC transporter permease [Sinorhizobium]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 19-294 1.62e-105

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 308.56  E-value: 1.62e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  19 RRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDEIFAST-SLWPSSVDFSSYVRGWFglDVSFGRFFWNSLVIAVL 97
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAVV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  98 TVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQ 177
Cdd:COG0395   86 STVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQ 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 178 FFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLRTFVDSSSTs 257
Cdd:COG0395  166 FFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGT- 244

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489628046 258 DWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  245 DWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 19-294 1.62e-105

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 308.56  E-value: 1.62e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  19 RRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDEIFAST-SLWPSSVDFSSYVRGWFglDVSFGRFFWNSLVIAVL 97
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAVV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  98 TVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQ 177
Cdd:COG0395   86 STVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQ 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 178 FFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLRTFVDSSSTs 257
Cdd:COG0395  166 FFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGT- 244

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489628046 258 DWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  245 DWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
malG PRK10998
maltose ABC transporter permease MalG;
26-294 4.39e-33

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 122.90  E-value: 4.39e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  26 FLVHAALIAASIAMIYPLLWMISASVRPEDeiFASTSLWPSSVDFSSYvRGWFGLDVSFG------------RFFWNSLV 93
Cdd:PRK10998  14 FATHLLLLGFIALIMFPLLMVIAISLREGN--FATGSLIPEQISWEHW-KLALGFSVEHAdgrvtpppfpvlLWLWNSVK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  94 IAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPL-----VVPKFLASD 168
Cdd:PRK10998  91 VAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLnthggVIFAYLGGI 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 169 AFFIFLMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLR 248
Cdd:PRK10998 171 ALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQ 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489628046 249 TFVDSSSTSdWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:PRK10998 251 QYLNPQNYL-WGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-273 8.57e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.55  E-value: 8.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  88 FWNSLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLAS 167
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 168 DAFFIFLMVQFFRG----IPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNdMNSYTI 243
Cdd:cd06261   81 LLLIAPFARLIRRAalesIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG-GEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 489628046 244 QLGLRTFVDSSSTSDWGGLFAMSTLSLVPV 273
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-271 7.99e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 7.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  108 LAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQFFRGIPRELD 187
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  188 EAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLND--MNSYTIQLGLRTFVDSSSTSDWGGLFAM 265
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpgLGLLLIEAILGYDYPEIQGPVLAAALIL 163


                  ....*.
gi 489628046  266 STLSLV 271
Cdd:pfam00528 164 LLLNLL 169
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 26-233 5.88e-06

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 47.37  E-value: 5.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046   26 FLVHAALIAA-SIAMIYPLLWMISASVRPEDEIFASTSlwpssvDFSSYVRgwfglDVSFGRFFWNSLVIAVLTVVGNVV 104
Cdd:TIGR03262   4 RLLLAGMILAlLLFLLLPLLALLTKSVYDSDGDFIGLA------NFAEYFA-----TPGLLQSLGNSLTVSAIVTAIVVP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  105 ACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLV----VPKFLASDAFFIF-----LM 175
Cdd:TIGR03262  73 LAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFsiygFWGIVIGEVFYTFphalmIL 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489628046  176 VQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLI 233
Cdd:TIGR03262 153 VTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 19-294 1.62e-105

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 308.56  E-value: 1.62e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  19 RRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDEIFAST-SLWPSSVDFSSYVRGWFglDVSFGRFFWNSLVIAVL 97
Cdd:COG0395    8 RRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAVV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  98 TVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQ 177
Cdd:COG0395   86 STVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQ 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 178 FFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLRTFVDSSSTs 257
Cdd:COG0395  166 FFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGT- 244

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489628046 258 DWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  245 DWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 17-294 1.57e-66

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 209.24  E-value: 1.57e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  17 TGRRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDEIFaSTSLWPSSVDFSSYVRGWFGLDvsFGRFFWNSLVIAV 96
Cdd:COG3833    7 RKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLY-SSSLIPENFTLENYKKLFTETP--FLRWFLNSLIVAV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  97 LTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMV 176
Cdd:COG3833   84 VTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMK 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 177 QFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLRTFVDSSST 256
Cdd:COG3833  164 GYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRN 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489628046 257 SDWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG3833  244 TNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVK 281
malG PRK10998
maltose ABC transporter permease MalG;
26-294 4.39e-33

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 122.90  E-value: 4.39e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  26 FLVHAALIAASIAMIYPLLWMISASVRPEDeiFASTSLWPSSVDFSSYvRGWFGLDVSFG------------RFFWNSLV 93
Cdd:PRK10998  14 FATHLLLLGFIALIMFPLLMVIAISLREGN--FATGSLIPEQISWEHW-KLALGFSVEHAdgrvtpppfpvlLWLWNSVK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  94 IAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPL-----VVPKFLASD 168
Cdd:PRK10998  91 VAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLnthggVIFAYLGGI 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 169 AFFIFLMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLR 248
Cdd:PRK10998 171 ALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQ 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489628046 249 TFVDSSSTSdWGGLFAMSTLSLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:PRK10998 251 QYLNPQNYL-WGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
29-288 1.20e-30

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 115.99  E-value: 1.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  29 HAALIAASIAMIYPLLWMISASVRPEDEIFA-------STSLWPSSVDFssYVRGWFGLDVSFGRFFWNSLVIAVLTVVG 101
Cdd:PRK10973  13 HTMLILGIAVILFPLYVAFVAATLDKQAVFAvpmtlipGTHLLENIANI--WVNGVGNNSAPFGRMLLNSFVMAFSITVG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 102 NVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPkfLASDAFFIFLMVQFFRG 181
Cdd:PRK10973  91 KITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLP--LMASATATFLFRQFFMT 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 182 IPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNDMNSYTIQLGLRTFVDSS-STSDWG 260
Cdd:PRK10973 169 LPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGeGTTEWN 248

                        250       260
                 ....*....|....*....|....*...
gi 489628046 261 GLFAMSTLSLVPVFFFFLFFQRLLIEGI 288
Cdd:PRK10973 249 QVMAAMLLTLIPPVVIVLAMQRAFVRGL 276
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 20-228 6.78e-25

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 100.19  E-value: 6.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  20 RGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDeifaSTSLWPSSVDFSSYVRGWfgLDVSFGRFFWNSLVIAVLTV 99
Cdd:COG1177    1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSW----FLTFPPEGFTLRWYAELF--SDPRLLDALLNSLLIALLST 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 100 VGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQFF 179
Cdd:COG1177   75 LLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLARL 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 489628046 180 RGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDF 228
Cdd:COG1177  155 QGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEF 203
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
6-228 6.52e-17

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 79.02  E-value: 6.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046   6 MSSVTAPPPVPTGRRGPVGSFLVHA-ALIAASIAMIYPLLWMISASVRPEDEIfastSLWPSSVDFSSYVRgWFGlDVSF 84
Cdd:COG1175    1 MTTTTSAAARRRRRRRRLAAYLFLLpALLLLLVFVLYPLLYTLYLSFTDWNLL----GPPPEFVGLDNYAR-LFT-DPRF 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  85 GRFFWNSLVIAVLTVVGNVVACSLAAYAFARlRFAGRNFWFAIMLGTMMIPYHVT-LIPQYVLFLDLGWVNTFLPLV--- 160
Cdd:COG1175   75 WNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVaLIWKWLFNPDYGLLNALLGALgle 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 161 VPKFLASDAFFIFLMV-----QFF-----------RGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWT 224
Cdd:COG1175  154 PINWLGDPSLALPAVIivtvwKGTgfnmliflaglQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGA 233


                 ....
gi 489628046 225 WDDF 228
Cdd:COG1175  234 LQVF 237
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-273 8.57e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.55  E-value: 8.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  88 FWNSLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLAS 167
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 168 DAFFIFLMVQFFRG----IPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLNdMNSYTI 243
Cdd:cd06261   81 LLLIAPFARLIRRAalesIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG-GEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 489628046 244 QLGLRTFVDSSSTSDWGGLFAMSTLSLVPV 273
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 19-224 1.21e-16

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 78.27  E-value: 1.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  19 RRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPEDEIFASTSLWpssvDFSSYVRgwFGLDVSFGRFFWNSLVIAVLT 98
Cdd:COG1176    6 RRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF----TLENYAR--LFTDPLYLKVLLRTLWIALLT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  99 VVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFL--------PLvvpKFLASDAF 170
Cdd:COG1176   80 TLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLlalglidePL---RLLYTEFA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489628046 171 FIFLMVQFF------------RGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWT 224
Cdd:COG1176  157 VVIGLVYVYlpfmvlplyaalEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPA 222
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
17-233 3.99e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 75.20  E-value: 3.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  17 TGRRGPVGSFLVHAALIAAsiAMIYPLLWMISASVRPEDEIFASTslwpssvdFSSYVrgwfgldvsFGRFFWNSLVIAV 96
Cdd:COG1178    4 RPRRRPRLLLLLLALLLAL--LVLLPLLALLLRAFTDGLANFWAL--------LSDPY---------LWRALGNTLLLAL 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  97 LTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLAS--------- 167
Cdd:COG1178   65 LVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPPDiyglggiil 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489628046 168 -DAFFIF-----LMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLI 233
Cdd:COG1178  145 vLVLFNYpyvylLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLV 216
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-271 7.99e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 7.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  108 LAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASDAFFIFLMVQFFRGIPRELD 187
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  188 EAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLIYLND--MNSYTIQLGLRTFVDSSSTSDWGGLFAM 265
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpgLGLLLIEAILGYDYPEIQGPVLAAALIL 163


                  ....*.
gi 489628046  266 STLSLV 271
Cdd:pfam00528 164 LLLNLL 169
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-222 8.26e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.18  E-value: 8.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  12 PPPVPTGRRGPVGSFLVHAALIAASIAMIYPLLWMISASVRPedeifastsLWPSSVDFSSYVRGWFglDVSFGRFFWNS 91
Cdd:COG1178  275 ARRPRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTK---------ALDDNLTLDNYRFVLL--DPSLLRALLNS 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  92 LVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIP---YHVTLIPQYVLFLDLGWVNTFLPLVVPKFLASD 168
Cdd:COG1178  344 LLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPgivLGLGLLLLFNRPLPLLLYGTLAILVLAYVVRFL 423

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489628046 169 AFFIFLMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFI 222
Cdd:COG1178  424 PFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFV 477
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 88-221 8.28e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 58.22  E-value: 8.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  88 FWNSLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLAS 167
Cdd:COG0555   56 LKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIKVAFT 135

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489628046 168 DA------FFIFL-----MVQ-FFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSF 221
Cdd:COG0555  136 PLgivlaqTFVSLpfvvrTVQpVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF 201
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 88-227 5.01e-09

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 55.76  E-value: 5.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  88 FWNSLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLVVPKFLAS 167
Cdd:PRK09500  59 AQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAHITFC 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046 168 DAFFIFLMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDD 227
Cdd:PRK09500 139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDD 198
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 26-233 5.88e-06

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 47.37  E-value: 5.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046   26 FLVHAALIAA-SIAMIYPLLWMISASVRPEDEIFASTSlwpssvDFSSYVRgwfglDVSFGRFFWNSLVIAVLTVVGNVV 104
Cdd:TIGR03262   4 RLLLAGMILAlLLFLLLPLLALLTKSVYDSDGDFIGLA------NFAEYFA-----TPGLLQSLGNSLTVSAIVTAIVVP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  105 ACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGWVNTFLPLV----VPKFLASDAFFIF-----LM 175
Cdd:TIGR03262  73 LAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFsiygFWGIVIGEVFYTFphalmIL 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489628046  176 VQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTWDDFFGPLI 233
Cdd:TIGR03262 153 VTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
cysT CHL00187
sulfate transport protein; Provisional
 91-221 8.49e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 43.08  E-value: 8.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  91 SLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTLIPQYVLFLDLGW------------VNTFLP 158
Cdd:CHL00187  60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWighllshlgiqiVFTKLG 139

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489628046 159 LVVPKFLASDAFFIFLMVQFFRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSF 221
Cdd:CHL00187 140 VLLAMIFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTF 202
modB PRK09421
molybdate ABC transporter permease subunit;
91-221 6.95e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 40.29  E-value: 6.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  91 SLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPYHVTlipQYVLFLDLG-------WVNTFLPLVVP- 162
Cdd:PRK09421  14 SLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVT---GYLLLISMGrrgfigqWLYEWFGISFAf 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489628046 163 ----KFLASDAFFIFLMVQFFR----GIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSF 221
Cdd:PRK09421  91 swrgAALAAAVMAFPLMVRAIRlsleAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 18-217 2.83e-03

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 39.08  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  18 GRRGPVGSFLVHAALIAASIAMIYP-------LLWMISASVRPEDeifastsLWPSSVDFSSYVRGWFGLdvsfGRFFWN 90
Cdd:COG4135  292 GRRGLGDPALRRLGLALMLLIALLSllglallLLWSFAGRWRFPD-------ALPSSWTLRFWQRAAPGL----LEPLGN 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  91 SLVIAVLTVVGNVVACSLAAYAFARLRFAGRNFWFAIMLGTMMIPyHVTLIP-QYVLFLDLGWVNTFLPLVvpkflASDA 169
Cdd:COG4135  361 TLLLALASALIALVLVLACLEAEARRGRRPGRRALWLLYLPLLVP-QIAFLFgLQVLLLRLGLDGTWLAVI-----WAHL 434

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489628046 170 FFIFLMVQF-----FRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAA 217
Cdd:COG4135  435 VFVLPYVFLslagpWRALDPRYAQVAASLGASPWRVFWRVKLPLLLRPILTAA 487
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 78-225 3.42e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.21  E-value: 3.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628046  78 FGLDVSFGRFFWNSLVIAVLTVVGNVVACSLA---AYAFARLRFAgRNFWFAIMLGTMMIPyHVTLIPQYVLFLDLGWvn 154
Cdd:COG0600   50 LVELLASGELWEHLLASLLRVLLGFALAALLGvplGLLLGLSRLL-RRLLDPLLVFLRPIP-PLALAPLLILWFGIGE-- 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489628046 155 tfLPLVVPKFLASdAFFIFLMVQF-FRGIPRELDEAAMMDGCGAWRIYWKIMLPLSLPVLATAAIFSFIWTW 225
Cdd:COG0600  126 --ASKIFVIFLGA-FFPILLNTAAgVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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