|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-427 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 741.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 EELRGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRER 159
Cdd:PRK01117 81 KEIDELEARGVdVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 160 LTTVLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 240 SSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAAR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 320 IGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKR 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420
....*....|....*....|....*...
gi 489705559 400 VEELIGVPLYTFAVGPSNEQTIILFDIW 427
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 730.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:COG0104 2 VVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:COG0104 82 DGLEARGVdVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:COG0104 162 LLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:COG0104 242 TAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRING 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEE 402
Cdd:COG0104 322 LTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIEE 401
|
410 420
....*....|....*....|.
gi 489705559 403 LIGVPLYTFAVGPSNEQTIIL 423
Cdd:COG0104 402 LLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-421 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 711.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEELR 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTTV 163
Cdd:pfam00709 81 ELEERGIdVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 164 LAEKNELLEKIYnHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSPV 243
Cdd:pfam00709 161 LELKNKLLEKLY-GEPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 244 GGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGGF 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 324 THLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*...
gi 489705559 404 IGVPLYTFAVGPSNEQTI 421
Cdd:pfam00709 400 LGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-422 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 666.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:smart00788 2 VVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKgdgkIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:smart00788 82 EELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:smart00788 158 LLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:smart00788 238 TAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRING 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEE 402
Cdd:smart00788 318 ITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIEE 397
|
410 420
....*....|....*....|
gi 489705559 403 LIGVPLYTFAVGPSNEQTII 422
Cdd:smart00788 398 LVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-425 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 537.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEELR 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKGVTT-DNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTTV 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 164 LAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSPV 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 244 GGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGGF 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 324 THLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|..
gi 489705559 404 IGVPLYTFAVGPSNEQTIILFD 425
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRK 422
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
4-422 |
2.19e-165 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 467.36 E-value: 2.19e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:cd03108 3 TVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEEI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDlldeavlrerltt 162
Cdd:cd03108 83 EELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 vlaeknellekiynhepldldelvaeftdygqqlkPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVlsglktlkiavayeldgqriehypaslgdvrrvtpiyeelpgwddditgvksreelpaNAEAYLKRVEE 402
Cdd:cd03108 275 LTELALTKLDV----------------------------------------------------------NAQKYIERIEE 296
|
410 420
....*....|....*....|
gi 489705559 403 LIGVPLYTFAVGPSNEQTII 422
Cdd:cd03108 297 LLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-322 |
5.68e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.94 E-value: 5.68e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQ--NSDMVVRyQGGNNAGHTIYVD-GQKFELSAIPSGIFNPNRLAV-IGNGSVVNPKAL 79
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGYLAEraAPDVVVR-AAGPNAGHTYIDDeGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 80 LEELRGIQEKG-VTTDNLRISDRAHVIfPYHILIDQLAdarKGDGKIGTTGRGIGPTYMDKAARTGirvvDLLDEAVLRE 158
Cdd:NF038379 81 REEIEELEDAGhDVGKRLLIHEQATVI-ELHKHVEEEA---GPMTKIGSTKKGIGAARAAKIRRNP----STLGDAEGDF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 159 RLTTVLAEKNELLEKIYNHEpLDLDElvaeftdygqqlkpyitdttvivneyLDSNKRVLLEGAQGAMLDIDHGTYPYVT 238
Cdd:NF038379 153 GEGAVRDQPWEIAERVVDNA-LYDFA--------------------------LQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 239 SS--SPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGD-----GPFPTEL-FDEVGdrireIGHEYGVVTKRPRRIGWLD 310
Cdd:NF038379 206 SRdcTPADFLADAGIPLPNVDAFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 489705559 311 TVVLRHAARIGG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-427 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 741.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 EELRGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRER 159
Cdd:PRK01117 81 KEIDELEARGVdVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 160 LTTVLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 240 SSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAAR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 320 IGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKR 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420
....*....|....*....|....*...
gi 489705559 400 VEELIGVPLYTFAVGPSNEQTIILFDIW 427
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 730.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:COG0104 2 VVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:COG0104 82 DGLEARGVdVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:COG0104 162 LLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:COG0104 242 TAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRING 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEE 402
Cdd:COG0104 322 LTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIEE 401
|
410 420
....*....|....*....|.
gi 489705559 403 LIGVPLYTFAVGPSNEQTIIL 423
Cdd:COG0104 402 LLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-421 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 711.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEELR 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTTV 163
Cdd:pfam00709 81 ELEERGIdVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 164 LAEKNELLEKIYnHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSPV 243
Cdd:pfam00709 161 LELKNKLLEKLY-GEPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 244 GGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGGF 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 324 THLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*...
gi 489705559 404 IGVPLYTFAVGPSNEQTI 421
Cdd:pfam00709 400 LGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-422 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 666.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:smart00788 2 VVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKgdgkIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:smart00788 82 EELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:smart00788 158 LLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSNT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:smart00788 238 TAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRING 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEE 402
Cdd:smart00788 318 ITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIEE 397
|
410 420
....*....|....*....|
gi 489705559 403 LIGVPLYTFAVGPSNEQTII 422
Cdd:smart00788 398 LVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-425 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 537.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEELR 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKGVTT-DNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTTV 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 164 LAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSPV 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 244 GGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGGF 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 324 THLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVEEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|..
gi 489705559 404 IGVPLYTFAVGPSNEQTIILFD 425
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRK 422
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
5-424 |
6.26e-179 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 506.10 E-value: 6.26e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIY-VDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:PLN02513 6 AVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGLFEEI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGVTTDN-LRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:PLN02513 86 DGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAEKLRE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKiYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:PLN02513 166 LLADAAARFEG-FEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVTSSNP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:PLN02513 245 SAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSCQING 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYEL-DGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVE 401
Cdd:PLN02513 325 FTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYVERIE 404
|
410 420
....*....|....*....|...
gi 489705559 402 ELIGVPLYTFAVGPSNEQTIILF 424
Cdd:PLN02513 405 ELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
5-422 |
1.55e-172 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 489.92 E-value: 1.55e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEELR 84
Cdd:PTZ00350 16 VILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEIE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKGVT-TDNLRISDRAHVIFPYHILIDQLADARKGDG--KIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLT 161
Cdd:PTZ00350 96 QLTKKGINlLGRLYISDRAHLVFDLHQAIDGIQESEKGKGgtQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKYR 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 162 TVLAEKNELlekiYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSS 241
Cdd:PTZ00350 176 KLVEKLQEQ----YNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSSN 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 242 PVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIG 321
Cdd:PTZ00350 252 TTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQMIN 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 322 GFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIE--HYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKR 399
Cdd:PTZ00350 332 GFDSINLTKLDVLSGLKEIKICVNYKNKGTGLEigRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKYVLF 411
|
410 420
....*....|....*....|...
gi 489705559 400 VEELIGVPLYTFAVGPSNEQTII 422
Cdd:PTZ00350 412 IEELLGVPIVWIGVGPNRENMIV 434
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
4-422 |
2.19e-165 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 467.36 E-value: 2.19e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:cd03108 3 TVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEEI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGV-TTDNLRISDRAHVIFPYHILIDQLADARKGDGKIGTTGRGIGPTYMDKAARTGIRVVDlldeavlrerltt 162
Cdd:cd03108 83 EELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 vlaeknellekiynhepldldelvaeftdygqqlkPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSSP 242
Cdd:cd03108 150 -----------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSNT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:cd03108 195 TAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRING 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVlsglktlkiavayeldgqriehypaslgdvrrvtpiyeelpgwddditgvksreelpaNAEAYLKRVEE 402
Cdd:cd03108 275 LTELALTKLDV----------------------------------------------------------NAQKYIERIEE 296
|
410 420
....*....|....*....|
gi 489705559 403 LIGVPLYTFAVGPSNEQTII 422
Cdd:cd03108 297 LLGVPITYISVGPDREQTII 316
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-420 |
6.81e-145 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 418.83 E-value: 6.81e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 EELRGIQEKGVTTDnLRISDRAHVIFPYHilidQLADARKGdgKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERL 160
Cdd:PRK13788 81 EERENLRAGGLNPK-LLISERAHLVLPHH----KYVDGRKN--FVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 161 TTVLAEK-NELLEKIYNHEpldlDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTS 239
Cdd:PRK13788 154 ERLLEAKpNSTREAGWDTV----EKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 240 SSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIG----HEYGVVTKRPRRIGWLDTVVLR 315
Cdd:PRK13788 230 SHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 316 HAARIGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQriehypaslgdvrrvtPIYEELPGWdDDITGVKSREELPANAEA 395
Cdd:PRK13788 310 YACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDGQ----------------PVYKELPGW-GDLDGVKSREALPKEAQA 372
|
410 420
....*....|....*....|....*
gi 489705559 396 YLKRVEELIGVPLYTFAVGPSNEQT 420
Cdd:PRK13788 373 YLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-421 |
1.52e-144 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 418.43 E-value: 1.52e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 5 VVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLaVIGNGSVVNPKALLEELR 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 85 GIQEKG--VTTDNLRISDRAHVIFPYHILIDQLADARKGDgKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:PRK13786 83 MLEKHGvkVDAEKLGIDAKTSIIMPYHIELDGLRESARTE-KIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNELLEKIYNHEPLDLDE-LVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVTSSS 241
Cdd:PRK13786 162 LAPQKEKEIKELGGDPSIVRDEaLIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTSSS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 242 PVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIG 321
Cdd:PRK13786 242 TIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIYLN 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 322 GFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLKRVE 401
Cdd:PRK13786 322 GYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVERLE 401
|
410 420
....*....|....*....|
gi 489705559 402 ELIGVPLYTFAVGPSNEQTI 421
Cdd:PRK13786 402 ELMGVPIKYISVGPGREQTF 421
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
4-423 |
7.85e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 404.91 E-value: 7.85e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNpNRLAVIGNGSVVNPKALLEEL 83
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVR-GKIGVLGNGCVVNPETLFDEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGVTTDnLRISDRAHVIFPYHILIDQLADARKG--DGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLT 161
Cdd:PRK13785 82 DALRERGLDPD-VRVAERAHVILPYHRVLDGIEEEAKSdsDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 162 TVLAEKNELLEKIYN------HEPLDLDELVAEFTDYGQQLKPyiTDTTVIVNEYL----DSNKRVLLEGAQGAMLDIDH 231
Cdd:PRK13785 161 YVVPQKRALAEDVYGldasetPEAFDVDALFEEYREYGERLAE--EDMTVNAGDFLaeriDDGDNVMLEGAQGTSIDIDH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 232 GTYPYVTSSSPVGGGATIGAGIGPTKIDR--VVGVAKAYTSRVGDGPFPTEL---------------FDEVGDRIREIGH 294
Cdd:PRK13785 239 GNYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 295 EYGVVTKRPRRIGWLDTVVLRHAARIGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASLGDVRRVTPIYEELP 374
Cdd:PRK13785 319 EYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 489705559 375 GWDD-DITGVKSR--EELPANAEAYLKRVEELIGVPLYTFAVGPSNEQTIIL 423
Cdd:PRK13785 399 GWPEvDWAAVAEEgyDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-423 |
8.65e-135 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 393.55 E-value: 8.65e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 EELRGIQEKGVTT-DNLRISDRAHVIFPYHILIDQLADARKG-DGKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAvLRE 158
Cdd:PRK13787 81 EECDRLQKEGFPVkDKLLLSDACHLLFPYHSQIDSARETTSSqEHKIGTTKKGIGICYADKMMRTGLRVGDLLDKS-YKR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 159 RLTTVLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVT 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 239 SSSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAA 318
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 319 RIGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHYPASlgDVRRVTPIYEELPGWDDDITGVKSREELPANAEAYLK 398
Cdd:PRK13787 320 RINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQ--GLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|....*
gi 489705559 399 RVEELIGVPLYTFAVGPSNEQTIIL 423
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
4-421 |
2.56e-126 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 371.36 E-value: 2.56e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALLEEL 83
Cdd:PRK13783 3 RVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEEL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 84 RGIQEKGVT-TDNLRISDRAHVIFPYHILIDQLADARKGDgKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRERLTT 162
Cdd:PRK13783 83 EELKEKFPDySGRIFISELAHVVLPVHKELDEIIESVRKN-AIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLEK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 163 VLAEKNelleKIYNHEpLDLDELVAEFTDYGQQLKPYITDTTVIVNEYldSNKRVLLEGAQGAMLDIDHGTYPYVTSSSp 242
Cdd:PRK13783 162 ILSLYK----KLYGIE-FDVEKMMEDLLTFYEKIKDLVVSPVEIKRIL--EEKSVLFEGTQGVLLDLDVGTYPYVTSSN- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 243 VGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAARIGG 322
Cdd:PRK13783 234 CSTTGVSAGMGFPVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVSG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 323 FTHLSLNSLDVLSGLKTLKIAVAYELDGQRIEHyPASLGDVRRVTPIYEELPGWddditgvKSREElpANAEAYLKRVEE 402
Cdd:PRK13783 314 VDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGW-------KSLED--KNFLKFVDFIER 383
|
410
....*....|....*....
gi 489705559 403 LIGVPLYTFAVGPSNEQTI 421
Cdd:PRK13783 384 ETGRKIAYISTGPKIEEIV 402
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-430 |
6.39e-117 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 348.16 E-value: 6.39e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQNSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 EELRGIQEKGV--TTDNLRISDRAHVIFPYHILIDQLADARKGDgKIGTTGRGIGPTYMDKAARTGIRVVDLLDEAVLRE 158
Cdd:PRK13784 81 EEITRLQAKGIaiSAENLFVSESCTIITSYHKLLDAVRESNTSE-KIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 159 RLTTVLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTYPYVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 239 SSSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIGHEYGVVTKRPRRIGWLDTVVLRHAA 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 319 RIGGFTHLSLNSLDVLSGLKTLKIAVAYELDGQRIehYPASLG-DVRRVTPIYEELPGWDDDitGVKSREELPANAEAYL 397
Cdd:PRK13784 320 KCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI--YCAYPGiDLYKVEPILVEMEPFSID--ETVTKDNMPAALKTYL 395
|
410 420 430
....*....|....*....|....*....|...
gi 489705559 398 KRVEELIGVPLYTFAVGPSNEQTIILFDIWNEG 430
Cdd:PRK13784 396 KTIENHVGIPISSLAYGPSREQILFFEDYFKKG 428
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-421 |
7.68e-71 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 226.69 E-value: 7.68e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 1 MAGIVVVGSQWGDEGKGKITNFIAQ--NSDMVVRYQGGNNAGHTIYVDGQKFELSAIPSGIFNPNRLAVIGNGSVVNPKA 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLALkdKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 79 LLEELrgiqEKGVTTDNLRISDRAHVIFPYHILIDqladarKGD----GKIGTTGRGIGPTYMDKAARTgirvvdlldea 154
Cdd:PRK04293 81 LLKEV----EELNVGGRVFVDYRCGIIEEKHVEED------RSDehlsKKIGSTGTGCGPANADRVLRR----------- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 155 vLRerlttvLAEknellekiynheplDLDELvaeftdygqqlKPYITDTTVIVNEYLDSNKRVLLEGAQGAMLDIDHGTY 234
Cdd:PRK04293 140 -LK------LAK--------------DVEEL-----------EKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTY 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 235 PYVTSSSPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGDGPFPTELFDEVGDRIREIghEYGVVTKRPRRIGWLDTVVL 314
Cdd:PRK04293 188 PYVTSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELA 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 315 RHAARIGGFTHLSLNSLDVLsglktlkiavayeldgqriehypaslgdvrrvtpiyeelpgwDDDITGVKSREELPANAE 394
Cdd:PRK04293 266 RRAARINGATQIAITKLDKL------------------------------------------DKEAYGVTEYDKLPPEAK 303
|
410 420
....*....|....*....|....*..
gi 489705559 395 AYLKRVEELIGVPLYTFAVGPSNEQTI 421
Cdd:PRK04293 304 KFIEEIEEELGVPVTLISTGPELEDTI 330
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-322 |
5.68e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.94 E-value: 5.68e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQ--NSDMVVRyQGGNNAGHTIYVD-GQKFELSAIPSGIFNPNRLAV-IGNGSVVNPKAL 79
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGYLAEraAPDVVVR-AAGPNAGHTYIDDeGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 80 LEELRGIQEKG-VTTDNLRISDRAHVIfPYHILIDQLAdarKGDGKIGTTGRGIGPTYMDKAARTGirvvDLLDEAVLRE 158
Cdd:NF038379 81 REEIEELEDAGhDVGKRLLIHEQATVI-ELHKHVEEEA---GPMTKIGSTKKGIGAARAAKIRRNP----STLGDAEGDF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 159 RLTTVLAEKNELLEKIYNHEpLDLDElvaeftdygqqlkpyitdttvivneyLDSNKRVLLEGAQGAMLDIDHGTYPYVT 238
Cdd:NF038379 153 GEGAVRDQPWEIAERVVDNA-LYDFA--------------------------LQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 239 SS--SPVGGGATIGAGIGPTKIDRVVGVAKAYTSRVGD-----GPFPTEL-FDEVGdrireIGHEYGVVTKRPRRIGWLD 310
Cdd:NF038379 206 SRdcTPADFLADAGIPLPNVDAFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 489705559 311 TVVLRHAARIGG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-423 |
2.04e-16 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 81.64 E-value: 2.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 4 IVVVGSQWGDEGKGKITNFIAQNS--DMVVRYQGGNNAGHTIYVD-GQKFELSAIPSGIFNPNRLAVIGNGSVVNPKALL 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHPlcTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 81 E-ELRGIQEKGVTTDNLRISDRAHVIFPYHILIDQLADARKgdgkiGTTGRGIGPTYMDKAARTGIRVVDLL-DEAVLRE 158
Cdd:PTZ00351 252 EkEIIQLIDAGIDYRDRLFIGNVCIVTPYHKLLDLLGSAAN-----SSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLRK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 159 RLTTVLAEKNELLeKIYNHEPLDLDEL--------VAEFTDYGQQLKPYITDTTVIVNEYLD------------------ 212
Cdd:PTZ00351 327 RLEKDMDTYLGLL-KVKNLSDADVVRLcreensdgVVRVPDYVIAFAQAKDKVEFLVKLYRDrvrhnpdfparcdvtyel 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 213 -----SNKRVLLEGAQGAML-DIDHGTYPYVTSSSPVGGGATIGAGIGPTKIDRVV-GVAKAY-TSRVGDG--------- 275
Cdd:PTZ00351 406 haavlRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGacpssfvpq 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 276 ----------------------------------PF------------PTELFDEVGD-------RIREIGH--EYGVVT 300
Cdd:PTZ00351 486 dyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDynigvamAIASAQHhgECGAVT 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489705559 301 KRPRRIGWLDTVVLRHAARIGGfTHLSLNSLDVLSGLKTLKIAVA---YELDGQRIE--HYPASLGDVRRVT-------- 367
Cdd:PTZ00351 566 KKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAyvyYNPEGKQVDvnGHVYKNGDIIRAGdpvpsepa 644
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489705559 368 -----PIYEELPGW-DDDITGVKSREE--LPANAEAYLKRVEELIGVPLYTFAVGPSNEQTIIL 423
Cdd:PTZ00351 645 lyhchPIVKLIDGWrDNPIAAAKRRRNapLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYL 708
|
|
| Slx4 |
pfam09494 |
Slx4 endonuclease; The Slx4 protein is a heteromeric structure-specific endonuclease found ... |
158-214 |
1.89e-04 |
|
Slx4 endonuclease; The Slx4 protein is a heteromeric structure-specific endonuclease found from fungi to mammals. Slx4 with Slx1 acts as a nuclease on branched DNA substrates, particularly simple-Y, 5'-flap, or replication fork structures by cleaving the strand bearing the 5' non-homologous arm at the branch junction and thus generating ligatable nicked products from 5'-flap or replication fork substrates.
Pssm-ID: 430644 Cd Length: 60 Bit Score: 39.03 E-value: 1.89e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 489705559 158 ERLTTVLAEKNELLEKIYNHEPLDLDELVAEFTDYGQQLKpyITDTTVIvnEYLDSN 214
Cdd:pfam09494 2 EAITELIKSDPSLYEKILTYEPIVLEDLTAWLNEGGFLIE--VDPGTLK--EWCDSQ 54
|
|
| |
