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Conserved domains on  [gi|489628083|ref|WP_003532523|]
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MULTISPECIES: APC family permease [Sinorhizobium]

Protein Classification

APC family permease( domain architecture ID 11425014)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857|GO:0015171|GO:0006865
PubMed:  23177982|24038584|25043943|10931886
SCOP:  4006243
TCDB:  2.A.3.1|2.A.3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
15-447 2.14e-55

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


:

Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 190.49  E-value: 2.14e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  15 RLLRVLGPAHVWALGVGIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGP 94
Cdd:COG0531    8 ELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  95 LMAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGMQGQtglnqQPFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAI 174
Cdd:COG0531   88 LLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGS-----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 175 VALFVSVQFGASavPLDFSAITsdPLPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAAT 254
Cdd:COG0531  163 LLFIVVGLFAFD--PANFTPFL--PAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 255 MTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPV 334
Cdd:COG0531  239 LVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPR 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 335 YRTPYRAIVFLVPIALIFAL--GAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFhPLPTVVLLILC 412
Cdd:COG0531  319 FGTPVNAILLTGVIALLLLLlgAASFTALASLASVGVLLAYLLVALAVIVLRRRRP--DLPRPFRVPL-PLIPILGILLC 395

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 489628083 413 StayFAVFLGYGTQLSAMMCFYIVASLWFHFRRYK 447
Cdd:COG0531  396 L---FLLYLLGPGALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
15-447 2.14e-55

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 190.49  E-value: 2.14e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  15 RLLRVLGPAHVWALGVGIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGP 94
Cdd:COG0531    8 ELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  95 LMAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGMQGQtglnqQPFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAI 174
Cdd:COG0531   88 LLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGS-----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 175 VALFVSVQFGASavPLDFSAITsdPLPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAAT 254
Cdd:COG0531  163 LLFIVVGLFAFD--PANFTPFL--PAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 255 MTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPV 334
Cdd:COG0531  239 LVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPR 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 335 YRTPYRAIVFLVPIALIFAL--GAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFhPLPTVVLLILC 412
Cdd:COG0531  319 FGTPVNAILLTGVIALLLLLlgAASFTALASLASVGVLLAYLLVALAVIVLRRRRP--DLPRPFRVPL-PLIPILGILLC 395

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 489628083 413 StayFAVFLGYGTQLSAMMCFYIVASLWFHFRRYK 447
Cdd:COG0531  396 L---FLLYLLGPGALLIGLVLLAIGLLLYLLYRRR 427
2A0305 TIGR00908
ethanolamine permease; The three genes used as the seed for this model (from Burkholderia ...
 16-441 1.75e-40

ethanolamine permease; The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129986 [Multi-domain]  Cd Length: 442  Bit Score: 150.38  E-value: 1.75e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   16 LLRVLGPAHVWALGVGIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPL 95
Cdd:TIGR00908   5 LKKTLATWQLWGIGVGYVISGDYAGWNFGLAQGGWGGFVVATLLVATMYLTFCFSLAELSTMIPTAGGGYGFARRAFGPW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   96 MAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGmqgqTGLNQQPFIVLAIMFLAwLNYRGVLATLTFNLVITAIAFLAIV 175
Cdd:TIGR00908  85 GGFLAGTAILIEFAFAPPAIACFIGAYCESLFP----VGPGWLAALVFYIVFIG-INILGVGEAAKLEFVVTAVAIIALG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  176 alfvsVQFGASAVPLDFSAITSDP-------LPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMT 248
Cdd:TIGR00908 160 -----VFIGAMVPHFDSANLFNGPqtgassfLPGAYVGVFAAIPFAIWFFLAVEGVAMAAEETKNPKRDIPRGLIGAILT 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  249 LLIAATMTWYICSGLMPWEYLGQAGTPLFDAARVT--GSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPS 326
Cdd:TIGR00908 235 LLALAAGILVVGPGAADAKELMGSNNPLPEALESIygGSTWMSQFVNLVGLFGLIASFHGIIYGYSRQIFALSRAGYLPE 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  327 WFGAVHPvYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFHPLPTV 406
Cdd:TIGR00908 315 SLSKVNR-KKAPVLAIVVPGVIGFGLSLTGQTALIILVSVFGAIISYVLSMAAHFTLRIRRP--DMERPYRTPGGILTPG 391

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 489628083  407 VLLILCSTAYFAVFLGYGTQLSAMMCFYIVASLWF 441
Cdd:TIGR00908 392 VALVLACVALVTGFYVDPRVVVGAVAIFVVLIGYY 426
AA_permease pfam00324
Amino acid permease;
31-430 1.33e-14

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 75.82  E-value: 1.33e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   31 GIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPLMAFNVGL---FLVMA 107
Cdd:pfam00324   9 GVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGWnywLSWIT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  108 YTMLEAANAITVGFLLDTVAGMQGQTGlnqqpFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAIVALF-VSVQFGAS 186
Cdd:pfam00324  89 VLALELTAASILIQFWELVPDIPYLWV-----WGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIiVGIILLSG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  187 AVPLDFSAITS-------DPLPYGWV-GIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWY 258
Cdd:pfam00324 164 GNPNDGAIFRYlgdnggkNNFPPGFGkGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  259 ICSGLMPWEYLG------QAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFgAVH 332
Cdd:pfam00324 244 AIGLLVPWNDPGllndsaSAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFL-KKV 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  333 PVYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGY-TFMTFNMVM-----FRNKWPLGRIKR---GYVHPFHPL 403
Cdd:pfam00324 323 DKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLsGLIVWGLISlshlrFRKAFKYQGRSIdelPFKAPLGPL 402

                         410       420
                  ....*....|....*....|....*..
gi 489628083  404 PTVVLLILCSTAYFAVFLGYGTQLSAM 430
Cdd:pfam00324 403 GVILGLAAIIIILIIQFLYAFLPVPGG 429
frlA PRK11357
amino acid permease;
142-404 3.10e-12

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 68.34  E-value: 3.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 142 VLAIMFLAWLNYRGVLATLTFNLVITAIAFLAIVALFVSVQFGASAVPLDFSAITSDPLPYGWVGIVASLHFGLWYYLGI 221
Cdd:PRK11357 132 AGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGM 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 222 EGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVG--TAFA 299
Cdd:PRK11357 212 ASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAitAMIV 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 300 TLASANGCINDASRAWFSMSRDRYLPSWFGAVHPVYRTPYRAIVFLVPIALIFalgapldqvVTFSILSGLLGYtfmtFN 379
Cdd:PRK11357 292 ILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFF---------IFVSDLTSLLGY----FT 358

                        250       260       270
                 ....*....|....*....|....*....|
gi 489628083 380 MVM-FRNKWPLGRI----KRGYVHPFHPLP 404
Cdd:PRK11357 359 LVMcFKNTLTFGSIiwcrKRDDYKPLWRTP 388
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
15-447 2.14e-55

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 190.49  E-value: 2.14e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  15 RLLRVLGPAHVWALGVGIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGP 94
Cdd:COG0531    8 ELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  95 LMAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGMQGQtglnqQPFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAI 174
Cdd:COG0531   88 LLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGS-----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 175 VALFVSVQFGASavPLDFSAITsdPLPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAAT 254
Cdd:COG0531  163 LLFIVVGLFAFD--PANFTPFL--PAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 255 MTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPV 334
Cdd:COG0531  239 LVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPR 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 335 YRTPYRAIVFLVPIALIFAL--GAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFhPLPTVVLLILC 412
Cdd:COG0531  319 FGTPVNAILLTGVIALLLLLlgAASFTALASLASVGVLLAYLLVALAVIVLRRRRP--DLPRPFRVPL-PLIPILGILLC 395

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 489628083 413 StayFAVFLGYGTQLSAMMCFYIVASLWFHFRRYK 447
Cdd:COG0531  396 L---FLLYLLGPGALLIGLVLLAIGLLLYLLYRRR 427
2A0305 TIGR00908
ethanolamine permease; The three genes used as the seed for this model (from Burkholderia ...
 16-441 1.75e-40

ethanolamine permease; The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129986 [Multi-domain]  Cd Length: 442  Bit Score: 150.38  E-value: 1.75e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   16 LLRVLGPAHVWALGVGIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPL 95
Cdd:TIGR00908   5 LKKTLATWQLWGIGVGYVISGDYAGWNFGLAQGGWGGFVVATLLVATMYLTFCFSLAELSTMIPTAGGGYGFARRAFGPW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   96 MAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGmqgqTGLNQQPFIVLAIMFLAwLNYRGVLATLTFNLVITAIAFLAIV 175
Cdd:TIGR00908  85 GGFLAGTAILIEFAFAPPAIACFIGAYCESLFP----VGPGWLAALVFYIVFIG-INILGVGEAAKLEFVVTAVAIIALG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  176 alfvsVQFGASAVPLDFSAITSDP-------LPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMT 248
Cdd:TIGR00908 160 -----VFIGAMVPHFDSANLFNGPqtgassfLPGAYVGVFAAIPFAIWFFLAVEGVAMAAEETKNPKRDIPRGLIGAILT 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  249 LLIAATMTWYICSGLMPWEYLGQAGTPLFDAARVT--GSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPS 326
Cdd:TIGR00908 235 LLALAAGILVVGPGAADAKELMGSNNPLPEALESIygGSTWMSQFVNLVGLFGLIASFHGIIYGYSRQIFALSRAGYLPE 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  327 WFGAVHPvYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFHPLPTV 406
Cdd:TIGR00908 315 SLSKVNR-KKAPVLAIVVPGVIGFGLSLTGQTALIILVSVFGAIISYVLSMAAHFTLRIRRP--DMERPYRTPGGILTPG 391

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 489628083  407 VLLILCSTAYFAVFLGYGTQLSAMMCFYIVASLWF 441
Cdd:TIGR00908 392 VALVLACVALVTGFYVDPRVVVGAVAIFVVLIGYY 426
2A0306 TIGR00909
amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
 16-427 1.19e-23

amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129987 [Multi-domain]  Cd Length: 429  Bit Score: 102.91  E-value: 1.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   16 LLRVLGPAHVWALGVG-IVLVGEYMGWNFSVGKGGMiAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGP 94
Cdd:TIGR00909   1 LSRELGLFDLTMLGIGaMIGTGIFVVTGIAAGKAGP-AVILSFVLAGLTALFIALVYAELAAMLPVAGSPYTYAYEAMGE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   95 LMAFNVGLFLVMAYTMLEAANAIT-----------VGFLLDTVAGMQGQTGLNQQPFIVLAIMFLAWLNYRGVLATLTFN 163
Cdd:TIGR00909  80 LTAFIIGWSLWLEYGVAVAAVAVGwggylqeflpgVGLDLPAVLTAKPGNGGVFNLPALLIVLFLTYILYLGAKESGKVN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  164 LVITaiaFLAIVALFVSVQFGASAVpLDFSAITSDPLPYGWVGIVASLHFglWYYLGIEGTCQAAEEVRSPARSLPYGTM 243
Cdd:TIGR00909 160 DILV---VLKVAALLLFAALGAIHF-ASNNYTPFMPMGFGGVGAATALVF--FAFIGFEAISTAAEEVKNPERDIPKAII 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  244 AGIMTLLIAATMTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRY 323
Cdd:TIGR00909 234 LSLIVVTLLYVLVAAVILGAVPWRQLAGSTAPLSLVGYDLGQGIGGLILTAGAVFSIASVMLAGIYGTSRVLFAMSRDGL 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  324 LPSWFGAVHPVYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGYTFMTFNMVMFRNKWPlgRIKRGYVHPFHPL 403
Cdd:TIGR00909 314 LPGSLSKVHPKTGTPHMSIIIFSLTAALLASLVPLEGLAELTSIGTLIAFAAVNVAVIILRRRRP--DIQRAFRCPLVPV 391

                         410       420
                  ....*....|....*....|....
gi 489628083  404 PTVVLLILCstAYFAVFLGYGTQL 427
Cdd:TIGR00909 392 LPVLVVSYC--IYLLLNLGPGTTV 413
AA_permease pfam00324
Amino acid permease;
31-430 1.33e-14

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 75.82  E-value: 1.33e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   31 GIVLVGEYMGWNFSVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPLMAFNVGL---FLVMA 107
Cdd:pfam00324   9 GVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGWnywLSWIT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  108 YTMLEAANAITVGFLLDTVAGMQGQTGlnqqpFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAIVALF-VSVQFGAS 186
Cdd:pfam00324  89 VLALELTAASILIQFWELVPDIPYLWV-----WGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIiVGIILLSG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  187 AVPLDFSAITS-------DPLPYGWV-GIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWY 258
Cdd:pfam00324 164 GNPNDGAIFRYlgdnggkNNFPPGFGkGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  259 ICSGLMPWEYLG------QAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFgAVH 332
Cdd:pfam00324 244 AIGLLVPWNDPGllndsaSAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFL-KKV 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  333 PVYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGY-TFMTFNMVM-----FRNKWPLGRIKR---GYVHPFHPL 403
Cdd:pfam00324 323 DKRGVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLsGLIVWGLISlshlrFRKAFKYQGRSIdelPFKAPLGPL 402

                         410       420
                  ....*....|....*....|....*..
gi 489628083  404 PTVVLLILCSTAYFAVFLGYGTQLSAM 430
Cdd:pfam00324 403 GVILGLAAIIIILIIQFLYAFLPVPGG 429
AA_permease_2 pfam13520
Amino acid permease;
44-417 1.04e-12

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 69.65  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   44 SVGKGGMIAGLMACWVAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPLMAFNVGLFLVMAY-TMLEAANAITVGFL 122
Cdd:pfam13520  24 LVASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYvLGLASSASVAASYL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  123 LDTVAGMQGQTGLNQQPFIVLAIMFLAWLNYRGVLATLTFNLVITAIAFLAIVALFVSVQFGASA--VPLDFSAITSDPL 200
Cdd:pfam13520 104 LSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILIIILGLVTADggGFNLLSGEWHTFF 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  201 PYGWVGIVASLHFGLWYYLGIEGTCQAAEEVrsPARSLPYGTMAGI---MTLLIAATMTWYICSGLMPWEYLGQAGTPLF 277
Cdd:pfam13520 184 PDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGViivGVLYILVNIAFFGVVPDDEIALSSGLGQVAA 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  278 DAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLP--SWFGAVHPvYRTPYRAIVFLVPIALIFALG 355
Cdd:pfam13520 262 LLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPfsRFFAKVNK-FGSPIRAIILTAILSLILLLL 340

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489628083  356 APLDQVVtFSILSGLLGYTFMTFNMVMF-------RNKWPLGRIKRGYvhPFHPLPTVVLLILCSTAYF 417
Cdd:pfam13520 341 FLLSPAA-YNALLSLSAYGYLLSYLLPIigllilrKKRPDLGRIPGRW--PVAIFGILFSLFLIVALFF 406
frlA PRK11357
amino acid permease;
142-404 3.10e-12

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 68.34  E-value: 3.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 142 VLAIMFLAWLNYRGVLATLTFNLVITAIAFLAIVALFVSVQFGASAVPLDFSAITSDPLPYGWVGIVASLHFGLWYYLGI 221
Cdd:PRK11357 132 AGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGM 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 222 EGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWYICSGLMPWEYLGQAGTPLFDAARVTGSTGLMVLLFVG--TAFA 299
Cdd:PRK11357 212 ASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAitAMIV 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 300 TLASANGCINDASRAWFSMSRDRYLPSWFGAVHPVYRTPYRAIVFLVPIALIFalgapldqvVTFSILSGLLGYtfmtFN 379
Cdd:PRK11357 292 ILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFF---------IFVSDLTSLLGY----FT 358

                        250       260       270
                 ....*....|....*....|....*....|
gi 489628083 380 MVM-FRNKWPLGRI----KRGYVHPFHPLP 404
Cdd:PRK11357 359 LVMcFKNTLTFGSIiwcrKRDDYKPLWRTP 388
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 92-384 4.62e-12

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 67.92  E-value: 4.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   92 VGPLMAFNVGLFLVMAYTMLEAANAITVGFLLDTVAGMQ-----------GQTGLNQQP--FIVLAIMFLAWLNYRGVLA 158
Cdd:TIGR00906 103 VGELWAFITGWNLILEYVIGTAAVARSWSAYFDELLNKQigqfrrtyfklNYDGLAEYPdfFAVCLILLLAVLLSFGVKE 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  159 TLTFNLVITAIAFLAIVALFVS--VQFGASAVPLDFSAITSDPLPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPAR 236
Cdd:TIGR00906 183 SAWVNKIFTAINILVLLFVIIAgfTKADVANWSITEEKGAGGFMPYGFTGVLSGAATCFFAFIGFDAIATTGEEVKNPQR 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  237 SLPYGTMAGIMTLLIAATMTWYICSGLMPWeYLGQAGTPLFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWF 316
Cdd:TIGR00906 263 AIPIGIVTSLLVCFVAYFLMSAALTLMMPY-YLLDPDAPFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMFPLPRVIY 341

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489628083  317 SMSRDRYLPSWFGAVHPVYRTPYRAIVFLVPIALIFALGAPLDQVVTFSILSGLLGYTFMTFNMVMFR 384
Cdd:TIGR00906 342 AMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAYSLVAACVLILR 409
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 59-353 5.40e-09

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 58.22  E-value: 5.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083   59 VAGLLYTCVAMIDSEVTSTVAAAGGQYAQAKHIVGPLMAF-NVGLFLVMAYTMLEAANAITVG-FLLDTVAGMQGQTGLN 136
Cdd:TIGR00911  85 VCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGPLLAFlRLWIELLVIRPGSQAVNALNFAiYILTPVFPDCEVPEWA 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  137 QQPFIVLAIMFLAWLNYRGVLATLTFNLVITA--IAFLAIVALFVSVQFGASAVP-LDF--SAITSDPLPYGWVgivASL 211
Cdd:TIGR00911 165 IRLVAVLCVLLLTLVNCLSVKWATRVQDIFTAckLLALLLIIITGWVQLGKGGVEsLNPknAFEGTETSAGGIV---LAF 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  212 HFGLWYYLGIEGTCQAAEEVRSPARSLPygtMAGIMTLLIAATMtwYICSG------LMPWEYLGQAGTPLFDAARVTGS 285
Cdd:TIGR00911 242 YSGIWAYGGWNYLNFVTEEVKNPYRTLP---IAIIISMPIVTFI--YVLTNiayftvLSPEELLASLAVAVDFGERLLGV 316

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489628083  286 TGLMVLLFVGtaFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPVYRTPYRAIVFLVPIALIFA 353
Cdd:TIGR00911 317 MSWAMPALVG--LSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLML 382
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 205-447 5.73e-05

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 45.35  E-value: 5.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  205 VGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWYICSGLMPWE---------YLGQAGTP 275
Cdd:TIGR00913 197 KGVCSVFVTAAFSFGGTELVALTAGEAANPRKSIPRAAKRTFWRILVFYILTLFLIGFLVPYNdprllssssSSDSAASP 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  276 LFDAARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPVYRtPYRAIVFLVPIALIFALG 355
Cdd:TIGR00913 277 FVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRTLYALAHQGLAPKIFAYVDRRGV-PYVAVIVSSLFGLLAFLA 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083  356 APLDQVVTF------SILSGLLGYTFMTFNMVMFRNKWPL-GRIKR--GYVHPFHPLPTVVLLILCS--------TAYFA 418
Cdd:TIGR00913 356 VSKKEAEVFtwllniSGLSGFFTWMCICLSHIRFRKAMKAqGRSLDelPYKSQTGPYGSYYALFFNIliliaqgyVAFAP 435

                         250       260
                  ....*....|....*....|....*....
gi 489628083  419 VFLGYGTQLSAMMCFYIVASLWFHFRRYK 447
Cdd:TIGR00913 436 VKFSAKSFFEAYLSLPIFIALYIGHKVYK 464
PRK10238 PRK10238
aromatic amino acid transporter AroP;
200-431 3.43e-04

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 43.02  E-value: 3.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 200 LPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPYGTMAGIMTLLIAATMTWYICSGLMPWEYLGQAGTPLFDA 279
Cdd:PRK10238 195 LPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLI 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 280 ARVTGSTGLMVLLFVGTAFATLASANGCINDASRAWFSMSRDRYLPSWFGAVHPvYRTPYRAIVFLVPIALIFALGAPLD 359
Cdd:PRK10238 275 FHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDK-RGVPVNTILVSALVTALCVLINYLA 353

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489628083 360 QVVTFSILSGL------LGYTFMTFNMVMFRNKWPLGRIKRGYVHPFHPLPTVVLLILCSTAYFAVFLGYGTQLSAMM 431
Cdd:PRK10238 354 PESAFGLLMALvvsalvINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYL 431
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
165-451 2.98e-03

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 39.77  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 165 VITAIAFLAIVALFVSVQFGASAVPLDFSAITSDPLPYGWVGIVASLHFGLWYYLGIEGTCQAAEEVRSPARSLPY---G 241
Cdd:COG0833  161 VITVIAFIIVGLLMIFGIIGGHAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKairQ 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 242 TMAGIMTLLIAATmtwYICSGLMPWEYLGQAGTP---LFDAARVTGSTGLM--VLLFvgtafATLASANGCINDASRAWF 316
Cdd:COG0833  241 VFWRILLFYILAI---FVIAALIPYTDAGVAESPftlVFERAGIPYAADIMnaVILT-----AVLSAGNSGLYASTRMLW 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489628083 317 SMSRDRYLPSWFGAVHPvYRTPYRAIVF---LVPIALIFALGAPlDQVVTF----SILSGLLGYTFMTFNMVMFRNKWpl 389
Cdd:COG0833  313 SLAKEGMAPKIFAKLNK-RGVPLNALLAtmaVGLLALLSSFFGA-GTVYLWllsiSGLTGFIAWLGIAISHYRFRRAY-- 388

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489628083 390 grIKRG-------YVHPFHPLPTVVLLILCSTAYFAVFLGYGTQLSAMMCFYIVASLWFHfrrYKFVRR 451
Cdd:COG0833  389 --VAQGgdledlkYKAPLFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLG---YKLKKK 452
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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