|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-387 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 773.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 1 MNTSDLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDAGIVTFDV 80
Cdd:PRK05322 1 MMKEELKKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFEDLGIIEFDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 81 NDLSYDKAAGWTNYPKGMMDEIAKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQK 160
Cdd:PRK05322 81 DDLSFDKEDDWANYPKGVLKFLQEAGYKIDHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 161 CENNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQT 240
Cdd:PRK05322 161 TENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGDYVIVIMNTNKRRELADSKYNERRAECEKALEELQK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 241 KLDIKSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDT 320
Cdd:PRK05322 241 KLDIKSLGELTEEEFDEYSYLIKDETLLKRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVSLRDDYEVTGLELDT 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489738969 321 LAETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:PRK05322 321 LVEAAWKQEGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAYEEKIGYAASFYVAEIGDGAREL 387
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
5-387 |
0e+00 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 584.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 5 DLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDagIVTFDVNDLS 84
Cdd:COG0153 4 RLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFDE--EVEFDLDDLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 85 YDKAAGWTNYPKGMMDEIAKTGVKFdHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENN 164
Cdd:COG0153 82 PGEEDGWANYVRGVAWALQERGYKL-GGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAENE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 165 YVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRrlqtKLDI 244
Cdd:COG0153 161 FVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYALVIVDTNVKHSLADSEYNERRAECEAAAA----ILGV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 245 KSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAET 324
Cdd:COG0153 237 KSLRDVTLEDLEAARARLGDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVEL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489738969 325 AWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:COG0153 317 ALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
6-387 |
2.51e-130 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 379.17 E-value: 2.51e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 6 LKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIpDAGIVTFDVNDLSY 85
Cdd:TIGR00131 4 IQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANA-DNKFAERSLDLPLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 86 DK-AAGWTNYPKGMMDEIAKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENN 164
Cdd:TIGR00131 83 GSeVSDWANYFKGVLHVAQERFNSFPLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAENH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 165 YVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQTKlDI 244
Cdd:TIGR00131 163 FVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAAT-DK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 245 KSLGDLTNDQFD--EAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLA 322
Cdd:TIGR00131 242 GALRDFMNEYFAryIARLTKMLPLVEERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELV 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489738969 323 ETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:TIGR00131 322 CSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPGAGSC 386
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
8-57 |
1.98e-23 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 91.75 E-value: 1.98e-23
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 489738969 8 QEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAP 57
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-387 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 773.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 1 MNTSDLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDAGIVTFDV 80
Cdd:PRK05322 1 MMKEELKKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFEDLGIIEFDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 81 NDLSYDKAAGWTNYPKGMMDEIAKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQK 160
Cdd:PRK05322 81 DDLSFDKEDDWANYPKGVLKFLQEAGYKIDHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 161 CENNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQT 240
Cdd:PRK05322 161 TENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGDYVIVIMNTNKRRELADSKYNERRAECEKALEELQK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 241 KLDIKSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDT 320
Cdd:PRK05322 241 KLDIKSLGELTEEEFDEYSYLIKDETLLKRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVSLRDDYEVTGLELDT 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489738969 321 LAETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:PRK05322 321 LVEAAWKQEGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAYEEKIGYAASFYVAEIGDGAREL 387
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
5-387 |
0e+00 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 584.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 5 DLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDagIVTFDVNDLS 84
Cdd:COG0153 4 RLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFDE--EVEFDLDDLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 85 YDKAAGWTNYPKGMMDEIAKTGVKFdHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENN 164
Cdd:COG0153 82 PGEEDGWANYVRGVAWALQERGYKL-GGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAENE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 165 YVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRrlqtKLDI 244
Cdd:COG0153 161 FVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYALVIVDTNVKHSLADSEYNERRAECEAAAA----ILGV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 245 KSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAET 324
Cdd:COG0153 237 KSLRDVTLEDLEAARARLGDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVEL 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489738969 325 AWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:COG0153 317 ALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
6-387 |
2.51e-130 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 379.17 E-value: 2.51e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 6 LKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIpDAGIVTFDVNDLSY 85
Cdd:TIGR00131 4 IQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANA-DNKFAERSLDLPLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 86 DK-AAGWTNYPKGMMDEIAKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENN 164
Cdd:TIGR00131 83 GSeVSDWANYFKGVLHVAQERFNSFPLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAENH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 165 YVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQTKlDI 244
Cdd:TIGR00131 163 FVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAAT-DK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 245 KSLGDLTNDQFD--EAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLA 322
Cdd:TIGR00131 242 GALRDFMNEYFAryIARLTKMLPLVEERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELV 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489738969 323 ETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL 387
Cdd:TIGR00131 322 CSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPGAGSC 386
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
4-383 |
3.10e-117 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 345.75 E-value: 3.10e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 4 SDLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIpDAGIVTFDVND- 82
Cdd:PRK05101 5 QKTQSLFAQQFGYPPTHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRIVRVIAADY-DNQQDEFSLDAp 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 83 LSYDKAAGWTNYPKGMMDEIAKTGVKFdHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCE 162
Cdd:PRK05101 84 IVPHPEQQWANYVRGVVKHLQERNPDF-GGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQEAE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 163 NNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVkLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQtkl 242
Cdd:PRK05101 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPM-PEGVAVVIINSNVKRGLVDSEYNTRRQQCETAARFFG--- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 243 dIKSLGDLTNDQFDEAAYLInDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLA 322
Cdd:PRK05101 239 -VKALRDVTLEQFNAVAAEL-DPVVAKRARHVITENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDTLV 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489738969 323 ETAwkqPGVL----GARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADG 383
Cdd:PRK05101 317 EIV---KAVIgdqgGVRMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKTGLKETFYVCKASQG 378
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
24-383 |
5.92e-111 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 328.49 E-value: 5.92e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 24 SPGRINLIGEHTDYNGGHVFPCAITIGTygVYAPRTDTTVRMYSANIPDAGIVTFDvndlSYDKAAGWTNYPKGMMDEIA 103
Cdd:PRK03817 5 SPGRVNLIGEHTDYNDGYVLPFAINLYT--FLEIEKSEKFIFYSENFNEEKTFELD----KLEKLNSWADYIKGVIWVLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 104 KTGVKFDhGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENNYVGVNSGIMDQFAVGMGKK 183
Cdd:PRK03817 79 KRGYEVG-GVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENEFVGVPCGIMDQFAVAFGKK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 184 DQAILLDTNTMDYSYAPVKLGNNVIVImNTNKRRELADSKYNERRSECEEALRrlqtKLDIKSLGDLTNDQFDEAaylin 263
Cdd:PRK03817 158 DHAIFLDTMTLEYEYVPFPEDYEILVF-DTGVKRELASSEYNERRQECEEALK----ILGKKSSKEVTEEDLSKL----- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 264 DETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAETAwKQPGVLGARMTGAGFGG 343
Cdd:PRK03817 228 PPLLRKRAGYVLRENERVLKVRDALKEGDIETLGELLTESHWDLADNYEVSCEELDFFVEFA-LELGAYGARLTGAGFGG 306
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 489738969 344 CGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADG 383
Cdd:PRK03817 307 SAIALVDKGKFESIGEELLEEYKKRFGIDPKYFVVESSDG 346
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
22-361 |
7.89e-66 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 213.18 E-value: 7.89e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 22 FFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDAGIVTFDVndlSYDKAAGWTNYPKGMMDE 101
Cdd:PRK00555 5 YAAPGRINLIGEHTDYNLGFALPIALPQRTVVTFTPEHTDAITASSDRADGSARIPLDT---TPGQVTGWAAYAAGVIWA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 102 IAKTGVKFDHGfDFYVHGNMPDGAGLSSSASIE--LLTGIMLNTGFNlgISQLDLVKIGQKCENNYVGVNSGIMDQFAVG 179
Cdd:PRK00555 82 LRGAGHPVPGG-AMSITSDVEIGSGLSSSAALEcaVLGAVGAATGTR--IDRLEQARLAQRAENEYVGAPTGLLDQLAAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 180 MGKKDQAILLDTNTMDYSYAPVKLG--NNVIVIMNTNKRRELADSKYNERRSECEealrRLQTKLDIKSLGDLTnDQFDE 257
Cdd:PRK00555 159 FGAPKTALLIDFRDLTVRPVAFDPDaaGVVLLLMDSRARHRHAGGEYAARRASCE----RAAADLGVSSLRAVQ-DRGLA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 258 AAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAETAWKQpGVLGARMT 337
Cdd:PRK00555 234 ALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHASMRDDFEITTERIDLIADSAVRA-GALGARMT 312
|
330 340
....*....|....*....|....
gi 489738969 338 GAGFGGCGIAIVDKDQVDAFKENV 361
Cdd:PRK00555 313 GGGFGGCVIALVPADRAEDVADTV 336
|
|
| PLN02865 |
PLN02865 |
galactokinase |
20-366 |
3.59e-53 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 181.92 E-value: 3.59e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 20 RVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPdaGIVTFDVNDLSY---------DKAAG 90
Cdd:PLN02865 31 RVVVSPYRICPLGAHIDHQGGTVSAMTINKGILLGFVPSGDPEVLLRSAQFE--GEVRFRVDEIQHpianvssdsKEESN 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 91 WTNYPKGMMDEIAKTGVKFDHGFDFYVHG-NMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENNYVGVN 169
Cdd:PLN02865 109 WGDYARGAVYALQSRGHALSQGITGYISGsEGLDSSGLSSSAAVGVAYLLALENANNLTVSPEDNIELDRLIENEYLGLR 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 170 SGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNN------VIVIMNTNKRRELAD-SKYNERRSECEEALRRLQT-- 240
Cdd:PLN02865 189 NGILDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQQPggekpfKILLAFSGLRHALTNkPGYNLRVSECQEAARFLLEas 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 241 -KLDIKSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELD 319
Cdd:PLN02865 269 gNDELEPLLCNVEPEVYEAHKCKLEAVLARRAEHYFSENMRVIKGVEAWASGNLEEFGKLISASGLSSIENYECGCEPLI 348
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 489738969 320 TLAETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYR 366
Cdd:PLN02865 349 QLYEILLKAPGVYGARFSGAGFRGCCVAFVDAEMAEEAASFVRDEYE 395
|
|
| PLN02521 |
PLN02521 |
galactokinase |
6-365 |
3.14e-46 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 165.27 E-value: 3.14e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 6 LKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTygVYAPRTDTTVRMYS-ANIPD-AGIVTFDVN-D 82
Cdd:PLN02521 35 LKAAFVEVYGAKPDLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDT--IVAIRRAEGSKKLRiANVNDkYTTCTFPADpD 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 83 LSYDKAA-GWTNY----PKGMMDEIAKTG--VKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLV 155
Cdd:PLN02521 113 QEVDLANhKWGNYficgYKGVFEFLKSKGvdVGPPVGLDVVVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVA 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 156 KIGQKCEnNYVGVNSGIMDQFAVGMGKKDQAILLDTNtmdysyaPVKlGNNVI-------VIMNT---NKRRELADSKYN 225
Cdd:PLN02521 193 QFTCKCE-RHIGTQSGGMDQAISIMAQQGVAKLIDFN-------PVR-ATDVQlpaggtfVIANSlaeSNKAVTAATNYN 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 226 ERRSEC---------------EEALRRLQTKLDIKSL------------------------------------GDLTNDQ 254
Cdd:PLN02521 264 NRVVECrlaaivlavklgmsaEEAISKVKTLSDVEGLcvsfagshgssdpavavkellhegpytaeeieeilgESLTSIF 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 255 FDEAAYL--INDET---LIKRARHAVFENQR--AIRAT---KALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAET 324
Cdd:PLN02521 344 KNSPTSLavLKAAKhfkLHQRAVHVYSEAKRvhAFRDTvssSLSEEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKV 423
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 489738969 325 AwKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVY 365
Cdd:PLN02521 424 C-RDNGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKF 463
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
4-383 |
1.92e-34 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 132.64 E-value: 1.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 4 SDLKQEFTEAFDTKPE-----RVF-FSPGRINLIGEHTDYNGGHVFPCAITIGTY---GVYAPRTDTTVRMysANIPDAG 74
Cdd:PTZ00290 16 STLKPIFLETFKVENDadvewLLFtFAPGRVNFIGEHVDYMGGYVCPAAVLEGCHilvGRVKHFCDHKLRF--ATETDEH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 75 IVTFDVNDLSYDKAagWTNYPKGMMD-EIAKTGVKFD----HGFDFYVHGNMPDGAGLSSSAS--IELLTGI-------- 139
Cdd:PTZ00290 94 FVLDHLGGAKHNKA--WTTFVRGAATlRLNRLGVAIDapslQGVCMVVHGTLPMGAGMSASASfgVALLNAIntvvtrry 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 140 ---MLNTGFNLGI-------SQLDLVKIGQKCENNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVK--LGNNV 207
Cdd:PTZ00290 172 kgcPTSPGRRYSIlppmskeELIELAKQARRIETEFCGVNVGIMDQFISAFAEEDKFMFLDCKSLTFESHDMTplLGDGA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 208 -IVIMNTNKRRELADSK---YNERRSECEEALRRL-QTKLDIK--SLGDLTND--QF----DEAAYLINDETLI-----K 269
Cdd:PTZ00290 252 cFLLIDSMIKHDLLGGTagmYNTVRSDQEGAQKKIgKHRYRGKpfTFSDLVRNpkKYtfdgDVVAFMESCKPLMtpgefE 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 270 RARHAVFENQRAI------RATKALADDD-LTTFGELVTASHVSLHFDYEVTGKELDTLAETAWKQPGVLGARMTGAGFG 342
Cdd:PTZ00290 332 RGTYNIMEQIRTLefiklnDPELPLSREErFRKAGEILNAGHQGMRDLMKITTPELDFIHELINEEKGVAGGRMMGGGFG 411
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 489738969 343 GCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADG 383
Cdd:PTZ00290 412 GCIILLLKKNAVDRVVAHVREKFKARFGVENDVYPVVAGDG 452
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
8-57 |
1.98e-23 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 91.75 E-value: 1.98e-23
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 489738969 8 QEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAP 57
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
24-349 |
5.94e-18 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 82.97 E-value: 5.94e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 24 SPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDA-GIVTFDVNDLSYDKAAgwtnypkgmmdeI 102
Cdd:COG1577 1 APGKLILFGEHAVVYGQPAIAVAVDRRATVTVEPSDDDKLRIESPDLGGTlDLDPLADAALRYIKAA------------I 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 103 AKTGVKFD---HGFDFYVHGNMPDGAGLSSSASIelLTGIM--LNTGFNLGISQLDLVKIGQKCEnNYVGVNSGIMDQFA 177
Cdd:COG1577 69 EAALEYLGlplKGFDIEIDSEIPRKRGLGSSAAV--AVAVIraLAAFYGVELSKEELFKLALEAE-KIVHGNPSGLDTAA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 178 VGMGkkdQAILLDTNTmdySYAPVKLGNNV-IVIMNTNKRRELAD--SKYNERRSECEEALRRLqtkldIKSLGDLTNdq 254
Cdd:COG1577 146 STYG---GPIYYQRGD---RAEPLELPKNLpLVVGDTGVPASTKElvAKVRKLKERNPELYEAF-----LEEIGDLVE-- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 255 fdeaaylindetlikrarhavfenqraiRATKALADDDLTTFGELVTASHVSLhFDYEVTGKELDTLAETAwKQPGVLGA 334
Cdd:COG1577 213 ----------------------------EAIEALEEGDLEALGELMNENHGLL-RALGVSTPELDRLVEAA-RKAGALGA 262
|
330
....*....|....*
gi 489738969 335 RMTGAGFGGCGIAIV 349
Cdd:COG1577 263 KLTGAGGGGCVIALA 277
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
24-347 |
6.32e-16 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 76.95 E-value: 6.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 24 SPGRINLIGEHTDYNGGHVFPCAITIgtygvyapRTDTTVRMYSanipDAGIVTFDVNDLSYDKA-AGWTNYPKGMMDEI 102
Cdd:TIGR00549 1 APGKIILFGEHAVVYGEPAIAAPIPL--------RTTVTVIESS----DGSFIESDLGRGSLDDApDELDGLKYVLAEFL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 103 AKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENNYVGVNSGImDQFAVGMGK 182
Cdd:TIGR00549 69 SRFSELNPPPLEITIESEIPPGRGLGSSAAVAVALIRALADYFGSELSKEELAELANEAEKIAHGKPSGI-DTATSTSGG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 183 kdqAILLDTNTMDYSYAPVKLGNnvIVIMNTNKRRELAD--SKYNERRSECEEALRRLqtkldIKSLGDLTNDqfdeaay 260
Cdd:TIGR00549 148 ---PVYFEKGEGEFTKLISLDGY--FVIADTGVSGSTKEavARVRQLLERFPELIDSI-----MDAIGELTLE------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 261 lindetlikrarhavfenqrairATKALADDDLTTFGELVTASHVSLHfDYEVTGKELDTLAETAWKQpGVLGARMTGAG 340
Cdd:TIGR00549 211 -----------------------AKAALQDGDVESLGELMNINQGLLK-ALGVSHPKLDQLVEIARKA-GALGAKLTGAG 265
|
....*..
gi 489738969 341 FGGCGIA 347
Cdd:TIGR00549 266 GGGCMIA 272
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
24-369 |
1.08e-15 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 77.02 E-value: 1.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 24 SPGRINLIGEHTDYNGGHVFPCAITIGTYgVYAPRTDTTVRMYSAnIPDAGIVtfdvndLSYDKAAgwtnyPKGMMDEIA 103
Cdd:PRK03926 6 APGKIYLFGEHAVVYGKPAIACAIDLRTY-VRAEFNDDSIYIESD-YGKTGEK------HPYVSAA-----IEKMREEAD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 104 KTGVKFDhgfdfyVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENNYVGVNSGImDQFAVGMGkk 183
Cdd:PRK03926 73 KDGVTVS------ITSQIPVGSGLGSSAAVTVATIGALNRLLGLGLSLEEIAKLGHKVELLVQGAASPT-DTYVSTMG-- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 184 DQAILLDTNTMDysyaPVKLGnnvIVIMNTNK---RRELAdSKYNERRSECEEALRRLqtkldIKSLGDLTNdqfdeaay 260
Cdd:PRK03926 144 GFVTIPDRKKLP----FPECG---IVVGYTGSsgsTKELV-ANVRKLKEEYPELIEPI-----LSSIGKISE-------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 261 lindetlikrarhavfenqraiRATKALADDDLTTFGELVTASHVSLHfDYEVTGKELDTLAETAwKQPGVLGARMTGAG 340
Cdd:PRK03926 203 ----------------------KGEELILSGDYVSLGELMNINQGLLD-ALGVSTKELSELIYAA-RTAGALGAKITGAG 258
|
330 340
....*....|....*....|....*....
gi 489738969 341 FGGCGIAIVDKDQVDAFKENVGKVYRDTI 369
Cdd:PRK03926 259 GGGCMVALAAPEKQSEVATAIKIAGGKPI 287
|
|
| COG2605 |
COG2605 |
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ... |
24-359 |
8.78e-14 |
|
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain] Cd Length: 328 Bit Score: 71.36 E-value: 8.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 24 SPGRINLIGEHTDY------NGGHVFPCAITIGTYGVYAPRTDTTVRMYSAnipDAGIVTF--DVNDLsydkaagwtnyP 95
Cdd:COG2605 5 APLRISFAGGGTDLppyyleHGGAVLNAAIDKYAYVTLEPRFDGKIRLSSS---DTERVETvdEDDDI-----------P 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 96 KGMMDEIAKTgVKFDHGFDFYVHGNMPDGAGLSSSASieLLTGIM--LNTGFNLGISQLDLVKIGQKCENNYVGVNSGIM 173
Cdd:COG2605 71 HPVIREALKL-FGIGDGLEITTDSDAPAGSGLGSSSA--LTVALLnaLHALLGLPLSPYDLARLAYEIERNDLGEPGGKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 174 DQFAVGMG-------KKDQAIlldtntmdySYAPVKLGNNVI-------VIMNTNKRRELAD------SKYNERRSECEE 233
Cdd:COG2605 148 DQYAAAFGgfnfiefGPDGRV---------IVNPLRISPEILnelesnlLLFYTGITRESSDilkeqvKNVEDGDEATLE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 234 ALRRlqtkldIKSLGD-----LTNDQFDEAAYLINDETLIKrarhavfenqrairatKALADDdlttfgelvtashvslh 308
Cdd:COG2605 219 ALHE------MKELALemkeaLLKGDLDEFGELLNEGWELK----------------KRLASG----------------- 259
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 489738969 309 fdyeVTGKELDTLAETAwKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKE 359
Cdd:COG2605 260 ----ISNPAIDEIYELA-RKAGALGGKLLGAGGGGFLLFYAPPERREAVRE 305
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
114-182 |
1.04e-12 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 62.57 E-value: 1.04e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489738969 114 DFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNlgisqLDLVKIGQKCENNYVGVNSGIMDQFAVGMGK 182
Cdd:pfam00288 1 DIEIESNIPLGAGLGSSAALAVALLLALNELFG-----LPLAKLALEAEELAGGGRGGGMDVAASLYGG 64
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
284-367 |
2.45e-10 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 56.71 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 284 ATKALADDDLTTFGELVTASHVSL--HFDYEVTGKELDTLAETAwKQPGvLGARMTGAGFGGCGIAIV-DKDQVDAFKEN 360
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEAL-LELG-LGAKLSGSGGGPTVFALFkDEDDAEEVARA 78
|
....*..
gi 489738969 361 VGKVYRD 367
Cdd:pfam08544 79 LREAGKK 85
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
274-361 |
1.04e-05 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 46.77 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 274 AVFENQRAI--RATKALADDDLTTFGELVTASHvSLHFDYEVTGKELDTLAETAwKQPGVLGARMTGAGFGGCGIAI-VD 350
Cdd:PTZ00298 218 RLLENYNACvsEAKEALQKGNLFRVGELMNANH-DLCQKLTVSCRELDSIVQTC-RTYGALGAKMSGTGRGGLVVALaAS 295
|
90
....*....|.
gi 489738969 351 KDQVDAFKENV 361
Cdd:PTZ00298 296 EDQRDAIAKAV 306
|
|
| PRK04181 |
PRK04181 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional |
113-160 |
2.89e-03 |
|
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional
Pssm-ID: 235243 Cd Length: 257 Bit Score: 39.17 E-value: 2.89e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 489738969 113 FDFY---VHGNMPDGAGL---SSSASIELltgIMLNTGFNLGISQLDLVKIGQK 160
Cdd:PRK04181 84 FKKKaieVEKNIPTGAGLgggSSDAATFL---LMLNEILNLKLSLEELAEIGSK 134
|
|
| thrB |
TIGR00191 |
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine ... |
76-238 |
4.26e-03 |
|
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine kinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.P.aeruginosa homoserine kinase seems not to be homologous (see PROSITE:PDOC0054) [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 129295 [Multi-domain] Cd Length: 302 Bit Score: 38.54 E-value: 4.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 76 VTFDVNDLSYDKAA-GWTNYPKGMMDEIA-KTGVKF--DHG-----FDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFN 146
Cdd:TIGR00191 35 VAQESDDTEIEAEGeGVEKIPTEPTDNLIyQVAKRFldQLGirmppVKVTLEKNIPLGRGLGSSAAAIVAALAAANELCG 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489738969 147 LGISQLDLVKIGQKCENNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYApvklgnnVIVI----MNTNKRRELADS 222
Cdd:TIGR00191 115 LPLSKERLLDYASELEGHPDNVAPALLGGFQLAFVEDDKLEVLKIPIFSKLDW-------VLAIpnieVSTAEARAVLPK 187
|
170
....*....|....*.
gi 489738969 223 KYneRRSECEEALRRL 238
Cdd:TIGR00191 188 AY--PRQDLVFNLSHL 201
|
|
| |
